BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= A4D126 (451 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4CVH-A nrPDB 840 0.0 3F1C-A nrPDB 103 2e-22 4JIS-A nrPDB 102 3e-22 4KT7-A nrPDB 91 1e-18 5HS2-A nrPDB 90 2e-18 1VPA-A nrPDB 89 4e-18 2VSI-A nrPDB 86 3e-17 2XWN-A nrPDB 84 1e-16 2XWM-A nrPDB 83 3e-16 1VGT-A nrPDB 80 2e-15 4NAK-A nrPDB 79 3e-15 2PX7-A nrPDB 77 1e-14 4ZDQ-A nrPDB 74 1e-13 4MYB-A nrPDB 58 7e-09 1VGW-A nrPDB 52 4e-07 1W55-A nrPDB 51 1e-06 5Z09-A nrPDB 48 7e-06 3JUK-A nrPDB 35 0.053 6EZO-E nrPDB 35 0.062 4D48-A nrPDB 33 0.27 2E3D-A nrPDB 33 0.27 3R2W-A nrPDB 33 0.32 5J49-A nrPDB 32 0.55 1JYL-A nrPDB 32 0.62 4Y7U-A nrPDB 32 0.63 5I1F-A nrPDB 32 0.73 2WJF-A nrPDB 32 0.80 5VE7-A nrPDB 31 0.86 2UX8-A nrPDB 31 1.3 1TAR-A nrPDB 30 1.9 2QKX-A nrPDB 30 2.0 4G3P-A nrPDB 30 2.5 3LP4-A nrPDB 28 7.2 2OKV-A nrPDB 28 8.2 6EZ3-A nrPDB 28 8.8 >4CVH-A nrPDB Length = 411 Score = 840 bits (2170), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/409 (100%), Positives = 409/409 (100%) Query: 43 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENM 102 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENM Sbjct: 3 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENM 62 Query: 103 EVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV 162 EVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV Sbjct: 63 EVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV 122 Query: 163 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 222 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI Sbjct: 123 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 182 Query: 223 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERIS 282 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERIS Sbjct: 183 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERIS 242 Query: 283 QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVN 342 QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVN Sbjct: 243 QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVN 302 Query: 343 VTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVK 402 VTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVK Sbjct: 303 VTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVK 362 Query: 403 ERNILLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLLIA 451 ERNILLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLLIA Sbjct: 363 ERNILLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLLIA 411 >3F1C-A nrPDB Length = 246 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 119/240 (49%), Gaps = 6/240 (2%) Query: 47 VAAVLPAGGCGERMG-VPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 + A + AGG G RMG V PKQF P+ +P+I +T++ I+++ E M Sbjct: 4 IYAQILAGGKGTRMGNVSMPKQFLPLNGKPIIVHTVEKFILNTRFDKILISSPKEWMNHA 63 Query: 106 KSIIQKY-QHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEE 164 + I+KY RI ++E G R+ +I NG++ + + L+ ++++ HDAVRPF+ Sbjct: 64 EDNIKKYISDDRIVVIEGGEDRNETIMNGIRFVEK---TYGLTDDDIIVTHDAVRPFLTH 120 Query: 165 GVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYE 224 ++ + + AA E GA + + T+V S + R + PQ+F ++ Sbjct: 121 RIIEENIDAALETGAVDTVIEALDTIVESSNHEVITDIPVRDHMYQGQTPQSFNMKKVFN 180 Query: 225 AYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQE 284 YQ + + T+ ++ L KLV+G K+T DL A +II+ERI+ E Sbjct: 181 HYQNLTPEKKQILTDACKICL-LAGDDVKLVKGEIFNIKITTPYDLKVANAIIQERIANE 239 >4JIS-A nrPDB Length = 247 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 121/243 (49%), Gaps = 13/243 (5%) Query: 47 VAAVLPAGGCGERMG-VPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 + A + AGG G RMG V PKQF P+ +RP+I +T++ I++ E + Sbjct: 4 IYAEILAGGKGSRMGNVNMPKQFLPLNKRPIIIHTVEKFLLNDRFDKILIVSPKEWINHT 63 Query: 106 KSIIQKY--QHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVE 163 K I++K+ Q R+ +VE G R+ SI +G++ + ++ + +V+I HD+VRPF+ Sbjct: 64 KDILKKFIGQDDRLVVVEGGSDRNESIMSGIRYIEKE---FGIQDNDVIITHDSVRPFLT 120 Query: 164 EGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIY 223 ++ + + A ++GA + + T+++ + R + PQ+F + Sbjct: 121 HRIIDENIDAVLQYGAVDTVISAIDTIIASEDQEFISDIPVRDNMYQGQTPQSFRISKLV 180 Query: 224 EAYQQCSDYDLEFGTECLQLALKYCC---TKAKLVEGSPDLWKVTYKRDLYAAESIIKER 280 E Y + SD T+ A K C K KLV G KVT DL A +I++ER Sbjct: 181 ELYNKLSDEQKAVLTD----ACKICSLAGEKVKLVRGEVFNIKVTTPYDLKVANAILQER 236 Query: 281 ISQ 283 ISQ Sbjct: 237 ISQ 239 >4KT7-A nrPDB Length = 237 Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 63/236 (26%), Positives = 113/236 (47%), Gaps = 13/236 (5%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++A++ A G G RM K + + R ++ TL + RV I +I++ + ++ +++K Sbjct: 10 ISAIITAAGSGLRMRSKINKPYIEVGGRKVLEITLDTVSRVKEIDEIILVIRKDDEDIIK 69 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 I++KY I V TR S F GLKAL + E+V+ HD VRPF E + Sbjct: 70 DILEKYDGN-IRYVYGSTTRELSTFEGLKALD--------PQSELVLTHDGVRPFASEEL 120 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAY 226 LK + A +++ A TV D +D++ R + PQAF +IY Y Sbjct: 121 FLKTINALRKNKAVITATKSKDTVKIIDDDMYVDFTPNRDYVYNIQTPQAFDKKLIYAMY 180 Query: 227 QQ--CSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKER 280 ++ S++ + ++ + + K K+V G K+T + D+ A + ++ + Sbjct: 181 EKYLASEFKVTDDSQLFEFFDR--DEKVKVVHGEYSNIKITTQEDIIFANAYLQRK 234 >5HS2-A nrPDB Length = 232 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 120/250 (48%), Gaps = 24/250 (9%) Query: 50 VLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSII 109 V+PA G G+RM K F + P+I +TL+ + I++ + + E + ++ Sbjct: 6 VIPAAGQGKRMKAGRNKLFIELKGDPVIIHTLRVFDSHRQCDKIILVINEQEREHFQQLL 65 Query: 110 QKYQHK-RISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLL 168 Y + I LV G R S++ GLKA+ +++I V++HD RPF++ + Sbjct: 66 SDYPFQTSIELVAGGDERQHSVYKGLKAVKQEKI---------VLVHDGARPFIKHEQID 116 Query: 169 KVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAYQQ 228 +++ A++ GAA P+ T + D + ++ER+ A + PQAF ++ +A+ + Sbjct: 117 ELIAEAEQTGAAILAVPVKDT-IKRVQDLQVSETIERSSLWAVQTPQAFRLSLLMKAHAE 175 Query: 229 CSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQEICVV 288 GT+ L + ++VEGS K+T DL +AE+I Sbjct: 176 AERKGF-LGTDDASLVEQMEGGSVRVVEGSYTNIKLTTPDDLTSAEAI------------ 222 Query: 289 MDTEEDNKHV 298 M++E NKHV Sbjct: 223 MESESGNKHV 232 >1VPA-A nrPDB Length = 234 Score = 89.0 bits (219), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 73/231 (31%), Positives = 115/231 (49%), Gaps = 17/231 (7%) Query: 49 AVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI 108 A+L A G GERM PKQF I R L Y L + I +V+ E EV++ Sbjct: 16 AILLAAGKGERMSENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRREWFEVVEKR 75 Query: 109 IQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLL 168 + + K + +VE G TR +S+ + L+ L K S P V++HD+ RPF+ + + Sbjct: 76 V--FHEKVLGIVEGGDTRSQSVRSALEFL------EKFS-PSYVLVHDSARPFLRKKHVS 126 Query: 169 KVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAYQQ 228 +V+ A+E GAA +V D ++Y + +R PQAF ++++ +A++ Sbjct: 127 EVLRRARETGAATLALKNSDALVRVEND-RIEYIPRKGVYRIL-TPQAFSYEILKKAHEN 184 Query: 229 CSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279 ++ + TE +Q K LVEG P +KVT+K DL A I +E Sbjct: 185 GGEWADD--TEPVQ----KLGVKIALVEGDPLCFKVTFKEDLELARIIARE 229 >2VSI-A nrPDB Length = 236 Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/240 (28%), Positives = 115/240 (47%), Gaps = 14/240 (5%) Query: 47 VAAVLPAGGCGERMGVPT-PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 + A + AGG G RMG+ PKQF + +RP++ +T++ I+ IVV V G+ + Sbjct: 3 IYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHA 62 Query: 106 KSIIQKY---QHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV 162 + ++ KY +RI + + G R+ SI N ++A+ L+ ++V+ HD+VRPF+ Sbjct: 63 EDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAI---DAYRPLTPEDIVVTHDSVRPFI 119 Query: 163 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 222 ++ + A+ H A + V T+V + + RA + PQ F Sbjct: 120 TLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDF 179 Query: 223 YEAYQQCSDYDLEFGTECLQLALKYCCTKAK---LVEGSPDLWKVTYKRDLYAAESIIKE 279 + Y SD + E T+ A K K K L +G K+T DL A+S+I++ Sbjct: 180 MDLYGSLSDEEKEILTD----ACKIFVIKGKDVALAKGEYSNLKITTVTDLKIAKSMIEK 235 >2XWN-A nrPDB Length = 233 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 69/238 (28%), Positives = 117/238 (49%), Gaps = 13/238 (5%) Query: 42 RHPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGEN 101 R V A++PA G GER+ V PK F + + LI + L + +VVAV + Sbjct: 3 REAGEVVAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADR 62 Query: 102 MEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPF 161 + + I+ R +V G R ++ L L S ++PE V++HDA R Sbjct: 63 TDEARQILG----HRAMIVAGGSNRTDTVNLALTVL------SGTAEPEFVLVHDAARAL 112 Query: 162 VEEGVLLKVVTAAKE-HGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFD 220 ++ +VV A ++ + A + PL T+ + A+G + + ERA RA + PQ F D Sbjct: 113 TPPALVARVVEALRDGYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTD 172 Query: 221 VIYEAYQQCSDYDLEFGTECLQLAL-KYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 ++ +YQ+ S DL +L ++ + ++V+G P +K+T K DL A++I+ Sbjct: 173 LLLRSYQRGS-LDLPAAEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229 >2XWM-A nrPDB Length = 223 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 69/233 (29%), Positives = 109/233 (46%), Gaps = 17/233 (7%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 A AV+PA G GER+ PK F + PL+ + L L I IV+AV + Sbjct: 2 ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDES 61 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 K + + + +V GV R S+ L+A + E V++HDA R Sbjct: 62 KLV---FGGEDSVIVSGGVDRTESVALALEAAGD---------AEFVLVHDAARALTPPA 109 Query: 166 VLLKVVTAAKE-HGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYE 224 ++ +VV A KE H A T+ + A+G + + ERA RA + PQ F DV+ Sbjct: 110 LIARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRR 169 Query: 225 AYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 