BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O14732 (288 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2CZH-A nrPDB 591 e-169 2BJI-A nrPDB 344 2e-95 4AS5-A nrPDB 341 3e-94 1IMD-A nrPDB 340 4e-94 6IB8-A nrPDB 149 1e-36 5ZHH-A nrPDB 130 6e-31 2P3V-A nrPDB 127 8e-30 2PCR-A nrPDB 123 7e-29 3LV0-A nrPDB 123 1e-28 5J16-A nrPDB 117 4e-27 1G0H-A nrPDB 93 2e-19 2Q74-A nrPDB 92 3e-19 1XI6-A nrPDB 87 1e-17 1VDW-A nrPDB 86 3e-17 3QMF-A nrPDB 78 5e-15 5YHT-A nrPDB 76 2e-14 5EQA-A nrPDB 75 3e-14 1JP4-A nrPDB 60 1e-09 1LBZ-A nrPDB 56 2e-08 4O7I-A nrPDB 55 4e-08 3B8B-A nrPDB 54 7e-08 2WEF-A nrPDB 54 8e-08 4N81-A nrPDB 49 2e-06 4QXD-A nrPDB 48 6e-06 5ESY-A nrPDB 45 4e-05 1KA0-A nrPDB 42 2e-04 5DJK-A nrPDB 32 0.30 6AAE-A nrPDB 31 0.60 3KRZ-A nrPDB 28 5.5 4MH4-A nrPDB 27 8.1 >2CZH-A nrPDB Length = 299 Score = 591 bits (1523), Expect = e-169, Method: Compositional matrix adjust. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL 60 MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL Sbjct: 12 MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL 71 Query: 61 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI 120 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI Sbjct: 72 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI 131 Query: 121 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP 180 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP Sbjct: 132 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP 191 Query: 181 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR 240 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR Sbjct: 192 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR 251 Query: 241 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK 288 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK Sbjct: 252 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK 299 >2BJI-A nrPDB Length = 277 Score = 344 bits (883), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 148/275 (53%), Positives = 213/275 (77%) Query: 13 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72 A PW+EC AV LA +AG+++R+AL E + K+S ADLVT TD VE ++I+ ++E+ Sbjct: 2 ADPWQECMDYAVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKEK 61 Query: 73 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVH FP VAVSIGF V +++EFG+ Sbjct: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFGI 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y C E+++YTGR+G+GAFCNGQ+L+VS + D++K+L++TE+G R P T+++ LSN+ER Sbjct: 122 VYSCLEDKMYTGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIER 181 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 LL HG+R +G++ L +C +A+GAADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 182 LLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTGG 241 Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 P DLM+ RV+A+S + +A IA+ +Q I RDDE Sbjct: 242 PFDLMSRRVIASSNKTLAERIAKEIQIIPLQRDDE 276 >4AS5-A nrPDB Length = 277 Score = 341 bits (874), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 146/275 (53%), Positives = 209/275 (76%) Query: 13 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72 A PW+EC AV LA +AG++IR+AL E V K+S ADLVT TD VE +++S ++E+ Sbjct: 2 ADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEK 61 Query: 73 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 +P H FI EE+ A+G K V T PTW+IDPIDGT NFVHRFP VAVSIGF V +E+EFG+ Sbjct: 62 YPCHSFIGEESVAAGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGI 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y C E+++YTGR+G+GAFCNGQ+L+VS + D++K+L++TE+G R P TL++ LSNME+ Sbjct: 122 VYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEK 181 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 L HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 182 LCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGG 241 Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 P DLM+ R++AA++ +A IA+ ++ I RDDE Sbjct: 242 PFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDE 276 >1IMD-A nrPDB Length = 277 Score = 340 bits (873), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 147/275 (53%), Positives = 209/275 (76%) Query: 13 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72 A PW+EC AV LA +AG+++ +A+ E V K+S DLVT TD VE ++IS ++E+ Sbjct: 2 ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61 Query: 73 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV Sbjct: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y C E ++YT R+G+GAFCNGQ+L+VS + D++K+L++TE+G R P T+++ LSNME+ Sbjct: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 L HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 P DLM+ RV+AA+ R +A IA+ +Q I RDDE Sbjct: 242 PFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 >6IB8-A nrPDB Length = 271 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 87/254 (34%), Positives = 134/254 (52%), Gaps = 6/254 (2%) Query: 23 AVQLALRAGQIIRKAL-TEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAE 81 AV+ A +AG +I K T + +++ + D VT D E +II +R+ +P H I E Sbjct: 12 AVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITE 71 Query: 82 EAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERL 141 E SG W+IDP+DGT NF+ R P AVSI ++ E V+Y L Sbjct: 72 E---SGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNEL 128 Query: 142 YTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGV 201 +T RG+GA NG RLR S DL ++ T P + +++ + +L + A Sbjct: 129 FTATRGQGAQLNGYRLRGSTARDLDGTILATGF-PFKAKQYATTYINIVGKLFNECAD-F 186 Query: 202 RVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRV 261 R GS+ L L ++A+G D +++ GL WD AA +++REAGGIV D +GG ++ + Sbjct: 187 RRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTGNI 246 Query: 262 VAASTREMAMLIAQ 275 VA + R + ++A Sbjct: 247 VAGNPRVVKAMLAN 260 >5ZHH-A nrPDB Length = 270 Score = 130 bits (327), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 75/225 (33%), Positives = 116/225 (51%), Gaps = 5/225 (2%) Query: 41 EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWII 100 E ++ K DLVT D E +++ +R FP H +AEE+ G + + W I Sbjct: 30 EDAITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGNQ---DNEYLWAI 86 Query: 101 DPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVS 160 DP+DGT N+ H++P VSIG + + GVIY + L+ G G GA N + ++VS Sbjct: 87 DPLDGTTNYAHQYPAFCVSIGLLINGVPQVGVIYDPFHDELFRGAAGLGATRNRRPIKVS 146 Query: 161 GETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAAD 220 ++LSK+L++T R + + L H GVR GS+ L L H+A G D Sbjct: 147 DTSELSKSLLVTGFAYDRRETPDNNY-AEFCHLTHL-TQGVRRSGSAALDLAHVACGRVD 204 Query: 221 AYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAAS 265 Y++ G+ WD+ A +++ EAGG V PL + R++A + Sbjct: 205 GYWERGISPWDVVAGVILLEEAGGKVTAYDSTPLKIATGRILATN 249 >2P3V-A nrPDB Length = 256 Score = 127 bits (318), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 122/230 (53%), Gaps = 16/230 (6%) Query: 23 AVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEE 82 +++L + G ++ V KT D+VTE D + +I+ E+R+ FP +AEE Sbjct: 7 SIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDENIMAEE 66 Query: 83 AAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYH-CTEERL 141 + WIIDPIDGT NFVH P ++S+ + E++ GV++ E L Sbjct: 67 GIFEKGDRL------WIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPALNETL 120 Query: 142 YTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGV 201 Y G GAF NG+R+RVS L + + T G D T K F+ ME+ + + Sbjct: 121 YA-EEGSGAFFNGERIRVSENASLEECVGST--GSYVD-FTGK-FIERMEK----RTRRI 171 Query: 202 RVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSG 251 R++GS+ L ++ +G D + + ++ WD+AA +I++EAGG+V D SG Sbjct: 172 RILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSG 221 >2PCR-A nrPDB Length = 264 Score = 123 bits (309), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 68/220 (30%), Positives = 115/220 (52%), Gaps = 7/220 (3%) Query: 27 ALRAGQIIRKALTEEKRVSTKTSA-ADLVTETDHLVEDLIISELRERFPSHRFIAEEAAA 85 AL GQ++++ + K+ + + D V+ D E+ I + + FP H + EE A Sbjct: 15 ALAGGQVLKENFGKVKKENIEEKGEKDFVSYVDKTSEERIKEVILKFFPDHEVVGEEMGA 74 Query: 86 SGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGR 145 G+ W IDP+DGT N+++ FP AVS+G +E G +Y ++LY G Sbjct: 75 EGSGS----EYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAVYLPYFDKLYWGA 130 Query: 146 RGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIG 205 +G GA+ NG+R++V L A V+ P R + ++L N+ + + + +R G Sbjct: 131 KGLGAYVNGKRIKVKDNESLKHAGVVYGF-PSRSRRDISIYL-NIFKDVFYEVGSMRRPG 188 Query: 206 SSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGI 245 ++ + LC +A G D +F + WD+ A VI++EAGG+ Sbjct: 189 AAAVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGV 228 >3LV0-A