BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O08967 (399 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6BBQ-A nrPDB 707 0.0 2R09-A nrPDB 702 0.0 4JWL-A nrPDB 362 e-100 4A4P-A nrPDB 352 1e-97 3LTL-A nrPDB 196 1e-50 3SWV-A nrPDB 192 2e-49 4OIY-A nrPDB 168 3e-42 5NLY-A nrPDB 159 2e-39 6FAE-A nrPDB 147 1e-35 4C7P-A nrPDB 127 9e-30 1XSZ-A nrPDB 127 1e-29 1XT0-B nrPDB 123 1e-28 4D7Q-A nrPDB 122 2e-28 4D7R-A nrPDB 116 2e-26 1RE0-B nrPDB 111 5e-25 1KU1-A nrPDB 108 6e-24 5KCV-A nrPDB 45 7e-05 1V5U-A nrPDB 44 1e-04 2UVM-A nrPDB 43 2e-04 5A3F-A nrPDB 42 6e-04 4GZU-A nrPDB 42 6e-04 4H6Y-A nrPDB 42 6e-04 2X18-A nrPDB 39 0.003 2YS1-A nrPDB 39 0.005 6DLV-b nrPDB 38 0.010 2DTC-A nrPDB 37 0.014 1DYN-A nrPDB 37 0.019 4UUD-B nrPDB 36 0.025 3VIA-A nrPDB 36 0.026 2DHI-A nrPDB 35 0.039 2LUL-A nrPDB 35 0.039 2D9V-A nrPDB 35 0.073 2D9Z-A nrPDB 33 0.21 6E31-A nrPDB 33 0.25 3TCA-A nrPDB 32 0.45 2COA-A nrPDB 31 1.1 4A6K-A nrPDB 31 1.2 5JPQ-o nrPDB 30 1.3 3FM8-C nrPDB 30 1.9 1WI1-A nrPDB 28 4.8 4GN1-A nrPDB 28 5.6 >6BBQ-A nrPDB Length = 520 Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/341 (98%), Positives = 337/341 (98%) Query: 59 EESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 118 TTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD Sbjct: 7 HHGSTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 66 Query: 119 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 178 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL Sbjct: 67 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 126 Query: 179 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 238 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN Sbjct: 127 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 186 Query: 239 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 298 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY Sbjct: 187 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 246 Query: 299 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 358 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY Sbjct: 247 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 306 Query: 359 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 399 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK Sbjct: 307 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 347 >2R09-A nrPDB Length = 347 Score = 702 bits (1812), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/341 (98%), Positives = 336/341 (98%) Query: 59 EESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 118 TTQRN QIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD Sbjct: 7 HHGSTTQRNAQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 66 Query: 119 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 178 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL Sbjct: 67 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 126 Query: 179 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 238 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN Sbjct: 127 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 186 Query: 239 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 298 LYESIKNEPFKIPEDDGNDLT+TFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY Sbjct: 187 LYESIKNEPFKIPEDDGNDLTYTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 246 Query: 299 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 358 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY Sbjct: 247 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 306 Query: 359 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 399 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK Sbjct: 307 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 347 >4JWL-A nrPDB Length = 217 Score = 362 bits (929), Expect = e-100, Method: Compositional matrix adjust. Identities = 167/196 (85%), Positives = 185/196 (94%) Query: 61 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL 120 SKT QRN+++AMGRKKFNMDPKKGIQFL+EN+LLQ++PE++A+FLYKGEGLNKT IGDYL Sbjct: 22 SKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYL 81 Query: 121 GERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN 180 GER++ N+ VL AFV+LHEF DLNLVQALRQFLWSFRLPGEAQKIDRMMEAFA RYCLCN Sbjct: 82 GEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCN 141 Query: 181 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLY 240 PGVFQSTDTCYVLSFA+IMLNTSLHN NVRDKP ERF+ MNRGINEGGDLPEELLRNLY Sbjct: 142 PGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLY 201 Query: 241 ESIKNEPFKIPEDDGN 256 +SI+NEPFKIPEDDGN Sbjct: 202 DSIRNEPFKIPEDDGN 217 >4A4P-A nrPDB Length = 192 Score = 352 bits (904), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 167/186 (89%), Positives = 176/186 (94%) Query: 67 NKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDF 126 NKQ+AMGRKKFNMDPKKGIQFLIENDLL+++ ED+AQFLYKGEGLNKT IGDYLGERD+F Sbjct: 7 NKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEF 66 Query: 127 NIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQS 186 NI+VL AFVELHEF DLNLVQALRQFLWSFRLPGEAQKIDRMMEAFA RYC CN GVFQS Sbjct: 67 NIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQS 126 Query: 187 TDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNE 246 TDTCYVLSFAIIMLNTSLHN NV+DKPT ERFI MNRGIN+GGDLPEELLRNLYESIKNE Sbjct: 127 TDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNE 186 Query: 247 PFKIPE 252 PFKIPE Sbjct: 187 PFKIPE 192 >3LTL-A nrPDB Length = 211 Score = 196 bits (499), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 95/190 (50%), Positives = 132/190 (69%), Gaps = 2/190 (1%) Query: 65 QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERD 124 Q+ + I G FN PK+GIQ+L E +L ++PED+AQFL++ E L+ T +G++LG+ D Sbjct: 17 QQKEIIEQGIDLFNKKPKRGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDND 76 Query: 125 DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPG-- 182 FN +V+ A+V+ H+F+ + V ALR FL FRLPGEAQKIDR+ME FA+RY CN G Sbjct: 77 KFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQT 136 Query: 183 VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYES 242 +F S DT YVL+++IIML T LH+ V++K T E++I MNRGIN+ DLPEE L +Y Sbjct: 137 LFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNE 196 Query: 243 IKNEPFKIPE 252 I + + E Sbjct: 197 IAGKKISMKE 206 >3SWV-A nrPDB Length = 202 Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 96/190 (50%), Positives = 132/190 (69%), Gaps = 2/190 (1%) Query: 65 QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERD 124 Q+ + I G + FN PK+GIQFL E +L +S ED+AQFL++ E L+ T +GD+LG+ Sbjct: 8 QQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSA 67 Query: 125 DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPG-- 182 FN +V+ A+V+ +F + V ALR FL FRLPGEAQKIDR+ME FA+RY CN G Sbjct: 68 RFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQT 127 Query: 183 VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYES 242 +F S DT YVL+++IIML T LH+ V++K T E++I MNRGIN+ DLPEE L ++YE Sbjct: 128 LFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEE 187 Query: 243 IKNEPFKIPE 252 I+ + + E Sbjct: 188 IEGKKIAMKE 197 >4OIY-A nrPDB Length = 191 Score = 168 bits (426), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 83/170 (48%), Positives = 112/170 (65%), Gaps = 1/170 (0%) Query: 77 FNMDPKKGIQFLIENDLLQS-SPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFV 135 FN PKK I LI+ L+ SP +A++L + EGL+ +GDYLGE DD NI ++ AFV Sbjct: 19 FNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFV 78 Query: 136 ELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSF 195 + +F +++V ALR FL SFRLPGE QKIDR M FA R+ NPGVF DT YVLS+ Sbjct: 79 DEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSY 138 Query: 196 AIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKN 245 ++IMLNT LH+ +++K + + F+ N GI+ G DLP + L L+ I N Sbjct: 139 SLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIAN 188 >5NLY-A nrPDB Length = 405 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 83/199 (41%), Positives = 127/199 (63%), Gaps = 6/199 (3%) Query: 61 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL 120 S R + +G FN P+KG+Q+LIE + +P VA FL + +GL++ +IG++L Sbjct: 39 SNDVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFL 98 Query: 121 GERD-DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLC 179 G R FN VL V+ +F+ + L +ALR+F R+ GEAQK++R++EAF+ RYC+C Sbjct: 99 GNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCIC 158 Query: 180 NPGV---FQSTDTCYVLSFAIIMLNTSLHNHNVRD--KPTAERFITMNRGINEGGDLPEE 234 NPGV F++ DT ++L+FAII+LNT +++ NV+ K E FI RG+++G D+P E Sbjct: 159 NPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPRE 218 Query: 235 LLRNLYESIKNEPFKIPED 253 +L +YE I+ K ED Sbjct: 219 MLMGIYERIRKRELKTNED 237 >6FAE-A nrPDB Length = 371 Score = 147 bits (370), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 75/188 (39%), Positives = 122/188 (64%), Gaps = 6/188 (3%) Query: 72 MGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERD-DFNIKV 130 +G FN P+KGIQ+LIE L +P VA F+ + +GL++ +IG++LG R FN V Sbjct: 31 IGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDV 90 Query: 131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGV---FQST 