AY + + + T+ L ++ T ++V+G P +K+T DL AE+++ Sbjct: 170 AYARATAGGV---TDDASL-VEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218 >1VGT-A nrPDB Length = 238 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/240 (26%), Positives = 113/240 (47%), Gaps = 15/240 (6%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 V AV+PA G G RM PKQ+ I + ++ +++ AL +K +V+A++ + + Sbjct: 10 VCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQ 69 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 + H +I++V+ G R S+ GLKA + Q V++HDA RP + + Sbjct: 70 --LPLANHPQITVVDGGDERADSVLAGLKAAGDAQW---------VLVHDAARPCLHQDD 118 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADG--CLDYSLERARHRASEMPQAFLFDVIYE 224 L +++ ++ G + V + + G + ++++R + PQ F +++++ Sbjct: 119 LARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHD 178 Query: 225 AYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQE 284 + + E AL+YC +LVEG D KVT DL AE + I QE Sbjct: 179 CLTRALNEGATITDEA--SALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQE 236 >4NAK-A nrPDB Length = 228 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 65/238 (27%), Positives = 113/238 (47%), Gaps = 17/238 (7%) Query: 45 QAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEV 104 ++V+ +L AGG G+RM + PKQ+ P+L +P+ Y+ R+ +K+IVV Sbjct: 3 KSVSVILLAGGQGKRMKMSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCD----PF 58 Query: 105 MKSIIQKYQHK---RISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPF 161 + I ++Y+ +S G R S+++GL+ E +NS E+V IHD+ RP Sbjct: 59 FRDIFEEYEESIDVDLSFAIPGKERQDSVYSGLQ---EIDVNS-----ELVCIHDSARPL 110 Query: 162 VEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDV 221 V + KV+ GAA P +T+ ++D + +L+R + PQ ++ Sbjct: 111 VNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPEL 170 Query: 222 IYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279 + + ++ LE + ++Y + +GS KVT DL AE I+ E Sbjct: 171 LKKGFELVKSEGLEVTDDV--SIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILSE 226 >2PX7-A nrPDB Length = 236 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/233 (29%), Positives = 111/233 (47%), Gaps = 27/233 (11%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 V+ ++PA G G R+G PK F + R L+ +TL A +++VA+ E K Sbjct: 26 VSVLIPAAGNGLRLGR-GPKAFLQVGGRTLLEWTLAAFRDAA---EVLVALP-PGAEPPK 80 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 + + +E G TR S+ L+A S P +V++HD RPFV G+ Sbjct: 81 GLGAVF-------LEGGATRQASVARLLEAA---------SLP-LVLVHDVARPFVSRGL 123 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAY 226 + +V+ AA+ GAA + P+ T+++P + + R R + PQ F ++ EA+ Sbjct: 124 VARVLEAAQRSGAAVPVLPVPDTLMAPEGE-AYGRVVPREAFRLVQTPQGFFTALLREAH 182 Query: 227 QQCSDYDLEFGTEC-LQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIK 278 LE + L AL Y LVEG +K+T+ +DL AE++ + Sbjct: 183 AYARRKGLEASDDAQLVQALGYPVA---LVEGEATAFKITHPQDLVLAEALAR 232 >4ZDQ-A nrPDB Length = 241 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 108/232 (46%), Gaps = 12/232 (5%) Query: 49 AVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI 108 A++P G G R G PKQ+ + R L+ YTL A + +V ++ ++ Sbjct: 12 ALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDACSEFAQTLVVISPDDAHFDA-- 69 Query: 109 IQKYQHKRISLVE-AGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVL 167 +++ R ++ G +R S+ NGL LAE + + V++HDA RP + ++ Sbjct: 70 -RRFAGLRFAVRRCGGASRQASVMNGLIQLAE----FGATDADWVLVHDAARPGITPALI 124 Query: 168 LKVVTAAKEHGAAGAIR-PLVSTVVS-PSADGCLDYSLERARHRASEMPQAFLFDVIYEA 225 ++ A K+ G + P+ T+ P+ ++ + R ++ PQ F ++ +A Sbjct: 125 RTLIGALKDDPVGGIVALPVADTLKRVPAGGDAIERTESRNGLWQAQTPQMFRIGMLRDA 184 Query: 226 YQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 Q+ + E A+++ ++V+GS +KVTY D AE+I+ Sbjct: 185 IQRAQLEGRDLTDEA--SAIEWAGHTPRVVQGSLRNFKVTYPEDFDLAEAIL 234 >4MYB-A nrPDB Length = 261 Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 59/244 (24%), Positives = 97/244 (39%), Gaps = 21/244 (8%) Query: 50 VLPAGGCGERMGVPTPKQFC------PILERPLISYTLQALERVCWIKDIVVAVTGENME 103 ++PA G G RM + PKQ+ IL+ L+ + L I VA+ + Sbjct: 7 IIPAAGIGTRMQLDIPKQYYKLNNGKTILDNTLVKFIDNPL-----FDKIFVAIAASDNF 61 Query: 104 VMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVE 163 S+ Y H +I + G TR S++N L + E + + V +HDA RP V Sbjct: 62 WNNSLY--YNHDKIVVCNGGETRFNSVYNALNVIDERK------NDDWVFVHDAARPCVS 113 Query: 164 EGVLLKVVTAAK-EHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 222 ++ + K H AG + V + +L R ++ PQ + Sbjct: 114 IDSIIDLYEQTKSSHSQAGILAVRAYETVKQVTKNIVVKTLARDNIWLAQTPQLSRLGQL 173 Query: 223 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDL-YAAESIIKERI 281 +A+ C +L AL+ +VE S K+T K DL YA + K + Sbjct: 174 EKAFDFCYSNNLVAKVTDEASALEMFGINPIVVECSKKNIKITTKDDLEYANWQLGKGEL 233 Query: 282 SQEI 285 + ++ Sbjct: 234 NSKL 237 >1VGW-A nrPDB Length = 231 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 41/177 (23%), Positives = 81/177 (45%), Gaps = 5/177 (2%) Query: 49 AVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI 108 A++PA G G R G PKQ+ I + ++ + L ER + VV V+ E+ K + Sbjct: 9 ALIPAAGIGVRFGADKPKQYVEIGSKTVLEHVLGIFERHEAVDLTVVVVSPEDTFADK-V 67 Query: 109 IQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLL 168 + R+ G TR ++ NG+ L E + ++ +++HDA R + L Sbjct: 68 QTAFPQVRV-WKNGGQTRAETVRNGVAKLLETGLAAETDN---ILVHDAARCCLPSEALA 123 Query: 169 KVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEA 225 +++ A G + V+ + + G + +++R+ ++ PQ F +++ A Sbjct: 124 RLIEQAGNAAEGGILAVPVADTLKRAESGQISATVDRSGLWQAQTPQLFQAGLLHRA 180 >1W55-A nrPDB Length = 371 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 54/224 (24%), Positives = 91/224 (40%), Gaps = 29/224 (12%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ ++ A G R KQF + PL Y + L K IV VT N+ MK Sbjct: 4 MSLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKIV--VTSSNITYMK 61 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 + Y+ +E G TR S+ L +L E V++ D R V + + Sbjct: 62 KFTKNYE-----FIEGGDTRAESLKKAL----------ELIDSEFVMVSDVARVLVSKNL 106 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAY 226 +++ + A I P + + D + +L+R + + + PQ ++ +A Sbjct: 107 FDRLI---ENLDKADCITPALKVADTTLFD---NEALQREKIKLIQTPQISKTKLLKKAL 160 Query: 227 QQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDL 270 Q +LEF + +A K VEG + K+T+K DL Sbjct: 161 DQ----NLEFTDDSTAIA--AMGGKIWFVEGEENARKLTFKEDL 198 >5Z09-A nrPDB Length = 409 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 9/75 (12%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 A + A G GER+ T PK F PIL +PLI Y ++ L R C I+DI V V+ +N E Sbjct: 3 AFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYL-RKCGIRDITVIVSSKNKEYF 61 Query: 106 KSIIQKYQHKRISLV 120 + + K IS+V Sbjct: 62 EK-----KLKEISIV 71 >3JUK-A nrPDB Length = 281 Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 7/56 (12%) Query: 50 VLPAGGCGERMGVPT---PKQFCPILERPLISYTL-QALERVCWIKDIVVAVTGEN 101 + PA G G R T PK+ PI+++PLI Y + +A+E C +++ VTG N Sbjct: 6 LFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGC---EVMAIVTGRN 58 >6EZO-E nrPDB Length = 452 Score = 35.0 bits (79), Expect = 0.062, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 7/70 (10%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 AV+ A G G RM T PK P+ +PLI Y L LERV + + IVV +V Sbjct: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR----DVQ 60 Query: 106 KSIIQKYQHK 115 K++ +++ K Sbjct: 61 KALCAEFKMK 70 >4D48-A nrPDB Length = 302 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 3/37 (8%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQ 82 AV+P G G RM T PK+ P++++PLI Y + Sbjct: 11 AVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVN 47 >2E3D-A nrPDB Length = 302 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 3/37 (8%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQ 82 AV+P G G RM T PK+ P++++PLI Y + Sbjct: 11 AVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVN 47 >3R2W-A nrPDB Length = 528 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 12/99 (12%) Query: 44 PQAVAAVLPA-------GGCGERMGVPTPKQFCPIL-ERPLISYTLQALERV--CWIKDI 93 P +++VL GG G MG PK + E + T+Q +E + + D+ Sbjct: 118 PDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDV 177 Query: 94 --VVAVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSI 130 V+ + E K I+QKY H R+ + +R+ I Sbjct: 178 PLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRI 216 >5J49-A nrPDB Length = 301 Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 3/37 (8%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQ 82 AV P G G R T PK+ PI+++PLI Y ++ Sbjct: 15 AVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVE 51 >1JYL-A nrPDB Length = 254 Score = 32.0 bits (71), Expect = 0.62, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 4/54 (7%) Query: 47 VAAVLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAV 97 V A++ A G G R+ TPK + ++PLI Y ++ L+ I DI++ V Sbjct: 26 VKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKG-INDIIIIV 78 >4Y7U-A nrPDB Length = 231 Score = 32.0 bits (71), Expect = 0.63, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 6/60 (10%) Query: 49 AVLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVV--AVTGENME 103 A++ A G GERM + TPK P+ +PLI Y L+AL + ++V+ A G+ +E Sbjct: 3 AMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALA-AAGVTEVVINHAWLGQQIE 61 >5I1F-A nrPDB Length = 302 Score = 31.6 bits (70), Expect = 0.73, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 3/37 (8%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQ 82 AV P G G R T PK+ P++++PLI Y ++ Sbjct: 15 AVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVE 51 >2WJF-A nrPDB Length = 247 Score = 31.6 bits (70), Expect = 0.80, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 384 PSQKM-ENLMQIREFAKEVKERNILLYGLLISYPQD 418 P +K+ EN +Q+RE AKEV ++ YG I Y D Sbjct: 55 PEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPD 90 >5VE7-A nrPDB Length = 302 Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 3/37 (8%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQ 82 AV P G G R T PK+ P++++PLI Y ++ Sbjct: 15 AVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVE 51 >2UX8-A nrPDB Length = 297 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 3/36 (8%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTL 81 AV P G G R T PK+ P+++RPLI Y + Sbjct: 17 AVFPVAGLGTRFLPATKAMPKEMLPVVDRPLIQYAV 52 >1TAR-A nrPDB Length = 401 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 20/122 (16%) Query: 334 QCYNFVCVNVTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQ 393 Q Y + + DF + +S + E S+ +L+ V P Q+ Q Sbjct: 148 QAYRYYDPKTCSLDFTGAMEDISKIPEKSIILLHACAHNPTG------VDPRQE-----Q 196 Query: 394 IREFAKEVKERNILLYGLLISY--------PQDDQKLQESLRQGAIIIASLIKERNSGLI 445 +E A VK+RN+L Y ++Y +D L+ + QG ++ S +N GL Sbjct: 197 WKELASVVKKRNLLAY-FDMAYQGFASGDINRDAWALRHFIEQGIDVVLSQSYAKNMGLY 255 Query: 446 GQ 447 G+ Sbjct: 256 GE 257 >2QKX-A nrPDB Length = 391 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 34/159 (21%), Positives = 65/159 (40%), Gaps = 24/159 (15%) Query: 44 PQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVV-------- 95 P A ++ A G G RM TPK + R ++S+ L A+ ++ + IVV Sbjct: 6 PGDTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRI 65 Query: 96 -AVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVII 154 + GE + + I ++L + + ++ GL AL +D + V++ Sbjct: 66 APLVGELADTLGRTID------VALQDRPLGTGHAVLCGLSALPDDYAGN-------VVV 112 Query: 155 HDAVRPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSP 193 P ++ L ++ A + A+ L +T+ P Sbjct: 113 TSGDTPLLDADTLADLI--ATHRAVSAAVTVLTTTLDDP 149 >4G3P-A nrPDB Length = 501 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 34/159 (21%), Positives = 65/159 (40%), Gaps = 24/159 (15%) Query: 44 PQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVV-------- 95 P A ++ A G G RM TPK + R ++S+ L A+ ++ + IVV Sbjct: 10 PGDTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRI 69 Query: 96 -AVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVII 154 + GE + + I ++L + + ++ GL AL +D + V++ Sbjct: 70 APLVGELADTLGRTID------VALQDRPLGTGHAVLCGLSALPDDYAGN-------VVV 116 Query: 155 HDAVRPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSP 193 P ++ L ++ A + A+ L +T+ P Sbjct: 117 TSGDTPLLDADTLADLI--ATHRAVSAAVTVLTTTLDDP 153 >3LP4-A nrPDB Length = 322 Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 257 GSPDLWKVTYKRDLYAAESIIKERISQEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVT 316 G+P + +TY+ LY E I K + +D E N +G EEV ++ V +T Sbjct: 245 GTPVVGGLTYREGLYITEEIYK----TGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 Query: 317 SEALGHA--GRH 326 G A G H Sbjct: 301 LACFGLAREGNH 312 >2OKV-A nrPDB Length = 209 Score = 28.1 bits (61), Expect = 8.2, Method: Compositional matrix adjust. Identities = 16/67 (23%), Positives = 37/67 (55%), Gaps = 10/67 (14%) Query: 281 ISQEICVVM--DTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNF 338 I + ICV++ E+ K + H++ ++L +++V + +G+H + ++D+ Y Sbjct: 23 IGRGICVLLGISLEDTQKELEHMVRKIL-----NLRVFED---ESGKHWSKSVMDKQYEI 74 Query: 339 VCVNVTT 345 +CV+ T Sbjct: 75 LCVSQFT 81 >6EZ3-A nrPDB Length = 234 Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 208 HRASEMPQAFLFDVIYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYK 267 HR S+ + IY+ + D F CL+++L+ +K K V S ++ T + Sbjct: 107 HRFSDFKNNIYYIDIYKTIVDQFNTDSNFKNSCLKMSLQALQSKGKNVNTSIEITDETLE 166 Query: 268 RDLYAAESIIKE 279 YAA+ ++ E Sbjct: 167 ---YAAQYVLAE 175 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4CVH-A nrPDB 643 0.0 3F1C-A nrPDB 274 6e-74 4JIS-A nrPDB 272 2e-73 5HS2-A nrPDB 256 1e-68 1VGT-A nrPDB 252 3e-67 2VSI-A nrPDB 247 7e-66 4ZDQ-A nrPDB 241 5e-64 4NAK-A nrPDB 237 9e-63 4KT7-A nrPDB 234 8e-62 4MYB-A nrPDB 233 1e-61 2XWM-A nrPDB 230 8e-61 2XWN-A nrPDB 220 8e-58 1VPA-A nrPDB 220 1e-57 1VGW-A nrPDB 211 4e-55 2PX7-A nrPDB 206 2e-53 1W55-A nrPDB 181 6e-46 5Z09-A nrPDB 67 2e-11 Sequences not found previously or not previously below threshold: 4G3P-A nrPDB 64 9e-11 2QKX-A nrPDB 64 9e-11 5VMK-A nrPDB 58 9e-09 2V0L-A nrPDB 57 2e-08 1HM0-A nrPDB 54 1e-07 2CU2-A nrPDB 53 2e-07 3FWW-A nrPDB 52 4e-07 2X5Z-A nrPDB 52 6e-07 1JYL-A nrPDB 51 1e-06 1MC3-A nrPDB 50 2e-06 3PKP-A nrPDB 50 2e-06 1H5S-D nrPDB 50 2e-06 3ZLK-A nrPDB 49 3e-06 2OI7-A nrPDB 49 5e-06 1FWY-A nrPDB 49 5e-06 4Y7U-A nrPDB 49 5e-06 2MZB-A nrPDB 47 1e-05 5IDS-A nrPDB 47 2e-05 6EZO-E nrPDB 47 2e-05 4HO3-A nrPDB 46 3e-05 5IFY-A nrPDB 46 3e-05 1H4E-A nrPDB 46 4e-05 1LVW-A nrPDB 45 4e-05 4D48-A nrPDB 45 5e-05 6N0U-A nrPDB 45 6e-05 6B5K-A nrPDB 45 7e-05 2E3D-A nrPDB 45 9e-05 4MND-A nrPDB 44 1e-04 1WVC-A nrPDB 44 2e-04 5B04-E nrPDB 42 6e-04 4JD0-A nrPDB 41 8e-04 4ECM-A nrPDB 40 0.002 3NGW-A nrPDB 40 0.003 5I1F-A nrPDB 40 0.003 2E8B-A nrPDB 39 0.004 6I7T-I nrPDB 39 0.004 2UX8-A nrPDB 39 0.004 5J49-A nrPDB 39 0.005 3JUK-A nrPDB 39 0.007 5XHW-A nrPDB 37 0.012 5VE7-A nrPDB 37 0.019 4BQH-A nrPDB 36 0.030 6JLY-I nrPDB 36 0.043 4BMA-A nrPDB 35 0.091 2WJF-A nrPDB 34 0.13 3R2W-A nrPDB 34 0.21 1VM8-A nrPDB 33 0.21 1JV1-A nrPDB 33 0.23 2I5K-A nrPDB 33 0.33 2YQJ-A nrPDB 33 0.35 6HIV-DL nrPDB 33 0.36 6CKJ-A nrPDB 31 0.88 3RHO-A nrPDB 31 0.93 4GIJ-A nrPDB 31 1.0 1Q3S-A nrPDB 31 1.4 5OMS-A nrPDB 30 1.5 6DD5-A nrPDB 30 1.6 2QSJ-A nrPDB 30 1.8 5IEF-A nrPDB 30 1.9 5HJR-A nrPDB 30 1.9 3DR5-A nrPDB 30 2.1 3H4P-a nrPDB 30 2.1 6MSK-X nrPDB 30 2.2 2PA4-A nrPDB 30 2.2 5W6J-A nrPDB 30 2.5 3OC9-A nrPDB 30 3.0 1B74-A nrPDB 29 3.1 2W3Z-A nrPDB 29 3.5 4FCU-A nrPDB 29 3.8 5Y9S-A nrPDB 29 3.8 4XCI-A nrPDB 29 4.1 3LK5-A nrPDB 29 4.7 >4CVH-A nrPDB Length = 411 Score = 643 bits (1658), Expect = 0.0, Method: Composition-based stats. Identities = 409/409 (100%), Positives = 409/409 (100%) Query: 43 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENM 102 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENM Sbjct: 3 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENM 62 Query: 103 EVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV 162 EVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV Sbjct: 63 EVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV 122 Query: 163 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 222 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI Sbjct: 123 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 182 Query: 223 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERIS 282 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERIS Sbjct: 183 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERIS 242 Query: 283 QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVN 342 QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVN Sbjct: 243 QEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVN 302 Query: 343 VTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVK 402 VTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVK Sbjct: 303 VTTSDFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVK 362 Query: 403 ERNILLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLLIA 451 ERNILLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLLIA Sbjct: 363 ERNILLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLLIA 411 >3F1C-A nrPDB Length = 246 Score = 274 bits (700), Expect = 6e-74, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 119/240 (49%), Gaps = 6/240 (2%) Query: 47 VAAVLPAGGCGERMG-VPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 + A + AGG G RMG V PKQF P+ +P+I +T++ I+++ E M Sbjct: 4 IYAQILAGGKGTRMGNVSMPKQFLPLNGKPIIVHTVEKFILNTRFDKILISSPKEWMNHA 63 Query: 106 KSIIQKY-QHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEE 164 + I+KY RI ++E G R+ +I NG++ + + L+ ++++ HDAVRPF+ Sbjct: 64 EDNIKKYISDDRIVVIEGGEDRNETIMNGIRFVEK---TYGLTDDDIIVTHDAVRPFLTH 120 Query: 165 GVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYE 224 ++ + + AA E GA + + T+V S + R + PQ+F ++ Sbjct: 121 RIIEENIDAALETGAVDTVIEALDTIVESSNHEVITDIPVRDHMYQGQTPQSFNMKKVFN 180 Query: 225 AYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQE 284 YQ + + T+ ++ L KLV+G K+T DL A +II+ERI+ E Sbjct: 181 HYQNLTPEKKQILTDACKICL-LAGDDVKLVKGEIFNIKITTPYDLKVANAIIQERIANE 239 >4JIS-A nrPDB Length = 247 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 70/242 (28%), Positives = 120/242 (49%), Gaps = 7/242 (2%) Query: 45 QAVAAVLPAGGCGERMG-VPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENME 103 + A + AGG G RMG V PKQF P+ +RP+I +T++ I++ E + Sbjct: 2 GMIYAEILAGGKGSRMGNVNMPKQFLPLNKRPIIIHTVEKFLLNDRFDKILIVSPKEWIN 61 Query: 104 VMKSIIQKY--QHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPF 161 K I++K+ Q R+ +VE G R+ SI +G++ + ++ + +V+I HD+VRPF Sbjct: 62 HTKDILKKFIGQDDRLVVVEGGSDRNESIMSGIRYIEKE---FGIQDNDVIITHDSVRPF 118 Query: 162 VEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDV 221 + ++ + + A ++GA + + T+++ + R + PQ+F Sbjct: 119 LTHRIIDENIDAVLQYGAVDTVISAIDTIIASEDQEFISDIPVRDNMYQGQTPQSFRISK 178 Query: 222 IYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERI 281 + E Y + SD T+ ++ K KLV G KVT DL A +I++ERI Sbjct: 179 LVELYNKLSDEQKAVLTDACKI-CSLAGEKVKLVRGEVFNIKVTTPYDLKVANAILQERI 237 Query: 282 SQ 283 SQ Sbjct: 238 SQ 239 >5HS2-A nrPDB Length = 232 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 67/251 (26%), Positives = 120/251 (47%), Gaps = 24/251 (9%) Query: 49 AVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI 108 V+PA G G+RM K F + P+I +TL+ + I++ + + E + + Sbjct: 5 VVIPAAGQGKRMKAGRNKLFIELKGDPVIIHTLRVFDSHRQCDKIILVINEQEREHFQQL 64 Query: 109 IQKYQHK-RISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVL 167 + Y + I LV G R S++ GLKA+ +++ +V++HD RPF++ + Sbjct: 65 LSDYPFQTSIELVAGGDERQHSVYKGLKAVKQEK---------IVLVHDGARPFIKHEQI 115 Query: 168 LKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAYQ 227 +++ A++ GAA P+ T+ D + ++ER+ A + PQAF ++ +A+ Sbjct: 116 DELIAEAEQTGAAILAVPVKDTIKRV-QDLQVSETIERSSLWAVQTPQAFRLSLLMKAHA 174 Query: 228 QCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQEICV 287 + GT+ L + ++VEGS K+T DL +AE+I Sbjct: 175 EAERKGF-LGTDDASLVEQMEGGSVRVVEGSYTNIKLTTPDDLTSAEAI----------- 222 Query: 288 VMDTEEDNKHV 298 M++E NKHV Sbjct: 223 -MESESGNKHV 232 >1VGT-A nrPDB Length = 238 Score = 252 bits (643), Expect = 3e-67, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 112/240 (46%), Gaps = 15/240 (6%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 V AV+PA G G RM PKQ+ I + ++ +++ AL +K +V+A++ + + Sbjct: 10 VCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQ 69 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 + H +I++V+ G R S+ GLKA + V++HDA RP + + Sbjct: 70 --LPLANHPQITVVDGGDERADSVLAGLKAAG---------DAQWVLVHDAARPCLHQDD 118 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADG--CLDYSLERARHRASEMPQAFLFDVIYE 224 L +++ ++ G + V + + G + ++++R + PQ F +++++ Sbjct: 119 LARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHD 178 Query: 225 AYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERISQE 284 + + E AL+YC +LVEG D KVT DL AE + I QE Sbjct: 179 CLTRALNEGATITDEA--SALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQE 236 >2VSI-A nrPDB Length = 236 Score = 247 bits (631), Expect = 7e-66, Method: Composition-based stats. Identities = 64/237 (27%), Positives = 113/237 (47%), Gaps = 8/237 (3%) Query: 47 VAAVLPAGGCGERMG-VPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 + A + AGG G RMG PKQF + +RP++ +T++ I+ IVV V G+ + Sbjct: 3 IYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHA 62 Query: 106 KSIIQKY---QHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFV 162 + ++ KY +RI + + G R+ SI N ++A+ L+ ++V+ HD+VRPF+ Sbjct: 63 EDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAID---AYRPLTPEDIVVTHDSVRPFI 119 Query: 163 EEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVI 222 ++ + A+ H A + V T+V + + RA + PQ F Sbjct: 120 TLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDF 179 Query: 223 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279 + Y SD + E T+ ++ + L +G K+T DL A+S+I++ Sbjct: 180 MDLYGSLSDEEKEILTDACKIFV-IKGKDVALAKGEYSNLKITTVTDLKIAKSMIEK 235 >4ZDQ-A nrPDB Length = 241 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 57/234 (24%), Positives = 109/234 (46%), Gaps = 12/234 (5%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 + A++P G G R G PKQ+ + R L+ YTL A + +V ++ ++ Sbjct: 10 LFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDACSEFAQTLVVISPDDAHFDA 69 Query: 107 SIIQKYQHKRISLVE-AGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 +++ R ++ G +R S+ NGL LAE + + V++HDA RP + Sbjct: 70 ---RRFAGLRFAVRRCGGASRQASVMNGLIQLAE----FGATDADWVLVHDAARPGITPA 122 Query: 166 VLLKVVTAAKEHGAAGAIR-PLVSTVVS-PSADGCLDYSLERARHRASEMPQAFLFDVIY 223 ++ ++ A K+ G + P+ T+ P+ ++ + R ++ PQ F ++ Sbjct: 123 LIRTLIGALKDDPVGGIVALPVADTLKRVPAGGDAIERTESRNGLWQAQTPQMFRIGMLR 182 Query: 224 EAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 +A Q+ + E A+++ ++V+GS +KVTY D AE+I+ Sbjct: 183 DAIQRAQLEGRDLTDEA--SAIEWAGHTPRVVQGSLRNFKVTYPEDFDLAEAIL 234 >4NAK-A nrPDB Length = 228 Score = 237 bits (604), Expect = 9e-63, Method: Composition-based stats. Identities = 62/238 (26%), Positives = 110/238 (46%), Gaps = 17/238 (7%) Query: 45 QAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEV 104 ++V+ +L AGG G+RM + PKQ+ P+L +P+ Y+ R+ +K+IVV Sbjct: 3 KSVSVILLAGGQGKRMKMSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDP----F 58 Query: 105 MKSIIQKYQHK---RISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPF 161 + I ++Y+ +S G R S+++GL+ + E+V IHD+ RP Sbjct: 59 FRDIFEEYEESIDVDLSFAIPGKERQDSVYSGLQEID--------VNSELVCIHDSARPL 110 Query: 162 VEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDV 221 V + KV+ GAA P +T+ ++D + +L+R + PQ ++ Sbjct: 111 VNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPEL 170 Query: 222 IYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279 + + ++ LE + ++Y + +GS KVT DL AE I+ E Sbjct: 171 LKKGFELVKSEGLEVTDDV--SIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILSE 226 >4KT7-A nrPDB Length = 237 Score = 234 bits (596), Expect = 8e-62, Method: Composition-based stats. Identities = 62/234 (26%), Positives = 108/234 (46%), Gaps = 9/234 (3%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++A++ A G G RM K + + R ++ TL + RV I +I++ + ++ +++K Sbjct: 10 ISAIITAAGSGLRMRSKINKPYIEVGGRKVLEITLDTVSRVKEIDEIILVIRKDDEDIIK 69 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 I++KY I V TR S F GLKAL + E+V+ HD VRPF E + Sbjct: 70 DILEKYDGN-IRYVYGSTTRELSTFEGLKALD--------PQSELVLTHDGVRPFASEEL 120 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAY 226 LK + A +++ A TV D +D++ R + PQAF +IY Y Sbjct: 121 FLKTINALRKNKAVITATKSKDTVKIIDDDMYVDFTPNRDYVYNIQTPQAFDKKLIYAMY 180 Query: 227 QQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKER 280 ++ + + + K K+V G K+T + D+ A + ++ + Sbjct: 181 EKYLASEFKVTDDSQLFEFFDRDEKVKVVHGEYSNIKITTQEDIIFANAYLQRK 234 >4MYB-A nrPDB Length = 261 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 56/241 (23%), Positives = 95/241 (39%), Gaps = 11/241 (4%) Query: 48 AAVLPAGGCGERMGVPTPKQFCPIL-ERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++PA G G RM + PKQ+ + + ++ TL I VA+ + Sbjct: 5 YVIIPAAGIGTRMQLDIPKQYYKLNNGKTILDNTLVKFIDNPLFDKIFVAIAASDNFWNN 64 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 S+ Y H +I + G TR S++N L + E + + V +HDA RP V Sbjct: 65 SLY--YNHDKIVVCNGGETRFNSVYNALNVIDERK------NDDWVFVHDAARPCVSIDS 116 Query: 167 LLKVVTAAKE-HGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEA 225 ++ + K H AG + V + +L R ++ PQ + +A Sbjct: 117 IIDLYEQTKSSHSQAGILAVRAYETVKQVTKNIVVKTLARDNIWLAQTPQLSRLGQLEKA 176 Query: 226 YQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAA-ESIIKERISQE 284 + C +L AL+ +VE S K+T K DL A + K ++ + Sbjct: 177 FDFCYSNNLVAKVTDEASALEMFGINPIVVECSKKNIKITTKDDLEYANWQLGKGELNSK 236 Query: 285 I 285 + Sbjct: 237 L 237 >2XWM-A nrPDB Length = 223 Score = 230 bits (587), Expect = 8e-61, Method: Composition-based stats. Identities = 67/233 (28%), Positives = 105/233 (45%), Gaps = 17/233 (7%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 A AV+PA G GER+ PK F + PL+ + L L I IV+AV + Sbjct: 2 ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDES 61 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 K + + + +V GV R S+ L+A E V++HDA R Sbjct: 62 KLV---FGGEDSVIVSGGVDRTESVALALEAAG---------DAEFVLVHDAARALTPPA 109 Query: 166 VLLKVVTAAKE-HGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYE 224 ++ +VV A KE H A T+ + A+G + + ERA RA + PQ F DV+ Sbjct: 110 LIARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRR 169 Query: 225 AYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 AY + + + ++ T ++V+G P +K+T DL AE+++ Sbjct: 170 AYARATAGGVT----DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218 >2XWN-A nrPDB Length = 233 Score = 220 bits (561), Expect = 8e-58, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 114/237 (48%), Gaps = 11/237 (4%) Query: 42 RHPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGEN 101 R V A++PA G GER+ V PK F + + LI + L + +VVAV + Sbjct: 3 REAGEVVAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADR 62 Query: 102 MEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPF 161 + + I+ R +V G R ++ L L S ++PE V++HDA R Sbjct: 63 TDEARQIL----GHRAMIVAGGSNRTDTVNLALTVL------SGTAEPEFVLVHDAARAL 112 Query: 162 VEEGVLLKVVTAAKE-HGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFD 220 ++ +VV A ++ + A + PL T+ + A+G + + ERA RA + PQ F D Sbjct: 113 TPPALVARVVEALRDGYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTD 172 Query: 221 VIYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 ++ +YQ+ S +++ + ++V+G P +K+T K DL A++I+ Sbjct: 173 LLLRSYQRGSLDLPAAEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229 >1VPA-A nrPDB Length = 234 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 70/232 (30%), Positives = 112/232 (48%), Gaps = 17/232 (7%) Query: 48 AAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKS 107 A+L A G GERM PKQF I R L Y L + I +V+ E EV++ Sbjct: 15 VAILLAAGKGERMSENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRREWFEVVEK 74 Query: 108 IIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVL 167 + + K + +VE G TR +S+ + L+ L + P V++HD+ RPF+ + + Sbjct: 75 RV--FHEKVLGIVEGGDTRSQSVRSALEFLEKFS-------PSYVLVHDSARPFLRKKHV 125 Query: 168 LKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAYQ 227 +V+ A+E GAA +V D ++Y R PQAF ++++ +A++ Sbjct: 126 SEVLRRARETGAATLALKNSDALVRVEND-RIEYIP-RKGVYRILTPQAFSYEILKKAHE 183 Query: 228 QCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279 ++ + TE ++ K LVEG P +KVT+K DL A I +E Sbjct: 184 NGGEWADD--TEP----VQKLGVKIALVEGDPLCFKVTFKEDLELARIIARE 229 >1VGW-A nrPDB Length = 231 Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats. Identities = 48/229 (20%), Positives = 99/229 (43%), Gaps = 9/229 (3%) Query: 49 AVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI 108 A++PA G G R G PKQ+ I + ++ + L ER + VV V+ E+ K + Sbjct: 9 ALIPAAGIGVRFGADKPKQYVEIGSKTVLEHVLGIFERHEAVDLTVVVVSPEDTFADK-V 67 Query: 109 IQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLL 168 + R+ G TR ++ NG+ L E + ++ +++HDA R + L Sbjct: 68 QTAFPQVRV-WKNGGQTRAETVRNGVAKLLETGLAAETDN---ILVHDAARCCLPSEALA 123 Query: 169 KVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAYQQ 228 +++ A G + V+ + + G + +++R+ ++ PQ F +++ A Sbjct: 124 RLIEQAGNAAEGGILAVPVADTLKRAESGQISATVDRSGLWQAQTPQLFQAGLLHRALAA 183 Query: 229 CSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 + + A++ + L++G K+T +D Y ++ Sbjct: 184 ENLGGIT----DEASAVEKLGVRPLLIQGDARNLKLTQPQDAYIVRLLL 228 >2PX7-A nrPDB Length = 236 Score = 206 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 62/233 (26%), Positives = 108/233 (46%), Gaps = 25/233 (10%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 V+ ++PA G G R+G PK F + R L+ +TL A +++VA+ E Sbjct: 25 EVSVLIPAAGNGLRLGRG-PKAFLQVGGRTLLEWTLAAFRDAA---EVLVALPP-GAEPP 79 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 K + + +E G TR S+ L+A + +V++HD RPFV G Sbjct: 80 KGLGAVF-------LEGGATRQASVARLLEAASLP----------LVLVHDVARPFVSRG 122 Query: 166 VLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEA 225 ++ +V+ AA+ GAA + P+ T+++P + + R R + PQ F ++ EA Sbjct: 123 LVARVLEAAQRSGAAVPVLPVPDTLMAPEGE-AYGRVVPREAFRLVQTPQGFFTALLREA 181 Query: 226 YQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIK 278 + LE + ++ LVEG +K+T+ +DL AE++ + Sbjct: 182 HAYARRKGLEASDDA--QLVQALGYPVALVEGEATAFKITHPQDLVLAEALAR 232 >1W55-A nrPDB Length = 371 Score = 181 bits (459), Expect = 6e-46, Method: Composition-based stats. Identities = 54/226 (23%), Positives = 90/226 (39%), Gaps = 29/226 (12%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 ++ ++ A G R KQF + PL Y + L K IVV T N+ M Sbjct: 3 EMSLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVV--TSSNITYM 60 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 K + Y+ +E G TR S+ L+ L E V++ D R V + Sbjct: 61 KKFTKNYE-----FIEGGDTRAESLKKALE----------LIDSEFVMVSDVARVLVSKN 105 Query: 166 VLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEA 225 + +++ A I P + + D + +L+R + + + PQ ++ +A Sbjct: 106 LFDRLIE---NLDKADCITPALKVADTTLFD---NEALQREKIKLIQTPQISKTKLLKKA 159 Query: 226 YQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLY 271 Q +LEF + +A K VEG + K+T+K DL Sbjct: 160 LDQ----NLEFTDDSTAIA--AMGGKIWFVEGEENARKLTFKEDLK 199 >5Z09-A nrPDB Length = 409 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 20/163 (12%) Query: 47 VAAVLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENME 103 + A + A G GER+ PK F PIL +PLI Y ++ L R C I+DI V V+ +N E Sbjct: 1 MKAFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYL-RKCGIRDITVIVSSKNKE 59 Query: 104 VMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVE 163 + ++ IS+V +K +++K + ++I D F Sbjct: 60 YFEKKLK-----EISIVTQKDD--------IKGTGAAILSAKFNDEALIINGDLF--FSN 104 Query: 164 EGVLLKVVTAAKEHGAAGAIRPLVS-TVVSPSADGCLDYSLER 205 E + ++T + + V+ L +E+ Sbjct: 105 EKEICNIITLKENAIIGVKVSNPKDYGVLVLDNQNNLSKIIEK 147 >4G3P-A nrPDB Length = 501 Score = 64.4 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 76/212 (35%), Gaps = 30/212 (14%) Query: 44 PQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENME 103 P A ++ A G G RM TPK + R ++S+ L A+ ++ + ++V + ++ Sbjct: 10 PGDTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAP-QRLIVVLGHDHQR 68 Query: 104 VMKSIIQKYQHKRISLVEAGVTR----HRSIFNGLKALAEDQINSKLSKPEVVIIHDAVR 159 + + + ++ A R ++ GL AL +D + V++ Sbjct: 69 IAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGN-------VVVTSGDT 121 Query: 160 PFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASE----MPQ 215 P ++ L ++ + AA + T+ P G + + + E P Sbjct: 122 PLLDADTLADLIATHRAVSAAVTVLTT--TLDDPFGYGRILRTQDHEVMAIVEQTDATPS 179 Query: 216 ------------AFLFDVIYEAYQQCSDYDLE 235 AF + A + S + + Sbjct: 180 QREIREVNAGVYAFDIAALRSALSRLSSNNAQ 211 >2QKX-A nrPDB Length = 391 Score = 64.4 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 76/212 (35%), Gaps = 30/212 (14%) Query: 44 PQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENME 103 P A ++ A G G RM TPK + R ++S+ L A+ ++ + ++V + ++ Sbjct: 6 PGDTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAP-QRLIVVLGHDHQR 64 Query: 104 VMKSIIQKYQHKRISLVEAGVTR----HRSIFNGLKALAEDQINSKLSKPEVVIIHDAVR 159 + + + ++ A R ++ GL AL +D + V++ Sbjct: 65 IAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGN-------VVVTSGDT 117 Query: 160 PFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASE----MPQ 215 P ++ L ++ + AA + T+ P G + + + E P Sbjct: 118 PLLDADTLADLIATHRAVSAAVTVLTT--TLDDPFGYGRILRTQDHEVMAIVEQTDATPS 175 Query: 216 ------------AFLFDVIYEAYQQCSDYDLE 235 AF + A + S + + Sbjct: 176 QREIREVNAGVYAFDIAALRSALSRLSSNNAQ 207 >5VMK-A nrPDB Length = 462 Score = 57.8 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 36/233 (15%), Positives = 85/233 (36%), Gaps = 33/233 (14%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 + ++ A G G RM PK P+ RPL+ + ++ + + ++ + G + + Sbjct: 10 STTVIILAAGKGTRMRSQLPKVLQPLAGRPLLGHVIKT--AKQLLAENIITIYGHGGDHV 67 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 K + + I VE + + G A+ +++ D P V + Sbjct: 68 KK---TFAQENIQWVE----QAEQLGTG-HAVQMTLPVLPKDGISLILYGDV--PLVRQT 117 Query: 166 VLLKVVTAAKEHGAAGAIRPLVSTV---VSPSADGCLDYSLERARHRASEMP-QAFLFDV 221 L +++ + + G + + DG + +E ++ Q + Sbjct: 118 TLEQLIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGI 177 Query: 222 -------IYEAYQQCSDYDLE---FGTECLQLA----LKYCCTKAKL---VEG 257 ++E + S+ + + + T+ + +A L+ + +L VEG Sbjct: 178 YCVSNAKLHEWLPKLSNENAQGEYYLTDIVAMAVADGLEIASIQPELAFEVEG 230 >2V0L-A nrPDB Length = 456 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 66/167 (39%), Gaps = 16/167 (9%) Query: 45 QAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEV 104 +A++AV+ A G G RM PK I +P++ + + + + + G ++ Sbjct: 4 KALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDT--AHQLGSENIHLIYGHGGDL 61 Query: 105 MKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEE 164 M++ + ++++ V T + ++ A K ++ VV+ DA P + + Sbjct: 62 MRTHLAN---EQVNWVL--QTEQLGTAHAVQQAA---PFFKDNENIVVLYGDA--PLITK 111 Query: 165 GVLLKVVTAAKEHGAAGAIR----PLVSTVVSPSADGCLDYSLERAR 207 L K++ A E+G A P + + ++ Sbjct: 112 ETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDA 158 >1HM0-A nrPDB Length = 468 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 54/164 (32%), Gaps = 14/164 (8%) Query: 49 AVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI 108 A++ A G G RM PK + ++ + +++ + K + V + Sbjct: 14 AIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQPEKTVTVV------GHKAEL 67 Query: 109 IQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLL 168 +++ + V T+ + G + + I LS +VI D P + L Sbjct: 68 VEEVLAGQTEFV----TQSEQLGTGHAVMMTEPILEGLSGHTLVIAGDT--PLITGESLK 121 Query: 169 KVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASE 212 ++ H I +P G + + R E Sbjct: 122 NLIDFHINHKNVATILTA--ETDNPFGYGRIVRNDNAEVLRIVE 163 >2CU2-A nrPDB Length = 337 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 57/169 (33%), Gaps = 17/169 (10%) Query: 47 VAAVLPAGGCGERM----GVPTPKQFCPI-LERPLISYTLQALERVCWIKDIVVAVTGEN 101 A++ AGG GER+ PK F P+ + L+ TL+ L + + ++AV + Sbjct: 3 TYALVMAGGRGERLWPLSREDRPKPFLPLFEGKTLLEATLERLAPLVPPERTLLAVRRDQ 62 Query: 102 MEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGL-KALAEDQINSKLSKPEVVIIHDAVRP 160 V + R+ L G ++ G+ +AL E + + + D Sbjct: 63 EAVAR---PYADGIRLLLEPLGRDTAGAVLLGVAEALKEGAERLLVLPADHYVGDDEA-- 117 Query: 161 FVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHR 209 L ++ AA+E P + R Sbjct: 118 --YREALATMLEAAEEGFVVALGLRPT----RPETEYGYIRLGPREGAW 160 >3FWW-A nrPDB Length = 456 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 35/255 (13%), Positives = 73/255 (28%), Gaps = 17/255 (6%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 +++ V+ A G G RM PK P+ +P++ + + A ++ V V G E++ Sbjct: 5 SMSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGA--QHVHLVYGHGGELL 62 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 K + + E G + ++++++ V P + Sbjct: 63 KKTLADPSLNWVLQAE---------QLGTGHAMQQAAPHFADDEDILMLYGDV-PLISVD 112 Query: 166 VLLKVVTAAKEHGAAGAIR----PLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDV 221 L +++ A E G P + + + A + Sbjct: 113 TLQRLLAAKPEGGIGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGI 172 Query: 222 IYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERI 281 + + + L Y L + L E + Sbjct: 173 LVANGRDLKRW-LSLLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQ 231 Query: 282 SQEICVVMDTEEDNK 296 + V TE+ K Sbjct: 232 LSALERVFQTEQAEK 246 >2X5Z-A nrPDB Length = 336 Score = 51.7 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 47 VAAVLPAGGCGERM----GVPTPKQFCPI-LERPLISYTLQALERVCWIKDIVVAVTGEN 101 + A++ AGG GER TPKQF + + L+ +T + + KD++V + Sbjct: 2 MKALILAGGSGERFWPLSTPETPKQFLKLFGNKSLMRWTFERVLEEMDPKDVIVVTHKDY 61 Query: 102 MEVMKSIIQKYQHKRIS 118 +E K + + + I Sbjct: 62 VERTKKELPELPDENII 78 >1JYL-A nrPDB Length = 254 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 41 GRHPQA--VAAVLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVV 95 G H + V A++ A G G R+ TPK + ++PLI Y ++ + I DI++ Sbjct: 18 GSHMKEIRVKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIE-FLKEKGINDIII 76 Query: 96 AV 97 V Sbjct: 77 IV 78 >1MC3-A nrPDB Length = 296 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ KQ PI ++P+I Y L L I++I++ T E+ + Sbjct: 7 IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAG-IREILIITTPEDKGYFQ 65 Query: 107 SIIQK 111 ++ Sbjct: 66 RLLGD 70 >3PKP-A nrPDB Length = 292 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ + KQ PI ++P+I Y L L I+DI++ T ++ + Sbjct: 7 IILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAG-IRDILIISTPQDTPRFQ 65 Query: 107 SIIQK 111 ++ Sbjct: 66 QLLGD 70 >1H5S-D nrPDB Length = 293 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ + KQ PI ++P+I Y L L I+DI++ T ++ + Sbjct: 7 IILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAG-IRDILIISTPQDTPRFQ 65 Query: 107 SIIQK 111 ++ Sbjct: 66 QLLGD 70 >3ZLK-A nrPDB Length = 303 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERMGVP---TPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ KQ P+ ++P+I Y L L I++I++ T ++ + Sbjct: 16 IILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAG-IREILIISTPQDTPRFQ 74 Query: 107 SIIQK 111 ++ Sbjct: 75 QLLGD 79 >2OI7-A nrPDB Length = 456 Score = 49.0 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 31/255 (12%), Positives = 71/255 (27%), Gaps = 17/255 (6%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 A++ V+ A G G RM PK + + ++ + + A + +V G ++ Sbjct: 5 AMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDL--- 