BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= B8Y6I0 (786 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4M57-A nrPDB 1494 0.0 6GAW-Ao nrPDB 47 2e-05 6GAZ-Ao nrPDB 45 8e-05 5G05-C nrPDB 44 2e-04 4LEU-A nrPDB 41 0.002 3NF1-A nrPDB 39 0.012 6FUZ-A nrPDB 38 0.013 6HIW-DH nrPDB 37 0.031 5OJ8-A nrPDB 36 0.056 5OJF-A nrPDB 35 0.097 3ZFW-A nrPDB 35 0.11 6GAZ-Ae nrPDB 35 0.12 3JD5-e nrPDB 34 0.26 2YFT-A nrPDB 34 0.27 3H4S-A nrPDB 33 0.41 3DV0-B nrPDB 33 0.70 6E85-A nrPDB 32 1.00 5YJE-A nrPDB 32 1.2 6HIX-BI nrPDB 32 1.3 4UZY-A nrPDB 31 2.0 5CQS-A nrPDB 30 2.9 6HIW-DG nrPDB 30 6.0 2ZIV-A nrPDB 29 6.4 4IFS-A nrPDB 29 8.0 4ME2-A nrPDB 29 8.7 4P7A-A nrPDB 29 9.7 >4M57-A nrPDB Length = 726 Score = 1494 bits (3869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 722/726 (99%), Positives = 722/726 (99%) Query: 61 SHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHW 120 SHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHW Sbjct: 1 SHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHW 60 Query: 121 EWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTV 180 EWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTV Sbjct: 61 EWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTV 120 Query: 181 LHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAG 240 LHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAG Sbjct: 121 LHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAG 180 Query: 241 VEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEAL 300 VEPDGFTASTVIAAC RDGLVDEAVAFFEDLKARGHAP VVTYNALLQVFGKAGNYTEAL Sbjct: 181 VEPDGFTASTVIAACSRDGLVDEAVAFFEDLKARGHAPSVVTYNALLQVFGKAGNYTEAL 240 Query: 301 RVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAY 360 RVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAY Sbjct: 241 RVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAY 300 Query: 361 GNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNR 420 GNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNR Sbjct: 301 GNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNR 360 Query: 421 VTWNTMLAVCGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNE 480 VTWNTMLAV GKRGMEDYVTRVLEGMRS GVELSRDTYNTLIAAYGRCGSRTNAFKMYNE Sbjct: 361 VTWNTMLAVSGKRGMEDYVTRVLEGMRSSGVELSRDTYNTLIAAYGRCGSRTNAFKMYNE 420 Query: 481 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN 540 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN Sbjct: 421 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN 480 Query: 541 VAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFN 600 VAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFN Sbjct: 481 VAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFN 540 Query: 601 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCS 660 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCS Sbjct: 541 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCS 600 Query: 661 QTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSE 720 QTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSE Sbjct: 601 QTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSE 660 Query: 721 AREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIE 780 AREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIE Sbjct: 661 AREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIE 720 Query: 781 DAQFGR 786 DAQFGR Sbjct: 721 DAQFGR 726 >6GAW-Ao nrPDB Length = 692 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/263 (21%), Positives = 113/263 (42%), Gaps = 45/263 (17%) Query: 477 MYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYA 536 M++++ AG T + T N+LL++L G+ + + + R + + E + + + Sbjct: 172 MFDQLLQAGTTVSLETTNSLLDLLCYYGNQEPSANYNFQQREQSEELEEATEADNEKSKT 231 Query: 537 KGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDL 596 K G+ G+ +W R + E F + + + Sbjct: 232 KAGHHLGV---------------TW-------------RTKNNAERIFALMPEKNAHS-- 261 Query: 597 VIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYA-----KCSESWEAE 651 + +M+ K+ ++A ++ + + L D+ T+NSL++ A K E W Sbjct: 262 --YCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWN-- 317 Query: 652 KILNQLK--CSQTMKPDVVSYNTVIN---GFCKQGLVKEAQRVLSEMVADGMAPCAVTYH 706 IL+ LK +Q +KP++ ++NT++ F G + A + L EM A G+ P TYH Sbjct: 318 NILDLLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKLP-ALQTLREMKAIGIEPSLATYH 376 Query: 707 TLVGGYSSLEMFSEAREVIGYMV 729 ++ + E S+ +I Y + Sbjct: 377 YVIQLFYQHESPSKGSSLIIYDI 399 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 54/250 (21%), Positives = 102/250 (40%), Gaps = 27/250 (10%) Query: 261 VDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGEMEQNGCQPDAVTYNE 320 V +V F+ L G + T N+LL + GN + + + + + T + Sbjct: 166 VKASVDMFDQLLQAGTTVSLETTNSLLDLLCYYGNQEPSANYNFQQREQSEELEEATEAD 225 Query: 321 LAGTYARAGFF--------EEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALAL 372 + +AG A R M K NA +Y T++ +AL L Sbjct: 226 NEKSKTKAGHHLGVTWRTKNNAERIFALMPEK----NAHSYCTMIRGMVKHQAPTQALNL 281 Query: 373 FDQMKKTGFVPNVNTYNLVLG----MLGKK--SRFTVMLEMLGEMSRSGCTPNRVTWNTM 426 + + +V T+N ++ ++ +K ++ +L++L +M PN T+NT+ Sbjct: 282 YTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTI 341 Query: 427 LAVCGKRGM---EDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRC-----GSRTNAFKMY 478 L C +R + + L M++ G+E S TY+ +I + + GS + + Sbjct: 342 LK-CLRRFYAFGKLPALQTLREMKAIGIEPSLATYHYVIQLFYQHESPSKGSSLIIYDIM 400 Query: 479 NEMTSAGFTP 488 NE+ F+P Sbjct: 401 NEVMGKRFSP 410 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Query: 173 DVRAYTTVLHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLD-----VYGRMGRSWP 227 + +Y T++ + + +AL L+ L + + T+N +++ V + W Sbjct: 258 NAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWN 317 Query: 228 RIVALLDEMRAAGVEPDGFTASTVIAACCRDGLVDE--AVAFFEDLKARGHAPCVVTYNA 285 I+ LL +M V+P+ T +T++ R + A+ ++KA G P + TY+ Sbjct: 318 NILDLLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKLPALQTLREMKAIGIEPSLATYHY 377 Query: 286 LLQVF 290 ++Q+F Sbjct: 378 VIQLF 382 Score = 37.0 bits (84), Expect = 0.037, Method: Compositional matrix adjust. Identities = 37/186 (19%), Positives = 80/186 (43%), Gaps = 22/186 (11%) Query: 365 KVDEALALFDQMKKTGFVPNVNTYNLVLGML---GKKS-------RFTVMLEMLGEMSRS 414 KV ++ +FDQ+ + G ++ T N +L +L G + + E L E + + Sbjct: 165 KVKASVDMFDQLLQAGTTVSLETTNSLLDLLCYYGNQEPSANYNFQQREQSEELEEATEA 224 Query: 415 GCTPNRVTWNTMLAVCGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNA 474 ++ L V + ++ R+ M E + +Y T+I + + T A Sbjct: 225 DNEKSKTKAGHHLGVTWR--TKNNAERIFALM----PEKNAHSYCTMIRGMVKHQAPTQA 278 Query: 475 FKMYNEMTSAGFTPCITTYNALLNVLSR------QGDWSTAQSIVSKMRTKGFKPNEQSY 528 +Y + + + T+N+L+ + + W+ ++ +M T+ KPN Q++ Sbjct: 279 LNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTF 338 Query: 529 SLLLQC 534 + +L+C Sbjct: 339 NTILKC 344 Score = 36.6 bits (83), Expect = 0.047, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 22/130 (16%) Query: 171 RLDVRAYTTVLHALSRA------GRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGR 224 R DV + +++ A + ++ L+L ++ Q V P L T+N +L R Sbjct: 291 RADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTILKCLRRF-Y 349 Query: 225 SWPRIVAL--LDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVT 282 ++ ++ AL L EM+A G+EP T VI F ++ ++ Sbjct: 350 AFGKLPALQTLREMKAIGIEPSLATYHYVI-------------QLFYQHESPSKGSSLII 396 Query: 283 YNALLQVFGK 292 Y+ + +V GK Sbjct: 397 YDIMNEVMGK 406 >6GAZ-Ao nrPDB Length = 692 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 13/139 (9%) Query: 601 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYA-----KCSESWEAEKILN 655 +M+ K+ ++A ++ + + L D+ T+NSL++ A K E W IL+ Sbjct: 264 TMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWN--NILD 321 Query: 656 QLK--CSQTMKPDVVSYNTVIN---GFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVG 710 LK +Q +KP++ ++NT++ F G + Q L EM A G+ P TYH ++ Sbjct: 322 LLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKLPALQ-TLREMKAIGIEPSLATYHYVIQ 380 Query: 711 GYSSLEMFSEAREVIGYMV 729 + E S+ +I Y + Sbjct: 381 LFYQHESPSKGSSLIIYDI 399 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Query: 173 DVRAYTTVLHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLD-----VYGRMGRSWP 227 + +Y T++ + + +AL L+ L + + T+N +++ V + W Sbjct: 258 NAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWN 317 Query: 228 RIVALLDEMRAAGVEPDGFTASTVIAACCRDGLVDE--AVAFFEDLKARGHAPCVVTYNA 285 I+ LL +M V+P+ T +T++ R + A+ ++KA G P + TY+ Sbjct: 318 NILDLLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKLPALQTLREMKAIGIEPSLATYHY 377 Query: 286 LLQVF 290 ++Q+F Sbjct: 378 VIQLF 382 Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust. Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 19/168 (11%) Query: 282 TYNALLQVFGKAGNYTEALRVLGEMEQNGCQPDAVTYNELAGTYA---RAGFFEEAARCL 338 +Y +++ K T+AL + + N + D T+N L A F E+ L Sbjct: 261 SYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWNNIL 320 Query: 339 D---TMASKGLLPNAFTYNTVMTA---YGNVGKVDEALALFDQMKKTGFVPNVNTYNLVL 392 D M ++ + PN T+NT++ + GK+ AL +MK G P++ TY+ V+ Sbjct: 321 DLLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKL-PALQTLREMKAIGIEPSLATYHYVI 379 Query: 393 GMLGKKSR---------FTVMLEMLGEMSRSGCTPNRVTWNTMLAVCG 431 + + + +M E++G+ + + + + + VC Sbjct: 380 QLFYQHESPSKGSSLIIYDIMNEVMGKRFSPRDPDDDMFFQSAMRVCS 427 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 74/160 (46%), Gaps = 17/160 (10%) Query: 345 GLLP--NAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVLG----MLGKK 398 L+P NA +Y T++ +AL L+ + +V T+N ++ ++ +K Sbjct: 252 ALMPEKNAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEK 311 Query: 399 --SRFTVMLEMLGEMSRSGCTPNRVTWNTMLAVCGKRGM---EDYVTRVLEGMRSCGVEL 453 ++ +L++L +M PN T+NT+L C +R + + L M++ G+E Sbjct: 312 FEEKWNNILDLLKQMVTQNVKPNLQTFNTILK-CLRRFYAFGKLPALQTLREMKAIGIEP 370 Query: 454 SRDTYNTLIAAYGRC-----GSRTNAFKMYNEMTSAGFTP 488 S TY+ +I + + GS + + NE+ F+P Sbjct: 371 SLATYHYVIQLFYQHESPSKGSSLIIYDIMNEVMGKRFSP 410 Score = 36.2 bits (82), Expect = 0.053, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 22/130 (16%) Query: 171 RLDVRAYTTVLHALSRA------GRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGR 224 R DV + +++ A + ++ L+L ++ Q V P L T+N +L R Sbjct: 291 RADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTILKCLRRF-Y 349 Query: 225 SWPRIVAL--LDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVT 282 ++ ++ AL L EM+A G+EP T VI F ++ ++ Sbjct: 350 AFGKLPALQTLREMKAIGIEPSLATYHYVI-------------QLFYQHESPSKGSSLII 396 Query: 283 YNALLQVFGK 292 Y+ + +V GK Sbjct: 397 YDIMNEVMGK 406 Score = 36.2 bits (82), Expect = 0.061, Method: Compositional matrix adjust. Identities = 19/89 (21%), Positives = 43/89 (48%), Gaps = 6/89 (6%) Query: 452 ELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSR------QGD 505 E + +Y T+I + + T A +Y + + + T+N+L+ + + Sbjct: 256 EKNAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEK 315 Query: 506 WSTAQSIVSKMRTKGFKPNEQSYSLLLQC 534 W+ ++ +M T+ KPN Q+++ +L+C Sbjct: 316 WNNILDLLKQMVTQNVKPNLQTFNTILKC 344 >5G05-C nrPDB Length = 597 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 22/95 (23%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 321 LAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTG 380 LA Y EEA + + G +++ + + AY N+ +D+AL++F++++K Sbjct: 234 LAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD 293 Query: 381 --FVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSR 413 + N++T++ +L + KS + + L E+ + Sbjct: 294 PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328 >4LEU-A nrPDB Length = 257 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 2/98 (2%) Query: 615 ATEVFDSI-KRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTV 673 A ++F+ I K+ PD+ Y L+ AK EA + ++K + + PD +Y V Sbjct: 126 AIKMFEVIQKQEWYQPDVFMYKDLIVSLAKSKRMDEAMALWEKMK-KENLFPDSQTYTEV 184 Query: 674 INGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGG 711 I GF + G +A V +M+ P + + L+ G Sbjct: 185 IRGFLRDGCPADAMNVYEDMLKSPDPPEELPFRVLLKG 222 Score = 37.0 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 1/90 (1%) Query: 307 EQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKV 366 +Q QPD Y +L + A++ +EA + M + L P++ TY V+ + G Sbjct: 135 KQEWYQPDVFMYKDLIVSLAKSKRMDEAMALWEKMKKENLFPDSQTYTEVIRGFLRDGCP 194 Query: 367 DEALALFDQMKKTGFVPNVNTYNLVL-GML 395 +A+ +++ M K+ P + ++L G+L Sbjct: 195 ADAMNVYEDMLKSPDPPEELPFRVLLKGLL 224 Score = 35.4 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 21/115 (18%) Query: 242 EPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALR 301 +PD F +I + + +DEA+A +E +K P TY +++ F + G +A+ Sbjct: 140 QPDVFMYKDLIVSLAKSKRMDEAMALWEKMKKENLFPDSQTYTEVIRGFLRDGCPADAMN 199 Query: 302 VLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTV 356 V +M ++ P+ + + L KGLLP+ N V Sbjct: 200 VYEDMLKSPDPPEELPFRVLL---------------------KGLLPHPLLRNKV 233 Score = 33.1 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 5/119 (4%) Query: 171 RLDVRAYTTVLHALSRAGRYERALELFAELRRQG-VAPTLVTYNVVLDVYGRMGRSWPRI 229 +LD+ A V+ L R A+++F +++Q P + Y ++ + R Sbjct: 107 KLDMLA---VIGELERQEETALAIKMFEVIQKQEWYQPDVFMYKDLIVSLAKSKR-MDEA 162 Query: 230 VALLDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQ 288 +AL ++M+ + PD T + VI RDG +A+ +ED+ P + + LL+ Sbjct: 163 MALWEKMKKENLFPDSQTYTEVIRGFLRDGCPADAMNVYEDMLKSPDPPEELPFRVLLK 221 Score = 30.4 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 40/80 (50%) Query: 559 PSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEV 618 P + + L+++ K +R+D ++++K PD + ++ + ++G + A V Sbjct: 141 PDVFMYKDLIVSLAKSKRMDEAMALWEKMKKENLFPDSQTYTEVIRGFLRDGCPADAMNV 200 Query: 619 FDSIKRSGLSPDLITYNSLM 638 ++ + +S P+ + + L+ Sbjct: 201 YEDMLKSPDPPEELPFRVLL 220 >3NF1-A nrPDB Length = 311 Score = 38.5 bits (88), Expect = 0.012, Method: Compositional matrix adjust. Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 35/175 (20%) Query: 231 ALLDEMRAAGVE-PDGFTASTVIAACCRD--------GLVDEAVAFFEDLKARGHAPCVV 281 AL D + +G + PD T ++A RD L+++A+A E + H Sbjct: 53 ALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAA 112 Query: 282 TYNALLQVFGKAGNYTEA-----------LRVLGEMEQNGCQPD-AVTYNELAGTYARAG 329 T N L ++GK G Y EA +VLG+ PD A N LA G Sbjct: 113 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD-----HPDVAKQLNNLALLCQNQG 167 Query: 330 FFEEA----ARCLDTMASKGLLPN----AFTYNTVMTAYGNVGKVDEALALFDQM 376 +EE R L+ +K L P+ A T N + + Y GK +A L+ ++ Sbjct: 168 KYEEVEYYYQRALEIYQTK-LGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEI 221 >6FUZ-A nrPDB Length = 337 Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust. Identities = 50/175 (28%), Positives = 72/175 (41%), Gaps = 35/175 (20%) Query: 231 ALLDEMRAAGVE-PDGFTASTVIAACCRD--------GLVDEAVAFFEDLKARGHAPCVV 281 AL D + +G + PD T ++A RD L+++A+A E R H Sbjct: 39 ALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAA 98 Query: 282 TYNALLQVFGKAGNYTEA-----------LRVLGEMEQNGCQPD-AVTYNELAGTYARAG 329 T N L ++GK G Y EA +VLG+ PD A N LA G Sbjct: 99 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD-----HPDVAKQLNNLALLCQNQG 153 Query: 330 FFEEA----ARCLDTMASKGLLPN----AFTYNTVMTAYGNVGKVDEALALFDQM 376 +EE R L +K L P+ A T N + + Y GK +A L+ ++ Sbjct: 154 KYEEVEYYYQRALGIYQTK-LGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEI 207 >6HIW-DH nrPDB Length = 581 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 28/42 (66%) Query: 477 MYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRT 518 +Y+ M S G +P I+TY ++ LS QG+ A+SI+S +R+ Sbjct: 229 VYDRMGSMGISPTISTYELVMLALSLQGNMVEAESILSFLRS 270 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 30/59 (50%) Query: 618 VFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTVING 676 V+D + G+SP + TY +M + EAE IL+ L+ + V S+N ++ G Sbjct: 229 VYDRMGSMGISPTISTYELVMLALSLQGNMVEAESILSFLRSHHSEHITVESFNALLLG 287 >5OJ8-A nrPDB Length = 255 Score = 36.2 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 35/175 (20%) Query: 231 ALLDEMRAAGVE-PDGFTASTVIAACCRD--------GLVDEAVAFFEDLKARGHAPCVV 281 AL D + +G + PD T ++A RD L+++A+A E + H Sbjct: 76 ALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAA 135 Query: 282 TYNALLQVFGKAGNYTEA-----------LRVLGEMEQNGCQPD-AVTYNELAGTYARAG 329 T N L ++GK G Y EA +VLG+ PD A N LA G Sbjct: 136 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD-----HPDVAKQLNNLALLCQNQG 190 Query: 330 FFEEA----ARCLDTMASKGLLPN----AFTYNTVMTAYGNVGKVDEALALFDQM 376 +EE R L+ +K L P+ A T N + + Y GK +A L+ ++ Sbjct: 191 KYEEVEYYYQRALEIYQTK-LGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEI 244 >5OJF-A nrPDB Length = 314 Score = 35.4 bits (80), Expect = 0.097, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 73/175 (41%), Gaps = 35/175 (20%) Query: 231 ALLDEMRAAGVE-PDGFTASTVIAACCRD--------GLVDEAVAFFEDLKARGHAPCVV 281 AL D + +G + PD T ++A RD L+++A+A E + H Sbjct: 54 ALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAA 113 Query: 282 TYNALLQVFGKAGNYTEA-----------LRVLGEMEQNGCQPD-AVTYNELAGTYARAG 329 T N L ++GK G Y EA +VLG+ PD A + LA G Sbjct: 114 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKF-----HPDVAKQLSNLALLCQNQG 168 Query: 330 FFEEAA----RCLDTMASKGLLPN----AFTYNTVMTAYGNVGKVDEALALFDQM 376 EE R L+ A++ L P+ A T N + + Y GK +A L+ ++ Sbjct: 169 KAEEVEYYYRRALEIYATR-LGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEI 222 >3ZFW-A nrPDB Length = 263 Score = 35.4 bits (80), Expect = 0.11, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 73/175 (41%), Gaps = 35/175 (20%) Query: 231 ALLDEMRAAGVE-PDGFTASTVIAACCRD--------GLVDEAVAFFEDLKARGHAPCVV 281 AL D + +G + PD T ++A RD L+++A+A E + H Sbjct: 7 ALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAA 66 Query: 282 TYNALLQVFGKAGNYTEA-----------LRVLGEMEQNGCQPD-AVTYNELAGTYARAG 329 T N L ++GK G Y EA +VLG+ PD A + LA G Sbjct: 67 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKF-----HPDVAKQLSNLALLCQNQG 121 Query: 330 FFEEAA----RCLDTMASKGLLPN----AFTYNTVMTAYGNVGKVDEALALFDQM 376 EE R L+ A++ L P+ A T N + + Y GK +A L+ ++ Sbjct: 122 KAEEVEYYYRRALEIYATR-LGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEI 175 >6GAZ-Ae nrPDB Length = 390 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 31/61 (50%) Query: 246 FTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGE 305 +T T I C + G D+A+ ++ G P T+N L+ F K NY +AL V+ E Sbjct: 82 WTIHTWIRQCLKYGAQDKALYTLKNKVQYGIFPDNYTFNLLMDYFIKKENYKDALSVVFE 141 Query: 306 M 306 + Sbjct: 142 I 142 >3JD5-e nrPDB Length = 415 Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 30/62 (48%) Query: 245 GFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLG 304 +T T I C + G D+A+ + G P T+N L+ F K NY +AL V+ Sbjct: 106 NWTIHTWIRQCLKYGAQDKALYTLVNKVQYGIFPDNYTFNLLMDHFIKKENYKDALSVVF 165 Query: 305 EM 306 E+ Sbjct: 166 EI 167 >2YFT-A nrPDB Length = 571 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 19/37 (51%), Positives = 24/37 (64%), Gaps = 5/37 (13%) Query: 364 GKVDEALALFD----QMKKTGFVPNVNTYNLVLGMLG 396 GKV E L ++D Q KTG+V N N Y LV+GM+G Sbjct: 120 GKV-EDLEIWDSWPVQDAKTGYVSNWNGYQLVIGMMG 155 >3H4S-A nrPDB Length = 386 Score = 33.5 bits (75), Expect = 0.41, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 451 VELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSR 502 V+ + D YN I AYG+ GS F +Y ++ G TP T L N+L R Sbjct: 80 VQSAVDGYNVCIFAYGQTGS-GKTFTIYGHESNPGLTPRAT--KELFNILKR 128 >3DV0-B nrPDB Length = 325 Score = 32.7 bits (73), Expect = 0.70, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 12/103 (11%) Query: 595 DLVIFNSMLSIY------AKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESW 648 D VIF L +Y G Y+ D IKR G +I Y +++ K + Sbjct: 166 DPVIFLEHLKLYRSFRQEVPEGEYTIPIGKAD-IKREGKDITIIAYGAMVHESLKAAAEL 224 Query: 649 EAEKILNQLKCSQTMKPDVVSYNTVINGFCKQG---LVKEAQR 688 E E I ++ +T++P + T+I K G +V+EAQR Sbjct: 225 EKEGISAEVVDLRTVQP--LDIETIIGSVEKTGRAIVVQEAQR 265 >6E85-A nrPDB Length = 331 Score = 32.0 bits (71), Expect = 1.00, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 4/60 (6%) Query: 220 GRMGRSWPRIVA-LLDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAP 278 G G RIVA + MRA GVE G + C +G+ D VA + D +GH P Sbjct: 220 GLFGDEEIRIVAPAVAAMRAKGVEVTGPCPPDTVFMQCHEGMYDMVVAMYHD---QGHIP 276 >5YJE-A nrPDB Length = 380 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 5/68 (7%) Query: 19 PRKRGPLLPAAPPPPSPSSLPLDSLLLHLTAPAPA---PAPAPRRSH--QTPTPPHSFLS 73 PRK L+P + SP++L + + L+APA A P P+P+R+ Q + P ++ Sbjct: 4 PRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIE 63 Query: 74 PDAQVLVL 81 + +V V+ Sbjct: 64 VENEVTVV 71 >6HIX-BI nrPDB Length = 343 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%) Query: 212 YNVVLDVYGRMGRSWPRIVALLDEMRAAGVEPDGFT-ASTVIAACCRDGLVDEAVAFFED 270 YN V+ + +PR LL EMR G+EP+ + + ++ A D+A AFF + Sbjct: 147 YNAVMQA-AAFAKDFPRCEQLLAEMRGLGLEPNAQSYVNMMLGARLTGKPRDQAEAFFRE 205 Query: 271 LKARGHAPCVVTYNALLQVF 290 G V+ + Q++ Sbjct: 206 GIKTGAISAVMRLDTEFQMW 225 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 314 DAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGK-VDEALAL 372 D YN + A A F + L M GL PNA +Y +M GK D+A A Sbjct: 143 DHYIYNAVMQAAAFAKDFPRCEQLLAEMRGLGLEPNAQSYVNMMLGARLTGKPRDQAEAF 202 