BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O35490 (407 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1UMY-A nrPDB 825 0.0 1LT8-A nrPDB 793 0.0 1Q7Q-A nrPDB 82 4e-16 4CCZ-A nrPDB 61 1e-09 5DML-A nrPDB 53 2e-07 1F8S-A nrPDB 31 1.1 5YSW-A nrPDB 30 2.4 2UYY-A nrPDB 28 4.8 2I9I-A nrPDB 28 7.8 5ED8-A nrPDB 28 9.3 >1UMY-A nrPDB Length = 407 Score = 825 bits (2131), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/407 (97%), Positives = 401/407 (98%) Query: 1 MAPVAGKKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 MAP+AGKKAK+GILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPIAGKKAKRGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKP 180 GVSQTPSYLSCKSE EVKKIF QQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALK SGKP Sbjct: 121 GVSQTPSYLSCKSETEVKKIFHQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKTSGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARL 240 +AATMCIGPEGDLHGV PGECAVRLVKAGA+IVGVNCHFDPS SLQT+KLMKEGLEAARL Sbjct: 181 IAATMCIGPEGDLHGVSPGECAVRLVKAGAAIVGVNCHFDPSTSLQTIKLMKEGLEAARL 240 Query: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 Query: 361 RPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFEKQKFKSAQ 407 RPYNPSMS+PDAWGVTKGAAELMQQKEATTEQQLR LFEKQKFKSAQ Sbjct: 361 RPYNPSMSKPDAWGVTKGAAELMQQKEATTEQQLRALFEKQKFKSAQ 407 >1LT8-A nrPDB Length = 406 Score = 793 bits (2047), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/405 (93%), Positives = 391/405 (96%) Query: 1 MAPVAGKKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 MAPV GKKAKKGILERLNAGE+VIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYV EKISGQ+VNEAA DIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAAADIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKP 180 GVSQTPSYLS KSE EVKK+F QQLEVFMKKNVDFLIAEYFEHVEEAVWAVE L ASGKP Sbjct: 121 GVSQTPSYLSAKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARL 240 VAATM IGPEGDLHGVPPGE AVRLVKAGASI+GVNCHFDP++SL+TVKLMKEGLEAA+L Sbjct: 181 VAATMAIGPEGDLHGVPPGEAAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQL 240 Query: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KA+LMSQPLAYHTPD KQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAHLMSQPLAYHTPDANKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPW+RARARKEYW+NLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 Query: 361 RPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFEKQKFKS 405 RPYNPSMS+PD WGVTKG AELMQQKEATTEQQL+ELFEKQKFKS Sbjct: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKS 405 >1Q7Q-A nrPDB Length = 566 Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 80/301 (26%), Positives = 134/301 (44%), Gaps = 32/301 (10%) Query: 14 LERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT 73 + +L + V++ DG + K GY E ++ P+ V ++HR ++ +GS+V+ T Sbjct: 7 VSKLLSERVLLLDGAYGTEFMKYGY---DDLPEELNIKAPDVVLKVHRSYIESGSDVILT 63 Query: 74 FTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAGGVSQT---PSYLS 130 TF A+ KL G + +K+ + A IAR+ A G+ LV G + T P L Sbjct: 64 NTFGATRMKLRKHG--LEDKL--DPIVRNAVRIARRAA--GEKLVFGDIGPTGELPYPLG 117 Query: 131 CKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPV--AATMCIG 188 E + FR+ +E+ +++ VD +I E F + E AV A + + V A M Sbjct: 118 STLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFD 177 Query: 189 PEG-DLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQ 247 +G L G P A+ + +G+NC P + + + +E