BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= O00299 (241 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4K0G-A nrPDB 491 e-140 2D2Z-A nrPDB 343 4e-95 2R5G-A nrPDB 295 9e-81 5Y7I-A nrPDB 282 1e-76 3FY7-A nrPDB 238 2e-63 5IQY-A nrPDB 97 6e-21 5D9W-A nrPDB 96 2e-20 5ELG-A nrPDB 91 7e-19 5LOL-A nrPDB 85 3e-17 5N9U-A nrPDB 83 1e-16 2YV7-A nrPDB 79 2e-15 2YV9-A nrPDB 70 5e-13 4QQ7-A nrPDB 48 3e-06 1AW9-A nrPDB 35 0.024 4J2F-A nrPDB 34 0.046 3UBL-A nrPDB 33 0.12 3LFL-A nrPDB 33 0.13 3TOT-A nrPDB 32 0.17 5LDN-A nrPDB 32 0.19 5TX1-A nrPDB 32 0.34 3BBY-A nrPDB 30 0.72 3WD6-A nrPDB 30 0.79 1P2Z-A nrPDB 30 0.84 4PQI-A nrPDB 30 1.1 2OBE-A nrPDB 29 1.6 1E6B-A nrPDB 29 1.8 5F07-A nrPDB 29 2.1 2KLX-A nrPDB 28 2.8 5MAL-A nrPDB 28 3.6 5NI5-A nrPDB 27 5.9 4MPF-A nrPDB 27 6.3 3R2Q-A nrPDB 27 7.8 4OBV-D nrPDB 27 8.4 5NTQ-A nrPDB 27 10.0 >4K0G-A nrPDB Length = 251 Score = 491 bits (1265), Expect = e-140, Method: Compositional matrix adjust. Identities = 239/240 (99%), Positives = 239/240 (99%) Query: 2 AEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 61 AEEQPQVELFVKAGSDGAKIGN PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG Sbjct: 12 AEEQPQVELFVKAGSDGAKIGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 71 Query: 62 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 121 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS Sbjct: 72 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 131 Query: 122 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 181 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL Sbjct: 132 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 191 Query: 182 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 241 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK Sbjct: 192 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 251 >2D2Z-A nrPDB Length = 261 Score = 343 bits (880), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 160/238 (67%), Positives = 191/238 (80%) Query: 3 EEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGG 62 +++P +ELFVKAGSDG IGNCPFSQRLFM+LWLKGV F+VTTVD KR+ +Q L PG Sbjct: 14 DKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGT 73 Query: 63 QLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSN 122 PF+ + +EV TD NKIEEFLE VLCPP+Y KL+ +PESNTAG+DIFAKFSAYIKNS Sbjct: 74 HPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSR 133 Query: 123 PALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLP 182 P N+ LE+GLLK L+ LD YL SPLP+E+DE S ED S RKFLDGNE+TLADCNLLP Sbjct: 134 PEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLP 193 Query: 183 KLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 KLHIV+VV KKYR F IP+ G+ RYL+NAY+R+EF +TCP D+E+E+AY VAK L Sbjct: 194 KLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251 >2R5G-A nrPDB Length = 247 Score = 295 bits (756), Expect = 9e-81, Method: Compositional matrix adjust. Identities = 145/233 (62%), Positives = 171/233 (73%) Query: 6 PQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLP 65 P++ELFVKAGSDG IGNCPF QRLFM+LWLKGV FNVTTVD R+ E ++ L PG P Sbjct: 12 PEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPP 71 Query: 66 FLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPAL 125 FL+Y E+ TD KIEEFLE L PPRYP L+ ES G ++FAKFSAYIKN+ Sbjct: 72 FLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEA 131 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 N N EK LLK K LD+YL +PL +E+D SAE+ VS+R FLDG++LTLADC+LLPKL+ Sbjct: 132 NKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLN 191 Query: 186 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAK 238 I++V KKYR F IP F GV RYL NAYAREEF TCP+D+EIE Y VAK Sbjct: 192 IIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAK 244 >5Y7I-A nrPDB Length = 261 Score = 282 bits (721), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 143/242 (59%), Positives = 168/242 (69%), Gaps = 6/242 (2%) Query: 2 AEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 61 ++++P +ELF+KAG DG +GNCPF QRLFMVLWLKGV F VTTVD +++ ++ L PG Sbjct: 24 SDKEPSIELFIKAGHDGENVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAPG 83 Query: 62 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 121 PFLLY + TD KIEEFLE L PPRYP L+ +N ES G DIFAKFSA+IKNS Sbjct: 84 TNPPFLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNS 143 Query: 122 --NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCN 179 NP EK LL+ K LD+YL SPLPEE+D S E VS RKFLDG+ LTLADCN Sbjct: 144 PNNPL----QEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCN 199 Query: 180 LLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 LLPKLH+++V KKY F IP+ F GV RYL NA R+EF TCP D EIE AY VA Sbjct: 200 LLPKLHVIRVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVANK 259 Query: 240 LK 241 K Sbjct: 260 RK 261 >3FY7-A nrPDB Length = 250 Score = 238 bits (606), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 124/233 (53%), Positives = 155/233 (66%), Gaps = 4/233 (1%) Query: 1 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP 60 MAE + ++LFVKA DG +G+CP QRLFMVL LKGV F +TTVDT+R + ++ P Sbjct: 21 MAETK--LQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAP 78 Query: 61 GGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN 120 G QLP LLY ++ TDT +IE+FLE L PP +P LA ESNTAG D+F KFSA+IKN Sbjct: 79 GSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKN 138 Query: 121 SNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 PA ++ L + LL+AL LD+YL +PL E+ E S+R+FLDG+ LTLADC+L Sbjct: 139 PVPAQDEALYQQLLRALARLDSYLRAPLEHELAGEPQLRE--SRRRFLDGDRLTLADCSL 196 Query: 181 LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAY 233 LPKLHIV VC +R IP RGV RYL +A +EF TCP EI AY Sbjct: 197 LPKLHIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >5IQY-A nrPDB Length = 216 Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 66/223 (29%), Positives = 109/223 (48%), Gaps = 27/223 (12%) Query: 8 VELFVKAGSDGAKI-GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 VE+ VKA I G+CPFSQR+ + L K +T+ + VD + E K+ P G++P Sbjct: 6 VEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPV 65 Query: 67 LLYGT-EVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPA 124 G + D++ I + +E ++P + + P E + G IF F ++K+ + Sbjct: 66 FNSGDGKWIADSDVITQVIEE-----KFPTPSLVTPPEYASVGSKIFPSFVKFLKSKD-- 118 Query: 125 LNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 +D EK LL L+ LD +L + P ++ G ++ AD +L PKL Sbjct: 119 ASDGSEKALLDELQALDEHLKAHGP-----------------YISGENVSAADLSLGPKL 161 Query: 185 HIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDE 227 +QV + ++G+ IPE VH Y ++RE F T P ++ Sbjct: 162 FHLQVALEHFKGWKIPENLTSVHAYTKALFSRESFVKTKPANQ 204 >5D9W-A nrPDB Length = 230 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 64/218 (29%), Positives = 110/218 (50%), Gaps = 27/218 (12%) Query: 8 VELFVKAG-SDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 VE+ VKA +G+ PFSQR+ + L K V + + +D + + + K+ P G++P Sbjct: 20 VEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPV 79 Query: 67 LLYGT-EVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPA 124 G + D++ I + +E +YP + + P E + G IF+ F+ ++K+ +P Sbjct: 80 FNGGDGKWIPDSDVITQVIEE-----KYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDP- 133 Query: 125 LNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 ND EK LL L+ L+ +L + P F++G ++ AD +L PKL Sbjct: 134 -NDGSEKALLTELQALEEHLKAHGP-----------------FINGQNISAADLSLAPKL 175 Query: 185 HIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAST 222 + +QV + ++G+ IPE VH Y ++RE F T Sbjct: 176 YHLQVALEHFKGWKIPEDLTNVHAYTEALFSRESFIKT 213 >5ELG-A nrPDB Length = 221 Score = 90.5 bits (223), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 59/217 (27%), Positives = 103/217 (47%), Gaps = 25/217 (11%) Query: 8 VELFVKAGSDGA-KIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 +E+ VKA +G+CPFSQR + L K +T+ + ++ + + + P G++P Sbjct: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 Query: 67 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPAL 125 L + TD++ I LE +YP P E + G +IF F ++K+ + Sbjct: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDS-- 115 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 ND E LL L+ L+N+L S F+ G ++ D +L PKL+ Sbjct: 116 NDGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLY 159 Query: 186 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAST 222 +QV ++ +++PE+F VH Y+ ++ + F T Sbjct: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKT 196 >5LOL-A nrPDB Length = 215 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 55/220 (25%), Positives = 102/220 (46%), Gaps = 24/220 (10%) Query: 21 IGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKI 80 +G+CPFSQR+ + L K + + ++ + + + P G++P + + D++ I Sbjct: 19 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 78 Query: 81 EEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKV 139 LE +YP+ + P E + G IF F ++K+ + ND EK L+ L+ Sbjct: 79 VGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKDA--NDGSEKALVDELEA 131 Query: 140 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTI 199 L+N+L + F+ G ++T D +L PKL+ ++V Y+ +++ Sbjct: 132 LENHLKT----------------HSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV 175 Query: 200 PEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 PE+ V Y ++RE F +T E + +E A Sbjct: 176 PESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 215 >5N9U-A nrPDB Length = 218 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 60/228 (26%), Positives = 104/228 (45%), Gaps = 24/228 (10%) Query: 8 VELFVKAGSDGAKI-GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 +E+ VKA I G+CPF QR+ + L K + + ++ + + ++ P G++P Sbjct: 3 LEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPV 62 Query: 67 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALN 126 + + D++ I LE P A PE + G IF F ++K+ +P N Sbjct: 63 VKIDDKWVADSDVIVGILEEKNPEPPL----ATPPEFASVGSKIFPSFVKFLKSKDP--N 116 Query: 127 DNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHI 186 D E+ LL+ LK LD +L P F+ G ++T D +L PKL+ Sbjct: 117 DGTEQALLEELKALDGHLKVHGP-----------------FIAGEKITAVDLSLAPKLYH 159 Query: 187 VQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYE 234 ++V ++ + IP+ V Y+ ++RE F T +E + +E Sbjct: 160 LEVALGHFKNWPIPDNLTHVLNYIKLLFSRESFKKTRAAEEHVIAGWE 207 >2YV7-A nrPDB Length = 260 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 61/241 (25%), Positives = 111/241 (46%), Gaps = 28/241 (11%) Query: 6 PQVELFVKAGS-DGAKIGNCPFSQRLFMVLWL----KGVTFNVTTVDTKRRTETVQKLCP 60 P++EL +KA + DG + G C F Q FM L+L K ++ VTTVD ++ + Sbjct: 21 PEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFE 80 Query: 61 GGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN 120 P L+ + KIE + + P Y L + E T +++ K + Sbjct: 81 ATHPPILIDNGLAILENEKIERHIMKNI-PGGY-NLFVQDKEVATLIENLYVKLKLMLVK 138 Query: 121 SNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 + A N+ LL L+ ++++L++ +FL G+ + DC L Sbjct: 139 KDEAKNN----ALLSHLRKINDHLSA----------------RNTRFLTGDTMCCFDCEL 178 Query: 181 LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 +P+L ++V K + F IP + RY+ + Y + F +CP D++I + + ++ ++L Sbjct: 179 MPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDI-INHYKLQQSL 237 Query: 241 K 241 K Sbjct: 238 K 238 >2YV9-A nrPDB Length = 291 Score = 70.5 bits (171), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 65/250 (26%), Positives = 116/250 (46%), Gaps = 31/250 (12%) Query: 3 EEQPQVELFVKA-GSDGAKIGNCPFSQRLFMVLW----LKGVTFNVTTVDTKRRTETVQK 57 + +P +EL+VKA G D +IG F Q +M L+ + V TV+ +E +K Sbjct: 15 QSKPLLELYVKASGIDARRIGADLFCQEFWMELYALYEIGVARVEVKTVNVN--SEAFKK 72 Query: 58 LCPGGQLPFLLYGTE--VHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFS 115 G Q P ++ + +TD +IE + + P L +P + +++ F Sbjct: 73 NFLGAQPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVP-LFEKDPSAEKRIENLYRNFK 131 Query: 116 AYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEV--------DETSAEDEGVSQRK- 166 +++ +KG + +V D LP ++ ++ S D+ +S+RK Sbjct: 132 LFLRAKV-----EFDKGKKEPSRVED------LPAQIKVHYNRVCEQLSNIDQLLSERKS 180 Query: 167 -FLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPD 225 +L GN +T DC L+P+LH ++++ GF IP F + Y+ AY F +CP Sbjct: 181 RYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPA 240 Query: 226 DEEIELAYEQ 235 D++I Y++ Sbjct: 241 DQDIIHHYKE 250 >4QQ7-A nrPDB Length = 207 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 22/62 (35%), Positives = 37/62 (59%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEF 83 CPFSQR +VL+ KG+ F + VD + E + + P GQ+P L+ + ++N I E+ Sbjct: 14 CPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINEY 73 Query: 84 LE 85 ++ Sbjct: 74 ID 75 >1AW9-A nrPDB Length = 216 Score = 35.4 bits (80), Expect = 0.024, Method: Compositional matrix adjust. Identities = 44/171 (25%), Positives = 77/171 (45%), Gaps = 18/171 (10%) Query: 20 KIGNCPFSQ---RLFMVLWLKGVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEV 73 K+ P S R+ VL KG+ F + VD + L P GQ+P L+ G EV Sbjct: 4 KLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGDEV 63 Query: 74 HTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSA--YIKNSNPALNDNLEK 131 ++ I ++ + L A ++ A L+++ + + + N++P + L + Sbjct: 64 LFESRAINRYIASKYASEGTDLLPA---TASAAKLEVWLEVESHHFYPNASPLVFQLLVR 120 Query: 132 GLLKAL---KVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCN 179 LL V+D + L + +D A +++ K+L G+E TLAD N Sbjct: 121 PLLGGAPDAAVVDKHAEQ-LAKVLDVYEAH---LARNKYLAGDEFTLADAN 167 >4J2F-A nrPDB Length = 223 Score = 34.3 bits (77), Expect = 0.046, Method: Compositional matrix adjust. Identities = 47/212 (22%), Positives = 87/212 (41%), Gaps = 24/212 (11%) Query: 25 PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEEF 83 PFS R+ L LKG+ + D ++ + + P ++P L++G + ++ I E+ Sbjct: 14 PFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILEY 73 Query: 84 LEAVLCPPRYPKLAALNPESNTAGLDIFAKF----SAYIKNSNPALNDNLEKGLLKALKV 139 L+ P P L + E A + KF I N + LEK + L+V Sbjct: 74 LDETW--PENPLLPSDPHERAVARF--WVKFIEDKGTAIWNIFRTKGEELEKAVKNCLEV 129 Query: 140 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTI 199 L ++E + GVS K+ G+++ + D H + V+ ++ G + Sbjct: 130 LKT---------IEEHAM---GVSDDKYFGGDKIGIVDIAFCGIAHWLGVI-EEVAGVKV 176 Query: 200 PEA--FRGVHRYLSNAYAREEFASTCPDDEEI 229 E+ F +H + N PD +++ Sbjct: 177 LESQKFPRLHAWTENFKEAPIIKENLPDRDQM 208 >3UBL-A nrPDB Length = 242 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 22/175 (12%) Query: 18 GAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDT 77 GA I N + ++ + + KG+ + + + E K+ P G++P L + ++ Sbjct: 8 GASISN--YVNKVKLGILEKGLEYEQIRI-APSQEEDFLKISPMGKIPVLEMDGKFIFES 64 Query: 78 NKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKAL 137 I EFL+ + P+ PKL +P +I Y L+ + L A Sbjct: 65 GAILEFLDTIF--PQTPKLIPEDPWEAARVREISTIIETY-------LDIPARRIYLPAA 115 Query: 138 KVLDNYLTSPLPEEVDETSAEDEGVSQR-----KFLDGNELTLADCNLLPKLHIV 187 KV + + EEV T + QR ++ GN TLADC+ L ++ Sbjct: 116 KV-----SPEIVEEVHSTLVKGIKALQRVVRFSPYIAGNVFTLADCSGFAHLSVL 165 >3LFL-A nrPDB Length = 240 Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 24/44 (54%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL 67 CPF++R +VL KG+ V ++ K + E K P G +P L Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVL 75 >3TOT-A nrPDB Length = 226 Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust. Identities = 56/226 (24%), Positives = 88/226 (38%), Gaps = 50/226 (22%) Query: 25 PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLY--GTEVHTDTNKIEE 82 P+++++ +VL K + + D + + P G++P L+ G + D+ I E Sbjct: 12 PYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALF-DSRVIAE 70 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 + + L P +A L P S +++ AL D GLL A L Sbjct: 71 YAD-TLSP-----VARLIPPSGRERVEV---------RCWEALAD----GLLDAAVALRV 111 Query: 143 YLTSPLPEEVDET-------------SAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQV 189 T PE+ E+ A G++ R + +GN LTLAD + V Sbjct: 112 EQTQRTPEQRSESWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLAD---------IAV 162 Query: 190 VCK-KYRGFTIPEA-FRGVHRYLSNAYAREE----FASTCPDDEEI 229 C Y F P+ +R H L+ Y R E F T P E + Sbjct: 163 GCALAYLDFRQPQVDWREQHANLAAFYTRIEKRPSFLETQPQAENL 208 >5LDN-A nrPDB Length = 927 Score = 32.3 bits (72), Expect = 0.19, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 165 RKFLDGNELTLADCNLLPKLHIVQVVCK---KYRGFTIPEAFR 204 ++ +DG +A CN+ +VQ++ Y+GF IPE+++ Sbjct: 726 KRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYK 768 >5TX1-A nrPDB Length = 952 Score = 31.6 bits (70), Expect = 0.34, Method: Compositional matrix adjust. Identities = 12/43 (27%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 165 RKFLDGNELTLADCNLLPKLHIVQVVCK---KYRGFTIPEAFR 204 ++ +DG +A CN+ +VQ++ Y+GF +PE ++ Sbjct: 746 KRSVDGEGYNVAQCNMTKDWFLVQMLSHYNIGYQGFHVPEGYK 788 >3BBY-A nrPDB Length = 215 Score = 30.4 bits (67), Expect = 0.72, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 5/93 (5%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG-GQ---LPFLLYGTEVHTDTNK 79 P+ ++ L KG++F++ T+D E +Q G GQ +P L ++++ Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDS-GEHLQPTWQGYGQTRRVPLLQIDDFELSESSA 75 Query: 80 IEEFLEAVLCPPRYPKLAALNPESNTAGLDIFA 112 I E+LE PP + ++ L+ E+ I A Sbjct: 76 IAEYLEDRFAPPTWERIYPLDLENRARARQIQA 108 >3WD6-A nrPDB Length = 256 Score = 30.4 bits (67), Expect = 0.79, Method: Compositional matrix adjust. Identities = 39/191 (20%), Positives = 66/191 (34%), Gaps = 16/191 (8%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEF 83 CP++QR + L K + + V +D + E + ++P E+ D E Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVP----AIEIAEDVTIYESL 93 Query: 84 LEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNY 143 + YPK L + LD ++ S P ++ +K LK D Sbjct: 94 VTVEYLDEVYPKRPLLPQDPLKKALD-----KIIVEASAP-----IQSLFIKILKFSDTV 143 Query: 144 LTSPLPEEVDETSAEDEGVSQRK--FLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPE 201 + E + R FLDG+E AD + P ++ R P Sbjct: 144 NEEHVAAYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDERVRLEPS 203 Query: 202 AFRGVHRYLSN 212 + + Y+ N Sbjct: 204 KYSLLLEYIDN 214 >1P2Z-A nrPDB Length = 967 Score = 30.0 bits (66), Expect = 0.84, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 25/43 (58%), Gaps = 3/43 (6%) Query: 165 RKFLDGNELTLADCNLLPKLHIVQVVCK---KYRGFTIPEAFR 204 ++ +DG +A CN+ +VQ++ Y+GF IPE+++ Sbjct: 761 KRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYK 803 >4PQI-A nrPDB Length = 241 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 40/216 (18%), Positives = 83/216 (38%), Gaps = 21/216 (9%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVD---TKRRTETVQKLCPGGQLPFLLYGTEVHTDTNK 79 CPF+QR+++ KG+ + V R +K+ P ++P L + ++ ++ Sbjct: 40 TCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLD 99 Query: 80 IEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKV 139 + ++LE+ P L +P ++F+ + A +L K A Sbjct: 100 LIKYLESNF---EGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAKEAGPAFDH 156 Query: 140 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTI 199 L+N L D+G F G E +L D +P + + + + + I Sbjct: 157 LENAL-----------HKFDDG----PFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDI 201 Query: 200 PEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQ 235 + + ++ E + T D +E+ Y++ Sbjct: 202 TAGRQKLAAWIEEVNKIEAYKQTKTDPKELVEFYKK 237 >2OBE-A nrPDB Length = 932 Score = 29.3 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 165 RKFLDGNELTLADCNLLPKLHIVQVVCK---KYRGFTIPEAFR 204 ++ +DG +A CN+ +VQ++ Y+GF +PE ++ Sbjct: 726 KRTVDGEGYNVAQCNMTKDWFLVQMLAHYNIGYQGFYVPEGYK 768 >1E6B-A nrPDB Length = 221 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 39/178 (21%), Positives = 69/178 (38%), Gaps = 40/178 (22%) Query: 27 SQRLFMVLWLKGVTFNVTTVDTKRRTE---TVQKLCPGGQLPFLLYGTEVHTDTNKIEEF 83 + R+ + L LKG+ + V+ + + +K+ P G +P L+ G V D+ I + Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMY 79 Query: 84 L-EAVLCPPRYPK---------------LAALNPESNTAGLDIFAKFSAYIKNSNPALND 127 L E PP P+ L+ + P N A + + + ++ +N+ Sbjct: 80 LDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIR-YIEEKINVEEKTAWVNN 138 Query: 128 NLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 + KG K+L N K G+E+ LAD L P++H Sbjct: 139 AITKGFTALEKLLVN--------------------CAGKHATGDEIYLADLFLAPQIH 176 >5F07-A nrPDB Length = 213 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 42/170 (24%), Positives = 75/170 (44%), Gaps = 10/170 (5%) Query: 18 GAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLC---PGGQLPFLLYGTEVH 74 G + CP QR+ L KGV F++ VD + + + P GQ+P + G Sbjct: 6 GPAVAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDFKL 63 Query: 75 TDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLL 134 ++ I + A R P L N A +D + + A+ N + N + +L Sbjct: 64 FESRAIIRYY-AAKYEDRGPNLLG-NTLEEKALVDQWLEIEAHNFN-DLVFNIVFQVVIL 120 Query: 135 KAL-KVLDNYLTSPLPEEVDET-SAEDEGVSQRKFLDGNELTLADCNLLP 182 + + D+ L E++++ ++ +S+ K+L G+ TLAD + LP Sbjct: 121 PRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLP 170 >2KLX-A nrPDB Length = 89 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 21/48 (43%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYG 70 NCP+ +R +L KGV + T R E VQ+ P + G Sbjct: 15 NCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFPQIFIG 62 >5MAL-A nrPDB Length = 234 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 15/121 (12%) Query: 12 VKAGSDGAKIGNCPFSQRLFMVLWLK---GVTFNVTTVDTKRRTETVQKLCPGGQLPFLL 68 V AGS + G+C S + + LW G FN T R + + K QL + Sbjct: 15 VGAGSYDSSSGSCKRSTKSYPALWAASHTGTRFNFTACSGARTGDVLAK-----QLTPVN 69 Query: 69 YGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDN 128 GT++ + T + A + N + +A L AK AYI+ + PA D Sbjct: 70 SGTDLVSITIGGNDAGFA-------DTMTTCNLQGESACLARIAKARAYIQQTLPAQLDQ 122 Query: 129 L 129 + Sbjct: 123 V 123 >5NI5-A nrPDB Length = 288 Score = 27.3 bits (59), Expect = 5.9, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 170 GNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREE 218 G L +L H+VQ VCK YR T + R SN ++REE Sbjct: 15 GENLYFQGASLTEIEHLVQSVCKSYRE-TCQLRLEDLLRQRSNIFSREE 62 >4MPF-A nrPDB Length = 266 Score = 27.3 bits (59), Expect = 6.3, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 11/84 (13%) Query: 158 EDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYARE 217 ED+ + R FL G ++TLAD L +L +Q V Y E F G R + E Sbjct: 169 EDKFLGDRPFLAGQQVTLADLMALEEL--MQPVALGY------ELFEGRPRLAAWRGRVE 220 Query: 218 EF--ASTCPDDEEIELA-YEQVAK 238 F A C + I L+ EQ AK Sbjct: 221 AFLGAELCQEAHSIILSILEQAAK 244 >3R2Q-A nrPDB Length = 202 Score = 26.9 bits (58), Expect = 7.8, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 