187 L V+ +F+ ++L ALR+F R+ GEAQK++R++EAF+ RYC+CNP + F++ Sbjct: 91 LDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNP 150 Query: 188 DTCYVLSFAIIMLNTSLHNHNVRD--KPTAERFITMNRGINEGGDLPEELLRNLYESIKN 245 DT ++L+FAII+LNT +++ +V+ K + FI RG++ G D+P +LL +Y+ I+ Sbjct: 151 DTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQG 210 Query: 246 EPFKIPED 253 + +D Sbjct: 211 RELRTNDD 218 >4C7P-A nrPDB Length = 402 Score = 127 bits (319), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 77/198 (38%), Positives = 113/198 (57%), Gaps = 8/198 (4%) Query: 77 FNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKVLQA 133 FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +VL+A Sbjct: 44 FNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKA 103 Query: 134 FVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVL 193 F F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Y+L Sbjct: 104 FTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLL 163 Query: 194 SFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFK-- 249 +F IMLNT LHN ++ ++K T + RG N GGD + L LY IK +PF+ Sbjct: 164 AFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFELN 223 Query: 250 -IPEDDGNDLTHTFFNPD 266 + G +LT T N D Sbjct: 224 FVKTSPGYELTSTTLNKD 241 >1XSZ-A nrPDB Length = 356 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 77/198 (38%), Positives = 113/198 (57%), Gaps = 8/198 (4%) Query: 77 FNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKVLQA 133 FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +VL+A Sbjct: 18 FNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKA 77 Query: 134 FVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVL 193 F F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Y+L Sbjct: 78 FTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLL 137 Query: 194 SFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFK-- 249 +F IMLNT LHN ++ ++K T + RG N GGD + L LY IK +PF+ Sbjct: 138 AFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFELN 197 Query: 250 -IPEDDGNDLTHTFFNPD 266 + G +LT T N D Sbjct: 198 FVKTSPGYELTSTTLNKD 215 >1XT0-B nrPDB Length = 203 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 71/179 (39%), Positives = 106/179 (59%), Gaps = 5/179 (2%) Query: 77 FNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKVLQA 133 FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +VL+A Sbjct: 18 FNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKA 77 Query: 134 FVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVL 193 F F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Y+L Sbjct: 78 FTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLL 137 Query: 194 SFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKI 250 +F IMLNT LHN ++ ++K T + RG N GGD + L LY IK +PF++ Sbjct: 138 AFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFEL 196 >4D7Q-A nrPDB Length = 352 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 71/179 (39%), Positives = 105/179 (58%), Gaps = 5/179 (2%) Query: 77 FNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKVLQA 133 FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +VL+A Sbjct: 22 FNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKA 81 Query: 134 FVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVL 193 F F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Y+L Sbjct: 82 FTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLL 141 Query: 194 SFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKI 250 +F IMLNT LHN ++ ++K T RG N GGD + L LY IK +PF++ Sbjct: 142 AFQTIMLNTDLHNPSIPEKNKMTVYGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFEL 200 >4D7R-A nrPDB Length = 400 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 74/201 (36%), Positives = 113/201 (56%), Gaps = 9/201 (4%) Query: 75 KKFNMDPKKGIQFLIE--NDLLQSSPEDVAQFLYKGEG-LNKTVIGDYLGERDDFNIKVL 131 K FN PK GI + + D Q + A+ Y+ + LN +GDYLG N KVL Sbjct: 39 KLFNDKPKSGIARIKKWCTDNNQDFIAETAKIFYEEKSNLNLEFVGDYLGTDGVDNQKVL 98 Query: 132 QAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGV-FQSTDTC 190 ++F + +F + + +++LR+FL SF+LPGEAQKIDR++E+F + Y N + S D Sbjct: 99 ESFTKQFDFKEKDYLESLRRFLQSFKLPGEAQKIDRLVESFGTHYYEQNLNIDINSKDAA 158 Query: 191 YVLSFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPF 248 Y+L++ IMLNT LHN ++ K T E+ +G NE + + L+ +Y+ I+ +PF Sbjct: 159 YILAYQTIMLNTDLHNPSIAKSKKMTFEQLKNNLKGTNESKNFNDNFLKKIYDEIEAKPF 218 Query: 249 K---IPEDDGNDLTHTFFNPD 266 K + G +LT T N D Sbjct: 219 KLNFVKTSPGYELTSTTLNKD 239 >1RE0-B nrPDB Length = 221 Score = 111 bits (278), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 75/218 (34%), Positives = 108/218 (49%), Gaps = 29/218 (13%) Query: 63 TTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQS-SPEDVAQFLYKGEG-LNKTVIGDYL 120 + R + + + FN KKGIQ LIE + S S D+A FL+ G LNK IG L Sbjct: 5 ASDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLL 64 Query: 121 GERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN 180 D +L+ F++L +F L + +A+R L FRLPGE+Q+I+R++EAF+S+Y Sbjct: 65 C--DPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQ 122 Query: 181 PG-------------------------VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTA 215 V D+ +VLS++IIMLNT HN V+D T Sbjct: 123 SNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTF 182 Query: 216 ERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPED 253 + + RG G D P L +Y SIK + +PE+ Sbjct: 183 DDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEE 220 >1KU1-A nrPDB Length = 230 Score = 108 bits (269), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 69/194 (35%), Positives = 107/194 (55%), Gaps = 19/194 (9%) Query: 77 FNMDPKKGIQFLIENDLLQS-SPEDVAQFLYKGEG-LNKTVIGDYLGERDDFNIKVLQAF 134 FN PKKGI LIE + S S +D+A+FL+ +NK IG L D + +L + Sbjct: 34 FNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCHPD--KVSLLNEY 91 Query: 135 VELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL---CNPG--------- 182 + L +F+ L + +A+R L FRLPGE+Q+I+R++EAF+S YC +P Sbjct: 92 IRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCENQDYDPSKISDNAEDD 151 Query: 183 ---VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNL 239 V D+ ++LS++IIMLNT LHN V++ + E + +G D P L + Sbjct: 152 ISTVQPDADSVFILSYSIIMLNTDLHNPQVKEHMSFEDYSGNLKGCCNHKDFPFWYLDRV 211 Query: 240 YESIKNEPFKIPED 253 Y SI+++ +PE+ Sbjct: 212 YCSIRDKEIVMPEE 225 >5KCV-A nrPDB Length = 460 Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 29/119 (24%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLY--YFEYTTDKEPRGIIPLENLSIRE-----VE 319 +EGWL K G +KTW+ R+F+L ++ + Y E D + R PL N S+ + E Sbjct: 22 KEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRE-APLNNFSVAQCQLMKTE 80 Query: 320 DPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR-ISAPSPEEKEEWMKSIKA 377 PR PN F + R ++ V+ R +PEE+EEW +I+ Sbjct: 81 RPR-PNTFII-------------------RCLQWTTVIERTFHVETPEEREEWTTAIQT 119 >1V5U-A nrPDB Length = 117 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 20/120 (16%) Query: 268 EGWLLKLGGRVKTWKRRWFIL--TDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPN 325 EG L K G +K WK RWF+L T + L Y+++ D E +G+I L + E P P Sbjct: 11 EGILYKKGAFMKPWKARWFVLDKTKHQLRYYDHRMDTECKGVIDLAEV---EAVAPGTP- 66 Query: 326 CFELYNPSHKGQVIKACKTEADGRV--VEGNHVVYRISAPSPEEKEEWMKSIKASISRDP 383 I A KT + V+ VY A ++W+ I++ +S P Sbjct: 67 ------------TIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSSGP 114 >2UVM-A nrPDB Length = 123 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 29/119 (24%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLY--YFEYTTDKEPRGIIPLENLSIRE-----VE 319 +EGWL K G +KTW+ R+F+L ++ + Y E D + R PL N S+ + E Sbjct: 8 KEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRE-APLNNFSVAQCQLMKTE 66 Query: 320 DPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR-ISAPSPEEKEEWMKSIKA 377 PR PN F + R ++ V+ R +PEE+EEW +I+ Sbjct: 67 RPR-PNTFII-------------------RCLQWTTVIERTFHVETPEEREEWTTAIQT 105 >5A3F-A nrPDB Length = 754 Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 22/123 (17%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDP--R 322 R+GWL +G K WF+LT L +++ +KE + ++PL+NL +R+VE Sbjct: 518 RKGWLTISNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMS 577 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + F L+N + R V ++ ++ S E+ + W KAS+ R Sbjct: 578 SKHIFALFN--------------TEQRNVYKDYRFLELACDSQEDVDSW----KASLLRA 619 Query: 383 PFY 385 Y Sbjct: 620 GVY 622 >4GZU-A nrPDB Length = 501 Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 25/115 (21%) Query: 269 GWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSI---REVEDPRKPN 325 G+LL+ W++ W + T+ CL++++ D P +PL S+ RE + K Sbjct: 404 GYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDY 463 Query: 326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASIS 380 F+L SH VY A S E WM IK + S Sbjct: 464 VFKLQFKSH----------------------VYFFRAESKYTFERWMDVIKRASS 496 Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 27/117 (23%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP---RGIIPLENLSIREVEDPRK 323 REG L KL + +R +F+ +D LY + T RG +PL + + E E+ Sbjct: 230 