L Y + Sbjct: 178 EKGRSLTGTDPANFAITFDELDIDALGINCSLGPE---EILPIFQE------LSQY--TD 226 Query: 248 PLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHI 307 P+ GK ++ + + L+P D + Y LGV GGCCG P H+ Sbjct: 227 KFLVVEPNAGKP-IVENGKTVYPLKPH-----DFAVHIDSYYELGVNIFGGCCGTTPEHV 280 Query: 308 R 308 + Sbjct: 281 K 281 >4CCZ-A nrPDB Length = 644 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 71/306 (23%), Positives = 137/306 (44%), Gaps = 48/306 (15%) Query: 49 AVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIAR 108 ++ P+ + Q+H+E+L AG+++++T TF ++ + +Y E ++ ++N + +AR Sbjct: 58 SITQPDVIYQIHKEYLLAGADIIETNTFSSTSIA---QADYGLEHLA-YRMNMCSAGVAR 113 Query: 109 QVADEGDA------LVAGGVSQTPSYLSCKSEV-----------EVKKIFRQQLEVFMKK 151 + A+E VAG + T LS V E+ + +++Q + + Sbjct: 114 KAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDG 173 Query: 152 NVDFLIAEYF---EHVEEAVWAVEAL---KASGKPVAAT-MCIGPEGDLHGVPPGECAVR 204 VD L+ E + + A++A++ L K + +P+ + + G GE V Sbjct: 174 GVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVI 233 Query: 205 LVKAGASI-VGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFID 263 V G + +G+NC + ++++ + AY++ P A P+ F D Sbjct: 234 SVSHGEPLCIGLNCALGAAEMRPFIEIIGKC-----TTAYVLCYPNA-GLPNT----FGD 283 Query: 264 LPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPP 323 E P + ++ +A + V +GGCCG P HIR IAE + + +PP Sbjct: 284 YDETPSMMAKH------LKDFAMDGL---VNIVGGCCGSTPDHIREIAEAVKNCKPRVPP 334 Query: 324 ASEKHG 329 A+ G Sbjct: 335 ATAFEG 340 >5DML-A nrPDB Length = 310 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 75/323 (23%), Positives = 125/323 (38%), Gaps = 56/323 (17%) Query: 17 LNAGEVVIGDGGFVFALEKRGYVKAGP-WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFT 75 L+ ++++ DG LE RG A W+ + VE+PE +R++H ++ RAG+ T + Sbjct: 11 LDKQDILLLDGAMATELEARGCNLADSLWSAKVLVENPELIREVHLDYYRAGAQCAITAS 70 Query: 76 FYASEDKLENRGNYVAEKISGQKVNEAACDIARQVAD--------EGDALVAGGVSQTPS 127 + A+ RG ++ + + + ++AR+ + G LVAG V + Sbjct: 71 YQATPAGFAARG---LDEAQSKALIGKSVELARKAREAYLAENPQAGTLLVAGSVGPYGA 127 Query: 128 YLSCKSE--------VEVKKIF-RQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASG 178 YL+ SE VE + F R ++E + D L E + E E L A Sbjct: 128 YLADGSEYRGDYHCSVEAFQAFHRPRVEALLDAGADLLACETLPNFSEIEALAELLTAYP 187 Query: 179 KPVA-ATMCIGPEGDLHGVPPGECAVRLVKAGASIV--GVNCHFDPSVSLQTVKLMKEGL 235 + A + + L P V L+ +V G+NC ++L+ + L Sbjct: 188 RARAWFSFTLRDSEHLSDGTPLRDVVALLAGYPQVVALGINC-----IALENTTAALQHL 242 Query: 236 EAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRW--------DIQKYARE 287 L PL + P+ G+ V+ W + Y + Sbjct: 243 HG------LTVLPLVVY-PNSGEH------------YDAVSKTWHHHGEHCAQLADYLPQ 283 Query: 288 AYNLGVRYIGGCCGFEPYHIRAI 310 G R IGGCC P I A+ Sbjct: 284 WQAAGARLIGGCCRTTPADIAAL 306 >1F8S-A nrPDB Length = 498 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/99 (23%), Positives = 39/99 (39%), Gaps = 16/99 (16%) Query: 273 PRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWG 332 P V +W + KYA +GG F PY + ++ L +G + A E Sbjct: 414 PSVIQKWSLDKYA----------MGGITTFTPYQFQHFSDPLTASQGRIYFAGEYTAQAH 463 Query: 333 SGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSRPD 371 +D K +RA +++ +AS P +S + Sbjct: 464 GWIDSTIKSGLRAA------RDVNLASENPSGIHLSNDN 496 >5YSW-A nrPDB Length = 441 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 38/163 (23%), Positives = 64/163 (39%), Gaps = 30/163 (18%) Query: 43 PWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEA 102 PW E + PE +L + RAGS + + KL + + + +++ E Sbjct: 104 PWFKELS---PEFRERLRDDKARAGSFINMDPPEHTRYRKL------LTGQFTVRRIREL 154 Query: 103 ACDIARQVADEGDALVAGGVSQ---------TPSYLSCK---SEVEVKKIFRQQLEVFMK 150 I VA DA++AGG + PS + C+ E + F+Q+ ++ Sbjct: 155 GARIDEIVAGRVDAMLAGGTTADLMTEFAFPAPSLMICELLGVRYEDRAEFQQRASALLQ 214 Query: 151 KNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDL 193 N V EAV +AL+A + + P GD+ Sbjct: 215 MNAP---------VAEAVKNADALRAFMQALVTDKRANPAGDI 248 >2UYY-A nrPDB Length = 316 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 182 AATMCIGPEGDLHGVPPGECAVRLVKAGASIV 213 A + +GP G L G+ PG+C V + A V Sbjct: 100 AKDLVLGPSGVLQGIRPGKCYVDMSTVDADTV 131 >2I9I-A nrPDB Length = 254 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 119 AGGVSQTPS----YLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEAL 174 +GG++ + S YL E + KI + V MKK V L E + EA+ ++ Sbjct: 179 SGGLNSSNSIIHEYLEKNKEDAIHKILNRMYAVVMKKAVTELTKENIDKYREAIDRMKGF 238 Query: 175 KAS 177 K+S Sbjct: 239 KSS 241 >5ED8-A nrPDB Length = 268 Score = 27.7 bits (60), Expect = 9.3, Method: Compositional matrix adjust. Identities = 30/141 (21%), Positives = 58/141 (41%), Gaps = 28/141 (19%) Query: 46 PEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACD 105 P + + P+ +RQ A S ++Q +A +LEN+ ++ G+ EAA Sbjct: 2 PGSEFQFPDWIRQFLLGDRGARSGLLQRDEMHAQLQELENKILTKMAEMQGKSAREAAAS 61 Query: 106 IARQVADEGDALVAGGVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVE 165 + + + EG V +E +V +I +Q L+ + + + + +Y Sbjct: 62 LGQILQKEGIVGV--------------TEEQVHRIVKQALQRYSEDRIG--MVDY----- 100 Query: 166 EAVWAVEALKASGKPVAATMC 186 AL++ G V +T C Sbjct: 101 -------ALESGGASVISTRC 114 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1UMY-A nrPDB 671 0.0 1LT8-A nrPDB 650 0.0 1Q7Q-A nrPDB 313 1e-85 4CCZ-A nrPDB 294 5e-80 5DML-A nrPDB 282 1e-76 Sequences not found previously or not previously below threshold: 4QI6-A nrPDB 38 0.007 4QI5-A nrPDB 38 0.007 1VRD-A nrPDB 36 0.044 5EF4-A nrPDB 32 0.48 1F8S-A nrPDB 32 0.60 3AJB-A nrPDB 31 0.82 3DSD-A nrPDB 31 1.2 6B5K-A nrPDB 28 6.8 CONVERGED! >1UMY-A nrPDB Length = 407 Score = 671 bits (1730), Expect = 0.0, Method: Composition-based stats. Identities = 395/407 (97%), Positives = 401/407 (98%) Query: 1 MAPVAGKKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 MAP+AGKKAK+GILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPIAGKKAKRGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKP 180 GVSQTPSYLSCKSE EVKKIF QQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALK SGKP Sbjct: 121 GVSQTPSYLSCKSETEVKKIFHQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKTSGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARL 240 +AATMCIGPEGDLHGV PGECAVRLVKAGA+IVGVNCHFDPS SLQT+KLMKEGLEAARL Sbjct: 181 IAATMCIGPEGDLHGVSPGECAVRLVKAGAAIVGVNCHFDPSTSLQTIKLMKEGLEAARL 240 Query: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 Query: 361 RPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFEKQKFKSAQ 407 RPYNPSMS+PDAWGVTKGAAELMQQKEATTEQQLR LFEKQKFKSAQ Sbjct: 361 RPYNPSMSKPDAWGVTKGAAELMQQKEATTEQQLRALFEKQKFKSAQ 407 >1LT8-A nrPDB Length = 406 Score = 650 bits (1677), Expect = 0.0, Method: Composition-based stats. Identities = 378/405 (93%), Positives = 391/405 (96%) Query: 1 MAPVAGKKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 MAPV