BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= A0A1L8F5J9 (903 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5UOW-A nrPDB 1661 0.0 5FXI-A nrPDB 1589 0.0 5UN1-G nrPDB 895 0.0 5IPR-B nrPDB 302 4e-82 5I2K-B nrPDB 299 5e-81 4PE5-B nrPDB 298 8e-81 6IRA-D nrPDB 294 9e-80 5UP2-B nrPDB 292 5e-79 5UN1-B nrPDB 268 7e-72 5KUF-A nrPDB 268 1e-71 6QKC-A nrPDB 253 3e-67 4U1Y-A nrPDB 233 3e-61 5IDF-B nrPDB 225 8e-59 5KUH-A nrPDB 124 2e-28 2RC9-A nrPDB 105 6e-23 2RCB-A nrPDB 103 4e-22 5H8N-A nrPDB 101 2e-21 3OEK-A nrPDB 97 2e-20 4IGR-A nrPDB 96 6e-20 2XXT-A nrPDB 95 2e-19 5O9A-A nrPDB 93 5e-19 4MF3-A nrPDB 92 8e-19 1YAE-A nrPDB 91 2e-18 3DP4-A nrPDB 89 6e-18 3FAT-A nrPDB 89 1e-17 5IKB-A nrPDB 87 4e-17 5DT6-A nrPDB 80 3e-15 5EHM-A nrPDB 80 4e-15 5L2E-A nrPDB 69 6e-12 4YKP-A nrPDB 68 2e-11 5CC2-A nrPDB 62 1e-09 5K5S-A nrPDB 62 2e-09 4ZDM-A nrPDB 62 2e-09 5FBH-B nrPDB 61 2e-09 4WXJ-A nrPDB 59 1e-08 5CNI-A nrPDB 52 1e-06 2E4V-A nrPDB 52 1e-06 5CNM-A nrPDB 52 2e-06 5KZQ-A nrPDB 52 2e-06 5X2M-A nrPDB 50 4e-06 6BT5-A nrPDB 49 7e-06 5TUJ-C nrPDB 47 4e-05 5X2N-B nrPDB 45 1e-04 4IO3-A nrPDB 43 5e-04 5C5C-A nrPDB 43 7e-04 4ZV2-A nrPDB 42 8e-04 4F3S-A nrPDB 42 0.001 2Q2A-A nrPDB 41 0.002 1GGG-A nrPDB 41 0.002 1YK0-A nrPDB 40 0.004 2PYY-A nrPDB 40 0.004 4PSH-A nrPDB 40 0.005 5OTA-A nrPDB 39 0.011 6FXG-A nrPDB 39 0.012 4KPT-A nrPDB 39 0.012 4ZEF-A nrPDB 39 0.013 1ISS-A nrPDB 39 0.015 3K4U-A nrPDB 38 0.016 3LMK-A nrPDB 37 0.029 6N4Y-A nrPDB 37 0.031 4F3P-A nrPDB 37 0.045 6N4X-A nrPDB 37 0.051 3I6V-A nrPDB 37 0.056 4YMX-A nrPDB 36 0.081 4G4P-A nrPDB 35 0.12 5JOS-A nrPDB 35 0.19 2IEE-A nrPDB 35 0.19 3VV5-A nrPDB 35 0.21 5EYF-A nrPDB 35 0.22 4H5F-A nrPDB 33 0.50 3OJO-A nrPDB 33 0.79 4F11-A nrPDB 32 0.86 6CCZ-A nrPDB 32 1.8 4I62-A nrPDB 32 1.8 2HOR-A nrPDB 31 1.9 5ORE-A nrPDB 31 2.9 3TQL-A nrPDB 30 3.8 4CHV-A nrPDB 30 4.2 3KTD-A nrPDB 30 5.1 5A1S-A nrPDB 29 8.7 4CBI-A nrPDB 29 8.9 >5UOW-A nrPDB Length = 814 Score = 1661 bits (4301), Expect = 0.0, Method: Compositional matrix adjust. Identities = 796/814 (97%), Positives = 800/814 (98%) Query: 23 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 82 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL Sbjct: 1 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 60 Query: 83 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 142 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP Sbjct: 61 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 120 Query: 143 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK 202 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK Sbjct: 121 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK 180 Query: 203 NLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYA 262 NLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYA Sbjct: 181 NLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYA 240 Query: 263 PDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFK 322 PDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEME ITDPPRGCVGNTNIWKTGPLFK Sbjct: 241 PDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMEQITDPPRGCVGNTNIWKTGPLFK 300 Query: 323 RVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWP 382 RVLMSSKYPDGVTGRIEFNEDGDRKFA YSIMNLQNRKLVQVGIF+GSYIIQNDRKIIWP Sbjct: 301 RVLMSSKYPDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWP 360 Query: 383 GGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNET 442 GGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGP+ET