BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O00487 (310 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5L4K-V nrPDB 644 0.0 5MPD-V nrPDB 397 e-111 4O8Y-B nrPDB 353 5e-98 4D10-E nrPDB 133 8e-32 4F7O-A nrPDB 133 1e-31 6FJU-A nrPDB 85 4e-17 5CW6-A nrPDB 65 3e-11 6FEC-5 nrPDB 62 4e-10 3J8B-H nrPDB 60 9e-10 5CW3-A nrPDB 48 5e-06 3JCO-U nrPDB 47 9e-06 6FVW-U nrPDB 47 1e-05 5VFQ-Z nrPDB 45 3e-05 6MSD-Z nrPDB 45 4e-05 5A5T-F nrPDB 37 0.008 3J8B-F nrPDB 37 0.010 4V4O-A nrPDB 34 0.092 3TEB-A nrPDB 32 0.45 6B6X-A nrPDB 31 0.63 1Y56-A nrPDB 28 3.6 4DVY-P nrPDB 28 3.7 6ACQ-A nrPDB 28 3.8 4DVZ-A nrPDB 28 4.5 4DAO-A nrPDB 28 4.5 5EVM-A nrPDB 28 5.6 >5L4K-V nrPDB Length = 310 Score = 644 bits (1661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/310 (100%), Positives = 310/310 (100%) Query: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE Sbjct: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60 Query: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC Sbjct: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120 Query: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN Sbjct: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180 Query: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH Sbjct: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240 Query: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL Sbjct: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300 Query: 301 AAMLDTVVFK 310 AAMLDTVVFK Sbjct: 301 AAMLDTVVFK 310 >5MPD-V nrPDB Length = 306 Score = 397 bits (1021), Expect = e-111, Method: Compositional matrix adjust. Identities = 203/310 (65%), Positives = 239/310 (77%), Gaps = 4/310 (1%) Query: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60 M+RL RL M G D DT E VYISS+ALLKMLKHGRAGVPMEVMGLMLGE Sbjct: 1 MERLQRL---MMNSKVGSA-DTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGE 56 Query: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120 FVDDYTV V+DVFAMPQSGTGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGC Sbjct: 57 FVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGC 116 Query: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180 WLS VD+NTQ+SFE L+ RAVAVVVDPIQSVKGKVVIDAFRLI+ ++ EPRQTTSN Sbjct: 117 WLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSN 176 Query: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240 G LNK +IQALIHGLNRHYYS+ I+Y K E KML+NLHK+ W GL + DY E + Sbjct: 177 TGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEES 236 Query: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300 N + K M+++A+ Y+K +EEE ++T E+L + VG+QDPK+HL E D + +NIV L Sbjct: 237 NLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVL 296 Query: 301 AAMLDTVVFK 310 A +++V K Sbjct: 297 TAGVNSVAIK 306 >4O8Y-B nrPDB Length = 240 Score = 353 bits (906), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 168/221 (76%), Positives = 185/221 (83%) Query: 21 DAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGT 80 D DT E VYISS+ALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGT Sbjct: 18 DTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT 77 Query: 81 GVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERA 140 GVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWLS VD+NTQ+SFE L+ RA Sbjct: 78 GVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRA 137 Query: 141 VAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHY 200 VAVVVDPIQSVKGKVVIDAFRLI+ ++ EPRQTTSN G LNK +IQALIHGLNRHY Sbjct: 138 VAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHY 197 Query: 201 YSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHN 241 YS+ I+Y K E KML+NLHK+ W GL + DY E + N Sbjct: 198 YSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESN 238 >4D10-E nrPDB Length = 334 Score = 133 bits (335), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 79/202 (39%), Positives = 117/202 (57%), Gaps = 11/202 (5%) Query: 33 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQ 92 IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 Query: 93 AKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQS 150 ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+DP ++ Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 Query: 151 VK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSITINYR 208 + GKV + AFR P + T L + + + YY++ ++Y Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229 Query: 209 KNELEQKMLLNLHKKSWMEGLT 230 K+ L++K+L L K W+ L+ Sbjct: 230 KSSLDRKLLELLWNKYWVNTLS 251 >4F7O-A nrPDB Length = 257 Score = 133 bits (334), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 79/202 (39%), Positives = 117/202 (57%), Gaps = 11/202 (5%) Query: 33 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQ 92 IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 Query: 93 AKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQS 150 ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+DP ++ Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 Query: 151 VK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSITINYR 208 + GKV + AFR P + T L + + + YY++ ++Y Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229 Query: 209 KNELEQKMLLNLHKKSWMEGLT 230 K+ L++K+L L K W+ L+ Sbjct: 230 KSSLDRKLLELLWNKYWVNTLS 251 >6FJU-A nrPDB Length = 228 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 2/127 (1%) Query: 30 QVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDP 89 +V I LAL K++KH + + EV GL++G+ + + D Q GT V+ +D Sbjct: 28 RVRIYPLALAKVVKHAASSLQREVAGLLVGKSAGK-VLEIWDAVTGEQYGTPAYVQ-LDE 85 Query: 90 VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQ 149 + AK+ + L ++ + +VGWYHSHPG +LS DI+TQ+ ++A+ +AVA+VVDP+ Sbjct: 86 MVMAKVAEELSKSDKNLYIVGWYHSHPGLDVFLSPTDIDTQKRYQAMFSKAVALVVDPVD 145 Query: 150 SVKGKVV 156 K + + Sbjct: 146 YAKTRRI 152 >5CW6-A nrPDB Length = 262 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 8/144 (5%) Query: 31 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDP- 89 V++ S A L + H + EVMGL +GE + V + V + +S + P Sbjct: 8 VHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPE 67 Query: 90 ---VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVV-- 144 + + + TGRP VVGWYHSHP W S VD+ TQ ++ + + V ++ Sbjct: 68 QLSAASTEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFS 127 Query: 145 --VDPIQSVKGKVVIDAFRLINAN 166 ++ + G+V+ F+ + A Sbjct: 128 CFIEDKNTKTGRVLYTCFQSVQAQ 151 >6FEC-5 nrPDB Length = 352 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 80/140 (57%), Gaps = 6/140 (4%) Query: 26 DTA-EQVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVRVIDVFAMPQSGTGV 82 D+A +QV I L +LK++KH + G EV+ G++LG V+D + + + F PQ T Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQH-TED 90 Query: 83 SVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVA 142 + + +Q +M+ L+ + VGWY S +G +++ +++Q S++ E +V Sbjct: 91 DADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVV 149 Query: 143 VVVDPIQSVKGKVVIDAFRL 162 ++ DPI++ +G + + A+RL Sbjct: 150 LIYDPIKTAQGSLSLKAYRL 169 >3J8B-H nrPDB Length = 343 Score = 60.5 bits (145), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 80/140 (57%), Gaps = 6/140 (4%) Query: 26 DTA-EQVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVRVIDVFAMPQSGTGV 82 D+A +QV I L +LK++KH + G EV+ G++LG V+D + + + F PQ T Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQH-TED 90 Query: 83 SVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVA 142 + + +Q +M+ L+ + VGWY S +G +++ +++Q S++ E +V Sbjct: 91 DADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVV 149 Query: 143 VVVDPIQSVKGKVVIDAFRL 162 ++ DPI++ +G + + A+RL Sbjct: 150 LIYDPIKTAQGSLSLKAYRL 169 >5CW3-A nrPDB Length = 255 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 3/119 (2%) Query: 29 EQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYT--VRVIDVFAMPQSGTGVSVEA 86 ++V + + + L+H + EVMGL++G F VI + + + V + + Sbjct: 9 QKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRVEISS 68 Query: 87 VDPVFQAKMLDMLK-QTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVV 144 + A + L + RP V+GWYHSHP S VD+ TQ +++ + V ++ Sbjct: 69 EQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFVGLI 127 >3JCO-U nrPDB Length = 338 