25 PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT-EVHTDTNKIEEF 83 PF ++L ++L KG+TF V + P G++P L+ E D+ I E+ Sbjct: 10 PFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAEY 69 Query: 84 LEAV-LCPPRYPK 95 +E + + P P+ Sbjct: 70 IELMNVAPAMLPR 82 >4OBV-D nrPDB Length = 490 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%), Gaps = 1/45 (2%) Query: 46 VDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE-AVLC 89 +DT + E ++ G +PF++ GT T+T I+ E + LC Sbjct: 220 MDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALC 264 >5NTQ-A nrPDB Length = 238 Score = 26.6 bits (57), Expect = 10.0, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 1/34 (2%) Query: 185 HIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREE 218 H+VQ VCK YR T + R SN ++REE Sbjct: 11 HLVQSVCKSYRE-TCQLRLEDLLRQRSNIFSREE 43 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4K0G-A nrPDB 343 5e-95 2D2Z-A nrPDB 330 3e-91 5Y7I-A nrPDB 326 5e-90 2R5G-A nrPDB 322 9e-89 3FY7-A nrPDB 287 3e-78 5N9U-A nrPDB 252 9e-68 5IQY-A nrPDB 247 4e-66 5D9W-A nrPDB 244 3e-65 5ELG-A nrPDB 243 4e-65 5LOL-A nrPDB 243 7e-65 2YV7-A nrPDB 239 9e-64 2YV9-A nrPDB 229 1e-60 4QQ7-A nrPDB 109 1e-24 Sequences not found previously or not previously below threshold: 3LFL-A nrPDB 73 9e-14 4PQI-A nrPDB 69 2e-12 2CZ2-A nrPDB 63 9e-11 2VO4-A nrPDB 63 1e-10 3QAG-A nrPDB 62 2e-10 5J5N-A nrPDB 61 5e-10 1FW1-A nrPDB 61 7e-10 1E6B-A nrPDB 60 8e-10 4CHS-A nrPDB 60 8e-10 4J2F-A nrPDB 59 1e-09 3UBL-A nrPDB 59 2e-09 1AW9-A nrPDB 59 2e-09 3WD6-A nrPDB 58 4e-09 5NR1-A nrPDB 57 8e-09 4AGS-A nrPDB 55 3e-08 5G5A-A nrPDB 54 4e-08 3TOT-A nrPDB 54 8e-08 5EY6-A nrPDB 54 8e-08 1GWC-A nrPDB 52 2e-07 5F06-A nrPDB 52 3e-07 5F07-A nrPDB 51 3e-07 4RI7-A nrPDB 51 4e-07 2JL4-A nrPDB 51 7e-07 1PN9-A nrPDB 50 1e-06 3RBT-A nrPDB 50 1e-06 1JLV-A nrPDB 49 1e-06 1OYJ-A nrPDB 49 2e-06 3R2Q-A nrPDB 49 3e-06 3IBH-A nrPDB 48 3e-06 4IGJ-A nrPDB 48 4e-06 5F05-A nrPDB 48 4e-06 2GLR-A nrPDB 47 5e-06 3PR8-A nrPDB 47 1e-05 5ZWP-A nrPDB 46 1e-05 3LG6-A nrPDB 46 1e-05 3BBY-A nrPDB 45 3e-05 1U3I-A nrPDB 44 4e-05 18GS-A nrPDB 44 6e-05 6GZF-A nrPDB 44 6e-05 4MPF-A nrPDB 44 9e-05 6N0I-A nrPDB 43 1e-04 3M1G-A nrPDB 43 1e-04 2GDR-A nrPDB 42 2e-04 6F05-A nrPDB 42 2e-04 3IR4-A nrPDB 42 3e-04 1AXD-A nrPDB 41 4e-04 2CA8-A nrPDB 41 5e-04 2PMT-A nrPDB 41 5e-04 2C3Q-A nrPDB 40 8e-04 6JWK-A nrPDB 40 0.001 4PXO-A nrPDB 39 0.001 4PTS-A nrPDB 37 0.005 1F2E-A nrPDB 36 0.019 4USS-A nrPDB 35 0.031 2PPQ-A nrPDB 35 0.031 4FN5-A nrPDB 35 0.032 6GCB-A nrPDB 34 0.064 2PBJ-A nrPDB 33 0.15 4MDC-A nrPDB 32 0.17 1G6W-A nrPDB 32 0.21 3M8N-A nrPDB 31 0.37 4LMW-A nrPDB 31 0.46 2PVQ-A nrPDB 31 0.48 4FQU-A nrPDB 31 0.61 2WDU-A nrPDB 30 1.3 3A58-B nrPDB 29 1.3 6A94-A nrPDB 29 1.6 3QMX-A nrPDB 29 2.2 2KLX-A nrPDB 28 3.0 3DKB-A nrPDB 28 3.5 1QP8-A nrPDB 28 4.5 5WJC-B nrPDB 27 5.2 6F4A-B nrPDB 27 5.5 3J6D-a nrPDB 27 8.1 >4K0G-A nrPDB Length = 251 Score = 343 bits (879), Expect = 5e-95, Method: Composition-based stats. Identities = 239/240 (99%), Positives = 239/240 (99%) Query: 2 AEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 61 AEEQPQVELFVKAGSDGAKIGN PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG Sbjct: 12 AEEQPQVELFVKAGSDGAKIGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 71 Query: 62 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 121 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS Sbjct: 72 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 131 Query: 122 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 181 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL Sbjct: 132 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 191 Query: 182 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 241 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK Sbjct: 192 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 251 >2D2Z-A nrPDB Length = 261 Score = 330 bits (847), Expect = 3e-91, Method: Composition-based stats. Identities = 160/238 (67%), Positives = 191/238 (80%) Query: 3 EEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGG 62 +++P +ELFVKAGSDG IGNCPFSQRLFM+LWLKGV F+VTTVD KR+ +Q L PG Sbjct: 14 DKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGT 73 Query: 63 QLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSN 122 PF+ + +EV TD NKIEEFLE VLCPP+Y KL+ +PESNTAG+DIFAKFSAYIKNS Sbjct: 74 HPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSR 133 Query: 123 PALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLP 182 P N+ LE+GLLK L+ LD YL SPLP+E+DE S ED S RKFLDGNE+TLADCNLLP Sbjct: 134 PEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLP 193 Query: 183 KLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 KLHIV+VV KKYR F IP+ G+ RYL+NAY+R+EF +TCP D+E+E+AY VAK L Sbjct: 194 KLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251 >5Y7I-A nrPDB Length = 261 Score = 326 bits (836), Expect = 5e-90, Method: Composition-based stats. Identities = 142/240 (59%), Positives = 167/240 (69%), Gaps = 2/240 (0%) Query: 2 AEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 61 ++++P +ELF+KAG DG +GNCPF QRLFMVLWLKGV F VTTVD +++ ++ L PG Sbjct: 24 SDKEPSIELFIKAGHDGENVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAPG 83 Query: 62 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 121 PFLLY + TD KIEEFLE L PPRYP L+ +N ES G DIFAKFSA+IKNS Sbjct: 84 TNPPFLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNS 143 Query: 122 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 181 N EK LL+ K LD+YL SPLPEE+D S E VS RKFLDG+ LTLADCNLL Sbjct: 144 --PNNPLQEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLL 201 Query: 182 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 241 PKLH+++V KKY F IP+ F GV RYL NA R+EF TCP D EIE AY VA K Sbjct: 202 PKLHVIRVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVANKRK 261 >2R5G-A nrPDB Length = 247 Score = 322 bits (825), Expect = 9e-89, Method: Composition-based stats. Identities = 145/237 (61%), Positives = 172/237 (72%) Query: 2 AEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPG 61 + P++ELFVKAGSDG IGNCPF QRLFM+LWLKGV FNVTTVD R+ E ++ L PG Sbjct: 8 TQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPG 67 Query: 62 GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS 121 PFL+Y E+ TD KIEEFLE L PPRYP L+ ES G ++FAKFSAYIKN+ Sbjct: 68 TNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNT 127 Query: 122 NPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 181 N N EK LLK K LD+YL +PL +E+D SAE+ VS+R FLDG++LTLADC+LL Sbjct: 128 QKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLL 187 Query: 182 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAK 238 PKL+I++V KKYR F IP F GV RYL NAYAREEF TCP+D+EIE Y VAK Sbjct: 188 PKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAK 244 >3FY7-A nrPDB Length = 250 Score = 287 bits (734), Expect = 3e-78, Method: Composition-based stats. Identities = 124/233 (53%), Positives = 155/233 (66%), Gaps = 4/233 (1%) Query: 1 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP 60 MAE + ++LFVKA DG +G+CP QRLFMVL LKGV F +TTVDT+R + ++ P Sbjct: 21 MAETK--LQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAP 78 Query: 61 GGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN 120 G QLP LLY ++ TDT +IE+FLE L PP +P LA ESNTAG D+F KFSA+IKN Sbjct: 79 GSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKN 138 Query: 121 SNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 PA ++ L + LL+AL LD+YL +PL E+ E S+R+FLDG+ LTLADC+L Sbjct: 139 PVPAQDEALYQQLLRALARLDSYLRAPLEHELAGEPQLRE--SRRRFLDGDRLTLADCSL 196 Query: 181 LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAY 233 LPKLHIV VC +R IP RGV RYL +A +EF TCP EI AY Sbjct: 197 LPKLHIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >5N9U-A nrPDB Length = 218 Score = 252 bits (644), Expect = 9e-68, Method: Composition-based stats. Identities = 60/233 (25%), Positives = 104/233 (44%), Gaps = 24/233 (10%) Query: 8 VELFVKAGSDGAKI-GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 +E+ VKA I G+CPF QR+ + L K + + ++ + + ++ P G++P Sbjct: 3 LEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPV 62 Query: 67 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALN 126 + + D++ I LE P PE + G IF F ++K+ +P N Sbjct: 63 VKIDDKWVADSDVIVGILEEKNPEPPLATP----PEFASVGSKIFPSFVKFLKSKDP--N 116 Query: 127 DNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHI 186 D E+ LL+ LK LD +L P F+ G ++T D +L PKL+ Sbjct: 117 DGTEQALLEELKALDGHLKVHGP-----------------FIAGEKITAVDLSLAPKLYH 159 Query: 187 VQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 ++V ++ + IP+ V Y+ ++RE F T +E + +E A Sbjct: 160 LEVALGHFKNWPIPDNLTHVLNYIKLLFSRESFKKTRAAEEHVIAGWEPKVNA 212 >5IQY-A nrPDB Length = 216 Score = 247 bits (630), Expect = 4e-66, Method: Composition-based stats. Identities = 67/235 (28%), Positives = 112/235 (47%), Gaps = 27/235 (11%) Query: 8 VELFVKAGSDGAKI-GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 VE+ VKA I G+CPFSQR+ + L K +T+ + VD + E K+ P G++P Sbjct: 6 VEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPV 65 Query: 67 LLYGT-EVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPA 124 G + D++ I + +E ++P + + P E + G IF F ++K+ + Sbjct: 66 FNSGDGKWIADSDVITQVIEE-----KFPTPSLVTPPEYASVGSKIFPSFVKFLKSKD-- 118 Query: 125 LNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 +D EK LL L+ LD +L + P ++ G ++ AD +L PKL Sbjct: 119 ASDGSEKALLDELQALDEHLKAHGP-----------------YISGENVSAADLSLGPKL 161 Query: 185 HIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 +QV + ++G+ IPE VH Y ++RE F T P ++ + + A Sbjct: 162 FHLQVALEHFKGWKIPENLTSVHAYTKALFSRESFVKTKPANQYLIAGWAPKVNA 216 >5D9W-A nrPDB Length = 230 Score = 244 bits (622), Expect = 3e-65, Method: Composition-based stats. Identities = 66/235 (28%), Positives = 114/235 (48%), Gaps = 27/235 (11%) Query: 8 VELFVKAGSD-GAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 VE+ VKA +G+ PFSQR+ + L K V + + +D + + + K+ P G++P Sbjct: 20 VEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPV 79 Query: 67 LLYGT-EVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPA 124 G + D++ I + +E +YP + + P E + G IF+ F+ ++K+ +P Sbjct: 80 FNGGDGKWIPDSDVITQVIEE-----KYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDP- 133 Query: 125 LNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 ND EK LL L+ L+ +L + P F++G ++ AD +L PKL Sbjct: 134 -NDGSEKALLTELQALEEHLKAHGP-----------------FINGQNISAADLSLAPKL 175 Query: 185 HIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 + +QV + ++G+ IPE VH Y ++RE F T E + + A Sbjct: 176 YHLQVALEHFKGWKIPEDLTNVHAYTEALFSRESFIKTKAAKEHLIAGWAPKVNA 230 >5ELG-A nrPDB Length = 221 Score = 243 bits (621), Expect = 4e-65, Method: Composition-based stats. Identities = 59/233 (25%), Positives = 108/233 (46%), Gaps = 25/233 (10%) Query: 8 VELFVKAGSDGA-KIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 +E+ VKA +G+CPFSQR + L K +T+ + ++ + + + P G++P Sbjct: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 Query: 67 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNSNPAL 125 L + TD++ I LE +YP P E + G +IF F ++K+ + Sbjct: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDS-- 115 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 ND E LL L+ L+N+L S F+ G ++ D +L