BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O15382 (392 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5BWR-A nrPDB 753 0.0 2COJ-A nrPDB 460 e-130 5U3F-A nrPDB 233 7e-62 3DTG-A nrPDB 222 2e-58 4DQN-A nrPDB 153 1e-37 3UYY-A nrPDB 146 2e-35 1IYD-A nrPDB 91 1e-18 4WHX-A nrPDB 88 7e-18 6NST-A nrPDB 70 2e-12 2EJ2-A nrPDB 69 5e-12 5CE8-A nrPDB 65 3e-11 6H65-A nrPDB 62 5e-10 5MQZ-A nrPDB 47 1e-05 5E25-A nrPDB 47 2e-05 4TM5-A nrPDB 35 0.046 3HEM-A nrPDB 29 4.1 2DFV-A nrPDB 28 5.8 2F00-A nrPDB 28 6.4 3GFB-A nrPDB 28 9.0 >5BWR-A nrPDB Length = 369 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/365 (100%), Positives = 365/365 (100%) Query: 28 ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLT 87 ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLT Sbjct: 5 ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLT 64 Query: 88 LHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLEC 147 LHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLEC Sbjct: 65 LHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLEC 124 Query: 148 IRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVT 207 IRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVT Sbjct: 125 IRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVT 184 Query: 208 PVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGT 267 PVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGT Sbjct: 185 PVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGT 244 Query: 268 MNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL 327 MNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL Sbjct: 245 MNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL 304 Query: 328 EEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHE 387 EEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHE Sbjct: 305 EEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHE 364 Query: 388 WMFPV 392 WMFPV Sbjct: 365 WMFPV 369 >2COJ-A nrPDB Length = 386 Score = 460 bits (1183), Expect = e-130, Method: Compositional matrix adjust. Identities = 215/367 (58%), Positives = 273/367 (74%), Gaps = 2/367 (0%) Query: 23 GPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQ 81 G + +FKA DL + +KP P LVFG FTDHML VEW+ + GW +P I+ Sbjct: 16 GGSKEVVGTFKAKDLIVTPATILKEKPDPNN-LVFGTVFTDHMLTVEWSSEFGWEKPHIK 74 Query: 82 PFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDK 141 P QNL+LHP SS+LHY+++LFEG+KAF+G D ++RLF+P LNMDRM RSA+R LP FDK Sbjct: 75 PLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDK 134 Query: 142 LELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYF 201 ELLECI++L+++D++WVP + SLY+RP IG EPSLGV +PT+ALLFV+L PVG YF Sbjct: 135 EELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYF 194 Query: 202 PGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQ 261 G+ PVSL A+P ++RAW GG G+ K+GGNYG ++ Q EA+ GC+QVLWLYG DHQ Sbjct: 195 SSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQ 254 Query: 262 LTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMK 321 +TEVGTMN+F+YW +EDG EL TPPL+G+ILPGV R+ +LD+A WGEF+V ER +TM Sbjct: 255 ITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMD 314 Query: 322 QLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQY 381 L ALE RVRE+FGSGTAC VCPV ILYK +HIPTMENGP+L R +L +IQY Sbjct: 315 DLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQY 374 Query: 382 GIRAHEW 388 G +W Sbjct: 375 GREERDW 381 >5U3F-A nrPDB Length = 368 Score = 233 bits (595), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 132/338 (39%), Positives = 189/338 (55%), Gaps = 9/338 (2%) Query: 57 FGKTFTDHMLMVEWND-KGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQV 115 FGK TDHM+ +++ + +GW R+ P+ + L P++ LHY+ ++FEG+KA++ D + Sbjct: 31 FGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSI 90 Query: 116 RLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAG-TSLYVRPVLI 174 FR N R+ SA RL +P +E +R+LI VDK WVP A G +LY+RP + Sbjct: 91 VSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLRPFIF 150 Query: 175 GNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNY 234 EP LGV T+ +I P GAYF GG + PVS+ ++RA GG G K GGNY Sbjct: 151 ATEPGLGVRPATQYRYLLIASPAGAYFKGG-IAPVSVWVSTEYVRACPGGTGAAKFGGNY 209 Query: 235 GPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTHEDGVLELVTPPLNGVIL 293 ++L Q EA + GC+QV+WL + + + E+G MNIF + G LVTP L+G +L Sbjct: 210 AASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF-FVLGSGGSARLVTPELSGSLL 268 Query: 294 PGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYK 353 PG+ R SLL +A G F V ER I + + + G + EVF GTA + PV R+ + Sbjct: 269 PGITRDSLLQLAIDAG-FAVEERRIDIDEWQKKAAAGEITEVFACGTAAVITPVARVRHG 327 Query: 354 DRNLHIPTMENGPELILRFQKELKEIQYGIRA--HEWM 389 I + G E+ + + L IQ G A H WM Sbjct: 328 ASEFRIADGQPG-EVTMALRDTLTGIQRGTFADTHGWM 364 >3DTG-A nrPDB Length = 372 Score = 222 bits (565), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 131/338 (38%), Positives = 190/338 (56%), Gaps = 9/338 (2%) Query: 57 FGKTFTDHMLMVEWN-DKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQV 115 FGK +TDHM+ +++ D+GW ++ P+ + L P++ LHY ++FEG+KA++ D + Sbjct: 35 FGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQEIFEGLKAYRWADGSI 94 Query: 116 RLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAG-TSLYVRPVLI 174 FRP N R+ SA RL +P + +E +R+LI VD+ WVP A G SLY+RP +I Sbjct: 95 VSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEESLYLRPFVI 154 Query: 175 GNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNY 234 EP LGV +I P GAYF GG + PVS+ ++RA GG G K GGNY Sbjct: 155 ATEPGLGVRPSNEYRYLLIASPAGAYFKGG-IKPVSVWLSHEYVRASPGGTGAAKFGGNY 213 Query: 235 GPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTHEDGVLELVTPPLNGVIL 293 ++L Q +A + GC+QV+WL + + + E+G MN+F + G LVTP L+G +L Sbjct: 214 AASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVFG-SGGSARLVTPELSGSLL 272 Query: 294 PGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYK 353 PG+ R SLL +A G F V ER I + + + G + EVF GTA + PV + + Sbjct: 273 PGITRDSLLQLATDAG-FAVEERKIDVDEWQKKAGAGEITEVFACGTAAVITPVSHVKHH 331 Query: 354 DRNLHIPTMENGPELILRFQKELKEIQYGIRA--HEWM 389 D I + G E+ + + L IQ G A H WM Sbjct: 332 DGEFTIADGQPG-EITMALRDTLTGIQRGTFADTHGWM 368 >4DQN-A nrPDB Length = 345 Score = 153 bits (387), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 101/329 (30%), Positives = 172/329 (52%), Gaps = 20/329 (6%) Query: 70 WNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLR 129 + D W ++ L + +S +LHY + FEG+KA++ KD V+LFRP +N +R+ R Sbjct: 29 YKDGKWDDGKLTEDATLHISESSPALHYGQEAFEGLKAYRTKDGSVQLFRPNMNAERLQR 88 Query: 130 SAMRLCLPSFDKLELLECIRRLIEVDKDWVPD-AAGTSLYVRPVLIGNEPSLGVSQPTRA 188 +A RL +P + ++ ++++ ++++VP G +LY+RP+LIG +GV Sbjct: 89 