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 10/115 (8%) Query: 29 EQVYISSLALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVRVIDVFAMP--QSGTGVS 83 E+V I+ L LL L H E +G++LG+ + T+RV + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 84 VEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSE 138 V +D + M +M K+ E ++GWYHS P L D+ + F+ ++ Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQ 115 >6FVW-U nrPDB Length = 304 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 10/115 (8%) Query: 29 EQVYISSLALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVRVIDVFAMP--QSGTGVS 83 E+V I+ L LL L H E +G++LG+ + T+RV + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 84 VEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSE 138 V +D + M +M K+ E ++GWYHS P L D+ + F+ ++ Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQ 115 >5VFQ-Z nrPDB Length = 286 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 17/128 (13%) Query: 28 AEQVYISSLALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVRVIDV---FAMP--QS 78 ++V + L LL ++ H G+ G V+G++LG + +V+DV FA+P + Sbjct: 2 VQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGS----WQKKVLDVSNSFAVPFDED 57 Query: 79 GTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSE 138 SV +D + M M K+ E +VGWYH+ P L DI + + Sbjct: 58 DKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCP 113 Query: 139 RAVAVVVD 146 +V V++D Sbjct: 114 NSVLVIID 121 >6MSD-Z nrPDB Length = 324 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 17/128 (13%) Query: 28 AEQVYISSLALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVRVIDV---FAMP--QS 78 ++V + L LL ++ H G+ G V+G++LG + +V+DV FA+P + Sbjct: 6 VQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGS----WQKKVLDVSNSFAVPFDED 61 Query: 79 GTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSE 138 SV +D + M M K+ E +VGWYH+ P L DI + + Sbjct: 62 DKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCP 117 Query: 139 RAVAVVVD 146 +V V++D Sbjct: 118 NSVLVIID 125 >5A5T-F nrPDB Length = 364 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Query: 52 EVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGW 111 V+G +LG VD ++V V + F++P + + V AVD F M ++ K+ E+++GW Sbjct: 122 RVIGTLLGT-VDKHSVEVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGW 179 Query: 112 Y 112 Y Sbjct: 180 Y 180 >3J8B-F nrPDB Length = 327 Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 36/60 (60%), Gaps = 2/60 (3%) Query: 53 VMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWY 112 V+G +LG VD ++V V + F++P + + V AVD F M ++ K+ E+++GWY Sbjct: 116 VIGTLLGT-VDKHSVEVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGWY 173 >4V4O-A nrPDB Length = 543 Score = 33.9 bits (76), Expect = 0.092, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 9/78 (11%) Query: 148 IQSVKGKVVID---AFRLINANMMVLGHEPR------QTTSNLGHLNKPSIQALIHGLNR 198 I +V G VI F+L NA + +LG R +TT G K I+A I+G+ + Sbjct: 290 IAAVTGGTVISEELGFKLENATLSMLGRAERVRITKDETTIVGGKGKKEDIEARINGIKK 349 Query: 199 HYYSITINYRKNELEQKM 216 + Y + +L++++ Sbjct: 350 ELETTDSEYAREKLQERL 367 >3TEB-A nrPDB Length = 266 Score = 31.6 bits (70), Expect = 0.45, Method: Compositional matrix adjust. Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 10/103 (9%) Query: 95 MLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGK 154 +L+ L++ + + W +SH GFG + GV + T+ +A E QSV+ Sbjct: 65 LLETLQKYTDTDYYLHWSNSHIGFGKYNEGVAVITRHKIKAEDEFYCTFA----QSVR-- 118 Query: 155 VVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLN 197 I A R+++ + + +E + H+N P+ + G N Sbjct: 119 -TISARRIVS---ITINYEGQDIEFYSCHMNLPNCETEDMGKN 157 >6B6X-A nrPDB Length = 637 Score = 31.2 bits (69), Expect = 0.63, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 17/25 (68%) Query: 173 EPRQTTSNLGHLNKPSIQALIHGLN 197 PRQ+T NLG L K ++ L+HG N Sbjct: 251 RPRQSTVNLGVLRKDAVNILVHGHN 275 >1Y56-A nrPDB Length = 493 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 78 SGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALS 137 G VS++ VD V + + D+ + +G+ G C +G + +Q++ + LS Sbjct: 415 