nrPDB Length = 267 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 81/266 (30%), Positives = 137/266 (51%), Gaps = 9/266 (3%) Query: 15 PWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSA-ADLVTETDHLVEDLIISELRERF 73 P VQ A++AG+ + + E + + AD V++ D E +I +EL + Sbjct: 6 PQSAVMNVMVQAAMKAGRSLVRDYGEVQNLQVSLKGPADYVSQADRKAEKIIFNELSKAR 65 Query: 74 PSHRFIAEEAAASGAKCVLTHSP-TWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 P F+ EE+ + + S +I+DP+DGT NF+H P AVSI + ++ GV Sbjct: 66 PKFGFLMEESE----EIIGEDSQHRFIVDPLDGTTNFLHGIPFFAVSIALESQGKIVAGV 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 IY+ + L+T RG GAF N +R RVS L ++ T + P +L + Sbjct: 122 IYNPINDELFTAERGSGAFFNDRRCRVSARRRLEDCVIATGM-PHLGRPGHGTYLIELRN 180 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 ++ A+ G+R G++ L L ++A+G D +++ L WD+AA +++REAGG V D GG Sbjct: 181 VM-AEVSGIRRFGTAALDLAYVAAGRTDGFWEDNLQIWDMAAGILMVREAGGFVTDKEGG 239 Query: 253 PLDLMACRVVAASTREMAMLIAQALQ 278 D+ + + A + + + +AL+ Sbjct: 240 N-DIFRKKNIIAGNEHIRIKLERALK 264 >5J16-A nrPDB Length = 283 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 116/250 (46%), Gaps = 7/250 (2%) Query: 26 LALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAA 85 L AG I++ + + + TK++ DLVT D ED I + E +P+H+ + EE Sbjct: 18 LIQEAGIRIKQLMEQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPNHQVLGEEG-- 75 Query: 86 SGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGR 145 G + W++DPIDGT NFVH+ A+SIG + + G +Y + LY + Sbjct: 76 HGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAK 135 Query: 146 RGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIG 205 G GA+ Q L+ +++L ++++ I P K L + + + + R G Sbjct: 136 VGEGAYRGSQPLKPLNDSNLRQSII--GINPN---WLTKPILGEIFKEIVNDSRSARAYG 190 Query: 206 SSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAAS 265 S+ L + +A+G +AY L WD A VI+ E G + G PL + + Sbjct: 191 SAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVG 250 Query: 266 TREMAMLIAQ 275 R + I+ Sbjct: 251 NRGLHQEISN 260 >1G0H-A nrPDB Length = 252 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 61/229 (26%), Positives = 112/229 (48%), Gaps = 29/229 (12%) Query: 58 DHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTW--IIDPIDGTCNFVHRFPT 115 D + ED+ + L+ + ++EE V+ +S W +IDPIDG+ NF++ P Sbjct: 44 DKISEDIALKYLKSL--NVNIVSEELG------VIDNSSEWTVVIDPIDGSFNFINGIPF 95 Query: 116 VAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIG 175 A G E +G+ Y + Y +G+GA+ NG++++V D + ++ Sbjct: 96 FAFCFGVFKNNEPYYGLTYEFLTKSFYEAYKGKGAYLNGRKIKVK---DFNPNNIVISYY 152 Query: 176 PKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF--GLHCWDLA 233 P + ++E+ L K VR+ G+ L +C++A G DA + + D+A Sbjct: 153 PSKK--------IDLEK-LRNKVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIA 203 Query: 234 AATVIIREAGGIVIDTSGGPL--DLMAC---RVVAASTREMAMLIAQAL 277 ++ +I +EAG ++ D +G L DL A ++ A+++EM +I L Sbjct: 204 SSYIICKEAGALITDENGDELKFDLNATDRLNIIVANSKEMLDIILDLL 252 >2Q74-A nrPDB Length = 299 Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 71/208 (34%), Positives = 97/208 (46%), Gaps = 18/208 (8%) Query: 34 IRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLT 93 I +A + V K+S D VT D E L+ L + P + EE G +T Sbjct: 36 ISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEG---GGPADVT 92 Query: 94 HSP----TWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRG 149 +P TW++DPIDGT NFV+ P AVSIG V G + +Y+ G G Sbjct: 93 ATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLG 152 Query: 150 AFCNGQR----LRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAK--AHGVRV 203 A +R LR +G +LS AL+ T G +++ E L H VR Sbjct: 153 AHLTDERGRHVLRCTGVDELSMALLGTGFG-----YSVRCREKQAELLAHVVPLVRDVRR 207 Query: 204 IGSSTLALCHLASGAADAYYQFGLHCWD 231 IGS+ L LC +A+G DAYY+ G+ WD Sbjct: 208 IGSAALDLCMVAAGRLDAYYEHGVQVWD 235 >1XI6-A nrPDB Length = 262 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 65/238 (27%), Positives = 107/238 (44%), Gaps = 27/238 (11%) Query: 48 TSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTC 107 + + D D L EDLI+S + E ++EE + T I+DP+DG+ Sbjct: 45 SPSGDETKLVDKLAEDLILSRITEL--GVNVVSEEVGVIDNES----EYTVIVDPLDGSY 98 Query: 108 NFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSK 167 NF+ P A+S+ + + + +IY ER + G G GAF NG+R++V D Sbjct: 99 NFIAGIPFFALSLAVFKKDKPIYAIIYEPMTERFFEGIPGEGAFLNGKRIKVRKTPDEKP 158 Query: 168 ALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGL 227 ++ G E + H K R +G+ L L +LA GA D Sbjct: 159 SISFYSRG------------KGHEIVKHVKR--TRTLGAIALELAYLAMGALDGVVDVRK 204 Query: 228 HC--WDLAAATVIIREAGGIVIDTSGGPLDLMA-----CRVVAASTREMAMLIAQALQ 278 + D+AA T+I +EAG ++ D++G +D+ V+A ++ E+ I L+ Sbjct: 205 YVRPTDIAAGTIIAKEAGALIKDSAGKDIDISFNATDRLDVIAVNSEELLKTILSLLE 262 >1VDW-A nrPDB Length = 254 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 62/238 (26%), Positives = 110/238 (46%), Gaps = 28/238 (11%) Query: 48 TSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTC 107 + + D D + E++IIS+ ++ ++EE + T ++DP+DG+ Sbjct: 37 SPSGDETKVVDKVAENIIISKFKDL--GVNVVSEEIG----RIDQGSDYTVVVDPLDGSY 90 Query: 108 NFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSK 167 NF++ P AVS+ ++ + IY ERLY G G+G++ NG++++V Sbjct: 91 NFINGIPFFAVSVAIFHEKDPIYAFIYEPIVERLYEGIPGKGSYLNGEKIKVR------- 143 Query: 168 ALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF-- 225 E+ K ++ + + K R +G+ L L +LA GA DA Sbjct: 144 -----ELAEK---PSISFYTKGKGTKIIDKVKRTRTLGAIALELAYLARGALDAVVDIRN 195 Query: 226 GLHCWDLAAATVIIREAGGIVIDTSGGPLDLM-----ACRVVAASTREMAMLIAQALQ 278 L D+AA VI REAG IV D G +++ ++AA+ E+ I ++++ Sbjct: 196 YLRPTDIAAGVVIAREAGAIVKDLDGKDVEITFSATEKVNIIAANNEELLETILRSIE 253 >3QMF-A nrPDB Length = 273 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 54/205 (26%), Positives = 88/205 (42%), Gaps = 20/205 (9%) Query: 32 QIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCV 91 Q+I + TE KR DLVT D ++ L FP H+ +AEE + + Sbjct: 34 QLIMEMTTETKR-----HRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNE 88 Query: 92 LTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAF 151 + H WI+DPIDGT N V + + + + + +Y ++LY RG GAF Sbjct: 89 INH--LWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAF 146 Query: 152 CNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERL--LHAKAHGVRVIGSSTL 209 CNG ++ L A++ + + N++ + L + R++G+ L Sbjct: 147 CNGIKMEEPPSLKLEDAII-----------SFNAQVMNLDTVQDLFDASFSYRLVGACGL 195 Query: 210 ALCHLASGAADAYYQFGLHCWDLAA 234 +A G A+ WD+AA Sbjct: 196 DSMRVAKGQFGAHINTNPKPWDIAA 220 >5YHT-A nrPDB Length = 267 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/241 (30%), Positives = 103/241 (42%), Gaps = 22/241 (9%) Query: 23 AVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAE 81 A+ LA RA ++ R + R+ TK VT+ D VE + L P + E Sbjct: 16 ALALADRADELTRVRFGALDLRIDTKPDLTP-VTDADRAVESDVRQTLGRDRPGDGVLGE 74 Query: 82 EAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERL 141 E G T WI+DPIDGT NFV P A I GV+ +R Sbjct: 75 E---FGGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRR 130 Query: 142 YTGRRGRGAFCN-----GQRLRVS--GETDLSKALVLTEIGPKRDPATLKLFLSNMERLL 194 + RGRGAF + RL VS E + + G R P + F+ + + Sbjct: 131 WWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWAR-PGLRERFIGLTDTVW 189 Query: 195 HAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIV--IDTSGG 252 +A+G L+ C +A GA D + + WDLAA +++REAGG + +D G Sbjct: 190 RVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAG 243 Query: 253 P 253 P Sbjct: 244 P 244 >5EQA-A nrPDB Length = 277 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 108/264 (40%), Gaps = 25/264 (9%) Query: 30 AGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAK 89 AG +IRK + + VT D E+ ++S + + FPSH EE G + Sbjct: 28 AGDVIRKYFRKNNFDIIHKNDLSPVTIADQSAEEAMVSVILDNFPSHAVYGEE---KGWR 84 Query: 90 CVLTHSP-TWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGR 148 C + W++DPIDGT +F+ P I G+I + + G G+ Sbjct: 85 CKQDSADYVWVLDPIDGTKSFITGKPLFGTLIALLQNGTPILGIIDQPVLKERWIGITGK 144 Query: 149 GAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRV--IGS 206 NGQ + DLS+A + T + LF + E V++ G Sbjct: 145 RTTLNGQEVSTRTCADLSQAYLYT--------TSPHLFSGDAEEAFIRVRDKVKIPLYGC 196 Query: 207 STLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSG-------GPLDL-MA 258 A L+SG D + GL +D A +I +GG++ D G PL + + Sbjct: 197 DCYAYALLSSGFVDLVVESGLKPYDFLALIPVIEGSGGVITDWKGHQLRWEASPLSIATS 256 Query: 259 CRVVAASTREMAMLIAQALQTINY 282 VVAA +++ QAL ++ + Sbjct: 257 FNVVAAGDKQIHQ---QALDSLQW 277 >1JP4-A nrPDB Length = 308 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 104/271 (38%), Gaps = 52/271 (19%) Query: 22 AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 +A +A +AG I+R + E + + KTSA DL T+ D +V+ I S L +FP I Sbjct: 14 SAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLSRKFPKLTIIG 73 Query: 81 EEAAASG-----------------AKCVLTHSP-------TWIIDPIDGTCNFVH-RFPT 115 EE G C +S W+ DP+DGT + Sbjct: 74 EEDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWV-DPVDGTKEYTEGLLDN 132 Query: 116 VAVSIGFAVRQELEFGVI---YHCTEE-------RLYTGRRGRGAFCNGQRLRVSGETDL 165 V V IG A + G+I Y+ + R G G GAF G +L+ E Sbjct: 133 VTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAF--GFQLK---EAPA 187 Query: 166 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 225 K ++ T T + N + +L G ++I L G A AY Sbjct: 188 GKHIITTTRSHSNKLVTDCIAAMNPDNVLRVGGAGNKII--------QLIEGKASAYVFA 239 Query: 226 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 254 C WD A VI+ GG + D G PL Sbjct: 240 SPGCKKWDTCAPEVILHAVGGKLTDIHGNPL 270 >1LBZ-A nrPDB Length = 252 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 85/205 (41%), Gaps = 35/205 (17%) Query: 58 DHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVA 117 D + ED + LR+ + + EE+ G V +DP+DGT N P + Sbjct: 46 DRVAEDAALEILRKERVT--VVTEESGVLGEGDVFVA-----LDPLDGTFNATRGIPVYS 98 Query: 118 VSIGFAVRQELE---FGVIYH-CTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTE 173 VS+ F+ +L+ FG +Y+ T + Y GA+ NG+R+ VS +L ++ Sbjct: 99 VSLCFSYSDKLKDAFFGYVYNLATGDEYYAD--SSGAYRNGERIEVSDAEELYCNAIIYY 156 Query: 174 IGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFG----LHC 229 P R K M R+ GS+ LC A G+ D + L Sbjct: 157 --PDR-----KFPFKRM-----------RIFGSAATELCFFADGSFDCFLDIRPGKMLRI 198 Query: 230 WDLAAATVIIREAGGIVIDTSGGPL 254 +D AA I +AGG V + G L Sbjct: 199 YDAAAGVFIAEKAGGKVTELDGESL 223 >4O7I-A nrPDB Length = 325 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 74/295 (25%), Positives = 114/295 (38%), Gaps = 61/295 (20%) Query: 20 FQAAVQLALRAGQIIRK--------ALTEEKRVSTKTSAADLVTETDHLVEDLIISELRE 71 F + LAL Q+ K LT++ ++ S VT D+ V+ + ++ E Sbjct: 3 FDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSP---VTVGDYSVQAYVNKKIHE 59 Query: 72 RFPSHRFIAEEAA--------ASGAKCVLTHSPT---------------------WIIDP 102 FP + +AEE A K V +S W++DP Sbjct: 60 TFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDP 119 Query: 103 IDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEE--RLYTGRRGRGA-------FCN 153 IDGT F+ R AV + F + +++ GV+ E + ++G GA N Sbjct: 120 IDGTLGFLRR-EQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKN 178 Query: 154 GQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCH 213 G+ + VS S + + ++ ERL K VR+ S Sbjct: 179 GKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTIT--ERLQVTKP-PVRM--DSQCKYMA 233 Query: 214 LASGAADAYYQ------FGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVV 262 +ASG AD Y + + WD AA +I++EAGG V D G LD R + Sbjct: 234 IASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTL 288 >3B8B-A nrPDB Length = 292 Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 64/227 (28%), Positives = 95/227 (41%), Gaps = 21/227 (9%) Query: 22 AAVQLALRAGQIIRKALTEEKRVSTKTSAAD--LVTETDHLVEDLIISELRER-FPSHRF 78 AA+ AL+AG+ I + K AD +T D + I++ L E FP Sbjct: 26 AAIDAALKAGEKILSIYEDPKSDFEIERKADNSPLTIADRKAHEAIVAILNETPFP---V 82 Query: 79 IAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTE 138 ++EE WI+DP+DGT F+ R V+I GVIY + Sbjct: 83 LSEEGKHMDYAVRRGWDTLWIVDPLDGTKEFIKRNGEFTVNIALVQNAVPVMGVIYVPVK 142 Query: 139 ERLYTGRRGRGAF-CNG-QRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERL--- 193 + LY G GA+ C+G L G T L + + +E P D + +++ L Sbjct: 143 KELYFAVEGTGAYKCSGIVGLEDEGVT-LQQMIEKSERMPLADARDHFIAVASRSHLTPE 201 Query: 194 -------LHAKAHGVRVIGS-STLALCHLASGAADAYYQFGLHC-WD 231 L K V +I S S++ +C +A G AD Y +F WD Sbjct: 202 TETYIADLKKKHGNVELISSGSSIKICLVAEGKADVYPRFAPTMEWD 248 >2WEF-A nrPDB Length = 311 Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 102/271 (37%), Gaps = 52/271 (19%) Query: 22 AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 +A +A +AG I+R+ + E + + KT A DL T+ D L + I S L +FP I Sbjct: 10 SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 69 Query: 81 EEAAAS-----------------GAKCVLTHSP-------TWIIDPIDGTCNFVH-RFPT 115 EE S C +S W+ DP+DGT + Sbjct: 70 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTEGLLDN 128 Query: 116 VAVSIGFAVRQELEFGVI---YHCTEE-------RLYTGRRGRGAFCNGQRLRVSGETDL 165 V V IG A + GVI Y+ E R G G GAF G +L+ E Sbjct: 129 VTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLK---EVPA 183 Query: 166 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 225 K ++ T T + N + +L G ++I L G A AY Sbjct: 184 GKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKII--------QLIEGKASAYVFA 235 Query: 226 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 254 C WD A VI+ GG + D G L Sbjct: 236 SPGCKKWDTCAPEVILHAVGGKLTDIHGNVL 266 >4N81-A nrPDB Length = 259 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 60/259 (23%), Positives = 96/259 (37%), Gaps = 20/259 (7%) Query: 16 WEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPS 75 +E+ + A +LA A IIR + K + VT+ D E + + L + P Sbjct: 6 YEDDIRLAHRLADVAADIIRPFFRAPLTIDLKADHSP-VTKADRGAEQAMRAILEQERPE 64 Query: 76 HRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYH 135 EE S W++DPIDGT F+ + I G+I Sbjct: 65 DGIFGEEMGVSRPDA----RRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGIINQ 120 Query: 136 CTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLH 195 + + G + NG+ + L AL+ AT +L E +H Sbjct: 121 PIHQERWVGVKDLPTSFNGEVIHTRSCPALDHALL----------ATTSPWLFEKEGEVH 170 Query: 196 AKAHGVR----VIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSG 251 ++ ++G L+ G D + GL +D AA I+ AGGI+ D Sbjct: 171 FDKIRLKCRDTLLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIMRDWQN 230 Query: 252 GPLDLMAC-RVVAASTREM 269 PL+ + V+AA + Sbjct: 231 RPLNKNSVGEVIAAGDHHL 249 >4QXD-A nrPDB Length = 293 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 44/241 (18%) Query: 38 LTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPT 97 EE + K+ ++ VT+ D + +I S ++ ++P+ I EE +G + T Sbjct: 26 FKEEVEIKYKSDGSE-VTQVDTQSQQIIFSIIKNKYPTINIIGEEDVENGIPDNQLPTIT 84 Query: 98 WI------------------IDPIDGTCNFVHR-FPTVAVSIGFAVRQELEFGVIYHCTE 138 + +DP+DGT + H+ + +V V +G + + G++ Sbjct: 85 QLSFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCVLVGVTYKGKPMIGIV----- 139 Query: 139 ERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSN-MERLLHA- 196 F N + + + E +S + P D N ++ L+ + Sbjct: 140 ---------SKPFYNNE-ITFAIENYISS----ISLQPLNDKIIFVCSKKNDIQHLIKSF 185 Query: 197 -KAHGVRVIGSSTLALCHLASGAADAYYQFGLHC--WDLAAATVIIREAGGIVIDTSGGP 253 + V+ G S + + AD YY + WD AA VI+ GGIV D G P Sbjct: 186 PDPYEVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQVILEAQGGIVCDIYGNP 245 Query: 254 L 254 L Sbjct: 246 L 246 >5ESY-A nrPDB Length = 346 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/225 (23%), Positives = 86/225 (38%), Gaps = 53/225 (23%) Query: 98 WIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVI----------------YHCTEER- 140 W++DPIDGT F+ R AV++G ++ GV+ ++E Sbjct: 131 WVLDPIDGTKGFL-RGDQYAVALGLLEEGKVVLGVLACPNLPLASIAGNNKNKSSSDEIG 189 Query: 141 -LYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLF------------L 187 L+ G G + Q L D + V ++ +P F Sbjct: 190 CLFFATIGSGTYM--QLL------DSKSSPVKVQVSSVENPEEASFFESFEGAHSLHDLS 241 Query: 188 SNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFG-----LHCWDLAAATVIIREA 242 S++ L KA VR+ S L+ G Y +F WD A +++ EA Sbjct: 242 SSIANKLGVKAPPVRI--DSQAKYGALSRGDGAIYLRFPHKGYREKIWDHVAGAIVVTEA 299 Query: 243 GGIVIDTSGGPLDLMACR-------VVAASTREMAMLIAQALQTI 280 GGIV D +G PLD + ++ A+ + M +L+ +I Sbjct: 300 GGIVTDAAGKPLDFSKGKYLDLDTGIIVANEKLMPLLLKAVRDSI 344 >1KA0-A nrPDB Length = 357 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/199 (27%), Positives = 73/199 (36%), Gaps = 43/199 (21%) Query: 98 WIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIY----------------HCTEERL 141 W +DPIDGT F+ R AV + V ++ G I H + + Sbjct: 139 WCLDPIDGTKGFL-RGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYI 197 Query: 142 YTGRRGRGAFCNGQ-------RLRVSGETDLSKALVL--TEIG-PKRDPATLKLFLSNME 191 + RG GAF + ++ V D + L E G D T N+ Sbjct: 198 FRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNIS 257 Query: 192 RLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLH------CWDLAAATVIIREAGGI 245 + LH S C LA G AD Y + + WD AA VI+ EAGGI Sbjct: 258 KSLHL---------DSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGI 308 Query: 246 VIDT-SGGPLDLMACRVVA 263 D PLD R +A Sbjct: 309 HTDAMEDVPLDFGNGRTLA 327 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 11/69 (15%) Query: 28 LRAGQIIRKALTEEKRV---------STKTSAADL--VTETDHLVEDLIISELRERFPSH 76 L A Q +RKA KR+ ST + D VT D+ + +II+ ++ FP Sbjct: 8 LVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDD 67 Query: 77 RFIAEEAAA 85 + + EE+++ Sbjct: 68 KVVGEESSS 76 >5DJK-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust. Identities = 57/228 (25%), Positives = 77/228 (33%), Gaps = 51/228 (22%) Query: 58 DHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVA 117 D L++ L+ P ++EEA A+ L WIIDP+DGT F + Sbjct: 71 DRQANSLLLRRLQAERPGDAVLSEEAHDDLAR--LKSDRVWIIDPLDGTREF-----STP 123 Query: 118 VSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQR--------LRVSGETDLSKAL 169 +AV L RR NGQ L G Sbjct: 124 GRDDWAVHIALW---------------RRS----SNGQPEITDAAVALPARGNVVYRTDT 164 Query: 170 VLTEIGPKRDPATLKLFLSN------MERLLHAKAHGVRVIGSSTLALCHLASGAADAYY 223 V + P P TL++ +S + R+ A IGS+ + G DAY Sbjct: 165 VTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYL 224 Query: 224 QFGLHC-WDLAAATVIIREAGGIVIDTSGGPL----------DLMACR 260 G WD AA ++ AG G PL DL+ CR Sbjct: 225 HAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCR 272 >6AAE-A nrPDB Length = 317 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Query: 61 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWII---DPIDGTCNFVHRFPTVA 117 VE++ IS + ++ E+A A V H W+I D DGTC + + A Sbjct: 46 VENIAISLDGRDLDARLYVPEDADERPALMVYYHGGGWVIGTLDTHDGTCRALAQKSGCA 105 Query: 118 V-SIGFAVRQELEFGVIYH-CTEERLYTGRRGRGAFCNGQRLRVSGET 163 V SI + + E + C + ++ + +G RL V G++ Sbjct: 106 VLSIAYRLAPEYRYPAPAEDCYDALVWAKQNAATLGVDGDRLAVGGDS 153 >3KRZ-A nrPDB Length = 337 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Query: 24 VQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISE 68 V + L G ++ A T +KR + KTSA L+T T L E+++ +E Sbjct: 256 VDINLYPGYQVKYAETIKKRCNIKTSAVGLIT-TQELAEEILSNE 299 >4MH4-A nrPDB Length = 147 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 4 SGEDQAALAAGPWEECFQAAVQLALRAGQI 33 +G + L A W CF A+QLA RA ++ Sbjct: 51 TGTNPEQLFAAGWSACFIGAMQLAARAAKV 80 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2CZH-A nrPDB 393 e-110 1IMD-A nrPDB 365 e-101 4AS5-A nrPDB 362 e-101 2BJI-A nrPDB 362 e-100 6IB8-A nrPDB 264 3e-71 5ZHH-A nrPDB 259 9e-70 5J16-A nrPDB 257 3e-69 3LV0-A nrPDB 248 3e-66 2PCR-A nrPDB 243 9e-65 2P3V-A nrPDB 236 9e-63 4N81-A nrPDB 233 7e-62 5EQA-A nrPDB 232 2e-61 1VDW-A nrPDB 204 2e-53 1XI6-A nrPDB 199 1e-51 4O7I-A nrPDB 195 2e-50 1G0H-A nrPDB 189 8e-49 1JP4-A nrPDB 187 4e-48 5YHT-A nrPDB 187 5e-48 3QMF-A nrPDB 186 9e-48 2WEF-A nrPDB 182 2e-46 4QXD-A nrPDB 172 1e-43 2Q74-A nrPDB 168 2e-42 3B8B-A nrPDB 167 6e-42 1KA0-A nrPDB 162 1e-40 1LBZ-A nrPDB 157 5e-39 5ESY-A nrPDB 141 3e-34 Sequences not found previously or not previously below threshold: 5DJK-A nrPDB 81 5e-16 1INP-A nrPDB 64 6e-11 2F3D-A nrPDB 39 0.002 2FHY-A nrPDB 39 0.002 1BK4-A nrPDB 38 0.005 5Q0C-A nrPDB 36 0.022 2QVR-A nrPDB 34 0.054 5FGU-A nrPDB 34 0.11 1SPI-A nrPDB 33 0.19 1DCU-A nrPDB 32 0.21 5IZ1-A nrPDB 32 0.28 6N9G-C nrPDB 32 0.33 4JG5-A nrPDB 30 1.7 3CMG-A nrPDB 29 2.2 6HHQ-h nrPDB 29 2.4 4ZSG-A nrPDB 29 3.5 4IC8-A nrPDB 29 3.5 5EUA-A nrPDB 29 3.6 4MKS-A nrPDB 28 4.1 5OQL-J nrPDB 28 4.3 3FN9-A nrPDB 28 4.3 4LJ8-A nrPDB 28 5.1 3BRN-A nrPDB 28 5.1 1QVR-A nrPDB 28 6.2 >2CZH-A nrPDB Length = 299 Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL 60 MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL Sbjct: 12 MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL 71 Query: 61 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI 120 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI Sbjct: 72 VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI 131 Query: 121 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP 180 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP Sbjct: 132 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP 191 Query: 181 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR 240 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR Sbjct: 192 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR 251 Query: 241 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK 288 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK Sbjct: 252 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK 299 >1IMD-A nrPDB Length = 277 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 147/275 (53%), Positives = 209/275 (76%) Query: 13 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72 A PW+EC AV LA +AG+++ +A+ E V K+S DLVT TD VE ++IS ++E+ Sbjct: 2 ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61 Query: 73 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV Sbjct: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y C E ++YT R+G+GAFCNGQ+L+VS + D++K+L++TE+G R P T+++ LSNME+ Sbjct: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 L HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 P DLM+ RV+AA+ R +A IA+ +Q I RDDE Sbjct: 242 PFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 >4AS5-A nrPDB Length = 277 Score = 362 bits (930), Expect = e-101, Method: Composition-based stats. Identities = 146/275 (53%), Positives = 209/275 (76%) Query: 13 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72 A PW+EC AV LA +AG++IR+AL E V K+S ADLVT TD VE +++S ++E+ Sbjct: 2 ADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEK 61 Query: 73 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 +P H FI EE+ A+G K V T PTW+IDPIDGT NFVHRFP VAVSIGF V +E+EFG+ Sbjct: 62 YPCHSFIGEESVAAGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGI 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y C E+++YTGR+G+GAFCNGQ+L+VS + D++K+L++TE+G R P TL++ LSNME+ Sbjct: 122 VYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEK 181 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 L HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 182 LCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGG 241 Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 P DLM+ R++AA++ +A IA+ ++ I RDDE Sbjct: 242 PFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDE 276 >2BJI-A nrPDB Length = 277 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 148/275 (53%), Positives = 213/275 (77%) Query: 13 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72 A PW+EC AV LA +AG+++R+AL E + K+S ADLVT TD VE ++I+ ++E+ Sbjct: 2 ADPWQECMDYAVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKEK 61 Query: 73 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132 +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVH FP VAVSIGF V +++EFG+ Sbjct: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFGI 121 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y C E+++YTGR+G+GAFCNGQ+L+VS + D++K+L++TE+G R P T+++ LSN+ER Sbjct: 122 VYSCLEDKMYTGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIER 181 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252 LL HG+R +G++ L +C +A+GAADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 182 LLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTGG 241 Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 P DLM+ RV+A+S + +A IA+ +Q I RDDE Sbjct: 242 PFDLMSRRVIASSNKTLAERIAKEIQIIPLQRDDE 276 >6IB8-A nrPDB Length = 271 Score = 264 bits (674), Expect = 3e-71, Method: Composition-based stats. Identities = 89/273 (32%), Positives = 137/273 (50%), Gaps = 9/273 (3%) Query: 9 AALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVS-TKTSAADLVTETDHLVEDLIIS 67 A+A P AV+ A +AG +I K V ++ + D VT D E +II Sbjct: 1 GAMAMHP---MLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIID 57 Query: 68 ELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQE 127 +R+ +P H I EE+ G W+IDP+DGT NF+ R P AVSI ++ Sbjct: 58 TIRKSYPQHTIITEES---GELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGR 114 Query: 128 LEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFL 187 E V+Y L+T RG+GA NG RLR S DL ++ T P + ++ Sbjct: 115 TEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGF-PFKAKQYATTYI 173 Query: 188 SNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVI 247 + + +L + A R GS+ L L ++A+G D +++ GL WD AA +++REAGGIV Sbjct: 174 NIVGKLFNECAD-FRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVS 232 Query: 248 DTSGGPLDLMACRVVAASTREMAMLIAQALQTI 280 D +GG ++ +VA + R + ++A + Sbjct: 233 DFTGGHNYMLTGNIVAGNPRVVKAMLANMRDEL 265 >5ZHH-A nrPDB Length = 270 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 77/241 (31%), Positives = 122/241 (50%), Gaps = 6/241 (2%) Query: 41 EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWII 100 E ++ K DLVT D E +++ +R FP H +AEE+ G + W I Sbjct: 30 EDAITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGN---QDNEYLWAI 86 Query: 101 DPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVS 160 DP+DGT N+ H++P VSIG + + GVIY + L+ G G GA N + ++VS Sbjct: 87 DPLDGTTNYAHQYPAFCVSIGLLINGVPQVGVIYDPFHDELFRGAAGLGATRNRRPIKVS 146 Query: 161 GETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAAD 220 ++LSK+L++T R + + L H GVR GS+ L L H+A G D Sbjct: 147 DTSELSKSLLVTGFAYDRRETPDNNY-AEFCHLTHL-TQGVRRSGSAALDLAHVACGRVD 204 Query: 221 AYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTI 280 Y++ G+ WD+ A +++ EAGG V PL + R++A + + +++AL + Sbjct: 205 GYWERGISPWDVVAGVILLEEAGGKVTAYDSTPLKIATGRILATNG-SIHDNLSRALMQV 263 Query: 281 N 281 Sbjct: 264 P 264 >5J16-A nrPDB Length = 283 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 115/253 (45%), Gaps = 7/253 (2%) Query: 23 AVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEE 82 A L AG I++ + + + TK++ DLVT D ED I + E +P+H+ + EE Sbjct: 15 AQGLIQEAGIRIKQLMEQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPNHQVLGEE 74 Query: 83 AAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLY 142 G + W++DPIDGT NFVH+ A+SIG + + G +Y + LY Sbjct: 75 G--HGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLY 132 Query: 143 TGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVR 202 + G GA+ Q L+ +++L ++++ K L + + + + R Sbjct: 133 HAKVGEGAYRGSQPLKPLNDSNLRQSIIGI-----NPNWLTKPILGEIFKEIVNDSRSAR 187 Query: 203 VIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVV 262 GS+ L + +A+G +AY L WD A VI+ E G + G PL + + Sbjct: 188 AYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSI 247 Query: 263 AASTREMAMLIAQ 275 R + I+ Sbjct: 248 LVGNRGLHQEISN 260 >3LV0-A nrPDB Length = 267 Score = 248 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 80/265 (30%), Positives = 135/265 (50%), Gaps = 7/265 (2%) Query: 15 PWEECFQAAVQLALRAGQIIRKALTEEKRVSTK-TSAADLVTETDHLVEDLIISELRERF 73 P VQ A++AG+ + + E + + AD V++ D E +I +EL + Sbjct: 6 PQSAVMNVMVQAAMKAGRSLVRDYGEVQNLQVSLKGPADYVSQADRKAEKIIFNELSKAR 65 Query: 74 PSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVI 133 P F+ EE+ + +I+DP+DGT NF+H P AVSI + ++ GVI Sbjct: 66 PKFGFLMEESEEIIGEDSQ---HRFIVDPLDGTTNFLHGIPFFAVSIALESQGKIVAGVI 122 Query: 134 YHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERL 193 Y+ + L+T RG GAF N +R RVS L ++ T + P +L + + Sbjct: 123 YNPINDELFTAERGSGAFFNDRRCRVSARRRLEDCVIATGM-PHLGRPGHGTYLIELRNV 181 Query: 194 LHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGP 253 + A+ G+R G++ L L ++A+G D +++ L WD+AA +++REAGG V D GG Sbjct: 182 M-AEVSGIRRFGTAALDLAYVAAGRTDGFWEDNLQIWDMAAGILMVREAGGFVTDKEGGN 240 Query: 254 LDLMACRVVAASTREMAMLIAQALQ 278 D+ + + A + + + +AL+ Sbjct: 241 -DIFRKKNIIAGNEHIRIKLERALK 264 >2PCR-A nrPDB Length = 264 Score = 243 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 125/258 (48%), Gaps = 11/258 (4%) Query: 20 FQAAVQLALRAGQIIRKALTEEKRVSTKTSA-ADLVTETDHLVEDLIISELRERFPSHRF 78 + A AL GQ++++ + K+ + + D V+ D E+ I + + FP H Sbjct: 8 LEVAKIAALAGGQVLKENFGKVKKENIEEKGEKDFVSYVDKTSEERIKEVILKFFPDHEV 67 Query: 79 IAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTE 138 + EE A G W IDP+DGT N+++ FP AVS+G +E G +Y Sbjct: 68 VGEEMGAEG----SGSEYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAVYLPYF 123 Query: 139 ERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKA 198 ++LY G +G GA+ NG+R++V L A V+ P R + ++L N+ + + + Sbjct: 124 DKLYWGAKGLGAYVNGKRIKVKDNESLKHAGVVYGF-PSRSRRDISIYL-NIFKDVFYEV 181 Query: 199 HGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMA 258 +R G++ + LC +A G D +F + WD+ A VI++EAGG+ G P + Sbjct: 182 GSMRRPGAAAVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGVYT-LVGEPFGVSD 240 Query: 259 CRVVAASTREMAMLIAQA 276 + A + + I Q Sbjct: 241 ---IIAGNKALHDFILQV 255 >2P3V-A nrPDB Length = 256 Score = 236 bits (602), Expect = 9e-63, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 120/248 (48%), Gaps = 14/248 (5%) Query: 18 ECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHR 77 + +++L + G ++ V KT D+VTE D + +I+ E+R+ FP Sbjct: 2 DRLDFSIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDEN 61 Query: 78 FIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCT 137 +AEE WIIDPIDGT NFVH P ++S+ + E++ GV++ Sbjct: 62 IMAEEGIFEKG------DRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPA 115 Query: 138 EERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAK 197 G GAF NG+R+RVS L + + T F+ ME+ + Sbjct: 116 LNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFT----GKFIERMEK----R 167 Query: 198 AHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLM 257 +R++GS+ L ++ +G D + + ++ WD+AA +I++EAGG+V D SG + Sbjct: 168 TRRIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAF 227 Query: 258 ACRVVAAS 265 + + ++ Sbjct: 228 SKNFIFSN 235 >4N81-A nrPDB Length = 259 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 60/273 (21%), Positives = 100/273 (36%), Gaps = 20/273 (7%) Query: 11 LAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELR 70 ++ +E+ + A +LA A IIR + K + VT+ D E + + L Sbjct: 1 MSRSAYEDDIRLAHRLADVAADIIRPFFRAPLTIDLKADHS-PVTKADRGAEQAMRAILE 59 Query: 71 ERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEF 130 + P EE S W++DPIDGT F+ + I Sbjct: 60 QERPEDGIFGEEMGVSRP----DARRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVL 115 Query: 131 GVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNM 190 G+I + + G + NG+ + L AL+ T +L Sbjct: 116 GIINQPIHQERWVGVKDLPTSFNGEVIHTRSCPALDHALLATT----------SPWLFEK 165 Query: 191 ERLLHAKAHGVR----VIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIV 246 E +H ++ ++G L+ G D + GL +D AA I+ AGGI+ Sbjct: 166 EGEVHFDKIRLKCRDTLLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIM 225 Query: 247 IDTSGGPLDLMA-CRVVAASTREMAMLIAQALQ 278 D PL+ + V+AA + A++ Sbjct: 226 RDWQNRPLNKNSVGEVIAAGDHHLIEPALSAME 258 >5EQA-A nrPDB Length = 277 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 70/273 (25%), Positives = 110/273 (40%), Gaps = 25/273 (9%) Query: 21 QAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 A + A AG +IRK + + VT D E+ ++S + + FPSH Sbjct: 19 DVANKAANAAGDVIRKYFRKNNFDIIHKNDLSPVTIADQSAEEAMVSVILDNFPSHAVYG 78 Query: 81 EEAAASGAKCVLTH-SPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEE 139 EE G +C W++DPIDGT +F+ P I G+I + Sbjct: 79 EE---KGWRCKQDSADYVWVLDPIDGTKSFITGKPLFGTLIALLQNGTPILGIIDQPVLK 135 Query: 140 RLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAH 199 + G G+ NGQ + DLS+A + T + LF + E Sbjct: 136 ERWIGITGKRTTLNGQEVSTRTCADLSQAYLYTT--------SPHLFSGDAEEAFIRVRD 187 Query: 200 GVRV--IGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSG------ 251 V++ G A L+SG D + GL +D A +I +GG++ D G Sbjct: 188 KVKIPLYGCDCYAYALLSSGFVDLVVESGLKPYDFLALIPVIEGSGGVITDWKGHQLRWE 247 Query: 252 -GPLDL-MACRVVAASTREMAMLIAQALQTINY 282 PL + + VVAA +++ QAL ++ + Sbjct: 248 ASPLSIATSFNVVAAGDKQIHQ---QALDSLQW 277 >1VDW-A nrPDB Length = 254 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 64/267 (23%), Positives = 115/267 (43%), Gaps = 30/267 (11%) Query: 21 QAAVQLALRAGQIIRKALTEEKRVSTKT--SAADLVTETDHLVEDLIISELRERFPSHRF 78 + A+ + I K T + + D D + E++IIS+ ++ Sbjct: 8 KIAIDIIRDFDHNIMPLFGNPKASETISISPSGDETKVVDKVAENIIISKFKDL--GVNV 65 Query: 79 IAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTE 138 ++EE + T ++DP+DG+ NF++ P AVS+ ++ + IY Sbjct: 66 VSEEIG----RIDQGSDYTVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPIV 121 Query: 139 ERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKA 198 ERLY G G+G++ NG++++V + ++ + + K Sbjct: 122 ERLYEGIPGKGSYLNGEKIKVRELAE---------------KPSISFYTKGKGTKIIDKV 166 Query: 199 HGVRVIGSSTLALCHLASGAADAYYQFG--LHCWDLAAATVIIREAGGIVIDTSGGPLDL 256 R +G+ L L +LA GA DA L D+AA VI REAG IV D G +++ Sbjct: 167 KRTRTLGAIALELAYLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDGKDVEI 226 Query: 257 M-----ACRVVAASTREMAMLIAQALQ 278 ++AA+ E+ I ++++ Sbjct: 227 TFSATEKVNIIAANNEELLETILRSIE 253 >1XI6-A nrPDB Length = 262 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 64/267 (23%), Positives = 111/267 (41%), Gaps = 29/267 (10%) Query: 21 QAAVQLALRAGQIIRKALTEEK--RVSTKTSAADLVTETDHLVEDLIISELRERFPSHRF 78 + A+ + I ++ + + D D L EDLI+S + E Sbjct: 16 EVAIDIISDFETTIMPFFGNPDGGKLVKISPSGDETKLVDKLAEDLILSRITEL--GVNV 73 Query: 79 IAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTE 138 ++EE + T I+DP+DG+ NF+ P A+S+ + + + +IY Sbjct: 74 VSEEVGVIDNES----EYTVIVDPLDGSYNFIAGIPFFALSLAVFKKDKPIYAIIYEPMT 129 Query: 139 ERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKA 198 ER + G G GAF NG+R++V D ++ G + Sbjct: 130 ERFFEGIPGEGAFLNGKRIKVRKTPDEKPSISFYSRG--------------KGHEIVKHV 175 Query: 199 HGVRVIGSSTLALCHLASGAADAYYQFG--LHCWDLAAATVIIREAGGIVIDTSGGPLDL 256 R +G+ L L +LA GA D + D+AA T+I +EAG ++ D++G +D+ Sbjct: 176 KRTRTLGAIALELAYLAMGALDGVVDVRKYVRPTDIAAGTIIAKEAGALIKDSAGKDIDI 235 Query: 257 