PKL+ Sbjct: 116 NDGSEHALLVELEALENHLKSH----------------DGPFIAGERVSAVDLSLAPKLY 159 Query: 186 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAK 238 +QV ++ +++PE+F VH Y+ ++ + F T +++ + + Sbjct: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVN 212 >5LOL-A nrPDB Length = 215 Score = 243 bits (619), Expect = 7e-65, Method: Composition-based stats. Identities = 57/234 (24%), Positives = 107/234 (45%), Gaps = 25/234 (10%) Query: 8 VELFVKAGSDGAKI-GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPF 66 +++ VK + G+CPFSQR+ + L K + + ++ + + + P G++P Sbjct: 5 LDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV 64 Query: 67 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALN-PESNTAGLDIFAKFSAYIKNSNPAL 125 + + D++ I LE +YP+ + PE + G IF F ++K+ + Sbjct: 65 VKLDGKWVADSDVIVGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSKD--A 117 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 ND EK L+ L+ L+N+L + F+ G ++T D +L PKL+ Sbjct: 118 NDGSEKALVDELEALENHLKTH----------------SGPFVAGEKITAVDLSLAPKLY 161 Query: 186 IVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 ++V Y+ +++PE+ V Y ++RE F +T E + +E A Sbjct: 162 HLEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTKAKKEIVVAGWESKVNA 215 >2YV7-A nrPDB Length = 260 Score = 239 bits (609), Expect = 9e-64, Method: Composition-based stats. Identities = 62/241 (25%), Positives = 110/241 (45%), Gaps = 28/241 (11%) Query: 6 PQVELFVKAGS-DGAKIGNCPFSQRLFMVLWL----KGVTFNVTTVDTKRRTETVQKLCP 60 P++EL +KA + DG + G C F Q FM L+L K ++ VTTVD ++ + Sbjct: 21 PEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFE 80 Query: 61 GGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN 120 P L+ + KIE + + P Y L + E T +++ K + Sbjct: 81 ATHPPILIDNGLAILENEKIERHIMKNI-PGGY-NLFVQDKEVATLIENLYVKLKLMLVK 138 Query: 121 SNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 + A N+ LL L+ ++++L++ +FL G+ + DC L Sbjct: 139 KDEAKNN----ALLSHLRKINDHLSA----------------RNTRFLTGDTMCCFDCEL 178 Query: 181 LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 +P+L ++V K + F IP + RY+ + Y + F +CP D++I Y ++ ++L Sbjct: 179 MPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHY-KLQQSL 237 Query: 241 K 241 K Sbjct: 238 K 238 >2YV9-A nrPDB Length = 291 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 63/247 (25%), Positives = 113/247 (45%), Gaps = 19/247 (7%) Query: 3 EEQPQVELFVKA-GSDGAKIGNCPFSQRLFMVLW----LKGVTFNVTTVDTKRRTETVQK 57 + +P +EL+VKA G D +IG F Q +M L+ + V TV+ +E +K Sbjct: 15 QSKPLLELYVKASGIDARRIGADLFCQEFWMELYALYEIGVARVEVKTVNVN--SEAFKK 72 Query: 58 LCPGGQLPFLLYGTE--VHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFS 115 G Q P ++ + +TD +IE + + P L +P + +++ F Sbjct: 73 NFLGAQPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVP-LFEKDPSAEKRIENLYRNFK 131 Query: 116 AYIKNSNPALNDNLEKGLLKALKVLD--NYLTSPLPEEVDETSAEDEGVSQRK--FLDGN 171 +++ +KG + +V D + ++ S D+ +S+RK +L GN Sbjct: 132 LFLRAKV-----EFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKSRYLLGN 186 Query: 172 ELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIEL 231 +T DC L+P+LH ++++ GF IP F + Y+ AY F +CP D++I Sbjct: 187 SMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPADQDIIH 246 Query: 232 AYEQVAK 238 Y++ Sbjct: 247 HYKEQMN 253 >4QQ7-A nrPDB Length = 207 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 42/207 (20%), Positives = 81/207 (39%), Gaps = 15/207 (7%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEF 83 CPFSQR +VL+ KG+ F + VD + E + + P GQ+P L+ + ++N I E+ Sbjct: 14 CPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINEY 73 Query: 84 LEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNY 143 ++ +P+L +P F + L + K N+ Sbjct: 74 IDER---FPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKA------AEKNH 124 Query: 144 LTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAF 203 + L D + + K++ G E ++ D + P L + Y G + + Sbjct: 125 EKARL-AIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLD----HY-GIELSKNA 178 Query: 204 RGVHRYLSNAYAREEFASTCPDDEEIE 230 + +Y ++R + E++ Sbjct: 179 APLMKYAERIFSRPAYIEALTPSEKVM 205 >3LFL-A nrPDB Length = 240 Score = 73.3 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 61/160 (38%), Gaps = 14/160 (8%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL-LYGTEVHTDTNKIEE 82 CPF++R +VL KG+ V ++ K + E K P G +P L ++ ++ E Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 +L+ + L++F+K + + + + N GL + + Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK--- 148 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLP 182 + T E + F GN +++ D + P Sbjct: 149 ----------EFTKLEVLTNKKTTFFGGNSISMIDYLIWP 178 >4PQI-A nrPDB Length = 241 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 34/215 (15%), Positives = 76/215 (35%), Gaps = 21/215 (9%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVD--TKRRTETV-QKLCPGGQLPFLLYGTEVHTDTNKI 80 CPF+QR+++ KG+ + V + R +K+ P ++P L + ++ ++ + Sbjct: 41 CPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLDL 100 Query: 81 EEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVL 140 ++LE+ P L +P ++F+ + N + L Sbjct: 101 IKYLESN---FEGPSLLPKDPAKKEFAEELFSYTDKF--------NGTVYTAFKGDLAKE 149 Query: 141 DNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIP 200 D F G E +L D +P + + + + + I Sbjct: 150 AG-------PAFDHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDIT 202 Query: 201 EAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQ 235 + + ++ E + T D +E+ Y++ Sbjct: 203 AGRQKLAAWIEEVNKIEAYKQTKTDPKELVEFYKK 237 >2CZ2-A nrPDB Length = 223 Score = 63.2 bits (152), Expect = 9e-11, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 69/163 (42%), Gaps = 14/163 (8%) Query: 27 SQRLFMVLWLKGVTFNVTTVDT-----KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIE 81 S R+ + L LKG+ + + ++ ++ TE Q L P Q+P L + I Sbjct: 24 SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIM 83 Query: 82 EFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLD 141 E+LE PR D+ A ++N + E + A KV+ Sbjct: 84 EYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVIT 143 Query: 142 NYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 + + E++ +++A K+ G+E+++AD L+P++ Sbjct: 144 SGFNA--LEKILQSTA-------GKYCVGDEVSMADVCLVPQV 177 >2VO4-A nrPDB Length = 219 Score = 62.9 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 30/218 (13%), Positives = 73/218 (33%), Gaps = 15/218 (6%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEE 82 PF R+ + L KG+ + D + ++ + ++ P ++P L++ + ++ + Sbjct: 13 SPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICESLIAVQ 72 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 ++E V + + T + Y + EK Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEK----------- 121 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEA 202 + E ++ +E + + + G+ L D L+P + + + I Sbjct: 122 --EAAKKEFIEALKLLEEQLGDKTYFGGDNLGFVDIALVP-FYTWFKAYETFGTLNIESE 178 Query: 203 FRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 + +E A + PD +++ + K L Sbjct: 179 CPKFIAWAKRCLQKESVAKSLPDQQKVYEFIMDLRKKL 216 >3QAG-A nrPDB Length = 239 Score = 62.1 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 58/169 (34%), Gaps = 12/169 (7%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL-LYGTEVHTDTNKIEE 82 CP+S R +VL K + V ++ + + E P G +P L +++ ++ E Sbjct: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESVIACE 91 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 +L+ P R KL +P + FS P L L Sbjct: 92 YLDD-AYPGR--KLFPYDPYERARQKMLLELFS-----KVPHLTKECLVALRSG--REST 141 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVC 191 L + L +E E F G +++ D L P + V Sbjct: 142 NLKAALRQEFSNLEEILE-YQNTTFFGGTSISMIDYLLWPWFERLDVYG 189 >5J5N-A nrPDB Length = 231 Score = 60.9 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 27/207 (13%), Positives = 67/207 (32%), Gaps = 15/207 (7%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEE 82 PF R+ + L KGV + + D ++ + ++ P Q+P L++ + ++ I + Sbjct: 25 SPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQ 84 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 +++ V + + + F Y E+ Sbjct: 85 YIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQ----------- 133 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEA 202 + + +D + + + + G + D L+P + + F I Sbjct: 134 --EAAKKDFIDSLKLMEGELGDKPYFGGETIGYVDIALVP-FYSWFYAYETIGNFNIEAE 190 Query: 203 FRGVHRYLSNAYAREEFASTCPDDEEI 229 + Y +E + D +++ Sbjct: 191 CPKMIAYCKRCLQKETVSKALEDPQKV 217 >1FW1-A nrPDB Length = 216 Score = 60.6 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 65/163 (39%), Gaps = 14/163 (8%) Query: 27 SQRLFMVLWLKGVTFNVTTVDT-----KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIE 81 S R+ + L LKG+ + ++ ++ ++ Q L P Q+P L + I Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 82 EFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLD 141 E+LE PR S D+ A ++N + E L A + Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAIT 136 Query: 142 NYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 + E++ +++A + G+E+T+AD L+P++ Sbjct: 137 CGFNA--LEQILQSTA-------GIYCVGDEVTMADLCLVPQV 170 >1E6B-A nrPDB Length = 221 Score = 60.2 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 10/161 (6%) Query: 29 RLFMVLWLKGVTFNVTTVDTKRRTE---TVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 R+ + L LKG+ + V+ + + +K+ P G +P L+ G V D+ I +L+ Sbjct: 22 RVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMYLD 81 Query: 86 AVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLT 145 +YP+ L + + ++ + S + P N + + + + + V + Sbjct: 82 E-----KYPEPPLLPRDLHKRAVN-YQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAW 135 Query: 146 SPLPEEVDETSAEDEGVS-QRKFLDGNELTLADCNLLPKLH 185 T+ E V+ K G+E+ LAD L P++H Sbjct: 136 VNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIH 176 >4CHS-A nrPDB Length = 219 Score = 60.2 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 28/218 (12%), Positives = 74/218 (33%), Gaps = 15/218 (6%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEE 82 PF R+ + L KG+ + D + ++ + ++ P ++P L++ + +++ + Sbjct: 13 SPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISESLIAVQ 72 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 ++E V + + + + + EK Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEK----------- 121 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEA 202 + E ++ +E + + + G+ + D L+P +V + + I Sbjct: 122 --EAAKKEFIEALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVY-ETFGSLNIENE 178 Query: 203 FRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 + +E A + PD ++ ++ K L Sbjct: 179 CPRFVAWAKRCLQKESVAKSLPDQHKVYEFVVEIRKKL 216 >4J2F-A nrPDB Length = 223 Score = 59.4 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 39/220 (17%), Positives = 80/220 (36%), Gaps = 26/220 (11%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEE 82 PFS R+ L LKG+ + D ++ + + P ++P L++G + ++ I E Sbjct: 13 SPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILE 72 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGL---LKALKV 139 +L+ + I N + LEK + L+ LK Sbjct: 73 YLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEELEKAVKNCLEVLKT 132 Query: 140 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLAD---CNLLPKLHIV-QVVCKKYR 195 ++ + GVS K+ G+++ + D C + L ++ +V K Sbjct: 133 