TADRLLMPQVPTDKFIDAAKQVVRANEEYVPPYGTGATLYLRPLLIGVGDVIGVHPADEY 148 Query: 189 LLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRG 248 + + PVG YF GG + P + L + RA G G K+GGNY ++L + A +R Sbjct: 149 IFTIFAMPVGNYFKGG-LAPTNFLIQDDYDRAAPHGTGAAKVGGNYAASLLPGKVAHERQ 207 Query: 249 CEQVLWLYGPDH-QLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQT 307 V++L H ++ EVG+ N F E +T PL+ ILP V + SLL +A+ Sbjct: 208 FSDVIYLDPATHTKIEEVGSANFFGITKDN----EFIT-PLSPSILPSVTKYSLLYLAEH 262 Query: 308 WGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHI--PTMENG 365 + +E + + +L + +E G GTA + P+ + + D + H+ E G Sbjct: 263 RFGMKAIEGDVCVDELDKFVEAG------ACGTAAVISPIGGVQHGD-DFHVFYSETEVG 315 Query: 366 PELILRFQKELKEIQYG-IRAHE-WMFPV 392 P + + EL IQ+G ++A E W++ V Sbjct: 316 P-VTHKLYDELTGIQFGDVKAPEGWIYKV 343 >3UYY-A nrPDB Length = 358 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 106/333 (31%), Positives = 159/333 (47%), Gaps = 16/333 (4%) Query: 55 LVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQ 114 L F TD + W D W + + L S++LHY Q FEG+KA++ D Sbjct: 29 LGFSYIRTDLRYLAHWKDGEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYRCADGS 88 Query: 115 VRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPD-AAGTSLYVRPVL 173 + LFRP N RM S RL +P + ++ +++ ++ ++P G SLY+RP + Sbjct: 89 INLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLYLRPFV 148 Query: 174 IGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGN 233 IG ++GV + V PVG YF GG +TP + + + RA G G K+GGN Sbjct: 149 IGVGDNIGVRTAPEFIFSVFCVPVGPYFKGG-LTPTNFITSD-YDRAAPHGTGAAKVGGN 206 Query: 234 YGPTVLVQQEALKRGCEQVLWLYGPDH-QLTEVGTMNIFVYWTHEDGVLELVTPPLNGVI 292 Y ++L EA KR V++L H + E G N F +DG + VTP + I Sbjct: 207 YAASLLPGYEAKKRDFADVIYLDPATHTTIEEAGAANFFA--ITQDG-QKFVTPQ-SPSI 262 Query: 293 LPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILY 352 LP + + SLL +A+ V E I + +L G+ E GTA + P+ I + Sbjct: 263 LPSITKYSLLWLAEHRLGLEVEEGDIRIDEL------GKFSEAGACGTAAVITPIGGIQH 316 Query: 353 KDRNLHIPTMENGP-ELILRFQKELKEIQYGIR 384 D + H+ E+ P + R EL IQYG + Sbjct: 317 GD-DFHVFYSESEPGPVTRRLYDELVGIQYGDK 348 >1IYD-A nrPDB Length = 309 Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 80/286 (27%), Positives = 132/286 (46%), Gaps = 31/286 (10%) Query: 72 DKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA 131 D W + +++ +H S +LHY +FEG++ + V +FR +M R+ SA Sbjct: 7 DYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV-VFRHREHMQRLHDSA 65 Query: 132 MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLF 191 P + + I L+E +D + TS Y+RP++ + +GV+ P Sbjct: 66 KIYRFP------VSQSIDELMEACRDVIRKNNLTSAYIRPLIFVGDVGMGVNPPAGYSTD 119 Query: 192 VILCPVGAYFPGGSVTPVSLLAD--PAFIRAWVGGVGNY-----KLGGNYGPTVLVQQEA 244 VI+ A FP G+ L A + +W N K GGNY ++LV EA Sbjct: 120 VII----AAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGSEA 175 Query: 245 LKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDM 304 + G ++ + L + ++E N+F +DGVL TPP LPG+ R +++ + Sbjct: 176 RRHGYQEGIAL-DVNGYISEGAGENLFEV---KDGVL--FTPPFTSSALPGITRDAIIKL 229 Query: 305 AQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRI 350 A+ G V E+ ++ + L A EVF SGTA ++ PV + Sbjct: 230 AKELG-IEVREQVLSRESLYLA------DEVFMSGTAAEITPVRSV 268 >4WHX-A nrPDB Length = 311 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 83/291 (28%), Positives = 138/291 (47%), Gaps = 28/291 (9%) Query: 65 MLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNM 124 M M + + K W ++ +++ +H + +LHY + +FEG++A+K D +FR + Sbjct: 5 MSMADRDGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHT 64 Query: 125 DRMLRSA--MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVL-IGNEPSLG 181 R+L SA ++ +P FD+ E LE +R D V + S Y+RP++ IG+E LG Sbjct: 65 KRLLNSAKIFQMDVP-FDQ-ETLEAAQR------DVVRENKLESCYLRPIIWIGSEK-LG 115 Query: 182 VSQPTRALLFVILC-PVGAYFPGGSVTPVSLLADPAFIRAWVG-GVGNYKLGGNYGPTVL 239 VS + I P GAY + + +F R V + K G Y ++L Sbjct: 116 VSAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSIL 175 Query: 240 VQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQ 299 QEA G ++ L L D ++E N F+ +L TP L L G+ R Sbjct: 176 ANQEATADGYDEAL-LLDVDGYVSEGSGENFFLV-----NRGKLYTPDL-ASCLDGITRD 228 Query: 300 SLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRI 350 +++ +A+ G V+E+ IT ++ A E F +GTA +V P+ + Sbjct: 229 TVITLAKEAG-IEVIEKRITRDEVYTA------DEAFFTGTAAEVTPIREL 272 >6NST-A nrPDB Length = 307 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/258 (25%), Positives = 119/258 (46%), Gaps = 27/258 (10%) Query: 97 YSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA--MRLCLPSFDKLELLECIRRLIEV 154 Y + +FEG++A+ Q +FR + DR+ SA M + +P + + E+ E R + Sbjct: 33 YGMGVFEGVRAYD-TPQGTAIFRLQAHTDRLFDSAHIMNMQIP-YSRDEINEATRAAVRE 90 Query: 155 DKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILC-PVGAYFPGGSVTPVSLLA 213 + S Y+RP++ +G+ + +I GAY ++ + Sbjct: 91 NNL-------ESAYIRPMVFYGSEGMGLRASGLKVHVIIAAWSWGAYMGEEALQQGIKVR 143 Query: 214 DPAFIRAWVG-GVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFV 272 +F R V + K G Y ++L QEA+ G ++ + L P+ + E NIF+ Sbjct: 144 TSSFTRHHVNISMTRAKSNGAYINSMLALQEAISGGADEAMML-DPEGYVAEGSGENIFI 202 Query: 273 YWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRV 332 +DGV + TP + L G+ R ++L +A G F++VE+ IT ++ A Sbjct: 203 I---KDGV--IYTPEVTAC-LNGITRNTILTLAAEHG-FKLVEKRITRDEVYIA------ 249 Query: 333 REVFGSGTACQVCPVHRI 350 E F +GTA +V P+ + Sbjct: 250 DEAFFTGTAAEVTPIREV 267 >2EJ2-A nrPDB Length = 308 Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 80/285 (28%), Positives = 129/285 (45%), Gaps = 30/285 (10%) Query: 75 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA--M 132 W P + S +LHY +FEG++A++ +FR ++ R SA + Sbjct: 9 WMNGAFVPQEEAKTSVLSHALHYGTSVFEGIRAYETAKGPA-IFRLKEHVKRFYNSAKVL 67 Query: 133 RLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQ-PTR-ALL 190 R+ +P F EL E I+ ++ + S Y+RP+ +LGV+ P A + Sbjct: 68 RMEIP-FAPEELEEAIKEVVRRN-------GYRSCYIRPLAWMGAKALGVNPLPNNPAEV 119 Query: 191 FVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGV-GNYKLGGNYGPTVLVQQEALKRGC 249 V GAY +V + L ++ R + G K+GGNY + L + EA+ G Sbjct: 120 MVAAWEWGAYLGEEAVRKGARLITSSWARFPANVMPGKAKVGGNYVNSALAKMEAVAAGA 179 Query: 250 EQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWG 309 ++ L L + + E N+F DGV+ + +N L G+ R S++ +A+ G Sbjct: 180 DEAL-LLDEEGYVAEGSGENLFFV---RDGVIYALEHSVN---LEGITRDSVIRIAKDLG 232 Query: 310 -EFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYK 353 E +VV T QL A EVF +GTA +V PV I ++ Sbjct: 233 YEVQVVR--ATRDQLYMA------DEVFMTGTAAEVTPVSMIDWR 269 >5CE8-A nrPDB Length = 307 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 72/285 (25%), Positives = 130/285 (45%), Gaps = 35/285 (12%) Query: 73 KGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAM 132 K W R+ + + S SL+Y +FEG++A+ + + +FR +M+R+LRSA Sbjct: 14 KVWLDGRLVDEEEAKVTVLSPSLNYGFGVFEGIRAY-WNGENLYVFRLRDHMERLLRSAK 72 Query: 133 RLCLPS-FDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVS-QPTRALL 190 + L + EL + + + + LY+RPV ++P + + + +A + Sbjct: 73 IIGLDVPYTAEELSKAVVETVR------ANGFKEDLYIRPVAYISKPQISLDVRGLQASV 126 Query: 191 FVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNY-----KLGGNYGPTVLVQQEAL 245 + P G Y V A + +W + K G Y +++ EA Sbjct: 127 AIAAIPFGKYLKVEGVR--------AAVVSWRRVHTSMMPVMAKATGIYLNSIMAAVEAR 178 Query: 246 KRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMA 305 RG ++ + L + ++ E NIF+ GVL +TPPL IL G+ R++++ +A Sbjct: 179 ARGYDEAIML-NAEGKVVEGSGENIFIV---RRGVL--MTPPLEDGILEGITRETVISIA 232 Query: 306 QTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRI 350 G ++E++IT ++L A E F GTA ++ P+ I Sbjct: 233 GDLG-IPLLEKSITREELYAA------DEAFFVGTAAEITPIIEI 270 >6H65-A nrPDB Length = 317 Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 82/339 (24%), Positives = 144/339 (42%), Gaps = 59/339 (17%) Query: 74 GWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAF-KGKDQQVRLFRPWLNMDRMLRSA- 131 GW + P+ +LH ++ + + LFEG++A+ + +Q+ +FR ++ R+ +SA Sbjct: 16 GWMNGQCIPWDQCSLHVSTQAAFFGASLFEGVRAYWNAEREQLYVFRLDEHLRRLEQSAK 75 Query: 132 ---MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVL-IGNEPS-LGVSQPT 186 M+L +P D + + + R E D LYV I ++P L + T Sbjct: 76 MLRMKLSMPIADIRQGVLELLRANEFRSD-------VHLYVASYFGINHDPDPLFPTDDT 128 Query: 187 RALLFVILCPVGAYFPGGSVTPVSLLAD--PAFIRAWVGGVGN-----YKLGGNYGPTVL 239 G Y G +V+ + L+ A + +W + K+G NY + L Sbjct: 129 -----------GVYVTGTAVSRLPLVHTGISACMSSWRRISDDSVPPRIKIGANYQNSRL 177 Query: 240 VQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQ 299 Q EA G + L G + V DG +++PP+ IL V R+ Sbjct: 178 AQTEARVNGYHTSVLLNSRGKVSETPGACLLMV----RDG--RVISPPVTADILESVTRK 231 Query: 300 SLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHI 359 +L+ +++ + V+ER + +L A EVF GT ++ PV I DR + + Sbjct: 232 TLMSLSEAELDSPVIERDMDRTELYIA------EEVFLCGTIAEILPVTTI---DR-IQV 281 Query: 360 PTMENGPELILRFQKELKEIQYGIRA------HEWMFPV 392 E GP + L+E+ +G+ + W+ PV Sbjct: 282 GDGEVGP-----VTRRLQELYFGVTSGQLEAYKSWLLPV 315 >5MQZ-A nrPDB Length = 290 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 68/257 (26%), Positives = 116/257 (45%), Gaps = 36/257 (14%) Query: 97 YSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIEVD 155 Y +FEG++A+ G R+FR ++DR+ SA + L K E +E I L + Sbjct: 27 YGDGVFEGIRAYNG-----RVFRLKEHIDRLYDSAKAIDLEIPITKEEFMEII--LETLR 79 Query: 156 KDWVPDAAGTSLYVRPVLIGNEPSLGVS--QPTRALLFVILCPVGAYFPGGSVTPVSLLA 213 K+ + DA Y+RP++ LG+ + + VI P G + G + L A Sbjct: 80 KNNLRDA-----YIRPIVTRGIGDLGLDPRKCQNPSIIVITKPWGKLY--GDLYEKGLTA 132 Query: 214 DPAFIR--AWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIF 271 +R ++ N K NY +L + EA +G ++ ++L + ++E NIF Sbjct: 133 ITVAVRRNSFDALPPNIK-SLNYLNNILAKIEANAKGGDEAIFL-DRNGYVSEGSGDNIF 190 Query: 272 VYWTHEDGVLELVTPP-LNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEG 330 V + TPP +N L G+ R++++++ G E I + L A Sbjct: 191 VVKNGA-----ITTPPTINN--LRGITREAVIEIINRLG-IPFKETNIGLYDLYTA---- 238 Query: 331 RVREVFGSGTACQVCPV 347 EVF +GTA ++ P+ Sbjct: 239 --DEVFVTGTAAEIAPI 253 >5E25-A nrPDB Length = 291 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 70/263 (26%), Positives = 120/263 (45%), Gaps = 42/263 (15%) Query: 97 YSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA--MRLCLPSFDKLELLECIRRLIEV 154 Y +FEG++A+ GK +F+ + ++DR+ A + L +P K E E I L + Sbjct: 28 YGDGVFEGIRAYNGK-----VFKLYEHIDRLYDCARVIDLKIP-LSKEEFAEAI--LETL 79 Query: 155 DKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRA---LLFVILCPVGAYFPGGSVTPVSL 211 ++ + DA Y+RP++ LG+ P + + +I P G + G + L Sbjct: 80 RRNNLRDA-----YIRPIVTRGAGDLGL-DPRKCPSPNVIIITKPWGKLY--GDLYEKGL 131 Query: 212 LADPAFIR-AWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQ--LTEVGTM 268 A IR + + NY +L + EA +G ++ ++L DH ++E Sbjct: 132 KAITVAIRRNAIDSLPPNIKSLNYLNNILAKIEANAKGGDEAIFL---DHNGYISEGSGD 188 Query: 269 NIFVYWTHEDGVLELVTPP-LNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL 327 NIF+ ++G + TPP LN L G+ RQ ++++ E E I + L A Sbjct: 189 NIFIV---KNGTI--TTPPTLNN--LKGITRQVVIELINEL-EIPFREANIGLFDLYSA- 239 Query: 328 EEGRVREVFGSGTACQVCPVHRI 350 E+F +GTA ++ PV I Sbjct: 240 -----DEIFVTGTAAEIAPVTYI 257 >4TM5-A nrPDB Length = 311 Score = 35.4 bits (80), Expect = 0.046, Method: Compositional matrix adjust. Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 38/210 (18%) Query: 161 DAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVI--LCPVGAYFPGGSVTPVSLLADP--- 215 D AG V ++ N +LG Q + V + G FP +V V +A P Sbjct: 88 DEAGWRALVARLVDANAAALGDGQHAIVYIQVTRGVAKRGHAFPANAVPTVFAMASPLAL 147 Query: 216 --------------AFIRAWVG-GVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDH 260 A R W+ + + L GN VL+ Q A + + + L D Sbjct: 148 PTDAQRAQGVHCVTAEDRRWLHCDIKSVSLLGN----VLMAQHAAEHDAAETIQLR--DG 201 Query: 261 QLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITM 320 +TE + N+ W ++G EL+ PP + IL G+ + ++A+ G R V R I Sbjct: 202 NVTEGSSSNV---WIVKNG--ELIAPPRSNRILEGIRYALVEELAEECG-IRFVAREINE 255 Query: 321 KQLLRALEEGRVREVFGSGTACQVCPVHRI 350 + LRA + E+ + ++ PV R+ Sbjct: 256 AE-LRAAD-----EILLTSATKEILPVTRL 279 >3HEM-A nrPDB Length = 302 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 15/98 (15%) Query: 180 LGVSQPTRALLFV--ILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNY-KLGGNYGP 236 LG++ P L F+ IL + FPGG + +S + + W V Y ++G NY P Sbjct: 195 LGLTSPMSLLRFIKFILTEI---FPGGRLPRISQVDYYSSNAGW--KVERYHRIGANYVP 249 Query: 237 TVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYW 274 T+ +AL+ ++ + L G + T +I++++ Sbjct: 250 TLNAWADALQAHKDEAIALKGQE-------TCDIYMHY 280 >2DFV-A nrPDB Length = 347 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 40 EMTQKPHKKPGPGEPL--VFGKTFTDHMLMV-EWNDKGWGQPRIQPFQ 84 E+ + KPGPGE L V + L + EWN+ W Q RI+P Q Sbjct: 17 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNE--WAQSRIKPPQ 62 >2F00-A nrPDB Length = 491 Score = 28.1 bits (61), Expect = 6.4, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 21/42 (50%) Query: 136 LPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNE 177 +P D L IR ++D VPD A + + PVL GN+ Sbjct: 417 IPGADSRSLCRTIRGRGKIDPILVPDPARVAEMLAPVLTGND 458 >3GFB-A nrPDB Length = 350 Score = 27.7 bits (60), Expect = 9.0, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 40 EMTQKPHKKPGPGEPL--VFGKTFTDHMLMV-EWNDKGWGQPRIQPFQ 84 E+ + KPGPGE L V + L + EWN+ W Q RI+P Q Sbjct: 18 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNE--WAQSRIKPPQ 63 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5BWR-A nrPDB 521 e-148 2COJ-A nrPDB 495 e-140 5U3F-A nrPDB 