61 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 + Q + ++ V G + ++++++ V P + Sbjct: 62 --LKQALKDDNLNWVLQAEQ------LGTGHAMQQAAPFFADDEDILMLYGDV-PLISVE 112 Query: 166 VLLKVVTAAKEHGAAGAIRPLVSTV----VSPSADGCLDYSLERARHRASEMPQAFLFDV 221 L ++ A + G L ++ + Q + Sbjct: 113 TLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGI 172 Query: 222 IYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERI 281 + + L T Y L + + L E + Sbjct: 173 LIANGADMKRW-LAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQ 231 Query: 282 SQEICVVMDTEEDNK 296 + V +E+ K Sbjct: 232 LSRLERVYQSEQAEK 246 >1FWY-A nrPDB Length = 331 Score = 49.0 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 31/255 (12%), Positives = 71/255 (27%), Gaps = 17/255 (6%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 A++ V+ A G G RM PK + + ++ + + A + +V G ++ Sbjct: 5 AMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDL--- 61 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 + Q + ++ V G + ++++++ V P + Sbjct: 62 --LKQALKDDNLNWVLQAEQ------LGTGHAMQQAAPFFADDEDILMLYGDV-PLISVE 112 Query: 166 VLLKVVTAAKEHGAAGAIRPLVSTV----VSPSADGCLDYSLERARHRASEMPQAFLFDV 221 L ++ A + G L ++ + Q + Sbjct: 113 TLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGI 172 Query: 222 IYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKERI 281 + + L T Y L + + L E + Sbjct: 173 LIANGADMKRW-LAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQ 231 Query: 282 SQEICVVMDTEEDNK 296 + V +E+ K Sbjct: 232 LSRLERVYQSEQAEK 246 >4Y7U-A nrPDB Length = 231 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 6/58 (10%) Query: 47 VAAVLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGEN 101 + A++ A G GERM TPK P+ +PLI Y L+AL + V + Sbjct: 1 MKAMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALAAAGVTE---VVINHAW 55 >2MZB-A nrPDB Length = 196 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 38/233 (16%), Positives = 79/233 (33%), Gaps = 40/233 (17%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 + A++ AGG G RMG K + R LI Y + L + + +I +A + + + Sbjct: 1 MDALIMAGGKGTRMG-GVEKPLIKLCGRCLIDYVVSPLLKSK-VNNIFIATSPNTPKTKE 58 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 I Y+ + +V S ++ L E S+P +V+ D + ++ + Sbjct: 59 YINSAYKDYKNIVVI-----DTSGKGYIEDLNECIGYF--SEPFLVVSSDLIN--LKSKI 109 Query: 167 LLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYEAY 226 + +V A ++ ++ + +P Y Sbjct: 110 INSIVDYFYCIKAKTPDVEALAVMIPKE------KYPNPSIDFNGLVPAGINVVSPKHGY 163 Query: 227 QQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279 Q+ ++ E + + + K DL AE ++K+ Sbjct: 164 QK---EEIMVIDELI--------------------FNINTKDDLKLAEMLLKK 193 >5IDS-A nrPDB Length = 302 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERMGVP---TPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ KQ P+ ++P+I Y L L ++D++V T ++ + Sbjct: 15 IILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAG-MRDVLVISTPQDTPRFQ 73 Query: 107 SIIQK 111 ++ Sbjct: 74 QLLGD 78 >6EZO-E nrPDB Length = 452 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 49 AVLPAGGCGERMG---VPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGE 100 AV+ A G G RM PK P+ +PLI Y L LERV ++++V T + Sbjct: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVG-FEEVIVVTTRD 58 >4HO3-A nrPDB Length = 297 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 44/106 (41%), Gaps = 15/106 (14%) Query: 50 VLPAGGCGERMGVPTP---KQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ +GG G R+ T KQ P+ ++P++ Y L L IKDI++ T E+ + Sbjct: 4 IILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAG-IKDILIISTPEDTPRFE 62 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVV 152 ++ G S+ +++ + + + E + Sbjct: 63 QLLG-----------GGSELGISLSYAVQSSPDGLAQAFIIGEEFI 97 >5IFY-A nrPDB Length = 305 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ KQ P+ ++P+I Y L L I+D+++ T ++ + Sbjct: 14 IILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAG-IRDVLIISTPQDTPRFE 72 Query: 107 SIIQK 111 S++ Sbjct: 73 SMLGD 77 >1H4E-A nrPDB Length = 201 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 31/185 (16%), Positives = 63/185 (34%), Gaps = 20/185 (10%) Query: 46 AVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVV-------AVT 98 + V+ AGG RMG K + +PL + AL + + +VV Sbjct: 6 TITGVVLAGGKARRMG-GVDKGLLELNGKPLWQHVADAL--MTQLSHVVVNANRHQEIYQ 62 Query: 99 GENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNG-------LKALAEDQINSKLSKPEV 151 ++V++ + Y ++ F + ++N + V Sbjct: 63 ASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCNTPYIPPDLAARLNHQRKDAPV 122 Query: 152 VIIHDAVRPFVEEGVLLKVVT-AAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHRA 210 V +HD R ++ + + E+ AG R +V + + +D+S + Sbjct: 123 VWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMV--FMRLAGGHAVDFSDHKDAFVN 180 Query: 211 SEMPQ 215 P+ Sbjct: 181 VNTPE 185 >1LVW-A nrPDB Length = 295 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ KQ PI ++P+I Y L L I+DI++ T ++ + + Sbjct: 7 IVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAG-IRDILIISTPRDLPLYR 65 Query: 107 SIIQK 111 ++ Sbjct: 66 DLLGD 70 >4D48-A nrPDB Length = 302 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 62/170 (36%), Gaps = 29/170 (17%) Query: 49 AVLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 AV+P G G RM PK+ P++++PLI Y + I +IV+ + Sbjct: 11 AVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAG-INEIVLVTHSSKNSIE 69 Query: 106 KSIIQKYQHKRISLVEAGVTRH-------------------RSIFNGLKALAEDQINSKL 146 ++ + +++E V R + + GL Sbjct: 70 NHFDTSFELE--AMLEKRVKRQLLEEIQSICPPHVTIMQVRQGLAKGLGHAVMCAWPVIG 127 Query: 147 SKPEVVIIHDAV----RPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVS 192 ++P VI+ D + + + L +++ E G + + V+ V + Sbjct: 128 NEPVAVILPDVILDEYESDLSKDNLAEMIRRFDETGHSQIMVEPVADVTA 177 >6N0U-A nrPDB Length = 305 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Query: 50 VLPAGGCGERMGVP---TPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ KQ P+ ++P+I Y L L V I+D+++ T ++ + Sbjct: 14 IILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLM-VAGIRDVLIISTPQDTPRFE 72 Query: 107 SIIQK 111 +++ Sbjct: 73 AMLGD 77 >6B5K-A nrPDB Length = 296 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 38/87 (43%), Gaps = 4/87 (4%) Query: 50 VLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 ++ AGG G R+ + KQ P+ ++P+I Y L L + I+DI + T + Sbjct: 4 IILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLM-MAGIRDIQLITTPHDAPGFH 62 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNG 133 ++ H +++ A + + Sbjct: 63 RLLGDGAHLGVNISYATQDQPDGLAQA 89 >2E3D-A nrPDB Length = 302 Score = 44.7 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 30/70 (42%), Gaps = 4/70 (5%) Query: 49 AVLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 AV+P G G RM PK+ P++++PLI Y + I +IV+ + Sbjct: 11 AVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAG-ITEIVLVTHSSKNSIE 69 Query: 106 KSIIQKYQHK 115 ++ + Sbjct: 70 NHFDTSFELE 79 >4MND-A nrPDB Length = 479 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 45/235 (19%), Positives = 83/235 (35%), Gaps = 21/235 (8%) Query: 45 QAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENME- 103 + + AV+ A G G R+G PK + +I T++ L IV + ++++ Sbjct: 39 KLMKAVILAAGLGTRLG-GVPKPLVRVGGCEIILRTMKLLSPHVSEFIIVASRYADDIDA 97 Query: 104 VMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVE 163 +K Y+ R E G ++ L A + L+ + H + F+E Sbjct: 98 FLKDKGFNYKIVRHDRPEKGNG-----YSLLVAKNHVEDRFILTMGD----HVYSQQFIE 148 Query: 164 EGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYS-LERARHRASEMPQAFLFDVI 222 + V + V A +E DG + + + L D I Sbjct: 149 KAVRGEGVIADREPRFVDIG----EATKIRVEDGRVAKIGKDLREFDCVDTGFFVLDDSI 204 Query: 223 YEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESII 277 +E ++ D + +E ++LA V+G V K D+ A + Sbjct: 205 FEHAEKLRDREEIPLSEIVKLAR----LPVTYVDGELW-MDVDTKEDVRRANRAL 254 >1WVC-A nrPDB Length = 259 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIV 94 AV+ AGG G R+ T PK I +P++ + ++ I+ Sbjct: 5 AVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVHGIKDFII 53 >5B04-E nrPDB Length = 458 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 26/158 (16%) Query: 3 AGPPGSARPAEPGPCLSGQRGADHTASASLQSVAGTEPGRHPQAVAAVLPAGGCGERM-- 60 A P ++ P+ GP +SG R + + LQS+ P AV+ A G G + Sbjct: 7 AALPLASSPSILGP-ISGGR---NRGNIQLQSI--------PIEFQAVVFA-GFGNSLYP 53 Query: 61 ---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSIIQKYQHKRI 117 PK PI +P++ Y L LE + I++ + + + Y+ Sbjct: 54 LTGSDALPKALLPIGNKPMLHYPLYWLEAAGFTSAILICMEEAEAHINAWLRSGYEGHMR 113 Query: 118 SLVEAGV--TRHRSIFNGLKALAEDQINSKLSKPEVVI 153 VEA +S + L+A+ S L K + V Sbjct: 114 IHVEAPTILDDSKSSADALRAV------SHLIKNDFVC 145 >4JD0-A nrPDB Length = 251 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 49 AVLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 A++ A G G+R+ PK F L+ Y + +L + ++ V+ V+ ++ Sbjct: 14 AIVLASGAGKRLRSVTGDVPKVFYRFDGCELVKYPMISLMKNG-VERFVLVVSEGYRDLG 72 Query: 106 KSIIQKYQHKRISL 119 + ++ + I + Sbjct: 73 EKVLNDLGVEGIVV 86 >4ECM-A nrPDB Length = 269 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 11/129 (8%) Query: 43 HPQAVAAVLPAGGCGERMGVP---TPKQFCPILERPLISYTLQALERVCWIKDIVVAVTG 99 A+ ++ AGG G R+ T K P+ P+I + + L + C I DI++ Sbjct: 21 QSNAMKGIILAGGTGSRLYPITKVTNKHLLPVGRYPMIYHAVYKL-KQCDITDIMIITGK 79 Query: 100 ENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGL----KALAEDQINSKLSKPEVVIIH 155 E+M + S + Q +S + I L + D++ L Sbjct: 80 EHMGDVVSFLGSGQEFGVSFTYRVQDKAGGIAQALGLCEDFVGNDRMVVILGDNIF---S 136 Query: 156 DAVRPFVEE 164 D +RP+VEE Sbjct: 137 DDIRPYVEE 145 >3NGW-A nrPDB Length = 208 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 44/252 (17%), Positives = 79/252 (31%), Gaps = 60/252 (23%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 + + GG G R+G+ K + + LI + L+ V + + + Sbjct: 1 MKVAVLVGGVGRRIGME--KTEVMLCGKKLIEWVLEKYSPF----QTVFVCR--DEKQAE 