GKKAKKGILERLNAGE+VIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH Sbjct: 1 MAPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH 60 Query: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAG 120 REFLRAGSNVMQTFTFYASEDKLENRGNYV EKISGQ+VNEAA DIARQVADEGDALVAG Sbjct: 61 REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAAADIARQVADEGDALVAG 120 Query: 121 GVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKP 180 GVSQTPSYLS KSE EVKK+F QQLEVFMKKNVDFLIAEYFEHVEEAVWAVE L ASGKP Sbjct: 121 GVSQTPSYLSAKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP 180 Query: 181 VAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARL 240 VAATM IGPEGDLHGVPPGE AVRLVKAGASI+GVNCHFDP++SL+TVKLMKEGLEAA+L Sbjct: 181 VAATMAIGPEGDLHGVPPGEAAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQL 240 Query: 241 KAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 KA+LMSQPLAYHTPD KQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC Sbjct: 241 KAHLMSQPLAYHTPDANKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC 300 Query: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASG 360 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPW+RARARKEYW+NLRIASG Sbjct: 301 GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG 360 Query: 361 RPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFEKQKFKS 405 RPYNPSMS+PD WGVTKG AELMQQKEATTEQQL+ELFEKQKFKS Sbjct: 361 RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKS 405 >1Q7Q-A nrPDB Length = 566 Score = 313 bits (801), Expect = 1e-85, Method: Composition-based stats. Identities = 81/312 (25%), Positives = 137/312 (43%), Gaps = 32/312 (10%) Query: 14 LERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT 73 + +L + V++ DG + K GY E ++ P+ V ++HR ++ +GS+V+ T Sbjct: 7 VSKLLSERVLLLDGAYGTEFMKYGY---DDLPEELNIKAPDVVLKVHRSYIESGSDVILT 63 Query: 74 FTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAGGVSQT---PSYLS 130 TF A+ KL G + +K+ + A IAR+ A G+ LV G + T P L Sbjct: 64 NTFGATRMKLRKHG--LEDKL--DPIVRNAVRIARRAA--GEKLVFGDIGPTGELPYPLG 117 Query: 131 CKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVA--ATMCIG 188 E + FR+ +E+ +++ VD +I E F + E AV A + + V A M Sbjct: 118 STLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFD 177 Query: 189 PEGD-LHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQ 247 +G L G P A+ + +G+NC P + + + +E L Y + Sbjct: 178 EKGRSLTGTDPANFAITFDELDIDALGINCSLGPE---EILPIFQE------LSQY--TD 226 Query: 248 PLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHI 307 P+ GK ++ + + L+P D + Y LGV GGCCG P H+ Sbjct: 227 KFLVVEPNAGKP-IVENGKTVYPLKPH-----DFAVHIDSYYELGVNIFGGCCGTTPEHV 280 Query: 308 RAIAEELAPERG 319 + + L + Sbjct: 281 KLFRKVLGNRKP 292 >4CCZ-A nrPDB Length = 644 Score = 294 bits (752), Expect = 5e-80, Method: Composition-based stats. Identities = 78/361 (21%), Positives = 153/361 (42%), Gaps = 62/361 (17%) Query: 8 KAKKGILERLNAGEVVIGDGGFVFALEK--------RGYVKAGPWTPE------AAVEHP 53 K + + + +++ DGG +++ RG P ++ P Sbjct: 3 KTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQP 62 Query: 54 EAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADE 113 + + Q+H+E+L AG+++++T TF ++ + +Y E ++ ++N + +AR+ A+E Sbjct: 63 DVIYQIHKEYLLAGADIIETNTFSSTSIA---QADYGLEHLA-YRMNMCSAGVARKAAEE 118 Query: 114 GDA------LVAGGVSQTPSYLSCKSEVE-----------VKKIFRQQLEVFMKKNVDFL 156 VAG + T LS VE + + +++Q + + VD L Sbjct: 119 VTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 