IEEH---------------AMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEVAGVKVL 177 Query: 196 GFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQ 235 + F +H + N PD +++ +++ Sbjct: 178 E---SQKFPRLHAWTENFKEAPIIKENLPDRDQMTAFFKR 214 >3UBL-A nrPDB Length = 242 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 44/223 (19%), Positives = 80/223 (35%), Gaps = 12/223 (5%) Query: 17 DGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTD 76 GA I N + ++ + + KG+ + + + E K+ P G++P L + + Sbjct: 7 HGASISN--YVNKVKLGILEKGLEYEQIRIAPSQE-EDFLKISPMGKIPVLEMDGKFIFE 63 Query: 77 TNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKA 136 + I EFL+ + P+ PKL +P +I Y+ PA L + Sbjct: 64 SGAILEFLDTIF--PQTPKLIPEDPWEAARVREISTIIETYL--DIPARRIYLPAAKVSP 119 Query: 137 LKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRG 196 V + + T V A V ++ GN TLADC+ L ++ + + Sbjct: 120 EIVEEVHST-----LVKGIKALQRVVRFSPYIAGNVFTLADCSGFAHLSVLDEELRPFYP 174 Query: 197 FTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKA 239 P + + + D++I AK Sbjct: 175 NNHPLDLLNGWKEYFVFMKTKAGPALVEKDKQILKKILARAKT 217 >1AW9-A nrPDB Length = 216 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 43/203 (21%), Positives = 74/203 (36%), Gaps = 15/203 (7%) Query: 29 RLFMVLWLKGVTFNVTTVDTK---RRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 R+ VL KG+ F + VD + L P GQ+P L+ G EV ++ I ++ Sbjct: 16 RVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAINRYIA 75 Query: 86 AVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLL---KALKVLDN 142 + L + + + + + N++P + L + LL V+D Sbjct: 76 SKYASEG-TDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRPLLGGAPDAAVVDK 134 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEA 202 + + + +++ K+L G+E TLAD N L + K P Sbjct: 135 H----AEQLAKVLDVYEAHLARNKYLAGDEFTLADANHASYLLYLSKTPKAGLVAARP-- 188 Query: 203 FRGVHRYLSNAYAREEFASTCPD 225 V + AR F T Sbjct: 189 --HVKAWWEAIVARPAFQKTVAA 209 >3WD6-A nrPDB Length = 256 Score = 57.9 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 70/199 (35%), Gaps = 14/199 (7%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLP-FLLYGTEVHTDTNKIEE 82 CP++QR + L K + + V +D + E + ++P + ++ E Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAIEIAEDVTIYESLVTVE 97 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 +L+ V P+ P L +P + I ++ + K L + V + Sbjct: 98 YLDEVY--PKRP-LLPQDP--------LKKALDKIIVEASAPIQSLFIKILKFSDTVNEE 146 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEA 202 ++ + + + E FLDG+E AD + P ++ R P Sbjct: 147 HVAAY--HKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDERVRLEPSK 204 Query: 203 FRGVHRYLSNAYAREEFAS 221 + + Y+ N + Sbjct: 205 YSLLLEYIDNMLKDSAVSQ 223 >5NR1-A nrPDB Length = 228 Score = 56.7 bits (135), Expect = 8e-09, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 54/170 (31%), Gaps = 7/170 (4%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLY----GTEVHTDTNK 79 P S+++ + L K + F V L P G P L+ V +T Sbjct: 13 DPASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRA 72 Query: 80 IEEFLEAVLCPPRYPKLAALNPESNTAGLDIF-AKFSAYIKNSNPALNDNLEKGLLKALK 138 I E +E P L F KF + L++ +EK LL+ Sbjct: 73 ILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNG--FLLHEKMEKRLLRMGA 130 Query: 139 VLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQ 188 L + + R +L G ++LAD L ++ Sbjct: 131 PDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHLSVID 180 >4AGS-A nrPDB Length = 471 Score = 54.8 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 42/234 (17%), Positives = 83/234 (35%), Gaps = 24/234 (10%) Query: 8 VELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRR-TETVQKLCPGGQLPF 66 ++L+V A CPF R+ +V K V+++ V + + +++ P +P Sbjct: 27 LKLYVSAT--------CPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPT 78 Query: 67 L---LYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNP 123 L ++ I ++L+ P L + A+ +I ++ Sbjct: 79 LEVGNADKRFMFESMLIAQYLDNSGAPAG--ALMGSSAAQRHQIEFFLAQVGDFIGAAHG 136 Query: 124 ALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPK 183 L D L + K +D+ VD A ++ + + E T+AD L+P Sbjct: 137 LLRDPLSG---EKRKAMDDN-----AAYVDGLLAANQ--TTGPYYCDGEFTMADVALVPF 186 Query: 184 LHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVA 237 L ++ Y G+ + + + A R T P + Y + Sbjct: 187 LVRLKPALMYYAGYDVFCKAPRMKALWAAAAQRASVRETSPTAAQCIENYRHLV 240 Score = 46.7 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 29/200 (14%), Positives = 60/200 (30%), Gaps = 19/200 (9%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLP-FLLYGTEVHTDTNKIEE 82 CPF R + L+ ++ V + E + + P +P E ++ I + Sbjct: 261 CPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQ 320 Query: 83 FLEAVLCPPRYPKL---AALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKV 139 +++ V A E + F + + ++ + L A Sbjct: 321 YIDCVATKGSALVPRGDAEKEYEVGFFVENA-GYFVGGLMSWIIRGGEDAKAELQWAAGE 379 Query: 140 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYR-GFT 198 L+ L + F G + D +LP L + ++ G+ Sbjct: 380 LEQQLAKH-------------PFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGYD 426 Query: 199 IPEAFRGVHRYLSNAYAREE 218 + F ++ A E Sbjct: 427 LFAHFPLLNGLAEAGMATPE 446 >5G5A-A nrPDB Length = 221 Score = 54.4 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 36/216 (16%), Positives = 76/216 (35%), Gaps = 15/216 (6%) Query: 26 FSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEEFL 84 F R + L K V F+ D ++ + ++ P ++P L++ ++ E++ Sbjct: 15 FGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVLIHNGNPVCESLIQIEYI 74 Query: 85 EAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL 144 + V P + P L +P A + F I A + + + Sbjct: 75 DEV-WPSKTP-LLPSDP-YQRAQAKFWGDF---IDKKVYASARLIWGAKGEEHE------ 122 Query: 145 TSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFR 204 + E ++ + + + + G D L+ + +K+ F+I Sbjct: 123 -AGKKEFIEILKTLESELGDKTYFGGETFGYVDIALI-GFYSWFEAYEKFGSFSIEAECP 180 Query: 205 GVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 240 + + RE A + PD E+I ++ K L Sbjct: 181 KLIAWGKRCVERESVAKSLPDSEKIIKFVPELRKKL 216 >3TOT-A nrPDB Length = 226 Score = 53.6 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 38/213 (17%), Positives = 77/213 (36%), Gaps = 20/213 (9%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLL-YGTEVHTDTNKIE 81 P+++++ +VL K + + D + + P G++P L+ D+ I Sbjct: 10 ASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIA 69 Query: 82 EFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLD 141 E+ + + R + + + A+ +E+ + + Sbjct: 70 EYADTLSPVARLIPPSGRERVEVRCWEALADGLL------DAAVALRVEQTQRTPEQRSE 123 Query: 142 NYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPE 201 +++T + + A G++ R + +GN LTLAD + Y F P+ Sbjct: 124 SWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVG--------CALAYLDFRQPQ 175 Query: 202 -AFRGVHRYLSNAY----AREEFASTCPDDEEI 229 +R H L+ Y R F T P E + Sbjct: 176 VDWREQHANLAAFYTRIEKRPSFLETQPQAENL 208 >5EY6-A nrPDB Length = 217 Score = 53.6 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 75/206 (36%), Gaps = 26/206 (12%) Query: 29 RLFMVLWLKGVTFNVTTVDTKR---RTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 R+ + L K V F + VD + + K+ P GQ+P + ++ I ++ Sbjct: 17 RVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESISLFESRSICRYVC 76 Query: 86 AVLCPPRYPKLAALNP-ESNTAGLDIFAKFSAYIKNS---------NPALNDNLEKGLLK 135 L NP E + + A+ ++ +S P +N ++G++K Sbjct: 77 EKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVIK 136 Query: 136 ALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYR 195 + + ++ + + +FL G+E T AD + LP + K Sbjct: 137 QNE----------EKLGKVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYLVNATDKGH 186 Query: 196 GFTIPEAFRGVHRYLSNAYAREEFAS 221 FT E +S+ RE + Sbjct: 187 LFTSRENVGRWWNEISD---RESWKK 209 >1GWC-A nrPDB Length = 230 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 56/142 (39%), Gaps = 12/142 (8%) Query: 15 GSDGAKIGN--CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGT 71 G D +G PF R+ + L LKG+++ D +++E + K P ++P L++ Sbjct: 4 GDDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVLIHNG 63 Query: 72 EVHTDTNKIEEFLEAVLCPPRYPKLAALNPE--------SNTAGLDIFAKFSAYIKNSNP 123 ++ I ++++ V P L +P + A + +++ Sbjct: 64 APVCESMIILQYIDEVFASTG-PSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTE 122 Query: 124 ALNDNLEKGLLKALKVLDNYLT 145 +K A+ VL+ L Sbjct: 123 EEKSEGKKQAFAAVGVLEGALR 144 >5F06-A nrPDB Length = 216 Score = 51.7 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 74/205 (36%), Gaps = 25/205 (12%) Query: 29 RLFMVLWLKGVTFNVTTVDTK---RRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 R+ L K + F + VD + P GQ+P L ++ I ++ Sbjct: 15 RVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIA 74 Query: 86 AVLCPPRYPKLAALN-PESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL 144 Y + N E+ + ++ + ++ NPA+ + + ++ L+ Sbjct: 75 EKFKGTGYDLIRHENLKEAASV--KVWTEVESH--RYNPAIAPIVFQFMVAPLRG----- 125 Query: 145 TSPLPEEVDETSAE--------DEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRG 196 SP +D+ + + +S K+L G+ +LAD + LP + + K Sbjct: 126 NSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYL----MKTPA 181 Query: 197 FTIPEAFRGVHRYLSNAYAREEFAS 221 ++ V + + +R F Sbjct: 182 ASVVNERPHVKAWWEDISSRPAFKK 206 >5F07-A nrPDB Length = 213 Score = 51.3 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 42/170 (24%), Positives = 75/170 (44%), Gaps = 10/170 (5%) Query: 18 GAKIGNCPFSQRLFMVLWLKGVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEVH 74 G + CP QR+ L KGV F++ VD +++ P GQ+P + G Sbjct: 6 GPAVAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDFKL 63 Query: 75 TDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLL 134 ++ I + A R P L E A +D + + A+ N + N + +L Sbjct: 64 FESRAIIRYYAAKY-EDRGPNLLGNTLE-EKALVDQWLEIEAHNFN-DLVFNIVFQVVIL 120 Query: 135 KAL-KVLDNYLTSPLPEEVDE-TSAEDEGVSQRKFLDGNELTLADCNLLP 182 + + D+ L E++++ ++ +S+ K+L G+ TLAD + LP Sbjct: 121 PRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLP 170 >4RI7-A nrPDB Length = 215 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 59/162 (36%), Gaps = 6/162 (3%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKR---RTETVQKLCPGGQLPFLLYGTEVHTDTNKI 80 C R+ L K V F++ +D + + K+ P GQ+P + ++ I Sbjct: 13 CTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAI 72 Query: 81 EEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVL 140 ++ L + S +I + P D + L ++ V Sbjct: 73 CRYICDKYADKGNKSLYGTDILSK---ANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVD 129 Query: 141 DNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLP 182 + + + + ++ + Q +FL G+E + AD + LP Sbjct: 130 EALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLP 171 >2JL4-A nrPDB Length = 213 Score = 50.5 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 75/220 (34%), Gaps = 42/220 (19%) Query: 27 SQRLFMVLWLKGVTFNVTTVDTKRR---TETVQKLCPGGQLPFLLYGTEVHTDTNKIEEF 83 S RL + L LKGV + V + + + L P +P L G +V + I E+ Sbjct: 13 SHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQVLIQSPAIIEW 72 Query: 84 LEAVLCPPRYPKLAALNPES----------NTAGLDIFAKFSAYIKNSNPALNDNLEKGL 133 LE +YP A L ++ G DI P N + + L Sbjct: 73 LEE-----QYPTPALLPADADGRQRVRALAAIVGCDIH-----------PINNRRILEYL 116 Query: 134 LKALKVLDNYLTSPLPEEVDE-----TSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQ 188 K + + + + + + ++ G+ TLADC L+P++ Sbjct: 117 RKTFGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQV---- 