403 e-113 3DTG-A nrPDB 394 e-110 3UYY-A nrPDB 372 e-103 4DQN-A nrPDB 352 1e-97 4WHX-A nrPDB 313 1e-85 1IYD-A nrPDB 305 2e-83 2EJ2-A nrPDB 271 4e-73 6H65-A nrPDB 265 3e-71 6NST-A nrPDB 263 7e-71 5CE8-A nrPDB 255 3e-68 5MQZ-A nrPDB 243 1e-64 5E25-A nrPDB 238 2e-63 Sequences not found previously or not previously below threshold: 6GKR-A nrPDB 193 2e-49 1G2W-A nrPDB 118 5e-27 4JXU-A nrPDB 105 2e-23 4PBC-A nrPDB 100 1e-21 4TM5-A nrPDB 98 6e-21 3CSW-A nrPDB 97 1e-20 4UUG-A nrPDB 89 5e-18 2Y4R-A nrPDB 72 4e-13 1ET0-A nrPDB 57 1e-08 3SNO-A nrPDB 57 1e-08 4K6N-A nrPDB 42 6e-04 6CQB-A nrPDB 30 2.0 3E96-A nrPDB 30 2.2 6ED1-A nrPDB 29 2.7 1IW7-A nrPDB 29 3.2 5D1F-A nrPDB 28 6.7 >5BWR-A nrPDB Length = 369 Score = 521 bits (1341), Expect = e-148, Method: Composition-based stats. Identities = 365/369 (98%), Positives = 365/369 (98%) Query: 24 PRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPF 83 ASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPF Sbjct: 1 GSHMASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPF 60 Query: 84 QNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLE 143 QNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLE Sbjct: 61 QNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLE 120 Query: 144 LLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPG 203 LLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPG Sbjct: 121 LLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPG 180 Query: 204 GSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLT 263 GSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLT Sbjct: 181 GSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLT 240 Query: 264 EVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQL 323 EVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQL Sbjct: 241 EVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQL 300 Query: 324 LRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGI 383 LRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGI Sbjct: 301 LRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGI 360 Query: 384 RAHEWMFPV 392 RAHEWMFPV Sbjct: 361 RAHEWMFPV 369 >2COJ-A nrPDB Length = 386 Score = 495 bits (1275), Expect = e-140, Method: Composition-based stats. Identities = 215/367 (58%), Positives = 273/367 (74%), Gaps = 2/367 (0%) Query: 23 GPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQ 81 G + +FKA DL + +KP P LVFG FTDHML VEW+ + GW +P I+ Sbjct: 16 GGSKEVVGTFKAKDLIVTPATILKEKPDPNN-LVFGTVFTDHMLTVEWSSEFGWEKPHIK 74 Query: 82 PFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDK 141 P QNL+LHP SS+LHY+++LFEG+KAF+G D ++RLF+P LNMDRM RSA+R LP FDK Sbjct: 75 PLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDK 134 Query: 142 LELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYF 201 ELLECI++L+++D++WVP + SLY+RP IG EPSLGV +PT+ALLFV+L PVG YF Sbjct: 135 EELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYF 194 Query: 202 PGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQ 261 G+ PVSL A+P ++RAW GG G+ K+GGNYG ++ Q EA+ GC+QVLWLYG DHQ Sbjct: 195 SSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQ 254 Query: 262 LTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMK 321 +TEVGTMN+F+YW +EDG EL TPPL+G+ILPGV R+ +LD+A WGEF+V ER +TM Sbjct: 255 ITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMD 314 Query: 322 QLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQY 381 L ALE RVRE+FGSGTAC VCPV ILYK +HIPTMENGP+L R +L +IQY Sbjct: 315 DLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQY 374 Query: 382 GIRAHEW 388 G +W Sbjct: 375 GREERDW 381 >5U3F-A nrPDB Length = 368 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 134/356 (37%), Positives = 191/356 (53%), Gaps = 10/356 (2%) Query: 39 LEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQPFQNLTLHPASSSLHY 97 + ++ EP FGK TDHM+ +++ + GW R+ P+ + L P++ LHY Sbjct: 14 VNPATDAQRESMLREP-GFGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHY 72 Query: 98 SLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKD 157 + ++FEG+KA++ D + FR N R+ SA RL +P +E +R+LI VDK Sbjct: 73 AQEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKA 132 Query: 158 WVPDAAG-TSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPA 216 WVP A G +LY+RP + EP LGV T+ +I P GAYF GG + PVS+ Sbjct: 133 WVPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG-IAPVSVWVSTE 191 Query: 217 FIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPD-HQLTEVGTMNIFVYWT 275 ++RA GG G K GGNY ++L Q EA + GC+QV+WL + + E+G MNIF Sbjct: 192 YVRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIFFV-L 250 Query: 276 HEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREV 335 G LVTP L+G +LPG+ R SLL +A G F V ER I + + + G + EV Sbjct: 251 GSGGSARLVTPELSGSLLPGITRDSLLQLAIDAG-FAVEERRIDIDEWQKKAAAGEITEV 309 Query: 336 FGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRA--HEWM 389 F GTA + PV R+ + I + G E+ + + L IQ G A H WM Sbjct: 310 FACGTAAVITPVARVRHGASEFRIADGQPG-EVTMALRDTLTGIQRGTFADTHGWM 364 >3DTG-A nrPDB Length = 372 Score = 394 bits (1013), Expect = e-110, Method: Composition-based stats. Identities = 131/339 (38%), Positives = 189/339 (55%), Gaps = 9/339 (2%) Query: 56 VFGKTFTDHMLMVEWN-DKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQ 114 FGK +TDHM+ +++ D+GW ++ P+ + L P++ LHY ++FEG+KA++ D Sbjct: 34 GFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQEIFEGLKAYRWADGS 93 Query: 115 VRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAG-TSLYVRPVL 173 + FRP N R+ SA RL +P + +E +R+LI VD+ WVP A G SLY+RP + Sbjct: 94 IVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEESLYLRPFV 153 Query: 174 IGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGN 233 I EP LGV +I P GAYF GG + PVS+ ++RA GG G K GGN Sbjct: 154 IATEPGLGVRPSNEYRYLLIASPAGAYFKGG-IKPVSVWLSHEYVRASPGGTGAAKFGGN 212 Query: 234 YGPTVLVQQEALKRGCEQVLWLYGPD-HQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVI 292 Y ++L Q +A + GC+QV+WL + + E+G MN+F + G LVTP L+G + Sbjct: 213 YAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVF-GSGGSARLVTPELSGSL 271 Query: 293 LPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILY 352 LPG+ R SLL +A G F V ER I + + + G + EVF GTA + PV + + Sbjct: 272 LPGITRDSLLQLATDAG-FAVEERKIDVDEWQKKAGAGEITEVFACGTAAVITPVSHVKH 330 Query: 353 KDRNLHIPTMENGPELILRFQKELKEIQYGIRA--HEWM 389 D I + G E+ + + L IQ G A H WM Sbjct: 331 HDGEFTIADGQPG-EITMALRDTLTGIQRGTFADTHGWM 368 >3UYY-A nrPDB Length = 358 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 108/343 (31%), Positives = 162/343 (47%), Gaps = 18/343 (5%) Query: 55 LVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQ 114 L F TD + W D W + + L S++LHY Q FEG+KA++ D Sbjct: 