REGCLHKLTKK-GLQQRMFFLFSDMLLYTSKSVTGASHFRIRGFLPLRGMLVEESENEWS 288 Query: 324 P-NCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379 +CF +Y A +V ++A + EKE+WM+ + A+I Sbjct: 289 VLHCFTIY--------------AAQKTIV--------VAASTRLEKEKWMQDLNAAI 323 >4H6Y-A nrPDB Length = 501 Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 25/115 (21%) Query: 269 GWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSI---REVEDPRKPN 325 G LL+ W++ W + T+ CL++++ D P +PL S+ E E+ +K Sbjct: 403 GNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDY 462 Query: 326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASIS 380 F+L+ SH VY A S E WM+ I+++ S Sbjct: 463 VFKLHFKSH----------------------VYYFRAESEYTFERWMEVIRSATS 495 >2X18-A nrPDB Length = 119 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 32/124 (25%) Query: 267 REGWLLKLGGRVKTWKRRWFIL-TDNCLYYFEYTTDKEPRGI---IPLENLSIREVE--- 319 +EGW+ K G +K W+ R+F+L TD ++ ++P+ + PL N S+ + + Sbjct: 9 KEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYK----EKPQDVDLPYPLNNFSVAKCQLMK 64 Query: 320 -DPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR-ISAPSPEEKEEWMKSIKA 377 + KPN F + R ++ V+ R +PEE+EEW ++I+A Sbjct: 65 TERPKPNTFII-------------------RCLQWTTVIERTFHVDTPEEREEWTEAIQA 105 Query: 378 SISR 381 R Sbjct: 106 VADR 109 >2YS1-A nrPDB Length = 113 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 18/95 (18%) Query: 267 REGWL------LKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED 320 R GWL L GG K WF+LT L +++ +KE + ++PL+NL IR+VE Sbjct: 10 RRGWLTINNISLMKGGS----KEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEK 65 Query: 321 PRKPN--CFELYNPSHKG------QVIKACKTEAD 347 N F ++N + Q+ AC ++ D Sbjct: 66 GFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQED 100 >6DLV-b nrPDB Length = 748 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 10/89 (11%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDP--R 322 R+GWL +G K WF+LT L +++ +KE + ++ ++NL +R+VE Sbjct: 522 RKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMS 581 Query: 323 KPNCFELYNPSHKG------QVIKACKTE 345 + F L+N + Q+ AC+T+ Sbjct: 582 SKHIFALFNTEQRNVYKDYRQLELACETQ 610 >2DTC-A nrPDB Length = 126 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 12/91 (13%) Query: 261 TFFNPDREGWLLKLGGR--VKTWKRRWFILTDNCLYYFEYT----TDKEPRGIIPLENLS 314 T P R LLK G + + +W R W +L+ L Y+ TD++ P + +S Sbjct: 2 TMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGATLLYYGAKSLRGTDRKHYKSTPGKKVS 61 Query: 315 I-----REVEDPRKPNCFELYNPSHKGQVIK 340 I + +DP P+ F+L NP KG V K Sbjct: 62 IVGWMVQLPDDPEHPDIFQLNNPD-KGNVYK 91 >1DYN-A nrPDB Length = 125 Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 10/89 (11%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDP--R 322 R+GWL +G K WF+LT L +++ +KE + ++ ++NL +R+VE Sbjct: 14 RKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMS 73 Query: 323 KPNCFELYNPSHKG------QVIKACKTE 345 + F L+N + Q+ AC+T+ Sbjct: 74 SKHIFALFNTEQRNVYKDYRQLELACETQ 102 >4UUD-B nrPDB Length = 864 Score = 36.2 bits (82), Expect = 0.025, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 10/89 (11%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDP--R 322 R+GWL +G K WF+LT L +++ +KE + ++ ++NL +R+VE Sbjct: 522 RKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMS 581 Query: 323 KPNCFELYNPSHKG------QVIKACKTE 345 + F L+N + Q+ AC+T+ Sbjct: 582 SKHIFALFNTEQRNVYKDYRQLELACETQ 610 >3VIA-A nrPDB Length = 112 Score = 36.2 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 6/65 (9%) Query: 267 REGWLLKLGGRVKTWKRRWFIL-TDNCLYYFEYTTDK--EPRGIIPLENLSIR---EVED 320 + GWLL+ +K WK+ WF L +D L Y++ T + E + +P++ ++IR E D Sbjct: 7 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRD 66 Query: 321 PRKPN 325 + P+ Sbjct: 67 TQPPD 71 >2DHI-A nrPDB Length = 120 Score = 35.4 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 10/91 (10%) Query: 267 REGWLLKLGGRVKTWKRRWFIL-TDNCLYYFEYTTDK--EPRGIIPLENLSIREVEDPR- 322 + GWLL+ +K WK+ WF L +D L Y++ T + E + +P++ ++IR + R Sbjct: 10 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIRTGHECRD 69 Query: 323 ------KPNCFELYNPSHKGQVIKACKTEAD 347 KP L G+ I C D Sbjct: 70 IQPPDGKPRDCLLQIVCRDGKTISLCAESTD 100 >2LUL-A nrPDB Length = 164 Score = 35.4 bits (80), Expect = 0.039, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 16/103 (15%) Query: 281 WKRRWFILTDNCLYYFEYTTDKEPR-GIIPLENLSIREVEDPRKPNCFELYNPSHKGQVI 339 +K R F+LT + L Y+E +K+ R G I D K C E+ + VI Sbjct: 36 YKERLFVLTKSMLTYYEGRAEKKYRKGFI-----------DVSKIKCVEIV--KNDDGVI 82 Query: 340 KACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 C+ + +VV + +Y I APSP+ ++ W+K +K I + Sbjct: 83 -PCQNKYPFQVVHDANTLY-IFAPSPQSRDLWVKKLKEEIKNN 123 >2D9V-A nrPDB Length = 130 Score = 34.7 bits (78), Expect = 0.073, Method: Composition-based stats. Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Query: 267 REGWLLKLGGRVKTWKRRWFIL-TDNCLYYF--EYTTDKEPRGIIPLENLSIR---EVED 320 R GWL + ++ WKR WF L D L Y+ E D+E R +I I+ E +D Sbjct: 10 RGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVIHFNVRDIKVGQECQD 69 Query: 321 PRKP 324 + P Sbjct: 70 VQPP 73 >2D9Z-A nrPDB Length = 129 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 11/72 (15%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPR---- 322 +EGW++ R KR ++ L CL F+ + + IPL I + PR Sbjct: 10 KEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLS--EILRISSPRDFTN 67 Query: 323 -----KPNCFEL 329 P+CFE+ Sbjct: 68 ISQGSNPHCFEI 79 >6E31-A nrPDB Length = 359 Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust. Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 5/55 (9%) Query: 265 PDREGWL-LKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGI---IPLENLSI 315 P+ EG L LK G+ K+WKRR+F+L + +YY K R + I EN++I Sbjct: 236 PELEGALYLKEDGK-KSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNI 289 >3TCA-A nrPDB Length = 291 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 5/55 (9%) Query: 265 PDREGWL-LKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGI---IPLENLSI 315 P+ EG L LK G+ K+WKRR+F+L + +YY K R + I EN++I Sbjct: 168 PELEGALYLKEDGK-KSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNI 221 >2COA-A nrPDB Length = 125 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPL-ENLSIREVED----- 320 REGW++ + KR ++ L C+ F+ T IPL E L++ ++ Sbjct: 10 REGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVP 69 Query: 321 -PRKPNCFEL 329 P+CFE+ Sbjct: 70 PGTNPHCFEI 79 >4A6K-A nrPDB Length = 120 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Query: 263 FNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPR 322 F + G+L + +K++ + +++LT N L+ E+ T + ++P+ +L++ E Sbjct: 4 FTEIKSGFLERRSKFLKSYSKGYYVLTPNFLH--EFKTADRKKDLVPVMSLALSECTVTE 61 Query: 323 KPNCFELYNPSHKGQVIK-ACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIK 376 +P+ G K + +G + G++ V++ A S E W ++K Sbjct: 62 HSRKNSTSSPNSTGSDAKFVLHAKQNGIIRRGHNWVFK--ADSYESMMSWFDNLK 114 >5JPQ-o nrPDB Length = 265 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 5/42 (11%) Query: 301 DKEPRGIIPLENLSIREVEDPRKP-----NCFELYNPSHKGQ 337 +KE + I PL+N++IR+V+ ++P ELY+ KG+ Sbjct: 204 EKETKNIFPLQNITIRKVKVLKRPKLDATKIAELYSHEKKGE 245 >3FM8-C nrPDB Length = 392 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Query: 267 REGWLLKLGGRVKTWKRRWFILTD--NCLYYFEYTTDKEPRGIIPLENLS 314 REG+L K G + R F+LT+ L YF KEP+ ++ +E+L+ Sbjct: 150 REGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLN 199 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 12/93 (12%) Query: 267 REGWLLKLGGR-VKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPL----ENLSIREVEDP 321 +EG++ K G + + +++RWF + D L YF+ D RG + + ++ P Sbjct: 273 KEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPP 332 Query: 322 RK-----PNCFELYNPSHKGQVIKACKTEADGR 349 P+ + P K + AC+TE+D R Sbjct: 333 STQGHHWPHGITIVTPDRK--FLFACETESDQR 363 >1WI1-A nrPDB Length = 126 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 6/59 (10%) Query: 269 GWLLKLGGRV-KTWKRRWFILTDNCLYYF---EYTTDK-EPRGIIPLENLSIREVEDPR 322 G+L +G V K WK+R+F+L Y F Y K EP+ ++ L+ ++ + DP+ Sbjct: 12 GYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTV-DYTDPQ 69 >4GN1-A nrPDB Length = 255 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 13/88 (14%) Query: 265 PDREGWL-LKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGII---PLENLSIREVED 320 P+ EG L LK G+ K+WK+R+F+L + +YY K R ++ L+++++ +D Sbjct: 132 PEIEGVLWLKDDGK-KSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQD 190 Query: 321 PRKP------NCFELYNP--SHKGQVIK 340 R C L +P K Q IK Sbjct: 191 YRNKYKAPTDYCLVLKHPQIQKKSQYIK 218 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6BBQ-A nrPDB 566 e-162 2R09-A nrPDB 557 e-159 4JWL-A nrPDB 325 1e-89 4A4P-A nrPDB 311 4e-85 3LTL-A nrPDB 282 1e-76 5NLY-A nrPDB 280 1e-75 3SWV-A nrPDB 275 2e-74 6FAE-A nrPDB 271 4e-73 1XSZ-A nrPDB 268 3e-72 4C7P-A nrPDB 266 1e-71 4OIY-A nrPDB 263 8e-71 1KU1-A nrPDB 251 6e-67 4D7R-A nrPDB 243 8e-65 4D7Q-A nrPDB 243 1e-64 1XT0-B nrPDB 242 2e-64 1RE0-B nrPDB 242 2e-64 1V5U-A nrPDB 115 4e-26 4GZU-A nrPDB 115 4e-26 4H6Y-A nrPDB 114 1e-25 5A3F-A nrPDB 104 6e-23 5KCV-A nrPDB 92 5e-19 2UVM-A nrPDB 89 4e-18 Sequences not found previously or not previously below threshold: 