BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O15296 (676 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4NRE-A nrPDB 1395 0.0 3O8Y-A nrPDB 569 e-162 2P0M-A nrPDB 450 e-127 2FNQ-A nrPDB 415 e-116 3VF1-A nrPDB 398 e-111 3RDE-A nrPDB 395 e-110 3D3L-A nrPDB 372 e-103 5MEF-A nrPDB 240 1e-63 4G32-A nrPDB 224 1e-58 1RRL-A nrPDB 181 6e-46 2IUJ-A nrPDB 176 2e-44 2IUK-A nrPDB 172 5e-43 4WFO-A nrPDB 162 5e-40 6NS2-A nrPDB 136 3e-32 5FNO-A nrPDB 124 1e-28 5FX8-A nrPDB 103 2e-22 5EK8-A nrPDB 53 4e-07 1Y1X-A nrPDB 35 0.10 4FGZ-A nrPDB 33 0.53 2VD3-A nrPDB 31 1.6 1QO0-A nrPDB 31 1.7 4KC3-B nrPDB 30 4.6 2KD3-A nrPDB 29 5.6 5Z57-K nrPDB 29 6.4 5DWN-A nrPDB 29 8.7 >4NRE-A nrPDB Length = 696 Score = 1395 bits (3611), Expect = 0.0, Method: Compositional matrix adjust. Identities = 676/676 (100%), Positives = 676/676 (100%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED Sbjct: 21 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 80 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE Sbjct: 81 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 140 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK Sbjct: 141 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 200 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS Sbjct: 201 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 260 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT Sbjct: 261 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 320 Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV Sbjct: 321 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 380 Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL Sbjct: 381 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 440 Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI Sbjct: 441 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 500 Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ Sbjct: 501 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 560 Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT Sbjct: 561 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 620 Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL Sbjct: 621 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 680 Query: 661 PYTYLDPPLIENSVSI 676 PYTYLDPPLIENSVSI Sbjct: 681 PYTYLDPPLIENSVSI 696 >3O8Y-A nrPDB Length = 691 Score = 569 bits (1466), Expect = e-162, Method: Compositional matrix adjust. Identities = 288/681 (42%), Positives = 425/681 (62%), Gaps = 15/681 (2%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 M + V V+TG AGT D + +S+VG+ G S LD F GA + + VT+ E+ Sbjct: 21 MPSYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDK--GSFERGAVDSYDVTVDEE 78 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 +G + L+R+ K G + D W+ ++ L P G ++ FPCY+W+ G +VL++ Sbjct: 79 LGEIQLVRIEKRK-----YG--SNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRD 131 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ + K Sbjct: 132 GRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEK 191 Query: 181 NANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239 +F L A + I + + W + ++IF +E HWQED F Sbjct: 192 GVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFG 251 Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299 QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI Sbjct: 252 YQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGID 311 Query: 300 TNVIN-GKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKT 358 N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK Sbjct: 312 ANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKI 370 Query: 359 WVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARE 418 WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FKLL+ H R+T+ INT ARE Sbjct: 371 WVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKARE 430 Query: 419 LLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVE---DIPGYYYRD 475 LI + D++ G G +++QR MK L Y+ LC PE I+ RG+E DIP Y+YRD Sbjct: 431 QLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRD 490 Query: 476 DGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETR 535 DG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++R Sbjct: 491 DGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSR 550 Query: 536 EALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLP 595 E L +Y+T+VIFT SA+HAAV+ GQ+D +W+PN PP+M+ PPPT+KG+ T E + TLP Sbjct: 551 EQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLP 610 Query: 596 PVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERN 655 +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ERN Sbjct: 611 DRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERN 670 Query: 656 QGLVLPYTYLDPPLIENSVSI 676 + L LPY YL P I NSV+I Sbjct: 671 ENLQLPYYYLSPDRIPNSVAI 691 >2P0M-A nrPDB Length = 662 Score = 450 bits (1158), Expect = e-127, Method: Compositional matrix adjust. Identities = 256/684 (37%), Positives = 381/684 (55%), Gaps = 35/684 (5%) Query: 4 FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEF--TAGAEEDFQVTLPEDV 61 +RV VSTG + AG+ +KV + +VG GE LG T EE+F+V + + + Sbjct: 3 YRVCVSTGASIYAGSKNKVELWLVGQHGEV------ELGSCLRPTRNKEEEFKVNVSKYL 56 Query: 62 GRVLLLRVHKAPPVLPLLGPLAPDAWFCRWF--QLTPPRGGHLLFPCYQWLEGAGTLVLQ 119 G +L +R+ K L DAWFC W Q FPCY+W+ G G L Sbjct: 57 GSLLFVRLRKK-------HFLKEDAWFCNWISVQALGAAEDKYWFPCYRWVVGDGVQSLP 109 Query: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179 GT + D + Q+ R++EL+ R+++YQW ++ G + + DL ++ ++ Sbjct: 110 VGTGCTTVGDPQGLFQKHREQELEERRKLYQWGSWKEGLILNVAGSKLTDLPVDERFLED 169 Query: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239 K +F AE+ +K L+ W++L++ RIF R+ A + WQED+ F Sbjct: 170 KKIDFEASLAWGLAELALKNSLNILAPWKTLDDFNRIFWCGRSKLARRVRDSWQEDSLFG 229 Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTS-LQAELEK----GSLFLVDHGI 294 QFLNG NP+L+RR LP V PG LQA+LEK G+LF D + Sbjct: 230 YQFLNGANPMLLRRSVQLPARL---------VFPPGMEELQAQLEKELKAGTLFEADFAL 280 Query: 295 LSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP--IFLPTDDKWD 352 L I+ NVI Q+ AAP+ +L P G L+P+ IQL +SP +FLPTD Sbjct: 281 LDNIKANVILYCQQYLAAPLVMLKLQPD-GKLMPMVIQLHLPKIGSSPPPLFLPTDPPMV 339 Query: 353 WLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHI 412 WLLAK WVR+++F HE +HLL HL+ EVFT+AT+R LP HP+FKL++PH RYTL I Sbjct: 340 WLLAKCWVRSSDFQVHELNSHLLRGHLMAEVFTVATMRCLPSIHPVFKLIVPHLRYTLEI 399 Query: 413 NTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYY 472 N AR L+ + D+ G G +L+Q+ L Y C P+D+ RG+ + + Sbjct: 400 NVRARNGLVSDFGIFDQIMSTGGGGHVQLLQQAGAFLTYRSFCPPDDLADRGLLGVESSF 459 Query: 473 YRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSL 532 Y D +++W + R+V I+G+YY +DE+V+DD ELQ+W REI G + G P+SL Sbjct: 460 YAQDALRLWEIISRYVQGIMGLYYKTDEAVRDDLELQSWCREITEIGLQGAQKQGFPTSL 519 Query: 533 ETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIA 592 ++ +VTM IFTC+ +H+++ GQ D W+PN P +M+LPPPT+K AT E +A Sbjct: 520 QSVAQACHFVTMCIFTCTGQHSSIHLGQLDWFTWVPNAPCTMRLPPPTTKD-ATLETVMA 578 Query: 593 TLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQ 652 TLP ++ + + +W L ++ PLG + +E+F+ PR + F+ LA + + I+ Sbjct: 579 TLPNLHQSSLQMSIVWQLGRDQPIMVPLGQHQEEYFSGPEPRAVLEKFREELAIMDKEIE 638 Query: 653 ERNQGLVLPYTYLDPPLIENSVSI 676 RN+ L +PY YL P ++ENSV+I Sbjct: 639 VRNEKLDIPYEYLRPSIVENSVAI 662 >2FNQ-A nrPDB Length = 699 Score = 415 bits (1066), Expect = e-116, Method: Compositional matrix adjust. Identities = 235/703 (33%), Positives = 383/703 (54%), Gaps = 38/703 (5%) Query: 2 AEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPED 60 A + V V TG+ AGT +++ I G +G + L LD +F AG++E + V D Sbjct: 7 AIYNVEVETGDREHAGTDATITIRITGAKGRTDYLKLDKWFHNDFEAGSKEQYTVQ-GFD 65 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VG + L+ +H PD + R ++ + FPC++W+ +VL Sbjct: 66 VGDIQLIELHSDGGGY---WSGDPDWFVNRVIIISSTQDRVYSFPCFRWV--IKDMVLFP 120 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 G A + + + ++ +QRQ+EL+ R+ YQW + P + KT +DL +++++ K Sbjct: 121 GEATLPFNEVPAIVSEQRQKELEQRKLTYQWDYVSDDMPGNIKAKTHDDLPRDVQFTDEK 180 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 + ++ +A + I L W S ++ ++ + + W ED +F Sbjct: 181 SRSYQESRKAALVNLGIGSLFTMFENWDSYDDYHILYRNWILGGTPNMADRWHEDRWFGY 240 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNG NPV++ RC LP NFPVT+ V + L G +L E++ G +++VD +L G ++ Sbjct: 241 QFLNGANPVILTRCDALPSNFPVTNEHVNASLDRGKNLDEEIKDGHIYIVDFKVLVGAKS 300 Query: 301 NVINGKP--------------------QFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPN 340 G P ++ AAP+ L Y + G L+P+AIQ++Q PGP Sbjct: 301 Y---GGPVLEDIGYKVPDHLKHDEADIRYCAAPLALFYVNK-LGHLMPIAIQINQEPGPE 356 Query: 341 SPIFLP-TDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLF 399 +PI+ P +++ DW++AK W+ AE +FH+ THLL +HL E F L+T R L HP+F Sbjct: 357 NPIWTPHEENEHDWMMAKFWLGVAESNFHQLNTHLLRTHLTTESFALSTWRNLASAHPVF 416 Query: 400 KLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPED 459 KLL PH L I+T+ R+ LI G +VD+S +G G +++ K++N LP Sbjct: 417 KLLQPHIYGVLAIDTIGRKELIGSGGIVDQSLSLGGGGHVTFMEKCFKEVNLQDYHLPNA 476 Query: 460 IRTRGVED---IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIF 516 ++ RGV+D +PG+YYRDDG+ +W A+E F+ EII I+Y +D+ V+ D E+Q+W+ ++ Sbjct: 477 LKKRGVDDPSKLPGFYYRDDGLALWEAIETFIGEIIAIFYKNDDDVKRDNEIQSWIYDVH 536 Query: 517 SKGFL---NQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPS 573 G+ + G+P+S E+RE L + +T ++FT S +HAAV+ Q D + PN P Sbjct: 537 KNGWRVNPGHQDHGVPASFESREQLKEVLTSLVFTFSCQHAAVNFSQKDHYGFTPNAPAV 596 Query: 574 MQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAP 633 ++ PPP KG AT + ++TLP + I +++L+K D+R LG Y + ++ Sbjct: 597 LRHPPPKKKGEATLQSILSTLPSKSQAAKAIATVYILTKFSEDERYLGNYSATAWEDKDA 656 Query: 634 RRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676 +I FQ +L IS+ I++RN+ L +PY YL P I N +I Sbjct: 657 LDAINRFQDKLEDISKKIKQRNENLEVPYIYLLPERIPNGTAI 699 >3VF1-A nrPDB Length = 698 Score = 398 bits (1023), Expect = e-111, Method: Compositional matrix adjust. Identities = 226/688 (32%), Positives = 379/688 (55%), Gaps = 24/688 (3%) Query: 3 EFRVRVSTGEAFGAGTWDKVSVSIVGTRG-ESPPLPLDN-LGKEFTAGAEEDFQVTLPED 60 ++++ V TG+ GAGT VS+ + G G E+ LD +F +G + + + D Sbjct: 21 KYKITVETGDLRGAGTDASVSIKLTGKDGAETSAFSLDKYFHNDFESGGTDTYDQS-GVD 79 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWF--QLTPPRG--GHLLFPCYQWLEGAGTL 116 VG + ++ + + G L D + + ++ G +FPCY+W+ L Sbjct: 80 VGEIAMITLKENG-----FG-LKSDWYIAKVIIEKIDEATGFSNKYIFPCYRWV--IKQL 131 Query: 117 