BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O15554 (427 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6CNN-A nrPDB 870 0.0 4G27-B nrPDB 104 8e-23 1QX7-D nrPDB 77 2e-14 5VMS-A nrPDB 53 2e-07 4JTA-B nrPDB 50 2e-06 2A79-B nrPDB 49 5e-06 1ORQ-C nrPDB 47 2e-05 3EFF-K nrPDB 45 6e-05 2A9H-A nrPDB 44 1e-04 1F6G-A nrPDB 44 2e-04 3PJS-K nrPDB 40 0.002 4H33-A nrPDB 37 0.020 4XDL-A nrPDB 37 0.021 5EC2-C nrPDB 36 0.035 6CJQ-A nrPDB 35 0.051 3UKM-A nrPDB 35 0.058 2NLJ-C nrPDB 35 0.059 3FB6-C nrPDB 35 0.091 6CQ6-A nrPDB 33 0.26 5V4S-A nrPDB 33 0.31 4TWK-A nrPDB 32 0.41 5VA1-A nrPDB 32 0.53 4CHV-A nrPDB 31 1.1 4WD1-A nrPDB 30 1.8 6DNS-A nrPDB 30 1.9 6DLH-A nrPDB 30 1.9 3RBZ-A nrPDB 30 2.5 2K1E-A nrPDB 29 3.1 3UM7-A nrPDB 29 4.6 4IJ6-A nrPDB 28 5.8 >6CNN-A nrPDB Length = 427 Score = 870 bits (2247), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/427 (100%), Positives = 427/427 (100%) Query: 1 MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL 60 MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL Sbjct: 1 MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL 60 Query: 61 VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA 120 VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA Sbjct: 61 VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA 120 Query: 121 PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR 180 PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR Sbjct: 121 PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR 180 Query: 181 SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT 240 SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT Sbjct: 181 SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT 240 Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN Sbjct: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 Query: 301 FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK 360 FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK Sbjct: 301 FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK 360 Query: 361 LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP 420 LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP Sbjct: 361 LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP 420 Query: 421 EPSQQSK 427 EPSQQSK Sbjct: 421 EPSQQSK 427 >4G27-B nrPDB Length = 102 Score = 104 bits (259), Expect = 8e-23, Method: Composition-based stats. Identities = 50/95 (52%), Positives = 69/95 (72%), Gaps = 3/95 (3%) Query: 285 VARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQ 341 + RKLE KAEKHVHNFMMD Q TK +K +AA VL+E W+ YK+T+ +K HA R+HQ Sbjct: 1 MGRKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQ 60 Query: 342 RKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHM 376 RK L AI+ R V+++ RKL +Q N++VD++K + Sbjct: 61 RKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQL 95 >1QX7-D nrPDB Length = 85 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 37/78 (47%), Positives = 55/78 (70%), Gaps = 3/78 (3%) Query: 302 MMDIQYTKEMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQRKLLAAINAFRQVRLKH 358 MMD Q TK +K +AA VL+E W+ YK+T+ +K HA R+HQRK L AI+ R V+++ Sbjct: 1 MMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQ 60 Query: 359 RKLREQVNSMVDISKMHM 376 RKL +Q N++VD++K + Sbjct: 61 RKLNDQANTLVDLAKTQL 78 >5VMS-A nrPDB Length = 548 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 21/135 (15%) Query: 203 HPGRLLLGLTLGLW--LTTAWVLSVAERQAVNATGHL-----SDTLWLIPITFLTIGYGD 255 H L+ L +G + +++ + +AE+ A++++G +D LW +T TIGYGD Sbjct: 183 HRQELITTLYIGFLGLIFSSYFVYLAEKDAIDSSGEYQFGSYADALWWGVVTVTTIGYGD 242 Query: 256 VVPGTMWGKIVCLCTGVMGVCCTALLVAVV----ARKLEFNKAEKHVHNFMMDIQYTKEM 311 VP T GK + C V + AL ++ A K++ + +KH + +++ Sbjct: 243 KVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKH---------FNRQI 293 Query: 312 KESAARVLQEAWMFY 326 +AA ++Q AW Y Sbjct: 294 -PAAASLIQTAWRCY 307 >4JTA-B nrPDB Length = 514 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Query: 205 GRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGK 264 G L+ L +G+ L ++ V + + + D W ++ T+GYGD+VP T+ GK Sbjct: 344 GLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGK 403 Query: 265 IVCLCTGVMGVCCTALLVAVVARKLE-FNKAEKHVHNFMMDIQYTKEMKESAARVLQEAW 323 IV + GV AL V V+ F E +Q T K ++ L+++ Sbjct: 404 IVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSSPKIPSSPDLKKS- 462 Query: 324 MFYKHTRRKESHAARRHQRKLLAAIN----AFRQVRLKHRKLREQVNSMVDISKM 374 R S ++ ++ +N FR+ LK + V+I+KM Sbjct: 463 -------RSASTISKSDYMEIQEGVNNSNEDFREENLKTANSTLANTNYVNITKM 510 >2A79-B nrPDB Length = 499 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Query: 