BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O00764 (312 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2F7K-A nrPDB 648 0.0 1YGJ-A nrPDB 579 e-166 3ZS7-A nrPDB 198 2e-51 5B6A-A nrPDB 138 3e-33 5TRW-A nrPDB 130 1e-30 3PZS-A nrPDB 129 2e-30 5TQI-A nrPDB 125 3e-29 1TD2-A nrPDB 119 2e-27 4S1M-A nrPDB 117 9e-27 5ZWB-B nrPDB 90 1e-18 2DDM-A nrPDB 90 1e-18 3MBJ-A nrPDB 58 5e-09 4JJP-A nrPDB 54 8e-08 1RK2-A nrPDB 45 3e-05 2I5B-A nrPDB 45 4e-05 4X8F-A nrPDB 41 6e-04 3RY7-A nrPDB 41 6e-04 1UB0-A nrPDB 40 0.001 3HYO-A nrPDB 37 0.007 3RM5-A nrPDB 37 0.008 5ZWY-A nrPDB 37 0.015 5C40-A nrPDB 36 0.024 4C5N-A nrPDB 35 0.053 4YL5-A nrPDB 34 0.085 2V5J-A nrPDB 32 0.41 4B5T-A nrPDB 32 0.42 6OJM-A nrPDB 31 0.57 3Q7I-A nrPDB 28 3.7 3T8B-A nrPDB 28 4.1 5ZIB-A nrPDB 28 5.5 3RMJ-A nrPDB 28 5.5 4YKA-A nrPDB 28 5.6 5ZIC-A nrPDB 28 6.5 >2F7K-A nrPDB Length = 327 Score = 648 bits (1671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/312 (100%), Positives = 312/312 (100%) Query: 1 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD Sbjct: 16 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 75 Query: 61 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 120 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW Sbjct: 76 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 135 Query: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP Sbjct: 136 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 195 Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM Sbjct: 196 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 255 Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 300 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI Sbjct: 256 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 315 Query: 301 EDPEIVVQATVL 312 EDPEIVVQATVL Sbjct: 316 EDPEIVVQATVL 327 >1YGJ-A nrPDB Length = 312 Score = 579 bits (1492), Expect = e-166, Method: Compositional matrix adjust. Identities = 271/312 (86%), Positives = 300/312 (96%) Query: 1 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60 MEEECRVLSIQSHV+RGYVGNRAATFPLQVLGFE+DAVNSVQFSNHTGY+HWKGQVLNSD Sbjct: 1 MEEECRVLSIQSHVVRGYVGNRAATFPLQVLGFEVDAVNSVQFSNHTGYSHWKGQVLNSD 60 Query: 61 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 120 ELQELY+GL+LN++N+YDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPV+GD+ Sbjct: 61 ELQELYDGLKLNHVNQYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVMGDQR 120 Query: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180 +GEG+MYVP+DLLPVY+EKVVP+ADIITPNQFEAELL+GRKIHSQEEAL VMDMLHSMGP Sbjct: 121 NGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSMGP 180 Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240 DTVVITSS+L SP+GS+YL+ LGSQR R P GSVV +RIRM++ KVDAVFVGTGDLFAAM Sbjct: 181 DTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAVFVGTGDLFAAM 240 Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 300 LLAWTHKHPNNLKVACEKTVS +HHVLQRTI+CAKA++GEGV+PSP QLELRMVQSK+DI Sbjct: 241 LLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELRMVQSKKDI 300 Query: 301 EDPEIVVQATVL 312 E PEIVVQATVL Sbjct: 301 ESPEIVVQATVL 312 >3ZS7-A nrPDB Length = 300 Score = 198 bits (504), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 119/309 (38%), Positives = 181/309 (58%), Gaps = 22/309 (7%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 E VLSIQS V GYVGN+AATFPLQ+ GF++D +N+V SNH+GY +G ++ E Sbjct: 3 EKTVLSIQSFVTHGYVGNKAATFPLQLHGFDVDGINTVCLSNHSGYPVIRGHRMSLQEYD 62 Query: 64 ELYEGLRLNN-MNKYDYVLTGYTRDKSFLAMVVDIVQELKQ----QNPRLVYVCDPVLGD 118 EL EG+R NN ++ Y Y+LTGY + + + D ++E+++ ++ +L ++CDPV+GD Sbjct: 63 ELMEGVRANNFLSNYRYILTGYINNVDIIGRIRDTLKEVRELREKEDKKLTFICDPVMGD 122 Query: 119 KWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSM 178 +G MY +++L Y+E +VPLADI+TPN FEA LLSG ++ A+ D H+ Sbjct: 123 ----DGIMYCKKEVLDAYRE-LVPLADIVTPNYFEASLLSGVTVNDLSSAILAADWFHNC 177 Query: 179 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFA 238 G V+I S + +L L S + + A + R + + + GTGD+FA Sbjct: 178 GVAHVIIKS--FREQENPTHLRFLYSVKEGSEAA---VRRFSGVVPYHEGRYTGTGDVFA 232 Query: 239 AMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKR 298 A LLA++H HP + VA K+++ VLQ I + + G+G + S ELR+V S + Sbjct: 233 ACLLAFSHSHP--MDVAIGKSMA----VLQELIIATRKEGGDG-KSSLKSRELRVVASPQ 285 Query: 299 DIEDPEIVV 307 + P VV Sbjct: 286 VVLQPSTVV 294 >5B6A-A nrPDB Length = 288 Score = 138 bits (348), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 95/317 (29%), Positives = 155/317 (48%), Gaps = 34/317 (10%) Query: 1 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60 M +L+IQSHV+ G+ GN AA FP+Q +G + +N+VQFSNHT Y W GQVL + Sbjct: 1 MPRTPHLLAIQSHVVFGHAGNAAAVFPMQRIGINVWPLNTVQFSNHTQYGRWTGQVLPPE 60 Query: 61 ELQELYEGLR-LNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDK 119 ++ L +G+ + + D VL+GY + ++D+V +KQ NPR +Y+CDPV+G Sbjct: 61 QIPALVDGIAGIGELGNCDAVLSGYLGSAAQGRAILDVVARIKQANPRALYLCDPVMGHP 120 Query: 120 WDGEGSMYVPE--DLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHS 177 +G + PE D L E+ +AD + PNQ E + R+ +S + + + L + Sbjct: 121 --EKGCIVAPEVSDFL---LEEAAAVADYLCPNQLELDSFCDRQPNSLADCVEMARSLLA 175 Query: 178 MGPDTVVITSSDLPSPQGSNY--LIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGD 235 GP +++ + P G + L+V Q ++R + + VG GD Sbjct: 176 RGPRAILVKHLNYPGKAGDTFEMLLVAADQAWH-------LQRPLLAFPRQP---VGVGD 225 Query: 236 LFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQ 295 L + + L+ ++L+ A E T + +H VL T C EL +V+ Sbjct: 226 LASGLFLSRLLLG-DDLRNAFEFTGAAVHEVLLETQACGS-------------YELELVR 271 Query: 296 SKRDIEDPEIVVQATVL 312 ++ I P + A L Sbjct: 272 AQDRIAHPRVRFDAVRL 288 >5TRW-A nrPDB Length = 296 Score = 130 bits (326), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 94/300 (31%), Positives = 155/300 (51%), Gaps = 31/300 (10%) Query: 7 VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELY 66 VLSIQSHV+ G+ GN AA FP++ LG + +N+VQFSNHT Y HW G +++ ++ EL Sbjct: 13 VLSIQSHVVFGHAGNSAAVFPMRRLGVNVWPLNTVQFSNHTQYGHWTGGAIDATQMVELV 72 Query: 67 EGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGS 125 +G+ + + + D VL+GY V++IV+ +K NPR Y CDPV+G + Sbjct: 73 DGIGAIGMLPRCDAVLSGYLGTPEQAQSVLEIVKAVKAANPRAWYFCDPVMGAVSGCKVE 132 Query: 126 MYVPEDLLPVYKEKVVP-LADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVV 184 + E L+ + +P +AD + PN E + L GR+I + EEA+ L + GP V+ Sbjct: 133 PGIQEFLV-----RTMPGVADAMAPNHTELQRLVGREIETLEEAVTACRELIARGPKLVL 187 Query: 185 ITS-SDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLA 243 + D SP ++V+ ++R + R VG GDL +A+ +A Sbjct: 188 VKHLLDRNSPADRFNMLVV-TEREAWMGQRPLYPFARQP--------VGVGDLTSAVFVA 238 Query: 244 WTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDP 303 T ++++ A E T++ ++ V++ T Q + EL +V ++ +I P Sbjct: 239 RTLLG-DSIRAAFEHTLAAVNAVVKATWQAGR-------------YELELVAAQSEIAQP 284 >3PZS-A nrPDB Length = 289 Score = 129 bits (324), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 65/180 (36%), Positives = 105/180 (58%), Gaps = 4/180 (2%) Query: 7 VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELY 66 +LSIQSHV+ G+ GN AA FP++ +G + +N+VQFSNHT Y HW G V+ + L ++ Sbjct: 7 ILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIV 66 Query: 67 EGLR-LNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGS 125 +G+ ++ + D VL+GY + ++ V ++KQ NP Y CDPV+G E Sbjct: 67 QGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHP---EKG 123 Query: 126 MYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVI 185 V + + + +P +D+I PN E E LSG ++ + E+A++V L + GP V++ Sbjct: 124 CIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLV 183 >5TQI-A nrPDB Length = 294 Score = 125 bits (314), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 