Query: 373 FDQMKKTGFVPNV 385 F + KTG + V Sbjct: 203 FREGIKTGAISAV 215 Score = 29.3 bits (64), Expect = 6.3, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 493 YNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSY-SLLLQCYAKGGNVAGIAAIENEV 551 YNA++ + D+ + ++++MR G +PN QSY +++L G A E Sbjct: 147 YNAVMQAAAFAKDFPRCEQLLAEMRGLGLEPNAQSYVNMMLGARLTGKPRDQAEAFFREG 206 Query: 552 YGSGAV 557 +GA+ Sbjct: 207 IKTGAI 212 >4UZY-A nrPDB Length = 651 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 418 PNRVTWNTMLAVCG-KRGMEDYVTRVL-EGMRSCGVELSRDTYNTLIAAYGRCGSRTNAF 475 P N +L C G D VL E + G LS D Y+ L AA GR S AF Sbjct: 312 PPETFANLLLLYCKPSHGFYDLAADVLAENPQYAGKLLSPDLYDYLQAAIGRYKSPEEAF 371 Query: 476 KMYNEMTS 483 + ++E+ + Sbjct: 372 RRFDELAT 379 >5CQS-A nrPDB Length = 435 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 6/90 (6%) Query: 294 GNYTEALRVLGEMEQNG-CQPDAVTYNELAGTYARA----GFFEEAARCLDTMASKGLLP 348 GNY +AL L E++++G + + Y E Y + E + + +K L Sbjct: 61 GNYEKALEHLSEIDKDGNVSEEVIDYVESHDLYKHGLALYRYDSEKQNVIYNIYAKHLSS 120 Query: 349 NAFTYNTVMTAYGNVGKVDEALALFDQMKK 378 N Y AY +GK+ EA+ + K+ Sbjct: 121 NQM-YTDAAVAYEMLGKLKEAMGAYQSAKR 149 >6HIW-DG nrPDB Length = 631 Score = 29.6 bits (65), Expect = 6.0, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%) Query: 221 RMGRSWPRIVALLDEMRAAGVEPDGFTASTVIAACCRDG--LVDEAVAFFEDLKARGHAP 278 R S P ++ L EM+ GV+ D T + ++ R VD+ F++L A G P Sbjct: 75 RACHSLPSMLLLYKEMKQRGVKVDVDTMNVLLTRAARHEHIQVDDVFLLFDELVALGARP 134 Query: 279 CVVTYNALLQVFGKAGNYTEALR 301 + L V + + E R Sbjct: 135 DLAAAETLHTVLSHSASMPEEWR 157 >2ZIV-A nrPDB Length = 311 Score = 29.3 bits (64), Expect = 6.4, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 568 VIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGL 627 ++AN C + E + +K + V ++ I +G KA V + Sbjct: 205 MVANLSCSLMAFTEFNYGAIKNKCQTVREVFARQLMQISGVSG--DKAAAVLEHYS---- 258 Query: 628 SPDLITYNSLMDMYAKCSESWEAEKILNQLK 658 T +SL+ Y KCS E EK+L+ +K Sbjct: 259 -----TVSSLLQAYDKCSSETEKEKLLSSVK 284 >4IFS-A nrPDB Length = 243 Score = 28.9 bits (63), Expect = 8.0, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 155 DAVCALLDETPLPPGSRLDVRAYTTVLHALSRAGRYE 191 DA+C + L P R D+R Y T LH + Y+ Sbjct: 10 DAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYK 46 >4ME2-A nrPDB Length = 257 Score = 28.9 bits (63), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 19/32 (59%) Query: 102 LLRADITSLLKALELSGHWEWALALLRWAGKE 133 LLRAD+ + + L+ GHW ALA L A E Sbjct: 80 LLRADLLAAMAELQRQGHWSLALAALHVARAE 111 >4P7A-A nrPDB Length = 348 Score = 28.9 bits (63), Expect = 9.7, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 14/77 (18%) Query: 320 ELAGTYA--RAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGN--------VGKVDEA 369 E+ G Y+ AG + +T+A LPNA T + + + +GN +G D+ Sbjct: 179 EVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKT 238 Query: 370 LALFDQMKKTGFVPNVN 386 LA K G++ N N Sbjct: 239 LAF----KMNGYISNAN 251 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4M57-A nrPDB 1292 0.0 6GAW-Ao nrPDB 306 3e-83 6GAZ-Ao nrPDB 214 2e-55 5G05-C nrPDB 120 3e-27 Sequences not found previously or not previously below threshold: 4LEU-A nrPDB 47 3e-05 5DIZ-A nrPDB 46 7e-05 5YJE-A nrPDB 36 0.061 4UZY-A nrPDB 35 0.083 6HIW-DG nrPDB 35 0.10 6F5D-J nrPDB 35 0.10 5G04-F nrPDB 34 0.22 6HIX-BI nrPDB 34 0.30 6HIW-DH nrPDB 34 0.34 6NU3-AV nrPDB 33 0.45 3JD5-e nrPDB 33 0.47 4FQM-A nrPDB 33 0.47 6GAZ-Ae nrPDB 33 0.57 4XGL-A nrPDB 32 1.2 5A5T-C nrPDB 32 1.4 4MMI-A nrPDB 31 1.6 4ME2-A nrPDB 31 2.2 2RFT-A nrPDB 31 2.3 6E85-A nrPDB 30 2.8 4M44-A nrPDB 30 3.8 3GSZ-A nrPDB 30 4.0 3H4S-A nrPDB 30 5.1 1BF2-A nrPDB 29 6.0 3KF9-A nrPDB 29 6.4 4IFS-A nrPDB 29 6.8 4XMN-D nrPDB 29 9.0 >4M57-A nrPDB Length = 726 Score = 1292 bits (3344), Expect = 0.0, Method: Composition-based stats. Identities = 722/726 (99%), Positives = 722/726 (99%) Query: 61 SHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHW 120 SHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHW Sbjct: 1 SHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHW 60 Query: 121 EWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTV 180 EWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTV Sbjct: 61 EWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTV 120 Query: 181 LHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAG 240 LHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAG Sbjct: 121 LHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAG 180 Query: 241 VEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEAL 300 VEPDGFTASTVIAAC RDGLVDEAVAFFEDLKARGHAP VVTYNALLQVFGKAGNYTEAL Sbjct: 181 VEPDGFTASTVIAACSRDGLVDEAVAFFEDLKARGHAPSVVTYNALLQVFGKAGNYTEAL 240 Query: 301 RVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAY 360 RVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAY Sbjct: 241 RVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAY 300 Query: 361 GNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNR 420 GNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNR Sbjct: 301 GNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNR 360 Query: 421 VTWNTMLAVCGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNE 480 VTWNTMLAV GKRGMEDYVTRVLEGMRS GVELSRDTYNTLIAAYGRCGSRTNAFKMYNE Sbjct: 361 VTWNTMLAVSGKRGMEDYVTRVLEGMRSSGVELSRDTYNTLIAAYGRCGSRTNAFKMYNE 420 Query: 481 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN 540 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN Sbjct: 421 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN 480 Query: 541 VAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFN 600 VAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFN Sbjct: 481 VAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFN 540 Query: 601 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCS 660 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCS Sbjct: 541 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCS 600 Query: 661 QTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSE 720 QTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSE Sbjct: 601 QTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSE 660 Query: 721 AREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIE 780 AREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIE Sbjct: 661 AREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIE 720 Query: 781 DAQFGR 786 DAQFGR Sbjct: 721 DAQFGR 726 >6GAW-Ao nrPDB Length = 692 Score = 306 bits (783), Expect = 3e-83, Method: Composition-based stats. Identities = 57/266 (21%), Positives = 113/266 (42%), Gaps = 45/266 (16%) Query: 476 KMYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCY 535 M++++ AG T + T N+LL++L G+ + + + R + + E + + + Sbjct: 171 DMFDQLLQAGTTVSLETTNSLLDLLCYYGNQEPSANYNFQQREQSEELEEATEADNEKSK 230 Query: 536 AKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPD 595 K G+ G+ +W R + E F + + + Sbjct: 231 TKAGHHLGV---------------TW-------------RTKNNAERIFALMPEKNAHS- 261 Query: 596 LVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYA-----KCSESWEA 650 + +M+ K+ ++A ++ + + L D+ T+NSL++ A K E W Sbjct: 262 ---YCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWN- 317 Query: 651 EKILNQLK--CSQTMKPDVVSYNTVIN---GFCKQGLVKEAQRVLSEMVADGMAPCAVTY 705 IL+ LK +Q +KP++ ++NT++ F G + Q L EM A G+ P TY Sbjct: 318 -NILDLLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKLPALQ-TLREMKAIGIEPSLATY 375 Query: 706 HTLVGGYSSLEMFSEAREVIGYMVQH 731 H ++ + E S+ +I Y + + Sbjct: 376 HYVIQLFYQHESPSKGSSLIIYDIMN 401 Score = 281 bits (718), Expect = 9e-76, Method: Composition-based stats. Identities = 100/539 (18%), Positives = 194/539 (35%), Gaps = 66/539 (12%) Query: 261 VDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGEMEQNGCQPDAVTYNE 320 V +V F+ L G + T N+LL + GN + + + + + T + Sbjct: 166 VKASVDMFDQLLQAGTTVSLETTNSLLDLLCYYGNQEPSANYNFQQREQSEELEEATEAD 225 Query: 321 LAGTYARAGFF--------EEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALAL 372 + +AG A R M K NA +Y T++ +AL L Sbjct: 226 NEKSKTKAGHHLGVTWRTKNNAERIFALMPEK----NAHSYCTMIRGMVKHQAPTQALNL 281 Query: 373 FDQMKKTGFVPNVNTYNLVLG----MLGKK--SRFTVMLEMLGEMSRSGCTPNRVTWNTM 426 + + +V T+N ++ ++ +K ++ +L++L +M PN T+NT+ Sbjct: 282 YTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTI 341 Query: 427 LAVCGKRGM---EDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRC-----GSRTNAFKMY 478 L C +R + + L M++ G+E S TY+ +I + + GS + + Sbjct: 342 LK-CLRRFYAFGKLPALQTLREMKAIGIEPSLATYHYVIQLFYQHESPSKGSSLIIYDIM 400 Query: 479 NEMTSAGFTP-----------CITTYNALLNV-LSRQGDWSTAQSIVSKMRTKGFKPN-E 525 NE+ F+P + ++L ++ L+ Q K+ + N Sbjct: 401 NEVMGKRFSPRDPDDDMFFQSAMRVCSSLRDLELAYQVHGLLNTGDNWKLIGSDHRRNFY 460 Query: 526 QSYSLLLQCYAKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQ 585 S L C+ + + + FP + L+ A RLD + ++ Sbjct: 461 YSKFFNLLCFME---QIDVTLKWYKDLIPSVFFPHSQTMIDLLQALDVANRLDMVPQIWK 517 Query: 586 EVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCS 645 + K G+ + +L + A++ + F + + D+ + D Sbjct: 518 DSKEYGHTFRNELKEEILMLMARDQHPPELQVAF-----ADCAADIKSTYESQDARQTAP 572 Query: 646 ESWEAEKILNQLKCSQTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTY 705 E W A S N V F + G +EA ++L P A Sbjct: 573 E-WPAS-----------------SLNYVAVLFLRAGRTQEAWKMLGLFRKHNKIPRAELL 614 Query: 706 HTLVGGYSSLEMFSEAREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVS 764 + + + ++A E++ L E RRV+ + + EA G L+ ++ Sbjct: 615 NEFLDSAKASSSPAQAIELVKLASAFSLPVCEGLTRRVMAEFTLTQEQREALGELTALT 673 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 70/370 (18%), Positives = 122/370 (32%), Gaps = 57/370 (15%) Query: 171 RLDVRAYTTVLHALSRA------GRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGR 224 R DV + +++ A + ++ L+L ++ Q V P L T+N +L R Sbjct: 291 RADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTILKCLRRF-Y 349 Query: 225 SWPRIVAL--LDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVT 282 ++ ++ AL L EM+A G+EP T VI F ++ ++ Sbjct: 350 AFGKLPALQTLREMKAIGIEPSLATYHYVI-------------QLFYQHESPSKGSSLII 396 Query: 283 YNALLQVFGK-AGNYTEALRVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTM 341 Y+ + +V GK + + C + +L Y G + Sbjct: 397 YDIMNEVMGKRFSPRDPDDDMFFQSAMRVC----SSLRDLELAYQVHGLLNTGDNW--KL 450 Query: 342 ASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRF 401 N F Y+ + ++D L + + + F P+ T +L L +R Sbjct: 451 IGSDHRRN-FYYSKFFNLLCFMEQIDVTLKWYKDLIPSVFFPHSQTMIDLLQALDVANRL 509 Query: 402 TVML-------------------EMLGEMSRSGCTPNRVTWNTMLAVCGKRGMEDYVTRV 442 ++ E+L M+R P A K E Sbjct: 510 DMVPQIWKDSKEYGHTFRNELKEEILMLMARDQHPPELQVAFADCAADIKSTYES----- 564 Query: 443 LEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSR 502 + R E + N + + R G A+KM P N L+ S Sbjct: 565 -QDARQTAPEWPASSLNYVAVLFLRAGRTQEAWKMLGLFRKHNKIPRAELLNEFLD--SA 621 Query: 503 QGDWSTAQSI 512 + S AQ+I Sbjct: 622 KASSSPAQAI 631 >6GAZ-Ao nrPDB Length = 692 Score = 214 bits (544), Expect = 2e-55, Method: Composition-based stats. Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 17/167 (10%) Query: 575 RRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITY 634 R + E F + + + + +M+ K+ ++A ++ + + L D+ T+ Sbjct: 242 RTKNNAERIFALMPEKNAHS----YCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTF 297 Query: 635 NSLMDMYA-----KCSESWEAEKILNQLK--CSQTMKPDVVSYNTVIN---GFCKQGLVK 684 NSL++ A K E W IL+ LK +Q +KP++ ++NT++ F G + Sbjct: 298 NSLIEATALVVNEKFEEKWN--NILDLLKQMVTQNVKPNLQTFNTILKCLRRFYAFGKLP 355 Query: 685 EAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSEAREVIGYMVQH 731 Q L EM A G+ P TYH ++ + E S+ +I Y + + Sbjct: 356 ALQ-TLREMKAIGIEPSLATYHYVIQLFYQHESPSKGSSLIIYDIMN 401 Score = 185 bits (469), Expect = 7e-47, Method: Composition-based stats. Identities = 86/460 (18%), Positives = 167/460 (36%), Gaps = 58/460 (12%) Query: 332 EEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLV 391 A R M K NA +Y T++ +AL L+ + +V T+N + Sbjct: 245 NNAERIFALMPEK----NAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSL 300 Query: 392 LG----MLGKK--SRFTVMLEMLGEMSRSGCTPNRVTWNTMLAVCGKRGM---EDYVTRV 442 + ++ +K ++ +L++L +M PN T+NT+L C +R + + Sbjct: 301 IEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTILK-CLRRFYAFGKLPALQT 359 Query: 443 LEGMRSCGVELSRDTYNTLIAAYGRC-----GSRTNAFKMYNEMTSAGFTP--------- 488 L M++ G+E S TY+ +I + + GS + + NE+ F+P Sbjct: 360 LREMKAIGIEPSLATYHYVIQLFYQHESPSKGSSLIIYDIMNEVMGKRFSPRDPDDDMFF 419 Query: 489 --CITTYNALLNV-LSRQGDWSTAQSIVSKMRTKGFKPN-EQSYSLLLQCYAKGGNVAGI 544 + ++L ++ L+ Q K+ + N S L C+ + + Sbjct: 420 QSAMRVCSSLRDLELAYQVHGLLNTGDNWKLIGSDHRRNFYYSKFFNLLCFME---QIDV 476 Query: 545 AAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLS 604 + FP + L+ A RLD + +++ K G+ + +L Sbjct: 477 TLKWYKDLIPSVFFPHSQTMIDLLQALDVANRLDMVPQIWKDSKEYGHTFRNELKEEILM 536 Query: 605 IYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMK 664 + A++ + F + + D+ + D E W A Sbjct: 537 LMARDQHPPELQVAF-----ADCAADIKSTYESQDARQTAPE-WPAS------------- 577 Query: 665 PDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSEAREV 724 S N V F + G +EA ++L P A + + + ++A E+ Sbjct: 578 ----SLNYVAVLFLRAGRTQEAWKMLGLFRKHNKIPRAELLNEFLDSAKASSSPAQAIEL 633 Query: 725 IGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVS 764 + L E RRV+ + + EA G L+ ++ Sbjct: 634 VKLASAFSLPVCEGLTRRVMAEFTLTQEQREALGELTALT 673 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 70/370 (18%), Positives = 122/370 (32%), Gaps = 57/370 (15%) Query: 171 RLDVRAYTTVLHALSRA------GRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGR 224 R DV + +++ A + ++ L+L ++ Q V P L T+N +L R Sbjct: 291 RADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTILKCLRRF-Y 349 Query: 225 SWPRIVAL--LDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVT 282 ++ ++ AL L EM+A G+EP T VI F ++ ++ Sbjct: 350 AFGKLPALQTLREMKAIGIEPSLATYHYVI-------------QLFYQHESPSKGSSLII 396 Query: 283 YNALLQVFGK-AGNYTEALRVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTM 341 Y+ + +V GK + + C + +L Y G + Sbjct: 397 YDIMNEVMGKRFSPRDPDDDMFFQSAMRVC----SSLRDLELAYQVHGLLNTGDNW--KL 450 Query: 342 ASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRF 401 N F Y+ + ++D L + + + F P+ T +L L +R Sbjct: 451 IGSDHRRN-FYYSKFFNLLCFMEQIDVTLKWYKDLIPSVFFPHSQTMIDLLQALDVANRL 509 Query: 402 TVML-------------------EMLGEMSRSGCTPNRVTWNTMLAVCGKRGMEDYVTRV 442 ++ E+L M+R P A K E Sbjct: 510 DMVPQIWKDSKEYGHTFRNELKEEILMLMARDQHPPELQVAFADCAADIKSTYES----- 564 Query: 443 LEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSR 502 + R E + N + + R G A+KM P N L+ S Sbjct: 565 -QDARQTAPEWPASSLNYVAVLFLRAGRTQEAWKMLGLFRKHNKIPRAELLNEFLD--SA 621 Query: 503 QGDWSTAQSI 512 + S AQ+I Sbjct: 622 KASSSPAQAI 631 >5G05-C nrPDB Length = 597 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 321 LAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTG 380 LA Y EEA + + G +++ + + AY N+ +D+AL++F++++K Sbjct: 234 LAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD 293 Query: 381 --FVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSR 413 + N++T++ +L + KS + + L E+ + Sbjct: 294 PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328 >4LEU-A nrPDB Length = 257 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 4/111 (3%) Query: 286 LLQVFGKAGNYTEALRV--LGE--MEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTM 341 +L V G+ E + E +Q QPD Y +L + A++ +EA + M Sbjct: 110 MLAVIGELERQEETALAIKMFEVIQKQEWYQPDVFMYKDLIVSLAKSKRMDEAMALWEKM 169 Query: 342 ASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVL 392 + L P++ TY V+ + G +A+ +++ M K+ P + ++L Sbjct: 170 KKENLFPDSQTYTEVIRGFLRDGCPADAMNVYEDMLKSPDPPEELPFRVLL 220 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 40/81 (49%) Query: 559 PSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEV 618 P + + L+++ K +R+D ++++K PD + ++ + ++G + A V Sbjct: 141 PDVFMYKDLIVSLAKSKRMDEAMALWEKMKKENLFPDSQTYTEVIRGFLRDGCPADAMNV 200 Query: 619 FDSIKRSGLSPDLITYNSLMD 639 ++ + +S P+ + + L+ Sbjct: 201 YEDMLKSPDPPEELPFRVLLK 221 Score = 42.4 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 2/102 (1%) Query: 615 ATEVFDSI-KRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTV 673 A ++F+ I K+ PD+ Y L+ AK EA + ++K + + PD +Y V Sbjct: 126 AIKMFEVIQKQEWYQPDVFMYKDLIVSLAKSKRMDEAMALWEKMK-KENLFPDSQTYTEV 184 Query: 674 INGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSL 715 I GF + G +A V +M+ P + + L+ G Sbjct: 185 IRGFLRDGCPADAMNVYEDMLKSPDPPEELPFRVLLKGLLPH 226 Score = 36.6 bits (83), Expect = 0.048, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 369 ALALFDQMKKTG-FVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNRVTWNTML 427 A+ +F+ ++K + P+V Y ++ L K R + + +M + P+ T+ ++ Sbjct: 126 AIKMFEVIQKQEWYQPDVFMYKDLIVSLAKSKRMDEAMALWEKMKKENLFPDSQTYTEVI 185 Query: 428 AVCGKRGMEDYVTRVLEGM 446 + G V E M Sbjct: 186 RGFLRDGCPADAMNVYEDM 204 Score = 34.7 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 39/77 (50%) Query: 242 EPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALR 301 +PD F +I + + +DEA+A +E +K P TY +++ F + G +A+ Sbjct: 140 QPDVFMYKDLIVSLAKSKRMDEAMALWEKMKKENLFPDSQTYTEVIRGFLRDGCPADAMN 199 Query: 302 VLGEMEQNGCQPDAVTY 318 V +M ++ P+ + + Sbjct: 200 VYEDMLKSPDPPEELPF 216 Score = 34.3 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 11/122 (9%) Query: 171 RLDVRAYTTVLHALSRAGRYERALELFAELRRQG-VAPTLVTYN---VVLDVYGRMGRSW 226 +LD+ A V+ L R A+++F +++Q P + Y V L RM + Sbjct: 107 KLDMLA---VIGELERQEETALAIKMFEVIQKQEWYQPDVFMYKDLIVSLAKSKRMDEA- 162 Query: 227 PRIVALLDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNAL 286 +AL ++M+ + PD T + VI RDG +A+ +ED+ P + + L Sbjct: 163 ---MALWEKMKKENLFPDSQTYTEVIRGFLRDGCPADAMNVYEDMLKSPDPPEELPFRVL 219 Query: 287 LQ 288 L+ Sbjct: 220 LK 221 >5DIZ-A nrPDB Length = 531 Score = 45.9 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 71/193 (36%), Gaps = 13/193 (6%) Query: 362 NVGKVDEALALFDQ-MKKTGFVPNVNTYNLVLGMLGKKS---RFTVML-----EMLGEMS 412 + ALAL+D + + + + +L + + E+ M Sbjct: 45 KSKDLSAALALYDAAITSSEVRLSQQHFQTLLYLCSASITDISLQYLAIDRGFEIFDRMV 104 Query: 413 RSGCTPNRVTWNTMLAVCGKRGMEDYVTRVLEGMRSCG--VELSRDTYNTLIAAYGRCGS 470 SG +PN + ++ + +G DY +V++ S G TY + + Sbjct: 105 SSGISPNEASVTSVARLAAAKGNGDYAFKVVKEFVSVGGVSIPRLRTYAPALLCFCEKLE 164 Query: 471 RTNAFKMYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSL 530 +++ M +AG +ALL V + G + + K+R +E++ + Sbjct: 165 AEKGYEVEEHMEAAGIALEEAEISALLKVSAATGRENKVYRYLHKLREYVGCVSEETLKI 224 Query: 531 LLQ--CYAKGGNV 541 + + C K G V Sbjct: 225 IEEWFCGEKAGEV 237 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 61/160 (38%), Gaps = 11/160 (6%) Query: 601 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMD-MYAKCSESWEAEKILNQLKC 659 S+ I + + E+FD + SG+SP+ + S+ AK + + + + + Sbjct: 82 SITDISLQYLAIDRGFEIFDRMVSSGISPNEASVTSVARLAAAKGNGDYAFKVVKEFVSV 141 Query: 660 SQTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFS 719 P + +Y + FC++ ++ V M A G+A L+ + Sbjct: 142 GGVSIPRLRTYAPALLCFCEKLEAEKGYEVEEHMEAAGIALEEAEISALLKV-----SAA 196 Query: 720 EAREVIGYMVQHGLKPM-----ELTYRRVVESYCRAKRFE 754 RE Y H L+ E T + + E +C K E Sbjct: 197 TGRENKVYRYLHKLREYVGCVSEETLKIIEEWFCGEKAGE 236 >5YJE-A nrPDB Length = 380 Score = 36.2 bits (82), Expect = 0.061, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 19 PRKRGPLLPAAPPPPSPSSLPLDSLLLHLTAPAPA---PAPAPRRSH--QTPTPPHSFLS 73 PRK L+P + SP++L + + L+APA A P P+P+R+ Q + P ++ Sbjct: 4 PRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIE 63 Query: 74 PDAQVLVLA 82 + +V V+ Sbjct: 64 VENEVTVVG 72 >4UZY-A nrPDB Length = 651 Score = 35.5 bits (80), Expect = 0.083, Method: Composition-based stats. Identities = 55/252 (21%), Positives = 88/252 (34%), Gaps = 22/252 (8%) Query: 237 RAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKAR-GHAPCVVTYNALLQVFGKAGN 295 + A +PD + I ++G + A F D G+ P ++ YN L Sbjct: 141 KCAPEDPDTMVNTGCIMF--KEGKFEAARQKFNDAVQALGYQPELL-YNIAL---CYYKT 194 Query: 296 YT--EALRVLGEMEQNG--CQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAF 351 AL+ L E+ + P+ + G R+ + + + L A Sbjct: 195 KQFGPALKHLAEIIEKAVREHPELSVGSNTDGMEVRSVGNSQTLKETA-LIEAFNLKAAI 253 Query: 352 TYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEM 411 Y NV EAL + P V +N L + S T + L + Sbjct: 254 EYT-----MKNVEAAKEALTDMPPRAEEELDP-VTLHNSAL--INMDSDPTGGFKKLNFL 305 Query: 412 SRSGCTPNRVTWNTMLAVC--GKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCG 469 +S P N +L C + + E + G LS D Y+ L AA GR Sbjct: 306 LQSPPFPPETFANLLLLYCKPSHGFYDLAADVLAENPQYAGKLLSPDLYDYLQAAIGRYK 365 Query: 470 SRTNAFKMYNEM 481 S AF+ ++E+ Sbjct: 366 SPEEAFRRFDEL 377 >6HIW-DG nrPDB Length = 631 Score = 35.5 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 40/95 (42%), Gaps = 5/95 (5%) Query: 574 CRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNG--MYSKATEVFDSIKRSGLSPDL 631 C L M ++E+K RG D+ N +L+ A++ +FD + G PDL Sbjct: 77 CHSLPSMLLLYKEMKQRGVKVDVDTMNVLLTRAARHEHIQVDDVFLLFDELVALGARPDL 136 Query: 632 I---TYNSLMDMYAKCSESWEAEKILNQLKCSQTM 663 T ++++ A E W + L ++ + Sbjct: 137 AAAETLHTVLSHSASMPEEWREARRLQLVELYNNL 171 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 7/83 (8%) Query: 423 WNTMLAVCGKRGMEDYVTRVL-EGMRSCGVELSRDTYNTLI--AAYGRCGSRTNAFKMYN 