4UUD-B nrPDB 94 1e-19 6DLV-b nrPDB 92 5e-19 1DYN-A nrPDB 89 4e-18 2YS1-A nrPDB 79 3e-15 2X18-A nrPDB 76 3e-14 3TCA-A nrPDB 44 9e-05 1KFU-L nrPDB 44 1e-04 6E31-A nrPDB 44 1e-04 2DHI-A nrPDB 44 1e-04 3FM8-C nrPDB 44 1e-04 1B55-A nrPDB 42 4e-04 4Y93-A nrPDB 42 4e-04 2DHJ-A nrPDB 42 6e-04 4GN1-A nrPDB 41 0.001 3VIA-A nrPDB 41 0.001 3A8P-A nrPDB 40 0.001 3HK0-A nrPDB 40 0.001 5L81-A nrPDB 40 0.002 5FNO-A nrPDB 39 0.005 2J59-M nrPDB 39 0.005 4A6K-A nrPDB 39 0.005 4K81-A nrPDB 39 0.006 2YS3-A nrPDB 39 0.006 1WI1-A nrPDB 37 0.010 3K5H-A nrPDB 37 0.013 2D9Z-A nrPDB 37 0.014 2D9V-A nrPDB 36 0.022 2LUL-A nrPDB 36 0.024 2DTC-A nrPDB 35 0.047 4K2O-A nrPDB 34 0.089 2HQR-A nrPDB 33 0.21 2HMA-A nrPDB 33 0.24 2PLN-A nrPDB 32 0.33 2HQO-A nrPDB 32 0.41 1B43-A nrPDB 32 0.42 1RVY-A nrPDB 32 0.49 4BBK-A nrPDB 32 0.52 6EZ3-A nrPDB 31 0.87 2COF-A nrPDB 30 1.3 2COA-A nrPDB 30 1.6 2NNH-A nrPDB 30 1.8 2PG7-A nrPDB 30 2.4 3ORY-A nrPDB 30 2.4 5ZQM-A nrPDB 30 2.5 3PVW-A nrPDB 29 3.1 1EJI-A nrPDB 29 3.6 >6BBQ-A nrPDB Length = 520 Score = 566 bits (1459), Expect = e-162, Method: Composition-based stats. Identities = 337/341 (98%), Positives = 337/341 (98%) Query: 59 EESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 118 TTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD Sbjct: 7 HHGSTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 66 Query: 119 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 178 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL Sbjct: 67 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 126 Query: 179 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 238 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN Sbjct: 127 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 186 Query: 239 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 298 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY Sbjct: 187 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 246 Query: 299 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 358 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY Sbjct: 247 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 306 Query: 359 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 399 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK Sbjct: 307 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 347 >2R09-A nrPDB Length = 347 Score = 557 bits (1435), Expect = e-159, Method: Composition-based stats. Identities = 335/341 (98%), Positives = 336/341 (98%) Query: 59 EESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 118 TTQRN QIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD Sbjct: 7 HHGSTTQRNAQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 66 Query: 119 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 178 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL Sbjct: 67 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 126 Query: 179 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 238 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN Sbjct: 127 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 186 Query: 239 LYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 298 LYESIKNEPFKIPEDDGNDLT+TFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY Sbjct: 187 LYESIKNEPFKIPEDDGNDLTYTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEY 246 Query: 299 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 358 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY Sbjct: 247 TTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY 306 Query: 359 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 399 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK Sbjct: 307 RISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK 347 >4JWL-A nrPDB Length = 217 Score = 325 bits (834), Expect = 1e-89, Method: Composition-based stats. Identities = 167/198 (84%), Positives = 185/198 (93%) Query: 59 EESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGD 118 SKT QRN+++AMGRKKFNMDPKKGIQFL+EN+LLQ++PE++A+FLYKGEGLNKT IGD Sbjct: 20 HMSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGD 79 Query: 119 YLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL 178 YLGER++ N+ VL AFV+LHEF DLNLVQALRQFLWSFRLPGEAQKIDRMMEAFA RYCL Sbjct: 80 YLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCL 139 Query: 179 CNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRN 238 CNPGVFQSTDTCYVLSFA+IMLNTSLHN NVRDKP ERF+ MNRGINEGGDLPEELLRN Sbjct: 140 CNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRN 199 Query: 239 LYESIKNEPFKIPEDDGN 256 LY+SI+NEPFKIPEDDGN Sbjct: 200 LYDSIRNEPFKIPEDDGN 217 >4A4P-A nrPDB Length = 192 Score = 311 bits (796), Expect = 4e-85, Method: Composition-based stats. Identities = 167/186 (89%), Positives = 176/186 (94%) Query: 67 NKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDF 126 NKQ+AMGRKKFNMDPKKGIQFLIENDLL+++ ED+AQFLYKGEGLNKT IGDYLGERD+F Sbjct: 7 NKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEF 66 Query: 127 NIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQS 186 NI+VL AFVELHEF DLNLVQALRQFLWSFRLPGEAQKIDRMMEAFA RYC CN GVFQS Sbjct: 67 NIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQS 126 Query: 187 TDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNE 246 TDTCYVLSFAIIMLNTSLHN NV+DKPT ERFI MNRGIN+GGDLPEELLRNLYESIKNE Sbjct: 127 TDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNE 186 Query: 247 PFKIPE 252 PFKIPE Sbjct: 187 PFKIPE 192 >3LTL-A nrPDB Length = 211 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 95/190 (50%), Positives = 132/190 (69%), Gaps = 2/190 (1%) Query: 65 QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERD 124 Q+ + I G FN PK+GIQ+L E +L ++PED+AQFL++ E L+ T +G++LG+ D Sbjct: 17 QQKEIIEQGIDLFNKKPKRGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDND 76 Query: 125 DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPG-- 182 FN +V+ A+V+ H+F+ + V ALR FL FRLPGEAQKIDR+ME FA+RY CN G Sbjct: 77 KFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQT 136 Query: 183 VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYES 242 +F S DT YVL+++IIML T LH+ V++K T E++I MNRGIN+ DLPEE L +Y Sbjct: 137 LFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNE 196 Query: 243 IKNEPFKIPE 252 I + + E Sbjct: 197 IAGKKISMKE 206 >5NLY-A nrPDB Length = 405 Score = 280 bits (715), Expect = 1e-75, Method: Composition-based stats. Identities = 83/199 (41%), Positives = 127/199 (63%), Gaps = 6/199 (3%) Query: 61 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL 120 S R + +G FN P+KG+Q+LIE + +P VA FL + +GL++ +IG++L Sbjct: 39 SNDVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFL 98 Query: 121 GERD-DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLC 179 G R FN VL V+ +F+ + L +ALR+F R+ GEAQK++R++EAF+ RYC+C Sbjct: 99 GNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCIC 158 Query: 180 NPGV---FQSTDTCYVLSFAIIMLNTSLHNHNVRD--KPTAERFITMNRGINEGGDLPEE 234 NPGV F++ DT ++L+FAII+LNT +++ NV+ K E FI RG+++G D+P E Sbjct: 159 NPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPRE 218 Query: 235 LLRNLYESIKNEPFKIPED 253 +L +YE I+ K ED Sbjct: 219 MLMGIYERIRKRELKTNED 237 >3SWV-A nrPDB Length = 202 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 96/190 (50%), Positives = 132/190 (69%), Gaps = 2/190 (1%) Query: 65 QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERD 124 Q+ + I G + FN PK+GIQFL E +L +S ED+AQFL++ E L+ T +GD+LG+ Sbjct: 8 QQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSA 67 Query: 125 DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPG-- 182 FN +V+ A+V+ +F + V ALR FL FRLPGEAQKIDR+ME FA+RY CN G Sbjct: 68 RFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQT 127 Query: 183 VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYES 242 +F S DT YVL+++IIML T LH+ V++K T E++I MNRGIN+ DLPEE L ++YE Sbjct: 128 LFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEE 187 Query: 243 IKNEPFKIPE 252 I+ + + E Sbjct: 188 IEGKKIAMKE 197 >6FAE-A nrPDB Length = 371 Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 75/199 (37%), Positives = 125/199 (62%), Gaps = 6/199 (3%) Query: 61 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL 120 + + + +G FN P+KGIQ+LIE L +P VA F+ + +GL++ +IG++L Sbjct: 20 NNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFL 79 Query: 121 GERD-DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLC 179 G R FN VL V+ +F+ ++L ALR+F R+ GEAQK++R++EAF+ RYC+C Sbjct: 80 GNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVC 139 Query: 180 NPGV---FQSTDTCYVLSFAIIMLNTSLHNHNVRD--KPTAERFITMNRGINEGGDLPEE 234 NP + F++ DT ++L+FAII+LNT +++ +V+ K + FI RG++ G D+P + Sbjct: 140 NPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRD 199 Query: 235 LLRNLYESIKNEPFKIPED 253 LL +Y+ I+ + +D Sbjct: 200 LLVGIYQRIQGRELRTNDD 218 >1XSZ-A nrPDB Length = 356 Score = 268 bits (685), Expect = 3e-72, Method: Composition-based stats. Identities = 77/201 (38%), Positives = 114/201 (56%), Gaps = 8/201 (3%) Query: 74 RKKFNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKV 130 + FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +V Sbjct: 