CGCDVSLKKVDEVIRKGITDLQIIKRLTHLAMGFCQ---GRYCLFNGAVVVSQRTGKKLS 471 Query: 138 ERAVAVVVDPIQSVK 152 E + V PI++VK Sbjct: 472 EIDLPVARSPIKNVK 486 >4DVY-P nrPDB Length = 876 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 6/81 (7%) Query: 219 NLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPE----QLAIKN 274 NL K +GL+LQ+ ++ K S KE+ A N+NKAV E K T + A K+ Sbjct: 560 NLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEA-KSTGNYDEVKKAQKD 618 Query: 275 VGKQDPKR-HLEEHVDVLMTS 294 + K KR HLE+ V+ + S Sbjct: 619 LEKSLRKREHLEKEVEKKLES 639 >6ACQ-A nrPDB Length = 302 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Query: 102 TGRPEMVVGWYHSHPGFGCWLSGVD---INTQQSFEALSERAVAVVVDPIQ 149 T RP+ V+G + +P L V +Q++F+A+ E ++A+ DP++ Sbjct: 148 TKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIGKDPVE 198 >4DVZ-A nrPDB Length = 569 Score = 28.1 bits (61), Expect = 4.5, Method: Compositional matrix adjust. Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 6/81 (7%) Query: 219 NLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPE----QLAIKN 274 NL K +GL+LQ+ ++ K S KE+ A N+NKAV E K T + A K+ Sbjct: 300 NLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEA-KSTGNYDEVKKAQKD 358 Query: 275 VGKQDPKR-HLEEHVDVLMTS 294 + K KR HLE+ V+ + S Sbjct: 359 LEKSLRKREHLEKEVEKKLES 379 >4DAO-A nrPDB Length = 253 Score = 28.1 bits (61), Expect = 4.5, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 21/41 (51%) Query: 16 QGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGL 56 +G P +V TA+Q Y + K+ K+G GV ME L Sbjct: 164 KGVPVTVGSVFTADQFYNDDSQIEKLAKYGVLGVEMETTAL 204 >5EVM-A nrPDB Length = 529 Score = 28.1 bits (61), Expect = 5.6, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 1/90 (1%) Query: 165 ANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKS 224 N+++L + + + H K S L+ G+ R Y I N ++ KM+ N+ S Sbjct: 11 CNLLILILMISECSVGILHYEKLSKIGLVKGVTRKY-KIKSNPLTKDIVIKMIPNVSDMS 69 Query: 225 WMEGLTLQDYSEHCKHNESVVKEMLELAKN 254 G +++Y + +K LE+ KN Sbjct: 70 QCTGSVMENYKTRLNGILTPIKGALEIYKN 99 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5L4K-V nrPDB 488 e-139 5MPD-V nrPDB 439 e-124 4O8Y-B nrPDB 358 2e-99 4F7O-A nrPDB 238 2e-63 4D10-E nrPDB 238 2e-63 5CW6-A nrPDB 163 1e-40 6FJU-A nrPDB 148 2e-36 3J8B-H nrPDB 145 2e-35 6FEC-5 nrPDB 144 4e-35 5CW3-A nrPDB 142 1e-34 6MSD-Z nrPDB 125 2e-29 5VFQ-Z nrPDB 125 3e-29 6FVW-U nrPDB 122 2e-28 3JCO-U nrPDB 120 7e-28 Sequences not found previously or not previously below threshold: 3J8B-F nrPDB 71 7e-13 5A5T-F nrPDB 71 8e-13 4KIT-C nrPDB 37 0.008 2P87-A nrPDB 36 0.026 4DVY-P nrPDB 32 0.26 3BC1-A nrPDB 32 0.31 4DVZ-A nrPDB 32 0.34 3JAX-A nrPDB 30 1.2 6B6X-A nrPDB 30 1.4 4RM9-A nrPDB 29 1.9 6ID1-L nrPDB 29 2.1 4WJ0-A nrPDB 29 3.7 3J98-H nrPDB 28 4.6 >5L4K-V nrPDB Length = 310 Score = 488 bits (1257), Expect = e-139, Method: Composition-based stats. Identities = 310/310 (100%), Positives = 310/310 (100%) Query: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE Sbjct: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60 Query: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC Sbjct: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120 Query: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN Sbjct: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180 Query: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH Sbjct: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240 Query: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL Sbjct: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300 Query: 301 AAMLDTVVFK 310 AAMLDTVVFK Sbjct: 301 AAMLDTVVFK 310 >5MPD-V nrPDB Length = 306 Score = 439 bits (1130), Expect = e-124, Method: Composition-based stats. Identities = 203/310 (65%), Positives = 239/310 (77%), Gaps = 4/310 (1%) Query: 1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE 60 M+RL RL M G D DT E VYISS+ALLKMLKHGRAGVPMEVMGLMLGE Sbjct: 1 MERLQRL---MMNSKVGSA-DTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGE 56 Query: 61 FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC 120 FVDDYTV