172 Query: 189 VVCKKYRGFTIP-EAFRGVHRYLSNAYAREEFASTCPDDE 227 + R F + + + + + F P + Sbjct: 173 ---ESARRFQVDLTPYPLIRAVDAACGELDAFRRAAPAAQ 209 >1PN9-A nrPDB Length = 209 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 37/193 (19%), Positives = 69/193 (35%), Gaps = 39/193 (20%) Query: 22 GNCPFSQRLFMVLWLKGVTFNVTTVDTKR----RTETVQKLCPGGQLPFLLYGTEVHTDT 77 G+ P + + M GV N+ D + + E KL P +P L+ ++ Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTDLMKGEHMKPE-FLKLNPQHCIPTLVDNGFALWES 65 Query: 78 NKIEEFLEAVLCPPRYPKLAALNPESNTAGLD--------IFAKFSAY----IKNSNPAL 125 I+ +L KL +P+ ++ +F+ Y I PA Sbjct: 66 RAIQIYLAEKYGKDD--KLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAKQPA- 122 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 N EK + A+ L+ +L +++ GN+LT+AD +L + Sbjct: 123 NPENEKKMKDAVGFLNTFLEG------------------QEYAAGNDLTIADLSLAATIA 164 Query: 186 IVQVVCKKYRGFT 198 +V + + Sbjct: 165 TYEVAGFDFAPYP 177 >3RBT-A nrPDB Length = 246 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 66/175 (37%), Gaps = 27/175 (15%) Query: 25 PFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLY----GTEVHTDTNKI 80 P+ R+ +VL K + + V +D R E + P ++P L G ++ I Sbjct: 36 PYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLFESVVI 95 Query: 81 EEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVL 140 ++L+ L + +P Y+K + L + + + +L+ Sbjct: 96 CDYLDEKYTRH---TLHSHDP---------------YVKAQDRLLIERFNELIKGSLECF 137 Query: 141 DNYLTSPLPEEVDETSAEDEGVSQR--KFLDGNELTLADCNLLP---KLHIVQVV 190 D + + ++ ++ R + GN + D + P +L++++ V Sbjct: 138 DTNFAFGSEQIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLRCV 192 >1JLV-A nrPDB Length = 209 Score = 49.4 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 65/193 (33%), Gaps = 39/193 (20%) Query: 22 GNCPFSQRLFMVLWLKGVTFNVTTVDT----KRRTETVQKLCPGGQLPFLLYGTEVHTDT 77 G+ P + + M GV N+ + + E K+ P +P L+ ++ Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTNLMAGEHMKPE-FLKINPQHCIPTLVDNGFALWES 65 Query: 78 NKIEEFLEAVLCPPRYPKLAALNPESNTAGLD--------IFAKFSAY----IKNSNPAL 125 I +L KL +P+ ++ +F+ Y I PA Sbjct: 66 RAICTYLAEKYGKDD--KLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAKQPA- 122 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 N EK + A+ L+ +L K++ G+ LT+AD +L + Sbjct: 123 NAENEKKMKDAVDFLNTFLDGH------------------KYVAGDSLTIADLTVLATVS 164 Query: 186 IVQVVCKKYRGFT 198 V + + Sbjct: 165 TYDVAGFELAKYP 177 >1OYJ-A nrPDB Length = 231 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 3/76 (3%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP-GGQLPFLLYGTEVHTDTNKIEE 82 PF QR + + KG+ F D +++ + + P ++P LL+ +++ I + Sbjct: 15 SPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLHAGRPVSESLVILQ 74 Query: 83 FLEAVLCPPRYPKLAA 98 +L+ P P L Sbjct: 75 YLDDAF--PGTPHLLP 88 >3R2Q-A nrPDB Length = 202 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 44/206 (21%), Positives = 76/206 (36%), Gaps = 20/206 (9%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLL-YGTEVHTDTNKIEE 82 PF ++L ++L KG+TF V + P G++P L+ E D+ I E Sbjct: 9 SPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAE 68 Query: 83 FLE-AVLCP---PRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALK 138 ++E + P PR P + + I ++ E LL+ + Sbjct: 69 YIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQRE 128 Query: 139 VLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFT 198 ++ L VD T D N T+A + L+ +V G+ Sbjct: 129 KINRSLDVLEGYLVDGTLKTDTV---------NLATIAIACAVGYLNFRRVA----PGWC 175 Query: 199 IPEAFRGVHRYLSNAYAREEFASTCP 224 + + + + N ++RE FA T P Sbjct: 176 V--DRPHLVKLVENLFSRESFARTEP 199 >3IBH-A nrPDB Length = 233 Score = 48.2 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 34/220 (15%), Positives = 67/220 (30%), Gaps = 46/220 (20%) Query: 25 PFSQRLFMVLWLKGVTFNVTTVDTK------RRTETVQKLCPGGQLPFLLYGTEVHTDTN 78 P+ R+ + L K + +V V ++ E + K G L + + Sbjct: 28 PYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECT 87 Query: 79 KIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALK 138 I E+++A+ P L P +N E LL + Sbjct: 88 AITEYIDALDGT---PTLTGKTPLEKGVIH---------------MMNKRAELELLDPVS 129 Query: 139 VLDNYLTSPLPEEVDETSAE-----------------DEGVSQRKFLDGNELTLADCNLL 181 V ++ T L EV+ + D + +R ++ G+ ++AD ++ Sbjct: 130 VYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMADITVI 189 Query: 182 PKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAS 221 L + +PE + + R Sbjct: 190 AGL-----IFAAIVKLQVPEECEALRAWYKRMQQRPSVKK 224 >4IGJ-A nrPDB Length = 242 Score = 47.8 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 43/207 (20%), Positives = 75/207 (36%), Gaps = 21/207 (10%) Query: 29 RLFMVLWLKGVTFNVTTVDTKRRTE---TVQKLCPGGQLPFLLYGTEVHT----DTNKIE 81 R+ + L LKG+ + VD + + Q P Q+P L + T + I Sbjct: 38 RVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMAIL 97 Query: 82 EFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN-SNPALNDNLEKGLLKALKVL 140 E+LE R+P+ A L P+ G + ++ + + P N + + L + + Sbjct: 98 EWLEE-----RHPEPALLPPDLW--GRARVRALAEHVNSGTQPMQNALVLRMLREKVPGW 150 Query: 141 DNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIP 200 D +F G+ TLADC L+P+L+ + Sbjct: 151 DREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLDL------ 204 Query: 201 EAFRGVHRYLSNAYAREEFASTCPDDE 227 E + + R A F + PD + Sbjct: 205 EPYPTLRRVDEACAALAPFQAAHPDRQ 231 >5F05-A nrPDB Length = 212 Score = 47.8 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 34/166 (20%), Positives = 64/166 (38%), Gaps = 11/166 (6%) Query: 28 QRLFMVLWLKGVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFL 84 QR+ L+ K V F + V+ + + E L P GQ+P + G ++ I +++ Sbjct: 15 QRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYV 74 Query: 85 EAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL 144 +L A T + + + +P+ + + + + K + L Sbjct: 75 AHQYASKG-TQLGAAGNGYATILVWQEVESHQF----DPSASKLVWEQVFKPVFGLPTDA 129 Query: 145 TSPLPEEVDETSAEDE---GVSQRKFLDGNELTLADCNLLPKLHIV 187 EV D +SQ K+L + TLAD + LP + + Sbjct: 130 ALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHLPNIQAL 175 >2GLR-A nrPDB Length = 209 Score = 47.5 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 43/205 (20%), Positives = 73/205 (35%), Gaps = 21/205 (10%) Query: 27 SQRLFMVLWLKGVTFNVTTVDTKRRTETVQK-LCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 + + M+L +G ++ V + + K C GQLP G +N I L Sbjct: 14 CEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCLYGQLPKFEDGDLTLYQSNAILRHLG 73 Query: 86 AVLC-PPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL 144 L + + AA N D+ K+ I N E G +K L +L Sbjct: 74 RSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-------NYENGKNDYVKALPGHL 126 Query: 145 TSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFR 204 + + + F+ G++++ AD NLL L I QV+ F Sbjct: 127 K-------PFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLD-----NFP 174 Query: 205 GVHRYLSNAYAREEFASTCPDDEEI 229 + Y++ AR + + E + Sbjct: 175 LLSAYVARLSARPKIKAFLSSPEHV 199 >3PR8-A nrPDB Length = 229 Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 34/210 (16%), Positives = 70/210 (33%), Gaps = 8/210 (3%) Query: 32 MVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPP 91 + L KG+TF T + + + ++ P G++P L ++T+ I +++E Sbjct: 19 LALLEKGLTFEEVTFYGGQAPQAL-EVSPRGKVPVLETEHGFLSETSVILDYIEQTQGG- 76 Query: 92 RYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEE 151 L +P ++ + YI+ G+ ++ + L Sbjct: 77 --KALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVE-PLIKEKARADL--- 130 Query: 152 VDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLS 211 + + ++ G +LTLAD + + V KK F L Sbjct: 131 LAGFATLKRNGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDFLADFPQAKALLQ 190 Query: 212 NAYAREEFASTCPDDEEIELAYEQVAKALK 241 D E A+ ++ ++ K Sbjct: 191 LMGENPHMPRILADKEASMPAFMEMIRSGK 220 >5ZWP-A nrPDB Length = 208 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 61/185 (32%), Gaps = 39/185 (21%) Query: 22 GNCPFSQRLFMVLWLKGVTFNVTTVDTKR----RTETVQKLCPGGQLPFLLYGTEVHTDT 77 G+ P + + M G+ N ++ + + E K+ P +P L+ G ++ Sbjct: 8 GSAP-CRSVLMTAKALGIELNKKLLNLQAGEHLKPE-FLKINPQHTIPTLVDGDFALWES 65 Query: 78 NKIEEFLEAVLCPPRYPKLAALNPESNTAGLD--------IFAKFSAY----IKNSNPAL 125 I +L L P+ ++ F+ Y I PA Sbjct: 66 RAIMVYLVEKYGKTD--SLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPA- 122 Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 + L K + A L+ +L ++ G+ LT+AD LL + Sbjct: 123 DPELFKKIETAFDFLNTFLKGH------------------EYAAGDSLTVADLALLASVS 164 Query: 186 IVQVV 190 +V Sbjct: 165 TFEVA 169 >3LG6-A nrPDB Length = 235 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 25/191 (13%) Query: 27 SQRLFMVLWLKGVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEVHT-------- 75 S RL + LK + + V+ ++ ++T + L P +P L+ +T Sbjct: 21 SGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNTVSPSSASF 80 Query: 76 ---DTNKIEEFLEAVLCPPRYPKLAALNPESNTA----GLDIFAKFSAYIKNSNPALNDN 128 + E+LE L P L ++ A +I A + P N Sbjct: 81 SIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIAC------DVQPVTNLK 134 Query: 129 LEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQ 188 ++K +KAL + L + + +S +F G+E+TLAD L+P + + Sbjct: 135 IQK-KVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAAE 193 Query: 189 VVCKKYRGFTI 199 V F I Sbjct: 194 RVGMDLARFPI 204 >3BBY-A nrPDB Length = 215 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 40/91 (43%), Gaps = 5/91 (5%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKR----RTETVQKLCPGGQLPFLLYGTEVHTDTNK 79 P+ ++ L KG++F++ T+D + Q ++P L ++++ Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTW-QGYGQTRRVPLLQIDDFELSESSA 75 Query: 80 IEEFLEAVLCPPRYPKLAALNPESNTAGLDI 110 I E+LE PP + ++ L+ E+ I Sbjct: 76 IAEYLEDRFAPPTWERIYPLDLENRARARQI 106 >1U3I-A nrPDB Length = 211 Score = 44.4 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 32/206 (15%), Positives = 71/206 (34%), Gaps = 23/206 (11%) Query: 28 QRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT-----EVHTDTNKIEE 82 + + M L GV + + + + ++ PGG+LP + + ++ I Sbjct: 18 ESIRMTLVAAGVDYEDERISFQDWPK-IKPTIPGGRLPAVKVTDDHGHVKWMLESLAIAR 76 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDN 142 ++ ++ + + E + + + K L+K + + Sbjct: 77 YMAK-----KHHMMGETDEEYYSVEK---------LIGQAEDVEHEYHKTLMKPQEEKEK 122 Query: 143 YLTSPLPEEVDETSA---EDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTI 199 L +V E S K G+++TLAD L+ + V + K + Sbjct: 123 ITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLTGKY 182 Query: 200 PEAFRGVHRYLSNAYAREEFASTCPD 225 PE + L+++ ++ S P Sbjct: 183 PEIHKHRENLLASSPRLAKYLSNRPA 208 >18GS-A nrPDB Length = 210 Score = 44.0 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 40/167 (23%), Positives = 67/167 (40%), Gaps = 16/167 (9%) Query: 27 SQRLFMVLWLKGVTFNVTTVDTKRRTE-TVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 L M+L +G ++ V + E +++ C GQLP G +N I L Sbjct: 15 CAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLG 74 Query: 86 AVLC-PPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL 144 L + + AAL N D+ K+ + I + A D+ K L LK + L Sbjct: 75 RTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLL 134 Query: 145 TSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVC 191 + + + F+ G++++ AD NLL L I +V+ Sbjct: 135 S--------------QNQGGKTFIVGDQISFADYNLLDLLLIHEVLA 167 >6GZF-A nrPDB Length = 341 Score = 44.0 