15 IEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQV 74 Query: 131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTC 190 L+AF F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Sbjct: 75 LKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAA 134 Query: 191 YVLSFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPF 248 Y+L+F IMLNT LHN ++ ++K T + RG N GGD + L LY IK +PF Sbjct: 135 YLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPF 194 Query: 249 K---IPEDDGNDLTHTFFNPD 266 + + G +LT T N D Sbjct: 195 ELNFVKTSPGYELTSTTLNKD 215 >4C7P-A nrPDB Length = 402 Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats. Identities = 77/201 (38%), Positives = 114/201 (56%), Gaps = 8/201 (3%) Query: 74 RKKFNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKV 130 + FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +V Sbjct: 41 IEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQV 100 Query: 131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTC 190 L+AF F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Sbjct: 101 LKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAA 160 Query: 191 YVLSFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPF 248 Y+L+F IMLNT LHN ++ ++K T + RG N GGD + L LY IK +PF Sbjct: 161 YLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPF 220 Query: 249 K---IPEDDGNDLTHTFFNPD 266 + + G +LT T N D Sbjct: 221 ELNFVKTSPGYELTSTTLNKD 241 >4OIY-A nrPDB Length = 191 Score = 263 bits (673), Expect = 8e-71, Method: Composition-based stats. Identities = 84/184 (45%), Positives = 115/184 (62%), Gaps = 1/184 (0%) Query: 66 RNKQIAMGRKKFNMDPKKGIQFLIENDLLQS-SPEDVAQFLYKGEGLNKTVIGDYLGERD 124 R ++ FN PKK I LI+ L+ SP +A++L + EGL+ +GDYLGE D Sbjct: 8 RKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGD 67 Query: 125 DFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVF 184 D NI ++ AFV+ +F +++V ALR FL SFRLPGE QKIDR M FA R+ NPGVF Sbjct: 68 DKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPGVF 127 Query: 185 QSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIK 244 DT YVLS+++IMLNT LH+ +++K + + F+ N GI+ G DLP + L L+ I Sbjct: 128 SKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIA 187 Query: 245 NEPF 248 N Sbjct: 188 NNEI 191 >1KU1-A nrPDB Length = 230 Score = 251 bits (640), Expect = 6e-67, Method: Composition-based stats. Identities = 72/218 (33%), Positives = 112/218 (51%), Gaps = 20/218 (9%) Query: 58 VEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLL-QSSPEDVAQFLYKGEG-LNKTV 115 V R + FN PKKGI LIE + S +D+A+FL+ +NK Sbjct: 15 VPRGSHMDRKTEFIECTNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKT 74 Query: 116 IGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASR 175 IG L D + +L ++ L +F+ L + +A+R L FRLPGE+Q+I+R++EAF+S Sbjct: 75 IGLLLCHPD--KVSLLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSA 132 Query: 176 YCL---CNPG------------VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIT 220 YC +P V D+ ++LS++IIMLNT LHN V++ + E + Sbjct: 133 YCENQDYDPSKISDNAEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVKEHMSFEDYSG 192 Query: 221 MNRGINEGGDLPEELLRNLYESIKNEPFKIPED-DGND 257 +G D P L +Y SI+++ +PE+ GN+ Sbjct: 193 NLKGCCNHKDFPFWYLDRVYCSIRDKEIVMPEEHHGNE 230 >4D7R-A nrPDB Length = 400 Score = 243 bits (621), Expect = 8e-65, Method: Composition-based stats. Identities = 74/202 (36%), Positives = 113/202 (55%), Gaps = 9/202 (4%) Query: 74 RKKFNMDPKKGIQFLIE--NDLLQSSPEDVAQFLYKGE-GLNKTVIGDYLGERDDFNIKV 130 K FN PK GI + + D Q + A+ Y+ + LN +GDYLG N KV Sbjct: 38 IKLFNDKPKSGIARIKKWCTDNNQDFIAETAKIFYEEKSNLNLEFVGDYLGTDGVDNQKV 97 Query: 131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGV-FQSTDT 189 L++F + +F + + +++LR+FL SF+LPGEAQKIDR++E+F + Y N + S D Sbjct: 98 LESFTKQFDFKEKDYLESLRRFLQSFKLPGEAQKIDRLVESFGTHYYEQNLNIDINSKDA 157 Query: 190 CYVLSFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEP 247 Y+L++ IMLNT LHN ++ K T E+ +G NE + + L+ +Y+ I+ +P Sbjct: 158 AYILAYQTIMLNTDLHNPSIAKSKKMTFEQLKNNLKGTNESKNFNDNFLKKIYDEIEAKP 217 Query: 248 FK---IPEDDGNDLTHTFFNPD 266 FK + G +LT T N D Sbjct: 218 FKLNFVKTSPGYELTSTTLNKD 239 >4D7Q-A nrPDB Length = 352 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 93/321 (28%), Positives = 148/321 (46%), Gaps = 19/321 (5%) Query: 74 RKKFNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKV 130 + FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +V Sbjct: 19 IEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQV 78 Query: 131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTC 190 L+AF F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Sbjct: 79 LKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAA 138 Query: 191 YVLSFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPF 248 Y+L+F IMLNT LHN ++ ++K T RG N GGD + L LY IK +PF Sbjct: 139 YLLAFQTIMLNTDLHNPSIPEKNKMTVYGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPF 198 Query: 249 KIP---EDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWF--ILTDNCLYYFEYTT--- 300 ++ G + + D+ L K + F + +N F+ Sbjct: 199 ELNFVDSSPGYQINNISSQNDKTFKQLNQFLEEKRNIQNIFPKLQNNNLTIEFKNPKTFL 258 Query: 301 ---DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVV 357 +I + S KP+ F + K ++I E + E + Sbjct: 259 SKFTGYKGSVIIKDEKSGAAEIQVYKPSIFSRWFLGEKSKIIIQPLREEGRQPSEQS--- 315 Query: 358 YRISAPSPEEKEEWMKSIKAS 378 +++A E + SIKA+ Sbjct: 316 LKLAAQITASFETKVTSIKAT 336 >1XT0-B nrPDB Length = 203 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 71/183 (38%), Positives = 107/183 (58%), Gaps = 5/183 (2%) Query: 74 RKKFNMDPKKGIQFLIE-NDLLQSSP-EDVAQFLYKG-EGLNKTVIGDYLGERDDFNIKV 130 + FN PK GI + E + + SP E++A+F ++ + L+ +GDYL + N +V Sbjct: 15 IEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQV 74 Query: 131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTC 190 L+AF F + V+ LR FL +F+LPGEAQKIDR++++F+ Y NP V + D Sbjct: 75 LKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAA 134 Query: 191 YVLSFAIIMLNTSLHNHNV--RDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPF 248 Y+L+F IMLNT LHN ++ ++K T + RG N GGD + L LY IK +PF Sbjct: 135 YLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPF 194 Query: 249 KIP 251 ++ Sbjct: 195 ELN 197 >1RE0-B nrPDB Length = 221 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 74/218 (33%), Positives = 107/218 (49%), Gaps = 29/218 (13%) Query: 63 TTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQ-SSPEDVAQFLYKGEG-LNKTVIGDYL 120 + R + + + FN KKGIQ LIE + S D+A FL+ G LNK IG L Sbjct: 5 ASDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLL 64 Query: 121 GERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN 180 D +L+ F++L +F L + +A+R L FRLPGE+Q+I+R++EAF+S+Y Sbjct: 65 C--DPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQ 122 Query: 181 PG-------------------------VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTA 215 V D+ +VLS++IIMLNT HN V+D T Sbjct: 123 SNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTF 182 Query: 216 ERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPED 253 + + RG G D P L +Y SIK + +PE+ Sbjct: 183 DDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEE 220 >1V5U-A nrPDB Length = 117 Score = 115 bits (288), Expect = 4e-26, Method: Composition-based stats. Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 20/120 (16%) Query: 268 EGWLLKLGGRVKTWKRRWFIL--TDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPN 325 EG L K G +K WK RWF+L T + L Y+++ D E +G+I L + E P P Sbjct: 11 EGILYKKGAFMKPWKARWFVLDKTKHQLRYYDHRMDTECKGVIDLAEV---EAVAPGTP- 66 Query: 326 CFELYNPSHKGQVIKACKTEADGRV--VEGNHVVYRISAPSPEEKEEWMKSIKASISRDP 383 I A KT + V+ VY A ++W+ I++ +S P Sbjct: 67 ------------TIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSSGP 114 >4GZU-A nrPDB Length = 501 Score = 115 bits (287), Expect = 4e-26, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 45/118 (38%), Gaps = 25/118 (21%) Query: 269 GWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSI---REVEDPRKPN 325 G+LL+ W++ W + T+ CL++++ D P +PL S+ RE + K Sbjct: 404 GYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDY 463 Query: 326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDP 383 F+L SH VY A S E WM IK + S Sbjct: 464 VFKLQFKSH----------------------VYFFRAESKYTFERWMDVIKRASSSPG 499 >4H6Y-A nrPDB Length = 501 Score = 114 bits (284), Expect = 1e-25, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 25/117 (21%) Query: 269 GWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSI---REVEDPRKPN 325 G LL+ W++ W + T+ CL++++ D P +PL S+ E E+ +K Sbjct: 403 GNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDY 462 Query: 326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 F+L+ SH VY A S E WM+ I+++ S Sbjct: 463 VFKLHFKSH----------------------VYYFRAESEYTFERWMEVIRSATSSA 497 >5A3F-A nrPDB Length = 754 Score = 104 bits (260), Expect = 6e-23, Method: Composition-based stats. Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 22/123 (17%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDP--R 322 R+GWL +G K WF+LT L +++ +KE + ++PL+NL +R+VE Sbjct: 518 RKGWLTISNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMS 577 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + F L+N + R V ++ ++ S E+ + W KAS+ R Sbjct: 578 SKHIFALFN--------------TEQRNVYKDYRFLELACDSQEDVDSW----KASLLRA 619 Query: 383 PFY 385 Y Sbjct: 620 GVY 622 >4UUD-B nrPDB Length = 864 Score = 93.6 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 22/123 (17%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED--PR 322 R+GWL +G K WF+LT L +++ +KE + ++ ++NL +R+VE Sbjct: 522 RKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMS 581 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + F L+N + R V ++ ++ + EE + W KAS R Sbjct: 582 SKHIFALFN--------------TEQRNVYKDYRQLELACETQEEVDSW----KASFLRA 623 Query: 383 PFY 385 Y Sbjct: 624 GVY 626 >6DLV-b nrPDB Length = 748 Score = 91.7 bits (226), Expect = 5e-19, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 22/123 (17%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED--PR 322 R+GWL +G K WF+LT L +++ +KE + ++ ++NL +R+VE Sbjct: 522 RKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMS 581 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + F L+N + R V ++ ++ + EE + W KAS R Sbjct: 582 SKHIFALFN--------------TEQRNVYKDYRQLELACETQEEVDSW----KASFLRA 623 Query: 383 PFY 385 Y Sbjct: 624 GVY 626 >5KCV-A nrPDB Length = 460 Score = 91.7 bits (226), Expect = 5e-19, Method: Composition-based stats. Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 29/119 (24%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLY--YFEYTTDKEPRGIIPLENLSIRE-----VE 319 +EGWL K G +KTW+ R+F+L ++ + Y E D + R PL N S+ + E Sbjct: 22 KEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRE-APLNNFSVAQCQLMKTE 80 Query: 320 DPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR-ISAPSPEEKEEWMKSIKA 377 PR PN F + R ++ V+ R +PEE+EEW +I+ Sbjct: 81 RPR-PNTFII-------------------RCLQWTTVIERTFHVETPEEREEWTTAIQT 119 >1DYN-A nrPDB Length = 125 Score = 89.0 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 22/123 (17%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED--PR 322 R+GWL +G K WF+LT L +++ +KE + ++ ++NL +R+VE Sbjct: 14 RKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMS 73 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + F L+N + R V ++ ++ + EE + W KAS R Sbjct: 74 SKHIFALFN--------------TEQRNVYKDYRQLELACETQEEVDSW----KASFLRA 115 Query: 383 PFY 385 Y Sbjct: 116 GVY 118 >2UVM-A nrPDB Length = 123 Score = 88.6 bits (218), Expect = 4e-18, Method: Composition-based stats. Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 29/119 (24%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLY--YFEYTTDKEPRGIIPLENLSIRE-----VE 319 +EGWL K G +KTW+ R+F+L ++ + Y E D + R PL N S+ + E Sbjct: 8 KEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRE-APLNNFSVAQCQLMKTE 66 Query: 320 DPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR-ISAPSPEEKEEWMKSIKA 377 PR PN F + R ++ V+ R +PEE+EEW +I+ Sbjct: 67 RPR-PNTFII-------------------RCLQWTTVIERTFHVETPEEREEWTTAIQT 105 >2YS1-A nrPDB Length = 113 Score = 79.0 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 22/122 (18%) Query: 267 REGWLL--KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED--PR 322 R GWL + K WF+LT L +++ +KE + ++PL+NL IR+VE Sbjct: 10 RRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMS 69 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + F ++N + R V + ++ S E+ + W KAS R Sbjct: 70 NKHVFAIFN--------------TEQRNVYKDLRQIELACDSQEDVDSW----KASFLRA 111 Query: 383 PF 384 Sbjct: 112 GV 113 >2X18-A nrPDB Length = 119 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 30/123 (24%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLY--YFEYTTDKEPRGIIPLENLSIR-----EVE 319 +EGW+ K G +K W+ R+F+L + + Y E D + PL N S+ + E Sbjct: 9 KEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPY--PLNNFSVAKCQLMKTE 66 Query: 320 DPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR-ISAPSPEEKEEWMKSIKAS 378 P KPN F + R ++ V+ R +PEE+EEW ++I+A Sbjct: 67 RP-KPNTFII-------------------RCLQWTTVIERTFHVDTPEEREEWTEAIQAV 106 Query: 379 ISR 381 R Sbjct: 107 ADR 109 >3TCA-A nrPDB Length = 291 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 64/174 (36%), Gaps = 22/174 (12%) Query: 216 ERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLG 275 + F N+G E + E++ + KN+ + + E + P+ EG L Sbjct: 128 QNFYLDNKGKKENKETNEKM------NAKNKEYLLEES---FCGTSIIVPELEGALYLKE 178 Query: 276 GRVKTWKRRWFILTDNCLYYF---EYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNP 332 K+WKRR+F+L + +YY + T ++ I EN++I + + Sbjct: 179 DGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNI----------YYGIQCK 228 Query: 333 SHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYD 386 C ++ + + + + +W+ I+ + YD Sbjct: 229 MKYKAPTDHCFVLKHPQIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYD 282 >1KFU-L nrPDB Length = 699 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 28/185 (15%), Positives = 69/185 (37%), Gaps = 22/185 (11%) Query: 28 RRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESK-------TTQRNKQIAMGRKKFNM- 79 RRR++++ +D+ + + I EV E+ T++ SK +R+ R+ N Sbjct: 415 RRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRF 474 Query: 80 DPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHE 139 G L+ + + D ++ + + + D + +A +E + Sbjct: 475 KLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEI-----------EANLEEFD 523 Query: 140 FADLNLVQALRQFLWSFRLPGEAQKIDRM-MEAFASRYCLCNPGVFQSTDTCYVLSFAII 198 ++ ++ +R+ +L GE +I ++ R + + + Sbjct: 524 ISEDDIDDGVRRLFA--QLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 581 Query: 199 MLNTS 203 ML++ Sbjct: 582 MLDSD 586 >6E31-A nrPDB Length = 359 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 64/174 (36%), Gaps = 22/174 (12%) Query: 216 ERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLG 275 + F N+G E + E++ + KN+ + + E + P+ EG L Sbjct: 196 QNFYLDNKGKKENKETNEKM------NAKNKEYLLEES---FCGTSIIVPELEGALYLKE 246 Query: 276 GRVKTWKRRWFILTDNCLYYF---EYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNP 332 K+WKRR+F+L + +YY + T ++ I EN++I + + Sbjct: 247 DGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNI----------YYGIQCK 296 Query: 333 SHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYD 386 C ++ + + + + +W+ I+ + YD Sbjct: 297 MKYKAPTDHCFVLKHPQIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYD 350 >2DHI-A nrPDB Length = 120 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 15/120 (12%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNC-LYYFEY--TTDKEPRGIIPLENLSIREVEDPRK 323 + GWLL+ +K WK+ WF L + L Y++ E + +P++ ++IR + Sbjct: 10 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIRTGHE--- 66 Query: 324 PNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDP 383 C ++ P K + DG+ + + A S ++ W +++ S + P Sbjct: 67 --CRDIQPPDGKPRDCLLQIVCRDGKTIS-------LCAESTDDCLAWKFTLQDSRTSGP 117 >3FM8-C nrPDB Length = 392 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 44/116 (37%), Gaps = 14/116 (12%) Query: 267 REGWLLKLG-GRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPN 325 +EG++ K G + + +++RWF + D L YF+ D RG + I E Sbjct: 273 KEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARG-----EVFIGSKESG---- 323 Query: 326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISR 381 Y H G + + + + ++ EW+ + + ++ R Sbjct: 324 ----YTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDR 375 Score = 36.2 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 3/90 (3%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDN--CLYYFEYTTDKEPRGIIPLENLSIR-EVEDPRK 323 REG+L K G + R F+LT+ L YF KEP+ ++ +E+L+ + Sbjct: 150 REGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGH 209 Query: 324 PNCFELYNPSHKGQVIKACKTEADGRVVEG 353 P+ ++ E +V+ Sbjct: 210 PHGLQVTYLKDNSTRNIFIYHEDGKEIVDW 239 >1B55-A nrPDB Length = 169 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 30/126 (23%), Positives = 52/126 (41%), Gaps = 14/126 (11%) Query: 268 EGWLLKLGGRVK-----TWKRRWFILTDNCLYYFEYTTDK----EPRGIIPLENLSIREV 318 E LK + K +K+R F+LT + L Y+EY ++ +G I +E ++ E Sbjct: 6 ESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVET 65 Query: 319 EDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY-----RISAPSPEEKEEWMK 373 P K E P + + + R VVY + +P+ E ++ W+ Sbjct: 66 VVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIH 125 Query: 374 SIKASI 379 +K I Sbjct: 126 QLKNVI 131 >4Y93-A nrPDB Length = 446 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Query: 268 EGWLLKLGGRVK-----TWKRRWFILTDNCLYYFEYTTDK----EPRGIIPLENLSIREV 318 E LK + K +K+R F+LT L Y+EY ++ +G I +E ++ E Sbjct: 8 ESIFLKRSQQKKKTSPLNFKKRLFLLTVQKLSYYEYDFERGRRGSKKGSIDVEKITCVET 67 Query: 319 EDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVY-----RISAPSPEEKEEWMK 373 P K E P + + + R VVY + +P+ E ++ W+ Sbjct: 68 VVPEKNPPPERQIPRRGEESSETEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIH 127 Query: 374 SIKASI 379 +K I Sbjct: 128 QLKNVI 133 >2DHJ-A nrPDB Length = 125 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 50/130 (38%), Gaps = 31/130 (23%) Query: 267 REGWLL----------KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIR 316 +EGWL ++GG ++ WK+ + +L + LY ++ ++ + Sbjct: 11 KEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQT----------TPS 