29 LGFSYIRTDLRYLAHWKDGEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYRCADGS 88 Query: 115 VRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPD-AAGTSLYVRPVL 173 + LFRP N RM S RL +P + ++ +++ ++ ++P G SLY+RP + Sbjct: 89 INLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLYLRPFV 148 Query: 174 IGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGN 233 IG ++GV + V PVG YF GG +TP + + + RA G G K+GGN Sbjct: 149 IGVGDNIGVRTAPEFIFSVFCVPVGPYFKGG-LTPTNFI-TSDYDRAAPHGTGAAKVGGN 206 Query: 234 YGPTVLVQQEALKRGCEQVLWLYGPDH-QLTEVGTMNIFVYWTHEDGVLELVTPPLNGVI 292 Y ++L EA KR V++L H + E G N F +DG + VTP + I Sbjct: 207 YAASLLPGYEAKKRDFADVIYLDPATHTTIEEAGAANFFAIT--QDG-QKFVTPQ-SPSI 262 Query: 293 LPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILY 352 LP + + SLL +A+ V E I + +L G+ E GTA + P+ I + Sbjct: 263 LPSITKYSLLWLAEHRLGLEVEEGDIRIDEL------GKFSEAGACGTAAVITPIGGIQH 316 Query: 353 KDRNLHIPTMENGP-ELILRFQKELKEIQYGIRA--HEWMFPV 392 D + H+ E+ P + R EL IQYG + W+ V Sbjct: 317 GD-DFHVFYSESEPGPVTRRLYDELVGIQYGDKEAPEGWIVKV 358 >4DQN-A nrPDB Length = 345 Score = 352 bits (904), Expect = 1e-97, Method: Composition-based stats. Identities = 102/344 (29%), Positives = 174/344 (50%), Gaps = 20/344 (5%) Query: 55 LVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQ 114 L F + + D W ++ L + +S +LHY + FEG+KA++ KD Sbjct: 14 LGFEYHKLPFRYISYYKDGKWDDGKLTEDATLHISESSPALHYGQEAFEGLKAYRTKDGS 73 Query: 115 VRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPD-AAGTSLYVRPVL 173 V+LFRP +N +R+ R+A RL +P + ++ ++++ ++++VP G +LY+RP+L Sbjct: 74 VQLFRPNMNAERLQRTADRLLMPQVPTDKFIDAAKQVVRANEEYVPPYGTGATLYLRPLL 133 Query: 174 IGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGN 233 IG +GV + + PVG YF GG + P + L + RA G G K+GGN Sbjct: 134 IGVGDVIGVHPADEYIFTIFAMPVGNYFKGG-LAPTNFLIQDDYDRAAPHGTGAAKVGGN 192 Query: 234 YGPTVLVQQEALKRGCEQVLWLYGPDH-QLTEVGTMNIFVYWTHEDGVLELVTPPLNGVI 292 Y ++L + A +R V++L H ++ EVG+ N F E +TP L+ I Sbjct: 193 YAASLLPGKVAHERQFSDVIYLDPATHTKIEEVGSANFFGITKDN----EFITP-LSPSI 247 Query: 293 LPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILY 352 LP V + SLL +A+ + +E + + +L + + E GTA + P+ + + Sbjct: 248 LPSVTKYSLLYLAEHRFGMKAIEGDVCVDELDKFV------EAGACGTAAVISPIGGVQH 301 Query: 353 KDRNLHIP--TMENGPELILRFQKELKEIQYG-IRAHE-WMFPV 392 D + H+ E GP + + EL IQ+G ++A E W++ V Sbjct: 302 GD-DFHVFYSETEVGP-VTHKLYDELTGIQFGDVKAPEGWIYKV 343 >4WHX-A nrPDB Length = 311 Score = 313 bits (801), Expect = 1e-85, Method: Composition-based stats. Identities = 83/332 (25%), Positives = 143/332 (43%), Gaps = 29/332 (8%) Query: 65 MLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNM 124 M M + + K W ++ +++ +H + +LHY + +FEG++A+K D +FR + Sbjct: 5 MSMADRDGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHT 64 Query: 125 DRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQ 184 R+L SA + E LE +R D V + S Y+RP++ LGVS Sbjct: 65 KRLLNSAKIFQMDVPFDQETLEAAQR------DVVRENKLESCYLRPIIWIGSEKLGVSA 118 Query: 185 PTRALLF-VILCPVGAYFPGGSVTPVSLLADPAFIRAWVG-GVGNYKLGGNYGPTVLVQQ 242 + + P GAY + + +F R V + K G Y ++L Q Sbjct: 119 KGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQ 178 Query: 243 EALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLL 302 EA G ++ L L D ++E N F+ +L TP L L G+ R +++ Sbjct: 179 EATADGYDEALLL-DVDGYVSEGSGENFFLV-----NRGKLYTPDL-ASCLDGITRDTVI 231 Query: 303 DMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTM 362 +A+ G V+E+ IT ++ A E F +GTA +V P+ + + I Sbjct: 232 TLAKEAG-IEVIEKRITRDEVYTA------DEAFFTGTAAEVTPIRELDNR----TIGGG 280 Query: 363 ENGPELILRFQKELKEIQYGIRAH--EWMFPV 392 GP + + Q ++ G A +W+ + Sbjct: 281 ARGP-ITEKLQSAFFDVVNGKSAKHADWLTKI 311 >1IYD-A nrPDB Length = 309 Score = 305 bits (782), Expect = 2e-83, Method: Composition-based stats. Identities = 84/326 (25%), Positives = 144/326 (44%), Gaps = 28/326 (8%) Query: 66 LMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMD 125 + + D W + +++ +H S +LHY +FEG++ + V +FR +M Sbjct: 1 MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV-VFRHREHMQ 59 Query: 126 RMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQP 185 R+ SA P + I L+E +D + TS Y+RP++ + +GV+ P Sbjct: 60 RLHDSAKIYRFPV------SQSIDELMEACRDVIRKNNLTSAYIRPLIFVGDVGMGVNPP 113 Query: 186 TRALLFVI--LCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVG-NYKLGGNYGPTVLVQQ 242 VI P GAY ++ ++ RA + K GGNY ++LV Sbjct: 114 AGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGS 173 Query: 243 EALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLL 302 EA + G ++ + L + ++E N+F +DGV L TPP LPG+ R +++ Sbjct: 174 EARRHGYQEGIAL-DVNGYISEGAGENLFEV---KDGV--LFTPPFTSSALPGITRDAII 227 Query: 303 DMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTM 362 +A+ G V E+ ++ + L A EVF SGTA ++ PV + + + Sbjct: 228 KLAKELG-IEVREQVLSRESLYLA------DEVFMSGTAAEITPVRSVD----GIQVGEG 276 Query: 363 ENGPELILRFQKELKEIQYGIRAHEW 388 GP + R Q+ + G +W Sbjct: 277 RCGP-VTKRIQQAFFGLFTGETEDKW 301 >2EJ2-A nrPDB Length = 308 Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 85/322 (26%), Positives = 136/322 (42%), Gaps = 33/322 (10%) Query: 74 GWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMR 133 W P + S +LHY +FEG++A++ +FR ++ R SA Sbjct: 8 IWMNGAFVPQEEAKTSVLSHALHYGTSVFEGIRAYETAKGP-AIFRLKEHVKRFYNSAKV 66 Query: 134 LCLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTR--ALL 190 L + F EL E I+ ++ + S Y+RP+ +LGV+ A + Sbjct: 67 LRMEIPFAPEELEEAIKEVVRRN-------GYRSCYIRPLAWMGAKALGVNPLPNNPAEV 119 Query: 191 FVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGV-GNYKLGGNYGPTVLVQQEALKRGC 249 V GAY +V + L ++ R + G K+GGNY + L + EA+ G Sbjct: 120 MVAAWEWGAYLGEEAVRKGARLITSSWARFPANVMPGKAKVGGNYVNSALAKMEAVAAGA 179 Query: 250 EQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWG 309 ++ L L + + E N+F DGV+ + +N L G+ R S++ +A+ G Sbjct: 180 DEALLL-DEEGYVAEGSGENLFFV---RDGVIYALEHSVN---LEGITRDSVIRIAKDLG 232 Query: 310 EFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELI 369 + V T QL A EVF +GTA +V PV I ++ I GP + Sbjct: 233 -YEVQVVRATRDQLYMA------DEVFMTGTAAEVTPVSMIDWRP----IGKGTAGP-VA 280 Query: 370 LRFQKELKEIQYGIRA--HEWM 389 LR ++ E G R W+ Sbjct: 281 LRLREVYLEAVTGRRPEYEGWL 302 >6H65-A nrPDB Length = 317 Score = 265 bits (677), Expect = 3e-71, Method: Composition-based stats. Identities = 80/340 (23%), Positives = 141/340 (41%), Gaps = 59/340 (17%) Query: 73 KGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAF-KGKDQQVRLFRPWLNMDRMLRSA 131 GW + P+ +LH ++ + + LFEG++A+ + +Q+ +FR ++ R+ +SA Sbjct: 15 YGWMNGQCIPWDQCSLHVSTQAAFFGASLFEGVRAYWNAEREQLYVFRLDEHLRRLEQSA 74 Query: 132 ----MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVL-IGNEPS-LGVSQP 185 M+L +P D + + + R E D LYV I ++P L + Sbjct: 75 