52 Query: 107 SIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGV 166 + +Y+ + I + GV I L+ + + PFV+ V Sbjct: 53 KLSSRYEAEFIWDLHKGVGSIAGIHAALRHFGSCVVAAIDM------------PFVKPEV 100 Query: 167 LLKVVTAAKEHGAAGAI------RPLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFD 220 L + ++ G I PL++ +AD L+ R +P + Sbjct: 101 LEHLYKEGEKAGCDALIPKHDYPEPLLAYYAESAADELERAILQ--GIRKILVP-LERLN 157 Query: 221 VIYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKER 280 V+Y ++ +D E + + DL AE Sbjct: 158 VVYYPVEKLRKFDKEL----------------------ISFFNINTPDDLKRAE------ 189 Query: 281 ISQEICVVMDTE 292 EIC M TE Sbjct: 190 ---EICSKMSTE 198 >5I1F-A nrPDB Length = 302 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 5/94 (5%) Query: 45 QAVAAVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGEN 101 + AV P G G R T PK+ P++++PLI Y ++ + I V TG + Sbjct: 11 KVTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIEAGITEMIFV--TGRS 68 Query: 102 MEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLK 135 ++ K L G + S+ +K Sbjct: 69 KRAIEDHFDKSYEIEAELEARGKEKLLSLVRSIK 102 >2E8B-A nrPDB Length = 201 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 58/156 (37%), Gaps = 23/156 (14%) Query: 51 LPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDI-VVAVTGENMEVMKSII 109 + AGG +R G K I + +I + K++ +VA E + + + Sbjct: 19 VLAGGKSKRFGED--KLLYEIKGKKVIERVYET--AKSVFKEVYIVAKDREKFSFLNAPV 74 Query: 110 QKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLLK 169 + + + + ++ LK E+ + V+ D P +++ +L Sbjct: 75 VLDEFEESASIIG-------LYTALKHAKEENV--------FVLSGDL--PLMKKETVLY 117 Query: 170 VVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLER 205 V+ KE + A + T+V + L+ ER Sbjct: 118 VLENFKE-PVSVAKTEKLHTLVGVYSKKLLEKIEER 152 >6I7T-I nrPDB Length = 578 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 61 GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSIIQKY 112 PK PI RP+I Y L K+I V + +E+++S + + Sbjct: 61 STRLPKALLPIGNRPMIEYVLD-WCDQADFKEISVVAPVDEIELIESGLTSF 111 >2UX8-A nrPDB Length = 297 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 59/173 (34%), Gaps = 12/173 (6%) Query: 49 AVLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 AV P G G R PK+ P+++RPLI Y + E V + ++ VTG + Sbjct: 17 AVFPVAGLGTRFLPATKAMPKEMLPVVDRPLIQYAVD--EAVEAGIEQMIFVTGRGKSAL 74 Query: 106 KSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDA--VRPFVE 163 + ++ G + + +G + L I + + + H R V Sbjct: 75 EDHFDIAYELEATMAARG--KSLDVLDGTR-LKPGNIAYVRQQEPMGLGHAVWCARDIVG 131 Query: 164 EGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSL--ERARHRASEMP 214 + ++ G G ++ +V + + ++ P Sbjct: 132 DEPFAVLLPDDFMFGQPGCLKQMVDAYNKVGGNLICAEEVPDDQTHRYGIITP 184 >5J49-A nrPDB Length = 301 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 5/94 (5%) Query: 45 QAVAAVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGEN 101 + AV P G G R T PK+ PI+++PLI Y ++ + I V TG + Sbjct: 11 KVTKAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAMAAGITEMIFV--TGRS 68 Query: 102 MEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLK 135 ++ K L G + + +K Sbjct: 69 KRAIEDHFDKSYEIEAELQARGKDKLLELVRSIK 102 >3JUK-A nrPDB Length = 281 Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 10/93 (10%) Query: 50 VLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMK 106 + PA G G R PK+ PI+++PLI Y ++ E + +++ VTG N ++ Sbjct: 6 LFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVE--EAMEAGCEVMAIVTGRNKRSLE 63 Query: 107 SIIQKYQHKRISLVEAGVTRHR---SIFNGLKA 136 + G + SI N ++ Sbjct: 64 DYFDTSYEIEHQIQ--GTNKENALKSIRNIIEK 94 >5XHW-A nrPDB Length = 237 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 33/66 (50%), Gaps = 4/66 (6%) Query: 49 AVLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 105 V+ AGG G R+ PK I +P + ++ LE ++ I+++++ + ++ Sbjct: 16 VVILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLEDQG-VQRIILSLSYKADYII 74 Query: 106 KSIIQK 111 S+I+ Sbjct: 75 DSLIKD 80 >5VE7-A nrPDB Length = 302 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 3/50 (6%) Query: 49 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVV 95 AV P G G R T PK+ P++++PLI Y ++ + I V Sbjct: 15 AVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFV 64 >4BQH-A nrPDB Length = 549 Score = 36.2 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 43 HPQAVAAVLPAGGCGERMGVPTPKQFCPILE 73 +A ++ AGG G R+G PK F Sbjct: 110 QKGQIAFLILAGGSGTRLGFDKPKGFFTCDG 140 >6JLY-I nrPDB Length = 678 Score = 35.9 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 34/230 (14%), Positives = 71/230 (30%), Gaps = 39/230 (16%) Query: 46 AVAAVLPAGGCGERMGV---PTPKQFCPILERPLISYTLQALERVCWIKDIVVAV---TG 99 A+ A++ + R P+ P+ PLI YT + + ++++ V G Sbjct: 17 ALQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFE-FLALAGVQEVYVFCCAHAG 75 Query: 100 ENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVR 159 + E ++ S+ S+ + L+ L Q L + +++ V Sbjct: 76 QIREYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQ----LITSDFILVSGDVV 131 Query: 160 PFVEEGVLLKVVTAAKEHGAAGAIRPLVST-----------------VVSPSADGCLDYS 202 V +LK +E + +V + ++ + Sbjct: 132 SNVPLNEVLKEHRKRREDDKNAIMTMVVREASPFHRTRARTESSVFVIDKKTSQCVHYQA 191 Query: 203 LERARHRASEMPQAFLFDVIYEAYQQCSDYDLEFGTECLQLALKYCCTKA 252 ER +H S P+ F +LE + + + C Sbjct: 192 NERGKHYVSMDPEIFN-----------EHEELEVRNDLIDCQIDICSNDV 230 >4BMA-A nrPDB Length = 509 Score = 34.7 bits (78), Expect = 0.091, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 49/138 (35%), Gaps = 31/138 (22%) Query: 32 LQSVAGTEPGRHPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIK 91 L+ VAG + VA VL AGG G R+G PK + Sbjct: 121 LKLVAGNK-------VAVVLMAGGQGTRLGSSAPK---------------GCFDIGLPSH 158 Query: 92 DIVVAVTGENMEVMKSIIQKYQHKRISL----VEAGVTRHRSIFNGLKALAEDQINSKLS 147 + + E + ++ + Q+ K + + +G TR + + E L+ Sbjct: 159 KSLFQIQAERIAKLQLLAQRISGKEAVIPWYVMTSGPTRKPT-----EEFFEQHKYFGLN 213 Query: 148 KPEVVIIHDAVRPFVEEG 165 K +V+I V P + Sbjct: 214 KSDVIIFEQGVLPCISNE 231 >2WJF-A nrPDB Length = 247 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 384 PSQKM-ENLMQIREFAKEVKERNILLYGLLISYPQD 418 P +K+ EN +Q+RE AKEV ++ YG I Y D Sbjct: 55 PEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPD 90 >3R2W-A nrPDB Length = 528 Score = 33.5 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 51/139 (36%), Gaps = 8/139 (5%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPILERP----LISYTLQALERVCWIKDIVVAVTGENM 102 + V GG G MG PK + L ++ L + +V + N Sbjct: 128 LVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNT 187 Query: 103 EVM-KSIIQKYQHKRISLVEAGVTRHRSIF--NGLKALAEDQINSKLSKPEVVIIH-DAV 158 + K I+QKY H R+ + +R+ I + L + + + ++ H D Sbjct: 188 DEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIY 247 Query: 159 RPFVEEGVLLKVVTAAKEH 177 F G+L + KE+ Sbjct: 248 ASFYNSGLLDTFIGEGKEY 266 >1VM8-A nrPDB Length = 534 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPIL 72 VA +L AGG G R+GV PK + Sbjct: 115 VAVLLLAGGQGTRLGVSYPKGMYDVG 140 >1JV1-A nrPDB Length = 505 Score = 33.2 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPIL---ERPLISYTLQALERVCWIKD 92 VA +L AGG G R+GV PK + + L + + ++ + + Sbjct: 103 VAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAE 151 >2I5K-A nrPDB Length = 488 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 34/91 (37%), Gaps = 5/91 (5%) Query: 47 VAAVLPAGGCGERMGVPTPKQFCPI-LERPLI---SYTLQALERVCWIKDIVVAVTGENM 102 +A + GG G MG PK + + ++ L R ++ + N Sbjct: 93 LAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNT 152 Query: 103 EVM-KSIIQKYQHKRISLVEAGVTRHRSIFN 132 + + +I+KY RI + +R ++ Sbjct: 153 DKDTEHLIKKYSANRIRIRSFNQSRFPRVYK 183 >2YQJ-A nrPDB Length = 486 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 45 QAVAAVLPAGGCGERMGVPTPK 66 VA +L AGG G R+G PK Sbjct: 102 GEVAVLLMAGGQGTRLGSSAPK 123 >6HIV-DL nrPDB Length = 307 Score = 32.8 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 40/242 (16%), Positives = 81/242 (33%), Gaps = 41/242 (16%) Query: 32 LQSVAGTEPGRHPQAVAAVLPAGGCGERMGVPTPKQF------CPILER------PLISY 79 ++S T+P + Q A +GG R PK + R L+ + Sbjct: 34 IKSAFTTDPLKEKQK--ARFSSGGEAMREVQDIPKNLEGERSRRDLASRGDTEFQALVEF 91 Query: 80 ----TLQALERVCWIKDIVVAVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLK 135 + L K + ++ + + H +S++ G R R I+N L+ Sbjct: 92 IEGASYDQLISGRRFKKVYDVLSEND-----DMFIWLCHTAMSVLNPGDMRSRLIYNHLR 146 Query: 136 ALAEDQINSKLSK-PEVVIIHDAVRPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPS 194 LAE + ++++ AVR + + + AG + V+ Sbjct: 147 ILAESVASGEMTQRTAFRFFESAVRSPAYREIAKRQLEGGAATRLAGI--SAAADVMRRM 204 Query: 195 A---------DGCLDYSLERARHRASEMPQAFLFDVIYEAYQQCSDY-DLEFGTECLQLA 244 +ER+ + P F +++ ++ S L+F + Q + Sbjct: 205 GLTRRPMSSYFELYQRIVERS---EAMTPWGFPP--LFQFEERLSLEPRLKFFSRASQQS 259 Query: 245 LK 246 L+ Sbjct: 260 LE 261 >6CKJ-A nrPDB Length = 228 Score = 31.2 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 38/243 (15%), Positives = 75/243 (30%), Gaps = 34/243 (13%) Query: 49 AVLPAGGCGERMGVPTP-KQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKS 107 AV+ A + P K + L+ +T+ A I+V+ G + Sbjct: 7 AVILARQNSK----GLPLKNLRKMNGISLLGHTINAAISSKCFDRIIVSTDGGLIAEEAK 62 Query: 108 IIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVL 167 + E SI + AL NS V + P + Sbjct: 63 NFGV--EVVLRPAELASDTASSISGVIHALETIGSNSGT-----VTLLQPTSPLRTGAHI 115 Query: 168 LKVVTAAKE--HGAAGAIRP----LVSTVVSPSADGC--LDYSLERARHRASEMPQAFLF 219 + + E G+ + P + T++ + + + + + R ++PQAF Sbjct: 116 REAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSDLEQPRQ-QLPQAFRP 174 Query: 220 DVIYEAYQQCSDYDLEFGTECLQLALK-YCCTKAKL-VEGSPDLWKVTYKRDLYAAESII 277 + + +A + KL + D + + DL AE+I+ Sbjct: 175 -----------NGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQAENIL 223 Query: 278 KER 280 + Sbjct: 224 NHK 226 >3RHO-A nrPDB Length = 517 Score = 31.2 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 29/82 (35%), Gaps = 13/82 (15%) Query: 1 