178 Query: 157 IAEYF---EHVEEAVWAVEAL---KASGKPVAAT-MCIGPEGDLHGVPPGECAVRLVKAG 209 + E + + A++A++ L K + +P+ + + G GE V V G Sbjct: 179 LIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHG 238 Query: 210 ASI-VGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFP 268 + +G+NC + ++++ + AY++ P A P+ F D E P Sbjct: 239 EPLCIGLNCALGAAEMRPFIEIIGKC-----TTAYVLCYPNA-GLPNT----FGDYDETP 288 Query: 269 FGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKH 328 + ++ +A + V +GGCCG P HIR IAE + + +PPA+ Sbjct: 289 SMMAKH------LKDFAMDGL---VNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFE 339 Query: 329 G 329 G Sbjct: 340 G 340 >5DML-A nrPDB Length = 310 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 73/315 (23%), Positives = 122/315 (38%), Gaps = 40/315 (12%) Query: 17 LNAGEVVIGDGGFVFALEKRGYVKAGP-WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFT 75 L+ ++++ DG LE RG A W+ + VE+PE +R++H ++ RAG+ T + Sbjct: 11 LDKQDILLLDGAMATELEARGCNLADSLWSAKVLVENPELIREVHLDYYRAGAQCAITAS 70 Query: 76 FYASEDKLENRGNYVAEKISGQKVNEAACDIARQVAD--------EGDALVAGGVSQTPS 127 + A+ RG ++ + + + ++AR+ + G LVAG V + Sbjct: 71 YQATPAGFAARG---LDEAQSKALIGKSVELARKAREAYLAENPQAGTLLVAGSVGPYGA 127 Query: 128 YLSCKSE--------VEVKKIF-RQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASG 178 YL+ SE VE + F R ++E + D L E + E E L A Sbjct: 128 YLADGSEYRGDYHCSVEAFQAFHRPRVEALLDAGADLLACETLPNFSEIEALAELLTAYP 187 Query: 179 KPVA-ATMCIGPEGDLHGVPPGECAVRLVKAGASIV--GVNCHFDPSVSLQTVKLMKEGL 235 + A + + L P V L+ +V G+NC ++L+ + L Sbjct: 188 RARAWFSFTLRDSEHLSDGTPLRDVVALLAGYPQVVALGINC-----IALENTTAALQHL 242 Query: 236 EAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRY 295 L PL + P+ G+ + Y + G R Sbjct: 243 HG------LTVLPLVVY-PNSGEH----YDAVSKTWHHHGEHCAQLADYLPQWQAAGARL 291 Query: 296 IGGCCGFEPYHIRAI 310 IGGCC P I A+ Sbjct: 292 IGGCCRTTPADIAAL 306 >4QI6-A nrPDB Length = 807 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 23/179 (12%), Positives = 54/179 (30%), Gaps = 29/179 (16%) Query: 37 GYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT--FTFYASEDKLENRGNYVAEKI 94 GY + + HP+ V +F A + +++ ++ S + + + Sbjct: 525 GYNLDDHLNTDTVISHPDVVF---YDFYEAWDDPIESDKNSYLESRTGILAQAAPNIGPM 581 Query: 95 SGQKVNEAACDIARQVADEGDALVAGGVSQTP-------SYLSCKSEVEVKKIFRQQLEV 147 +++ A I RQ+ + A V G + YL + + L Sbjct: 582 FWEEIVGAD-GIVRQL--QWTARVEGSLGAPNGHTMTMSQYLGRGATSRGRMTITPSLTT 638 Query: 148 FM------------KKNVDFLI--AEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGD 192 + + + +I ++V W + + +M + P Sbjct: 639 IVSDVPYLKDPNDKEAVIQGIINLQNALQNVANLTWLFPNSTITPREYVESMVVSPSNR 697 >4QI5-A nrPDB Length = 585 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 23/179 (12%), Positives = 54/179 (30%), Gaps = 29/179 (16%) Query: 37 GYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQT--FTFYASEDKLENRGNYVAEKI 94 GY + + HP+ V +F A + +++ ++ S + + + Sbjct: 303 GYNLDDHLNTDTVISHPDVVF---YDFYEAWDDPIESDKNSYLESRTGILAQAAPNIGPM 359 Query: 95 SGQKVNEAACDIARQVADEGDALVAGGVSQTP-------SYLSCKSEVEVKKIFRQQLEV 147 +++ A I RQ+ + A V G + YL + + L Sbjct: 360 FWEEIVGAD-GIVRQL--QWTARVEGSLGAPNGHTMTMSQYLGRGATSRGRMTITPSLTT 416 Query: 148 FM------------KKNVDFLI--AEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGD 192 + + + +I ++V W + + +M + P Sbjct: 417 IVSDVPYLKDPNDKEAVIQGIINLQNALQNVANLTWLFPNSTITPREYVESMVVSPSNR 475 >1VRD-A nrPDB Length = 494 Score = 35.6 