60 Query: 317 EVEDPRKPN-CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSI 375 E E P N C + S + T +D + A ++ W+K+I Sbjct: 61 EEEQPISVNACLIDISYSETKRKNVFRLTTSDCECL--------FQAEDRDDMLAWIKTI 112 Query: 376 KAS--ISRDP 383 + S ++ P Sbjct: 113 QESSNLNSGP 122 >4GN1-A nrPDB Length = 255 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 20/117 (17%), Positives = 45/117 (38%), Gaps = 13/117 (11%) Query: 265 PDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGI---IPLENLSIREVEDP 321 P+ EG L K+WK+R+F+L + +YY K R + + L+++++ +D Sbjct: 132 PEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDY 191 Query: 322 RKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKAS 378 R C ++ + + + + +W+ I+ + Sbjct: 192 RNKY----------KAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIA 238 >3VIA-A nrPDB Length = 112 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 49/115 (42%), Gaps = 15/115 (13%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNC-LYYFEY--TTDKEPRGIIPLENLSIREVEDPRK 323 + GWLL+ +K WK+ WF L + L Y++ + E + +P++ ++IR ++ R Sbjct: 7 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECR- 65 Query: 324 PNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKAS 378 Q + ++V + + A S ++ W +++ S Sbjct: 66 -----------DTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDS 109 >3A8P-A nrPDB Length = 263 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 37/120 (30%), Gaps = 18/120 (15%) Query: 262 FFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDP 321 +R+ L+ + WK+ W L L ++E E Sbjct: 24 TLQKERKLELVAR----RKWKQYWVTLKGCTLLFYET--------------YGKNSTEQN 65 Query: 322 RKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISR 381 P C S V + K E + VY A S + E W+ +I ++ + Sbjct: 66 SAPRCALFAEDSIVQSVPEHPKKEHVFCLSNSCGDVYLFQATSQTDLENWVTAIHSACAS 125 >3HK0-A nrPDB Length = 256 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 58/150 (38%), Gaps = 22/150 (14%) Query: 257 DLTHTFFN----PDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRG---IIP 309 L F N P+ +G+L K+WK+ + L + LY T PR + Sbjct: 120 QLLQNFLNSSSSPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSAAPRHLQLLAD 179 Query: 310 LENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKE 369 LE+ +I + RK P+ G IK K + + + + A + + Sbjct: 180 LEDSNIFSLIAGRKQY----NAPTDHGLCIKPNKVRNETKELRL------LCAEDEQTRT 229 Query: 370 EWMKSIKASISRDPFYDMLATRKRRIANKK 399 WM + + + + Y ML + RI ++ Sbjct: 230 SWMTAFR--LLK---YGMLLYQNYRIPQQR 254 >5L81-A nrPDB Length = 150 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 34/79 (43%), Gaps = 3/79 (3%) Query: 278 VKTWKRRWFILTDNCLYYFEYTTDK--EPRGIIPLENLS-IREVEDPRKPNCFELYNPSH 334 +K +++ W + D L Y++ + +P + L+ + +V + C +L PS Sbjct: 37 LKGYRQYWVVFKDTTLSYYKSQDEAPGDPTQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 96 Query: 335 KGQVIKACKTEADGRVVEG 353 +G + + + + + Sbjct: 97 EGMSEIYLRCQDEQQYAQW 115 >5FNO-A nrPDB Length = 605 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 41/133 (30%), Gaps = 19/133 (14%) Query: 247 PFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRG 306 P I + G DLT+T + D WLL + +N L++ + P Sbjct: 242 PLAIKTNVGADLTYTPLDTDNNNWLLAK-----------IMFNNNDLFHGQIFHVAYPHA 290 Query: 307 IIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEA--------DGRVVEGNHVVY 358 I + +L+ R P + ++ ++ + +VY Sbjct: 291 IAEIVHLAALRTMSARHPVLALMERLMYQAYAVRPLGERVLFNKGGLFEQNFAYPQDMVY 350 Query: 359 RISAPSPEEKEEW 371 + S W Sbjct: 351 KFVGDSYPTTGRW 363 >2J59-M nrPDB Length = 168 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 47/124 (37%), Gaps = 29/124 (23%) Query: 267 REGWLL----------KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIR 316 +EGWL ++GG ++ WK+ + +L + LY ++ ++ + Sbjct: 5 KEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQT----------TPS 54 Query: 317 EVEDPRKPN-CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSI 375 E E P N C + S + T +D + A ++ W+K+I Sbjct: 55 EEEQPISVNACLIDISYSETKRKNVFRLTTSDCECL--------FQAEDRDDMLAWIKTI 106 Query: 376 KASI 379 + S Sbjct: 107 QESS 110 >4A6K-A nrPDB Length = 120 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 48/120 (40%), Gaps = 3/120 (2%) Query: 263 FNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPR 322 F + G+L + +K++ + +++LT N + E+ T + ++P+ +L++ E Sbjct: 4 FTEIKSGFLERRSKFLKSYSKGYYVLTPN--FLHEFKTADRKKDLVPVMSLALSECTVTE 61 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 +P+ G K ++ H + A S E W ++K S Sbjct: 62 HSRKNSTSSPNSTGSDAKFVLHAKQNGIIRRGHN-WVFKADSYESMMSWFDNLKILTSTS 120 >4K81-A nrPDB Length = 258 Score = 38.5 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 41/119 (34%), Gaps = 9/119 (7%) Query: 258 LTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIRE 317 L+ + + P+ G+L K+WK+ +F L + LY+ T PR + + Sbjct: 131 LSSSTY-PEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSAAPRHLQFFSEFGNSD 189 Query: 318 VEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIK 376 + H + + G + + A + + W+ +I+ Sbjct: 190 I------YVSLAGKKKHGAPTNYGFCFKPNKA--GGPRDLKMLCAEEEQSRTCWVTAIR 240 >2YS3-A nrPDB Length = 137 Score = 38.5 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 33/80 (41%), Gaps = 5/80 (6%) Query: 278 VKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLS----IREVEDPRKPNCFELYNPS 333 +K +++ W + + L Y++ D+ P I NL + +V + C +L PS Sbjct: 25 LKGYRQHWVVFKETTLSYYKS-QDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPS 83 Query: 334 HKGQVIKACKTEADGRVVEG 353 +G + + + + Sbjct: 84 PEGMSEIYLRCQDEQQYARW 103 >1WI1-A nrPDB Length = 126 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 42/102 (41%), Gaps = 7/102 (6%) Query: 269 GWLLKLGGRV-KTWKRRWFILTDNCLYYFE----YTTDKEPRGIIPLENLSIREVE-DPR 322 G+L +G V K WK+R+F+L Y F EP+ ++ L+ ++ + P Sbjct: 12 GYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPG 71 Query: 323 KPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPS 364 +N +G + + R++ +YR + S Sbjct: 72 LEGGRAFFNAVKEGDTVIFASDDEQDRIL-WVQAMYRATGQS 112 >3K5H-A nrPDB Length = 403 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 41/189 (21%) Query: 17 SLEEREELLDIRRRKKELIDDIERL-KYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRK 75 S +ERE + + + + +IE + Y + EV +E+ +E S R Q Sbjct: 73 SFKEREAVRQLAKTCDVVTAEIEHVDTYALEEVASEV----KIEPSWQAIRTIQ-----N 123 Query: 76 KFNMDP---KKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQ 132 KFN K GI +L++++P ++A+ +G+ LG K + Sbjct: 124 KFNQKEHLRKYGIPMAEHRELVENTPAELAK------------VGEQLGYPLMLKSKTM- 170 Query: 133 AFVELHEF---ADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDT 189 A+ F + ++ +AL EA K DR + A Y V Sbjct: 171 AYDGRGNFRVNSQDDIPEAL-----------EALK-DRPLYAEKWAYFKMELAVIVVKTK 218 Query: 190 CYVLSFAII 198 VLS+ + Sbjct: 219 DEVLSYPTV 227 >2D9Z-A nrPDB Length = 129 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 51/124 (41%), Gaps = 14/124 (11%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENL----SIREVEDPR 322 +EGW++ R KR ++ L CL F+ + + IPL + S R+ + Sbjct: 10 KEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNIS 69 Query: 323 K---PNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379 + P+CFE+ + V + + V+ V ++ + W K+I+ ++ Sbjct: 70 QGSNPHCFEIITDTMVYFVGENNGDSSHNPVLAATGVGLDVA-------QSWEKAIRQAL 122 Query: 380 SRDP 383 P Sbjct: 123 MSGP 126 >2D9V-A nrPDB Length = 130 Score = 36.2 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 15/117 (12%) Query: 267 REGWLLKLGGRVKTWKRRWFIL-TDNCLYYF--EYTTDKEPRGIIPLENLSIREVEDPRK 323 R GWL + ++ WKR WF L D L Y+ E D+E R +I + ++R+++ ++ Sbjct: 10 RGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVI---HFNVRDIKVGQE 66 Query: 324 PNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASIS 380 C ++ P + + +G + + A + ++ W ++ + S Sbjct: 67 --CQDVQPPEGRSRDGLLTVNLREGSRLH-------LCAETRDDAIAWKTALMEANS 114 >2LUL-A nrPDB Length = 164 Score = 36.2 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 21/123 (17%) Query: 263 FNPDREGWLLKLGGRVK-----TWKRRWFILTDNCLYYFE-YTTDKEPRGIIPLENLSIR 316 FN E L+K + K +K R F+LT + L Y+E K +G I + + Sbjct: 13 FNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGRAEKKYRKGFIDVSKIKCV 72 Query: 317 EVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIK 376 E+ + C+ + +VV + +Y APSP+ ++ W+K +K Sbjct: 73 EIVK--------------NDDGVIPCQNKYPFQVVHDANTLYIF-APSPQSRDLWVKKLK 117 Query: 377 ASI 379 I Sbjct: 118 EEI 120 >2DTC-A nrPDB Length = 126 Score = 35.5 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 11/83 (13%) Query: 261 TFFNPDREGWLLKLGGR--VKTWKRRWFILTDNCLYYF---------EYTTDKEPRGIIP 309 T P R LLK G + + +W R W +L+ L Y+ P + Sbjct: 2 TMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGATLLYYGAKSLRGTDRKHYKSTPGKKVS 61 Query: 310 LENLSIREVEDPRKPNCFELYNP 332 + ++ +DP P+ F+L NP Sbjct: 62 IVGWMVQLPDDPEHPDIFQLNNP 84 >4K2O-A nrPDB Length = 276 Score = 34.3 bits (77), Expect = 0.089, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 37/109 (33%), Gaps = 28/109 (25%) Query: 281 WKRRWFILTDNCLYYFEY------TTDKEPRGIIPLENLSIREV-EDPRKPNCFELYNPS 333 WK W L L+++E + P+ + +EN ++ V E P+K F L N Sbjct: 36 WKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSL 95 Query: 334 HKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRD 382 + S E E W+ +I ++ + Sbjct: 96 