MEAGPPGSARPAEPGP-CLSGQRGADHTASASLQSVAGTEPGRHPQAVAAVLPAGGCGER 59 ++AG P PG L GQR +DH + TE G+H A+ Sbjct: 229 LKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAL--------- 279 Query: 60 MGVPTPKQFCPILER-PLISYT 80 K + + PLI + Sbjct: 280 --SNVKKVSLQLGGKSPLIIFA 299 >4GIJ-A nrPDB Length = 335 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 26/77 (33%), Gaps = 15/77 (19%) Query: 21 QRGADHT--ASASLQSVAGTEPGRHPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLIS 78 RGA+HT SA LQ +A T + G + + ++ PLI Sbjct: 160 HRGAEHTFDISADLQELANTN---------VTVVCAGAKSILDLGLTTEYLETFGVPLIG 210 Query: 79 YTLQA----LERVCWIK 91 Y +A R Sbjct: 211 YQTKALPAFFCRTSPFD 227 >1Q3S-A nrPDB Length = 548 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 32/69 (46%), Gaps = 8/69 (11%) Query: 260 DLWKVTYKRDLYAAESIIKERISQEICVVMDTEEDNKHVG--------HLLEEVLKSELN 311 K DL AE + + +++ E + ++ ++ K V H+++EV ++ + Sbjct: 334 TNVKDLTPEDLGYAEVVEERKLAGENMIFVEGCKNPKAVTILIRGGTEHVIDEVERALED 393 Query: 312 HVKVTSEAL 320 VKV + + Sbjct: 394 AVKVVKDVM 402 >5OMS-A nrPDB Length = 409 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 30/216 (13%), Positives = 62/216 (28%), Gaps = 34/216 (15%) Query: 30 ASLQSVAGTEPGRHPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCW 89 A L V T+ R+P V ER+ P F P+L + Sbjct: 12 AWLDEVTMTQLERNPYEVY---------ERLRAEAPLAFVPVLG--------SYVASTAE 54 Query: 90 IKDIVVAVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKP 149 + V + + + + H I V H + + ++ + + Sbjct: 55 VCREVATSPDFEAVITPAGGRTFGHPAIIGVNG--DIHADLRSMVEPALQPAEVDRWID- 111 Query: 150 EVVIIHDAVRPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTV-VSPSADGCLDYSLERARH 208 D VRP + + + G A + V V D ++ + Sbjct: 112 ------DLVRPIAR-----RYLERFENDGHAELVAQYCEPVSVRSLGDLLGLQEVDSDKL 160 Query: 209 --RASEMPQAFLFDVIYEAYQQCSDYDLEFGTECLQ 242 +++ ++F + E + + G + Sbjct: 161 REWFAKLNRSFTNAAVDENGEFANPEGFAEGDQAKA 196 >6DD5-A nrPDB Length = 678 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 34/94 (36%), Gaps = 12/94 (12%) Query: 88 CWIKDIVVAVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSIFNGLKALAEDQINSKLS 147 D +V EN + Y+ RI+++ G + ++F+ LK L E N Sbjct: 420 EQFSDFIVVEPIENGHISYQAGDGYRF-RITVLNGGESLLDTLFSSLKRLPESAANHP-- 476 Query: 148 KPEVVIIHDAVRPFVEEGVLLKVVTAAKEHGAAG 181 D F + ++L+ + EH Sbjct: 477 --------DIAGAF-SDNLVLEKIEDTFEHHQVT 501 >2QSJ-A nrPDB Length = 154 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 35/89 (39%), Gaps = 4/89 (4%) Query: 69 CPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSI--IQKYQHKRISLVEAGVTR 126 + +S L LE + I++ V + E + + ++++ + +G T Sbjct: 30 MRVEGAETVSDALAFLEADNTVDLILLDVNLPDAEAIDGLVRLKRFDPSNAVALISGETD 89 Query: 127 HRSIFNGLKALAEDQINSKLSKPEVVIIH 155 H I L+A A+ I V+IH Sbjct: 90 HELIRAALEAGADGFIPKSADPQ--VLIH 116 >5IEF-A nrPDB Length = 913 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 37/115 (32%), Gaps = 16/115 (13%) Query: 126 RHRSIFNGLKALAEDQINSKLSKPEVV--IIHDAVRPFVEEGV-----------LLKVVT 172 R RSI GL +L + +IH+ + + + + ++ Sbjct: 17 RQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEP 76 Query: 173 AAKEHGAAGAIR---PLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYE 224 + + P VS D ++ ++ ++ Q F D++ + Sbjct: 77 RRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLED 131 >5HJR-A nrPDB Length = 857 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 37/115 (32%), Gaps = 16/115 (13%) Query: 126 RHRSIFNGLKALAEDQINSKLSKPEVV--IIHDAVRPFVEEGV-----------LLKVVT 172 R RSI GL +L + +IH+ + + + + ++ Sbjct: 17 RQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEP 76 Query: 173 AAKEHGAAGAIR---PLVSTVVSPSADGCLDYSLERARHRASEMPQAFLFDVIYE 224 + + P VS D ++ ++ ++ Q F D++ + Sbjct: 77 RRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLED 131 >3DR5-A nrPDB Length = 221 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 60/187 (32%), Gaps = 30/187 (16%) Query: 20 GQRGADHTASASLQSVAGTEPGRHPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISY 79 G D L ++A T G A+ PA G + Y Sbjct: 33 GLPAPDEMTGQLLTTLAATTNGNGSTGAIAITPAAGL-------------------VGLY 73 Query: 80 TLQALERVCWIKDIVVAVTGENMEV--MKSIIQK--YQHKRISLVEAGVTRHRSIFNGLK 135 L L + + E+ K++ ++ Y R+ + ++R + + L Sbjct: 74 ILNGLADNT----TLTCIDPESEHQRQAKALFREAGYSPSRVRFL---LSRPLDVMSRLA 126 Query: 136 ALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSA 195 + + ++S ++ + DA P + G L + A + A R T + A Sbjct: 127 NDSYQLVFGQVSPMDLKALVDAAWPLLRRGGALVLADALLDGTIADQTRKDRDTQAARDA 186 Query: 196 DGCLDYS 202 D + Sbjct: 187 DEYIRSI 193 >3H4P-a nrPDB Length = 219 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 51/152 (33%), Gaps = 25/152 (16%) Query: 43 HPQAVAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVA------ 96 QA+ +L A +M P+ L+S L + ++ I++ Sbjct: 52 DAQAIVRLLIAEAKLYKMRTGRNIP--PLACATLLSNILHSSRMFPFLTQIIIGGYDLLE 109 Query: 97 -------VTGENMEVMKSIIQKYQHKRIS--LVEAGVTRHRSI-------FNGLKALAED 140 M K+ I+ ++EAG R S+ N LK+ E Sbjct: 110 GAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMER 169 Query: 141 QINSKLSKPEVVIIHDAVRPFVEEGVLLKVVT 172 S VI D V+ F E+ + K++ Sbjct: 170 DTFSGNGISLAVITKDGVKIF-EDEEIEKILD 200 >6MSK-X nrPDB Length = 422 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 17/103 (16%) Query: 347 DFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVKERNI 406 +FQ Q LLS E+S+ IL+ +V ++ + E A +VKE++I Sbjct: 8 EFQRAQSLLSTDREASIDILHSIV-----------------KRDIQENDEEAVQVKEQSI 50 Query: 407 LLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLL 449 L G L++ +L L+ + S+ K + + L+ LL Sbjct: 51 LELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLL 93 >2PA4-A nrPDB Length = 323 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 16/33 (48%), Gaps = 3/33 (9%) Query: 49 AVLPAGGCGERMGVP---TPKQFCPILERPLIS 78 V+PA G G R PK+ P+++ P I Sbjct: 15 VVVPAAGLGTRFLPATKTVPKELLPVVDTPGIE 47 >5W6J-A nrPDB Length = 420 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 46/130 (35%), Gaps = 15/130 (11%) Query: 44 PQAVAAVLPAGGCGERMGV---PTPKQFCPILERP-LISYTLQALERVCWIKDIVVAVTG 99 + A + AGG G R+ K + +I + L I+ I VA Sbjct: 10 ARDAMAYVLAGGRGSRLKELTDRRAKPAVYFGGKARIIDFALSN-ALNSGIRRIGVATQY 68 Query: 100 ENMEVMKSIIQKYQHKRISLVEAGVTRHRS--IFNGLKALAEDQINSKLSKPEVVIIHDA 157 + +++ + + + R R+ S I + ++E Q + I D Sbjct: 69 KAHSLIRHLQRGWDFFR-------PERNESFDILPASQRVSETQWYEGTADAVYQNI-DI 120 Query: 158 VRPFVEEGVL 167 + P+ E ++ Sbjct: 121 IEPYAPEYMV 130 >3OC9-A nrPDB Length = 405 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 10/22 (45%), Positives = 12/22 (54%) Query: 45 QAVAAVLPAGGCGERMGVPTPK 66 A + PAGG G R+G PK Sbjct: 34 GKTALITPAGGQGSRLGFEHPK 55 >1B74-A nrPDB Length = 254 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 29/80 (36%), Gaps = 8/80 (10%) Query: 74 RPLISYTLQ--ALERVCWIKDIVVAVTGENMEVMKSIIQKYQHKRISLVEAGVTRHRSIF 131 +I Y+L+ + + IVVA + ++ + ++ ++E G + Sbjct: 45 DTIIRYSLECAGFLKDKGVDIIVVACNTASAYALERLKKEINVPVFGVIEPG------VK 98 Query: 132 NGLKALAEDQINSKLSKPEV 151 LK +I + V Sbjct: 99 EALKKSRNKKIGVIGTPATV 118 >2W3Z-A nrPDB Length = 311 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 23/55 (41%) Query: 124 VTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEGVLLKVVTAAKEHG 178 TR ++ + L L + +VV++HD + L +++ K+ G Sbjct: 250 ATRPTTVASMLAFLDGSAKIATNPNVQVVLMHDISEKTITLASLPQIIRYYKDRG 304 >4FCU-A nrPDB Length = 253 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 44/129 (34%), Gaps = 21/129 (16%) Query: 50 VLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSII 109 V+PA R+ K I +RP+I + ++V D+ VA E + I Sbjct: 5 VIPARFSSSRLPG---KPLLLIHDRPMILRVVDQAKKVEGFDDLCVATDDERIAE----I 57 Query: 110 QKYQHKRISLVEA----GVTRHRSIFNGLKALAEDQINSKLSKPEVVIIHDAVRPFVEEG 165 + + + L A G R L+E ++++ P + Sbjct: 58 CRAEGVDVVLTSADHPSGTDR----------LSEVARIKGWDADDIIVNVQGDEPLLPAQ 107 Query: 166 VLLKVVTAA 174 ++ +V Sbjct: 108 LVQQVAKLL 116 >5Y9S-A nrPDB Length = 304 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 8/86 (9%) Query: 291 TEEDNKHVGHLLEEVLKSELNHVKVTSEALGHAGRHLQQIILDQCYNFVCVNVTTSDFQE 350 TE K V + ++ LN VKVT E A + C + + VN+ F + Sbjct: 66 TEHGQKFVPYA-----ENLLNQVKVTKEDFAQASLKTDHTVRIVCLHTLAVNLLPKLFLQ 120 Query: 351 TQKLLSMLEESSLCILYPVVVVSVHF 376 + + LS L +L + V+ + HF Sbjct: 121 SAEALSHL---NLSVTPSVLGIDAHF 143 >4XCI-A nrPDB Length = 559 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 2/75 (2%) Query: 260 DLWKVTYKRDLYAAESIIKERISQEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVTSEA 319 K DL AE + + R+ + V ++ ++ K V LL L+ + + Sbjct: 339 SSIKDATPEDLGYAELVEERRVGNDKMVFIEGAKNLKAVNILLRGSNDMALDEAERSIND 398 Query: 320 LGHAGRH--LQQIIL 332 HA R+ L+ +IL Sbjct: 399 ALHALRNILLEPVIL 413 >3LK5-A nrPDB Length = 380 Score = 28.9 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 45/155 (29%), Gaps = 42/155 (27%) Query: 158 VRPFVEEGVLL----KVVTAAKEHG-AAGAIRPLVSTVVSPSADGCLDYSLERARHRASE 212 RP + +++ A +G G L ++ D + R + Sbjct: 222 ARPLHLGASIAGGSPQLIDALLHYGHDIGIAFQLRDDLLGVFGDPAITGKPAGDDIREGK 281 Query: 213 MPQAFLFDVIYEAYQQCSDYDLEFGTECLQLALKYCCTKAKLVEGSPDLWKVTYKRDLYA 272 ++ A Q+ E T A++ KVT D+ Sbjct: 282 -----RTVLLALALQRADKQSPEAAT-----AIRAGVG------------KVTSPEDIAV 319 Query: 273 ---------AESIIKERISQEICVVMDTEEDNKHV 298 AE +++RISQ TE H+ Sbjct: 320 ITEHIRATGAEEEVEQRISQL------TESGLAHL 348 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.129 0.342 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,582,268 Number of Sequences: 36641 Number of extensions: 572357 Number of successful extensions: 2060 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 75 Number of HSP's that attempted gapping in prelim test: 1875 Number of HSP's gapped (non-prelim): 144 length of query: 451 length of database: 10,336,785 effective HSP length: 100 effective length of query: 351 effective length of database: 6,672,685 effective search space: 2342112435 effective search space used: 2342112435 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.1 bits)