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 54/177 (30%), Gaps = 19/177 (10%) Query: 64 LPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFA-----KFSAYI 118 +P L E N+ EE + E +D++ K I Sbjct: 134 VPVLWDTEEDTIVNNESEEIMRMFDTEFD---------EFADHTVDLYPEGYQEKVDQII 184 Query: 119 KNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADC 178 N +N+ + + + E + D+ ++ +++L G+ LT AD Sbjct: 185 DNIYEPINNGVYRA---GFATEQEPYDEAVAELFGALAHWDDVLADQRYLAGDRLTEADI 241 Query: 179 NLLPKLHIVQ-VVCKKY-RGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAY 233 + L V + F + YL + Y A T D E Y Sbjct: 242 AMFTTLVRFDNVYHTHFMCNVQYIREFDNLWPYLRDLYQTHGIAETVEMDHITEHYY 298 >4MPF-A nrPDB Length = 266 Score = 43.6 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 22/159 (13%) Query: 38 GVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPR-- 92 G+ + TVD + +++ ++ G+LP L G + T+++ I +L P Sbjct: 47 GIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHW 106 Query: 93 YP-KLAALNPESNTAGLD---IFAKFS--AYIKNSNPALNDNLEKGLLKALK-VLDNYLT 145 YP L A G I F +++ P + + K ++ + +D L Sbjct: 107 YPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQ 166 Query: 146 SPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL 184 ED+ + R FL G ++TLAD L +L Sbjct: 167 ----------WLEDKFLGDRPFLAGQQVTLADLMALEEL 195 >6N0I-A nrPDB Length = 706 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 62/175 (35%), Gaps = 13/175 (7%) Query: 63 QLPFLLYGTEVH---TDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIK 119 +P L Y ++ D ++ + ++ L P A+ E N G K A Sbjct: 138 HVPRLAYINKMDRQGADFLRVVKQIDQRLGHHPVPIQLAIGSEENFMGQIDLVKMKAIYW 197 Query: 120 NSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCN 179 N E+ + LK L + + + E E + E KFLDG EL++ + Sbjct: 198 NDADQGTSYREEEIPAELKALADEWRAHMIEAAAEANDELTM----KFLDGEELSIEEIK 253 Query: 180 LLPKLHIV------QVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEE 228 + + ++ ++ +P V YL T PDDEE Sbjct: 254 AGLRQRTIANEIVPTILGSSFKNKGVPLMLDAVIDYLPAPSEIPAIRGTDPDDEE 308 >3M1G-A nrPDB Length = 362 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 158 EDEGVSQRKFLDGNELTLADCNLLPKLHIVQ-VVCKKYR-GFTIPEAFRGVHRYLSNAYA 215 ++ +S R++L G+ +T AD L P L V ++ G + YL + + Sbjct: 226 LEDRLSTRRYLMGDHITEADIRLYPTLVRFDAVYHGHFKCGRNKITEMPNLWGYLRDLFQ 285 Query: 216 REEFASTCPDDEEIELAYE 234 F T D EI+ Y Sbjct: 286 TPGFGDT-TDFTEIKQHYY 303 >2GDR-A nrPDB Length = 202 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 58/166 (34%), Gaps = 22/166 (13%) Query: 22 GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRT----ETVQKLCPGGQLPFL-LYGTEVHTD 76 G C S + L G+ F + VD + + ++ P G +P L L T+ Sbjct: 8 GACSLSPHI--ALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTE 65 Query: 77 TNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKF--SAYIKNSNPALNDNLEKGLL 134 I +++ + P + +LA N L + F S K+ +P N Sbjct: 66 GPAIVQYVADQV-PGK--QLAPANGSFERYHLQQWLNFISSELHKSFSPLFNPASS---- 118 Query: 135 KALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 D + + + +L G++L++AD L Sbjct: 119 ------DEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYL 158 >6F05-A nrPDB Length = 215 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 32/202 (15%), Positives = 68/202 (33%), Gaps = 9/202 (4%) Query: 28 QRLFMVLWLKGVTFNVTTVDTKR---RTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFL 84 +R + L KGV F VD + + L P G +P ++ G ++ + ++ Sbjct: 14 KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYV 73 Query: 85 EAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYL 144 P L E + L ++ + + + Sbjct: 74 AEKYRSQG-PDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLI 132 Query: 145 TSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKL-HIVQVVCKKYRGFTIPEAF 203 + + +S+ K+L G+ ++LAD LP ++V + K Y + + Sbjct: 133 KESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGPIGKAY----MIKDR 188 Query: 204 RGVHRYLSNAYAREEFASTCPD 225 + V + + +R + T Sbjct: 189 KHVSAWWDDISSRPAWKETVAK 210 >3IR4-A nrPDB Length = 218 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 36/183 (19%), Positives = 74/183 (40%), Gaps = 16/183 (8%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL-LYGTEVHTDTNKIE 81 +CPF + M+ LK + + + T ++ +P L + ++ I Sbjct: 11 HCPFCVKARMIFGLKNIPVELNVLQ-NDDEATPTRMIGQKMVPILQKDDSRYLPESMDIV 69 Query: 82 EFLEAVLCPP-----RYPKLAALNPESNTAGLDI----FAKFSAYIKNSNPALNDNLEKG 132 +++ + P R P + + N + FAK SA+ + S PA + Sbjct: 70 HYVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLLPRFAK-SAFDEFSTPAARQYFIRK 128 Query: 133 LLKALKVLDNYL--TSPLPEEV-DETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQV 189 + DN+L ++ L +++ D+ D+ + Q ++G L+ D +L P L + + Sbjct: 129 KEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGE-LSEDDIHLFPLLRNLTL 187 Query: 190 VCK 192 V Sbjct: 188 VAG 190 >1AXD-A nrPDB Length = 209 Score = 41.3 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 71/201 (35%), Gaps = 20/201 (9%) Query: 29 RLFMVLWLKGVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 R L G + + ++ + ++ P GQ+P L G ++ I ++ Sbjct: 16 RCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGDLYLFESRAICKYAA 75 Query: 86 AVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLL---KALKVLDN 142 P + E+ + I + + Y NP L L +L KV+D Sbjct: 76 RKNKPELLREGNLE--EAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDE 133 Query: 143 YLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRG--FTIP 200 L + + +++ K+L G+ L+LAD L+ V V + ++ Sbjct: 134 NL----EKLKKVLEVYEARLTKCKYLAGDFLSLAD------LNHVSVTLCLFATPYASVL 183 Query: 201 EAFRGVHRYLSNAYAREEFAS 221 +A+ V + S R Sbjct: 184 DAYPHVKAWWSGLMERPSVQK 204 >2CA8-A nrPDB Length = 211 Score = 40.9 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 72/207 (34%), Gaps = 25/207 (12%) Query: 28 QRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT-----EVHTDTNKIEE 82 + + M L GV + + + + ++ PGG+LP + + ++ I Sbjct: 18 ESIRMTLVAAGVNYEDERISFQDWPK-IKPTIPGGRLPAVKITDNHGHVKWMVESLAIAR 76 Query: 83 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKA----LK 138 ++ ++ + E + L K L+K K Sbjct: 77 YMAK-----KHHMMGGTEEEYYNVEK---------LIGQAEDLEHEYYKTLMKPEEEKQK 122 Query: 139 VLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFT 198 ++ L +P +D E S K G+++TLAD L+ + V + K++ Sbjct: 123 IIKEILNGKVPVLLD-IICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGK 181 Query: 199 IPEAFRGVHRYLSNAYAREEFASTCPD 225 PE + L+++ ++ S Sbjct: 182 YPEIHKHRENLLASSPRLAKYLSDRAA 208 >2PMT-A nrPDB Length = 203 Score = 40.9 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 67/170 (39%), Gaps = 30/170 (17%) Query: 22 GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRT----ETVQKLCPGGQLPFL-LYGTEVHTD 76 G+C S + VL G+ F++ +D + + + + P GQ+P L L ++ T+ Sbjct: 8 GSCSLSPHI--VLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTE 65 Query: 77 TNKIEEFLEA------VLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLE 130 I ++L ++ PP+ + N ++ +S + P Sbjct: 66 GVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSSDTP------- 118 Query: 131 KGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 ++YL + + ++ +S++K + G+ T+AD L Sbjct: 119 ----------ESYLPVVKNKLKSKFVYINDVLSKQKCVCGDHFTVADAYL 158 >2C3Q-A nrPDB Length = 247 Score = 40.1 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 25/165 (15%), Positives = 58/165 (35%), Gaps = 7/165 (4%) Query: 27 SQRLFMVLWLKGVTFNVTTVDT---KRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEF 83 + +++ + F + VD + ++ ++ P ++P L G T++ I + Sbjct: 21 CRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLY 80 Query: 84 LEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNS--NPALNDNLEKGLLKALKVLD 141 L P Y + ++ + A ++ S + + L Sbjct: 81 LTRKYKVPDY--WYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQ 138 Query: 142 NYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHI 186 + +V ED+ + + FL G ++LAD + +L Sbjct: 139 TLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMH 183 >6JWK-A nrPDB Length = 222 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 4/86 (4%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKR----RTETVQKLCPGGQLPFLLYGTEVHTDTN 78 N S R+ + L LKG+ + V V+ ++ R Q+ G + + + Sbjct: 8 NSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSL 67 Query: 79 KIEEFLEAVLCPPRYPKLAALNPESN 104 I ++L+AV PR L L+ Sbjct: 68 AIIDYLDAVQPEPRLIPLDPLHRAQA 93 >4PXO-A nrPDB Length = 238 Score = 39.4 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 52/158 (32%), Gaps = 7/158 (4%) Query: 29 RLFMVLWLKGVTFNVTTVDT----KRRTETVQKLCPGGQLPFLLYGT-EVHTDTNKIEEF 83 R+ + L LKG+ + +D + + + P G +P L G T + I ++ Sbjct: 37 RVRIALNLKGIAYEEVFLDLDAGDQHKP-DFLAINPQGAVPALFDGDGPPLTQSLAILDY 95 Query: 84 LEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNY 143 LE + + A + + GL + ++L+ Sbjct: 96 LEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMENYGLPRE-RMLEFL 154 Query: 144 LTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLL 181 + + + +F G+ ++ AD L+ Sbjct: 155 RNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLI 192 >4PTS-A nrPDB Length = 348 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 38/245 (15%), Positives = 77/245 (31%), Gaps = 44/245 (17%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTV---DTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNK 79 CP++ R +V L G+ ++ T + L PGG P L + Sbjct: 55 ACPWANRTLIVRRLLGLENVLSLGLCGPTHDKNSWTFDLDPGGVDPVLGIPRL----KDA 110 Query: 80 IEEFLEAVLCPPRYPK----LAALNPESNTAGLDIFAKFSA-YIKNSNPALNDNLEKGLL 134 E+ P YPK A + + + F + + + D + Sbjct: 111 YEKRF------PGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAPQLYP 164 Query: 135 KALKVLDNYLTSPLPEEVD------------------------ETSAEDEGVSQRKFLDG 170 + L+ + ++ + EV+ + E ++Q+++L G Sbjct: 165 EHLRAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQRYLVG 224 Query: 171 NELTLADCNLLPKLHIVQ-VVCKKYR-GFTIPEAFRGVHRYLSNAYAREEFASTCPDDEE 228 + +T AD L L V ++ + + Y + + F T + Sbjct: 225 DTITEADVRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGFGDTTDFTQI 284 Query: 229 IELAY 233 + Y Sbjct: 285 KQHYY 289 >1F2E-A nrPDB Length = 201 Score = 35.5 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 50/155 (32%), Gaps = 18/155 (11%) Query: 32 MVLWLKGVTFNVTTVDTKRRT----ETVQKLCPGGQLPFLLYG-TEVHTDTNKIEEFLEA 86 + L G F VD R E + P G++P L E T+ I ++ Sbjct: 16 IALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIAD 75 Query: 87 VLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPA-LNDNLEKGLLKALKVLDNYLT 145 A + + + S + K P ++ A + + N+L Sbjct: 76 QNPASGL-APAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNHLA 134 Query: 146 SPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180 + D+ ++ R GN ++AD L Sbjct: 135 A-----------LDKELAGRDHYAGNAFSVADIYL 158 >4USS-A nrPDB Length = 325 Score = 34.7 bits (78), Expect = 0.031, Method: Composition-based stats. Identities = 37/253 (14%), Positives = 78/253 (30%), Gaps = 47/253 (18%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQK---------LCPGGQLPFLLYGTEV 73 CP++ R L +KG+ + + + + P + + Sbjct: 48 ACPWASRCLAYLKIKGLEKAIAFTSV--KPIWERTKESDEHMGWVFPASETEEAGAEPDT 105 Query: 74 HTDTNKIEEFLE--AVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEK 131 I E E + +Y + + T + + S I+ N ND E Sbjct: 106 LNGARSIRELYELASTNYAGKYTVPVLWDKKLKTIVNN---ESSEIIRMFNTEFNDIAEN 162 Query: 132 GLLK----ALKV-LDN-----------------YLTSPLPEE------VDETSAEDEGVS 163 L L+ +D + P E + +E + Sbjct: 163 