87/271 (32%), Positives = 143/271 (52%), Gaps = 26/271 (9%) Query: 7 VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELY 66 VLSIQSHVI G+ GN AA FP+Q LG + +N+VQ SNH Y HW G +++ ++++L Sbjct: 12 VLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLV 71 Query: 67 EGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGS 125 +G+ + + + D VL+G+ + V+IV+ +K NP Y CDP +G G Sbjct: 72 DGIAAIGALKRCDAVLSGFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQT----GG 127 Query: 126 MYVPEDLLPVYKEKVV----PLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPD 181 + PE P +E +V LAD ++PN E + L+GR+I + EA+ L + GP Sbjct: 128 IR-PE---PGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPK 183 Query: 182 TVVITS-SDLPSPQGS-NYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAA 239 +++ D SP N L V ++ + + +R + VG GDL +A Sbjct: 184 IILVKHLHDRNSPADRFNMLAVTETE-------AWIGQRPLYAFPRHP---VGVGDLTSA 233 Query: 240 MLLAWTHKHPNNLKVACEKTVSTLHHVLQRT 270 + +A ++++ A E T++ +H V++ T Sbjct: 234 IFVA-RRLRGDSVRAAFEHTLAAVHAVVKAT 263 >1TD2-A nrPDB Length = 287 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 64/180 (35%), Positives = 101/180 (56%), Gaps = 4/180 (2%) Query: 7 VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELY 66 +L+IQSHV+ G+ GN AA FP++ LG + +N+VQFSNHT Y W G V+ L E+ Sbjct: 5 ILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTEIV 64 Query: 67 EGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGS 125 +G+ ++ ++ D VL+GY ++ IV+++K NP+ Y CDPV+G E Sbjct: 65 QGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHP---EKG 121 Query: 126 MYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVI 185 V + + +P +DII PN E E+L +++ EEA+ L + GP V++ Sbjct: 122 CIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLV 181 >4S1M-A nrPDB Length = 287 Score = 117 bits (292), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 76/272 (27%), Positives = 141/272 (51%), Gaps = 20/272 (7%) Query: 6 RVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQEL 65 +VL+I S+V G+VGNR L + V + +NHTGY G + ++ + Sbjct: 4 KVLTISSYVCSGFVGNRCGMIILDSFQIQSIFVLTTHLANHTGYPVVGGSGVLLNDFISI 63 Query: 66 YEGLRLNNMNK-YDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEG 124 + L +N+++K ++++TGY + ++ V+ +K N ++ ++CDP+LGD G Sbjct: 64 MDSLEVNHLDKDIEFLVTGYFPSSDLVYETINRVKRIKD-NKKVYFLCDPILGDN----G 118 Query: 125 SMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVV 184 MY ++ KE ++ ADIITPN E L+G +++S EA++ +LH G ++ Sbjct: 119 KMYTKSEVQDSMKE-LIKYADIITPNATELSFLTGLEVNSVSEAIKACHILHEQGIPVIL 177 Query: 185 ITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAW 244 +TS +G++ +++ + N + + I +++ F G GD +LL+W Sbjct: 178 VTS----IKEGNDIILLCSFKDTLNN------KNFTIKIPRIEGDFTGVGDTLTYILLSW 227 Query: 245 THKH-PNNLKVACEKTVSTLHHVLQRTIQCAK 275 K P L+ A + +STL +L+ T+ A+ Sbjct: 228 IIKGIP--LEHAVNRAISTLQTILRNTVGTAE 257 >5ZWB-B nrPDB Length = 296 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/269 (25%), Positives = 121/269 (44%), Gaps = 17/269 (6%) Query: 7 VLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELY 66 ++++QS V+ G VGN A ++ G + AV +V FSN Y + G ++ ++ Sbjct: 23 IVAVQSQVVYGSVGNSIAVPAIKAQGLRVTAVPTVLFSNTPHYKTFYGGIIPAEWFAGYL 82 Query: 67 EGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGS 125 L + + + + TGY + ++ + ++ +P + + DPV+GD G Sbjct: 83 TALNERDALRELKAITTGYMGSADQIVLLSKWLMAIRASHPEVCILVDPVIGDTDSG--- 139 Query: 126 MYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVI 185 MYV ++ Y+ ++P A +TPN FE E+LSG+ + EEA+ L S VVI Sbjct: 140 MYVQAEIPQAYRTHLLPQAQGLTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVI 199 Query: 186 TSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWT 245 TS+ G + + + R+ +++ GTGDLF A L++ Sbjct: 200 TSAP-----GESLETITVAVVTAQVVEVFAHPRVATELK-------GTGDLFCAELVSGI 247 Query: 246 HKHPNNLKVACEKTVSTLHHVLQRTIQCA 274 + L A + + V+ T QC Sbjct: 248 VQG-KKLTTAAKDAAQRVLEVMTWTQQCG 275 >2DDM-A nrPDB Length = 283 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 66/241 (27%), Positives = 118/241 (48%), Gaps = 15/241 (6%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 + ++++QS V+ G VGN A ++ G + AV +V SN Y + G + + Sbjct: 15 QADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFS 74 Query: 64 ELYEGLR-LNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDG 122 L+ + + + V TGY S + ++ + + L++ +P L+ + DPV+GD G Sbjct: 75 GYLRALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSG 134 Query: 123 EGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT 182 +YV DL Y++ ++PLA ITPN FE E+L+G+ + A+ L S Sbjct: 135 ---IYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKW 191 Query: 183 VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242 VV+TS+ ++V+ + + + R++ D++ GTGDLF A L+ Sbjct: 192 VVVTSASGNEENQEMQVVVVTA----DSVNVISHSRVKTDLK-------GTGDLFCAQLI 240 Query: 243 A 243 + Sbjct: 241 S 241 >3MBJ-A nrPDB Length = 291 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 60/218 (27%), Positives = 100/218 (45%), Gaps = 21/218 (9%) Query: 28 LQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRD 87 L +GF++ + + SNHT Y + L + + + E +L ++D + TGY Sbjct: 31 LSSMGFQVCPLPTAVLSNHTQYPGFSFLDLTDEMPKIIAEWKKLEV--QFDAIYTGYLGS 88 Query: 88 KSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEK-VVPLADI 146 + +V D +++ +Q P + V DPVLGD G +Y D+ V + + ++ AD+ Sbjct: 89 PRQIQIVSDFIKDFRQ--PDSLIVADPVLGDN----GRLYTNFDMEMVKEMRHLITKADV 142 Query: 147 ITPNQFEAELL--SGRKIHSQEEALR-VMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLG 203 ITPN E L K S +E L+ + +L GP V+ITS +P + V Sbjct: 143 ITPNLTELFYLLDEPYKADSTDEELKEYLRLLSDKGPQVVIITS--VPVHDEPHKTSVYA 200 Query: 204 SQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAML 241 R+ N V + A + GTGD F +++ Sbjct: 201 YNRQGNRYWKVTCPYL-------PAHYPGTGDTFTSVI 231 >4JJP-A nrPDB Length = 267 Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 44/132 (33%), Positives = 70/132 (53%), Gaps = 19/132 (14%) Query: 93 MVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVV----PLADIIT 148 ++++IV+ LK+ NP+ + V DPV+ K Y+ L P KE ++ PLA IIT Sbjct: 91 IILEIVENLKKYNPKYL-VVDPVMISK----SGYYL---LKPEAKENLIKYLIPLAYIIT 142 Query: 149 PNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQ-----GSNYLIVLG 203 PN EAE ++G KIH+ ++ RV + + +GP V++ L G N V Sbjct: 143 PNIPEAEEITGIKIHNVDDMKRVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYK 202 Query: 204 SQR--RRNPAGS 213 S+R ++N G+ Sbjct: 203 SERIDKKNTHGT 214 >1RK2-A nrPDB Length = 309 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 20/114 (17%) Query: 138 EKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSN 197 ++++ L DIITPN+ EAE L+G ++ + E+A + +LH G TV+IT Sbjct: 175 DELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLIT----------- 223 Query: 198 YLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLF-AAMLLAWTHKHP 249 LGS R SV E R+ +V AV + GD F A++ A + P Sbjct: 224 ----LGS---RGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKP 270 >2I5B-A nrPDB Length = 271 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 20/142 (14%) Query: 52 WKGQVLNSD------ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQN 105 W QV D +L + +G+ ++ M TG + + ++E + +N Sbjct: 50 WNHQVFPIDTDTIRAQLATITDGIGVDAMK------TGMLPTVDIIELAAKTIKEKQLKN 103 Query: 106 PRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGR-KIHS 164 V DPV+ K G + PE + +E++ PLA +ITPN FEA LSG ++ + Sbjct: 104 ----VVIDPVMVCK--GANEVLYPEHAQAL-REQLAPLATVITPNLFEASQLSGMDELKT 156 Query: 165 QEEALRVMDMLHSMGPDTVVIT 186 ++ + +H++G VVIT Sbjct: 157 VDDMIEAAKKIHALGAQYVVIT 178 >4X8F-A nrPDB Length = 309 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 31/49 (63%) Query: 138 EKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVIT 186 ++++ D+ITPN+ EAE+L+G ++ A + D LH G + V+IT Sbjct: 175 DELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIIT 223 >3RY7-A nrPDB Length = 304 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 22/130 (16%) Query: 129 PEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSS 188 P LP +++ L DII PN+ EAELLSG K+ +++ + S+G TV+IT Sbjct: 168 PAKALP---NELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLIT-- 222 Query: 189 DLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLFAAMLLAWTHK 247 QG+ + SQ ++ KV+A+ GD F ++ +K Sbjct: 223 --LGKQGTYFATKNQSQ--------------HIEAYKVNAIDTTAAGDTFIGAFVSRLNK 266 Query: 248 HPNNLKVACE 257 +NL A + Sbjct: 267 SQDNLADAID 276 >1UB0-A nrPDB Length = 258 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 37/69 (53%) Query: 139 KVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNY 198 ++ PLAD++TPN+ EAE L GR I + +EA L ++GP V++ L + + Sbjct: 126 RLFPLADLVTPNRLEAEALLGRPIRTLKEAEEAAKALLALGPKAVLLKGGHLEGEEAVDL 185 Query: 199 LIVLGSQRR 207 L G R Sbjct: 186 LATRGGVLR 194 >3HYO-A nrPDB Length = 282 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 58/232 (25%), Positives = 95/232 (40%), Gaps = 55/232 (23%) Query: 28 LQVLGFEIDAVNSVQFSNHT-GY--------AHWKGQVLNSDELQELYEGLRLNNMNKYD 78 L + +++ A+ + S HT GY + W QV +L+ +D Sbjct: 27 LTAMQYDVAALPTSLLSTHTSGYGTPAVVDLSTWLPQVFAHWTRAQLH----------FD 76 Query: 79 YVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMY--VPEDLLPVY 136 L GY +A+ I L+QQ L+ V DPVLGD G +Y +D + Sbjct: 77 QALIGYVGS---VALCQQITTYLEQQTLSLL-VVDPVLGDL----GQLYQGFDQDYVAAM 128 Query: 137 KEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQG- 195 ++ ++ AD+I PN EA LL+G + + PD VI LP+ Q Sbjct: 129 RQ-LIQQADVILPNTTEAALLTGAP--------------YQVTPDLEVI----LPALQAQ 169 Query: 196 --SNYLIVLGSQRRRNPAGSVVMERI----RMDIRKVDAVFVGTGDLFAAML 241 + V+ +R + G ++ R++ + GTGD AA++ Sbjct: 170 LKTGAHAVITDVQRADQIGCAWLDEAGHVQYCGARRLPGHYNGTGDTLAAVI 221 >3RM5-A nrPDB Length = 550 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 11/86 (12%) Query: 92 AMVVDIVQE----LKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADII 147 A ++++ E L + P+LV DPVL GS +D++ + EKV P ADI+ Sbjct: 102 AAAIEVLHEKLLQLGENRPKLV--VDPVLVAT---SGSSLAGKDIVSLITEKVAPFADIL 156 Query: 148 TPNQFEAELLSG--RKIHSQEEALRV 171 TPN E L G RK++ ++ ++ Sbjct: 157 TPNIPECYKLLGEERKVNGLQDIFQI 182 >5ZWY-A nrPDB Length = 349 Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust. Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 19/119 (15%) Query: 141 VPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLI 200 +P + PN+ EA L++G K+ E A + L +G VVIT L Sbjct: 220 LPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVIT------------LG 267 Query: 201 VLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLFAAMLLAWTHKHPNNLKVACEK 258 G N A E + + + V AV G GD F ++ + + N L+ AC++ Sbjct: 268 AAGFVLSENGA-----EPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLE-ACKR 320 >5C40-A nrPDB Length = 330 Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust. Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 20/161 (12%) Query: 119 KWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSM 178 + G +++ P + + L+D+ N+ EAE+L+G + S +A +L Sbjct: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227 Query: 179 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLF 237 G V+IT G+ +VL SQ P + KV AV G GD F Sbjct: 228 GCQVVIIT-------LGAEGCVVL-SQTEPEPK--------HIPTEKVKAVDTTGAGDSF 271 Query: 238 AAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQA 278 L + +PN ++ E ++ + + ++Q A Q+ Sbjct: 272 VGALAFYLAYYPN---LSLEDMLNRSNFIAAVSVQAAGTQS 309 >4C5N-A nrPDB Length = 276 Score = 34.7 bits (78), Expect = 0.053, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 4/77 (5%) Query: 110 YVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSG-RKIHSQEEA 168 +V DPV+ K GE + P + + K ++P A ++TPN FEA LSG K++S E+ Sbjct: 102 FVVDPVMVCK--GEDEVLNPGNTEAMIK-YLLPKATVVTPNLFEAGQLSGLGKLNSIEDM 158 Query: 169 LRVMDMLHSMGPDTVVI 185 + ++ G V+I Sbjct: 159 KKAATIIFDKGAQHVII 175 >4YL5-A nrPDB Length = 263 Score = 33.9 bits (76), Expect = 0.085, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 95 VDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEA 154 + + E + +P YV DPVL + GS+ L+ + E ++PLA +ITPN E Sbjct: 94 IAALAEFLRAHPDYQYVLDPVL--VANSGGSLGDQATLVKAFVE-LIPLATLITPNTVEL 150 Query: 155 ELLSG 159 L+G Sbjct: 151 RALTG 155 >2V5J-A nrPDB Length = 287 Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 221 MDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTV 260 +D+ VD VF+G DL A M A +HP ++ A E+ + Sbjct: 186 LDVEGVDGVFIGPADLSADMGYAGNPQHP-EVQAAIEQAI 224 >4B5T-A nrPDB Length = 251 Score = 31.6 bits (70), Expect = 0.42, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 221 MDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTV 260 +D+ VD VF+G DL A M A +HP ++ A E+ + Sbjct: 161 LDVEGVDGVFIGPADLSADMGYAGNPQHP-EVQAAIEQAI 199 >6OJM-A nrPDB Length = 286 Score = 31.2 bits (69), Expect = 0.57, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Query: 183 VVITSSDLPSPQGSNYLIVLGS-QRRRNPAGSVVME-RIRMDIRKVDAVFVGTGDLFAAM 240 VV+ S + PSP+ + G Q+ R G V + R R++I +V + + A+ Sbjct: 66 VVLLSGEGPSPKDGGWAFCSGGDQKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAV 125 Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVL 267 + W ++L V C+ T+++ H + Sbjct: 126 VPGWAVGGGHSLHVVCDLTLASKEHAI 152 >3Q7I-A nrPDB Length = 543 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 38/66 (57%), Gaps = 4/66 (6%) Query: 60 DELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVD---IVQELKQQNPRLVYVCDPVL 116 D++++++ G ++N+ ++ VL RD S ++VD I QE+ ++ R+ + + V+ Sbjct: 70 DKIKQMFNGAKINS-TEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVV 128 Query: 117 GDKWDG 122 +W G Sbjct: 129 SGRWRG 134 >3T8B-A nrPDB Length = 334 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 14/121 (11%) Query: 155 ELLSGRKIHSQEEALRVMDMLHSMGPDT-VVITSSDLPSPQGSNYLIVLGS-QRRRNPAG 212 E+ + + H+ +E RV+D M PD VV+ + + PSP+ + G QR R +G Sbjct: 76 EVRNAFRPHTVDELYRVLDHAR-MSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSG 134 Query: 213 ----------SVVMERI-RMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVS 261 +V + R R+ I +V + + ++ W ++L V C+ T++ Sbjct: 135 YQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLA 194 Query: 262 T 262 + Sbjct: 195 S 195 >5ZIB-A nrPDB Length = 626 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 18/85 (21%) Query: 35 IDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMV 94 +D+ + NH YA KG + + LN Y + +T D SFL V Sbjct: 262 LDSFGTEPEFNHANYAQSKGH-------KTPWGKWNLNPQQFY--TMFPHTPDNSFLGFV 312 Query: 95 V-------DI--VQELKQQNPRLVY 110 V DI + E+K+QN LVY Sbjct: 313 VEQHLNSSDIHHINEIKRQNQSLVY 337 >3RMJ-A nrPDB Length = 370 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 13/73 (17%) Query: 216 MERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAK 275 +E++ +DI + GD A +A K + TV +L ++R I+ Sbjct: 43 LEKLGVDIIEAGFAAASPGDFEAVNAIA---------KTITKSTVCSLSRAIERDIR--- 90 Query: 276 AQAGEGVRPSPMQ 288 QAGE V P+P + Sbjct: 91 -QAGEAVAPAPKK 102 >4YKA-A nrPDB Length = 103 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 24/52 (46%) Query: 139 KVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDL 190 KV+ L D TP +F +L S++ RVM H G VV+ D+ Sbjct: 25 KVMLLNDDYTPREFVTVVLKAVFRMSEDTGRRVMMTAHRFGSAVVVVCERDI 76 >5ZIC-A nrPDB Length = 523 Score = 27.7 bits (60), Expect = 6.5, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 20/86 (23%) Query: 35 IDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYD-YVLTGYTRDKSFLAM 93 +D+ + NH YA KG + N+N Y + +T D SFL Sbjct: 159 