VLQEGTAKV-SWADHHPVLQQQRQEELQARQEMYQWKA---YNPGWPHCLDEKTVEDLEL 172 V+ EG A + + D+ + +QR +E+ +++Y+W Y P +D + + L Sbjct: 132 VVYEGKAILPNSKDNVKTIAEQRTKEVSENKKLYKWGTDPRYVQDLPGFVDAEEPKSLPK 191 Query: 173 NIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHW 232 +++++ ++ + + FA + + L W L + +++ HA E+W Sbjct: 192 DVQFTDEATSSLFRVGLADFANLGLSHLFGIWDDWDCLEDFRQLITPAIKSGLPHAAEYW 251 Query: 233 QEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDH 292 ++D +F SQFLNG NP +IRRC LP+NFPV + MV +L G +L+ +++G +F+ D+ Sbjct: 252 RDDVWFGSQFLNGSNPEVIRRCDKLPENFPVKNEMVEKLLDRGYTLEKAMKEGLIFITDY 311 Query: 293 GILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLP-TDDKW 351 IL GI T ++ P+ L Y ++P+AIQL Q PG N+ I+ P D +W Sbjct: 312 KILEGIPTMDTPEDKRYITTPLGLFYLK-NNDDIIPIAIQLYQQPGENNSIWTPLKDTEW 370 Query: 352 DWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLH 411 DW++AK W+R A+ +H+ +THLL HL+ E +++ R LP HP++KLL PHT+ + Sbjct: 371 DWIMAKLWLRCADTQYHQMITHLLRCHLMMEPTAVSSWRNLPSVHPVWKLLYPHTKGIMA 430 Query: 412 INTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGY 471 INTL R LI G D+ IG G L+Q++ + + + L +D+R RGV+ + + Sbjct: 431 INTLGRNDLIPTGGAADKVLSIGGGGQVTLMQKHYRSVTFDSYDLVKDLRQRGVDGLRKF 490 Query: 472 YYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGF---LNQESSGI 528 YY+DD + +W + +FV +II IYY D+SV+ D E+Q W+R++ G+ + + Sbjct: 491 YYKDDALLLWNVIHQFVQDIIQIYYNDDDSVKKDNEIQDWIRDLHENGYPAGSDGTDKKV 550 Query: 529 PSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCE 588 P S E RE LV ++T+V+FTCS +HAAV+ Q + + PN P M+ PPPT KG + + Sbjct: 551 PKSFENREELVHFLTVVVFTCSCQHAAVNFSQMATYGFHPNSPTLMRQPPPTEKGKSNHK 610 Query: 589 GFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQIS 648 +A+L + ++ + L+ ++ LG Y D F + A ++A F+S LA I+ Sbjct: 611 VIMASLANKHQAVTMVSVVNALTTIYPTEKFLGDYADNLFGDAAAHAAMAKFKSNLANIT 670 Query: 649 RGIQERNQGLVLPYTYLDPPLIENSVSI 676 + I ERNQG+V PYT+L P + NS++I Sbjct: 671 KQITERNQGMVSPYTWLIPGHVPNSIAI 698 >3RDE-A nrPDB Length = 573 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 214/562 (38%), Positives = 311/562 (55%), Gaps = 16/562 (2%) Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTA+ D + ++ R+EEL R+++Y+W + G + + DL ++ ++ K Sbjct: 22 GTARTVVDDPQGLFKKHREEELAERRKLYRWGNWKDGLILNIASTGIHDLPVDERFLEDK 81 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 +F A++ +K L+ W SL+ RIF ++ AE + W+EDA F Sbjct: 82 RIDFEASLAKGLADLAVKDSLNVLMSWNSLDSFNRIFWSGQSKLAERVRDSWKEDALFGY 141 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEK----GSLFLVDHGILS 296 QFLNG NP+L+R LP M LQA+LEK G+LF D +L Sbjct: 142 QFLNGTNPMLLRHSVELPARLKFPPGM--------EELQAQLEKELQGGTLFEADFSLLD 193 Query: 297 GIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS--QTPGPNSPIFLPTDDKWDWL 354 GI+ NVI Q+ A P+ +L P G LLP+ IQL + P P+FLPTD WL Sbjct: 194 GIKANVILSSQQYLAVPLVMLKLQPD-GKLLPMVIQLQLPREGSPLPPLFLPTDPPMVWL 252 Query: 355 LAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINT 414 LAK WVR+++F HE +HLL HL+ EV +AT+R LP HP+FKLLIPH RYT+ IN Sbjct: 253 LAKCWVRSSDFQLHELHSHLLRGHLMAEVIAVATMRCLPSIHPIFKLLIPHFRYTMEINV 312 Query: 415 LARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYR 474 AR L+ + D+ G G EL++R L YS C P+D+ RG+ + +Y Sbjct: 313 RARNGLVSDLGIFDQVVSTGGGGHVELLRRAAALLTYSSFCPPDDLADRGLLGVESSFYA 372 Query: 475 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 534 D +++W + R+V I+ ++Y +DESV++D ELQAW RE G L + G P SL++ Sbjct: 373 QDALRLWEVISRYVEGIVSLHYKTDESVKEDFELQAWCREFTEIGLLGAQDRGFPVSLQS 432 Query: 535 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 594 +E L +VTM IFTC+ +H++ GQ D W+PN P +M+LPPPT+K AT E +ATL Sbjct: 433 KEQLCHFVTMCIFTCTGQHSSNHLGQLDWYTWVPNAPCTMRLPPPTTKD-ATLETVMATL 491 Query: 595 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 654 P + + W L + LG + +E+F+ P+ + F+ LA + + I+ R Sbjct: 492 PNFHQASLQMSITWQLGRCQPTMVALGQHEEEYFSGPGPKAVLTKFREELAALDKDIEVR 551 Query: 655 NQGLVLPYTYLDPPLIENSVSI 676 N L LPY YL P +ENSV+I Sbjct: 552 NAKLALPYEYLRPSRVENSVAI 573 >3D3L-A nrPDB Length = 541 Score = 372 bits (956), Expect = e-103, Method: Compositional matrix adjust. Identities = 193/498 (38%), Positives = 285/498 (57%), Gaps = 7/498 (1%) Query: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239 +N +F + EM +K + W L + +IF +++ AE + WQ+D F+ Sbjct: 16 ENLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFS 75 Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299 QFLNG NP+L+RR LP + M L+ EL+ GSLF D +L GI Sbjct: 76 YQFLNGANPMLLRRSTSLPSRLVLPSGMEEL----RAQLEKELQNGSLFEADFILLDGIP 131 Query: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP--IFLPTDDKWDWLLAK 357 NVI G+ Q+ AAP+ +L P G L P+ IQ+ + +FLP+D WLLAK Sbjct: 132 ANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAK 190 Query: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 417 +WVRN++F HE HLL++HL+ EV +AT+R LP HP+FK LIPH RYT+ INT AR Sbjct: 191 SWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRAR 250 Query: 418 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDG 477 LI G + D++ G G +L++R QL Y LC P+D+ RG+ +PG Y D Sbjct: 251 TQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDA 310 Query: 478 MQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREA 537 +++W + R+V I+ ++Y D+ V+ D ELQAW REI G + G P S +++ Sbjct: 311 LRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQ 370 Query: 538 LVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPV 597 L ++TM +FTC+A+HAA++ GQ D AW+PN P +M++PPPT+K T + +LP V Sbjct: 371 LCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDV 430 Query: 598 NATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQG 657 C + W LS+ D PLG + +++F+ P+ + F++ L ++ + I RN+ Sbjct: 431 RQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQ 490 Query: 658 LVLPYTYLDPPLIENSVS 675 L PY YL P IENSV+ Sbjct: 491 LDWPYEYLKPSCIENSVT 508 >5MEF-A nrPDB Length = 569 Score = 240 bits (613), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 185/579 (31%), Positives = 281/579 (48%), Gaps = 49/579 (8%) Query: 129 DHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLEL-NIKYSTAKNANFYLQ 187 D P Q+QR + ++E YQ+ L KT+ E+ ++KY ++ Sbjct: 9 DDTPDQQEQRNRAIAQQREAYQYSE----TAGILLIKTLPQSEMFSLKYLIERDKGLVSL 64 Query: 188 AGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLN 247 + A I+ + D + L + + +F P + F + D FA Q + G N Sbjct: 65 IANTLAS-NIENIFDP---FDKLEDFEEMFPLLPKPLVMNTFRN---DRVFARQRIAGPN 117 Query: 248 PVLIRRC-HYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI-------- 298 P++I R LP NFPVTDAM ++ +L + +G LF+ ++ L+ + Sbjct: 118 PMVIERVVDKLPDNFPVTDAMFQKIMFTKKTLAEAIAQGKLFITNYKGLAELSPGRYEYQ 177 Query: 299 QTNVINGKPQFSAAPMTLLYQSPGC-----GPLLPLAIQLSQTPGP-NSPIFLPTDDKWD 352 + + K + AAP+ L P G L P+AIQ++Q P P +PI+ P D K Sbjct: 178 KNGTLVQKTKTIAAPLVLYAWKPEGFGDYRGSLAPIAIQINQQPDPITNPIYTPRDGK-H 236 Query: 353 WLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHI 412 W +AK + + A+ + HEA++HL +HL+ E F LAT +L HPL LL PH ++TL I Sbjct: 237 WFIAKIFAQMADGNCHEAISHLARTHLILEPFVLATANELAPNHPLSVLLKPHFQFTLAI 296 Query: 413 NTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQL--NYSLLCLPEDIRTRGV----- 465 N LARE I G D +E +I+ +K+ N++ LP ++ RGV Sbjct: 297 NELAREQFISAGGYADDLLAGTLEASIAVIKAAIKEYMDNFTEFALPRELARRGVGIGDV 356 Query: 466 -----EDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGF 520 +P Y YRDD M +W A+E +V + + +YY S ++ D ELQ WVR + S Sbjct: 357 DQRGENFLPDYPYRDDAMLLWNAIEVYVRDYLSLYYQSPVQIRQDTELQNWVRRLVSPE- 415 Query: 521 LNQESSGIPSS--LETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPP 578 +G+ S+ L T EALV T VIF +HAAV+ Q+D A++PN+P + P Sbjct: 416 -GGRVTGLVSNGELNTIEALVAIATQVIFVSGPQHAAVNYPQYDYMAFIPNMPLATYATP 474 Query: 579 PTSKGLATCEGFIATLPPVN-ATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSI 637 P + + + LPP A + L L P LG YPD F + ++ + Sbjct: 475 PNKESNISEATILNILPPQKLAARQLELMRTLCVFYPNR---LG-YPDTEFVDVRAQQVL 530 Query: 638 ATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676 FQ RL +I + I N+ + PYTYL P + NS SI Sbjct: 531 HQFQERLQEIEQRIVLCNEKRLEPYTYLLPSNVPNSTSI 569 >4G32-A nrPDB Length = 688 Score = 224 bits (571), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 162/499 (32%), Positives = 234/499 (46%), Gaps = 34/499 (6%) Query: 200 LLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPK 259 L+ + G LN + +F R P +F ++D FA + G NP+LIRR LP Sbjct: 202 LVTQGGQGDGLNRFRAVFGTLRLPEVADSF---RDDEAFAYWRVAGPNPLLIRRVDALPA 258 Query: 260 NFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGIL-----SGIQTNVINGKPQFSAAPM 314 NFP+ + V+G SL L+L+D+ L SG ++ G F+ AP+ Sbjct: 259 NFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGT-GFAYAPI 317 Query: 315 TLLYQSPGCGPLLPLAIQLSQTPGPNSPIFL-----PTDDKWDWLLAKTWVRNAEFSFHE 369 L LLP+AIQ Q P + P+F+ +D W W +AKT V+ AE ++HE Sbjct: 318 ALFALGKDRAGLLPVAIQCGQDPATH-PMFVRPAESESDLYWGWQMAKTVVQVAEENYHE 376 Query: 370 ALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDR 429 HL +HL+ E F LAT R L HPL LL PH TL IN A +L+ +D Sbjct: 377 MFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFIDV 436 Query: 430 STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVED---IPGYYYRDDGMQIWGAVER 486 I+ N ++ LPE ++ R V+D +P Y YRDDG+ +W A+ + Sbjct: 437 MFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQ 496 Query: 487 FVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVI 546 + ++ + +YY SD V D EL AWV E+ G + +G + R LV+ +TMVI Sbjct: 497 WAADYVAVYYASDGDVTADVELAAWVGEVIGSG----KVAGF-RPITGRSQLVEVLTMVI 551 Query: 547 FTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILA 606 FT SA+HAAV+ Q + P + P P S + ++ +PP + + Sbjct: 552 FTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNI 611 Query: 607 LWLLSK----EPGDQRPLG-----TYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQG 657 LL GD R G + D T A + FQ+RL ++ I+ RNQ Sbjct: 612 YHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVT--ASGGPLERFQARLKEVEATIRTRNQA 669 Query: 658 LVLPYTYLDPPLIENSVSI 676 PY YL P I S +I Sbjct: 670 RRKPYEYLLPSRIPASTNI 688 >1RRL-A nrPDB Length = 857 Score = 181 bits (460), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 156/508 (30%), Positives = 243/508 (47%), Gaps = 71/508 (13%) Query: 232 WQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTS-------------- 277 W D FA + L G+NP LIR K+FP + + V G TS Sbjct: 358 WMTDEEFAREMLAGVNPNLIRCL----KDFPPRSKLDSQVYGDHTSQITKEHLEPNLEGL 413 Query: 278 -LQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS-- 334 + ++ LFL+DH IN + A T+L+ G L PLAI+LS Sbjct: 414 