GDA---------------------FLFQTTSQTELENWITAIHSACATA 123 >2HQR-A nrPDB Length = 223 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 28/114 (24%), Positives = 43/114 (37%), Gaps = 12/114 (10%) Query: 17 SLEEREELLDIRRRKKELIDDIERLKY--EIAEVMTEIDNLTSVEESKTTQRNKQIAMGR 74 SLE+ E L+DIR ++ D L + I E + I L S + + + G Sbjct: 32 SLEDGEYLMDIRNYDLVMVSDKNALSFVSRIKEKHSSIVVLVSSDNPTSEEEVHAFEQGA 91 Query: 75 KKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNI 128 + P + I+ L+ E +F G N IGD D+ I Sbjct: 92 DDYIAKPYRSIKALVAR------IEARLRFW----GSNVIEIGDLTISPDEEKI 135 >2HMA-A nrPDB Length = 376 Score = 33.1 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 18/160 (11%) Query: 92 DLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQ 151 + V L K +G + VIG ++ DD + + E ++ D+ V A + Sbjct: 15 GMSGGVDSSVTALLLKEQGYD--VIGIFMKNWDDTDENGVCTATE--DYKDVVAV-ADQI 69 Query: 152 FLWSFRLPGEAQKIDRMMEAFASRYCL---CNPGVFQSTDTCY--VLSFAIIM----LNT 202 + + + E + DR+ E F + Y NP V + + + L +AI + + T Sbjct: 70 GIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAITLGADYVAT 129 Query: 203 SLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYES 242 + RD+ + + M RG++ G D L L + Sbjct: 130 GHYARVARDE---DGTVHMLRGVDNGKD-QTYFLSQLSQE 165 >2PLN-A nrPDB Length = 137 Score = 32.4 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 32/77 (41%), Gaps = 2/77 (2%) Query: 17 SLEEREELLDIRRRKKELIDDIERLKY--EIAEVMTEIDNLTSVEESKTTQRNKQIAMGR 74 SLE+ E L+DIR ++ D L + I E + I L S + + + G Sbjct: 50 SLEDGEYLMDIRNYDLVMVSDKNALSFVSRIKEKHSSIVVLVSSDNPTSEEEVHAFEQGA 109 Query: 75 KKFNMDPKKGIQFLIEN 91 + P + I+ L+ Sbjct: 110 DDYIAKPYRSIKALVAR 126 >2HQO-A nrPDB Length = 123 Score = 32.4 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 32/77 (41%), Gaps = 2/77 (2%) Query: 17 SLEEREELLDIRRRKKELIDDIERLKY--EIAEVMTEIDNLTSVEESKTTQRNKQIAMGR 74 SLE+ E L+DIR ++ D L + I E + I L S + + + G Sbjct: 32 SLEDGEYLMDIRNYDLVMVSDKNALSFVSRIKEKHSSIVVLVSSDNPTSEEEVHAFEQGA 91 Query: 75 KKFNMDPKKGIQFLIEN 91 + P + I+ L+ Sbjct: 92 DDYIAKPYRSIKALVAR 108 >1B43-A nrPDB Length = 340 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 47/125 (37%), Gaps = 15/125 (12%) Query: 47 EVMTEIDNLTSVEESKTTQRNKQIAMGR---KKFNMDPKKGIQFLIENDLLQSSPEDVAQ 103 E+ E+ L V + R K I + +N KGI ++++ S + +A+ Sbjct: 204 EIKPELIILEEVLKELKLTREKLIELAILVGTDYNPGGIKGIGLKKALEIVRHSKDPLAK 263 Query: 104 FLYKGEGLNKTVIGDYLGER-----------DDFNIKVLQAFVELHEFADLNLVQALRQF 152 F K ++ I ++ D +L+ + H+F++ + L + Sbjct: 264 F-QKQSDVDLYAIKEFFLNPPVTDNYNLVWRDPDEEGILKFLCDEHDFSEERVKNGLERL 322 Query: 153 LWSFR 157 + + Sbjct: 323 KKAIK 327 >1RVY-A nrPDB Length = 483 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 12/83 (14%) Query: 84 GIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELH--EFA 141 G L LL+ + VA F+++G L + + D L+ F E + Sbjct: 403 GTPALTSRGLLEKDFQKVAHFIHRGIELTVQI------QDDTGPRATLKEFKEKLAGDEK 456 Query: 142 DLNLVQALRQ----FLWSFRLPG 160 V+ALRQ F F LPG Sbjct: 457 HQRAVRALRQEVESFAALFPLPG 479 >4BBK-A nrPDB Length = 165 Score = 32.0 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 37/98 (37%), Gaps = 15/98 (15%) Query: 277 RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKG 336 +K K+ WF+ D + YF+ +KE P+E L++R E N S + Sbjct: 41 MLKACKQYWFVFKDTSIAYFK---NKELEQGEPIEKLNLRGCE------IVPDVNVSGRK 91 Query: 337 QVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKS 374 IK ADG + ++ WM + Sbjct: 92 FGIKLLIPVADGMNE------VYLRCDHEDQYARWMAA 123 >6EZ3-A nrPDB Length = 234 Score = 31.2 bits (69), Expect = 0.87, Method: Composition-based stats. Identities = 30/194 (15%), Positives = 65/194 (33%), Gaps = 31/194 (15%) Query: 65 QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLG-ER 123 QR K + +G F + ++ + +S D L GE + + LG Sbjct: 18 QRKKHVILGISPFTSKYNE--SYIRKIIQWANSNFDDFSILLAGE--ESKNLLECLGYSS 73 Query: 124 DDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGV 183 N KV + F + ++ K ++ + R+ + Sbjct: 74 SKANQKVRKEIKRQIRFCEDEII-----------------KCNKTITNRIHRFSDFKNNI 116 Query: 184 FQSTDTCYVLSFAIIM--LNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYE 241 + Y+ + I+ NT + N K + + + + +N ++ +E L + Sbjct: 117 Y------YIDIYKTIVDQFNTDSNFKNSCLKMSLQALQSKGKNVNTSIEITDETLEYAAQ 170 Query: 242 SIKNE-PFKIPEDD 254 + E PF + + Sbjct: 171 YVLAELPFFLNANP 184 >2COF-A nrPDB Length = 107 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 2/73 (2%) Query: 281 WKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIK 340 WK RW + DN L++++ ++ PL + V DP + + + HKG+ + Sbjct: 22 WKSRWCSVRDNHLHFYQDR-NRSKVAQQPLSLVGCEVVPDPSPDHLYS-FRILHKGEELA 79 Query: 341 ACKTEADGRVVEG 353 + ++ + Sbjct: 80 KLEAKSSEEMGHW 92 >2COA-A nrPDB Length = 125 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 43/124 (34%), Gaps = 18/124 (14%) Query: 267 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVED------ 320 REGW++ + KR ++ L C+ F+ T IPL + E Sbjct: 10 REGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVP 69 Query: 321 PRK-PNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379 P P+CFE+ + V + G +G E W +I+ ++ Sbjct: 70 PGTNPHCFEIVTANATYFVGEMPGGTPGGPSGQGA-----------EAARGWETAIRQAL 118 Query: 380 SRDP 383 P Sbjct: 119 MSGP 122 >2NNH-A nrPDB Length = 476 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 22/142 (15%), Positives = 49/142 (34%), Gaps = 30/142 (21%) Query: 134 FVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCL-CNPGVFQSTDTCYV 192 F + ++ D N + +++F +FR+ S + CN F C+ Sbjct: 165 FQKRFDYKDQNFLTLMKRFNENFRI-------------LNSPWIQVCNN--FPLLIDCFP 209 Query: 193 LSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPE 252 + ++ N +L +R+K + +N D + L + + N+ + Sbjct: 210 GTHNKVLKNVALTRSYIREKVKEHQASLD---VNNPRDFIDCFLIKMEQEKDNQKSEFNI 266 Query: 253 DD-----------GNDLTHTFF 263 ++ G + T T Sbjct: 267 ENLVGTVADLFVAGTETTSTTL 288 >2PG7-A nrPDB Length = 476 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 29/166 (17%), Positives = 56/166 (33%), Gaps = 41/166 (24%) Query: 82 KKGIQFLI--ENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHE 139 K+GI+ I E L + G ++ T + R N+ F + + Sbjct: 120 KRGIEERIQEEAGFLIDALRGTG-----GANIDPT----FFLSRTVSNVISSIVFGDRFD 170 Query: 140 FADLNLVQALRQFLWSFR-------------------LPGEAQKIDRM---MEAFASRYC 177 + D + LR L F+ LPG Q+ ++ +E F ++ Sbjct: 171 YKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKV 230 Query: 178 LCNP-GVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMN 222 N + ++ ++ SF +I + N N E ++ Sbjct: 231 EHNQRTLDPNSPRDFIDSF-LIRMQEEEKNPNT------EFYLKNL 269 >3ORY-A nrPDB Length = 363 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 13/89 (14%), Positives = 36/89 (40%), Gaps = 16/89 (17%) Query: 81 PKKGIQFLIENDLLQSSPE------------DVAQFLYKGEGLNKTVIGDYLGERDDFNI 128 PKK +Q + ++ P+ + ++ + + + I + + D Sbjct: 261 PKKALQLVKAYGGIEKIPKPILKSPIEVDVIAIKKYFLQPQVTDNYRIEWHTPDPDAVKR 320 Query: 129 KVLQAFVELHEFADLNLVQALRQFLWSFR 157 + V+ H+F+ + AL +++ +F+ Sbjct: 321 IL----VDEHDFSIDRVSTALERYVKAFK 345 >5ZQM-A nrPDB Length = 309 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 5/84 (5%) Query: 17 SLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKK 76 S + REELL I R+ EL DD+ ++A + ++ + + + + +AM R+ Sbjct: 203 SAKGREELLRISLRELELADDV-----DLASIAENMEGYSGADITNVCRDASLMAMRRRI 257 Query: 77 FNMDPKKGIQFLIENDLLQSSPED 100 + P++ E + ++ ED Sbjct: 258 EGLTPEEIRNLSKEEMHMPTTMED 281 >3PVW-A nrPDB Length = 695 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 27/161 (16%), Positives = 56/161 (34%), Gaps = 30/161 (18%) Query: 241 ESIKNEPFKIPEDDGNDLTHTFFNPD--REGWLLKLGG-RVKTWKRRWFILTDNCLYYFE 297 + ++ + G++ + D G++ K+G + W+RR+F L N L + Sbjct: 534 DRLEARKKTKNKQLGHEEDYA-LGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEW-- 590 Query: 298 YTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVV 357 + P+ ++ +E + E ++ C L K V Sbjct: 591 RGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFV------------------- 631 Query: 358 YRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANK 398 + S E +W K ++ + L R ++ NK Sbjct: 632 --LQCDSDPELVQWKKELRDAYREA---QQLVQRVPKMKNK 667 >1EJI-A nrPDB Length = 478 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 32/83 (38%), Gaps = 12/83 (14%) Query: 84 GIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELH--EFA 141 G L LL+ + VA F+++G L + + L+ F E + Sbjct: 398 GTPALTSRGLLEEDFQKVAHFIHRGIELTLQI------QSHMATKATLKEFKEKLAGDEK 451 Query: 142 DLNLVQALRQ----FLWSFRLPG 160 + V LR+ F +F LPG Sbjct: 452 IQSAVATLREEVENFASNFSLPG 474 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.131 0.339 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,258,118 Number of Sequences: 36641 Number of extensions: 629348 Number of successful extensions: 2203 Number of sequences better than 10.0: 71 Number of HSP's better than 10.0 without gapping: 81 Number of HSP's successfully gapped in prelim test: 50 Number of HSP's that attempted gapping in prelim test: 2032 Number of HSP's gapped (non-prelim): 141 length of query: 399 length of database: 10,336,785 effective HSP length: 99 effective length of query: 300 effective length of database: 6,709,326 effective search space: 2012797800 effective search space used: 2012797800 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.7 bits)