LDSFGTEPEFNHANYAQSKGHKTPWGKW----------NLNPQQFYTMFPHTPDNSFLGF 208 Query: 94 VV-------DI--VQELKQQNPRLVY 110 VV DI + E+K+QN LVY Sbjct: 209 VVEQHLNSSDIHHINEIKRQNQSLVY 234 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2F7K-A nrPDB 428 e-120 1YGJ-A nrPDB 420 e-118 5B6A-A nrPDB 345 2e-95 5TRW-A nrPDB 318 2e-87 3ZS7-A nrPDB 305 1e-83 3PZS-A nrPDB 302 9e-83 5TQI-A nrPDB 302 2e-82 1TD2-A nrPDB 288 2e-78 2DDM-A nrPDB 260 6e-70 5ZWB-B nrPDB 256 1e-68 4S1M-A nrPDB 245 2e-65 3MBJ-A nrPDB 204 4e-53 2I5B-A nrPDB 115 2e-26 4JJP-A nrPDB 111 3e-25 3RY7-A nrPDB 89 3e-18 1RK2-A nrPDB 81 6e-16 4X8F-A nrPDB 75 5e-14 1UB0-A nrPDB 66 2e-11 Sequences not found previously or not previously below threshold: 4C5N-A nrPDB 84 5e-17 4YL5-A nrPDB 83 1e-16 3HYO-A nrPDB 76 1e-14 1JXH-A nrPDB 71 7e-13 3RM5-A nrPDB 58 5e-09 5C40-A nrPDB 53 2e-07 5ZWY-A nrPDB 52 3e-07 6ILS-A nrPDB 52 3e-07 1VM7-A nrPDB 48 5e-06 3H49-A nrPDB 47 1e-05 2ABQ-A nrPDB 47 1e-05 2JG5-A nrPDB 44 7e-05 3KZH-A nrPDB 44 9e-05 3KD6-A nrPDB 40 0.001 3LOO-A nrPDB 38 0.006 5EYN-A nrPDB 37 0.008 4WJM-A nrPDB 36 0.026 5KB6-A nrPDB 36 0.029 3IQ0-A nrPDB 36 0.033 3JUL-A nrPDB 34 0.073 1V1S-A nrPDB 34 0.080 4N08-A nrPDB 34 0.090 2I6B-A nrPDB 32 0.32 3I3Y-A nrPDB 32 0.39 5HXD-A nrPDB 31 0.67 2AFB-A nrPDB 31 0.74 3LFH-A nrPDB 29 1.9 3N1C-A nrPDB 29 2.4 2B20-A nrPDB 29 4.0 >2F7K-A nrPDB Length = 327 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 312/312 (100%), Positives = 312/312 (100%) Query: 1 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD Sbjct: 16 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 75 Query: 61 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 120 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW Sbjct: 76 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 135 Query: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP Sbjct: 136 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 195 Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM Sbjct: 196 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 255 Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 300 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI Sbjct: 256 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 315 Query: 301 EDPEIVVQATVL 312 EDPEIVVQATVL Sbjct: 316 EDPEIVVQATVL 327 >1YGJ-A nrPDB Length = 312 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 271/312 (86%), Positives = 300/312 (96%) Query: 1 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60 MEEECRVLSIQSHV+RGYVGNRAATFPLQVLGFE+DAVNSVQFSNHTGY+HWKGQVLNSD Sbjct: 1 MEEECRVLSIQSHVVRGYVGNRAATFPLQVLGFEVDAVNSVQFSNHTGYSHWKGQVLNSD 60 Query: 61 ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 120 ELQELY+GL+LN++N+YDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPV+GD+ Sbjct: 61 ELQELYDGLKLNHVNQYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVMGDQR 120 Query: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180 +GEG+MYVP+DLLPVY+EKVVP+ADIITPNQFEAELL+GRKIHSQEEAL VMDMLHSMGP Sbjct: 121 NGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSMGP 180 Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240 DTVVITSS+L SP+GS+YL+ LGSQR R P GSVV +RIRM++ KVDAVFVGTGDLFAAM Sbjct: 181 DTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAVFVGTGDLFAAM 240 Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 300 LLAWTHKHPNNLKVACEKTVS +HHVLQRTI+CAKA++GEGV+PSP QLELRMVQSK+DI Sbjct: 241 LLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELRMVQSKKDI 300 Query: 301 EDPEIVVQATVL 312 E PEIVVQATVL Sbjct: 301 ESPEIVVQATVL 312 >5B6A-A nrPDB Length = 288 Score = 345 bits (884), Expect = 2e-95, Method: Composition-based stats. Identities = 90/313 (28%), Positives = 153/313 (48%), Gaps = 26/313 (8%) Query: 1 MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60 M +L+IQSHV+ G+ GN AA FP+Q +G + +N+VQFSNHT Y W GQVL + Sbjct: 1 MPRTPHLLAIQSHVVFGHAGNAAAVFPMQRIGINVWPLNTVQFSNHTQYGRWTGQVLPPE 60 Query: 61 ELQELYEGLR-LNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDK 119 ++ L +G+ + + D VL+GY + ++D+V +KQ NPR +Y+CDPV+G Sbjct: 61 QIPALVDGIAGIGELGNCDAVLSGYLGSAAQGRAILDVVARIKQANPRALYLCDPVMGHP 120 Query: 120 WDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMG 179 E V ++ E+ +AD + PNQ E + R+ +S + + + L + G Sbjct: 121 ---EKGCIVAPEVSDFLLEEAAAVADYLCPNQLELDSFCDRQPNSLADCVEMARSLLARG 177 Query: 180 PDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAA 239 P +++ + P G + ++L + + ++R + + VG GDL + Sbjct: 178 PRAILVKHLNYPGKAGDTFEMLLVAADQAWH-----LQRPLLAFPRQP---VGVGDLASG 229 Query: 240 MLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRD 299 + L+ ++L+ A E T + +H VL T C EL +V+++ Sbjct: 230 LFLSRLLLG-DDLRNAFEFTGAAVHEVLLETQACG-------------SYELELVRAQDR 275 Query: 300 IEDPEIVVQATVL 312 I P + A L Sbjct: 276 IAHPRVRFDAVRL 288 >5TRW-A nrPDB Length = 296 Score = 318 bits (814), Expect = 2e-87, Method: Composition-based stats. Identities = 93/308 (30%), Positives = 152/308 (49%), Gaps = 29/308 (9%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 VLSIQSHV+ G+ GN AA FP++ LG + +N+VQFSNHT Y HW G +++ ++ Sbjct: 10 TKNVLSIQSHVVFGHAGNSAAVFPMRRLGVNVWPLNTVQFSNHTQYGHWTGGAIDATQMV 69 Query: 64 ELYEGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDG 122 EL +G+ + + + D VL+GY V++IV+ +K NPR Y CDPV+G Sbjct: 70 ELVDGIGAIGMLPRCDAVLSGYLGTPEQAQSVLEIVKAVKAANPRAWYFCDPVMGAVSGC 129 Query: 123 EGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT 182 + V + + +AD + PN E + L GR+I + EEA+ L + GP Sbjct: 130 K----VEPGIQEFLVRTMPGVADAMAPNHTELQRLVGREIETLEEAVTACRELIARGPKL 185 Query: 183 VVITS-SDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAML 241 V++ D SP ++V+ ++R + R VG GDL +A+ Sbjct: 186 VLVKHLLDRNSPADRFNMLVV-TEREAWMGQRPLYPFARQP--------VGVGDLTSAVF 236 Query: 242 LAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIE 301 +A T ++++ A E T++ ++ V++ T Q + EL +V ++ +I Sbjct: 237 VARTLLG-DSIRAAFEHTLAAVNAVVKATWQAGR-------------YELELVAAQSEIA 282 Query: 302 DPEIVVQA 309 P A Sbjct: 283 QPREWFDA 290 >3ZS7-A nrPDB Length = 300 Score = 305 bits (782), Expect = 1e-83, Method: Composition-based stats. Identities = 119/310 (38%), Positives = 180/310 (58%), Gaps = 22/310 (7%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 E VLSIQS V GYVGN+AATFPLQ+ GF++D +N+V SNH+GY +G ++ E Sbjct: 3 EKTVLSIQSFVTHGYVGNKAATFPLQLHGFDVDGINTVCLSNHSGYPVIRGHRMSLQEYD 62 Query: 64 ELYEGLRLNN-MNKYDYVLTGYTRDKSFLAMVVDIVQELK----QQNPRLVYVCDPVLGD 118 EL EG+R NN ++ Y Y+LTGY + + + D ++E++ +++ +L ++CDPV+GD Sbjct: 63 ELMEGVRANNFLSNYRYILTGYINNVDIIGRIRDTLKEVRELREKEDKKLTFICDPVMGD 122 Query: 119 KWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSM 178 +G MY +++L Y+E +VPLADI+TPN FEA LLSG ++ A+ D H+ Sbjct: 123 ----DGIMYCKKEVLDAYRE-LVPLADIVTPNYFEASLLSGVTVNDLSSAILAADWFHNC 177 Query: 179 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFA 238 G V+I S + +L L S + + A R + + + GTGD+FA Sbjct: 178 GVAHVIIKS--FREQENPTHLRFLYSVKEGSEAAV---RRFSGVVPYHEGRYTGTGDVFA 232 Query: 239 AMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKR 298 A LLA++H HP + VA K+++ VLQ I + + G+G + S ELR+V S + Sbjct: 233 ACLLAFSHSHP--MDVAIGKSMA----VLQELIIATRKEGGDG-KSSLKSRELRVVASPQ 285 Query: 299 DIEDPEIVVQ 308 + P VV Sbjct: 286 VVLQPSTVVD 295 >3PZS-A nrPDB Length = 289 Score = 302 bits (774), Expect = 9e-83, Method: Composition-based stats. Identities = 86/309 (27%), Positives = 148/309 (47%), Gaps = 25/309 (8%) Query: 5 CRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQE 64 +LSIQSHV+ G+ GN AA FP++ +G + +N+VQFSNHT Y HW G V+ + L + Sbjct: 5 KNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTD 64 Query: 65 LYEGLR-LNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGE 123 + +G+ ++ + D VL+GY + ++ V ++KQ NP Y CDPV+G E Sbjct: 65 IVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHP---E 121 Query: 124 GSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTV 183 V + + + +P +D+I PN E E LSG ++ + E+A++V L + GP V Sbjct: 122 KGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVV 181 Query: 184 VITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLA 243 ++ + ++L + +++ ++ VG GDL + +LL Sbjct: 182 LVKHLSRAGYHADCFEMLLVTADDAWHICRPLVDF----GKRQP---VGVGDLTSGLLLV 234 Query: 244 WTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDP 303 K L A E + ++ V+ +T + + EL++V ++ I P Sbjct: 235 NLLKG-EPLDKALEHVTAAVYEVMLKTQEMGE-------------YELQVVAAQETIVTP 280 Query: 304 EIVVQATVL 312 A L Sbjct: 281 ICQFTAVRL 289 >5TQI-A nrPDB Length = 294 Score = 302 bits (772), Expect = 2e-82, Method: Composition-based stats. Identities = 83/307 (27%), Positives = 148/307 (48%), Gaps = 29/307 (9%) Query: 5 CRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQE 64 VLSIQSHVI G+ GN AA FP+Q LG + +N+VQ SNH Y HW G +++ ++++ Sbjct: 10 KNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQ 69 Query: 65 LYEGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGE 123 L +G+ + + + D VL+G+ + V+IV+ +K NP Y CDP +G Sbjct: 70 LVDGIAAIGALKRCDAVLSGFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQT---- 125 Query: 124 GSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTV 183 G + + ++ LAD ++PN E + L+GR+I + EA+ L + GP + Sbjct: 126 GGIRPEPGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPKII 185 Query: 184 VITSSD-LPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242 ++ SP ++ + + + +R + VG GDL +A+ + Sbjct: 186 LVKHLHDRNSPADRFNMLAVT------ETEAWIGQRPLYAFPRHP---VGVGDLTSAIFV 236 Query: 243 AWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIED 302 A + ++++ A E T++ +H V++ T + EL ++ ++ +I Sbjct: 237 ARRLRG-DSVRAAFEHTLAAVHAVVKATYDARR-------------YELELIAAQDEIAR 282 Query: 303 PEIVVQA 309 P A Sbjct: 283 PSEWFGA 289 >1TD2-A nrPDB Length = 287 Score = 288 bits (736), Expect = 2e-78, Method: Composition-based stats. Identities = 84/309 (27%), Positives = 145/309 (46%), Gaps = 25/309 (8%) Query: 5 CRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQE 64 +L+IQSHV+ G+ GN AA FP++ LG + +N+VQFSNHT Y W G V+ L E Sbjct: 3 KNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTE 62 Query: 65 LYEGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGE 123 + +G+ ++ ++ D VL+GY ++ IV+++K NP+ Y CDPV+G E Sbjct: 63 IVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHP---E 119 Query: 124 GSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTV 183 V + + +P +DII PN E E+L +++ EEA+ L + GP V Sbjct: 120 KGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIV 179 Query: 184 VITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLA 243 ++ + ++L + +++ + VG GD+ + +LL Sbjct: 180 LVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDF----GMRQP---VGVGDVTSGLLLV 232 Query: 244 WTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDP 303 + L+ A E + ++ ++ T + + EL++V ++ I P Sbjct: 233 KLLQGA-TLQEALEHVTAAVYEIMVTT-------------KAMQEYELQVVAAQDRIAKP 278 Query: 304 EIVVQATVL 312 E AT L Sbjct: 279 EHYFSATKL 287 >2DDM-A nrPDB Length = 283 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 72/270 (26%), Positives = 126/270 (46%), Gaps = 16/270 (5%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 + ++++QS V+ G VGN A ++ G + AV +V SN Y + G + + Sbjct: 15 QADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFS 74 Query: 64 ELYEGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDG 122 L + + + V TGY S + ++ + + L++ +P L+ + DPV+GD G Sbjct: 75 GYLRALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSG 134 Query: 123 EGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT 182 +YV DL Y++ ++PLA ITPN FE E+L+G+ + A+ L S Sbjct: 135 ---IYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKW 191 Query: 183 VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242 VV+TS+ ++V+ + + R++ D++ GTGDLF A L+ Sbjct: 192 VVVTSASGNEENQEMQVVVV----TADSVNVISHSRVKTDLK-------GTGDLFCAQLI 240 Query: 243 AWTHKHPNNLKVACEKTVSTLHHVLQRTIQ 272 + K L A + + V++ T Q Sbjct: 241 SGLLKG-KALTDAVHRAGLRVLEVMRYTQQ 269 >5ZWB-B nrPDB Length = 296 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 69/272 (25%), Positives = 122/272 (44%), Gaps = 17/272 (6%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 + ++++QS V+ G VGN A ++ G + AV +V FSN Y + G ++ ++ Sbjct: 20 QTDIVAVQSQVVYGSVGNSIAVPAIKAQGLRVTAVPTVLFSNTPHYKTFYGGIIPAEWFA 79 Query: 64 ELYEGL-RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDG 122 L + + + + TGY + ++ + ++ +P + + DPV+GD G Sbjct: 80 GYLTALNERDALRELKAITTGYMGSADQIVLLSKWLMAIRASHPEVCILVDPVIGDTDSG 139 Query: 123 EGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT 182 MYV ++ Y+ ++P A +TPN FE E+LSG+ + EEA+ L S Sbjct: 140 ---MYVQAEIPQAYRTHLLPQAQGLTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKW 196 Query: 183 VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242 VVITS+ G + + + R+ +++ GTGDLF A L+ Sbjct: 197 VVITSAP-----GESLETITVAVVTAQVVEVFAHPRVATELK-------GTGDLFCAELV 244 Query: 243 AWTHKHPNNLKVACEKTVSTLHHVLQRTIQCA 274 + + L A + + V+ T QC Sbjct: 245 SGIVQG-KKLTTAAKDAAQRVLEVMTWTQQCG 275 >4S1M-A nrPDB Length = 287 Score = 245 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 74/273 (27%), Positives = 138/273 (50%), Gaps = 18/273 (6%) Query: 4 ECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQ 63 +VL+I S+V G+VGNR L + V + +NHTGY G + ++ Sbjct: 2 TNKVLTISSYVCSGFVGNRCGMIILDSFQIQSIFVLTTHLANHTGYPVVGGSGVLLNDFI 61 Query: 64 ELYEGLRLNNM-NKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDG 122 + + L +N++ ++++TGY + ++ V+ +K N ++ ++CDP+LGD Sbjct: 62 SIMDSLEVNHLDKDIEFLVTGYFPSSDLVYETINRVKRIKD-NKKVYFLCDPILGDN--- 117 Query: 123 EGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDT 182 G MY ++ KE ++ ADIITPN E L+G +++S EA++ +LH G Sbjct: 118 -GKMYTKSEVQDSMKE-LIKYADIITPNATELSFLTGLEVNSVSEAIKACHILHEQGIPV 175 Query: 183 VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242 +++TS +G++ +++ + N + + I +++ F G GD +LL Sbjct: 176 ILVTS----IKEGNDIILLCSFKDTLNN------KNFTIKIPRIEGDFTGVGDTLTYILL 225 Query: 243 AWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAK 275 +W K L+ A + +STL +L+ T+ A+ Sbjct: 226 SWIIKGI-PLEHAVNRAISTLQTILRNTVGTAE 257 >3MBJ-A nrPDB Length = 291 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 63/272 (23%), Positives = 114/272 (41%), Gaps = 22/272 (8%) Query: 5 CRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQE 64 ++ ++ G V L +GF++ + + SNHT Y + L + + Sbjct: 8 KKIAAVHDLSGMGRVSLTVVIPILSSMGFQVCPLPTAVLSNHTQYPGFSFLDLTDEMPKI 67 Query: 65 LYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEG 124 + E +L ++D + TGY + +V D +++ +Q P + V DPVLGD G Sbjct: 68 IAEWKKLEV--QFDAIYTGYLGSPRQIQIVSDFIKDFRQ--PDSLIVADPVLGDN----G 119 Query: 125 SMYVPEDLLPVYKE-KVVPLADIITPNQFEAELLSGRKIH---SQEEALRVMDMLHSMGP 180 +Y D+ V + ++ AD+ITPN E L + EE + +L GP Sbjct: 120 RLYTNFDMEMVKEMRHLITKADVITPNLTELFYLLDEPYKADSTDEELKEYLRLLSDKGP 179 Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240 V+ITS +P + V R+ N V + A + GTGD F ++ Sbjct: 180 QVVIITS--VPVHDEPHKTSVYAYNRQGNRYWKVTCPYL-------PAHYPGTGDTFTSV 230 Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQ 272 + + ++L +A ++ + ++ T Sbjct: 231 ITGSLMQG-DSLPMALDRATQFILQGIRATFG 261 >2I5B-A nrPDB Length = 271 Score = 115 bits (288), Expect = 2e-26, Method: Composition-based stats. Identities = 48/224 (21%), Positives = 86/224 (38%), Gaps = 34/224 (15%) Query: 52 WKGQVLNSD------ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQN 105 W QV D +L + +G+ ++ M TG + + ++E + +N Sbjct: 50 WNHQVFPIDTDTIRAQLATITDGIGVDAMK------TGMLPTVDIIELAAKTIKEKQLKN 103 Query: 106 PRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGR-KIHS 164 V DPV+ K G + PE +E++ PLA +ITPN FEA LSG ++ + Sbjct: 104 ----VVIDPVMVCK--GANEVLYPEHAQ-ALREQLAPLATVITPNLFEASQLSGMDELKT 156 Query: 165 QEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIR 224 ++ + +H++G VVIT + + ++ G + + Sbjct: 157 VDDMIEAAKKIHALGAQYVVITGGGKLKHEKAVDVLYDGETAEVLESEMIDTPYTH---- 212 Query: 225 KVDAVFVGTGDLFAAMLLAWTHKH---PNNLKVACEKTVSTLHH 265 G G F+A + A K + A E + + Sbjct: 213 -------GAGCTFSAAVTAELAKGAEVKEAIYAAKEFITAAIKE 249 >4JJP-A nrPDB Length = 267 Score = 111 bits (278), Expect = 3e-25, Method: Composition-based stats. Identities = 60/290 (20%), Positives = 112/290 (38%), Gaps = 39/290 (13%) Query: 8 LSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYE 67 L+I G G +A +G +V + + +T + + LN +++ E Sbjct: 12 LTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAITAQNTK-GVFAVEDLNKKIIKKQIE 70 Query: 68 GLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMY 127 + + + V G ++++IV+ LK+ NP+ + V DPV+ K G Sbjct: 71 AVFEDIPPR--AVKIGMVSSPE---IILEIVENLKKYNPKYL-VVDPVMISKS---GYYL 121 Query: 128 VPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITS 187 + + + ++PLA IITPN EAE ++G KIH+ ++ RV + + +GP V++ Sbjct: 122 LKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMKRVGEEILQLGPKFVLMKG 181 Query: 188 SDLPSPQ-----GSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLL 242 L G N V S+R GTG ++ + Sbjct: 182 GHLDGEAVDILVGKNIFKVYKSERIDKK------------------NTHGTGCTLSSAIT 223 Query: 243 AWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELR 292 ++ + A + + ++R+ G GV P + Sbjct: 224 SYLALGYE-ITEAVNLSKIYITEAIKRSF-----DIGHGVGPVHHFYKFE 267 >3RY7-A nrPDB Length = 304 Score = 88.7 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 19/133 (14%) Query: 127 YVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVIT 186 + +++ L DII PN+ EAELLSG K+ +++ + S+G TV+IT Sbjct: 163 VLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLIT 222 Query: 187 SSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLFAAMLLAWT 245 QG+ + SQ ++ KV+A+ GD F ++ Sbjct: 223 ----LGKQGTYFATKNQSQ--------------HIEAYKVNAIDTTAAGDTFIGAFVSRL 264 Query: 246 HKHPNNLKVACEK 258 +K +NL A + Sbjct: 265 NKSQDNLADAIDF 277 >4C5N-A nrPDB Length = 276 Score = 84.4 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 41/227 (18%), Positives = 74/227 (32%), Gaps = 27/227 (11%) Query: 50 AHWKGQVLNSDE---LQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNP 106 W V ++L L + D + TG + + ++ + Q Sbjct: 47 DTWSHDVTPLPMDVFEKQLETALSIGP----DAIKTGMLGTEEIIKRAGEVYEASNAQ-- 100 Query: 107 RLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGR-KIHSQ 165 +V DPV+ K + E + + ++P A ++TPN FEA LSG K++S Sbjct: 101 --YFVVDPVMVCKGEDE---VLNPGNTEAMIKYLLPKATVVTPNLFEAGQLSGLGKLNSI 155 Query: 166 EEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRK 225 E+ + ++ G V+I S L Sbjct: 156 EDMKKAATIIFDKGAQHVIIKGGKALDQDKSYDL-----------YYDGQTFYQLTTDMF 204 Query: 226 VDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQ 272 + G G FAA A+ + K A + + ++ + Sbjct: 205 QQSYNHGAGCTFAAATTAYLANG-KSPKEAVISAKAFVASAIKNGWK 250 >4YL5-A nrPDB Length = 263 Score = 82.9 bits (203), Expect = 1e-16, Method: Composition-based stats. Identities = 43/193 (22%), Positives = 74/193 (38%), Gaps = 24/193 (12%) Query: 77 YDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVY 136 V +G +A + + ++ +P YV DPVL GS+ L+ + Sbjct: 80 IKCVKSGMLGTTDNIAALAEFLR----AHPDYQYVLDPVLVANSG--GSLGDQATLVKAF 133 Query: 137 KEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGS 196 E ++PLA +ITPN E L+G + + L MG V++ +P Sbjct: 134 VE-LIPLATLITPNTVELRALTG-----VTDLDQATQKLFEMGAKAVLVKGGHEDTPD-- 185 Query: 197 NYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVAC 256 I A S R+ + + G+G A+ +A ++LK+A Sbjct: 186 --FIKNSLYIDGELAASSTCPRL-------EGEYHGSGCSLAS-FIAGRLALGDSLKIAV 235 Query: 257 EKTVSTLHHVLQR 269 + + L VL+ Sbjct: 236 QHAETWLFGVLKN 248 >1RK2-A nrPDB Length = 309 Score = 81.0 bits (198), Expect = 6e-16, Method: Composition-based stats. Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 20/114 (17%) Query: 138 EKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSN 197 ++++ L DIITPN+ EAE L+G ++ + E+A + +LH G TV+IT Sbjct: 175 DELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGS-------- 226 Query: 198 YLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLF-AAMLLAWTHKHP 249 R SV E R+ +V AV + GD F A++ A + P Sbjct: 227 ----------RGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKP 270 >3HYO-A nrPDB Length = 282 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 61/271 (22%), Positives = 99/271 (36%), Gaps = 30/271 (11%) Query: 17 GYVGNRAATFPLQVLGFEIDAVNSVQFSNHT-GYAHWKGQVLNSDELQELYEGLRLNNMN 75 G + +A L + +++ A+ + S HT GY L S L +++ ++ Sbjct: 16 GGISLSSALPVLTAMQYDVAALPTSLLSTHTSGYGTPAVVDL-STWLPQVFAHWTRAQLH 74 Query: 76 KYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPV 135 +D L GY + + +++ + V DPVLGD G +Y D V Sbjct: 75 -FDQALIGYVGSVALCQQITTYLEQQTLS----LLVVDPVLGD----LGQLYQGFDQDYV 125 Query: 136 YKEK-VVPLADIITPNQFEAELLSGRKIH---SQEEALRVMDMLHSMGPDTVVITSSDLP 191 + ++ AD+I PN EA LL+G E L + G V IT Sbjct: 126 AAMRQLIQQADVILPNTTEAALLTGAPYQVTPDLEVILPALQAQLKTGAHAV-ITDVQRA 184 Query: 192 SPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNN 251 G + AG V R ++ + GTGD AA++ A Sbjct: 185 DQIG---------CAWLDEAGHVQYCGAR----RLPGHYNGTGDTLAAVI-AGLLGRGYP 230 Query: 252 LKVACEKTVSTLHHVLQRTIQCAKAQAGEGV 282 L + L+ + TI + +GV Sbjct: 231 LAPTLARANQWLNMAVAETIAQNRTDDRQGV 261 >4X8F-A nrPDB Length = 309 Score = 74.8 bits (182), Expect = 5e-14, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 47/128 (36%), Gaps = 19/128 (14%) Query: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180 + ++ + ++++ D+ITPN+ EAE+L+G ++ A + D LH G Sbjct: 158 TAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGI 217 Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDA-VFVGTGDLFAA 239 + V+IT + S R+ V A GD F Sbjct: 218 EIVIITLGS------------------KGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNG 259 Query: 240 MLLAWTHK 247 L+ + Sbjct: 260 ALVTGLLQ 267 >1JXH-A nrPDB Length = 288 Score = 71.0 bits (172), Expect = 7e-13, Method: Composition-based stats. Identities = 46/243 (18%), Positives = 85/243 (34%), Gaps = 25/243 (10%) Query: 8 LSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYE 67 L+I G G +A LG +V + + +T + D + + Sbjct: 29 LTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAENT-CGVQSVYRIEPDFVAAQLD 87 Query: 68 GLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMY 127 + + + D G + + V + +Q +N V D V+ K G Sbjct: 88 SVFSDV--RIDTTKIGMLAETDIVEAVAERLQRHHVRN----VVLDTVMLAKS---GDPL 138 Query: 128 VPEDLLPVYKEKVVPLADIITPNQFEAELLSGRK-IHSQEEALRVMDMLHSMGPDTVVIT 186 + + + +++P +ITPN EA L +++E L L +MG + V++ Sbjct: 139 LSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLAMGCEAVLMK 198 Query: 187 SSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFV-GTGDLFAAMLLAWT 245 L Q ++L + R +V+ GTG +A L A Sbjct: 199 GGHLEDAQSPDWLFTREGE-------------QRFSAPRVNTKNTHGTGCTLSAALAALR 245 Query: 246 HKH 248 +H Sbjct: 246 PRH 248 >1UB0-A nrPDB Length = 258 Score = 66.3 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Query: 111 VCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALR 170 V DPV+ K G + ++ KE++ PLAD++TPN+ EAE L GR I + +EA Sbjct: 101 VVDPVMVAKS---GDPLLAKEAAAALKERLFPLADLVTPNRLEAEALLGRPIRTLKEAEE 157 Query: 171 VMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRR 207 L ++GP V++ L + + L G R Sbjct: 158 AAKALLALGPKAVLLKGGHLEGEEAVDLLATRGGVLR 194 >3RM5-A nrPDB Length = 550 Score = 58.2 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 9/129 (6%) Query: 76 KYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPV 135 K + + TG + + ++ + + +L + P+L V DPVL GS +D++ + Sbjct: 91 KCNVIKTGML-TAAAIEVLHEKLLQLGENRPKL--VVDPVLVATS---GSSLAGKDIVSL 144 Query: 136 YKEKVVPLADIITPNQFEAELLSG--RKIHSQEEALRVMDMLHSMGP-DTVVITSSDLPS 192 EKV P ADI+TPN E L G RK++ ++ ++ L + +++ +P Sbjct: 145 ITEKVAPFADILTPNIPECYKLLGEERKVNGLQDIFQIAKDLAKITKCSNILVKGGHIPW 204 Query: 193 PQGSNYLIV 201 I Sbjct: 205 NDEKEKYIT 213 >5C40-A nrPDB Length = 330 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 32/167 (19%), Positives = 61/167 (36%), Gaps = 18/167 (10%) Query: 120 WDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMG 179 G +++ P + + L+D+ N+ EAE+L+G + S +A +L G Sbjct: 169 RSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRG 228 Query: 180 PDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAA 239 V+IT +G L + + P V G GD F Sbjct: 229 CQVVIIT----LGAEGCVVLSQTEPEPKHIPTEKVKA-----------VDTTGAGDSFVG 273 Query: 240 MLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSP 286 L + +PN ++ E ++ + + ++Q A Q+ + Sbjct: 274 ALAFYLAYYPN---LSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317 >5ZWY-A nrPDB Length = 349 Score = 52.1 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 49/132 (37%), Gaps = 17/132 (12%) Query: 128 VPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITS 187 P+ + +P + PN+ EA L++G K+ E A + L +G VVIT Sbjct: 207 APKPAEVEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVIT- 265 Query: 188 SDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHK 247 L G N A V + + G GD F ++ + + Sbjct: 266 -----------LGAAGFVLSENGAEPVHVTGKHVKA----VDTTGAGDCFVGSMVYFMSR 310 Query: 248 HPNNLKVACEKT 259 N L+ AC++ Sbjct: 311 GRNLLE-ACKRA 321 >6ILS-A nrPDB Length = 313 Score = 52.1 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 39/111 (35%), Gaps = 15/111 (13%) Query: 138 EKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSN 197 +++ DI++PN+ E L+G + E+ + + H +G V++ S Sbjct: 177 NELLDSIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGS----- 231 Query: 198 YLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKH 248 + + ++ + + + G GD F A + Sbjct: 232 -ALFIQGEKPIQQSIIPAAQVV---------DTTGAGDTFTAAFAVAMVEG 272 >1VM7-A nrPDB Length = 311 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 22/151 (14%), Positives = 43/151 (28%), Gaps = 17/151 (11%) Query: 118 DKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHS 177 G + E++ D +TPN+ E E LS + + Sbjct: 158 CAKRFNGIVIFDPAPAQGINEEIFQYLDYLTPNEKEIEALSKDFFGEFLTVEKAAEKFLE 217 Query: 178 MGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLF 237 +G V++ D L+V ++++ P + GD+F Sbjct: 218 LGVKNVIVKLGD------KGVLLVNKNEKKHFPT-----------FKVKAVDTTAAGDVF 260 Query: 238 AAMLLAWTHKHPNNLKVACEKTVSTLHHVLQ 268 + N + T + V + Sbjct: 261 NGAFAVALSEGKNPEEAVIFGTAAAAISVTR 291 >3H49-A nrPDB Length = 325 Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 22/124 (17%) Query: 139 KVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNY 198 + + D + PN EA+LL+G+ + +E + D + G TVVI + G Sbjct: 187 EALSYVDYLFPNFAEAKLLTGK--ETLDE---IADCFLACGVKTVVIKT----GKDGCFI 237 Query: 199 LIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEK 258 + + AG + +G GD FA+ +A + NL+ Sbjct: 238 KRGDMTMKVPAVAGITAI------------DTIGAGDNFASGFIAALLEG-KNLRECARF 284 Query: 259 TVST 262 +T Sbjct: 285 ANAT 288 >2ABQ-A nrPDB Length = 306 Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 54/166 (32%), Gaps = 26/166 (15%) Query: 116 LGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDML 175 + G+ + E + I PN E L + I S E+A+ + L Sbjct: 147 MTQIAKERGAFVAVDTSGEALHEVLAAKPSFIKPNHHELSELVSKPIASIEDAIPHVQRL 206 Query: 176 HSMGPDTVVIT----SSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFV 231 G ++++++ + S +G ++ V + R + V Sbjct: 207 IGEGIESILVSFAGDGALFASAEGMFHVNVPSGEVRNS---------------------V 245 Query: 232 GTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQ 277 G GD A LA + +L+ A V+ C + + Sbjct: 246 GAGDSVVAGFLAALQEG-KSLEDAVPFAVAAGSATAFSDGFCTREE 290 >2JG5-A nrPDB Length = 306 Score = 44.4 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 56/132 (42%), Gaps = 19/132 (14%) Query: 131 DLLPVYKEKVVPLADI-ITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSD 189 D E V+P + I PN+ E E++ ++S + ++ +L G +V+++ Sbjct: 161 DAEKELAESVLPYHPLFIKPNKDELEVMFNTTVNSDADVIKYGRLLVDKGAQSVIVS--- 217 Query: 190 LPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHP 249 G+ Y+ S + NP G VV VG+GD A ++A Sbjct: 218 -LGGDGAIYIDKEISIKAVNPQGKVV-------------NTVGSGDSTVAGMVAGIASGL 263 Query: 250 NNLKVACEKTVS 261 +++ A ++ V+ Sbjct: 264 -SIEKAFQQAVA 274 >3KZH-A nrPDB Length = 328 Score = 44.0 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 47/129 (36%), Gaps = 27/129 (20%) Query: 70 RLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLV------------YVCDPVLG 117 + +M + T + K + + L NP ++ ++ DPV Sbjct: 112 AIADMKSIGAMNTDFIDSKREIFENAEY-TVLDSDNPEIMEYLLKNFKDKTNFILDPVSA 170 Query: 118 DKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHS 177 +K + + ++ I PN+ EAE+L+G I ++ ++ + Sbjct: 171 EKAS--------------WVKHLIKDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLG 216 Query: 178 MGPDTVVIT 186 +G V I+ Sbjct: 217 LGIKKVFIS 225 >3KD6-A nrPDB Length = 313 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 44/128 (34%), Gaps = 21/128 (16%) Query: 133 LPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPS 192 P +KV+ D+ N EA LLSG ++ ++ MGP T++I Sbjct: 158 KPEELKKVLARVDVFIVNDSEARLLSGDP-----NLVKTARIIREMGPKTLIIK------ 206 Query: 193 PQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNL 252 +G + ++ G ++ G GD FA + + N Sbjct: 207 -KGEHGALLFTDN------GIFAAPAFPLESIYDP---TGAGDTFAGGFIGHLARCGNTS 256 Query: 253 KVACEKTV 260 + K V Sbjct: 257 EAEMRKAV 264 >3LOO-A nrPDB Length = 365 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 52/151 (34%), Gaps = 22/151 (14%) Query: 129 PEDLLPVYK---EKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHS------MG 179 + YK E++ P D++ N+ EA L+ + E+ + + + Sbjct: 214 APFVPQFYKNNLEEIFPYVDVLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKR 273 Query: 180 PDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAA 239 V+IT P VL + + ++++ + G GD F Sbjct: 274 KRIVIITQGSDP---------VLLIEAGTDNVREFPVQKL---APEQMVDTNGAGDAFVG 321 Query: 240 MLLAWTHKHPNNLKVACEKTVSTLHHVLQRT 270 LA + + V + + ++QR+ Sbjct: 322 GFLAQLLQS-RTVDVCIKCGIWAAREIIQRS 351 >5EYN-A nrPDB Length = 323 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 24/150 (16%), Positives = 46/150 (30%), Gaps = 28/150 (18%) Query: 125 SMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVV 184 ++ L + V LAD++ ++ E + L+G + S EE L+ + VV Sbjct: 178 EVWSEPQELQATVMRAVGLADVVKFSEEELQFLTGTQ--SIEEGLQA---IADFQIPLVV 232 Query: 185 ITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAW 244 +T + + ++I G GD F LL Sbjct: 233 VTLG-----------------AKGALVATPNSQQIVSGKAVKPIDTTGAGDAFVGGLLYR 275 Query: 245 THKHPNNLKVACEKTVSTLHHVLQRTIQCA 274 + +T+ ++ C Sbjct: 276 LSVAQDW------HNQATILDAVKWANGCG 299 >4WJM-A nrPDB Length = 312 Score = 35.5 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 39/227 (17%), Positives = 73/227 (32%), Gaps = 32/227 (14%) Query: 69 LRLNNMNKYDYVLTGYT-RDKSFLAMVVDIVQE--LKQQNPRLVYVCDPVLGDKWDGEGS 125 L N+M D ++ S ++ V E L ++ P V DP + + Sbjct: 114 LSRNDMPYVDETISAMLFGCISLISEPCGSVYETLLAREAPNRVMFLDP------NIRAN 167 Query: 126 MYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVI 185 + ++++ LADI+ + + + + H + +GP VVI Sbjct: 168 LITVRKTHLTRMKRMIALADIVKLSDEDLDWFGEKGSHD-----EIAAEWLKLGPKLVVI 222 