TVDEAIQNKRLFLLDHHDPIMPYLRRINATSTKAYATRTILFLK-NDGTLRPLAIELSLP 472 Query: 335 ----QTPGPNSPIFLPTDDKWD---WLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLA 387 G S +FLP D+ + WLLAK +V + +H+ ++H L++H + E F +A Sbjct: 473 HPQGDQSGAFSQVFLPADEGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIA 532 Query: 388 TLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMK 447 T R L HP++KLL PH R T++IN LAR L+ G V++++ G E+ K Sbjct: 533 TNRHLSVVHPIYKLLHPHYRDTMNINGLARLSLVNDGGVIEQTFLWGRYSV-EMSAVVYK 591 Query: 448 QLNYSLLCLPEDIRTRG--VED----------IPGYYYRDDGMQIWGAVERFVSEIIGIY 495 ++ LP D+ RG +ED I Y Y DG++IW A++ +V E + +Y Sbjct: 592 DWVFTDQALPADLIKRGMAIEDPSCPHGIRLVIEDYPYTVDGLEIWDAIKTWVHEYVFLY 651 Query: 496 YPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAA 555 Y SD+++++D ELQA +E+ G ++++ ++TRE LV+ ++I+T SA HAA Sbjct: 652 YKSDDTLREDPELQACWKELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTASALHAA 711 Query: 556 VSAGQFDSCAWMPNLPP-SMQLPPPTSKGLATCE--------GFIATLPPVNATCDVILA 606 V+ GQ+ + N P S + P KG A E ++ T+ P T + Sbjct: 712 VNFGQYPYGGLILNRPTLSRRFMP--EKGSAEYEELRKNPQKAYLKTITPKFQTLIDLSV 769 Query: 607 LWLLSKEPGDQRPLGTYPDEHFTEEA-PRRSIATFQSRLAQISRGIQERNQG-------- 657 + +LS+ D+ LG + ++T + + F ++LAQI + ERN Sbjct: 770 IEILSRHASDEVYLGERDNPNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNRCG 829 Query: 658 -LVLPYTYLDPPLIE--------NSVSI 676 + +PYT L P E NS+SI Sbjct: 830 PVQMPYTLLLPSSKEGLTFRGIPNSISI 857 >2IUJ-A nrPDB Length = 853 Score = 176 bits (447), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 146/507 (28%), Positives = 238/507 (46%), Gaps = 68/507 (13%) Query: 232 WQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGP---------------GT 276 W D FA + + GLNP +I+ + + FP++ + G G Sbjct: 353 WMTDEEFARETIAGLNPNVIK----IIEEFPLSSKLDTQAYGDHTCIITKEHLEPNLGGL 408 Query: 277 SLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS-- 334 +++ ++ LF++DH IN + A T+ + G L PLAI+LS Sbjct: 409 TVEQAIQNKKLFILDHHDYLIPYLRKINANTTKTYATRTIFFLK-NDGTLTPLAIELSKP 467 Query: 335 ----QTPGPNSPIFLPTDD---KWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLA 387 + GP S +++P+ + + WLLAK +V + +H+ ++H L++H + E F +A Sbjct: 468 HPQGEEYGPVSEVYVPSSEGVEAYIWLLAKAYVVVNDACYHQIISHWLNTHAVVEPFVIA 527 Query: 388 TLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMK 447 T R L HP++KLL PH R T++IN+LAR+ L+ +++++ G E+ K Sbjct: 528 TNRHLSVVHPIYKLLFPHYRDTMNINSLARKSLVNADGIIEKTFLWGRYSL-EMSAVIYK 586 Query: 448 QLNYSLLCLPEDIRTRGV--ED----------IPGYYYRDDGMQIWGAVERFVSEIIGIY 495 ++ LP D+ RGV +D I Y Y DG++IW A++ +V E + Y Sbjct: 587 DWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVEEYVSFY 646 Query: 496 YPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAA 555 Y SDE +Q D ELQAW +E+ G + + ++TRE LV+ +I+ SA HAA Sbjct: 647 YKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASATLIWIASALHAA 706 Query: 556 VSAGQFDSCAWMPNLPP-SMQLPP----PTSKGLATC--EGFIATLPPVNATCDVILALW 608 V+ GQ+ + N P S + P P LA + F+ T+ T + + Sbjct: 707 VNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLIDLTIIE 766 Query: 609 LLSKEPGDQRPLGTYP-DEHFTEEA-PRRSIATFQSRLAQISRGIQERNQGLVL------ 660 +LS+ D+ LG +++T +A P + F L +I + + E+N L Sbjct: 767 ILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKNLEEIEKKLIEKNNDETLRNRYGP 826 Query: 661 ---PYTYLDPPL--------IENSVSI 676 PYT L P I NS+SI Sbjct: 827 AKMPYTLLYPSSEEGLTFRGIPNSISI 853 >2IUK-A nrPDB Length = 864 Score = 172 bits (435), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 144/482 (29%), Positives = 226/482 (46%), Gaps = 54/482 (11%) Query: 235 DAFFASQFLNGLNPVLIRRCHYLP------------KNFPVTDAMVASVLGPGTSLQAEL 282 D FA + + G+NP +IRR P + +T + +G G +++ L Sbjct: 367 DEEFAREVIAGVNPNVIRRLQEFPPKSTLDPTLYGDQTSTITKEQLEINMG-GVTVEEAL 425 Query: 283 EKGSLFLVDHGILSGIQTNVINGKPQFSA-APMTLLYQSPGCGPLLPLAIQLSQ------ 335 LF++D+ IN P A A T+L+ G L PLAI+LS+ Sbjct: 426 STQRLFILDYQDAFIPYLTRINSLPTAKAYATRTILFLKDD-GTLKPLAIELSKPHPDGD 484 Query: 336 TPGPNSPIFLPTDDKWD---WLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQL 392 GP S + LP + D WLLAK V + +H+ ++H L++H + E F +AT R L Sbjct: 485 NLGPESIVVLPATEGVDSTIWLLAKAHVIVNDSGYHQLVSHWLNTHAVMEPFAIATNRHL 544 Query: 393 PHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYS 452 HP++KLL PH R T++IN LAR+ LI ++++S G E+ K ++ Sbjct: 545 SVLHPIYKLLYPHYRDTININGLARQSLINADGIIEKSFLPGKYSI-EMSSSVYKNWVFT 603 Query: 453 LLCLPEDIRTRG--VED----------IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDE 500 LP D+ RG +ED I Y Y DG++IW A++ +V E + +YYP+D Sbjct: 604 HQALPADLVKRGLAIEDPSAPHGLRLVIEDYPYAVDGLEIWDAIKTWVHEYVSLYYPTDA 663 Query: 501 SVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQ 560 +VQ D ELQAW +E KG + + +T E L+Q +++++T SA HAAV+ GQ Sbjct: 664 AVQQDTELQAWWKEAVEKGHGDLKEKPWWPKKQTTEDLIQSCSIIVWTASALHAAVNFGQ 723 Query: 561 FDSCAWMPNLP-------PSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKE 613 + + N P P+ P + ++ T+ P T + + +LS+ Sbjct: 724 YPYGGLILNRPTLARRFIPAEGTPEYDEMVKNPQKAYLRTITPKFETLIDLSVIEILSRH 783 Query: 614 PGDQRPLGTYPDEHF-TEEAPRRSIATFQSRLAQISRGIQERNQG---------LVLPYT 663 D+ LG ++ T++ + F S+L I I RN + LPYT Sbjct: 784 ASDEIYLGERETPNWTTDKKALEAFKRFGSKLTGIEGKINARNSDPSLRNRTGPVQLPYT 843 Query: 664 YL 665 L Sbjct: 844 LL 845 >4WFO-A nrPDB Length = 858 Score = 162 bits (410), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 150/533 (28%), Positives = 245/533 (45%), Gaps = 67/533 (12%) Query: 204 KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPV 263 K L+R+ + + I F + + + W D FA + + G+NP +IR P + Sbjct: 333 KELYRT--DGQHILKFPQPHVVQVSQSAWMTDEEFAREMIAGVNPCVIRGLEEFPPKSNL 390 Query: 264 TDAMVA---------SVLGPGTSLQAELEKGSLFLVD-HGILSGI--QTNVINGKPQFSA 311 A+ S+ G ++ L LF++D H I Q N +N ++ Sbjct: 391 DPAIYGDQSSKITADSLDLDGYTMDEALGSRRLFMLDYHDIFMPYVRQINQLNSAKTYAT 450 Query: 312 APMTLLYQSPGCGPLLPLAIQLS------QTPGPNSPIFLPTDDKWD---WLLAKTWVRN 362 + L + G L P+AI+LS S + LP + + WLLAK +V Sbjct: 451 RTILFLRED---GTLKPVAIELSLPHSAGDLSAAVSQVVLPAKEGVESTIWLLAKAYVIV 507 Query: 363 AEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIV 422 + +H+ ++H L++H E F +AT R L HP++KLL PH R ++IN LAR+ LI Sbjct: 508 NDSCYHQLMSHWLNTHAAMEPFVIATHRHLSVLHPIYKLLTPHYRNNMNINALARQSLIN 567 Query: 423 PGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGV--ED----------IPG 470 +++ +T + + E+ K ++ LP D+ RGV +D I Sbjct: 568 ANGIIE-TTFLPSKYSVEMSSAVYKNWVFTDQALPADLIKRGVAIKDPSTPHGVRLLIED 626 Query: 471 YYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPS 530 Y Y DG++IW A++ +V E + +YY D+ V++D ELQ W +E KG + + Sbjct: 627 YPYAADGLEIWAAIKTWVQEYVPLYYARDDDVKNDSELQHWWKEAVEKGHGDLKDKPWWP 686 Query: 531 SLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGF 590 L+T E LV+ ++I+ SA HAAV+ GQ+ + N P + + P KG E Sbjct: 687 KLQTLEDLVEVCLIIIWIASALHAAVNFGQYPYGGLIMNRPTASRRLLP-EKGTPEYEEM 745 Query: 591 I-----ATLPPVNATCDVILALW---LLSKEPGDQRPLGTYPDEHFTEEAPR-RSIATFQ 641 I A L + + +++L +LS D+ LG + H+T ++ ++ F Sbjct: 746 INNHEKAYLRTITSKLPTLISLSVIEILSTHASDEVYLGQRDNPHWTSDSKALQAFQKFG 805 Query: 642 SRLAQISRGIQERN-----QG-----LVLPYTYLDPPL--------IENSVSI 676 ++L +I + RN QG + LPYT L P I NS+SI Sbjct: 806 NKLKEIEEKLVRRNNDPSLQGNRLGPVQLPYTLLYPSSEEGLTFRGIPNSISI 858 >6NS2-A nrPDB Length = 769 Score = 136 bits (342), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 127/440 (28%), Positives = 197/440 (44%), Gaps = 73/440 (16%) Query: 229 FEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLF 288 ++ W DA FA Q +G+NP I +++A + ++A LE G Sbjct: 260 YDDWYSDARFAQQHFSGVNPSTIETASQDKIKEYISEAQKQGL----DKVKAILEDGKDI 315 Query: 289 LV-DHGIL---SGIQTNVINGKPQFS--------------AAPMTLLYQSPGCGPLLPLA 330 L+ D+ +G I + AA +++Q G L PLA Sbjct: 316 LIQDYSYFREATGATNEQIFQNTVYELKGTTPTGKTTSRYAAASVVIFQLHEDGRLHPLA 375 Query: 331 IQLSQTPGPNSPIFL------PTD-------DKWDWLLAKTWVRNAEFSFHEALTHLLHS 377 I L ++ I + P D + W W AKT + A+++ HE THL+ + Sbjct: 376 ITLDYKGSLDNSITIFNRRLSPDDTCDIAEKEDWPWRYAKTVAQTADWARHEVATHLVDT 435 Query: 378 HLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIG--- 434 H++ E +AT R +P L+++L PH TL +N AR+LL VPG V+ R G G Sbjct: 436 HMIEEAIIVATNRIIPEGELLYEILSPHWFRTLSLNAAARKLL-VPG-VIARIAGFGPTS 493 Query: 435 ----IEGFS--ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPG--------YYYRDDGMQI 480 +G + +LI + K N+ +P D++ RG DI G Y Y +D + Sbjct: 494 PSLDFKGNNAFKLIDWSYKNFNFQDKYIPNDLKKRGF-DIKGDKSGKYKNYPYANDMYLL 552 Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPS--SLETREAL 538 WG + FV +I Y SD VQ D + W +EI Q + IP+ ++ T E L Sbjct: 553 WGIIRNFVKTVIESQYTSDHVVQKDPYIGGWCKEI-------QTNGQIPTFPTITTVEQL 605 Query: 539 VQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGF-----IAT 593 + VTM I T S +H AV+ Q +++P PP++ P P + L+ +G+ A Sbjct: 606 IDAVTMCIHTASPQHTAVNYLQDYYYSFVPAKPPALCTPLP--QDLSALQGYTEKDLTAA 663 Query: 594 LPPVNATCDVILALWLLSKE 613 LP T D+ WLL+ + Sbjct: 664 LPI--GTEDMKWKDWLLAAQ 681 >5FNO-A nrPDB Length = 605 Score = 124 bits (311), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 138/529 (26%), Positives = 229/529 (43%), Gaps = 60/529 (11%) Query: 186 LQAGSAFAEM-KIKGLLDRKGLWRSLNEMKRIFNFRRTPA-----AEHAFEHWQEDAFFA 239 +Q+ AF + K+ + + G SL++ K ++ + A E++ D F+ Sbjct: 99 VQSLRAFTDAAKVAANIKQNGGLNSLDDFKVLYQDGWKGSVPQGIARGQSENYTSDLLFS 158 Query: 240 SQFLNGLNPVLIRRCH----YLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGIL 295 + L+ +NP +++R H LP F V A V + TSL+A G LF+ DH Sbjct: 159 MERLS-VNPYILKRLHPTEDALP--FQVDRATVKQLTK--TSLKALHAAGRLFVADHSY- 212 Query: 296 SGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQ------LSQTPGPNSPIFLPTDD 349 Q N ++SAA L Y P LPLAI+ L+ TP L TD+ Sbjct: 213 ---QRNYTRLANRYSAACTALFYLDPRSNQFLPLAIKTNVGADLTYTP-------LDTDN 262 Query: 350 KWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYT 409 +WLLAK N + FH + H+ + H + E+ LA LR + HP+ L+ Sbjct: 263 N-NWLLAKIMFNNNDL-FHGQIFHVAYPHAIAEIVHLAALRTMSARHPVLALMERLMYQA 320 Query: 410 LHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLN-YSLLCLPEDIRTRGVED- 467 + L +L G + +++ + + + + + L D+R RG+ D Sbjct: 321 YAVRPLGERVLFNKGGLFEQNFAYPQDMVYKFVGDSYPTTGRWRAGYLDTDVRARGLVDA 380 Query: 468 -----IPGYYYRDDGMQIWGAVERFVSEII-GIYYPSDESVQDDRELQAWVREIFSKGFL 521 +P + + +DG ++ + RFV + Y+ SDE V D ELQAWV E + Sbjct: 381 DYGPELPHFPFYEDGSRLVEVIRRFVRSFVDATYHESDEMVAKDAELQAWVAEANGPAGV 440 Query: 522 NQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQ-FDSCAWMPNLPPSMQLPPPT 580 P L+TRE LV+ +T + + H ++ G+ + +P P ++ P PT Sbjct: 441 EDFE---PGPLDTRERLVEVLTHMAWLTGCAHHVLNQGEPVTASGVLPMHPTALYAPVPT 497 