479 +N L C +L + M+ GV++ DT N L+ AA + F +++ Sbjct: 70 YNGALRAC----HSLPSMLLLYKEMKQRGVKVDVDTMNVLLTRAARHEHIQVDDVFLLFD 125 Query: 480 EMTSAGFTPCITTYNALLNVLSR 502 E+ + G P + L VLS Sbjct: 126 ELVALGARPDLAAAETLHTVLSH 148 Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%) Query: 221 RMGRSWPRIVALLDEMRAAGVEPDGFTASTVIAACCRDG--LVDEAVAFFEDLKARGHAP 278 R S P ++ L EM+ GV+ D T + ++ R VD+ F++L A G P Sbjct: 75 RACHSLPSMLLLYKEMKQRGVKVDVDTMNVLLTRAARHEHIQVDDVFLLFDELVALGARP 134 Query: 279 CVVTYNALLQVFGKAGNYTEALR 301 + L V + + E R Sbjct: 135 DLAAAETLHTVLSHSASMPEEWR 157 >6F5D-J nrPDB Length = 170 Score = 35.5 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 12/80 (15%) Query: 367 DEALALFDQMKKTGFVPNVNTYNLVLGM-----------LGKKSRFTVMLEMLGEMSRSG 415 DEA + M + P++ TYN L + +S+F M+++L EM Sbjct: 34 DEAGEVLVNMNVSNCPPDIATYNATLQCIYQSPSKQSTPVDNESKFCAMMDLLEEMQHRN 93 Query: 416 -CTPNRVTWNTMLAVCGKRG 434 PN +W ++ C K G Sbjct: 94 RLKPNEESWTWVMKECVKSG 113 >5G04-F nrPDB Length = 824 Score = 34.3 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 36/86 (41%), Gaps = 3/86 (3%) Query: 332 EEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKK--TGFVPNVNTYN 389 +EA L + S + + AY + + +A +F ++++ V + Y+ Sbjct: 482 KEAINILSHLPSHHYN-TGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 Query: 390 LVLGMLGKKSRFTVMLEMLGEMSRSG 415 L L K +V+ + L +M ++ Sbjct: 541 TTLWHLQKDVALSVLSKDLTDMDKNS 566 >6HIX-BI nrPDB Length = 343 Score = 33.9 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 7/97 (7%) Query: 314 DAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKV-DEALAL 372 D YN + A A F + L M GL PNA +Y +M GK D+A A Sbjct: 143 DHYIYNAVMQAAAFAKDFPRCEQLLAEMRGLGLEPNAQSYVNMMLGARLTGKPRDQAEAF 202 Query: 373 FDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLG 409 F + KTG + + V+ + + + LE LG Sbjct: 203 FREGIKTGAI------SAVMRLDTEFQMWMNQLERLG 233 Score = 30.1 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 46/126 (36%), Gaps = 6/126 (4%) Query: 212 YNVVLDVYGRMGRSWPRIVALLDEMRAAGVEPDGFTASTVIAACCRDGLV-DEAVAFFED 270 YN V+ + +PR LL EMR G+EP+ + ++ G D+A AFF + Sbjct: 147 YNAVMQA-AAFAKDFPRCEQLLAEMRGLGLEPNAQSYVNMMLGARLTGKPRDQAEAFFRE 205 Query: 271 LKARGHAPCVVTYNALLQV----FGKAGNYTEALRVLGEMEQNGCQPDAVTYNELAGTYA 326 G V+ + Q+ + G++ + L E+ + Sbjct: 206 GIKTGAISAVMRLDTEFQMWMNQLERLGSFKAKVGYLSVNEEGASPMPRDMWALWGWHRT 265 Query: 327 RAGFFE 332 A F Sbjct: 266 EAKFIS 271 >6HIW-DH nrPDB Length = 581 Score = 33.5 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Query: 425 TMLAV-CGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTS 483 T LAV CG R + L + ++ TL+ + +Y+ M S Sbjct: 177 TSLAVDCGGRTQPSHFVPYLPQGTAAASHITNALMRTLLTCGYTHVAA-IPDSVYDRMGS 235 Query: 484 AGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFK 522 G +P I+TY ++ LS QG+ A+SI+S +R+ + Sbjct: 236 MGISPTISTYELVMLALSLQGNMVEAESILSFLRSHHSE 274 >6NU3-AV nrPDB Length = 414 Score = 33.1 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 72/241 (29%), Gaps = 28/241 (11%) Query: 320 ELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKT 379 + + E + L N +T +T + D+AL + Sbjct: 77 DNISSREEIDHAEYYLYKFRHSPNCWYLRN-WTIHTWIRQCLKYDAQDKALYTLVNKVQY 135 Query: 380 GFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGC--TPNRVTWNT-MLAVCG----- 431 G P+ T+NL++ KK + L ++ E+ P+ + +L C Sbjct: 136 GIFPDNFTFNLLMDSFIKKENYKDALSVVFEVMMQEAFEVPSTQLLSLYVLFHCLAKKTD 195 Query: 432 ------KRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKM-------- 477 + + L+ S G Y L + G R M Sbjct: 196 FSWEEERNFGASLLLPGLKQKNSVGFSSQLYGYALLGKVELQQGLRAVYHNMPLIWKPGY 255 Query: 478 YNEMTS-----AGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLL 532 + A I L+VL T+ S+ +++ + N+ S L+ Sbjct: 256 LDRALQVMEKVAASPEDIKLCREALDVLGAVLKALTSADGASEEQSQNDEDNQGSEKLVE 315 Query: 533 Q 533 Q Sbjct: 316 Q 316 Score = 29.3 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 11/131 (8%) Query: 246 FTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGE 305 +T T I C + D+A+ + G P T+N L+ F K NY +AL V+ E Sbjct: 107 WTIHTWIRQCLKYDAQDKALYTLVNKVQYGIFPDNFTFNLLMDSFIKKENYKDALSVVFE 166 Query: 306 MEQNGCQPDAVTYNELAGTYA-------RAGFFEEAARCL--DTMASKGLLPNAFTYNTV 356 + + V +L Y + F E R + N+ +++ Sbjct: 167 VMMQ--EAFEVPSTQLLSLYVLFHCLAKKTDFSWEEERNFGASLLLPGLKQKNSVGFSSQ 224 Query: 357 MTAYGNVGKVD 367 + Y +GKV+ Sbjct: 225 LYGYALLGKVE 235 >3JD5-e nrPDB Length = 415 Score = 33.1 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 35/97 (36%), Gaps = 1/97 (1%) Query: 318 YNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMK 377 + + + E + L N +T +T + G D+AL Sbjct: 75 FVDNISSREEIDHAEYYLYKFRHSPNCWYLRN-WTIHTWIRQCLKYGAQDKALYTLVNKV 133 Query: 378 KTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRS 414 + G P+ T+NL++ KK + L ++ E+ Sbjct: 134 QYGIFPDNYTFNLLMDHFIKKENYKDALSVVFEIMMQ 170 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 30/64 (46%) Query: 246 FTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGE 305 +T T I C + G D+A+ + G P T+N L+ F K NY +AL V+ E Sbjct: 107 WTIHTWIRQCLKYGAQDKALYTLVNKVQYGIFPDNYTFNLLMDHFIKKENYKDALSVVFE 166 Query: 306 MEQN 309 + Sbjct: 167 IMMQ 170 Score = 28.9 bits (63), Expect = 8.2, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 24/54 (44%) Query: 601 SMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKIL 654 + + K G KA + + G+ PD T+N LMD + K +A ++ Sbjct: 111 TWIRQCLKYGAQDKALYTLVNKVQYGIFPDNYTFNLLMDHFIKKENYKDALSVV 164 >4FQM-A nrPDB Length = 347 Score = 33.1 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 10/75 (13%) Query: 703 VTYHTL--VGGYSSLE----MFSEAREVIGYMVQHGLKPMELTYRRVV----ESYCRAKR 752 VT H + +GG+ + + R V+ YMVQ K +TY+R + + +C + R Sbjct: 220 VTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGR 279 Query: 753 FEEARGFLSEVSETD 767 + +G L + E D Sbjct: 280 SKVIKGSLPLIGEAD 294 >6GAZ-Ae nrPDB Length = 390 Score = 32.8 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 31/64 (48%) Query: 246 FTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGE 305 +T T I C + G D+A+ ++ G P T+N L+ F K NY +AL V+ E Sbjct: 82 WTIHTWIRQCLKYGAQDKALYTLKNKVQYGIFPDNYTFNLLMDYFIKKENYKDALSVVFE 141 Query: 306 MEQN 309 + Sbjct: 142 IMMQ 145 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 35/97 (36%), Gaps = 1/97 (1%) Query: 318 YNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMK 377 + + + E + L + +T +T + G D+AL Sbjct: 50 FVDNIASREDIDHAEYYLYKFRHSPNCWYLRD-WTIHTWIRQCLKYGAQDKALYTLKNKV 108 Query: 378 KTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRS 414 + G P+ T+NL++ KK + L ++ E+ Sbjct: 109 QYGIFPDNYTFNLLMDYFIKKENYKDALSVVFEIMMQ 145 Score = 29.7 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 51/292 (17%), Positives = 97/292 (33%), Gaps = 44/292 (15%) Query: 422 TWNTMLAVCGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAY-----GRCGSRTNAFK 476 T +T + C K G +D L+ G+ T+N L+ + + Sbjct: 83 TIHTWIRQCLKYGAQDKALYTLKNKVQYGIFPDNYTFNLLMDYFIKKENYKDALSVVFEI 142 Query: 477 MYNEMTSAGFTPCITTYNALLNVLSRQGD--WSTAQSIVSKMRTKGFKPNEQSYSLLLQC 534 M E T ++ Y L + L+ + D W ++ + + G K Q S+ L