Query: 186 TSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWT 245 T +V + +++D+ VG GD A +LA Sbjct: 223 TKG-------------AHGAVAYTNHATVPVPGVKVDV----VDTVGAGDTVNAGILASL 265 Query: 246 HKHPNNLKVA-CEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLEL 291 H K A + +H + ++ A P E+ Sbjct: 266 HSQGLLTKDALANLSEDQIHSAVALGVRAAAVTVSRAGANPPWAHEM 312 >5KB6-A nrPDB Length = 363 Score = 35.5 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 49/159 (30%), Gaps = 21/159 (13%) Query: 129 PEDLLPVYKEKVV---PLADIITPNQFEAELLS---GRKIHSQEEALRVMDMLHSMGPDT 182 + +KE ++ P DI+ N+ EA + G + +E + L P Sbjct: 217 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQAL----PKV 272 Query: 183 VVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFV-GTGDLFAAML 241 S + + G A + V +D + + + G GD F Sbjct: 273 --------NSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGF 324 Query: 242 LAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGE 280 L+ + C + V+ R C + + Sbjct: 325 LSQLVS--DKPLTECIRAGHYAASVIIRRTGCTFPEKPD 361 >3IQ0-A nrPDB Length = 330 Score = 35.5 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 26/173 (15%), Positives = 49/173 (28%), Gaps = 33/173 (19%) Query: 85 TRDKSFLAMVVDIVQE---LKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVV 141 F +VD V++ + + N ++ DP + M ++ V+ Sbjct: 137 MGSSLFSFHMVDAVKKAVTIVKANGGVISF-DP------NIRKEMLDIPEMRDA-LHFVL 188 Query: 142 PLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIV 201 L DI P++ E LLS R + G V++ + Sbjct: 189 ELTDIYMPSEGEVLLLSPH-----STPERAIAGFLEEGVKEVIVKRGN------------ 231 Query: 202 LGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKV 254 + S + + G GD F +A + + Sbjct: 232 -----QGASYYSANEQFHVESYPVEEVDPTGAGDCFGGAWIACRQLGFDAHRA 279 >3JUL-A nrPDB Length = 320 Score = 34.4 bits (77), Expect = 0.073, Method: Composition-based stats. Identities = 24/149 (16%), Positives = 45/149 (30%), Gaps = 21/149 (14%) Query: 144 ADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLG 203 D I PN+ E + K +S EE + L P VV + + L Sbjct: 183 VDFIKPNEDEVIAILDEKTNSLEENI---RTLAEKIPYLVVSLGAKGSICAHNGKL---- 235 Query: 204 SQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTL 263 + + + G GD+F +A + + T + Sbjct: 236 --------------YQVIPPKVQERNDTGAGDVFVGAFIAGLAMNMPITETLKVATGCSA 281 Query: 264 HHVLQRTIQCAKAQAGEGVRPSPMQLELR 292 V+Q+ +A ++ ++L Sbjct: 282 SKVMQQDSSSFDLEAAGKLKNQVSIIQLE 310 >1V1S-A nrPDB Length = 309 Score = 34.0 bits (76), Expect = 0.080, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 29/120 (24%) Query: 130 EDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSD 189 + + E+ +P D++ ++ EAELL GR EEALR + P+ V+ + Sbjct: 173 PEEARGFLERALPGVDLLFLSEEEAELLFGR----VEEALRALSA-----PEVVLKRGA- 222 Query: 190 LPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLFAAMLLAWTHKH 248 + V R+ V+AV VG GD FAA LA Sbjct: 223 ------------------KGAWAFVDGRRVEGSAFAVEAVDPVGAGDAFAAGYLAGAVWG 264 >4N08-A nrPDB Length = 348 Score = 34.0 bits (76), Expect = 0.090, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 45/133 (33%), Gaps = 13/133 (9%) Query: 139 KVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGS-- 196 +V+P DII N+ EA+ + + + ++ +G Sbjct: 214 EVLPYTDIIVANRHEAKEFANMMKWDTDCVEEIARR---------AVSEVPYTGTKGRVV 264 Query: 197 NYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVAC 256 + + S G + ++D KV G GD F L+ + L+ C Sbjct: 265 VFTRDIESTVLATKDGVETVPVPQLDQDKV-IDMNGAGDAFMGGFLSAYAVGKD-LRRCC 322 Query: 257 EKTVSTLHHVLQR 269 E T V+QR Sbjct: 323 ETGHYTAQEVIQR 335 >2I6B-A nrPDB Length = 345 Score = 32.1 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 23/156 (14%), Positives = 49/156 (31%), Gaps = 15/156 (9%) Query: 129 PEDLLPVYKEKVV---PLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVI 185 + YKE ++ P DI+ N+ EA + + ++ + ++ P Sbjct: 199 APFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQAL-PK---- 253 Query: 186 TSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFV-GTGDLFAAMLLAW 244 + S + + G S V +D + + + G GD F L+ Sbjct: 254 ----MNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQ 309 Query: 245 THKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGE 280 + C + ++ R C + + Sbjct: 310 LVS--DKPLTECIRAGHYAASIIIRRTGCTFPEKPD 343 >3I3Y-A nrPDB Length = 299 Score = 31.7 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 39/131 (29%), Gaps = 38/131 (29%) Query: 120 WDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMG 179 G +++ P + P + + PL DI N+ EAELL G Sbjct: 155 SRGMTTVFNPSPVNPDFC-HLWPLIDIAVVNESEAELLQPY------------------G 195 Query: 180 PDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMD-IRKVDAVFVGTGDLFA 238 T+VIT Q +R + G GD F Sbjct: 196 VKTLVIT------------------QGAAGAWLVQEGQRQFCPAVPAEALDTTGAGDTFL 237 Query: 239 AMLLAWTHKHP 249 A++LA Sbjct: 238 AVMLASALLRG 248 >5HXD-A nrPDB Length = 237 Score = 30.9 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 42/115 (36%), Gaps = 8/115 (6%) Query: 156 LLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVV 215 LL+G K S+ E + ++H + P VV L + + S+ A + Sbjct: 126 LLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPLACIEDPRH-----SELGEWLAQAFE 180 Query: 216 MERIRMDIRKVDAVFVG-TGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQR 269 + + + F DL + A P + A EK + + ++L+ Sbjct: 181 LPLVTSVGYETPGSFGSWCADLNLHCITA--EFPPISSDEASEKYLFAMANLLRW 233 >2AFB-A nrPDB Length = 351 Score = 30.9 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 25/165 (15%), Positives = 50/165 (30%), Gaps = 10/165 (6%) Query: 100 ELKQQNPRLVYV-CDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLS 158 LK N + V V CD + ++ E+ V + D++ N+ + E + Sbjct: 162 ALKVANEKGVTVSCD------LNYRARLWTKEEAQKVMIPF-MEYVDVLIANEEDIEKVL 214 Query: 159 GRKIHSQE-EALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVME 217 G + + + ++ ++ + V + I Sbjct: 215 GISVEGLDLKTGKLNREAYAKIAEEVTRKYNFKTVGITLRESISATVNYWSVMVFENGQP 274 Query: 218 RIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVST 262 VG GD FA L+ + ++ K A E + Sbjct: 275 HFSNRYEIHIVDRVGAGDSFAGALIYGSLMGFDSQKKA-EFAAAA 318 >3LFH-A nrPDB Length = 144 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 34/93 (36%), Gaps = 12/93 (12%) Query: 92 AMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIIT-PN 150 V I++E Q++ ++ V D G ++ SM KE V + I P Sbjct: 48 KEVEKIIKEKLQEDKEIIIVVDLFGGSPFNIALSM---------MKEYDVKVITGINMPM 98 Query: 151 QFEAELLSGRKIHSQEEALRVMDMLHSMGPDTV 183 E L+ ++ E L + + G + Sbjct: 99 LVEL--LTSINVYDTTELLENISKIGKDGIKVI 129 >3N1C-A nrPDB Length = 309 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 22/54 (40%) Query: 144 ADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSN 197 +++ PNQ E L R++ ++ + + + G V+ S G + Sbjct: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVD 234 >2B20-A nrPDB Length = 403 Score = 28.6 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 94 VVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITP 149 V+ + +Q P + + D + D + D +++++PL +I P Sbjct: 217 VLTSLTHRQQLPPAVYVLIDAI--DTTHRAHELPCNADFWLAVQQELLPLVKVIAP 270 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.125 0.307 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,009,321 Number of Sequences: 36641 Number of extensions: 362939 Number of successful extensions: 1278 Number of sequences better than 10.0: 52 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1134 Number of HSP's gapped (non-prelim): 90 length of query: 312 length of database: 10,336,785 effective HSP length: 97 effective length of query: 215 effective length of database: 6,782,608 effective search space: 1458260720 effective search space used: 1458260720 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.4 bits)