M-----ACRVVAASTREMAMLIAQALQ 278 V+A ++ E+ I L+ Sbjct: 236 SFNATDRLDVIAVNSEELLKTILSLLE 262 >4O7I-A nrPDB Length = 325 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 73/319 (22%), Positives = 117/319 (36%), Gaps = 67/319 (21%) Query: 20 FQAAVQLALRAGQIIRKA--------LTEEKRVSTKTSAADLVTETDHLVEDLIISELRE 71 F + LAL Q+ K LT++ ++ S VT D+ V+ + ++ E Sbjct: 3 FDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSP---VTVGDYSVQAYVNKKIHE 59 Query: 72 RFPSHRFIAEEAA--------ASGAKCVLTHSPT---------------------WIIDP 102 FP + +AEE A K V +S W++DP Sbjct: 60 TFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDP 119 Query: 103 IDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEE--RLYTGRRGRGA-------FCN 153 IDGT F+ R AV + F + +++ GV+ E + ++G GA N Sbjct: 120 IDGTLGFLRR-EQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKN 178 Query: 154 GQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCH 213 G+ + VS S + + ++ L VR+ S Sbjct: 179 GKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITER---LQVTKPPVRM--DSQCKYMA 233 Query: 214 LASGAADAYYQ------FGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRV------ 261 +ASG AD Y + + WD AA +I++EAGG V D G LD R Sbjct: 234 IASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHG 293 Query: 262 VAASTREMAMLIAQALQTI 280 + AS + ++ + Sbjct: 294 IVASNGILHEETVNVVKDV 312 >1G0H-A nrPDB Length = 252 Score = 189 bits (481), Expect = 8e-49, Method: Composition-based stats. Identities = 60/261 (22%), Positives = 114/261 (43%), Gaps = 27/261 (10%) Query: 26 LALRAGQIIRKALTEEKR--VSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEA 83 +A + I + + V + + D D + ED+ + L+ + ++EE Sbjct: 10 IAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSL--NVNIVSEEL 67 Query: 84 AASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYT 143 T +IDPIDG+ NF++ P A G E +G+ Y + Y Sbjct: 68 GVIDNSS----EWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKSFYE 123 Query: 144 GRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRV 203 +G+GA+ NG++++V D + ++ P + ++E+ L K VR+ Sbjct: 124 AYKGKGAYLNGRKIKVK---DFNPNNIVISYYPSKK--------IDLEK-LRNKVKRVRI 171 Query: 204 IGSSTLALCHLASGAADAYYQFGLHC--WDLAAATVIIREAGGIVIDTSGGPLDL----- 256 G+ L +C++A G DA + D+A++ +I +EAG ++ D +G L Sbjct: 172 FGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDELKFDLNAT 231 Query: 257 MACRVVAASTREMAMLIAQAL 277 ++ A+++EM +I L Sbjct: 232 DRLNIIVANSKEMLDIILDLL 252 >1JP4-A nrPDB Length = 308 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 73/271 (26%), Positives = 101/271 (37%), Gaps = 52/271 (19%) Query: 22 AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 +A +A +AG I+R + E + + KTSA DL T+ D +V+ I S L +FP I Sbjct: 14 SAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLSRKFPKLTIIG 73 Query: 81 EEAAASGA-----------------KCVLTHSP-------TWIIDPIDGTCNFVHR-FPT 115 EE G C +S W+ DP+DGT + Sbjct: 74 EEDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWV-DPVDGTKEYTEGLLDN 132 Query: 116 VAVSIGFAVRQELEFGVIYHCTEE----------RLYTGRRGRGAFCNGQRLRVSGETDL 165 V V IG A + G+I R G G GAF G +L+ E Sbjct: 133 VTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAF--GFQLK---EAPA 187 Query: 166 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 225 K ++ T T + N + +L G ++I L G A AY Sbjct: 188 GKHIITTTRSHSNKLVTDCIAAMNPDNVLRVGGAGNKII--------QLIEGKASAYVFA 239 Query: 226 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 254 C WD A VI+ GG + D G PL Sbjct: 240 SPGCKKWDTCAPEVILHAVGGKLTDIHGNPL 270 >5YHT-A nrPDB Length = 267 Score = 187 bits (474), Expect = 5e-48, Method: Composition-based stats. Identities = 70/241 (29%), Positives = 100/241 (41%), Gaps = 18/241 (7%) Query: 18 ECFQAAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSH 76 + A+ LA RA ++ R + R+ TK VT+ D VE + L P Sbjct: 11 DDLMLALALADRADELTRVRFGALDLRIDTKPDLT-PVTDADRAVESDVRQTLGRDRPGD 69 Query: 77 RFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHC 136 + EE G T WI+DPIDGT NFV P A I GV+ Sbjct: 70 GVLGEE---FGGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAP 125 Query: 137 TEERLYTGRRGRGAFCN-----GQRLRVSGETDLSKALVLTEIGPK-RDPATLKLFLSNM 190 +R + RGRGAF + RL VS +L A + P + F+ Sbjct: 126 ALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLT 185 Query: 191 ERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTS 250 + + +A+G L+ C +A GA D + + WDLAA +++REAGG + Sbjct: 186 DTVWRVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLD 239 Query: 251 G 251 G Sbjct: 240 G 240 >3QMF-A nrPDB Length = 273 Score = 186 bits (472), Expect = 9e-48, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 99/250 (39%), Gaps = 20/250 (8%) Query: 32 QIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCV 91 Q+I + TE TK DLVT D ++ L FP H+ +AEE + + Sbjct: 34 QLIMEMTTE-----TKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNE 88 Query: 92 LTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAF 151 + H WI+DPIDGT N V + + + + + +Y ++LY RG GAF Sbjct: 89 INH--LWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAF 146 Query: 152 CNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERL--LHAKAHGVRVIGSSTL 209 CNG ++ L A++ + + N++ + L + R++G+ L Sbjct: 147 CNGIKMEEPPSLKLEDAII-----------SFNAQVMNLDTVQDLFDASFSYRLVGACGL 195 Query: 210 ALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREM 269 +A G A+ WD+AA + + G +D + S + Sbjct: 196 DSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKAC 255 Query: 270 AMLIAQALQT 279 + + L Sbjct: 256 HETVLKILNA 265 >2WEF-A nrPDB Length = 311 Score = 182 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 72/271 (26%), Positives = 99/271 (36%), Gaps = 52/271 (19%) Query: 22 AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 +A +A +AG I+R+ + E + + KT A DL T+ D L + I S L +FP I Sbjct: 10 SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 69 Query: 81 EEAAAS-----------------GAKCVLTHSP-------TWIIDPIDGTCNFVHR-FPT 115 EE S C +S W+ DP+DGT + Sbjct: 70 EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTEGLLDN 128 Query: 116 VAVSIGFAVRQELEFGVIYHCTEE----------RLYTGRRGRGAFCNGQRLRVSGETDL 165 V V IG A + GVI R G G GAF G +L+ E Sbjct: 129 VTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLK---EVPA 183 Query: 166 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 225 K ++ T T + N + +L G ++I L G A AY Sbjct: 184 GKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKII--------QLIEGKASAYVFA 235 Query: 226 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 254 C WD A VI+ GG + D G L Sbjct: 236 SPGCKKWDTCAPEVILHAVGGKLTDIHGNVL 266 >4QXD-A nrPDB Length = 293 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 56/258 (21%), Positives = 98/258 (37%), Gaps = 45/258 (17%) Query: 21 QAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 + A I K EE + K+ ++ VT+ D + +I S ++ ++P+ I Sbjct: 10 NVLITAVKEASYSISK-FKEEVEIKYKSDGSE-VTQVDTQSQQIIFSIIKNKYPTINIIG 67 Query: 81 EEAAASGAKCVLTHSPTWI------------------IDPIDGTCNFVH-RFPTVAVSIG 121 EE +G + T + +DP+DGT + H ++ +V V +G Sbjct: 68 EEDVENGIPDNQLPTITQLSFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCVLVG 127 Query: 122 FAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPA 181 + + G++ F N + + + E +S + P D Sbjct: 128 VTYKGKPMIGIVSKP--------------FYNNE-ITFAIENYISS----ISLQPLNDKI 168 Query: 182 TLKLFLSN-MERLLHA--KAHGVRVIGSSTLALCHLASGAADAYYQFGLHC--WDLAAAT 236 N ++ L+ + + V+ G S + + AD YY + WD AA Sbjct: 169 IFVCSKKNDIQHLIKSFPDPYEVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQ 228 Query: 237 VIIREAGGIVIDTSGGPL 254 VI+ GGIV D G PL Sbjct: 229 VILEAQGGIVCDIYGNPL 246 >2Q74-A nrPDB Length = 299 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 85/255 (33%), Positives = 114/255 (44%), Gaps = 14/255 (5%) Query: 34 IRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAA-ASGAKCVL 92 I +A + V K+S D VT D E L+ L + P + EE + Sbjct: 36 ISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATP 95 Query: 93 THSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFC 152 + TW++DPIDGT NFV+ P AVSIG V G + +Y+ G GA Sbjct: 96 SDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHL 155 Query: 153 NGQR----LRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKA--HGVRVIGS 206 +R LR +G +LS AL+ T G ++ E L H VR IGS Sbjct: 156 TDERGRHVLRCTGVDELSMALLGTGFGYS-----VRCREKQAELLAHVVPLVRDVRRIGS 210 Query: 207 STLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAAST 266 + L LC +A+G DAYY+ G+ WD AA +I EAG V P A VV A+ Sbjct: 211 AALDLCMVAAGRLDAYYEHGVQVWDCAAGALIAAEAGARV--LLSTPRAGGAGLVVVAAA 268 Query: 267 REMAMLIAQALQTIN 281 +A + ALQ N Sbjct: 269 PGIADELLAALQRFN 283 >3B8B-A nrPDB Length = 292 Score = 167 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 61/227 (26%), Positives = 92/227 (40%), Gaps = 19/227 (8%) Query: 22 AAVQLALRAGQIIRKALTEEKRVSTKTSAAD--LVTETDHLVEDLIISELRER-FPSHRF 78 AA+ AL+AG+ I + K AD +T D + I++ L E FP Sbjct: 26 AAIDAALKAGEKILSIYEDPKSDFEIERKADNSPLTIADRKAHEAIVAILNETPFP---V 82 Query: 79 IAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTE 138 ++EE WI+DP+DGT F+ R V+I GVIY + Sbjct: 83 LSEEGKHMDYAVRRGWDTLWIVDPLDGTKEFIKRNGEFTVNIALVQNAVPVMGVIYVPVK 142 Query: 139 ERLYTGRRGRGAF-CNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERL---- 193 + LY G GA+ C+G L + + +E P D + +++ L Sbjct: 143 KELYFAVEGTGAYKCSGIVGLEDEGVTLQQMIEKSERMPLADARDHFIAVASRSHLTPET 202 Query: 194 ------LHAKAHGVRVIGS-STLALCHLASGAADAYYQFGLHC-WDL 232 L K V +I S S++ +C +A G AD Y +F WD Sbjct: 203 ETYIADLKKKHGNVELISSGSSIKICLVAEGKADVYPRFAPTMEWDT 249 >1KA0-A nrPDB Length = 357 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 68/348 (19%), Positives = 107/348 (30%), Gaps = 104/348 (29%) Query: 22 AAVQLALRAGQIIRKALTEE----KRVSTKTSAADLVTETDHLVEDLIISELRERFPSHR 77 A Q +A + ++ +E + + VT D+ + +II+ ++ FP + Sbjct: 9 VATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDK 68 Query: 78 FIAEEAAA--------------------------------------------------SG 87 + EE+++ G Sbjct: 69 VVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFG 128 Query: 88 AKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHC----------- 136 W +DPIDGT F+ AV + V ++ G I Sbjct: 129 NYEGGRKGRFWCLDPIDGTKGFLRG-EQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQD 187 Query: 137 -----TEERLYTGRRGRGAFCNGQ-------RLRVSGETDLSKALVLTEIG---PKRDPA 181 + ++ RG GAF + ++ V D + L + D Sbjct: 188 LKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQ 247 Query: 182 TLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLH------CWDLAAA 235 T N+ + LH S C LA G AD Y + + WD AA Sbjct: 248 TAIKNKLNISKSLHLD---------SQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAG 298 Query: 236 TVIIREAGGIVIDT-SGGPLDLMACRVVAA-------STREMAMLIAQ 275 VI+ EAGGI D PLD R +A RE+ L+ Sbjct: 299 NVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLVVS 346 >1LBZ-A nrPDB Length = 252 Score = 157 bits (397), Expect = 5e-39, Method: Composition-based stats. Identities = 59/275 (21%), Positives = 105/275 (38%), Gaps = 43/275 (15%) Query: 21 QAAVQLALR-AGQIIRKALTEEKRVSTK----TSAADLVTETDHLVEDLIISELRERFPS 75 + A++++ AG++ + + R K D + ED + LR+ Sbjct: 4 RDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKER-- 61 Query: 76 HRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELE---FGV 132 + EE+ G V +DP+DGT N P +VS+ F+ +L+ FG Sbjct: 62 VTVVTEESGVLGEGDVFVA-----LDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGY 116 Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192 +Y+ Y GA+ NG+R+ VS +L ++ P R Sbjct: 117 VYNLATGDEYYA-DSSGAYRNGERIEVSDAEELYCNAIIYY--PDRK------------- 160 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGL----HCWDLAAATVIIREAGGIVID 248 +R+ GS+ LC A G+ D + +D AA I +AGG V + Sbjct: 161 ---FPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTE 217 Query: 249 TSGGPL-----DLMACRVVAASTREMAMLIAQALQ 278 G L D+ + A+ ++ + + ++ Sbjct: 218 LDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 252 >5ESY-A nrPDB Length = 346 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 61/329 (18%), Positives = 108/329 (32%), Gaps = 66/329 (20%) Query: 8 QAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETD-----HLVE 62 +A L + + ++ V +A Q + + LV E D Sbjct: 26 KALLQSDVQSKSDKSPVTVADYGSQAVVSL---VLEKELSSEPFSLVAEEDSGDLRKDGS 82 Query: 63 DLIISELRERFPSHRFIAEEA--------------AASGAKCVLTHSPTWIIDPIDGTCN 108 + + + + EE+ G + W++DPIDGT Sbjct: 83 QDTLERITKL-VNDTLATEESFNGSTLSTDDLLRAIDCGTSEGGPNGRHWVLDPIDGTKG 141 Query: 109 FVHRFPTVAVSIGFAVRQELEFGVIYHCTEER------------------LYTGRRGRGA 150 F+ AV++G ++ GV+ L+ G G Sbjct: 142 FLRG-DQYAVALGLLEEGKVVLGVLACPNLPLASIAGNNKNKSSSDEIGCLFFATIGSGT 200 Query: 151 FC-------NGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRV 203 + + +++VS + +A L S++ L KA VR+ Sbjct: 201 YMQLLDSKSSPVKVQVSSVENPEEASFFESFEGAHSLHDLS---SSIANKLGVKAPPVRI 257 Query: 204 IGSSTLALCHLASGAADAYYQF-----GLHCWDLAAATVIIREAGGIVIDTSGGPLDLMA 258 S L+ G Y +F WD A +++ EAGGIV D +G PLD Sbjct: 258 --DSQAKYGALSRGDGAIYLRFPHKGYREKIWDHVAGAIVVTEAGGIVTDAAGKPLDFSK 315 Query: 259 CR-------VVAASTREMAMLIAQALQTI 280 + ++ A+ + M +L+ +I Sbjct: 316 GKYLDLDTGIIVANEKLMPLLLKAVRDSI 344 >5DJK-A nrPDB Length = 288 Score = 80.9 bits (198), Expect = 5e-16, Method: Composition-based stats. Identities = 47/213 (22%), Positives = 67/213 (31%), Gaps = 33/213 (15%) Query: 56 ETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNF-VHRFP 114 D L++ L+ P ++EE A L WIIDP+DGT F Sbjct: 69 AGDRQANSLLLRRLQAERPGDAVLSEE--AHDDLARLKSDRVWIIDPLDGTREFSTPGRD 126 Query: 115 TVAVSIGF---AVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVL 171 AV I + + + A G V Sbjct: 127 DWAVHIALWRRSSNGQP-----------EITDAAVALPA---------RGNVVYRTDTVT 166 Query: 172 TEIGPKRDPATLKLFLS--NMERLLHAKAHGVRV----IGSSTLALCHLASGAADAYYQF 225 + P P TL++ +S +LH + + IGS+ + G DAY Sbjct: 167 SGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHA 226 Query: 226 GLH-CWDLAAATVIIREAGGIVIDTSGGPLDLM 257 G WD AA ++ AG G PL Sbjct: 227 GGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYN 259 >1INP-A nrPDB Length = 400 Score = 64.4 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 58/195 (29%), Gaps = 35/195 (17%) Query: 90 CVLTHSPTWIIDPIDGTCNFVHR----------FPT----VAVSIGFA--VRQELEFGVI 133 W+ DPID T ++ FP+ V V IG GVI Sbjct: 143 IPQDILGIWV-DPIDSTYQYIKGSADITPNQGIFPSGLQCVTVLIGVYDIQTGVPLMGVI 201 Query: 134 YHC-----TEERLYTGRRGRGAFCNGQRLR-----VSGETDLSKALVLTEIGPKRDPATL 183 R + G+ G G + VS ++ T+ Sbjct: 202 NQPFVSQDLHTRRWKGQCYWGLSYLGTNIHSLLPPVSTRSNSEAQSQGTQNPSSEGSCRF 261 Query: 184 KLFLSNMER------LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHC--WDLAAA 235 + +S E+ L H + + + G AD Y WD AA Sbjct: 262 SVVISTSEKETIKGALSHVCGERIFRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAA 321 Query: 236 TVIIREAGGIVIDTS 250 I+R GG ++D Sbjct: 322 HAILRAMGGGMVDLK 336 >2F3D-A nrPDB Length = 338 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 51 ADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLT-HSPTWIIDPIDGTCN 108 D V + D L DL+I+ L+ F + ++EE + DP+DG+ N Sbjct: 68 GDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSN 126 >2FHY-A nrPDB Length = 374 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 51 ADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLT-HSPTWIIDPIDGTCN 108 D V + D L DL+++ L+ F + ++EE + DP+DG+ N Sbjct: 104 GDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSN 162 >1BK4-A nrPDB Length = 337 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 51 ADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLT-HSPTWIIDPIDGTCN 108 D V + D L DL+++ L+ F + ++EE + DP+DG+ N Sbjct: 67 GDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSN 125 >5Q0C-A nrPDB Length = 339 Score = 35.9 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 25/59 (42%), Gaps = 1/59 (1%) Query: 51 ADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLT-HSPTWIIDPIDGTCN 108 D V + D L L+I+ L+ + + ++EE + DP+DG+ N Sbjct: 68 GDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSN 126 >2QVR-A nrPDB Length = 332 Score = 34.3 bits (77), Expect = 0.054, Method: Composition-based stats. Identities = 39/247 (15%), Positives = 68/247 (27%), Gaps = 52/247 (21%) Query: 81 EEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAV---------------- 124 EE + ++DP+DG+ N V VS+G Sbjct: 90 EEDEIVVFEGCEHAKYVVLMDPLDGSSNI-----DVNVSVGTIFSIYRRVTPVGTPVTEE 144 Query: 125 ------RQELEFG-VIYHCTEERLYTGRRGRGAF----------CNGQRLRVSGETDLSK 167 +++ G V+Y + +YT G AF +R+R + Sbjct: 145 DFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYS 204 Query: 168 ALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCH-LASGAADAYYQFG 226 I F ++ + + R IGS L G Y Sbjct: 205 INEGNYIKFPNGVKKYIKFCQEEDKST-NRPYTSRYIGSLVADFHRNLLKGGIYLYPSTA 263 Query: 227 LHC-------WDLAAATVIIREAGGIVIDTSGGPLDLM-----ACRVVAASTREMAMLIA 274 H ++ + +AGG D LD++ R M + Sbjct: 264 SHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVE 323 Query: 275 QALQTIN 281 + ++ Sbjct: 324 RFIREFP 330 >5FGU-A nrPDB Length = 567 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 19/166 (11%), Positives = 55/166 (33%), Gaps = 4/166 (2%) Query: 122 FAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPA 181 + G ++ + L G F N + + ++ + + Sbjct: 349 LLSNGNVRNGYLFDRSG--LIADSLGGRPFRNN-LITGTRTQNVGNNDRKGGMQYIENKV 405 Query: 182 TLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIRE 241 + N + ++ KA V +++ ++D + + ++ A I + Sbjct: 406 LDHI-KRNPKVHVYYKATPVYQGSELLPRAVLVSALSSDGFIDETVRVFNNVAGFNIDYQ 