KMLRMKLSMPIADIRQGVLELLRANEFRSDV-------HLYVASYFGINHDPDPLFPTDD 127 Query: 186 TRALLFVILCPVGAYFPGGSVTPVSLLAD--PAFIRAWVG-----GVGNYKLGGNYGPTV 238 T G Y G +V+ + L+ A + +W K+G NY + Sbjct: 128 T-----------GVYVTGTAVSRLPLVHTGISACMSSWRRISDDSVPPRIKIGANYQNSR 176 Query: 239 LVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVR 298 L Q EA G + L G + V DG +++PP+ IL V R Sbjct: 177 LAQTEARVNGYHTSVLLNSRGKVSETPGACLLMV----RDG--RVISPPVTADILESVTR 230 Query: 299 QSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLH 358 ++L+ +++ + V+ER + +L A EVF GT ++ PV I + Sbjct: 231 KTLMSLSEAELDSPVIERDMDRTELYIA------EEVFLCGTIAEILPVTTID----RIQ 280 Query: 359 IPTMENGPELILRFQKELKEIQYGIRA------HEWMFPV 392 + E GP + L+E+ +G+ + W+ PV Sbjct: 281 VGDGEVGP-----VTRRLQELYFGVTSGQLEAYKSWLLPV 315 >6NST-A nrPDB Length = 307 Score = 263 bits (673), Expect = 7e-71, Method: Composition-based stats. Identities = 83/330 (25%), Positives = 148/330 (44%), Gaps = 34/330 (10%) Query: 65 MLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNM 124 M M + + W + +++ T H + + HY + +FEG++A+ Q +FR + Sbjct: 1 MSMADRDGVIWYDGELVQWRDATTHVLTHTHHYGMGVFEGVRAYDT-PQGTAIFRLQAHT 59 Query: 125 DRMLRSA--MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGV 182 DR+ SA M + +P + + E+ E R + + S Y+RP++ +G+ Sbjct: 60 DRLFDSAHIMNMQIP-YSRDEINEATRAAVREN-------NLESAYIRPMVFYGSEGMGL 111 Query: 183 SQPTRALLFVI-LCPVGAYFPGGSVTPVSLLADPAFIRAWVG-GVGNYKLGGNYGPTVLV 240 + +I GAY ++ + +F R V + K G Y ++L Sbjct: 112 RASGLKVHVIIAAWSWGAYMGEEALQQGIKVRTSSFTRHHVNISMTRAKSNGAYINSMLA 171 Query: 241 QQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQS 300 QEA+ G ++ + L P+ + E NIF+ +DGV + TP + L G+ R + Sbjct: 172 LQEAISGGADEAMML-DPEGYVAEGSGENIFII---KDGV--IYTPEVTAC-LNGITRNT 224 Query: 301 LLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIP 360 +L +A G F++VE+ IT ++ A E F +GTA +V P+ + + I Sbjct: 225 ILTLAAEHG-FKLVEKRITRDEVYIA------DEAFFTGTAAEVTPIREVDGR----KIG 273 Query: 361 TMENGPELILRFQKELKEIQYG-IRAH-EW 388 GP + + QK ++ G AH EW Sbjct: 274 AGRRGP-VTEKLQKAYFDLVSGKTEAHAEW 302 >5CE8-A nrPDB Length = 307 Score = 255 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 79/329 (24%), Positives = 145/329 (44%), Gaps = 45/329 (13%) Query: 73 KGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAM 132 K W R+ + + S SL+Y +FEG++A+ + + +FR +M+R+LRSA Sbjct: 14 KVWLDGRLVDEEEAKVTVLSPSLNYGFGVFEGIRAY-WNGENLYVFRLRDHMERLLRSAK 72 Query: 133 RLCLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVS-QPTRALL 190 + L + EL + + + + LY+RPV ++P + + + +A + Sbjct: 73 IIGLDVPYTAEELSKAVVETVRAN------GFKEDLYIRPVAYISKPQISLDVRGLQASV 126 Query: 191 FVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGN-----YKLGGNYGPTVLVQQEAL 245 + P G Y V A + +W + K G Y +++ EA Sbjct: 127 AIAAIPFGKYLKVEGVR--------AAVVSWRRVHTSMMPVMAKATGIYLNSIMAAVEAR 178 Query: 246 KRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMA 305 RG ++ + L + ++ E NIF+ GV L+TPPL IL G+ R++++ +A Sbjct: 179 ARGYDEAIMLN-AEGKVVEGSGENIFIV---RRGV--LMTPPLEDGILEGITRETVISIA 232 Query: 306 QTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENG 365 G ++E++IT ++L A E F GTA ++ P+ I + ++ G Sbjct: 233 GDLG-IPLLEKSITREELYAA------DEAFFVGTAAEITPIIEIDGR-------VLQRG 278 Query: 366 PELILRFQKELKEIQYGIRAH--EWMFPV 392 P + + + + I G W+ PV Sbjct: 279 P-ITQKIAETYRRIVLGKEEKYLPWLTPV 306 >5MQZ-A nrPDB Length = 290 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 69/312 (22%), Positives = 122/312 (39%), Gaps = 39/312 (12%) Query: 73 KGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAM 132 + P + Y +FEG++A+ G R+FR ++DR+ SA Sbjct: 3 YVYMDGEFVPENEAKVSIFDHGFLYGDGVFEGIRAYNG-----RVFRLKEHIDRLYDSAK 57 Query: 133 RLCLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQ--PTRAL 189 + L K E +E I + Y+RP++ LG+ Sbjct: 58 AIDLEIPITKEEFMEIILET-------LRKNNLRDAYIRPIVTRGIGDLGLDPRKCQNPS 110 Query: 190 LFVILCPVGAYFPGGSVTPVSLLADPAFIR--AWVGGVGNYKLGGNYGPTVLVQQEALKR 247 + VI P G + G + L A +R ++ N K NY +L + EA + Sbjct: 111 IIVITKPWGKLY--GDLYEKGLTAITVAVRRNSFDALPPNIK-SLNYLNNILAKIEANAK 167 Query: 248 GCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQT 307 G ++ ++L + ++E NIFV + TPP L G+ R++++++ Sbjct: 168 GGDEAIFL-DRNGYVSEGSGDNIFVVKNGA-----ITTPPTINN-LRGITREAVIEIINR 220 Query: 308 WGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPE 367 G E I + L A EVF +GTA ++ P+ I + I + G E Sbjct: 221 LG-IPFKETNIGLYDLYTA------DEVFVTGTAAEIAPIVVIDGR----KIGDGKPG-E 268 Query: 368 LILRFQKELKEI 379 + + +E ++ Sbjct: 269 ITRKLMEEFSKL 280 >5E25-A nrPDB Length = 291 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 63/309 (20%), Positives = 118/309 (38%), Gaps = 37/309 (11%) Query: 74 GWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMR 133 + P + Y +FEG++A+ GK +F+ + ++DR+ A Sbjct: 5 VYMNGEFVPESQAKVSVFDHGFLYGDGVFEGIRAYNGK-----VFKLYEHIDRLYDCARV 59 Query: 134 LCLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQ--PTRALL 190 + L K E E I + + Y+RP++ LG+ + Sbjct: 60 IDLKIPLSKEEFAEAILETLRRN-------NLRDAYIRPIVTRGAGDLGLDPRKCPSPNV 112 Query: 191 FVILCPVGAYFPGGSVTPVSLLADPAFI-RAWVGGVGNYKLGGNYGPTVLVQQEALKRGC 249 +I P G + G + L A I R + + NY +L + EA +G Sbjct: 113 IIITKPWGKLY--GDLYEKGLKAITVAIRRNAIDSLPPNIKSLNYLNNILAKIEANAKGG 170 Query: 250 EQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWG 309 ++ ++L + ++E NIF+ + TPP L G+ RQ ++++ Sbjct: 171 DEAIFL-DHNGYISEGSGDNIFIVKNGT-----ITTPPTLNN-LKGITRQVVIELINEL- 222 Query: 310 EFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELI 369 E E I + L A E+F +GTA ++ PV I + + + G ++ Sbjct: 223 EIPFREANIGLFDLYSA------DEIFVTGTAAEIAPVTYIDGR----TVGNGKPG-KVT 271 Query: 370 LRFQKELKE 378 ++ +E Sbjct: 272 KMLMEKFRE 280 >6GKR-A nrPDB Length = 316 Score = 193 bits (489), Expect = 2e-49, Method: Composition-based stats. Identities = 63/338 (18%), Positives = 121/338 (35%), Gaps = 40/338 (11%) Query: 65 MLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAF-KGKDQQVRLFRPWLN 123 M E W RI P++ T+H +FEG++ + + ++ +FR + Sbjct: 1 MSQQENPKYLWWNHRIIPWEEATVHLTDYWWASVTAVFEGIRGYWNNAEGEMYIFRLEDH 60 Query: 124 MDRMLRSAMRLCLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIG-NEPSLG 181 R+ +S + +P F E+ + L+ + +Y+ P+ + Sbjct: 61 ARRLEQSMQLIRMPKEFTVDEICQATIDLVRAND------YRGDVYIMPLAYAVGNKAFS 114 Query: 182 VSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGG-----VGNYKLGGNYGP 236 V +F+ P + + A +W K NY Sbjct: 115 VVGDRTTEMFIYSRPAVSRLEED-------FSLHACYSSWTRINERVLPPRIKALANYRN 167 Query: 237 TVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGV 296 + L EA G + L+L + ++ E +F + L+TP + IL + Sbjct: 168 SQLASSEAAMNGYDTALFLNP-EGKVAEGTGSCVFFVRKGK-----LITPDITSGILESI 221 Query: 297 VRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRN 356 R +++ +A+ V ER + + A E F GT ++ P+ I + Sbjct: 