V+DVFAMPQSGTGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGC Sbjct: 57 FVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGC 116 Query: 121 WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN 180 WLS VD+NTQ+SFE L+ RAVAVVVDPIQSVKGKVVIDAFRLI+ ++ EPRQTTSN Sbjct: 117 WLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSN 176 Query: 181 LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH 240 G LNK +IQALIHGLNRHYYS+ I+Y K E KML+NLHK+ W GL + DY E + Sbjct: 177 TGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEES 236 Query: 241 NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL 300 N + K M+++A+ Y+K +EEE ++T E+L + VG+QDPK+HL E D + +NIV L Sbjct: 237 NLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVL 296 Query: 301 AAMLDTVVFK 310 A +++V K Sbjct: 297 TAGVNSVAIK 306 >4O8Y-B nrPDB Length = 240 Score = 358 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 174/242 (71%), Positives = 193/242 (79%), Gaps = 4/242 (1%) Query: 2 DRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEF 61 +RL RL M G D DT E VYISS+ALLKMLKHGRAGVPMEVMGLMLGEF Sbjct: 3 ERLQRL---MMNSKVGSA-DTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEF 58 Query: 62 VDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCW 121 VDDYTV V+DVFAMPQSGTGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCW Sbjct: 59 VDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCW 118 Query: 122 LSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNL 181 LS VD+NTQ+SFE L+ RAVAVVVDPIQSVKGKVVIDAFRLI+ ++ EPRQTTSN Sbjct: 119 LSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNT 178 Query: 182 GHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHN 241 G LNK +IQALIHGLNRHYYS+ I+Y K E KML+NLHK+ W GL + DY E + N Sbjct: 179 GLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESN 238 Query: 242 ES 243 + Sbjct: 239 LA 240 >4F7O-A nrPDB Length = 257 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 79/202 (39%), Positives = 117/202 (57%), Gaps = 11/202 (5%) Query: 33 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQ 92 IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 Query: 93 AKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQS 150 ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+DP ++ Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 Query: 151 VK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSITINYR 208 + GKV + AFR P + T L + + + YY++ ++Y Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229 Query: 209 KNELEQKMLLNLHKKSWMEGLT 230 K+ L++K+L L K W+ L+ Sbjct: 230 KSSLDRKLLELLWNKYWVNTLS 251 >4D10-E nrPDB Length = 334 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 87/257 (33%), Positives = 137/257 (53%), Gaps = 30/257 (11%) Query: 33 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQ 92 IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V A ++ Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 Query: 93 AKM--LDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQS 150 ++ KQ GR E +GWYHSHPG+GCWLSG+D++TQ + E VAVV+DP ++ Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 Query: 151 VK-GKVVIDAFRLINANMMVLGHEPRQ-TTSNLGHLNKPSIQALIHGLNRHYYSITINYR 208 + GKV + AFR P + T L + + + YY++ ++Y Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229 Query: 209 KNELEQKMLLNLHKKSWMEGLT--------------LQDYSEHCKHNESVVKEMLELAKN 254 K+ L++K+L L K W+ L+ + D SE + +E+ + + Sbjct: 230 KSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGR-----GS 284 Query: 255 YNKAVEEEDKMTPEQLA 271 + +E D+ + ++LA Sbjct: 285 FMLGLETHDRKSEDKLA 301 >5CW6-A nrPDB Length = 262 Score = 163 bits (412), Expect = 1e-40, Method: Composition-based stats. Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 8/148 (5%) Query: 27 TAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEA 86 V++ S A L + H + EVMGL +GE + V + V + +S Sbjct: 4 AVNAVHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVE 63 Query: 87 VDP----VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVA 142 + P + + + TGRP VVGWYHSHP W S VD+ TQ ++ + + V Sbjct: 64 ISPEQLSAASTEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVG 123 Query: 143 VV----VDPIQSVKGKVVIDAFRLINAN 166 ++ ++ + G+V+ F+ + A Sbjct: 124 LIFSCFIEDKNTKTGRVLYTCFQSVQAQ 151 >6FJU-A nrPDB Length = 228 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 2/127 (1%) Query: 30 QVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDP 89 +V I LAL K++KH + + EV GL++G+ + + D Q GT V+ +D Sbjct: 28 RVRIYPLALAKVVKHAASSLQREVAGLLVGKSAGK-VLEIWDAVTGEQYGTPAYVQ-LDE 85 Query: 90 VFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQ 149 + AK+ + L ++ + +VGWYHSHPG +LS DI+TQ+ ++A+ +AVA+VVDP+ Sbjct: 86 MVMAKVAEELSKSDKNLYIVGWYHSHPGLDVFLSPTDIDTQKRYQAMFSKAVALVVDPVD 145 Query: 150 SVKGKVV 156 K + + Sbjct: 146 YAKTRRI 152 >3J8B-H nrPDB Length = 343 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 42/147 (28%), Positives = 79/147 (53%), Gaps = 5/147 (3%) Query: 25 VDTAEQVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVRVIDVFAMPQSGTGV 82 +QV I L +LK++KH + G EV+ G++LG V+D + + + F PQ T Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQH-TED 90 Query: 83 SVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVA 142 + + +Q +M+ L+ + VGWY S +G +++ +++Q S++ E +V Sbjct: 91 DADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVV 149 Query: 143 VVVDPIQSVKGKVVIDAFRLINANMMV 169 ++ DPI++ +G + + A+RL M V Sbjct: 150 LIYDPIKTAQGSLSLKAYRLTPKLMEV 176 >6FEC-5 nrPDB Length = 352 Score = 144 bits (364), Expect = 4e-35, Method: Composition-based stats. Identities = 42/147 (28%), Positives = 79/147 (53%), Gaps = 5/147 (3%) Query: 25 VDTAEQVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVRVIDVFAMPQSGTGV 82 +QV I L +LK++KH + G EV+ G++LG V+D + + + F PQ T Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQH-TED 90 Query: 83 SVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVA 142 + + +Q +M+ L+ + VGWY S +G +++ +++Q S++ E +V Sbjct: 91 DADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVV 149 Query: 143 VVVDPIQSVKGKVVIDAFRLINANMMV 169 ++ DPI++ +G + + A+RL M V Sbjct: 150 LIYDPIKTAQGSLSLKAYRLTPKLMEV 176 >5CW3-A nrPDB Length = 255 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 74/172 (43%), Gaps = 16/172 (9%) Query: 25 VDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV--RVIDVFAMPQSGTGV 82 + ++V + + + L+H + EVMGL++G F VI + + + V Sbjct: 5 DSSLQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRV 64 Query: 83 SVEAVDPVFQAKMLDMLK-QTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAV 141 + + + A + L + RP V+GWYHSHP S VD+ TQ +++ + V Sbjct: 65 EISSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFV 124 Query: 142 AVVV----DPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSI 189 ++ + +S + ++ ++ F+ N T L ++ P I Sbjct: 125 GLIFSVFSEGKESKEHEIFLNCFQSDNGEA---------TEIPLEIVHTPDI 167 >6MSD-Z nrPDB Length = 324 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 11/126 (8%) Query: 27 TAEQVYISSLALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMP--QSGT 80 ++V + L LL ++ H G+ G V+G++LG + + V + FA+P + Sbjct: 5 AVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSW-QKKVLDVSNSFAVPFDEDDK 63 Query: 81 GVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERA 140 SV +D + M M K+ E +VGWYH+ P L DI + + + Sbjct: 64 DDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNS 119 Query: 141 VAVVVD 146 V V++D Sbjct: 120 VLVIID 125 >5VFQ-Z nrPDB Length = 286 Score = 125 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 11/126 (8%) Query: 27 TAEQVYISSLALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMP--QSGT 80 ++V + L LL ++ H G+ G V+G++LG + + V + FA+P + Sbjct: 1 AVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSW-QKKVLDVSNSFAVPFDEDDK 59 Query: 81 GVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERA 140 SV +D + M M K+ E +VGWYH+ P L DI + + + Sbjct: 60 DDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNS 115 Query: 141 VAVVVD 146 V V++D Sbjct: 116 VLVIID 121 >6FVW-U nrPDB Length = 304 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 10/141 (7%) Query: 29 EQVYISSLALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVRVIDVFAMP--QSGTGVS 83 E+V I+ L LL L H E +G++LG+ + T+RV + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 84 VEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAV 143 V +D + M +M K+ E ++GWYHS P L D+ + F+ ++ + Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQNNPLL 120 Query: 144 VVDPIQSVKGKVVIDAFRLIN 164 ++ ++ + DA+ I Sbjct: 121 LIVDVKQQGVGLPTDAYVAIE 141 >3JCO-U nrPDB Length = 338 Score = 120 bits (301), Expect = 7e-28, Method: Composition-based stats. Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 10/141 (7%) Query: 29 EQVYISSLALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVRVIDVFAMP--QSGTGVS 83 E+V I+ L LL L H E +G++LG+ + T+RV + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 84 VEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAV 143 V +D + M +M K+ E ++GWYHS P L D+ + F+ ++ + Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQNNPLL 120 Query: 144 VVDPIQSVKGKVVIDAFRLIN 164 ++ ++ + DA+ I Sbjct: 121 LIVDVKQQGVGLPTDAYVAIE 141 >3J8B-F nrPDB Length = 327 Score = 70.6 bits (171), Expect = 7e-13, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 14/153 (9%) Query: 10 GMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVP--MEVMGLMLGEFVDDYTV 67 +PG P V V + + L ++ V+G +LG VD ++V Sbjct: 76 ALPGPALPGPFPGGRV-----VRLHPVILASIVDSYERRNEGAARVIGTLLG-TVDKHSV 129 Query: 68 RVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDI 127 V + F++P + + V AVD F M ++ K+ E+++GWY + + Sbjct: 130 EVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGWYATGHDIT----EHSV 184 Query: 128 NTQQSFEALSERAVAVVVDPIQSVKGKVVIDAF 160 + + + + + VD G++ I A+ Sbjct: 185 LIHEYYSREAPNPIHLTVD-TSLQNGRMSIKAY 216 >5A5T-F nrPDB Length = 364 Score = 70.6 bits (171), Expect = 8e-13, Method: Composition-based stats. Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 16/163 (9%) Query: 11 MPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVP--MEVMGLMLGEFVDDYTVR 68 +PG P V V + + L ++ V+G +LG VD ++V Sbjct: 84 LPGPALPGPFPGGRV-----VRLHPVILASIVDSYERRNEGAARVIGTLLG-TVDKHSVE 137 Query: 69 VIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDIN 128 V + F++P + + V AVD F M ++ K+ E+++GWY + + Sbjct: 138 VTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGWYATGHDIT----EHSVL 192 Query: 129 TQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLG 171 + + + + + VD G++ I A+ ++ +M V G Sbjct: 193 IHEYYSREAPNPIHLTVD-TSLQNGRMSIKAY--VSTSMGVPG 232 >4KIT-C nrPDB Length = 278 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 22/141 (15%), Positives = 46/141 (32%), Gaps = 19/141 (13%) Query: 52 EVMGLMLGEF--VDDYTVRVIDVFAMPQSGTGVSV----EAVDPVFQAKMLDMLKQTGRP 105 ++ G + G + + + +PQ GT +V + + +M Sbjct: 66 QIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYLKEMEP-------- 117 Query: 106 EMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVA--VVVDPIQSVKGKVVIDAFRLI 163 +GW H+ P LS D+ T A + ++ G + A++L Sbjct: 118 ---LGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKLT 174 Query: 164 NANMMVLGHEPRQTTSNLGHL 184 + + + G+L Sbjct: 175 PSGYEWGRQNTDKGNNPKGYL 195 >2P87-A nrPDB Length = 273 Score = 35.5 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 46/128 (35%), Gaps = 17/128 (13%) Query: 47 AGVPMEVMGLMLGEF--VDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGR 104 + + ++ G M G + + + +PQ+G+ V + ++L + Sbjct: 55 SDLRTQIAGFMYGVSPPDNPQVKEIRCIVLVPQTGSHQQVNLPTQLPDHELLRDFEP--- 111 Query: 105 PEMVVGWYHSHPGFGCWLSGVDINTQQSFEALS-----ERAVAVVVDPIQSVKGKVVIDA 159 +GW H+ P LS D+ T + E+ V + G V + A Sbjct: 112 ----LGWMHTQPNELPQLSPQDVTTHAKLLTDNISWDGEKTVMITC---SFTPGSVSLTA 164 Query: 160 FRLINANM 167 ++L + Sbjct: 165 YKLTPSGY 172 >4DVY-P nrPDB Length = 876 Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Query: 219 NLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKM---TPEQLAIKNV 275 NL K +GL+LQ+ ++ K S KE+ A N+NKAV E + A K++ Sbjct: 560 NLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDL 619 Query: 276 GKQDPKR-HLEEHVDVLMTS 294 K KR HLE+ V+ + S Sbjct: 620 EKSLRKREHLEKEVEKKLES 639 >3BC1-A nrPDB Length = 195 Score = 32.1 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 23/152 (15%), Positives = 49/152 (32%), Gaps = 30/152 (19%) Query: 128 NTQQSFE----ALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGH 183 T ++ + + + V I + +VV A G R +L Sbjct: 24 KTSVLYQYTDGKFNSKFITTV--GIDFREKRVVYRA-------NGPDGAVGRGQRIHLQL 74 Query: 184 LNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKS-------WMEGLTLQDYSE 236 + ++ + S+T + ++ + +L +L + W+ L + YSE Sbjct: 75 WDTAGLE--------RFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYSE 126 Query: 237 HCKHNESVVKEMLELAKNYNKAVEEEDKMTPE 268 + K LE EE ++ + Sbjct: 127 NPDIVLCGNKSDLE--DQRAVKEEEARELAEK 156 >4DVZ-A nrPDB Length = 569 Score = 32.1 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Query: 219 NLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKM---TPEQLAIKNV 275 NL K +GL+LQ+ ++ K S KE+ A N+NKAV E + A K++ Sbjct: 300 NLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDL 359 Query: 276 GKQDPKR-HLEEHVDVLMTS 294 K KR HLE+ V+ + S Sbjct: 360 EKSLRKREHLEKEVEKKLES 379 >3JAX-A nrPDB Length = 974 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 13/93 (13%) Query: 208 RKNELEQKMLLNLHKKSWMEGLTLQ---------DYSEHCKHNESVVKEMLELAKNYNKA 258 R+ ELE+KM+ L +K L LQ D E C ++ K N+ Sbjct: 880 RRKELEEKMVSLLQEK---NDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNER 936 Query: 259 VEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVL 291 +E+E++M E L K +D L+ +D L Sbjct: 937 LEDEEEMNAE-LTAKKRKLEDECSELKRDIDDL 968 >6B6X-A nrPDB Length = 637 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 13/24 (54%), Positives = 17/24 (70%) Query: 174 PRQTTSNLGHLNKPSIQALIHGLN 197 PRQ+T NLG L K ++ L+HG N Sbjct: 252 PRQSTVNLGVLRKDAVNILVHGHN 275 >4RM9-A nrPDB Length = 587 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 32/77 (41%), Gaps = 9/77 (11%) Query: 198 RHYYSITINYRKNELEQKMLLNLHKKSWMEG-----LTLQDYSEHCKHNESVVKEMLELA 252 +H + + E +++ + K+ M L LQDY E K E + E ++ A Sbjct: 314 KHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRA 373 Query: 253 KNYNKAVEEEDKMTPEQ 269 +EEE K E+ Sbjct: 374 LQ----LEEERKRAQEE 386 >6ID1-L nrPDB Length = 802 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 58/146 (39%), Gaps = 10/146 (6%) Query: 122 LSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNL 181 +S +++++ + E V+ P QS + + + + E R N Sbjct: 647 MSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLAS-----KKDRIESLEKRLE-INR 700 Query: 182 GHLNKPSIQALIHGLNRHYYSITINYRKNELE-QKMLLNLHKKSWMEGLTLQDYSEHCKH 240 GH+ + +A + + + Y+ + K L +L + L L+ + E KH Sbjct: 701 GHMTTEAKRAA--KMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKH 758 Query: 241 NESVVKEMLE-LAKNYNKAVEEEDKM 265 +S + LE L ++ + E E ++ Sbjct: 759 EDSAIPRRLECLKEDVQRQQEREKEL 784 >4WJ0-A nrPDB Length = 322 Score = 28.6 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 48/133 (36%), Gaps = 6/133 (4%) Query: 174 PRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQD 233 PR+T + + I+ H LN+ + M NL K+W L D Sbjct: 78 PRETLLSGDLI----IRQAEHYLNKEKRLFLAKSFVTGGTKNMERNL--KNWGIKAKLSD 131 Query: 234 YSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMT 293 Y + + + M A+ + + D+ PE+ I ++ PK + + L + Sbjct: 132 YLDELNDARKITEIMNVEARIRQEYYAKWDENLPEEFKIVKRTRRPPKNEMNALISFLNS 191 Query: 294 SNIVQCLAAMLDT 306 + + +T Sbjct: 192 RLYATIITEIYNT 204 >3J98-H nrPDB Length = 297 Score = 28.2 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 18/34 (52%), Gaps = 6/34 (17%) Query: 233 DYSEHCKHNESVVKEMLELA------KNYNKAVE 260 DY + + N S K +L++A + Y KA++ Sbjct: 152 DYYKGEESNSSANKCLLKVAGYAAQLEQYQKAID 185 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.125 0.315 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,312,192 Number of Sequences: 36641 Number of extensions: 364735 Number of successful extensions: 1411 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1331 Number of HSP's gapped (non-prelim): 60 length of query: 310 length of database: 10,336,785 effective HSP length: 97 effective length of query: 213 effective length of database: 6,782,608 effective search space: 1444695504 effective search space used: 1444695504 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.4 bits)