205 GRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGK 264 G L+ L +G+ L ++ V + + + D W ++ T+GYGD+VP T+ GK Sbjct: 329 GLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGK 388 Query: 265 IVCLCTGVMGVCCTALLVAVVARKLE-FNKAEKHVHNFMMDIQYTKEMKESAARVLQEAW 323 IV + GV AL V V+ F E +Q T K ++ L+++ Sbjct: 389 IVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKS- 447 Query: 324 MFYKHTRRKESHAARRHQRKLLAAIN----AFRQVRLKHRKLREQVNSMVDISKM 374 R S ++ ++ +N FR+ LK + V+I+KM Sbjct: 448 -------RSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKM 495 >1ORQ-C nrPDB Length = 223 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 16/108 (14%) Query: 184 ALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLW 242 A +++RF H F G ++L + G A+ + + E N++ + D LW Sbjct: 127 AADKIRFYHLF----------GAVMLTVLYG-----AFAIYIVEYPDPNSSIKSVFDALW 171 Query: 243 LIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLE 290 +T T+GYGDVVP T GK++ + + G+ LL+ V+ + Sbjct: 172 WAVVTATTVGYGDVVPATPIGKVIGIAVMLTGISALTLLIGTVSNMFQ 219 >3EFF-K nrPDB Length = 139 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 37/81 (45%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 LW T T+GYGD+ P T+WG++V + V G+ L+ A +A + E+ H Sbjct: 45 LWWSVETATTVGYGDLYPVTLWGRLVAVVVMVAGITSFGLVTAALATWFVGREQERRGHF 104 Query: 301 FMMDIQYTKEMKESAARVLQE 321 + +E R L E Sbjct: 105 VRHSEKAAEEAYTRTTRALHE 125 >2A9H-A nrPDB Length = 155 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 217 LTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGV 275 L +++ +AER A A D LW T T+GYGD+ P T+WG+ V + V G+ Sbjct: 64 LAGSYLAVLAERGAPGAALISYPDALWWSVETATTVGYGDLYPVTLWGRCVAVVVMVAGI 123 Query: 276 CCTALLVAVVARKLEFNKAEKHVH 299 L+ A VA + E+ H Sbjct: 124 TSYGLVFAAVATWFVGREQERRGH 147 >1F6G-A nrPDB Length = 160 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 36/81 (44%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 LW T T+GYGD+ P T+WG+ V + V G+ L+ A +A + E+ H Sbjct: 66 LWWSVETATTVGYGDLYPVTLWGRCVAVVVMVAGITSFGLVTAALATWFVGREQERRGHF 125 Query: 301 FMMDIQYTKEMKESAARVLQE 321 + +E R L E Sbjct: 126 VRHSEKAAEEAYTRTTRALHE 146 >3PJS-K nrPDB Length = 166 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 27/46 (58%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVA 286 LW T T+GYGD+ P T+WG++V + V G+ L+ A +A Sbjct: 72 LWWSVETATTVGYGDLYPVTLWGRLVAVVVMVAGITSFGLVTAALA 117 >4H33-A nrPDB Length = 137 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 239 DTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVAR----KLEFNKA 294 D LW +T T+GYGD+VP T G+I+ + G+ ++ + + K N + Sbjct: 46 DALWWAIVTATTVGYGDIVPVTPIGRILASIMMLFGIAFIGMITSTITNFFRCKKPTNSS 105 Query: 295 EKHVHNFMMDIQYTKEMKESAARVLQE 321 + + I T ++ + V+++ Sbjct: 106 TQRANKITQLISETPDLTKEEIAVVEQ 132 >4XDL-A nrPDB Length = 282 Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 8/93 (8%) Query: 232 NATGH--LSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 N + H L + TIGYG++ P T GKI C+ + G+ L+A + +L Sbjct: 87 NNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQL 146 Query: 290 E--FNKAEKHVHNFMMDIQYTKEMKESAARVLQ 320 F K+ V K++ ++ RV+ Sbjct: 147 GTIFGKSIARVEKVFRK----KQVSQTKIRVIS 175 >5EC2-C nrPDB Length = 125 Score = 35.8 bits (81), Expect = 0.035, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 29/59 (49%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVH 299 LW T T YGD+ P T+WG++V + V G+ L+ A +A + E+ H Sbjct: 66 LWWACETATTXAYGDLCPVTLWGRLVAVVVMVAGITSFGLVTAALATWFVGREQERRGH 124 >6CJQ-A nrPDB Length = 456 Score = 35.4 bits (80), Expect = 0.051, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 7/103 (6%) Query: 234 TGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNK 293 T +LS W I T TIGYGD+ P T + + ++G L++ +A + Sbjct: 187 TRYLSAFYWTI-TTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLVSKLD 245 Query: 294 AEKHVHNFMMD-----IQYTKEMKESAARVLQEAWMFYKHTRR 331 A K +H ++ + Y + E R++ E + + TRR Sbjct: 246 AAKLLHRERVERVTAFLSYKRISPELQRRII-EYFDYLWETRR 287 >3UKM-A nrPDB Length = 280 Score = 35.0 bits (79), Expect = 0.058, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 41/89 (46%) Query: 223 LSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLV 282 +SV + + N + L+ T GYG VP + GK C+ V+G+ T L + Sbjct: 80 VSVLSQASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFL 139 Query: 283 AVVARKLEFNKAEKHVHNFMMDIQYTKEM 311 V +++ + + V F + ++K++ Sbjct: 140 TAVVQRITVHVTRRPVLYFHIRWGFSKQV 168 >2NLJ-C nrPDB Length = 124 Score = 35.0 bits (79), Expect = 0.059, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 30/59 (50%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVH 299 LW T T+GYGD+ P T+WG+ V + V G+ L+ A +A + E+ H Sbjct: 66 LWWSVETATTVGYGDLYPVTLWGRCVAVVVVVAGITSFGLVTAALATWFVGREQERRGH 124 >3FB6-C nrPDB Length = 104 Score = 34.7 bits (78), Expect = 0.091, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 26/46 (56%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVA 286 LW T T+GYGD+ P T+WG+ V + V G+ L+ A +A Sbjct: 46 LWWSVETATTVGYGDLYPVTLWGRCVAVVVMVAGITSFGLVTAALA 91 >6CQ6-A nrPDB Length = 312 Score = 33.1 bits (74), Expect = 0.26, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 232 NATGH--LSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 N H L + + TIG+G++ P T GKI C+ ++G+ L+A V +L Sbjct: 103 NQVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQL 162 >5V4S-A nrPDB Length = 465 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 17/128 (13%) Query: 247 TFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVAR---KLEFNKAEK-----HV 298 T T+GYGD+ P T +I + ++G A ++ +A L+ KA + V Sbjct: 224 TIATVGYGDITPSTDSQRIYTIFVMILGAGVYATVIGNIASILGSLDLAKAAQRKKMAQV 283 Query: 299 HNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLK- 357 +F+ + + ++ R +++ +M+ E A + I+ R+V+++ Sbjct: 284 DSFLK----ARNISQNIRRRVRDYYMYIIDRGWGEDENALLND----LPISLRREVKIQL 335 Query: 358 HRKLREQV 365 HR L E+V Sbjct: 336 HRDLLEKV 343 >4TWK-A nrPDB Length = 283 Score = 32.3 bits (72), Expect = 0.41, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 2/53 (3%) Query: 250 TIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLE--FNKAEKHVHN 300 TIG+G++ P T GKI C+ ++G+ L+A V +L F K V + Sbjct: 118 TIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVED 170 >5VA1-A nrPDB Length = 795 Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust. Identities = 21/93 (22%), Positives = 40/93 (43%), Gaps = 8/93 (8%) Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALL---VAVVARKLEFNKAEKH 297 L+ + ++G+G+V P T KI +C ++G A + V+ + ++L A H Sbjct: 375 LYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYH 434 Query: 298 -----VHNFMMDIQYTKEMKESAARVLQEAWMF 325 V F+ Q +++ Q AW + Sbjct: 435 TQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSY 467 >4CHV-A nrPDB Length = 361 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Query: 162 LVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLT--LGLWL-T 218 LVP A L G + Y ++ L +R +F + + R L+G+T G+ L Sbjct: 83 LVPLAAFLLDGSPDWSLYCAVWLLKPLRDSTFFPVLGRVLANEARNLIGVTTLFGVVLFA 142 Query: 219 TAWVLSVAERQ-AVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCC 277 A V ER G + +W +T T GYGD +P + G+++ + G+ Sbjct: 143 VALAAYVIERDIQPEKFGSIPQAMWWAVVTLSTTGYGDTIPQSFAGRVLAGAVMMSGIGI 202 Query: 278 TALLVAVVA 286 L ++A Sbjct: 203 FGLWAGILA 211 >4WD1-A nrPDB Length = 658 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 20/99 (20%) Query: 46 MLWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVA------ 99 W+ W ++ FLV ++ +T +L F A + Q WR+A Sbjct: 309 FFWYTSTGWMMWNFLVSGLLTGTTIVLYDGSPGFPATDAQ----------WRIAERTGAT 358 Query: 100 LTGRQAAQIVLELVVCGLHPA---PVRGPPCVQDLGAPL 135 L G AA V+ G+HPA + CV G+PL Sbjct: 359 LFGTSAA-YVMACRKAGVHPARDLDLSAIQCVATTGSPL 396 >6DNS-A nrPDB Length = 623 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 16/25 (64%) Query: 70 FLLLCLIVAFHAKEVQLFMTDNGLR 94 FL+ CLI+ FH E Q+ + GLR Sbjct: 14 FLMACLIITFHKVEAQVPDPNQGLR 38 >6DLH-A nrPDB Length = 734 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 16/25 (64%) Query: 70 FLLLCLIVAFHAKEVQLFMTDNGLR 94 FL+ CLI+ FH E Q+ + GLR Sbjct: 14 FLMACLIITFHKVEAQVPDPNQGLR 38 >3RBZ-A nrPDB Length = 340 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 23/44 (52%) Query: 240 TLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVA 283 +L+ +T T+GYGD P T G + V+G+ A+ VA Sbjct: 49 SLYWTFVTIATVGYGDYSPSTPLGMYFTVTLIVLGIATFAVAVA 92 >2K1E-A nrPDB Length = 103 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%) Query: 226 AERQAVNATG-HLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAV 284 AER A A D +W T T+GYGD P T G+ V G+ AL+ A Sbjct: 29 AERGAPGAALISYPDAIWWSVETATTVGYGDRYPVTEEGRKVAEQVMKAGIEVFALVTAA 88 Query: 285 VARKLEFNKAEKHVH 299 +A + E+ H Sbjct: 89 LATDFVRREEERRGH 103 >3UM7-A nrPDB Length = 309 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 24/40 (60%) Query: 250 TIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 TIGYG+V T G++ C+ ++G+ +L+A V +L Sbjct: 129 TIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRL 168 >4IJ6-A nrPDB Length = 211 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 16/92 (17%) Query: 164 PRAVLLRSGVLLNASYRSI-GALNQVRFRHWFVAKLYM-NTHPGRLLLGLTLGLWLTTAW 221 P V + G L + Y + G L +VR RHW + + +T P R + LG+ L+ W Sbjct: 111 PHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFW 170 Query: 222 ----------VLSVAERQAV----NATGHLSD 239 V+ + ER+ V N T HL + Sbjct: 171 SFGCDNASYSVIHMEERRNVILKLNITCHLGE 202 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6CNN-A nrPDB 739 0.0 4JTA-B nrPDB 197 1e-50 2A79-B nrPDB 194 8e-50 5VMS-A nrPDB 136 2e-32 1F6G-A nrPDB 134 1e-31 3EFF-K nrPDB 131 5e-31 2A9H-A nrPDB 124 8e-29 4G27-B nrPDB 118 4e-27 1ORQ-C nrPDB 115 4e-26 1QX7-D nrPDB 99 4e-21 Sequences not found previously or not previously below threshold: 3PJS-K nrPDB 117 1e-26 5EC2-C nrPDB 102 4e-22 2NLJ-C nrPDB 100 2e-21 3FB6-C nrPDB 96 3e-20 2K1E-A nrPDB 88 9e-18 4CHV-A nrPDB 81 9e-16 4H33-A nrPDB 78 9e-15 6CJQ-A nrPDB 56 3e-08 3RBZ-A nrPDB 50 1e-06 1P7B-A nrPDB 49 5e-06 5V4S-A nrPDB 49 6e-06 4XDL-A nrPDB 47 2e-05 2QKS-A nrPDB 47 2e-05 1XL4-A nrPDB 44 1e-04 2Q6A-A nrPDB 44 2e-04 5K7L-A nrPDB 43 3e-04 3VOU-A nrPDB 41 9e-04 3UKM-A nrPDB 41 0.001 6CQ6-A nrPDB 40 0.002 4TWK-A nrPDB 40 0.002 5VA1-A nrPDB 39 0.004 3UM7-A nrPDB 37 0.011 1FPO-A nrPDB 37 0.014 5U6P-A nrPDB 35 0.044 4GX0-A nrPDB 35 0.069 4WD1-A nrPDB 31 1.2 6DNS-A nrPDB 30 2.8 6DLH-A nrPDB 30 2.8 5X1I-A nrPDB 29 5.6 >6CNN-A nrPDB Length = 427 Score = 739 bits (1908), Expect = 0.0, Method: Composition-based stats. Identities = 427/427 (100%), Positives = 427/427 (100%) Query: 1 MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL 60 MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL Sbjct: 1 MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL 60 Query: 61 VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA 120 VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA Sbjct: 61 VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA 120 Query: 121 PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR 180 PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR Sbjct: 121 PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR 180 Query: 181 SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT 240 SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT Sbjct: 181 SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT 240 Query: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN Sbjct: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 Query: 301 FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK 360 FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK Sbjct: 301 FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK 360 Query: 361 LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP 420 LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP Sbjct: 361 LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP 420 Query: 421 EPSQQSK 427 EPSQQSK Sbjct: 421 EPSQQSK 427 >4JTA-B nrPDB Length = 514 Score = 197 bits (500), Expect = 1e-50, Method: Composition-based stats. Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Query: 205 GRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGK 264 G L+ L +G+ L ++ V + + + D W ++ T+GYGD+VP T+ GK Sbjct: 344 GLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGK 403 Query: 265 IVCLCTGVMGVCCTALLVAVVARKLE-FNKAEKHVHNFMMDIQYTKEMKESAARVLQEAW 323 IV + GV AL V V+ F E +Q T K ++ L+++ Sbjct: 404 IVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSSPKIPSSPDLKKS- 462 Query: 324 MFYKHTRRKESHAARRHQRKLLAAIN----AFRQVRLKHRKLREQVNSMVDISKM 374 R S ++ ++ +N FR+ LK + V+I+KM Sbjct: 463 -------RSASTISKSDYMEIQEGVNNSNEDFREENLKTANSTLANTNYVNITKM 510 >2A79-B nrPDB Length = 499 Score = 194 bits (492), Expect = 8e-50, Method: Composition-based stats. Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Query: 205 GRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGK 264 G L+ L +G+ L ++ V + + + D W ++ T+GYGD+VP T+ GK Sbjct: 329 GLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGK 388 Query: 265 IVCLCTGVMGVCCTALLVAVVARKLE-FNKAEKHVHNFMMDIQYTKEMKESAARVLQEAW 323 IV + GV AL V V+ F E +Q T K ++ L+++ Sbjct: 389 IVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKS- 447 Query: 324 MFYKHTRRKESHAARRHQRKLLAAIN----AFRQVRLKHRKLREQVNSMVDISKM 374 R S ++ ++ +N FR+ LK + V+I+KM Sbjct: 448 -------RSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKM 495 >5VMS-A nrPDB Length = 548 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 43/172 (25%), Positives = 78/172 (45%), Gaps = 28/172 (16%) Query: 173 VLLNASYRSIGALNQVRFRH-------WFVAKLYMNTHPGRLLLGLTLGLW--LTTAWVL 223 V ++ R I L +R H W + + H L+ L +G + +++ + Sbjct: 146 VFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFV 205 Query: 224 