Query: 581 SKGLATCEGFIATLPPVNATCDVILALWLLSKE---PGDQ--RPLGTYPDEHFTE-EAPR 634 SK T + + LP + D + L ++ P +Q R + P EA R Sbjct: 498 SKANTTAD-LLGYLPSAQKSVDQVTLLARFNRPDVVPTNQTLRYMFAAPQLLLGNGEAYR 556 Query: 635 RSIATFQSRLAQISRGIQER-------NQGLVLPYTYLDPPLIENSVSI 676 R+ F + +IS ++ R +QG+ + LDP I +S+ Sbjct: 557 RANQRFVRAMGRISDEVKARRFDDRGLSQGMPFIWQALDPGNIPFYLSV 605 >5FX8-A nrPDB Length = 618 Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 138/556 (24%), Positives = 227/556 (40%), Gaps = 89/556 (16%) Query: 166 TVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAA 225 + D+ L + + + A Y +A FA++ +G +++L++ ++N Sbjct: 93 SARDVLLWRQDAANQTATAYREANETFADIT------SRGGFKTLDDFALLYN------- 139 Query: 226 EHAFEHWQE----------------DAFFASQFLNGLNPVLIRRCHYLPKNFPVT-DAMV 268 HW+E D F+ + L+ NP +++R H P + ++ V Sbjct: 140 ----GHWKESVPEGISKGMLSNCTSDLLFSMERLSS-NPYVLKRLHPTKDKLPFSVESKV 194 Query: 269 ASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLP 328 L T+L+A + G LFLVDH Q +++AA L Y LP Sbjct: 195 VKKL-TATTLEALHKGGRLFLVDHSY----QKKYTPQPGRYAAACQGLFYLDARSNQFLP 249 Query: 329 LAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLAT 388 LAI+ T + P DDK DWLLAK N + F+ + H+L H +PE+ A Sbjct: 250 LAIK---TNVGVDLTYTPLDDKDDWLLAKIMFNNNDL-FYSQMYHVLF-HTIPEIVHEAA 304 Query: 389 LRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTG------IGIEGFSELI 442 R L HP+ +L I + +L PG D++ G I G Sbjct: 305 FRTLSDRHPVMGVLNRLMYQAYAIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQ 364 Query: 443 QRNMKQLNYSLLCLPEDIRTRGV--ED----IPGYYYRDDGMQIWGAVERFVSEIIGIYY 496 Q Y L +D+R+RG+ ED +P + + +D ++ GA+ RF+ + Y Sbjct: 365 GGGGFQAGY----LEKDLRSRGLIGEDSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTY 420 Query: 497 PSDE----SVQDDRELQAWVREIFSKGFLNQESSGIPSS-LETREALVQYVTMVIFTCSA 551 +D+ ++ D ELQ W+ E + P++ L R LV +T V + Sbjct: 421 GADDGDDGALLRDYELQNWIAEANGPA----QVRDFPAAPLRRRAQLVDVLTHVAWITGG 476 Query: 552 KHAAVSAGQ-FDSCAWMPNLPPSMQLPPPTSKGL---ATCEGFIATLPPVNATCDVILAL 607 H ++ G +P P ++ P PT+KG T G +A LP + + L Sbjct: 477 AHHVMNQGSPVKFSGVLPLHPAALYAPIPTAKGATGNGTRAGLLAWLPNERQAVEQVSLL 536 Query: 608 WLLSK-EPGDQ----RPLGTYPDEHFTEEAPRRSIAT--FQSRLAQISRGIQER------ 654 ++ + GD+ R PD P + A F +ISR I R Sbjct: 537 ARFNRAQVGDRKQTVRDAFAAPDL-LAGNGPGYAAANARFVEDTGRISREIAGRGFDGKG 595 Query: 655 -NQGLVLPYTYLDPPL 669 +QG+ +T L+P + Sbjct: 596 LSQGMPFVWTALNPAV 611 >5EK8-A nrPDB Length = 668 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 37/197 (18%) Query: 233 QEDAFFASQFLNGLNPVLIRRCHYLPKNFPVT---DAMVASVLGPGTSLQAE--LEKGSL 287 + D +F + LNG+NP L++R P F ++ D +++A L+ G L Sbjct: 245 RSDEYFVLRVLNGMNPCLLKRSKSDPNQFKMSFIWDNYEKDTEHDLHNVEAYFVLKDGKL 304 Query: 288 FLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPT 347 F P + QS L P +P + ++ P Sbjct: 305 F------------------------PTMITIQSRYPDSLAP------HSPLKDREVYTPN 334 Query: 348 DDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTR 407 D + WL AK R A EA+ H +H+ E + +A R L +P+ +L PH + Sbjct: 335 DGE-KWLQAKRIFRTAALFDGEAIEHYAKAHVQMEQYAVACFRNL-RKNPIRLMLTPHLK 392 Query: 408 YTLHINTLARELLIVPG 424 ++IN +LL+ P Sbjct: 393 SIININRRGDDLLVEPN 409 >1Y1X-A nrPDB Length = 191 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 9/57 (15%) Query: 493 GIYYPSDESVQDDRELQAWVREIFSKGF-------LNQ--ESSGIPSSLETREALVQ 540 G+Y PS + D++EL W R + + G LN S+G+P SL T E L+ Sbjct: 14 GVYAPSARHMNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLH 70 >4FGZ-A nrPDB Length = 266 Score = 32.7 bits (73), Expect = 0.53, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 2/58 (3%) Query: 92 FQLTPPRGGHLLFPCYQWLEGAGTLVLQE--GTAKVSWADHHPVLQQQRQEELQARQE 147 L+ L CY+WL+ GTL++ + T K +W D +QR+ L +E Sbjct: 131 LHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEE 188 >2VD3-A nrPDB Length = 289 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 9/57 (15%) Query: 422 VPGQVVDRSTGIGIEGFSELIQRN-----MKQLNYS----LLCLPEDIRTRGVEDIP 469 +P V D + +GI G+ +++R ++ L Y +L PED RG EDIP Sbjct: 57 IPEFVADGAADLGITGYDLIVERGSDVEILEDLKYGRASLVLAAPEDSTIRGPEDIP 113 >1QO0-A nrPDB Length = 385 Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 35/90 (38%) Query: 397 PLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCL 456 PL LL T T I R ++ + ++R G+G L Q + LC Sbjct: 8 PLIGLLFSETGVTADIERSQRYGALLAVEQLNREGGVGGRPIETLSQDPGGDPDRYRLCA 67 Query: 457 PEDIRTRGVEDIPGYYYRDDGMQIWGAVER 486 + IR RGV + G Y + VER Sbjct: 68 EDFIRNRGVRFLVGCYMSHTRKAVMPVVER 97 >4KC3-B nrPDB Length = 309 Score = 29.6 bits (65), Expect = 4.6, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 8/74 (10%) Query: 296 SGIQTNVINGKPQFSA---APMTLLYQSPGCGPLLPLAIQLSQTPGP--NSPIFLPTDDK 350 SGI T ++ P F+ A +T+ + C +P + S G NS I+ PT D Sbjct: 64 SGIYTCIVRS-PTFNRTGYANVTIYKKQSDCN--VPDYLMYSTVSGSEKNSKIYCPTIDL 120 Query: 351 WDWLLAKTWVRNAE 364 ++W W +N + Sbjct: 121 YNWTAPLEWFKNCQ 134 >2KD3-A nrPDB Length = 113 Score = 29.3 bits (64), Expect = 5.6, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 2/54 (3%) Query: 300 TNVINGKPQFSAAPMTLLYQSPGCGP--LLPLAIQLSQTPGPNSPIFLPTDDKW 351 T + P SA P+T L S CGP LLP AI + PN P F D++ Sbjct: 30 TRFLTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRY 83 >5Z57-K nrPDB Length = 225 Score = 29.3 bits (64), Expect = 6.4, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Query: 141 ELQARQEMYQWKAYNPGWPHCLD--EKTVEDLELNIKYSTAKNANFYLQAGSAFAEMK 196 EL ++ WK YN H ++ +K ++ L +I+ + N L AGS EM+ Sbjct: 125 ELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREME 182 >5DWN-A nrPDB Length = 187 Score = 28.9 bits (63), Expect = 8.7, Method: Compositional matrix adjust. Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 15/95 (15%) Query: 32 ESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRW 91 E P +D + K F A A++ F + + E GRVL V P LA D+ + Sbjct: 39 EIEPPTMDEMAKRFAAFADQGFPILVAEADGRVLGYAYASYFRVRPAYRWLAEDSIY--- 95 Query: 92 FQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVS 126 + P G +G G L+L+E A++S Sbjct: 96 --IAPDAKG----------QGIGKLLLRELIARIS 118 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4NRE-A nrPDB 947 0.0 3O8Y-A nrPDB 876 0.0 2P0M-A nrPDB 857 0.0 2FNQ-A nrPDB 838 0.0 3VF1-A nrPDB 819 0.0 3RDE-A nrPDB 728 0.0 3D3L-A nrPDB 649 0.0 1RRL-A nrPDB 553 e-158 5MEF-A nrPDB 553 e-157 4WFO-A nrPDB 538 e-153 2IUJ-A nrPDB 531 e-151 2IUK-A nrPDB 525 e-149 4G32-A nrPDB 502 e-142 5FNO-A nrPDB 458 e-129 5FX8-A nrPDB 450 e-127 6NS2-A nrPDB 374 e-104 5EK8-A nrPDB 176 3e-44 Sequences not found previously or not previously below threshold: 1KHO-A nrPDB 46 5e-05 2WXU-A nrPDB 45 1e-04 1OLP-A nrPDB 44 3e-04 5ZCR-A nrPDB 35 0.11 5M1Z-A nrPDB 33 0.37 5A01-A nrPDB 32 0.92 4R1D-A nrPDB 31 1.8 5WYK-BB nrPDB 30 2.5 4GRX-A nrPDB 30 2.5 2DEP-A nrPDB 30 4.6 4FGZ-A nrPDB 30 4.7 6BHR-G nrPDB 29 5.4 4E3Q-A nrPDB 29 5.9 4MOP-A nrPDB 29 7.1 5TEO-A nrPDB 29 8.2 5O2U-A nrPDB 29 8.2 2OWC-A nrPDB 29 8.8 >4NRE-A nrPDB Length = 696 Score = 947 bits (2448), Expect = 0.0, Method: Composition-based stats. Identities = 676/676 (100%), Positives = 676/676 (100%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED Sbjct: 21 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 80 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE Sbjct: 81 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 140 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK Sbjct: 141 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 200 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS Sbjct: 201 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 260 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT Sbjct: 261 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 320 Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 360 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV Sbjct: 321 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV 380 Query: 361 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 420 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL Sbjct: 381 RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL 440 Query: 421 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 480 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI Sbjct: 441 IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI 500 Query: 481 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 540 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ Sbjct: 501 WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ 560 Query: 541 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 600 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT Sbjct: 561 YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT 620 Query: 601 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 660 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL Sbjct: 621 CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL 680 Query: 661 PYTYLDPPLIENSVSI 676 PYTYLDPPLIENSVSI Sbjct: 681 PYTYLDPPLIENSVSI 696 >3O8Y-A nrPDB Length = 691 Score = 876 bits (2263), Expect = 0.0, Method: Composition-based stats. Identities = 287/681 (42%), Positives = 423/681 (62%), Gaps = 15/681 (2%) Query: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60 M + V V+TG AGT D + +S+VG+ G S LD F GA + + VT+ E+ Sbjct: 21 MPSYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDK--GSFERGAVDSYDVTVDEE 78 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 +G + L+R+ K + D W+ ++ L P G ++ FPCY+W+ G +VL++ Sbjct: 79 LGEIQLVRIEKRK-------YGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRD 131 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ + K Sbjct: 132 GRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEK 191 Query: 181 NANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239 +F L A + I + + W + ++IF +E HWQED F Sbjct: 192 GVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFG 251 Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299 QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI Sbjct: 252 YQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGID 311 Query: 300 TNVI-NGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKT 358 N QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK Sbjct: 312 ANKTDPCTLQFLAAPICLLYKNL-ANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKI 370 Query: 359 WVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARE 418 WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FKLL+ H R+T+ INT ARE Sbjct: 371 WVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKARE 430 Query: 419 LLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGV---EDIPGYYYRD 475 LI + D++ G G +++QR MK L Y+ LC PE I+ RG+ EDIP Y+YRD Sbjct: 431 QLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRD 490 Query: 476 DGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETR 535 DG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++R Sbjct: 491 DGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSR 550 Query: 536 EALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLP 595 E L +Y+T+VIFT SA+HAAV+ GQ+D +W+PN PP+M+ PPPT+KG+ T E + TLP Sbjct: 551 EQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLP 610 Query: 596 PVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERN 655 +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ERN Sbjct: 611 DRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERN 670 Query: 656 QGLVLPYTYLDPPLIENSVSI 676 + L LPY YL P I NSV+I Sbjct: 671 ENLQLPYYYLSPDRIPNSVAI 691 >2P0M-A nrPDB Length = 662 Score = 857 bits (2213), Expect = 0.0, Method: Composition-based stats. Identities = 251/679 (36%), Positives = 377/679 (55%), Gaps = 25/679 (3%) Query: 4 FRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEF--TAGAEEDFQVTLPEDV 61 +RV VSTG + AG+ +KV + +VG GE LG T EE+F+V + + + Sbjct: 3 YRVCVSTGASIYAGSKNKVELWLVGQHGEV------ELGSCLRPTRNKEEEFKVNVSKYL 56 Query: 62 GRVLLLRVHKAPPVLPLLGPLAPDAWFCRWF--QLTPPRGGHLLFPCYQWLEGAGTLVLQ 119 G +L +R+ K L DAWFC W Q FPCY+W+ G G L Sbjct: 57 GSLLFVRLRKK-------HFLKEDAWFCNWISVQALGAAEDKYWFPCYRWVVGDGVQSLP 109 Query: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179 GT + D + Q+ R++EL+ R+++YQW ++ G + + DL ++ ++ Sbjct: 110 VGTGCTTVGDPQGLFQKHREQELEERRKLYQWGSWKEGLILNVAGSKLTDLPVDERFLED 169 Query: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239 K +F AE+ +K L+ W++L++ RIF R+ A + WQED+ F Sbjct: 170 KKIDFEASLAWGLAELALKNSLNILAPWKTLDDFNRIFWCGRSKLARRVRDSWQEDSLFG 229 Query: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299 QFLNG NP+L+RR LP M L+ EL+ G+LF D +L I+ Sbjct: 230 YQFLNGANPMLLRRSVQLPARLVFPPGMEEL----QAQLEKELKAGTLFEADFALLDNIK 285 Query: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP--IFLPTDDKWDWLLAK 357 NVI Q+ AAP+ +L P G L+P+ IQL +SP +FLPTD WLLAK Sbjct: 286 ANVILYCQQYLAAPLVMLKLQPD-GKLMPMVIQLHLPKIGSSPPPLFLPTDPPMVWLLAK 344 Query: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 417 WVR+++F HE +HLL HL+ EVFT+AT+R LP HP+FKL++PH RYTL IN AR Sbjct: 345 CWVRSSDFQVHELNSHLLRGHLMAEVFTVATMRCLPSIHPVFKLIVPHLRYTLEINVRAR 404 Query: 418 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDG 477 L+ + D+ G G +L+Q+ L Y C P+D+ RG+ + +Y D Sbjct: 405 NGLVSDFGIFDQIMSTGGGGHVQLLQQAGAFLTYRSFCPPDDLADRGLLGVESSFYAQDA 464 Query: 478 MQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREA 537 +++W + R+V I+G+YY +DE+V+DD ELQ+W REI G + G P+SL++ Sbjct: 465 LRLWEIISRYVQGIMGLYYKTDEAVRDDLELQSWCREITEIGLQGAQKQGFPTSLQSVAQ 524 Query: 538 LVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPV 597 +VTM IFTC+ +H+++ GQ D W+PN P +M+LPPPT+K AT E +ATLP + Sbjct: 525 ACHFVTMCIFTCTGQHSSIHLGQLDWFTWVPNAPCTMRLPPPTTKD-ATLETVMATLPNL 583 Query: 598 NATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQG 657 + + + +W L ++ PLG + +E+F+ PR + F+ LA + + I+ RN+ Sbjct: 584 HQSSLQMSIVWQLGRDQPIMVPLGQHQEEYFSGPEPRAVLEKFREELAIMDKEIEVRNEK 643 Query: 658 LVLPYTYLDPPLIENSVSI 676 L +PY YL P ++ENSV+I Sbjct: 644 LDIPYEYLRPSIVENSVAI 662 >2FNQ-A nrPDB Length = 699 Score = 838 bits (2164), Expect = 0.0, Method: Composition-based stats. Identities = 233/700 (33%), Positives = 381/700 (54%), Gaps = 32/700 (4%) Query: 2 AEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPED 60 A + V V TG+ AGT +++ I G +G + L LD +F AG++E + V D Sbjct: 7 AIYNVEVETGDREHAGTDATITIRITGAKGRTDYLKLDKWFHNDFEAGSKEQYTVQ-GFD 65 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE 120 VG + L+ +H PD + R ++ + FPC++W+ +VL Sbjct: 66 VGDIQLIELHSDGGG---YWSGDPDWFVNRVIIISSTQDRVYSFPCFRWV--IKDMVLFP 120 Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 G A + + + ++ +QRQ+EL+ R+ YQW + P + KT +DL +++++ K Sbjct: 121 GEATLPFNEVPAIVSEQRQKELEQRKLTYQWDYVSDDMPGNIKAKTHDDLPRDVQFTDEK 180 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 + ++ +A + I L W S ++ ++ + + W ED +F Sbjct: 181 SRSYQESRKAALVNLGIGSLFTMFENWDSYDDYHILYRNWILGGTPNMADRWHEDRWFGY 240 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNG NPV++ RC LP NFPVT+ V + L G +L E++ G +++VD +L G ++ Sbjct: 241 QFLNGANPVILTRCDALPSNFPVTNEHVNASLDRGKNLDEEIKDGHIYIVDFKVLVGAKS 300 Query: 301 NVIN-----------------GKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPI 343 ++ AAP+ L Y + G L+P+AIQ++Q PGP +PI Sbjct: 301 YGGPVLEDIGYKVPDHLKHDEADIRYCAAPLALFYVNK-LGHLMPIAIQINQEPGPENPI 359 Query: 344 FLP-TDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLL 402 + P +++ DW++AK W+ AE +FH+ THLL +HL E F L+T R L HP+FKLL Sbjct: 360 WTPHEENEHDWMMAKFWLGVAESNFHQLNTHLLRTHLTTESFALSTWRNLASAHPVFKLL 419 Query: 403 IPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRT 462 PH L I+T+ R+ LI G +VD+S +G G +++ K++N LP ++ Sbjct: 420 QPHIYGVLAIDTIGRKELIGSGGIVDQSLSLGGGGHVTFMEKCFKEVNLQDYHLPNALKK 479 Query: 463 RGVED---IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKG 519 RGV+D +PG+YYRDDG+ +W A+E F+ EII I+Y +D+ V+ D E+Q+W+ ++ G Sbjct: 480 RGVDDPSKLPGFYYRDDGLALWEAIETFIGEIIAIFYKNDDDVKRDNEIQSWIYDVHKNG 539 Query: 520 FL---NQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQL 576 + + G+P+S E+RE L + +T ++FT S +HAAV+ Q D + PN P ++ Sbjct: 540 WRVNPGHQDHGVPASFESREQLKEVLTSLVFTFSCQHAAVNFSQKDHYGFTPNAPAVLRH 599 Query: 577 PPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRS 636 PPP KG AT + ++TLP + I +++L+K D+R LG Y + ++ + Sbjct: 600 PPPKKKGEATLQSILSTLPSKSQAAKAIATVYILTKFSEDERYLGNYSATAWEDKDALDA 659 Query: 637 IATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676 I FQ +L IS+ I++RN+ L +PY YL P I N +I Sbjct: 660 INRFQDKLEDISKKIKQRNENLEVPYIYLLPERIPNGTAI 699 >3VF1-A nrPDB Length = 698 Score = 819 bits (2116), Expect = 0.0, Method: Composition-based stats. Identities = 225/688 (32%), Positives = 377/688 (54%), Gaps = 24/688 (3%) Query: 3 EFRVRVSTGEAFGAGTWDKVSVSIVGTRG-ESPPLPLDN-LGKEFTAGAEEDFQVTLPED 60 ++++ V TG+ GAGT VS+ + G G E+ LD +F +G + + + D Sbjct: 21 KYKITVETGDLRGAGTDASVSIKLTGKDGAETSAFSLDKYFHNDFESGGTDTYDQS-GVD 79 Query: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWF--QLTPPRG--GHLLFPCYQWLEGAGTL 116 VG + ++ + + L D + + ++ G +FPCY+W+ L Sbjct: 80 VGEIAMITLKENGFG------LKSDWYIAKVIIEKIDEATGFSNKYIFPCYRWV--IKQL 131 Query: 117 VLQEGTAKVS-WADHHPVLQQQRQEELQARQEMYQWKA---YNPGWPHCLDEKTVEDLEL 172 V+ EG A + D+ + +QR +E+ +++Y+W Y P +D + + L Sbjct: 132 VVYEGKAILPNSKDNVKTIAEQRTKEVSENKKLYKWGTDPRYVQDLPGFVDAEEPKSLPK 191 Query: 173 NIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHW 232 +++++ ++ + + FA + + L W L + +++ HA E+W Sbjct: 192 DVQFTDEATSSLFRVGLADFANLGLSHLFGIWDDWDCLEDFRQLITPAIKSGLPHAAEYW 251 Query: 233 QEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDH 292 ++D +F SQFLNG NP +IRRC LP+NFPV + MV +L G +L+ +++G +F+ D+ Sbjct: 252 RDDVWFGSQFLNGSNPEVIRRCDKLPENFPVKNEMVEKLLDRGYTLEKAMKEGLIFITDY 311 Query: 293 GILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLP-TDDKW 351 IL GI T ++ P+ L Y ++P+AIQL Q PG N+ I+ P D +W Sbjct: 312 KILEGIPTMDTPEDKRYITTPLGLFYLKNNDD-IIPIAIQLYQQPGENNSIWTPLKDTEW 370 Query: 352 DWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLH 411 DW++AK W+R A+ +H+ +THLL HL+ E +++ R LP HP++KLL PHT+ + Sbjct: 371 DWIMAKLWLRCADTQYHQMITHLLRCHLMMEPTAVSSWRNLPSVHPVWKLLYPHTKGIMA 430 Query: 412 INTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGY 471 INTL R LI G D+ IG G L+Q++ + + + L +D+R RGV+ + + Sbjct: 431 INTLGRNDLIPTGGAADKVLSIGGGGQVTLMQKHYRSVTFDSYDLVKDLRQRGVDGLRKF 490 Query: 472 YYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGF---LNQESSGI 528 YY+DD + +W + +FV +II IYY D+SV+ D E+Q W+R++ G+ + + Sbjct: 491 YYKDDALLLWNVIHQFVQDIIQIYYNDDDSVKKDNEIQDWIRDLHENGYPAGSDGTDKKV 550 Query: 529 PSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCE 588 P S E RE LV ++T+V+FTCS +HAAV+ Q + + PN P M+ PPPT KG + + Sbjct: 551 PKSFENREELVHFLTVVVFTCSCQHAAVNFSQMATYGFHPNSPTLMRQPPPTEKGKSNHK 610 Query: 589 GFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQIS 648 +A+L + ++ + L+ ++ LG Y D F + A ++A F+S LA I+ Sbjct: 611 VIMASLANKHQAVTMVSVVNALTTIYPTEKFLGDYADNLFGDAAAHAAMAKFKSNLANIT 670 Query: 649 RGIQERNQGLVLPYTYLDPPLIENSVSI 676 + I ERNQG+V PYT+L P + NS++I Sbjct: 671 KQITERNQGMVSPYTWLIPGHVPNSIAI 698 >3RDE-A nrPDB Length = 573 Score = 728 bits (1880), Expect = 0.0, Method: Composition-based stats. Identities = 211/558 (37%), Positives = 309/558 (55%), Gaps = 8/558 (1%) Query: 121 GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK 180 GTA+ D + ++ R+EEL R+++Y+W + G + + DL ++ ++ K Sbjct: 22 GTARTVVDDPQGLFKKHREEELAERRKLYRWGNWKDGLILNIASTGIHDLPVDERFLEDK 81 Query: 181 NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS 240 +F A++ +K L+ W SL+ RIF ++ AE + W+EDA F Sbjct: 82 RIDFEASLAKGLADLAVKDSLNVLMSWNSLDSFNRIFWSGQSKLAERVRDSWKEDALFGY 141 Query: 241 QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT 300 QFLNG NP+L+R LP M L+ EL+ G+LF D +L GI+ Sbjct: 142 QFLNGTNPMLLRHSVELPARLKFPPGMEEL----QAQLEKELQGGTLFEADFSLLDGIKA 197 Query: 301 NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS--QTPGPNSPIFLPTDDKWDWLLAKT 358 NVI Q+ A P+ +L P G LLP+ IQL + P P+FLPTD WLLAK Sbjct: 198 NVILSSQQYLAVPLVMLKLQPD-GKLLPMVIQLQLPREGSPLPPLFLPTDPPMVWLLAKC 256 Query: 359 WVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARE 418 WVR+++F HE +HLL HL+ EV +AT+R LP HP+FKLLIPH RYT+ IN AR Sbjct: 257 WVRSSDFQLHELHSHLLRGHLMAEVIAVATMRCLPSIHPIFKLLIPHFRYTMEINVRARN 316 Query: 419 LLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGM 478 L+ + D+ G G EL++R L YS C P+D+ RG+ + +Y D + Sbjct: 317 GLVSDLGIFDQVVSTGGGGHVELLRRAAALLTYSSFCPPDDLADRGLLGVESSFYAQDAL 376 Query: 479 QIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREAL 538 ++W + R+V I+ ++Y +DESV++D ELQAW RE G L + G P SL+++E L Sbjct: 377 RLWEVISRYVEGIVSLHYKTDESVKEDFELQAWCREFTEIGLLGAQDRGFPVSLQSKEQL 436 Query: 539 VQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVN 598 +VTM IFTC+ +H++ GQ D W+PN P +M+LPPPT+K AT E +ATLP + Sbjct: 437 CHFVTMCIFTCTGQHSSNHLGQLDWYTWVPNAPCTMRLPPPTTKD-ATLETVMATLPNFH 495 Query: 599 ATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGL 658 + W L + LG + +E+F+ P+ + F+ LA + + I+ RN L Sbjct: 496 