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 49/131 (37%), Gaps = 18/131 (13%) Query: 112 DEGDALVAGGVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFE-HVEEAVWA 170 ++G LV V +P + +++E +K VD ++ + H + Sbjct: 222 EKGRLLVGAAVGTSPETM-------------ERVEKLVKAGVDVIVIDTAHGHSRRVIET 268 Query: 171 VEALKA-SGK-PVAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTV 228 +E +KA PV A PEG + G AV+ V G + V + + Sbjct: 269 LEMIKADYPDLPVVAGNVATPEGTEALIKAGADAVK-VGVGPGSI-CTTRVVAGVGVPQL 326 Query: 229 KLMKEGLEAAR 239 + E E AR Sbjct: 327 TAVMECSEVAR 337 >5EF4-A nrPDB Length = 385 Score = 32.1 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 12/104 (11%) Query: 275 VATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERG--FLPPASEKHGSWG 332 VAT + + + Y+ GV G CG EP H I E+G F + +WG Sbjct: 259 VATGIQLSGHGLQFYSEGV--YTGDCGTEPNHGVGIVGYGENEKGIKFWTVKNSWGPTWG 316 Query: 333 SGLDMHTKPWIRARARKEYWQNLRIASGRPY----NPSMSRPDA 372 +H ++ ARKE + + S P NP P+ Sbjct: 317 EKGYIH----LQRGARKEGLCGVAMHSSFPIMNDPNPPKDDPNG 356 >1F8S-A nrPDB Length = 498 Score = 31.7 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 16/97 (16%) Query: 272 EPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSW 331 P V +W + KYA GG F PY + ++ L +G + A E Sbjct: 413 YPSVIQKWSLDKYAM----------GGITTFTPYQFQHFSDPLTASQGRIYFAGEYTAQA 462 Query: 332 GSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMS 368 +D K +RA AR ++ +AS P +S Sbjct: 463 HGWIDSTIKSGLRA-AR-----DVNLASENPSGIHLS 493 >3AJB-A nrPDB Length = 330 Score = 31.3 bits (69), Expect = 0.82, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 46/143 (32%), Gaps = 6/143 (4%) Query: 150 KKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVPPGECAV-RLVKA 208 K L+ Y EE AV+A S + + + D+ P + + Sbjct: 184 KDGSKPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNR 243 Query: 209 GASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFP 268 G S + N T + ++ G L + +S PLA P Q E P Sbjct: 244 GFSRLLDNMA---EFFRPTEQDLQHGNSMNSLSS--VSLPLAKIIPIVNGQIHSVCSETP 298 Query: 269 FGLEPRVATRWDIQKYAREAYNL 291 + T ++ +A Y Sbjct: 299 SHFVQDLLTMEQVKDFAANVYEA 321 >3DSD-A nrPDB Length = 349 Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 28/59 (47%), Gaps = 9/59 (15%) Query: 134 EVEVKKIFRQQLEVFMKKNVDFLIAE---------YFEHVEEAVWAVEALKASGKPVAA 183 E E + F+ LE+ +++NVDF++ +++A+ ++ K PV A Sbjct: 22 EEEFAEAFKNALEIAVQENVDFILIAGDLFHSSRPSPGTLKKAIALLQIPKEHSIPVFA 80 >6B5K-A nrPDB Length = 296 Score = 28.2 bits (61), Expect = 6.8, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 23/55 (41%) Query: 7 KKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHR 61 KK+ +G E +V + G + RG T ++ ++ + VR L R Sbjct: 187 KKSARGEYEITEVNQVYLNQGRLAVEVLARGTAWLDTGTFDSLLDAADFVRTLER 241 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.122 0.322 Lambda K H 0.267 0.0359 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,591,056 Number of Sequences: 36641 Number of extensions: 523433 Number of successful extensions: 1463 Number of sequences better than 10.0: 16 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1425 Number of HSP's gapped (non-prelim): 35 length of query: 407 length of database: 10,336,785 effective HSP length: 99 effective length of query: 308 effective length of database: 6,709,326 effective search space: 2066472408 effective search space used: 2066472408 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.9 bits)