SVAERQAVNATG-----HLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCT 278 +AE+ A++++G +D LW +T TIGYGD VP T GK + C V + Sbjct: 206 YLAEKDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFF 265 Query: 279 ALLVAVVAR----KLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFY 326 AL ++ K++ + +KH + +++ +AA ++Q AW Y Sbjct: 266 ALPAGILGSGFALKVQQKQRQKH---------FNRQI-PAAASLIQTAWRCY 307 >1F6G-A nrPDB Length = 160 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A LW T T+GYGD+ P T+WG+ V Sbjct: 33 TVLLVIVLLAGSYLAVLAERGAPGAQLITYPAALWWSVETATTVGYGDLYPVTLWGRCVA 92 Query: 268 LCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQE 321 + V G+ L+ A +A + E+ H + +E R L E Sbjct: 93 VVVMVAGITSFGLVTAALATWFVGREQERRGHFVRHSEKAAEEAYTRTTRALHE 146 >3EFF-K nrPDB Length = 139 Score = 131 bits (330), Expect = 5e-31, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A LW T T+GYGD+ P T+WG++V Sbjct: 12 TVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWSVETATTVGYGDLYPVTLWGRLVA 71 Query: 268 LCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQE 321 + V G+ L+ A +A + E+ H + +E R L E Sbjct: 72 VVVMVAGITSFGLVTAALATWFVGREQERRGHFVRHSEKAAEEAYTRTTRALHE 125 >2A9H-A nrPDB Length = 155 Score = 124 bits (311), Expect = 8e-29, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 1/100 (1%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A D LW T T+GYGD+ P T+WG+ V Sbjct: 56 TVLLVIVLLAGSYLAVLAERGAPGAALISYPDALWWSVETATTVGYGDLYPVTLWGRCVA 115 Query: 268 LCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQY 307 + V G+ L+ A VA + E+ H + Sbjct: 116 VVVMVAGITSYGLVFAAVATWFVGREQERRGHFVRHSEKA 155 >4G27-B nrPDB Length = 102 Score = 118 bits (296), Expect = 4e-27, Method: Composition-based stats. Identities = 50/95 (52%), Positives = 69/95 (72%), Gaps = 3/95 (3%) Query: 285 VARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQ 341 + RKLE KAEKHVHNFMMD Q TK +K +AA VL+E W+ YK+T+ +K HA R+HQ Sbjct: 1 MGRKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQ 60 Query: 342 RKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHM 376 RK L AI+ R V+++ RKL +Q N++VD++K + Sbjct: 61 RKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQL 95 >3PJS-K nrPDB Length = 166 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A LW T T+GYGD+ P T+WG++V Sbjct: 39 TVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWSVETATTVGYGDLYPVTLWGRLVA 98 Query: 268 LCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQE 321 + V G+ L+ A +A + ++ + +E R L E Sbjct: 99 VVVMVAGITSFGLVTAALATWFVGQEQQQQQQFVRHSEKAAEEAYTRTTRALHE 152 >1ORQ-C nrPDB Length = 223 Score = 115 bits (288), Expect = 4e-26, Method: Composition-based stats. Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 16/108 (14%) Query: 184 ALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLW 242 A +++RF H F G ++L + G A+ + + E N++ + D LW Sbjct: 127 AADKIRFYHLF----------GAVMLTVLYG-----AFAIYIVEYPDPNSSIKSVFDALW 171 Query: 243 LIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLE 290 +T T+GYGDVVP T GK++ + + G+ LL+ V+ + Sbjct: 172 WAVVTATTVGYGDVVPATPIGKVIGIAVMLTGISALTLLIGTVSNMFQ 219 >5EC2-C nrPDB Length = 125 Score = 102 bits (253), Expect = 4e-22, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 1/93 (1%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A LW T T YGD+ P T+WG++V Sbjct: 33 TVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWACETATTXAYGDLCPVTLWGRLVA 92 Query: 268 LCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300 + V G+ L+ A +A + E+ H Sbjct: 93 VVVMVAGITSFGLVTAALATWFVGREQERRGHF 125 >2NLJ-C nrPDB Length = 124 Score = 99.8 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A LW T T+GYGD+ P T+WG+ V Sbjct: 33 TVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWSVETATTVGYGDLYPVTLWGRCVA 92 Query: 268 LCTGVMGVCCTALLVAVVARKLEFNKAEKHVH 299 + V G+ L+ A +A + E+ H Sbjct: 93 VVVVVAGITSFGLVTAALATWFVGREQERRGH 124 >1QX7-D nrPDB Length = 85 Score = 98.6 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 37/78 (47%), Positives = 55/78 (70%), Gaps = 3/78 (3%) Query: 302 MMDIQYTKEMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQRKLLAAINAFRQVRLKH 358 MMD Q TK +K +AA VL+E W+ YK+T+ +K HA R+HQRK L AI+ R V+++ Sbjct: 1 MMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQ 60 Query: 359 RKLREQVNSMVDISKMHM 376 RKL +Q N++VD++K + Sbjct: 61 RKLNDQANTLVDLAKTQL 78 >3FB6-C nrPDB Length = 104 Score = 95.5 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 1/83 (1%) Query: 209 LGLTLGLWLTTAWVLSVAERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVC 267 L + + L +++ +AER A A LW T T+GYGD+ P T+WG+ V Sbjct: 13 TVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWSVETATTVGYGDLYPVTLWGRCVA 72 Query: 268 LCTGVMGVCCTALLVAVVARKLE 290 + V G+ L+ A +A Sbjct: 73 VVVMVAGITSFGLVTAALATWFV 95 >2K1E-A nrPDB Length = 103 Score = 87.8 bits (216), Expect = 9e-18, Method: Composition-based stats. Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%) Query: 226 AERQAVNAT-GHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAV 284 AER A A D +W T T+GYGD P T G+ V G+ AL+ A Sbjct: 29 AERGAPGAALISYPDAIWWSVETATTVGYGDRYPVTEEGRKVAEQVMKAGIEVFALVTAA 88 Query: 285 VARKLEFNKAEKHVH 299 +A + E+ H Sbjct: 89 LATDFVRREEERRGH 103 >4CHV-A nrPDB Length = 361 Score = 80.9 bits (198), Expect = 9e-16, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 55/154 (35%), Gaps = 6/154 (3%) Query: 162 LVPRAVLLRSGVLLNASYRSIGALNQVRFRHWF--VAKLYMNTHPGRLLLGLTLGLWLTT 219 LVP A L G + Y ++ L +R +F + ++ N + + G+ L Sbjct: 83 LVPLAAFLLDGSPDWSLYCAVWLLKPLRDSTFFPVLGRVLANEARNLIGVTTLFGVVLFA 142 Query: 220 -AWVLSVAERQ-AVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCC 277 A V ER G + +W +T T GYGD +P + G+++ + G+ Sbjct: 143 VALAAYVIERDIQPEKFGSIPQAMWWAVVTLSTTGYGDTIPQSFAGRVLAGAVMMSGIGI 202 Query: 278 TALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEM 311 L ++A + + Sbjct: 203 FGLWAGILATGF--YQEVRRGDFVRNWQLVAAVP 234 >4H33-A nrPDB Length = 137 Score = 77.8 bits (190), Expect = 9e-15, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 28/58 (48%) Query: 236 HLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNK 293 + D LW +T T+GYGD+VP T G+I+ + G+ ++ + + K Sbjct: 43 NYPDALWWAIVTATTVGYGDIVPVTPIGRILASIMMLFGIAFIGMITSTITNFFRCKK 100 >6CJQ-A nrPDB Length = 456 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 49/134 (36%), Gaps = 5/134 (3%) Query: 198 LYMNTHPGRLLLGLTLGLWLTTAWVLSVA----ERQAVNATGH-LSDTLWLIPITFLTIG 252 L +P L L +G L A ++ + + N G + T TIG Sbjct: 145 LSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLSAFYWTITTLTTIG 204 Query: 253 YGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMK 312 YGD+ P T + + ++G L++ +A + A K +H ++ Sbjct: 205 YGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLVSKLDAAKLLHRERVERVTAFLSY 264 Query: 313 ESAARVLQEAWMFY 326 + + LQ + Y Sbjct: 265 KRISPELQRRIIEY 278 >3RBZ-A nrPDB Length = 340 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 6/93 (6%) Query: 204 PGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWG 263 P +L L L + + E + + +L+ +T T+GYGD P T G Sbjct: 19 PATRILLLVLAVIIYGTAGFHFIEGE------SWTVSLYWTFVTIATVGYGDYSPSTPLG 72 Query: 264 KIVCLCTGVMGVCCTALLVAVVARKLEFNKAEK 296 + V+G+ A+ VA + L + K Sbjct: 73 MYFTVTLIVLGIATFAVAVARLLTFLINREQMK 105 >1P7B-A nrPDB Length = 333 Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 50/148 (33%), Gaps = 16/148 (10%) Query: 220 AWVLSVAERQAVNATG-HLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCT 278 A + + + N + + T T+GYGD+ P T++ + +G+ Sbjct: 79 ALLYQLGDAPIANQSPPGFVGAFFFSVETLATVGYGDMHPQTVYAHAIATLEIFVGMSGI 138 Query: 279 ALLVAVVARKLE--------FNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTR 330 AL +V + A N M + + V+ EA + R Sbjct: 139 ALSTGLVFARFARPRAKIMFARHAIVRPFNGRMTLMV--RAANARQNVIAEARAKMRLMR 196 Query: 331 RKESHAARRHQRKLLAAINAFRQVRLKH 358 R+ S L I+ + VR +H Sbjct: 197 REHSSEGYS-----LMKIHDLKLVRNEH 219 >5V4S-A nrPDB Length = 465 Score = 48.5 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 34/98 (34%), Gaps = 6/98 (6%) Query: 198 LYMNTHPGRLLLGLT------LGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTI 251 L PG L L L + W W+ L+ T T+ Sbjct: 169 LAFQPTPGILRLVLFAFWATLVAHWCAVGWLYVDDLLDYQTGWSEYIIALYWTVATIATV 228 Query: 252 GYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 GYGD+ P T +I + ++G A ++ +A L Sbjct: 229 GYGDITPSTDSQRIYTIFVMILGAGVYATVIGNIASIL 266 >4XDL-A nrPDB Length = 282 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 6/130 (4%) Query: 161 YLVPRAVLLRS-GVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTT 219 YLV ++ R+ +S ++ AL + F + ++ P L + L Sbjct: 22 YLVTGGLVFRALEQPFESSQKNTIALEKAEF-----LRDHVCVSPQELETLIQHALDADN 76 Query: 220 AWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTA 279 A V + ++ L + TIGYG++ P T GKI C+ + G+ Sbjct: 77 AGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFG 136 Query: 280 LLVAVVARKL 289 L+A + +L Sbjct: 137 FLLAGIGDQL 146 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 30/68 (44%), Gaps = 7/68 (10%) Query: 239 DTLWLIPITFLTIGYGDVVPG-------TMWGKIVCLCTGVMGVCCTALLVAVVARKLEF 291 ++++ + +T T+G+GD V G W K + ++G+ A +++++ L Sbjct: 205 ESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRV 264 Query: 292 NKAEKHVH 299 + Sbjct: 265 LSKKTKEE 272 >2QKS-A