QASLQMSITWQLGRCQPTMVALGQHEEEYFSGPGPKAVLTKFREELAALDKDIEVRNAKL 555 Query: 659 VLPYTYLDPPLIENSVSI 676 LPY YL P +ENSV+I Sbjct: 556 ALPYEYLRPSRVENSVAI 573 >3D3L-A nrPDB Length = 541 Score = 649 bits (1674), Expect = 0.0, Method: Composition-based stats. Identities = 193/502 (38%), Positives = 285/502 (56%), Gaps = 7/502 (1%) Query: 176 YSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQED 235 +N +F + EM +K + W L + +IF +++ AE + WQ+D Sbjct: 12 DLGTENLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDD 71 Query: 236 AFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGIL 295 F+ QFLNG NP+L+RR LP + M L+ EL+ GSLF D +L Sbjct: 72 ELFSYQFLNGANPMLLRRSTSLPSRLVLPSGMEEL----RAQLEKELQNGSLFEADFILL 127 Query: 296 SGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP--IFLPTDDKWDW 353 GI NVI G+ Q+ AAP+ +L P G L P+ IQ+ + +FLP+D W Sbjct: 128 DGIPANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAW 186 Query: 354 LLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHIN 413 LLAK+WVRN++F HE HLL++HL+ EV +AT+R LP HP+FK LIPH RYT+ IN Sbjct: 187 LLAKSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEIN 246 Query: 414 TLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYY 473 T AR LI G + D++ G G +L++R QL Y LC P+D+ RG+ +PG Y Sbjct: 247 TRARTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALY 306 Query: 474 RDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLE 533 D +++W + R+V I+ ++Y D+ V+ D ELQAW REI G + G P S + Sbjct: 307 AHDALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQ 366 Query: 534 TREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIAT 593 ++ L ++TM +FTC+A+HAA++ GQ D AW+PN P +M++PPPT+K T + + Sbjct: 367 SQSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGS 426 Query: 594 LPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQE 653 LP V C + W LS+ D PLG + +++F+ P+ + F++ L ++ + I Sbjct: 427 LPDVRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITA 486 Query: 654 RNQGLVLPYTYLDPPLIENSVS 675 RN+ L PY YL P IENSV+ Sbjct: 487 RNEQLDWPYEYLKPSCIENSVT 508 >1RRL-A nrPDB Length = 857 Score = 553 bits (1425), Expect = e-158, Method: Composition-based stats. Identities = 156/539 (28%), Positives = 251/539 (46%), Gaps = 63/539 (11%) Query: 196 KIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCH 255 KI L K ++R+ + ++ F + + W D FA + L G+NP LIR Sbjct: 324 KISPLPVLKEIFRT--DGEQALKFPPPKVIQVSKSAWMTDEEFAREMLAGVNPNLIRCLK 381 Query: 256 YLPKNFPVTDAMVASVLG-----------PGTSLQAELEKGSLFLVDHGILSGIQTNVIN 304 P + + G ++ ++ LFL+DH IN Sbjct: 382 DFPPRSKLDSQVYGDHTSQITKEHLEPNLEGLTVDEAIQNKRLFLLDHHDPIMPYLRRIN 441 Query: 305 GKPQFSAAPMTLLYQSPGCGPLLPLAIQLS------QTPGPNSPIFLPTDDKWD---WLL 355 + A T+L+ G L PLAI+LS G S +FLP D+ + WLL Sbjct: 442 ATSTKAYATRTILFLK-NDGTLRPLAIELSLPHPQGDQSGAFSQVFLPADEGVESSIWLL 500 Query: 356 AKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTL 415 AK +V + +H+ ++H L++H + E F +AT R L HP++KLL PH R T++IN L Sbjct: 501 AKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVVHPIYKLLHPHYRDTMNINGL 560 Query: 416 ARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRG--VED------ 467 AR L+ G V++++ G E+ K ++ LP D+ RG +ED Sbjct: 561 ARLSLVNDGGVIEQTFLWGRY-SVEMSAVVYKDWVFTDQALPADLIKRGMAIEDPSCPHG 619 Query: 468 ----IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQ 523 I Y Y DG++IW A++ +V E + +YY SD+++++D ELQA +E+ G ++ Sbjct: 620 IRLVIEDYPYTVDGLEIWDAIKTWVHEYVFLYYKSDDTLREDPELQACWKELVEVGHGDK 679 Query: 524 ESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKG 583 ++ ++TRE LV+ ++I+T SA HAAV+ GQ+ + N P + P KG Sbjct: 680 KNEPWWPKMQTREELVEACAIIIWTASALHAAVNFGQYPYGGLILNRPTLSRRFMP-EKG 738 Query: 584 LATCEG--------FIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEE-APR 634 A E ++ T+ P T + + +LS+ D+ LG + ++T + Sbjct: 739 SAEYEELRKNPQKAYLKTITPKFQTLIDLSVIEILSRHASDEVYLGERDNPNWTSDTRAL 798 Query: 635 RSIATFQSRLAQISRGIQERNQG---------LVLPYTYLDPPL--------IENSVSI 676 + F ++LAQI + ERN + +PYT L P I NS+SI Sbjct: 799 EAFKRFGNKLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLPSSKEGLTFRGIPNSISI 857 >5MEF-A nrPDB Length = 569 Score = 553 bits (1424), Expect = e-157, Method: Composition-based stats. Identities = 182/578 (31%), Positives = 281/578 (48%), Gaps = 47/578 (8%) Query: 129 DHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLEL-NIKYSTAKNANFYLQ 187 D P Q+QR + ++E YQ+ L KT+ E+ ++KY ++ Sbjct: 9 DDTPDQQEQRNRAIAQQREAYQYSE----TAGILLIKTLPQSEMFSLKYLIERDKGLVSL 64 Query: 188 AGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLN 247 + A I+ + D + L + + +F P + F + D FA Q + G N Sbjct: 65 IANTLAS-NIENIFDP---FDKLEDFEEMFPLLPKPLVMNTFRN---DRVFARQRIAGPN 117 Query: 248 PVLIRRC-HYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI-------- 298 P++I R LP NFPVTDAM ++ +L + +G LF+ ++ L+ + Sbjct: 118 PMVIERVVDKLPDNFPVTDAMFQKIMFTKKTLAEAIAQGKLFITNYKGLAELSPGRYEYQ 177 Query: 299 QTNVINGKPQFSAAPMTLLYQSPG-----CGPLLPLAIQLSQTPGP-NSPIFLPTDDKWD 352 + + K + AAP+ L P G L P+AIQ++Q P P +PI+ P D K Sbjct: 178 KNGTLVQKTKTIAAPLVLYAWKPEGFGDYRGSLAPIAIQINQQPDPITNPIYTPRDGKH- 236 Query: 353 WLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHI 412 W +AK + + A+ + HEA++HL +HL+ E F LAT +L HPL LL PH ++TL I Sbjct: 237 WFIAKIFAQMADGNCHEAISHLARTHLILEPFVLATANELAPNHPLSVLLKPHFQFTLAI 296 Query: 413 NTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQL--NYSLLCLPEDIRTRGV----- 465 N LARE I G D +E +I+ +K+ N++ LP ++ RGV Sbjct: 297 NELAREQFISAGGYADDLLAGTLEASIAVIKAAIKEYMDNFTEFALPRELARRGVGIGDV 356 Query: 466 -----EDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGF 520 +P Y YRDD M +W A+E +V + + +YY S ++ D ELQ WVR + S Sbjct: 357 DQRGENFLPDYPYRDDAMLLWNAIEVYVRDYLSLYYQSPVQIRQDTELQNWVRRLVSPE- 415 Query: 521 LNQESSGIPSS--LETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPP 578 +G+ S+ L T EALV T VIF +HAAV+ Q+D A++PN+P + P Sbjct: 416 -GGRVTGLVSNGELNTIEALVAIATQVIFVSGPQHAAVNYPQYDYMAFIPNMPLATYATP 474 Query: 579 PTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIA 638 P + + + LPP + + L ++ LG YPD F + ++ + Sbjct: 475 PNKESNISEATILNILPPQKLAARQLELMRTLCVFYPNR--LG-YPDTEFVDVRAQQVLH 531 Query: 639 TFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI 676 FQ RL +I + I N+ + PYTYL P + NS SI Sbjct: 532 QFQERLQEIEQRIVLCNEKRLEPYTYLLPSNVPNSTSI 569 >4WFO-A nrPDB Length = 858 Score = 538 bits (1386), Expect = e-153, Method: Composition-based stats. Identities = 144/562 (25%), Positives = 242/562 (43%), Gaps = 68/562 (12%) Query: 173 NIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHW 232 ++ S + + K L+R+ + + I F + + + W Sbjct: 307 DVHDLYEGGIKLPRDVISTIIPLPV-----IKELYRT--DGQHILKFPQPHVVQVSQSAW 359 Query: 233 QEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVAS---------VLGPGTSLQAELE 283 D FA + + G+NP +IR P + A+ + G ++ L Sbjct: 360 MTDEEFAREMIAGVNPCVIRGLEEFPPKSNLDPAIYGDQSSKITADSLDLDGYTMDEALG 419 Query: 284 KGSLFLVDHGILSGIQTNVING-KPQFSAAPMTLLYQSPGCGPLLPLAIQLSQT------ 336 LF++D+ + IN + A T+L+ G L P+AI+LS Sbjct: 420 SRRLFMLDYHDIFMPYVRQINQLNSAKTYATRTILFL-REDGTLKPVAIELSLPHSAGDL 478 Query: 337 PGPNSPIFLPTDDKWD---WLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLP 393 S + LP + + WLLAK +V + +H+ ++H L++H E F +AT R L Sbjct: 479 SAAVSQVVLPAKEGVESTIWLLAKAYVIVNDSCYHQLMSHWLNTHAAMEPFVIATHRHLS 538 Query: 394 HCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSL 453 HP++KLL PH R ++IN LAR+ LI +++ + + + E+ K ++ Sbjct: 539 VLHPIYKLLTPHYRNNMNINALARQSLINANGIIETTF-LPSKYSVEMSSAVYKNWVFTD 597 Query: 454 LCLPEDIRTRGV--ED----------IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDES 501 LP D+ RGV +D I Y Y DG++IW A++ +V E + +YY D+ Sbjct: 598 QALPADLIKRGVAIKDPSTPHGVRLLIEDYPYAADGLEIWAAIKTWVQEYVPLYYARDDD 657 Query: 502 VQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQF 561 V++D ELQ W +E KG + + L+T E LV+ ++I+ SA HAAV+ GQ+ Sbjct: 658 VKNDSELQHWWKEAVEKGHGDLKDKPWWPKLQTLEDLVEVCLIIIWIASALHAAVNFGQY 717 Query: 562 DSCAWMPNLPPSMQLPPPTSKGLATCEG--------FIATLPPVNATCDVILALWLLSKE 613 + N P + + P KG E ++ T+ T + + +LS Sbjct: 718 PYGGLIMNRPTASRRLLP-EKGTPEYEEMINNHEKAYLRTITSKLPTLISLSVIEILSTH 776 Query: 614 PGDQRPLGTYPDEHFTEE-APRRSIATFQSRLAQISRGIQERNQG----------LVLPY 662 D+ LG + H+T + ++ F ++L +I + RN + LPY Sbjct: 777 ASDEVYLGQRDNPHWTSDSKALQAFQKFGNKLKEIEEKLVRRNNDPSLQGNRLGPVQLPY 836 Query: 663 TYLDPPL--------IENSVSI 676 T L P I NS+SI Sbjct: 837 TLLYPSSEEGLTFRGIPNSISI 858 >2IUJ-A nrPDB Length = 853 Score = 531 bits (1368), Expect = e-151, Method: Composition-based stats. Identities = 169/753 (22%), Positives = 297/753 (39%), Gaps = 156/753 (20%) Query: 73 PPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAG----TLVLQEGTAKVSWA 128 P + + + + P G + F C W+ + + + Sbjct: 108 PGAFYIKNYMQNEFYLKSLILEDIPNHGTIHFICNSWVYNSKHYKTDRIFFANNTYLPSE 167 Query: 129 DHHPVLQQQRQEELQ--------ARQE---MYQWKAYN-------------PGWPHCLD- 163 P++ + R+EEL+ R+E +Y + YN P Sbjct: 168 TPAPLV-KYREEELKNVRGDGTGERKEWDRIYDYDVYNDLGDPDKGEKYARPVLGGSALP 226 Query: 164 ---------EKTVED-----------LELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDR 203 KT +D L + + K+++F + A+ + L D Sbjct: 227 YPRRGRTGRGKTRKDPNSEKPGDFVYLPRDEAFGHLKSSDFLAYGIKSVAQDVLPVLTDA 286 Query: 204 KGL------WRSLNEMKRIF--------------------------------NFRRTPAA 225 + + E+++++ + Sbjct: 287 FDGNLLSLDFDNFAEVRKLYEGGVTLPTNFLSNITPIPIIKELFRTDGEQFLKYPPPKVM 346 Query: 226 EHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGP----------- 274 + W D FA + + GLNP +I+ + + FP++ + G Sbjct: 347 QVDKSAWMTDEEFARETIAGLNPNVIK----IIEEFPLSSKLDTQAYGDHTCIITKEHLE 402 Query: 275 ----GTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLA 330 G +++ ++ LF++DH IN + A T+ + G L PLA Sbjct: 403 PNLGGLTVEQAIQNKKLFILDHHDYLIPYLRKINANTTKTYATRTIFFLK-NDGTLTPLA 461 Query: 331 IQLS------QTPGPNSPIFLPTDDKWD---WLLAKTWVRNAEFSFHEALTHLLHSHLLP 381 I+LS + GP S +++P+ + + WLLAK +V + +H+ ++H L++H + Sbjct: 462 IELSKPHPQGEEYGPVSEVYVPSSEGVEAYIWLLAKAYVVVNDACYHQIISHWLNTHAVV 521 Query: 382 EVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSEL 441 E F +AT R L HP++KLL PH R T++IN+LAR+ L+ +++++ G E+ Sbjct: 522 EPFVIATNRHLSVVHPIYKLLFPHYRDTMNINSLARKSLVNADGIIEKTFLWGRY-SLEM 580 Query: 442 IQRNMKQLNYSLLCLPEDIRTRGV--ED----------IPGYYYRDDGMQIWGAVERFVS 489 K ++ LP D+ RGV +D I Y Y DG++IW A++ +V Sbjct: 581 SAVIYKDWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVE 640 Query: 490 EIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTC 549 E + YY SDE +Q D ELQAW +E+ G + + ++TRE LV+ +I+ Sbjct: 641 EYVSFYYKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASATLIWIA 700 Query: 550 SAKHAAVSAGQFDSCAWMPNLPPSMQL-------PPPTSKGLATCEGFIATLPPVNATCD 602 SA HAAV+ GQ+ + N P + P + + F+ T+ T Sbjct: 701 SALHAAVNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLI 760 Query: 603 VILALWLLSKEPGDQRPLGTYP-DEHFTEEA-PRRSIATFQSRLAQISRGIQERNQGLVL 660 + + +LS+ D+ LG +++T +A P + F L +I + + E+N L Sbjct: 761 DLTIIEILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKNLEEIEKKLIEKNNDETL 820 Query: 661 ---------PYTYLDPPL--------IENSVSI 676 PYT L P I NS+SI Sbjct: 821 RNRYGPAKMPYTLLYPSSEEGLTFRGIPNSISI 853 >2IUK-A nrPDB Length = 864 Score = 525 bits (1352), Expect = e-149, Method: Composition-based stats. Identities = 151/538 (28%), Positives = 243/538 (45%), Gaps = 62/538 (11%) Query: 197 IKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHY 256 I L K ++R+ + + + F A+ + D FA + + G+NP +IRR Sbjct: 331 ISPLPALKEIFRT--DGENVLQFPPPHVAKVSKSGVMTDEEFAREVIAGVNPNVIRRLQE 388 Query: 257 LPKNFPVTDAMVASVLGP-----------GTSLQAELEKGSLFLVDHGILSGIQTNVING 305 P + + G +++ L LF++D+ IN Sbjct: 389 FPPKSTLDPTLYGDQTSTITKEQLEINMGGVTVEEALSTQRLFILDYQDAFIPYLTRINS 448 Query: 306 KPQ-FSAAPMTLLYQSPGCGPLLPLAIQLSQT------PGPNSPIFLPTDDKWD---WLL 355 P + A T+L+ G L PLAI+LS+ GP S + LP + D WLL Sbjct: 449 LPTAKAYATRTILFLK-DDGTLKPLAIELSKPHPDGDNLGPESIVVLPATEGVDSTIWLL 507 Query: 356 AKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTL 415 AK V + +H+ ++H L++H + E F +AT R L HP++KLL PH R T++IN L Sbjct: 508 AKAHVIVNDSGYHQLVSHWLNTHAVMEPFAIATNRHLSVLHPIYKLLYPHYRDTININGL 567 Query: 416 ARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGV--ED------ 467 AR+ LI ++++S + + E+ K ++ LP D+ RG+ ED Sbjct: 568 ARQSLINADGIIEKSF-LPGKYSIEMSSSVYKNWVFTHQALPADLVKRGLAIEDPSAPHG 626 Query: 468 ----IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQ 523 I Y Y DG++IW A++ +V E + +YYP+D +VQ D ELQAW +E KG + Sbjct: 627 LRLVIEDYPYAVDGLEIWDAIKTWVHEYVSLYYPTDAAVQQDTELQAWWKEAVEKGHGDL 686 Query: 524 ESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLP-------PSMQL 576 + +T E L+Q +++++T SA HAAV+ GQ+ + N P P+ Sbjct: 687 KEKPWWPKKQTTEDLIQSCSIIVWTASALHAAVNFGQYPYGGLILNRPTLARRFIPAEGT 746 Query: 577 PPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHF-TEEAPRR 635 P + ++ T+ P T + + +LS+ D+ LG ++ T++ Sbjct: 747 PEYDEMVKNPQKAYLRTITPKFETLIDLSVIEILSRHASDEIYLGERETPNWTTDKKALE 806 Query: 636 SIATFQSRLAQISRGIQERNQG---------LVLPYTYLDPPL--------IENSVSI 676 + F S+L I I RN + LPYT L I NS+SI Sbjct: 807 AFKRFGSKLTGIEGKINARNSDPSLRNRTGPVQLPYTLLHRSSEEGLTFKGIPNSISI 864 >4G32-A nrPDB Length = 688 Score = 502 bits (1292), Expect = e-142, Method: Composition-based stats. Identities = 160/498 (32%), Positives = 231/498 (46%), Gaps = 28/498 (5%) Query: 198 KGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYL 257 L+ + G LN + +F R P +F ++D FA + G NP+LIRR L Sbjct: 200 SNLVTQGGQGDGLNRFRAVFGTLRLPEVADSF---RDDEAFAYWRVAGPNPLLIRRVDAL 256 Query: 258 PKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGIL-----SGIQTNVINGKPQFSAA 312 P NFP+ + V+G SL L+L+D+ L SG ++ G F+ A Sbjct: 257 PANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTG-TGFAYA 315 Query: 313 PMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLP----TDDKWDWLLAKTWVRNAEFSFH 368 P+ L LLP+AIQ Q P + P +D W W +AKT V+ AE ++H Sbjct: 316 PIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYH 375 Query: 369 EALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVD 428 E HL +HL+ E F LAT R L HPL LL PH TL IN A +L+ +D Sbjct: 376 EMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFID 435 Query: 429 RSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVED---IPGYYYRDDGMQIWGAVE 485 I+ N ++ LPE ++ R V+D +P Y YRDDG+ +W A+ Sbjct: 436 VMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIR 495 Query: 486 RFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMV 545 ++ ++ + +YY SD V D EL AWV E+ G + +G + R LV+ +TMV Sbjct: 496 QWAADYVAVYYASDGDVTADVELAAWVGEVIGSG----KVAGF-RPITGRSQLVEVLTMV 550 Query: 546 IFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVIL 605 IFT SA+HAAV+ Q + P + P P S + ++ +PP + + Sbjct: 551 IFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVN 610 Query: 606 ALWLLSK----EPGDQRPLGTYPDEHFTEE---APRRSIATFQSRLAQISRGIQERNQGL 658 LL GD R G F++ A + FQ+RL ++ I+ RNQ Sbjct: 611 IYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQAR 670 Query: 659 VLPYTYLDPPLIENSVSI 676 PY YL P I S +I Sbjct: 671 RKPYEYLLPSRIPASTNI 688 >5FNO-A nrPDB Length = 605 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 139/575 (24%), Positives = 235/575 (40%), Gaps = 57/575 (9%) Query: 138 RQEELQARQEMYQWK-------AYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGS 190 R E++ +Q + +Y PG P D ++ D + +Q+ Sbjct: 52 RTAEIRLKQATLLYGPSLLGNASYFPGGPLG-DAISLRDQTVWE-------GAAVVQSLR 103 Query: 191 AFAEM-KIKGLLDRKGLWRSLNEMKRIFNFRRTPAAE-----HAFEHWQEDAFFASQFLN 244 AF + K+ + + G SL++ K ++ + E++ D F+ + L+ Sbjct: 104 AFTDAAKVAANIKQNGGLNSLDDFKVLYQDGWKGSVPQGIARGQSENYTSDLLFSMERLS 163 Query: 245 GLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVIN 304 +NP +++R H P TSL+A G LF+ DH Q N Sbjct: 164 -VNPYILKRLHPTEDALPFQVDRATVKQLTKTSLKALHAAGRLFVADHSY----QRNYTR 218 Query: 305 GKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTD-DKWDWLLAKTWVRNA 363 ++SAA L Y P LPLAI+ T + P D D +WLLAK N Sbjct: 219 LANRYSAACTALFYLDPRSNQFLPLAIK---TNVGADLTYTPLDTDNNNWLLAKIMFNNN 275 Query: 364 EFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVP 423 + FH + H+ + H + E+ LA LR + HP+ L+ + L +L Sbjct: 276 DL-FHGQIFHVAYPHAIAEIVHLAALRTMSARHPVLALMERLMYQAYAVRPLGERVLFNK 334 Query: 424 GQVVDRSTGIGIEGFSELIQRNMKQLN-YSLLCLPEDIRTRGVED------IPGYYYRDD 476 G + +++ + + + + + L D+R RG+ D +P + + +D Sbjct: 335 GGLFEQNFAYPQDMVYKFVGDSYPTTGRWRAGYLDTDVRARGLVDADYGPELPHFPFYED 394 Query: 477 GMQIWGAVERFVSEIIG-IYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETR 535 G ++ + RFV + Y+ SDE V D ELQAWV E + P L+TR Sbjct: 395 GSRLVEVIRRFVRSFVDATYHESDEMVAKDAELQAWVAEANGPAGVEDFE---PGPLDTR 451 Query: 536 EALVQYVTMVIFTCSAKHAAVSAGQ-FDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 594 E LV+ +T + + H ++ G+ + +P P ++ P PTSK T + L Sbjct: 452 ERLVEVLTHMAWLTGCAHHVLNQGEPVTASGVLPMHPTALYAPVPTSKANTT-ADLLGYL 510 Query: 595 PPVNATCDVILALWLLSKE---PGDQ--RPLGTYPDEHFT-EEAPRRSIATFQSRLAQIS 648 P + D + L ++ P +Q R + P EA RR+ F + +IS Sbjct: 511 PSAQKSVDQVTLLARFNRPDVVPTNQTLRYMFAAPQLLLGNGEAYRRANQRFVRAMGRIS 570 Query: 649 RGIQER-------NQGLVLPYTYLDPPLIENSVSI 676 ++ R +QG+ + LDP I +S+ Sbjct: 571 DEVKARRFDDRGLSQGMPFIWQALDPGNIPFYLSV 605 >5FX8-A nrPDB Length = 618 Score = 450 bits (1158), Expect = e-127, Method: Composition-based stats. Identities = 132/596 (22%), Positives = 232/596 (38%), Gaps = 68/596 (11%) Query: 124 KVSWADHHPVLQQQRQEELQARQEMYQWK--------AYNPGWPHCLDEKTVEDLELNIK 175 + D + Q R + ++E++ + Y G + D+ L + Sbjct: 48 TLPNNDPN---QGARNASIARKRELFLYGPSTLGQTTFYPTGELGN--NISARDVLLWRQ 102 Query: 176 YSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAE-----HAFE 230 + + A Y +A FA++ +G +++L++ ++N + Sbjct: 103 DAANQTATAYREANETFADI------TSRGGFKTLDDFALLYNGHWKESVPEGISKGMLS 156 Query: 231 HWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLV 290 + D F+ + L+ NP +++R H P + T+L+A + G LFLV Sbjct: 157 NCTSDLLFSMERLSS-NPYVLKRLHPTKDKLPFSVESKVVKKLTATTLEALHKGGRLFLV 215 Query: 291 DHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDK 350 DH Q +++AA L Y LPLAI+ T + P DDK Sbjct: 216 DHSY----QKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIK---TNVGVDLTYTPLDDK 268 Query: 351 WDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTL 410 DWLLAK N + + + H+L H +PE+ A R L HP+ +L Sbjct: 269 DDWLLAKIMFNNNDLFYSQM-YHVLF-HTIPEIVHEAAFRTLSDRHPVMGVLNRLMYQAY 326 Query: 411 HINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNM--KQLNYSLLCLPEDIRTRGVED- 467 I + +L PG D++ G+ + + L +D+R+RG+ Sbjct: 327 AIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGYLEKDLRSRGLIGE 386 Query: 468 -----IPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDE----SVQDDRELQAWVREIFSK 518 +P + + +D ++ GA+ RF+ + Y +D+ ++ D ELQ W+ E Sbjct: 387 DSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGALLRDYELQNWIAEANGP 446 Query: 519 GFLNQESSGIP-SSLETREALVQYVTMVIFTCSAKHAAVSAGQ-FDSCAWMPNLPPSMQL 576 + P + L R LV +T V + H ++ G +P P ++ Sbjct: 447 A----QVRDFPAAPLRRRAQLVDVLTHVAWITGGAHHVMNQGSPVKFSGVLPLHPAALYA 502 Query: 577 PPPTSK---GLATCEGFIATLPPVNATCDVILALWLLSK-EPGDQ----RPLGTYPDEHF 628 P PT+K G T G +A LP + + L ++ + GD+ R PD Sbjct: 503 PIPTAKGATGNGTRAGLLAWLPNERQAVEQVSLLARFNRAQVGDRKQTVRDAFAAPDLLA 562 Query: 629 T-EEAPRRSIATFQSRLAQISRGIQER-------NQGLVLPYTYLDPPLIENSVSI 676 + A F +ISR I R +QG+ +T L+P + +S+ Sbjct: 563 GNGPGYAAANARFVEDTGRISREIAGRGFDGKGLSQGMPFVWTALNPAVNPFFLSV 618 >6NS2-A nrPDB Length = 769 Score = 374 bits (961), Expect = e-104, Method: Composition-based stats. Identities = 137/568 (24%), Positives = 229/568 (40%), Gaps = 105/568 (18%) Query: 139 QEELQARQEMYQWKAYNPGWP--HCLDEKTVEDLELNI--------------KYSTAKNA 182 + EL ++ +YQW G+P +D +L + + + Sbjct: 132 KRELDLKKRIYQWSDGTDGYPPHLKVDGNDEANLPADERQSKPGSARSEGVGQIFDMQET 191 Query: 183 NFYLQAGSAFAEMKIKGLLDRKGLWR--SLNEMKRIFNFRRTPAAEH------------- 227 F + A + + K + ++ +L ++++ FN + P + Sbjct: 192 AFVSKIAQAVSFIIPKDIDHENTPYKGPTLADVEK-FNKAQFPKTDGDASNQDNLNKAAD 250 Query: 228 --------AFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQ 279 ++ W DA FA Q +G+NP I +++A + ++ Sbjct: 251 IMKGRNIGEYDDWYSDARFAQQHFSGVNPSTIETASQDKIKEYISEAQKQGL----DKVK 306 Query: 280 AELEKGSLFLV-DHGIL---SGIQTNVINGKPQFS--------------AAPMTLLYQSP 321 A LE G L+ D+ +G I + AA +++Q Sbjct: 307 AILEDGKDILIQDYSYFREATGATNEQIFQNTVYELKGTTPTGKTTSRYAAASVVIFQLH 366 Query: 322 GCGPLLPLAIQLSQTPGPNSPIFL------PTD-------DKWDWLLAKTWVRNAEFSFH 368 G L PLAI L ++ I + P D + W W AKT + A+++ H Sbjct: 367 EDGRLHPLAITLDYKGSLDNSITIFNRRLSPDDTCDIAEKEDWPWRYAKTVAQTADWARH 426 Query: 369 EALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVD 428 E THL+ +H++ E +AT R +P L+++L PH TL +N AR+LL+ V+ Sbjct: 427 EVATHLVDTHMIEEAIIVATNRIIPEGELLYEILSPHWFRTLSLNAAARKLLVP--GVIA 484 Query: 429 RSTGIG-------IEGFS--ELIQRNMKQLNYSLLCLPEDIRTRGVEDIPG--------Y 471 R G G +G + +LI + K N+ +P D++ RG DI G Y Sbjct: 485 RIAGFGPTSPSLDFKGNNAFKLIDWSYKNFNFQDKYIPNDLKKRGF-DIKGDKSGKYKNY 543 Query: 472 YYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSS 531 Y +D +WG + FV +I Y SD VQ D + W +EI + G + + Sbjct: 544 PYANDMYLLWGIIRNFVKTVIESQYTSDHVVQKDPYIGGWCKEIQTNGQI-----PTFPT 