464 Query: 242 AGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287 GG++ T+ ++ + + + E+ I T +D++ Sbjct: 465 NGGLLSSTADVDINNVEENEIETTDDEIEEGIENEPDTDALKKDNK 510 >1SPI-A nrPDB Length = 358 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 43/310 (13%), Positives = 84/310 (27%), Gaps = 59/310 (19%) Query: 11 LAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDL------ 64 L P A + + L + + K + + + ++ + + ED Sbjct: 27 LLKQPMAGVIDAELTIVLSSISLACKQIASLVQRAGISNLTGIQGAVNIQGEDQKKLDVV 86 Query: 65 ---IISELRERFPSHRFIA--EEAAASGAKCVLTHSPTWIIDPIDGTCN---FVHRFPTV 116 + S IA EE + + + + DP+DG+ N V Sbjct: 87 SNEVFSSCLRSSGRTGIIASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIF 146 Query: 117 AV--------------------------SIGFAVRQELEFGVIYH-CTEERLYTGRRGRG 149 + + + Y + ++ G+G Sbjct: 147 GIYSPNDECIVDSDHDDESQLSAEEQRCVVNVCQPGDNLLAAGYCMYSSSVIFVLTIGKG 206 Query: 150 AF------CNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLL----HAKAH 199 + G+ + S + + KA + M+ L K + Sbjct: 207 VYAFTLDPMYGEFVLTSEKIQIPKAGKIYSFNEGNYKMWPDKLKKYMDDLKEPGESQKPY 266 Query: 200 GVRVIGSSTLALCH-LASGAADAYYQFGLH-------CWDLAAATVIIREAGGIVIDTSG 251 R IGS L G Y + ++ A + I+ +AGG D Sbjct: 267 SSRYIGSLVGDFHRTLLYGGIYGYPRDAKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQ 326 Query: 252 GPLDLMACRV 261 LD+ + Sbjct: 327 RILDIQPTEI 336 >1DCU-A nrPDB Length = 357 Score = 32.4 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 31/230 (13%), Positives = 60/230 (26%), Gaps = 49/230 (21%) Query: 81 EEAAASGAKCVLTHSPTWIIDPIDGTCNF--------VHRF--------PTVA------- 117 EE + + + + DP+DG+ N + P Sbjct: 106 EEDVPVAVEESYSGNYIVVFDPLDGSSNLDAAVSTGSIFGIYSPNDECLPDFGDDSDDNT 165 Query: 118 -------VSIGFAVRQELEFGVIYH-CTEERLYTGRRGRGAF------CNGQRLRVSGET 163 + Y + ++ G+G F G+ + Sbjct: 166 LGTEEQRCIVNVCQPGSNLLAAGYCMYSSSVIFVLTIGKGVFVFTLDPLYGEFVLTQENL 225 Query: 164 DLSKALVLTEIGPKRDPATLKLFLSNMERLL----HAKAHGVRVIGSSTLALCH-LASGA 218 + K+ + + ++ L K + R IGS L G Sbjct: 226 QIPKSGKIYSFNEGNYKLWDENLKKYIDDLKEPGPSGKPYSARYIGSLVGDFHRTLLYGG 285 Query: 219 ADAYYQFGLH-------CWDLAAATVIIREAGGIVIDTSGGPLDLMACRV 261 Y + ++ A + I+ +AGG D LD+ + Sbjct: 286 IYGYPRDKKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRVLDIQPTEI 335 >5IZ1-A nrPDB Length = 337 Score = 32.0 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 34/93 (36%), Gaps = 9/93 (9%) Query: 18 ECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHR 77 C Q A L RAG L + + + D + ++ S LR + Sbjct: 31 ACKQIA-SLVQRAGISNLTGLQGVANIQ-----GEDQKKLDVISNEVFSSCLRSSGRT-G 83 Query: 78 FIA--EEAAASGAKCVLTHSPTWIIDPIDGTCN 108 IA EE + + + + DP+DG+ N Sbjct: 84 IIASEEEDTPVAVEESYSGNYIVVFDPLDGSSN 116 >6N9G-C nrPDB Length = 353 Score = 32.0 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 15/125 (12%), Positives = 36/125 (28%), Gaps = 3/125 (2%) Query: 111 HRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALV 170 H + + + + C ++ + R G S + Sbjct: 194 HGADVLCLDLAPSETGNTFVS--GGCDKKAMVWDMR-SGQCVQAFETHESDVNSVRYYPS 250 Query: 171 LTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCW 230 D AT +L+ +R + + + G+S++ Y + ++ W Sbjct: 251 GDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVW 310 Query: 231 DLAAA 235 D+ Sbjct: 311 DVLKG 315 >4JG5-A nrPDB Length = 355 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 34/189 (17%), Positives = 55/189 (29%), Gaps = 19/189 (10%) Query: 4 SGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVED 63 SG + +A+ A A+RA I+ + + + T D + Sbjct: 67 SGAEHSAIIAD-------VPTTKAVRARIIVLANVPRDLLSTVSTYDEFQTRLVDLSSQS 119 Query: 64 LIISELR-ERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGF 122 + + + ++EE G + + I DPI T R V +S F Sbjct: 120 QTNLTMSSQVIVTKSALSEEDNYLGYTDLGDQNVDGISDPILLTR-VAARIDLVNISTRF 178 Query: 123 AVRQELEFGV--------IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEI 174 A G IY+ + Y G +R S +T LV Sbjct: 179 A--GTPFAGREVRIDAVGIYNMKTKSYYFSEADWGETEAPDAVRNSEDTSFEDLLVNDGT 236 Query: 175 GPKRDPATL 183 P Sbjct: 237 SISNTPFVH 245 >3CMG-A nrPDB Length = 667 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 14/42 (33%), Gaps = 1/42 (2%) Query: 116 VAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRL 157 VSI + V R Y +G F NG+ L Sbjct: 243 YQVSISLHKDGKQIDSVT-QPLGLRYYHTDPDKGFFLNGKHL 283 >6HHQ-h nrPDB Length = 319 Score = 28.9 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 29/94 (30%), Gaps = 3/94 (3%) Query: 174 IGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGA--ADAYYQFGLHCWD 231 + RD + L+ ++ + A GA A + L WD Sbjct: 34 LSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWD 93 Query: 232 LAAATVIIREAGGIVIDTSGGPLDLMACRVVAAS 265 +A R G D +D A +++ S Sbjct: 94 VATGETYQRFVGHK-SDVMSVDIDKKASMIISGS 126 >4ZSG-A nrPDB Length = 347 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 20/46 (43%), Gaps = 3/46 (6%) Query: 35 RKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 R+ ++ + +A D+VT + +L ++ + F IA Sbjct: 28 RRLTGQQVAIKKIPNAFDVVTNAKRTLREL---KILKHFKHDNIIA 70 >4IC8-A nrPDB Length = 442 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 20/46 (43%), Gaps = 3/46 (6%) Query: 35 RKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80 R+ ++ + +A D+VT + +L ++ + F IA Sbjct: 76 RRLTGQQVAIKKIPNAFDVVTNAKRTLREL---KILKHFKHDNIIA 118 >5EUA-A nrPDB Length = 265 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 21/56 (37%) Query: 189 NMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGG 244 N ER LH + + + Q L D AAA ++++E GG Sbjct: 64 NPERKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSALQLSDNAAANLLLKEVGG 119 >4MKS-A nrPDB Length = 440 Score = 28.2 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 36/133 (27%), Gaps = 31/133 (23%) Query: 14 GPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERF 73 P+E +A + + GQ I A VT D Sbjct: 217 EPFEILVEAIQRAGYKPGQDIAIAFDCAASEFYNKDTKKYVTVAD--------------- 261 Query: 74 PSHRFIAEEAAASGAKCVLTHSPTWIIDPID-----GTCNFVHRF---------PTVAVS 119 + AEE + V + + DP+D G F R + Sbjct: 262 -GREYTAEEWTSLIEDLVDKYPVISVEDPLDENDWEGWKTFTERLGDKVQIVGDDLFVTN 320 Query: 120 IGFAVRQELEFGV 132 + + ++ GV Sbjct: 321 TSYLEKG-IKMGV 332 >5OQL-J nrPDB Length = 912 Score = 28.2 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 43/165 (26%), Gaps = 33/165 (20%) Query: 85 ASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHC-TEERLYT 143 A+ T +I PI + S+ + + L T Sbjct: 2 ATKQPAKTTFEVANVIQPI-----YTGG------SVALENGARILASTLGENAILTELNT 50 Query: 144 GRRGRGAFCNGQRLRVSGETDLSKALVLTEIG-----------PKRDPATLKLFLSNMER 192 G+R +G+ + T L++ P D L + Sbjct: 51 GKRLAEIQGDGEPISTLTITPSGSHLIVCSRSLTMRIYSLAISPDYDSVEPTLVRTTKPH 110 Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATV 237 V + LA+GAAD + WD+ V Sbjct: 111 ATPVVVLAVDRTST------LLATGAADG----AIKIWDIIGGYV 145 >3FN9-A nrPDB Length = 692 Score = 28.2 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 15/41 (36%), Gaps = 1/41 (2%) Query: 116 VAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQR 156 V ++ V+ R Y G+G F NG++ Sbjct: 257 YKVVCRLMADGKVIDEVV-QPLGVRKYEIVAGKGFFLNGEK 296 >4LJ8-A nrPDB Length = 339 Score = 27.8 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 16/41 (39%) Query: 244 GIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGR 284 G + D+ G +D ++ S +++ + Y R Sbjct: 172 GRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQKGWPYER 212 >3BRN-A nrPDB Length = 157 Score = 27.8 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 22/66 (33%) Query: 153 NGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALC 212 NG ++ V+G R ++ N E +H+ A ++ G Sbjct: 78 NGDKIEVTGAGQDLSGTTTVLFSDYRSCDVMRGPDGNYELWVHSSAINLQSYGCCDTKFA 137 Query: 213 HLASGA 218 +A G Sbjct: 138 QVAGGR 143 >1QVR-A nrPDB Length = 854 Score = 27.8 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 16/41 (39%) Query: 244 GIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGR 284 G + D+ G +D ++ S +++ + Y R Sbjct: 687 GRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQKGWPYER 727 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.130 0.346 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,779,773 Number of Sequences: 36641 Number of extensions: 348497 Number of successful extensions: 1163 Number of sequences better than 10.0: 51 Number of HSP's better than 10.0 without gapping: 62 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 985 Number of HSP's gapped (non-prelim): 91 length of query: 288 length of database: 10,336,785 effective HSP length: 96 effective length of query: 192 effective length of database: 6,819,249 effective search space: 1309295808 effective search space used: 1309295808 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.0 bits)