222 TRDTVIHLAREVLGLEVEERVVDRTETYLA------DEAFLCGTHAEITPIASIDRHE-- 273 Query: 357 LHIPTMENGPELILRFQKELKEIQYGI--RAHEWMFPV 392 + GP + + + +E+ YG R W+ PV Sbjct: 274 --MKHGAPGP-ITRQLRDIYREVVYGRDFRYRNWLTPV 308 >1G2W-A nrPDB Length = 282 Score = 118 bits (295), Expect = 5e-27, Method: Composition-based stats. Identities = 60/303 (19%), Positives = 117/303 (38%), Gaps = 36/303 (11%) Query: 75 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRL 134 W +I + + + + ++E +K + G+ +F ++DR+ SA ++ Sbjct: 5 W-NDQIVKDEEVKIDKEDRGYQFGDGVYEVVKVYNGE-----MFTVNEHIDRLYASAEKI 58 Query: 135 CLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVI 193 + + K + + + L+E ++ +Y + V G P +I Sbjct: 59 RITIPYTKDKFHQLLHELVEKNELNT-----GHIYFQ-VTRGTSPRAHQFPENTVKPVII 112 Query: 194 LCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVL 253 P ++ IR W+ + K N VL +QEA ++GC + + Sbjct: 113 GYTKENPRPLENLEKGVKATFVEDIR-WLRC--DIK-SLNLLGAVLAKQEAHEKGCYEAI 168 Query: 254 WLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRV 313 ++ +T + N+F +DG+ L T P N +IL G+ R ++ A V Sbjct: 169 L--HRNNTVTSGSSSNVFGI---KDGI--LYTHPANNMILKGITRDVVIACANEI-NMPV 220 Query: 314 VERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQ 373 E T + ++ E+F + T ++ PV I K I + G E + Q Sbjct: 221 KEIPFTTHE------ALKMDELFVTSTTSEITPVIEIDGK----LIRDGKVG-EWTRKLQ 269 Query: 374 KEL 376 K+ Sbjct: 270 KQF 272 >4JXU-A nrPDB Length = 295 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 69/289 (23%), Positives = 111/289 (38%), Gaps = 41/289 (14%) Query: 72 DKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA 131 D W + P S ++ +F+G + F G L+ R+ RSA Sbjct: 18 DGEWLAG-----NPPLIGPTSHAMWLGSTVFDGARWFDGIAPD-----LDLHCQRVNRSA 67 Query: 132 MRLCL-PSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPS---LGVSQ-PT 186 L L P+ E+ ++ T++YV+P+ G S + V T Sbjct: 68 EALGLKPTMSAEEIEGLAWEGVK------KFDGKTAIYVKPMYWGEHGSWSVVAVDPEST 121 Query: 187 RALLFVILCPVGAYFPGGSVTPVSLLADP-AFIRAWVGGVGNYKLGGNYGPTVLVQQEAL 245 R L + P+G G S+T + + K G Y + EA Sbjct: 122 RFALCLFEAPMGNGHAGSSLTLSPFRRPTLECM------PTDAKAGCLYPNNARILNEAR 175 Query: 246 KRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMA 305 RG + L + + E G+ NIF+ +DGV + TP N L G+ R ++ + Sbjct: 176 SRGFDNAL-VRDMLGNIAETGSSNIFMV---KDGV--VFTPAANRTFLAGITRSRVMGLL 229 Query: 306 QTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKD 354 G F V+E ++TM A E+F SG +V PV R+ ++ Sbjct: 230 SEAG-FEVIETSLTMADFEGA------DEIFTSGNYSKVLPVTRLEQRE 271 >4PBC-A nrPDB Length = 316 Score = 100 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 51/300 (17%), Positives = 107/300 (35%), Gaps = 27/300 (9%) Query: 79 RIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPS 138 + P + + ++E + + D FR ++DR+ RS ++ + + Sbjct: 27 ELVPLSEARVPVLDRGFIFGDGVYEVVPVY-AHDGAHVPFRIEQHLDRLARSLKKIGIDN 85 Query: 139 FDKLELLEC-IRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPV 197 I R++ + + + D +Y++ + G + P A+ V Sbjct: 86 PHDAAGWRALIERVVAANAEGLGDGN-ALVYLQ--VTRGVAKRGHAFPANAVPTVFAMTS 142 Query: 198 GAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYG 257 P + A R W+ + K G ++ Q A +R + + L Sbjct: 143 PLRLPSEEERAKGVRCVTAEDRRWLHC--DIKSISLLGNVLMAQ-HAAERDAFETIQLRD 199 Query: 258 PDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERT 317 + +TE + N+++ EL PP + IL G+ R +L++ R V R Sbjct: 200 EN--VTEGSSSNVWIVKNG-----ELFAPPRSNKILEGI-RYALVEQLADECGIRFVARE 251 Query: 318 ITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELK 377 I+ +L A E+ + ++ PV + +L + + GP + + Sbjct: 252 ISEVELRSA------DEIMLTSATKEILPVTSLD----DLPVQGGKPGP-VFAALYDAYQ 300 >4TM5-A nrPDB Length = 311 Score = 98.3 bits (243), Expect = 6e-21, Method: Composition-based stats. Identities = 54/310 (17%), Positives = 109/310 (35%), Gaps = 30/310 (9%) Query: 79 RIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPS 138 + P + + ++E + + + + FR ++ R+ RS ++ + Sbjct: 27 ELVPLSEARVPVLDRGFIFGDGVYEVVPIY-AEGARRAPFRIAQHLARLARSLKKIGIAD 85 Query: 139 FDKLELLECIR-RLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPV 197 + RL++ + + D +Y++ + G + P A+ V Sbjct: 86 PHDEAGWRALVARLVDANAAALGDGQHAIVYIQ--VTRGVAKRGHAFPANAVPTVFAMAS 143 Query: 198 GAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYG 257 P + + A R W+ + K G ++ Q A + + + L Sbjct: 144 PLALPTDAQRAQGVHCVTAEDRRWLHC--DIKSVSLLGNVLMAQ-HAAEHDAAETIQL-- 198 Query: 258 PDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERT 317 D +TE + N+++ EL+ PP + IL G+ R +L++ R V R Sbjct: 199 RDGNVTEGSSSNVWIVKNG-----ELIAPPRSNRILEGI-RYALVEELAEECGIRFVARE 252 Query: 318 ITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELK 377 I +L A E+ + ++ PV R+ +L + GP L Sbjct: 253 INEAELRAA------DEILLTSATKEILPVTRLD----DLPVQGGRPGP-----VFDALY 297 Query: 378 EIQYGIRAHE 387 +AHE Sbjct: 298 AAYQRAKAHE 307 >3CSW-A nrPDB Length = 285 Score = 96.7 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 61/294 (20%), Positives = 113/294 (38%), Gaps = 47/294 (15%) Query: 74 GWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMR 133 W + + + ++L + ++E ++ + F + + R+ RSA Sbjct: 15 IWWRGKFRRADEISLDFSLFEKSLQGAVYETLRTYSRAP-----FAAYKHYTRLKRSADF 69 Query: 134 LCLP-SFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFV 192 LP S E + ++ + K V +Y+ P + L V P + Sbjct: 70 FNLPLSLSFDEFTKVLKAGADEFKQEVR----IKVYLFP---DSGEVLFVFSPLN----I 118 Query: 193 ILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQV 252 G +V + L+ P K+ G VL ++E + C V Sbjct: 119 PDLETGVEVKISNVRRIPDLSTP----------PALKITGR-TDIVLARREIVD--CYDV 165 Query: 253 LWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFR 312 + L G + Q+ E N+F+ + L+TP L+ IL G+ R++++ +A++ E Sbjct: 166 ILL-GLNGQVCEGSFSNVFLVKEGK-----LITPSLDSGILDGITRENVIKLAKSL-EIP 218 Query: 313 VVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGP 366 V ER + + +L A E+F + T+ V PV R+ E GP Sbjct: 219 VEERVVWVWELFEA------DEMFLTHTSAGVVPVRRLNEHS----FFEEEPGP 262 >4UUG-A nrPDB Length = 332 Score = 88.7 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 48/281 (17%), Positives = 97/281 (34%), Gaps = 33/281 (11%) Query: 116 RLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIG 175 R FR ++ R+L S ++ L + + + + + V + +V ++ Sbjct: 67 RFFRLDDHLQRILESCDKMRL------KFPLALSSVKNILAEMVAKSGIRDAFVEVIVTR 120 Query: 176 NEPSLGVSQP----TRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLG 231 + S+P + ++L + P + + R G Sbjct: 121 GLTGVRGSKPEDLYNNNIYLLVLPYIWVMAPENQLHGGEAIITRTVRRTPPGAFDPTIKN 180 Query: 232 GNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGV 291 +G EA+ RG +L D LTE NI + + TP + Sbjct: 181 LQWGDLTKGLFEAMDRGA-TYPFLTDGDTNLTEGSGFNIVLVKNG-----IIYTP--DRG 232 Query: 292 ILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRIL 351 +L G+ R+S++D+A + + ++Q E+F TA + P+ + Sbjct: 233 