Sbjct: 143 MMQEAFEVPSTQLLSLY-VLYHCLAEKTDLSWEEERNFGASLLLPGLK---QKNSVGLSS 198 Query: 535 YAKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNP 594 G + G ++ + P L + R L ME G Sbjct: 199 QLYGYALLGKVELQQGLRAVYCNMP------LLWQPGYLHRALQVMEKV-ASSPEDG--- 248 Query: 595 DLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKIL 654 + +A +V D + ++ +P T + + ES +E+++ Sbjct: 249 ---------------QLCGEALDVLDRVLKAVTAPAQGTSE---EQPQEGEESQRSEELV 290 Query: 655 NQLKCSQTMKPD----VVSYNTVINGFCKQGLVK-EAQRVLSEMVADGMAPC 701 QL +T + + + + + G V+ E+ LS +A P Sbjct: 291 EQLDVEETEQSKLPQYLERFEALRSKLQALGKVESESLLTLSTQLAKAQLPT 342 >4XGL-A nrPDB Length = 379 Score = 32.0 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 39/123 (31%), Gaps = 19/123 (15%) Query: 439 VTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITT------ 492 +LE ++ + S+ YN I A+ +Y E+ P + T Sbjct: 25 ALLLLEDIKKV-ITPSKKNYNDCIQGALLHQDVNTAWNLYQELLGHDIVPMLETLKAFFD 83 Query: 493 ----------YNALLNVLSRQGDWS--TAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGN 540 N LL++LS + +S ++T + + K G Sbjct: 84 FGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAHSIKTWFESVPGKQWKGQFTTVRKSGQ 143 Query: 541 VAG 543 +G Sbjct: 144 CSG 146 Score = 30.1 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 18/46 (39%) Query: 342 ASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNT 387 K + P+ YN + V+ A L+ ++ VP + T Sbjct: 32 IKKVITPSKKNYNDCIQGALLHQDVNTAWNLYQELLGHDIVPMLET 77 >5A5T-C nrPDB Length = 843 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 47/131 (35%), Gaps = 18/131 (13%) Query: 260 LVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGN----YTEALRVLGEMEQNGCQPDA 315 LV E F HA + N +LQ GK G E L++L ++ + Sbjct: 240 LVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIASENNLGEG 299 Query: 316 VT-------------YNELAGTYARAGFFEEAARCLDTMASKGLL-PNAFTYNTVMTAYG 361 V YN TY + +++ C++ + PN F ++ Sbjct: 300 VIVKIKFNIIASLYDYNPNLATYMKPEMWQKCLDCINELMDILFANPNIFVGENILEESE 359 Query: 362 NVGKVDEALAL 372 N+ VD+ L + Sbjct: 360 NLQNVDQPLRV 370 >4MMI-A nrPDB Length = 643 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 44/115 (38%), Gaps = 10/115 (8%) Query: 560 SWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVF 619 + ++L+ F + +G F +K R + PD +F +Y+ + K + Sbjct: 387 TVMVLKASPPGEFHAQPDNGTFELF--IKGRNFTPDAGVF-----VYSGDEAIMKLRNWY 439 Query: 620 DSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTVI 674 +++ + L N M + WE L+ L + P++ +V+ Sbjct: 440 ---RQTRIHSTLTLDNQNMVITKARQNKWETGNNLDVLTYTNPSYPNLDHQRSVL 491 >4ME2-A nrPDB Length = 257 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 15/32 (46%), Positives = 19/32 (59%) Query: 102 LLRADITSLLKALELSGHWEWALALLRWAGKE 133 LLRAD+ + + L+ GHW ALA L A E Sbjct: 80 LLRADLLAAMAELQRQGHWSLALAALHVARAE 111 >2RFT-A nrPDB Length = 344 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 10/75 (13%) Query: 703 VTYHTL--VGGYSSLE----MFSEAREVIGYMVQHGLKPMELTYRRVV----ESYCRAKR 752 VT H + +GG+ + + R V+ YMVQ K + Y+R V + +C + R Sbjct: 217 VTTHYVSQIGGFPNQAEDEGLPQSGRIVVDYMVQKPGKTGTIAYQRGVLLPQKVWCASGR 276 Query: 753 FEEARGFLSEVSETD 767 + +G L + E D Sbjct: 277 SKVIKGSLPLIGEAD 291 >6E85-A nrPDB Length = 331 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 12/75 (16%) Query: 220 GRMGRSWPRIVA-LLDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAP 278 G G RIVA + MRA GVE G + C +G+ D VA + D +GH P Sbjct: 220 GLFGDEEIRIVAPAVAAMRAKGVEVTGPCPPDTVFMQCHEGMYDMVVAMYHD---QGHIP 276 Query: 279 CVVTYNALLQVFGKA 293 L++ G Sbjct: 277 --------LKLLGFY 283 >4M44-A nrPDB Length = 346 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 10/75 (13%) Query: 703 VTYHTL--VGGYSSLE----MFSEAREVIGYMVQHGLKPMELTYRRVV----ESYCRAKR 752 VT H + +GG+ + R V+ YMVQ K + Y+R + + +C + R Sbjct: 219 VTTHYVSQIGGFPDQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGILLPQKVWCASGR 278 Query: 753 FEEARGFLSEVSETD 767 + +G L + E D Sbjct: 279 SKVIKGSLPLIGEAD 293 >3GSZ-A nrPDB Length = 563 Score = 30.1 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 123 ALALLRWAGKEGAADASALEMVVRA--LGREGQHDAVCALLDETPLPPGSRLDVRAYTTV 180 A L W + A AS + RA GR + AV L TPLP SRLD+ + TV Sbjct: 494 APPLRAWKSRARAVRASLIAQGARAAICGRYLFNWAVKTKLKLTPLPEASRLDLSGWFTV 553 >3H4S-A nrPDB Length = 386 Score = 29.7 bits (65), Expect = 5.1, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 8/82 (9%) Query: 451 VELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQ 510 V+ + D YN I AYG+ GS F +Y ++ G TP L N+L R ++ Sbjct: 80 VQSAVDGYNVCIFAYGQTGSG-KTFTIYGHESNPGLTP--RATKELFNILKR-----DSK 131 Query: 511 SIVSKMRTKGFKPNEQSYSLLL 532 ++ + + + LL Sbjct: 132 RFSFSLKAYMVELYQDTLVDLL 153 >1BF2-A nrPDB Length = 750 Score = 29.3 bits (64), Expect = 6.0, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 36/109 (33%), Gaps = 13/109 (11%) Query: 481 MTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLL-------- 532 +T+ F P T N +V+ + Q+ M F P+ + Y+ Sbjct: 219 VTAVEFLPVQETQNDANDVVP---NSDANQNYWGYMTENYFSPDRR-YAYNKAAGGPTAE 274 Query: 533 -QCYAKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGM 580 Q + + AGI + VY A +W + R LD Sbjct: 275 FQAMVQAFHNAGIKVYMDVVYNHTAEGGTWTSSDPTTATIYSWRGLDNA 323 >3KF9-A nrPDB Length = 149 Score = 29.3 bits (64), Expect = 6.4, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 21/39 (53%) Query: 446 MRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSA 484 MR+ G E ++ +IA + GS T F+ + +M +A Sbjct: 34 MRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFLQMMTA 72 >4IFS-A nrPDB Length = 243 Score = 29.3 bits (64), Expect = 6.8, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 155 DAVCALLDETPLPPGSRLDVRAYTTVLHALSRAGRYE 191 DA+C + L P R D+R Y T LH + Y+ Sbjct: 10 DAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYK 46 >4XMN-D nrPDB Length = 685 Score = 28.9 bits (63), Expect = 9.0, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 46/118 (38%), Gaps = 12/118 (10%) Query: 602 MLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSE--SWEAEK----ILN 655 MLSI + + A E++ ++ LS +++++ A S +E K +L Sbjct: 463 MLSICVEWRLPEIAKEIYTTLGNQMLSA-----HNIIESIANFSRAGKYELVKSYSWLLF 517 Query: 656 QLKCSQTMKPDVVSYNTVI-NGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGY 712 + C + K D N ++ + V Q +L +V + M Y L Y Sbjct: 518 EASCMEGQKLDDPVLNAIVSKNSPAEDDVIIPQDILDCVVTNSMRQTLAPYAVLSQFY 575 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.131 0.366 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,460,215 Number of Sequences: 36641 Number of extensions: 1206235 Number of successful extensions: 4452 Number of sequences better than 10.0: 53 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 67 Number of HSP's that attempted gapping in prelim test: 3802 Number of HSP's gapped (non-prelim): 357 length of query: 786 length of database: 10,336,785 effective HSP length: 105 effective length of query: 681 effective length of database: 6,489,480 effective search space: 4419335880 effective search space used: 4419335880 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)