AALDLYPSHLQAQIDETNGWVYDGINNGVYKCGFARKQGPYEEAAIQLYEALDKCEEILG 222 Query: 164 QRKFLDGNELTLADCNLLPKLHIV-QVVCKKYR-GFTIPEAFRGVHRYLSNAYAREEFAS 221 +++++ GN L+ AD L L +V ++ + + + Y + + +S Sbjct: 223 RQRYICGNTLSEADIKLFVTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMSS 282 Query: 222 TCPDDEEIELAYE 234 T + + I+ Y Sbjct: 283 TV-NMQHIKRHYY 294 >2PPQ-A nrPDB Length = 322 Score = 34.7 bits (78), Expect = 0.031, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 27/57 (47%) Query: 118 IKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELT 174 + + + D +EKGL + ++ +YL + P+++ + F G+EL+ Sbjct: 151 LWDKSEERADEVEKGLREEIRPEIDYLAAHWPKDLPAGVIHADLFQDNVFFLGDELS 207 >4FN5-A nrPDB Length = 709 Score = 34.7 bits (78), Expect = 0.032, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 55/163 (33%), Gaps = 12/163 (7%) Query: 75 TDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLL 134 + ++ E ++ L P A+ E N G K A N + E+ + Sbjct: 152 ANFLRVVEQIKKRLGHTPVPVQLAIGAEENFVGQVDLIKMKAIYWNDDDKGMTYREEEIP 211 Query: 135 KALKVLDNYLTSPLPEEVDETSA-------EDEGVSQRKFLDGNELTLADCNLLPKLHIV 187 LK L S + E E + E+ +S+ + +G L C ++P Sbjct: 212 AELKDLAEEWRSSMVEAAAEANEELMNKYLEEGELSEAEIKEGLRLRTLACEIVPA---- 267 Query: 188 QVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIE 230 V ++ +P V YL PDDE +E Sbjct: 268 -VCGSSFKNKGVPLVLDAVIDYLPAPTEIPAIKGVSPDDETVE 309 >6GCB-A nrPDB Length = 325 Score = 34.0 bits (76), Expect = 0.064, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 46/117 (39%), Gaps = 8/117 (6%) Query: 126 NDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 N+ + K + PL E +D ++ ++ + +L G++LT AD L + Sbjct: 189 NNGVYKAGFATTQQAYEAAVIPLFESLDRL---EKILTGKDYLVGDQLTEADVRLFVTII 245 Query: 186 IVQVV-CKKYRG--FTIPEAFRGVHRYLSNAY-AREEFASTCPDDEEIELAYEQVAK 238 ++ TI + + +H +L Y F+ TC D I+ +Y Sbjct: 246 RFDPAYVGHFKCNLRTIRDGYPAIHLWLRKLYWNNSAFSETCKFD-HIKASYYAQKN 301 >2PBJ-A nrPDB Length = 290 Score = 32.8 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 46/130 (35%), Gaps = 21/130 (16%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLL----YGTEVHTDTNK 79 CPF ++ L + + V V+ R E K ++P L+ ++ D++ Sbjct: 23 CPFCSKVRAFLDFHALPYQVVEVNPVLRAE--IKFSSYRKVPILVAQEGESSQQLNDSSV 80 Query: 80 IEEFLEAVLCPPR--------YPKLAALN---PESNTAGLDIFAKFSAYIKNSNPALNDN 128 I L+ L + YP + A+N E G K+ + + Sbjct: 81 IISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGN----KYWLMLNEKEAQQVYS 136 Query: 129 LEKGLLKALK 138 ++ + +K Sbjct: 137 GKEARTEEMK 146 >4MDC-A nrPDB Length = 252 Score = 32.4 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 24/177 (13%), Positives = 57/177 (32%), Gaps = 8/177 (4%) Query: 24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT-EVHTDTNKIEE 82 P S+ + ++L G ++ L P G LP + + I E Sbjct: 32 SPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCGATIISE 91 Query: 83 FLEAVLCPPRYP-KLAALNPESNTAGLDIFAKFSAYIKN--SNPALNDNLEKGLLKALK- 138 +L+ + +L A +P + F ++ + P + + + K + + Sbjct: 92 YLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRERIFKLQMTPDQG 151 Query: 139 --VLDNY-LTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCK 192 D+ L + R +L G+ ++ D + ++ + + Sbjct: 152 GGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAAAISVLDYLGE 208 >1G6W-A nrPDB Length = 261 Score = 32.0 bits (71), Expect = 0.21, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 14/98 (14%) Query: 130 EKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLD------GNELTLADCNLLPK 183 E L + + L L + E SA +SQ +F D G++LT+AD +P Sbjct: 167 EMALAERREALVMELDT---ENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPW 223 Query: 184 LHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAS 221 ++V + G I F V+++ + R Sbjct: 224 NNVVDRI-----GINIKIEFPEVYKWTKHMMRRPAVIK 256 >3M8N-A nrPDB Length = 225 Score = 31.3 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 56/176 (31%), Gaps = 21/176 (11%) Query: 27 SQRLFMVLWLKGVTFNVTTVDTKR---RTETVQKLCPGGQLPFL-LYGTEVHTDTNKIEE 82 S ++ + L L + VD R RT P GQ+P L ++N I Sbjct: 15 SYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAPGRYLAESNAILW 74 Query: 83 FLE--AVLCPPRYPK--------LAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKG 132 +L L P + G F + +K LE Sbjct: 75 YLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYF--WLCLVKGGRDLQTHALEDW 132 Query: 133 LLK---ALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLH 185 L + AL+V++N+L + + + D + + D + P ++ Sbjct: 133 LERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQ--CDFDLSTFPAVN 186 >4LMW-A nrPDB Length = 251 Score = 30.9 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 36/237 (15%), Positives = 79/237 (33%), Gaps = 31/237 (13%) Query: 15 GSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKL-CPGGQ---------- 63 ++ ++ P + + VL KG+ + V+ +++ P + Sbjct: 13 ANEPRQMAWGPNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYT 72 Query: 64 LPFLLYGTE--VHTDTNKIEEFLEAVLC--PPRYPK--------------LAALNPESNT 105 LP + V D++ I ++LE+ P +P+ + L P N Sbjct: 73 LPVIQDPNTKAVVADSDAIAKYLESTYPDTPRLFPEGTRAFQHAFYQLARPSVLMPIFNI 132 Query: 106 AGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQR 165 ++ + A + + L+ + D++ ++S E G + Sbjct: 133 VVARVWKLLRPRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKD 192 Query: 166 KFLDGNELTLADCNLLPKLHIVQV-VCKKYRGFTIPEAF-RGVHRYLSNAYAREEFA 220 L G+ +T AD L ++V ++ + + G +A EF Sbjct: 193 LLLMGDRVTFADLQLASLFIWLRVSAGEESEDWKRFLSLHEGKWAKFMQQFAAYEFV 249 >2PVQ-A nrPDB Length = 201 Score = 30.9 bits (68), Expect = 0.48, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 47/125 (37%), Gaps = 11/125 (8%) Query: 32 MVLWLKGVTFNVTTVDTKRRTE----TVQKLCPGGQLPFL-LYGTEVHTDTNKIEEFL-- 84 ++L G+ + + VD K + + P G +P L + V T I +++ Sbjct: 16 IILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPGTVITQNAAILQYIGD 75 Query: 85 --EAVLCPPRYPKLA-ALNPESNTAGLDIFAKFS-AYIKNSNPALNDNLEKGLLKALKVL 140 + P Y + A E+ D+ A FS + N + + + + L L Sbjct: 76 HSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANINRRLGQL 135 Query: 141 DNYLT 145 + L+ Sbjct: 136 EAMLS 140 >4FQU-A nrPDB Length = 313 Score = 30.5 bits (67), Expect = 0.61, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 52/140 (37%), Gaps = 22/140 (15%) Query: 64 LPFL---LYGTEVHTDTNKIEEFL----EAVLCPPRYPKLAALNPESNTAGLDIFAKFSA 116 +P L + ++ ++++I L + V P A PE + ++ Sbjct: 122 IPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVY----- 176 Query: 117 YIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLA 176 LN+ + + + PL + +D +E ++ R++L G+ LT A Sbjct: 177 ------ETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWL---EEHLTGREWLVGDRLTEA 227 Query: 177 DCNLLPKLHIVQVVC-KKYR 195 D L P L + ++ Sbjct: 228 DIRLFPTLVRFDAIYHGHFK 247 >2WDU-A nrPDB Length = 211 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 58/183 (31%), Gaps = 29/183 (15%) Query: 30 LFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT-----EVHTDTNKIEEFL 84 + ++L GV F + T++ PGG++P L + ++ I L Sbjct: 20 IRLLLTCAGVKFEDYQFTMDQWP-TIKPTLPGGRVPLLDVTGPDGKLRRYQESMAIARLL 78 Query: 85 EAVLCPPRYPKLAALNPESNTA------GLDIFAKFSAYIKNSNPALNDNLEKGLLKALK 138 ++ + + E D++ + + ++ +K K Sbjct: 79 AR-----QFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQ-----GEKEAKIKEFK 128 Query: 139 VLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFT 198 + + + +E S K + GN +TL D L L V + Sbjct: 129 ENNG-------PTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPGFLEQK 181 Query: 199 IPE 201 P+ Sbjct: 182 FPK 184 >3A58-B nrPDB Length = 188 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 46 VDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLE 85 VD + +T+++L GQ P + D + E Sbjct: 124 VDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYE 163 >6A94-A nrPDB Length = 376 Score = 29.3 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 10/28 (35%) Query: 197 FTIPEAFRGVHRYLSNAYAREEFASTCP 224 + +P V YL ++ + C Sbjct: 75 WPLPSKLCAVWIYLDVLFSTAKIWHLCA 102 >3QMX-A nrPDB Length = 99 Score = 29.0 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%) Query: 12 VKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVD 47 V A + CPF R +L KGV F +D Sbjct: 14 VSAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCID 49 >2KLX-A nrPDB Length = 89 Score = 28.2 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 21/49 (42%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGT 71 NCP+ +R +L KGV + T R E VQ+ P + G Sbjct: 15 NCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFPQIFIGD 63 >3DKB-A nrPDB Length = 390 Score = 28.2 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 14/33 (42%), Gaps = 3/33 (9%) Query: 199 IPEAFRGVHRYLSNAYAREEFASTCPDDEEIEL 231 I F+ +HRY + +F CP EI Sbjct: 56 IIHHFKTMHRYTLEMFRTCQF---CPQFREIIH 85 >1QP8-A nrPDB Length = 303 Score = 27.8 bits (60), Expect = 4.5, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 20/51 (39%), Gaps = 3/51 (5%) Query: 172 ELTLADCNLLPKLHIVQV--VCKKYRGFT-IPEAFRGVHRYLSNAYAREEF 219 +T + +P+L +QV + + IP SNA A EF Sbjct: 39 RITAEELAKMPRLKFIQVVTAGLDHLPWESIPPHVTVAGNAGSNADAVAEF 89 >5WJC-B nrPDB Length = 112 Score = 27.4 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 10/77 (12%), Positives = 33/77 (42%), Gaps = 7/77 (9%) Query: 129 LEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQ 188 LEK + + + + +P+ + + A + + +R+F+ P+++ + Sbjct: 6 LEKARAIEIAFDNVFHNTKIPDNLQQFDAILKRLERRRFIPTENQK-------PRVYETE 58 Query: 189 VVCKKYRGFTIPEAFRG 205 ++ ++R F + + Sbjct: 59 LLVLRFREFGVKDNHNH 75 >6F4A-B nrPDB Length = 644 Score = 27.4 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 24/180 (13%), Positives = 49/180 (27%), Gaps = 43/180 (23%) Query: 23 NCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEE 82 +C +Q + + G +V +VD E + KI Sbjct: 119 DCILNQEIIPSMLNTGTDDSVHSVDFSNPAEWF-------------------PEARKIRR 159 Query: 83 FLEAVLCPPRYPKLA--ALNPESNTAG----------LDIFAKFS------------AYI 118 + + P K ++ G +++ KF I Sbjct: 160 HIIMHVGPTNSGKTFRSLQKLKAADRGYYAGPLRLLAREVYEKFKHENVRCNLLTGEEVI 219 Query: 119 KNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADC 178 K+ + N+ + L+ + +E+ + D G + L G + C Sbjct: 220 KDLDEMGNEANLTSGTIEMIPLNQNFDVVVLDEIQMMADLDRGWAWTNALLGAKAKEVHC 279 >3J6D-a nrPDB Length = 252 Score = 27.0 bits (58), Expect = 8.1, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 34/84 (40%) Query: 132 GLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVC 191 L+ + + L S + + ++++ EGV + ++ + PK + + Sbjct: 93 SLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALA 152 Query: 192 KKYRGFTIPEAFRGVHRYLSNAYA 215 RG + + R+L N++A Sbjct: 153 VYERGSPLAHQISDIKRFLKNSFA 176 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.126 0.323 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,408,322 Number of Sequences: 36641 Number of extensions: 311108 Number of successful extensions: 981 Number of sequences better than 10.0: 89 Number of HSP's better than 10.0 without gapping: 70 Number of HSP's successfully gapped in prelim test: 58 Number of HSP's that attempted gapping in prelim test: 840 Number of HSP's gapped (non-prelim): 133 length of query: 241 length of database: 10,336,785 effective HSP length: 94 effective length of query: 147 effective length of database: 6,892,531 effective search space: 1013202057 effective search space used: 1013202057 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.6 bits)