VLRGITRKSVIDVA-RANSIDIRLEVVPVEQAY------HSDEIFMCTTAGGIMPITLLD 285 Query: 352 YKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 392 + + + GP + + E+ Y + FPV Sbjct: 286 GQP----VNDGQVGP-ITKKIWDGYWEMHYN---PAYSFPV 318 >2Y4R-A nrPDB Length = 292 Score = 71.7 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 58/309 (18%), Positives = 99/309 (32%), Gaps = 42/309 (13%) Query: 75 WGQPRIQPFQN----LTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRS 130 + Q + + + L L Y LFE + G + ++ R+ Sbjct: 17 YFQGHMLDWVDGRPAAELSVRDRGLAYGDGLFETLAVRAGTPRL-----LERHLARLEEG 71 Query: 131 AMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRAL- 189 RL +P D L + + D V ++ E G + P A Sbjct: 72 CRRLAIP-LDTAALRQELLAFCAALGDGVAKL---------IVTRGEGLRGYAPPAEASP 121 Query: 190 LFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGC 249 ++ +P L R + N VL + E G Sbjct: 122 RRILSGSPRPAYPERHWQQGVRLFACR-TRLAEQPLLAGLKHLNRLEQVLARAEWSDAGH 180 Query: 250 EQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWG 309 + L L ++ E N+ + DG LV P L + GV+R LL+ A+ G Sbjct: 181 AEGLML-DVHERVVEGVFSNLLLVL---DGT--LVAPDLRRCGVAGVMRAELLERAEGIG 234 Query: 310 EFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELI 369 + R ++M +L A EVF + + PV + + EL Sbjct: 235 -VPLAIRDVSMAELATA------DEVFLCNSQFGIWPVRALDEH--------VWPVGELT 279 Query: 370 LRFQKELKE 378 + Q +L++ Sbjct: 280 RKLQDQLRD 288 >1ET0-A nrPDB Length = 269 Score = 57.5 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 42/269 (15%), Positives = 90/269 (33%), Gaps = 37/269 (13%) Query: 84 QNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCL-----PS 138 + +L + + + F + GK + ++ R+ + RL + P Sbjct: 8 KQESLAVSDRATQFGDGCFTTARVIDGK-----VSLLSAHIQRLQDACQRLMISCDFWPQ 62 Query: 139 FDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVG 198 ++ + V K + +G Y +L TR +L V P Sbjct: 63 LEQEMKTLAAEQQNGVLKVVISRGSGGRGY---------STLNSGPATR-ILSVTAYPA- 111 Query: 199 AYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGP 258 + + + +R N VL++ + ++ L L Sbjct: 112 ---HYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNADEALVLDS- 167 Query: 259 DHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTI 318 + +TE N+F + + TP L+ + G++RQ + + +++VE Sbjct: 168 EGWVTECCAANLFWRKGN-----VVYTPRLDQAGVNGIMRQFCIRLLAQ-SSYQLVEVQA 221 Query: 319 TMKQLLRALEEGRVREVFGSGTACQVCPV 347 ++++ L+A E+ V PV Sbjct: 222 SLEESLQA------DEMVICNALMPVMPV 244 >3SNO-A nrPDB Length = 315 Score = 57.1 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 58/341 (17%), Positives = 96/341 (28%), Gaps = 68/341 (19%) Query: 37 LQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLH 96 L +E ++ P P+VF W + Sbjct: 17 LIVEPYGGSIRQQNPNLPMVF-----------------WDDAALTR-------------- 45 Query: 97 YSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDK 156 +FE + G VR + +R SA L LP + + + IE Sbjct: 46 -GDGIFETLLIRDGHACNVR-----RHGERFKASAALLGLPEPILEDWEKATQMGIESWY 99 Query: 157 DWVPDAAGTSLYV-----RPVLIGNEPSLGVSQ-------PTRALLFVILCPVGAYFPGG 204 P+A S R L ++ + V+ G G Sbjct: 100 SH-PNAGEASCTWTLSRGRSSTGLASGWLTITPVSSDKLAQREHGVSVMTSSRGYSIDTG 158 Query: 205 --SVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQL 262 + + R + Y + + A G + V++ G ++ Sbjct: 159 LPGIGKATRGELSKVERTPAPWLTVGAKTLAYAANMAALRYAKSNGFDDVIFTDGD--RV 216 Query: 263 TEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQ 322 E T + + + + TP G ILPG + +L A G +R E+ +++ Sbjct: 217 LEGATSTVVSFKGDK-----IRTPSPGGDILPGTTQAALFAHATEKG-WRCKEKDLSIDD 270 Query: 323 LLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTME 363 L A V V G PV L P E Sbjct: 271 LFGADSVWLVSSVRG--------PVRVTRLDGHKLRKPDNE 303 >4K6N-A nrPDB Length = 383 Score = 41.7 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 41/135 (30%), Gaps = 8/135 (5%) Query: 208 PVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGT 267 P++ A +F ++ L E + + L E Sbjct: 250 PLNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCEILFSNKSGLLMEGSI 309 Query: 268 MNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRAL 327 N+ V +G + VTP L L G +R LL + + E I + L Sbjct: 310 TNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGL------IEEGDIDIGSLTVGN 363 Query: 328 EEGRVREVFGS--GT 340 E V G GT Sbjct: 364 EVLLFNGVMGCIKGT 378 >6CQB-A nrPDB Length = 394 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 24/56 (42%) Query: 319 TMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQK 374 T++++ A V GTA V++ Y D I E+ EL +F++ Sbjct: 4 TVEEIWAAQRARGPATVLAIGTAAPANVVYQADYPDYYFRITKSEHMTELKEKFRR 59 >3E96-A nrPDB Length = 316 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 39/107 (36%), Gaps = 4/107 (3%) Query: 105 MKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLEL-LECIRRLIEVDKDWVPDAA 163 + F+ D + +DR++ + + + +P + E + E + V Sbjct: 20 ITPFRKSDGSIDWHHYKETVDRIVDNGIDVIVPCGNTSEFYALSLEEAKEEVRRTVEYVH 79 Query: 164 GTSLYVRPVLIGNEPSLGV---SQPTRALLFVILCPVGAYFPGGSVT 207 G +L V + ++ + ++ A +I P+ Y G V Sbjct: 80 GRALVVAGIGYATSTAIELGNAAKAAGADAVMIHMPIHPYVTAGGVY 126 >6ED1-A nrPDB Length = 879 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 262 LTEVGTMNIFVYWTHEDGVLELVTPPLNG--VILPGVVRQSLLD 303 + EVG N+ L + PP++G I G+ R+ L Sbjct: 133 ICEVGKENLLAVKVDNSSSLGEILPPVSGDFSIFGGIYRRVFLQ 176 >1IW7-A nrPDB Length = 315 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Query: 291 VILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRI 350 +PGV ++ ++++ E V +++ + L+ +EV A PV + Sbjct: 66 STIPGV-KEDVVEIILNLKELVVRFLNPSLQTVTLLLKAEGPKEV----KARDFLPVADV 120 Query: 351 LYKDRNLHIPTMENGPELILRFQ 373 + +LHI T+E G L + + Sbjct: 121 EIMNPDLHIATLEEGGRLNMEVR 143 >5D1F-A nrPDB Length = 413 Score = 28.2 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 35/100 (35%), Gaps = 12/100 (12%) Query: 93 SSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMR------LCLPSFDKLELLE 146 S++ +L FE A +G LF +MDR++ + L L + + E Sbjct: 140 HSVNAALGQFENCLADRGCAVNTHLFSLIDDMDRLIEVIKQAAKEGALVLYTLADPSMAE 199 Query: 147 CIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPT 186 + + W +RP + +GV+ Sbjct: 200 ATK---KACDFWGVPCTDV---LRPTVEAIASHIGVAPSG 233 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.127 0.344 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,759,456 Number of Sequences: 36641 Number of extensions: 558402 Number of successful extensions: 1533 Number of sequences better than 10.0: 33 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1362 Number of HSP's gapped (non-prelim): 54 length of query: 392 length of database: 10,336,785 effective HSP length: 99 effective length of query: 293 effective length of database: 6,709,326 effective search space: 1965832518 effective search space used: 1965832518 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.8 bits)