nrPDB Length = 321 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 34/106 (32%), Gaps = 3/106 (2%) Query: 208 LLGLTLGLWLTTAWVLSVAERQAVNATGH-LSDTLWLIPITFLTIGYGDVVPGTMWGKIV 266 L L L L A + + N + T T+GYGD+ P T++ + Sbjct: 49 LAVLFLLLNTAFATLYMLGSAPIANQFPAGFGGAFFFSVETLATVGYGDMHPQTVYAHWI 108 Query: 267 CLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMK 312 +G+ AL K+ K K M M+ Sbjct: 109 ATLEIFVGMSSIALATGCAFIKMSQPK--KRAETLMFSEHAVISMR 152 >1XL4-A nrPDB Length = 301 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 36/91 (39%), Gaps = 11/91 (12%) Query: 207 LLLGLTLGLWLTTAWVLSVA--------ERQAVNATGHLSDTLWLIPITFLTIGYGDVVP 258 + + L GL+L T + ++A E G +D + T TIGYG ++P Sbjct: 48 VFITLITGLYLVTNALFALAYLACGDVIENARP---GSFTDAFFFSVQTMATIGYGKLIP 104 Query: 259 GTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 + + G+ A+ +++ + Sbjct: 105 IGPLANTLVTLEALCGMLGLAVAASLIYARF 135 >2Q6A-A nrPDB Length = 114 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Query: 206 RLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKI 265 ++L LT+ ++ S E D L+ +T T+G G+ P T +GKI Sbjct: 25 QVLFVLTILTLISGTIFYSTVEGLRP------IDALYFSVVTLTTVGEGNFSPQTDFGKI 78 Query: 266 VCLCTGVMGVCCTALLVAVV 285 + +G+ L+ + Sbjct: 79 FTILYIFIGI---GLVFGFI 95 >5K7L-A nrPDB Length = 857 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 31/77 (40%) Query: 228 RQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVAR 287 + +L+ + ++G+G++ P T KI + ++G A + V Sbjct: 414 EGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTT 473 Query: 288 KLEFNKAEKHVHNFMMD 304 + A + ++ M++ Sbjct: 474 IFQQMYANTNRYHEMLN 490 >3VOU-A nrPDB Length = 148 Score = 41.2 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 9/80 (11%) Query: 206 RLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKI 265 ++L LT + S E D L+ +T T+G G+ P T +GK+ Sbjct: 28 QVLFVLTFLTLTSGTIFYSTVEGLRP------LDALYFSVVTLTTVGDGNFSPQTDFGKV 81 Query: 266 VCLCTGVMGVCCTALLVAVV 285 + +G+ L+ + Sbjct: 82 FTILYIFIGI---GLVFGFI 98 >3UKM-A nrPDB Length = 280 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Query: 212 TLGLWL-TTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCT 270 LG L + + +SV + + N + L+ T GYG VP + GK C+ Sbjct: 68 FLGRVLEASNYGVSVLSQASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIY 127 Query: 271 GVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEM 311 V+G+ T L + V +++ + + V F + ++K++ Sbjct: 128 SVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQV 168 Score = 29.3 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 41/106 (38%), Gaps = 8/106 (7%) Query: 188 VRFRH--WFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIP 245 V + H W +K + LL +T+ + + N ++ + Sbjct: 155 VLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWN----FLESFYFCF 210 Query: 246 ITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEF 291 I+ TIG GD VPG + + + G+ C LL+ ++A + Sbjct: 211 ISLSTIGLGDYVPGEGYNQKFRELYKI-GITCY-LLLGLIAMLVVL 254 >6CQ6-A nrPDB Length = 312 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 26/50 (52%) Query: 240 TLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 + + TIG+G++ P T GKI C+ ++G+ L+A V +L Sbjct: 113 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQL 162 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 37/93 (39%), Gaps = 9/93 (9%) Query: 236 HLSDTLWLIPITFLTIGYGDVVPGTM------WGKIVCLCTGVMGVCCTALLVAVVARKL 289 D ++ + IT TIG+GD V G + K V ++G+ A +++++ L Sbjct: 218 SALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWL 277 Query: 290 E---FNKAEKHVHNFMMDIQYTKEMKESAARVL 319 E ++T + ++ VL Sbjct: 278 RVIAKKTKEAVGEFRAHAAEWTANVTSNSLEVL 310 >4TWK-A nrPDB Length = 283 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 26/50 (52%) Query: 240 TLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKL 289 + + TIG+G++ P T GKI C+ ++G+ L+A V +L Sbjct: 108 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQL 157 Score = 31.2 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 236 HLSDTLWLIPITFLTIGYGDVVPGTM------WGKIVCLCTGVMGVCCTALLVAVVARKL 289 D ++ + IT TIG+GD V G + K V ++G+ A +++++ L Sbjct: 213 SALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWL 272 Query: 290 EFNKAE 295 AE Sbjct: 273 RVISAE 278 >5VA1-A nrPDB Length = 795 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 38/103 (36%), Gaps = 8/103 (7%) Query: 229 QAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARK 288 + L+ + ++G+G+V P T KI +C ++G A + V+ Sbjct: 363 GGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAI 422 Query: 289 LE--------FNKAEKHVHNFMMDIQYTKEMKESAARVLQEAW 323 ++ ++ V F+ Q +++ Q AW Sbjct: 423 IQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAW 465 >3UM7-A nrPDB Length = 309 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%) Query: 240 TLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVH 299 + TIGYG+V T G++ C+ ++G+ +L+A V +L + H Sbjct: 119 AFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRHGIGH 178 Query: 300 NFMMDIQ 306 + ++ Sbjct: 179 IEAIFLK 185 Score = 35.4 bits (80), Expect = 0.041, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 54/156 (34%), Gaps = 15/156 (9%) Query: 163 VPRAVLLRSGV--LLNASYR-SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTT 219 +P +L +GV L +S R IG + + F W V + +L L +G L Sbjct: 154 IPLFGILLAGVGDRLGSSLRHGIGHIEAI-FLKWHVPPELVRVLSA--MLFLLIGCLLFV 210 Query: 220 AWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPG------TMWGKIVCLCTGVM 273 V + ++ + +T T+G+GD V G + + + ++ Sbjct: 211 LTPTFVFCYMEDWSKLE---AIYFVIVTLTTVGFGDYVAGADPRQDSPAYQPLVWFWILL 267 Query: 274 GVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTK 309 G+ A ++ + L + Q Sbjct: 268 GLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQSNS 303 >1FPO-A nrPDB Length = 171 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 17/134 (12%), Positives = 52/134 (38%), Gaps = 6/134 (4%) Query: 270 TGVMGVCC-TALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKH 328 + G+ L ++ + + + + H F Q + + + +AW +H Sbjct: 4 FTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRH 63 Query: 329 TRRKESHAARRHQRKLLAAINAFRQ-----VRLKHRKLREQVNSMVDISKMHMILYDLQQ 383 + + H L + + R +L+ R+ +++ D +++ + +++ Sbjct: 64 PLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKK 123 Query: 384 NLSSSHRALEKQID 397 + H+ + +Q+D Sbjct: 124 MFDTRHQLMVEQLD 137 >5U6P-A nrPDB Length = 660 Score = 35.4 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 45/130 (34%), Gaps = 2/130 (1%) Query: 188 VRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPIT 247 VR + L + G L + L +S+ E + S L+ Sbjct: 296 VRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSH 355 Query: 248 FLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEF--NKAEKHVHNFMMDI 305 L IGYG P +M + + + ++G C A+ V ++ + ++ + Sbjct: 356 MLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVE 415 Query: 306 QYTKEMKESA 315 QY K A Sbjct: 416 QYMSFHKLPA 425 >4GX0-A nrPDB Length = 565 Score = 35.1 bits (79), Expect = 0.069, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 23/74 (31%), Gaps = 1/74 (1%) Query: 210 GLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLC 269 L + L + + ++ T+G+GD+ + G + Sbjct: 26 FLLVMLLAYASIFRYLM-WHLEGRAYSFMAGIYWTITVMTTLGFGDITFESDAGYLFASI 84 Query: 270 TGVMGVCCTALLVA 283 V GV +++ Sbjct: 85 VTVSGVIFLDIILP 98 >4WD1-A nrPDB Length = 658 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 20/98 (20%) Query: 47 LWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVA------L 100 W+ W ++ FLV ++ +T +L F A + Q WR+A L Sbjct: 310 FWYTSTGWMMWNFLVSGLLTGTTIVLYDGSPGFPATDAQ----------WRIAERTGATL 359 Query: 101 TGRQAAQIVLELVVCGLHPA---PVRGPPCVQDLGAPL 135 G AA V+ G+HPA + CV G+PL Sbjct: 360 FGTSAA-YVMACRKAGVHPARDLDLSAIQCVATTGSPL 396 >6DNS-A nrPDB Length = 623 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Query: 70 FLLLCLIVAFHAKEVQLFMTDNGLR-DW 96 FL+ CLI+ FH E Q+ + GLR +W Sbjct: 14 FLMACLIITFHKVEAQVPDPNQGLRAEW 41 >6DLH-A nrPDB Length = 734 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Query: 70 FLLLCLIVAFHAKEVQLFMTDNGLR-DW 96 FL+ CLI+ FH E Q+ + GLR +W Sbjct: 14 FLMACLIITFHKVEAQVPDPNQGLRAEW 41 >5X1I-A nrPDB Length = 474 Score = 28.5 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 27/86 (31%), Gaps = 3/86 (3%) Query: 257 VPGTMWGKIVC--LCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKES 314 VP T +G ++ + + + A A L A+ +N + + Sbjct: 98 VPVTPYGHVIGDGIIFYLAEEEFVYVGRAPAANWL-MYHAQTGGYNVDIVHDDRSPSRPM 156 Query: 315 AARVLQEAWMFYKHTRRKESHAARRH 340 V + +W F + + H Sbjct: 157 GKPVQRISWRFQIQGPKAWDVIEKLH 182 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.321 0.132 0.376 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,485,343 Number of Sequences: 36641 Number of extensions: 580176 Number of successful extensions: 1977 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 65 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 1876 Number of HSP's gapped (non-prelim): 92 length of query: 427 length of database: 10,336,785 effective HSP length: 100 effective length of query: 327 effective length of database: 6,672,685 effective search space: 2181967995 effective search space used: 2181967995 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 60 (27.7 bits)