598 Query: 532 LETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLA---TCE 588 + T E L+ VTM I T S +H AV+ Q +++P PP++ P P T + Sbjct: 599 ITTVEQLIDAVTMCIHTASPQHTAVNYLQDYYYSFVPAKPPALCTPLPQDLSALQGYTEK 658 Query: 589 GFIATLPPVNATCDVILALWLLSKEPGD 616 A LP T D+ WLL+ + + Sbjct: 659 DLTAALPI--GTEDMKWKDWLLAAQLPE 684 >5EK8-A nrPDB Length = 668 Score = 176 bits (446), Expect = 3e-44, Method: Composition-based stats. Identities = 81/493 (16%), Positives = 158/493 (32%), Gaps = 95/493 (19%) Query: 164 EKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNF-RRT 222 E+T +D + K+ +AN A+ I L+ K SL +++ + Sbjct: 180 EETPDDYSVGRKFQAYASANVLTPIK---AKHTIANTLNPKEP--SLTQIQADYPPNLTI 234 Query: 223 PAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVT---DAMVASVLGPGTSLQ 279 + + D +F + LNG+NP L++R P F ++ D +++ Sbjct: 235 NLDREKPGYTRSDEYFVLRVLNGMNPCLLKRSKSDPNQFKMSFIWDNYEKDTEHDLHNVE 294 Query: 280 AE--LEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTP 337 A L+ G LF P + QS L P +P Sbjct: 295 AYFVLKDGKLF------------------------PTMITIQSRYPDSLAP------HSP 324 Query: 338 GPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHP 397 + ++ P D + WL AK R A EA+ H +H+ E + +A R L +P Sbjct: 325 LKDREVYTPNDGE-KWLQAKRIFRTAALFDGEAIEHYAKAHVQMEQYAVACFRNL-RKNP 382 Query: 398 LFKLLIPHTRYTLHINTLARELLIVPG-QVVDRSTGIGIEGFSELIQRNMKQLNYSLLCL 456 + +L PH + ++IN +LL+ P + + + GF ++ + ++ Sbjct: 383 IRLMLTPHLKSIININRRGDDLLVEPNLGLFVTNGPLTYPGFLQMCTEVVATYDWKDWQP 442 Query: 457 PEDIRTRGVEDIPGYYYRDDGMQIWGA----------------------VERFVSEII-- 492 + I + Y W + RF +++ Sbjct: 443 RQPICD-------DHKYAKAANLYWQILTEYVDAFFAKHQQAIADEWVEIRRFSEDLVEH 495 Query: 493 GIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGI--------------PSSLETREAL 538 + Y E + + + + + + S + L Sbjct: 496 SMPYQPIEGIMANTDSDYEWYDTGELDKPDLPRATFNGKTKVIRPITNSNQPSATDIDNL 555 Query: 539 VQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVN 598 Q +IF + H V+ Q D + +++ S+ P Sbjct: 556 KQCCRHIIFHTTLWHTWVNDSQSDEGGELAYNSLALRNGSFGSETDPNIA------PDPI 609 Query: 599 ATCDVILALWLLS 611 + + +L+ Sbjct: 610 EATNQVYIFSVLN 622 >1KHO-A nrPDB Length = 370 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Query: 8 VSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTL---PEDVGRV 64 ++TG AGT D + I G++ +DN G +F G+++ + L + + Sbjct: 262 ITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPGNDFMTGSQDTYTFKLKDKNLKIDDI 321 Query: 65 LLLRVHKAP 73 + + K+ Sbjct: 322 QNMWIRKSK 330 >2WXU-A nrPDB Length = 370 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 43/111 (38%), Gaps = 9/111 (8%) Query: 8 VSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED---VGRV 64 +ST AGT D + I G++ +DN G +F G+++ + L ++ + + Sbjct: 262 ISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDI 321 Query: 65 LLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGT 115 + + K PDA+ ++ + +W+ G T Sbjct: 322 QNMWIRKRKYTAF------PDAYKPENIKIIANGKVVVDKDINEWISGNST 366 >1OLP-A nrPDB Length = 370 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 40/113 (35%), Gaps = 3/113 (2%) Query: 6 VRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVL 65 V + T + AGT + + I G LDN G +FT E + + L + Sbjct: 260 VMIKTADVQDAGTDNYIYFGIETKDGVKEEWALDNPGNDFTRNQEGTYTLKLKNKNTKYS 319 Query: 66 LLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVL 118 + K + +A D W + ++ L +W+ G T L Sbjct: 320 DI---KNMWIRDEKLTVATDGWKPSYVKVIAGDKVRLEKNINEWISGGTTYTL 369 >5ZCR-A nrPDB Length = 728 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 23/151 (15%), Positives = 45/151 (29%), Gaps = 13/151 (8%) Query: 149 YQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGS----AFAEMKIKGLLDRK 204 YQ + G+P+ V DL + I GL + K Sbjct: 191 YQLTYWKKGYPNYRRFFAVNDLIAVRIELDEVFRESHEIIAKLPVDGLRIDHIDGLYNPK 250 Query: 205 GLWRSLNEM----KRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKN 260 L ++ K I+ + E + W+ D FLN +N +L+ Sbjct: 251 EYLDKLRQLVGNDKIIYVEKILSINEKLRDDWKVDGTTGYDFLNYVNMLLVDGSGEEEL- 309 Query: 261 FPVTDAMVASVLGPGTSLQAELEKGSLFLVD 291 + +G ++ + + + + Sbjct: 310 ----TKFYENFIGRKINIDELIIQSKKLVAN 336 >5M1Z-A nrPDB Length = 367 Score = 33.2 bits (74), Expect = 0.37, Method: Composition-based stats. Identities = 23/172 (13%), Positives = 50/172 (29%), Gaps = 14/172 (8%) Query: 119 QEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYS- 177 +GT S + L + E +R + Y W+ + + + Sbjct: 101 PKGTVLCSGSSIPSDLSETLIEVYASRDKGYTWEFVSHVALGGEALPNPGLTPVWEPFLM 160 Query: 178 --TAKNANFYLQA--GSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQ 233 K +Y + ++ + W + + + N+ P + Sbjct: 161 TYKEKLILYYSDQRDNATHSQKLVHQTTTDLKKWSKVVDDTKYANYYARPGMPTVAKLPN 220 Query: 234 EDAFFASQFLNGLNP--------VLIRRCHYLPKNFPVTDAMVASVLGPGTS 277 + + ++ G NP + R P+ F + A V GT+ Sbjct: 221 NEYIYVYEYGGGPNPPAGSDYWFPVYYRLSKDPQKF-LNKAHHQIVSNDGTT 271 >5A01-A nrPDB Length = 710 Score = 32.0 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 43/120 (35%), Gaps = 9/120 (7%) Query: 289 LVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTD 348 L D T I P F+ A L G + P AIQ +T P F D Sbjct: 88 LQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNI-PEAIQSYRTALKLKPDF--PD 144 Query: 349 DKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRY 408 + LA +++ ++ L S ++ E L R LP HP +L P T Sbjct: 145 AYCN--LAHCLQIVCDWTDYDIRMKKLVS-IVTEQ--LEKNR-LPSVHPHHSMLYPLTHD 198 >4R1D-A nrPDB Length = 569 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 57/164 (34%), Gaps = 19/164 (11%) Query: 386 LATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLI--VPGQVV--DRSTGIGIEGFSEL 441 +A +RQ PL + IP T ++ A + + P + D L Sbjct: 40 VALIRQTA---PLPVIFIPGIMGT-NLRNKADKSEVWRPPNGLWPMDDLFA----SIGAL 91 Query: 442 IQRNMKQLNYSLLCLPED---IRTRGVEDIPGYYYRDDGMQI--WG-AVERFVSEIIGIY 495 + L + + +G D+ ++ ++ WG + + ++G+ Sbjct: 92 WTWAWRGPKARQELLKAEQVEVDDQGTIDVGQSGLSEEAARLRGWGKVMRSAYNPVMGLM 151 Query: 496 YPSDESVQDDRELQAWVR-EIFSKGFLNQESSGIPSSLETREAL 538 +++ RELQAW E S E G ++ E L Sbjct: 152 ERRLDNIVSRRELQAWWNDEALSPPGDQGEEQGKVGPIDEEELL 195 >5WYK-BB nrPDB Length = 943 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 24/68 (35%), Gaps = 1/68 (1%) Query: 21 KVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLG 80 V ++ G + L D G +G+++ + + + VG V L ++ + Sbjct: 112 TVLLNFNGHKAAITLLQFDGTGTRLISGSKDS-NIIVWDLVGEVGLYKLRSHKDSITGFW 170 Query: 81 PLAPDAWF 88 D Sbjct: 171 CQGEDWLI 178 >4GRX-A nrPDB Length = 465 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 23/69 (33%) Query: 381 PEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSE 440 E ++L +P H +++ H ++ R L + + G +G E Sbjct: 23 AETYSLYGFTDMPSVHQRGTVVVTHGEGPYIVDVHGRRYLDANSGLWNMVAGFDHKGLIE 82 Query: 441 LIQRNMKQL 449 + + Sbjct: 83 AAKAQYDRF 91 >2DEP-A nrPDB Length = 356 Score = 29.7 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 33/96 (34%), Gaps = 1/96 (1%) Query: 117 VLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKY 176 LQ WAD ++Q ++ ++ R W P W LD++ +E Sbjct: 52 SLQPTEGNFQWADADRIVQFAKENGMELRFHTLVWHNQTPDW-FFLDKEGKPMVEETDPQ 110 Query: 177 STAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNE 212 +N LQ + + D W +NE Sbjct: 111 KREENRKLLLQRLENYIRAVVLRYKDDIKSWDVVNE 146 >4FGZ-A nrPDB Length = 266 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 100 GHLLFPCYQWLEGAGTLVLQE--GTAKVSWADHHPVLQQQRQEEL 142 L CY+WL+ GTL++ + T K +W D +QR+ L Sbjct: 139 NKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTL 183 >6BHR-G nrPDB Length = 95 Score = 29.3 bits (64), Expect = 5.4, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 25/67 (37%) Query: 489 SEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFT 548 + + +Y + + Q +E++ W+ E N + I +L L + +T Sbjct: 17 RDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGV 76 Query: 549 CSAKHAA 555 H A Sbjct: 77 GGPGHKA 83 >4E3Q-A nrPDB Length = 473 Score = 29.3 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 9/69 (13%), Positives = 24/69 (34%) Query: 381 PEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSE 440 E ++L +P H +++ H ++ R L + + G +G + Sbjct: 31 AETYSLYGFTDMPSLHQRGTVVVTHGEGPYIVDVNGRRYLDANSGLWNMVAGFDHKGLID 90 Query: 441 LIQRNMKQL 449 + ++ Sbjct: 91 AAKAQYERF 99 >4MOP-A nrPDB Length = 633 Score = 28.9 bits (63), Expect = 7.1, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 15/57 (26%), Gaps = 3/57 (5%) Query: 510 AWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAW 566 W E + + +P E E V T + H + F A Sbjct: 406 DWWNEKVKNHMMQHQEDPLPIPFEDPEPQV---TTLFQPSHPWHTQIHRDAFSYGAV 459 >5TEO-A nrPDB Length = 110 Score = 28.9 bits (63), Expect = 8.2, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 25/67 (37%) Query: 489 SEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFT 548 + + +Y + + Q +E++ W+ E N + I +L L + +T Sbjct: 27 RDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGV 86 Query: 549 CSAKHAA 555 H A Sbjct: 87 GGPGHKA 93 >5O2U-A nrPDB Length = 500 Score = 28.9 bits (63), Expect = 8.2, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 25/67 (37%) Query: 489 SEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFT 548 + + +Y + + Q +E++ W+ E N + I +L L + +T Sbjct: 294 RDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGV 353 Query: 549 CSAKHAA 555 H A Sbjct: 354 GGPGHKA 360 >2OWC-A nrPDB Length = 503 Score = 28.6 bits (62), Expect = 8.8, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 34/113 (30%), Gaps = 13/113 (11%) Query: 137 QRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKY---STAKNANFYLQAGSAFA 193 + +E A +E W + + + K ++ + +A SA A Sbjct: 125 EEREAFAAFREREAW--WLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALA 182 Query: 194 EMKIKGLLDRKGLWRSLNEMK--------RIFNFRRTPAAEHAFEHWQEDAFF 238 E + +R +K RI AE + E W +F Sbjct: 183 EEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWF 235 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.128 0.345 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,172,891 Number of Sequences: 36641 Number of extensions: 989834 Number of successful extensions: 2695 Number of sequences better than 10.0: 35 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 2480 Number of HSP's gapped (non-prelim): 70 length of query: 676 length of database: 10,336,785 effective HSP length: 104 effective length of query: 572 effective length of database: 6,526,121 effective search space: 3732941212 effective search space used: 3732941212 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)