Sbjct: 361 GGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDET 420 Query: 443 IPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGE 502 IPGRPTVPQCCYGFCVDLLIKLAREM+FTYEVHLVADGKFGTQERVNNSN WNGMMGE Sbjct: 421 IPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGE 480 Query: 503 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWL 562 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWL Sbjct: 481 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWL 540 Query: 563 LVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAP 622 LVGLSVHVVAVMLYLLDRFSPFGRFKVNS EEDALTLSSAMWFSW VLLNSG+GEGAP Sbjct: 541 LVGLSVHVVAVMLYLLDRFSPFGRFKVNSAAAEEDALTLSSAMWFSWRVLLNSGLGEGAP 600 Query: 623 RSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATV 682 RSFSARILGMVWA FAMIIVASYTANLAAFLVL RPEERITGINDPRLRNPSDKFIYATV Sbjct: 601 RSFSARILGMVWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATV 660 Query: 683 KQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKC 742 KQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQ C Sbjct: 661 KQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQDC 720 Query: 743 DLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSNA 802 DLVTTGELFFRSGFGIGMRKDSPWKQ VSLNILKSHENGFMEELDKTWVRYQECDSRSNA Sbjct: 721 DLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNA 780 Query: 803 PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYK 836 PATLTFENMAGVF LVAGGIVAGIFLIFIEIAYK Sbjct: 781 PATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814 >5FXI-A nrPDB Length = 846 Score = 1589 bits (4115), Expect = 0.0, Method: Compositional matrix adjust. Identities = 753/846 (89%), Positives = 793/846 (93%), Gaps = 23/846 (2%) Query: 23 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 82 DPKIVNIGAVLST+KHEQ+FREAVNQANKRH + KIQL ATSVTH+PNAIQMALSVCEDL Sbjct: 1 DPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLQATSVTHKPNAIQMALSVCEDL 60 Query: 83 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 142 ISSQVYAILVSHPP P DH TPTP+SYTAGFYRIPV+GLTTRMSIYSDKSIHLSFLRTVP Sbjct: 61 ISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVP 120 Query: 143 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESK------------ 190 PYSHQ+ VWFEMMR++NWNH+IL+VSDDHEGRAAQK+LETLLEE+ESK Sbjct: 121 PYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKSKKRNYENLDQL 180 Query: 191 ---------ADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMT 241 A+KVLQF+PGTKN+TALL+EA+ELEARVIILSASEDDA VY++AAMLDMT Sbjct: 181 SYDNKRGPKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLDMT 240 Query: 242 GAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENI 301 G+GYVWLVGEREISG+ALRYAPDGIIGLQLINGKNESAHISDAV VVAQA+HEL E ENI Sbjct: 241 GSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENI 300 Query: 302 TDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKL 361 TDPPRGCVGNTNIWKTGPLFKRVLMSSKY DGVTGR+EFNEDGDRKFA YSIMNLQNRKL Sbjct: 301 TDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKL 360 Query: 362 VQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCR 421 VQVGI+NG+++I NDRKIIWPGGETE+P+GYQMSTRLKIVTIHQEPFVYV+PT SDGTC+ Sbjct: 361 VQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCK 420 Query: 422 EEYTINGDPIKKVICNGPNETIPGRP--TVPQCCYGFCVDLLIKLAREMNFTYEVHLVAD 479 EE+T+NGDP+KKVIC GPN+T PG P TVPQCCYGFC+DLLIKLAR M FTYEVHLVAD Sbjct: 421 EEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMQFTYEVHLVAD 480 Query: 480 GKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL 539 GKFGTQERV NSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL Sbjct: 481 GKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL 540 Query: 540 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDAL 599 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNS+ E DAL Sbjct: 541 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSQSESTDAL 600 Query: 600 TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPE 659 TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPE Sbjct: 601 TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPE 660 Query: 660 ERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAV 719 ERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAV Sbjct: 661 ERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAV 720 Query: 720 RDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHE 779 RDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQ VSL+ILKSHE Sbjct: 721 RDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHE 780 Query: 780 NGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 839 NGFME+LDKTWVRYQECDSRSNAPATLT ENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK Sbjct: 781 NGFMEDLDKTWVRYQECDSRSNAPATLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 840 Query: 840 DARRKQ 845 DA Q Sbjct: 841 DANGAQ 846 >5UN1-G nrPDB Length = 451 Score = 895 bits (2313), Expect = 0.0, Method: Compositional matrix adjust. Identities = 430/458 (93%), Positives = 438/458 (95%), Gaps = 9/458 (1%) Query: 394 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCC 453 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGP+ETIPGRPTVPQCC Sbjct: 1 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCC 60 Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 YGFCVDLLIKLAREM+FTYEVHLVADGKFGTQERVNNSN WNGMMGELLSGQADMIVA Sbjct: 61 YGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVA 120 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 573 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV Sbjct: 121 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 180 Query: 574 MLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMV 633 MLYLLDRFSPFGRF EDALTLSSAMWFSW VLLNSG+GEGAPRSFSARILGMV Sbjct: 181 MLYLLDRFSPFGRF--------EDALTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMV 232 Query: 634 WAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR 693 WAGFAMIIVASYTANLAAFLVL RPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR Sbjct: 233 WAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR 292 Query: 694 QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR 753 QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR Sbjct: 293 QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR 352 Query: 754 SGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAG 813 SGFGIGMRKDSPWKQ VSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAG Sbjct: 353 SGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAG 412 Query: 814 VFMLVAGGIVAGIFLIFIEIAYKRHKDARR-KQMQLAF 850 VFMLVAGGIVAGIFLIFIEIAYK +A+R K +++ F Sbjct: 413 VFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMKGLEVLF 450 >5IPR-B nrPDB Length = 825 Score = 302 bits (774), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 215/743 (28%), Positives = 386/743 (51%), Gaps = 64/743 (8%) Query: 117 PVIGLTTRMS-IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG-R 174 P++G+ S I +DK F + P QA V +M ++W ++ IV+ G + Sbjct: 117 PILGIHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDW-YIFSIVTTYFPGYQ 175 Query: 175 AAQKKLETLLEEKES--KADKVLQFEPGTKNLTALLL-EAKELEARVIILSASEDDATAV 231 + K+ + +E + ++V+ + ++ + + + K+L++ VI+L ++++AT + Sbjct: 176 DFENKVRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYI 235 Query: 232 YKSAAMLDMTGAGYVWLV-----GEREISGSALRYAPDGIIGLQLINGKNE-SAHISDAV 285 ++ A + +TG G+ W+V G+ + P G+I + + A + D + Sbjct: 236 FEVAHSVGLTGYGFTWIVPSLVAGDTDTVPDEF---PTGLISVSYDEWDYDLPARVRDGI 292 Query: 286 AVVAQAIHELFEMENITDPPRGCVGNTNIWKT--GPLFKRVLMSSKYPDGVTGR-IEFNE 342 A++ A + N + N + + KR L++ + GR + F+E Sbjct: 293 AIITTAASTMLSEHNSIPQSKSSCNNIQESRVYEAHMLKRYLINVTF----EGRDLSFSE 348 Query: 343 DGDRKFANYSIMNL-QNRKLVQVGIFNGSYIIQNDRKI-IWPGGETERPQGYQMSTRLKI 400 DG + I+ L Q RK +VG + DR + +WP + L I Sbjct: 349 DGYQMHPKLVIILLNQERKWERVGKYK-------DRSLKMWPVFDLYPNSEEHKDEHLSI 401 Query: 401 VTIHQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVD 459 VT+ + PFV V GTC N P +K I N T G + +CC GFC+D Sbjct: 402 VTLEEAPFVIVEDVDPLSGTCMR----NTVPCRKQI-RPENRTEEGGNYIKRCCKGFCID 456 Query: 460 LLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINN 519 +L K+A+ + FTY+++LV +GK G +++N WNGM+GE+++ +A M V LTIN Sbjct: 457 ILKKIAKTVKFTYDLYLVTNGKHG--KKINGV----WNGMIGEVVTKRAYMAVGSLTINE 510 Query: 520 ERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVMLYLL 578 ER++ ++FS PF G++++V + + +F++PF + +W+++ + + +V AV +++ Sbjct: 511 ERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVF 570 Query: 579 DRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFA 638 + FSP G + T+ A+W WG++ N+ + P+ +++I+ VWA FA Sbjct: 571 EYFSPVGY--------NGPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFA 622 Query: 639 MIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQV 695 +I +ASYTANLAAF++ R ++++G++D + + P+D F + TV S + R Sbjct: 623 VIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNN- 681 Query: 696 ELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEA--SQKCDLVT--TGELF 751 M+ +M K N S +A+ +++ KL AFI+D+AVL + A + C LVT +G++F Sbjct: 682 -YLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVF 740 Query: 752 FRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFE 809 +G+GI ++KDS WK+ V L IL+ +G MEEL+ W+ C + N + L + Sbjct: 741 ATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLT-GICHNEKNEVMSSQLDID 799 Query: 810 NMAGVFMLVAGGIVAGIFLIFIE 832 NMAGVF ++A + + +E Sbjct: 800 NMAGVFYMLAAAMALSLITFIME 822 >5I2K-B nrPDB Length = 293 Score = 299 bits (765), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 137/151 (90%), Positives = 144/151 (95%), Gaps = 2/151 (1%) Query: 394 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRP--TVPQ 451 MSTRLKIVTIHQEPFVYV+PT SDGTC+EE+T+NGDP+KKVIC GPN+T PG P TVPQ Sbjct: 3 MSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQ 62 Query: 452 CCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMI 511 CCYGFC+DLLIKLAR MNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMI Sbjct: 63 CCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMI 122 Query: 512 VAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 VAPLTINNERAQYIEFSKPFKYQGLTILVKK Sbjct: 123 VAPLTINNERAQYIEFSKPFKYQGLTILVKK 153 Score = 296 bits (758), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 146/184 (79%), Positives = 157/184 (85%), Gaps = 14/184 (7%) Query: 629 ILGMVWAGFAMIIVASYTAN--LAAFLVLDRPEE------------RITGINDPRLRNPS 674 ++G + +G A +IVA T N A ++ +P + RITGINDPRLRNPS Sbjct: 110 MMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPS 169 Query: 675 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL 734 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL Sbjct: 170 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL 229 Query: 735 EFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQ 794 EFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSL+ILKSHENGFME+LDKTWVRYQ Sbjct: 230 EFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQ 289 Query: 795 ECDS 798 ECDS Sbjct: 290 ECDS 293 >4PE5-B nrPDB Length = 820 Score = 298 bits (762), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 232/849 (27%), Positives = 429/849 (50%), Gaps = 80/849 (9%) Query: 19 RAGCDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFT--RKIQLNATSVTHRPNAIQMAL 76 R+ P + I +L E ++A + + H + +++L A + T + I Sbjct: 1 RSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIIT--- 57 Query: 77 SVCEDLISSQVYAILVSHPPAPTDHLTPTPI-SYTAGFYRIPVIGLTTRMS-IYSDKSIH 134 +C+ + ++ ++ + TD I + + P++G+ S I +DK Sbjct: 58 RICDLMSDRKIQGVVFADD---TDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDES 114 Query: 135 LSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG-RAAQKKLETLLE------EK 187 F + P QA V +M ++W ++ IV+ G + K+ + +E E Sbjct: 115 SMFFQFGPSIEQQASVMLNIMEEYDW-YIFSIVTTYFPGYQDFVNKIRSTIENSFVGWEL 173 Query: 188 ESKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVW 247 E + + G + L K+L++ +I+L ++++AT +++ A + +TG GY W Sbjct: 174 EEVLLLDMSLDDGDCKIQNQL---KKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTW 230 Query: 248 LV-----GEREISGSALRYAPDGIIGLQLIN-GKNESAHISDAVAVVAQAIHELFEMENI 301 +V G+ + S P G+I + A + D +A++ A ++ + Sbjct: 231 IVPSLVAGDTDTVPSEF---PTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSF 287 Query: 302 TDPPRGCVGNTN---IWKTGPLFKRVLMSSKYPDGVTGR-IEFNEDGDRKFANYSIMNL- 356 P+ NT+ I+++ + R L++ + GR + F+EDG + I+ L Sbjct: 288 IPEPKSSCYNTHEKRIYQSN-MLNRYLINVTF----EGRDLSFSEDGYQMHPKLVIILLN 342 Query: 357 QNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTS 416 + RK +VG + + + +WP + L IVT+ + PFV V Sbjct: 343 KERKWERVGKWKDKSL--QMKYYVWPRMTQD--------DHLSIVTLEEAPFVIVESVDP 392 Query: 417 -DGTCREEYTINGDPI-KKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEV 474 GTC N P K++I + PG + +CC GFC+D+L K+++ + FTY++ Sbjct: 393 LSGTCMR----NTVPCQKRIISENKTDEEPGY--IKKCCKGFCIDILKKISKSVKFTYDL 446 Query: 475 HLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQ 534 +LV +GK G +++N + WNGM+GE++ +A M V LTIN ER++ ++FS PF Sbjct: 447 YLVTNGKHG--KKINGT----WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIET 500 Query: 535 GLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVMLYLLDRFSPFG--RFKVNS 591 G++++V + + +F++PF + +W+++ + + +V AV +++ + FSP G R + Sbjct: 501 GISVMVSRSNGTVSPSAFLEPFSACVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRSLADG 560 Query: 592 EEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAA 651 E + T+ A+W WG++ N+ + P+ +++I+ VWA FA+I +ASYTANLAA Sbjct: 561 REPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAA 620 Query: 652 FLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVELSTMYRHMEKHN 708 F++ + ++++G++D + + P+D F + TV S + R + M+ +M K N Sbjct: 621 FMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN--YAEMHAYMGKFN 678 Query: 709 YESAAEAIQAVRDNKLHAFIWDSAVLEFEA--SQKCDLVT--TGELFFRSGFGIGMRKDS 764 +A+ +++ KL AFI+D+AVL + A + C LVT +G++F +G+GI ++KDS Sbjct: 679 QRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDS 738 Query: 765 PWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFENMAGVFMLVAGGI 822 WK+ V L IL+ +G MEEL+ W+ C + N + L +NMAGVF ++ G Sbjct: 739 GWKRQVDLAILQLFGDGEMEELEALWLT-GICHNEKNEVMSSQLDCDNMAGVFYML-GAA 796 Query: 823 VAGIFLIFI 831 +A + FI Sbjct: 797 MALSLITFI 805 >6IRA-D nrPDB Length = 853 Score = 294 bits (753), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 221/761 (29%), Positives = 392/761 (51%), Gaps = 61/761 (8%) Query: 116 IPVIGLTTRMS-IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG- 173 +P++G+ S I +DK +F + QA V ++M+ ++W HV +V+ G Sbjct: 122 VPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDW-HVFSLVTTIFPGY 180 Query: 174 RAAQKKLETLLEEKESKAD--KVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAV 231 R ++T ++ D V+ + ++ ++ K++ + VI+L S+D+A + Sbjct: 181 REFISFVKTTVDNSFVGWDMQNVITLDTSFED-AKTQVQLKKIHSSVILLYCSKDEAVLI 239 Query: 232 YKSAAMLDMTGAGYVWLVGEREISGSAL--RYAPDGIIGLQLINGKNE-SAHISDAVAVV 288 A L +TG + W+V + L + P G+I + + A + D + ++ Sbjct: 240 LSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGIGIL 299 Query: 289 AQAIHELFE-MENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRK 347 A + E I + C G + M + DG + F E+G + Sbjct: 300 TTAASSMLEKFSYIPEAKASCYGQMERPEVPMHTLHPFMVNVTWDG--KDLSFTEEGYQV 357 Query: 348 FANYSIMNL-QNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMS----TRLKIVT 402 ++ L ++R+ +VG + + + R +WP R + + L IVT Sbjct: 358 HPRLVVIVLNKDREWEKVGKWENHTL--SLRHAVWP-----RYKSFSDCEPDDNHLSIVT 410 Query: 403 IHQEPFVYVR---PTTSDGTCREEYTINGDPIKKV--ICNGPNETIPGRPTVPQCCYGFC 457 + + PFV V P T TC N P +K I N NE + V +CC GFC Sbjct: 411 LEEAPFVIVEDIDPLTE--TCVR----NTVPCRKFVKINNSTNEGM----NVKKCCKGFC 460 Query: 458 VDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTI 517 +D+L KL+R + FTY+++LV +GK G ++VNN WNGM+GE++ +A M V LTI Sbjct: 461 IDILKKLSRTVKFTYDLYLVTNGKHG--KKVNNV----WNGMIGEVVYQRAVMAVGSLTI 514 Query: 518 NNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVMLY 576 N ER++ ++FS PF G++++V + + +F++PF +++W+++ + + +V A+ ++ Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVF 574 Query: 577 LLDRFSPFG--RFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVW 634 + + FSP G R + + T+ A+W WG++ N+ + P+ +++I+ VW Sbjct: 575 VFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVW 634 Query: 635 AGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYF 691 A FA+I +ASYTANLAAF++ R +++TG++D + + P D F + TV S + Sbjct: 635 AFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNI 694 Query: 692 RRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEAS--QKCDLVT--T 747 R M+++M K N + +A+ +++ KL AFI+D+AVL ++A + C LVT + Sbjct: 695 RNNYPY--MHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGS 752 Query: 748 GELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APAT 805 G +F +G+GI ++K SPWK+ + L +L+ +G MEEL+ W+ C + N + Sbjct: 753 GYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLT-GICHNEKNEVMSSQ 811 Query: 806 LTFENMAGVF-MLVAGGIVAGIFLIFIEIAYKRHKDARRKQ 845 L +NMAGVF ML A ++ I I+ + YK +A+R + Sbjct: 812 LDIDNMAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMK 852 >5UP2-B nrPDB Length = 831 Score = 292 bits (747), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 233/860 (27%), Positives = 428/860 (49%), Gaps = 63/860 (7%) Query: 9 LAVLFLFSFARAG-------CDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLN 61 + VL L++F AG ++NI +L ++ I + R + +N Sbjct: 3 MFVLLLYTFLYAGDLGHGAEKSFPVLNIAVILGRTRY--ITERDIRSLWTRDMSLDFDVN 60 Query: 62 A-TSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPI-SYTAGFYRIPVI 119 T + + + + VC+ + ++++ ++ TD I + + IP++ Sbjct: 61 VVTLLVQQTDPKSIITHVCDLMSGTKIHGVVFGDD---TDQEAIAQILDFVSSQTFIPIL 117 Query: 120 GLTTRMS-IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG-RAAQ 177 G+ S I +DK +F + QA V +M ++W HV +++ + G R Sbjct: 118 GIHGGSSMIMADKDEMSTFFQFGASIKQQATVMLNIMEEYDW-HVFSVITSNFPGYRDFI 176 Query: 178 KKLETLLEEKESKADKVLQFEPGTKNLTA-LLLEAKELEARVIILSASEDDATAVYKSAA 236 ++T ++ + T A L + K++ + VI+L S+D+AT +++ A Sbjct: 177 SFIKTTVDNSFVGWEVQNYITLDTSYTDAQTLTQLKKIHSSVILLYCSKDEATYIFEEAR 236 Query: 237 MLDMTGAGYVWLVGEREISGSA--LRYA-PDGIIGLQLIN-GKNESAHISDAVAVVAQAI 292 L + G G+VW+V ++G+ + Y P G++ + + A + D + ++ A Sbjct: 237 SLGLMGYGFVWIVPSL-VTGNTDIIPYEFPSGLVSVSYDDWDYGIEARVRDGLGIITTAA 295 Query: 293 HELFEMENITDPPRGCVGNTNIWKTGPLFK-RVLMSSKYPDGVTGRIEFNEDGDRKFANY 351 + E ++ + N PL M + DG + F EDG + Sbjct: 296 SAMLEKHSVIPEAKTSCYGQNERNDPPLHTLHNFMINVTWDG--KDLSFTEDGYQANPKL 353 Query: 352 SIMNLQ-NRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVY 410 ++ L R+ +VG + + N + +WP +++ + L IVT+ + PFV Sbjct: 354 VVLLLNMEREWEKVGKWEAKSL--NMKYPVWPRIDSDHDDNH-----LSIVTLEEAPFVI 406 Query: 411 VRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMN 469 V GTC N P +K N T G +V +CC GFC+D+L KL++ + Sbjct: 407 VENIDYLTGTCVR----NTVPCRKYF-RLANSTTEGT-SVKKCCKGFCIDILKKLSKTVK 460 Query: 470 FTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSK 529 FTY+++LV +GK G + K WNGM+GE++ +A M V LTIN ER+ ++FS Sbjct: 461 FTYDLYLVTNGKHGKKI------KNVWNGMIGEVVYKRAVMAVGSLTINEERSVAVDFSV 514 Query: 530 PFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVM-LYLLDRFSPFG--R 586 PF G++++V + + +F++PF +++W+++ + + +V+ M +++ + FSP G R Sbjct: 515 PFVETGISVMVSRSAGTVSPSAFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFSPVGYNR 574 Query: 587 FKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYT 646 ++ + T+ A+W WG++ N+ + P+ +++I+ +WA FA+I +ASYT Sbjct: 575 NLAQGKDPHGPSFTIGKAVWLLWGLVFNNSLPVQNPKGTTSKIIVSIWAFFAVIFLASYT 634 Query: 647 ANLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVELSTMYRH 703 ANLAAF++ R +++TG++D + + P D F + TV Q S + R M+++ Sbjct: 635 ANLAAFMIQRRFVDQVTGLSDNKFQRPHDYSPPFRFGTVPQGSTERNIRNN--YPDMHQY 692 Query: 704 MEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEAS--QKCDLVT--TGELFFRSGFGIG 759 M K + + +A+ +++ KL AFI+D+AVL + A + C LVT +G +F +G+GI Sbjct: 693 MVKFHQKGVQDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIA 752 Query: 760 MRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFENMAGVF-M 816 ++K S WK+ + L +L+ +G MEEL+K W+ C + N + L +NMAGVF M Sbjct: 753 LQKGSRWKRPIDLALLQFVGDGEMEELEKLWLT-GICHTEKNEVMSSQLDIDNMAGVFYM 811 Query: 817 LVAGGIVAGIFLIFIEIAYK 836 L A ++ I ++ + YK Sbjct: 812 LAAAMALSLITFVWEHLFYK 831 >5UN1-B nrPDB Length = 448 Score = 268 bits (686), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 159/467 (34%), Positives = 270/467 (57%), Gaps = 35/467 (7%) Query: 397 RLKIVTIHQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYG 455 L IVT+ + PFV V GTC N P +K I N T G + +CC G Sbjct: 3 HLSIVTLEEAPFVIVEDVDPLSGTCMR----NTVPCRKQI-RPENRTEEGGNYIKRCCKG 57 Query: 456 FCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPL 515 FC+D+L K+A+ + FTY+++LV +GK G +++N WNGM+GE+++ +A M V L Sbjct: 58 FCIDILKKIAKTVKFTYDLYLVTNGKHG--KKINGV----WNGMIGEVVTKRAYMAVGSL 111 Query: 516 TINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVM 574 TIN ER++ ++FS PF G++++V + + +F++PF + +W+++ + + +V AV Sbjct: 112 TINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVA 171 Query: 575 LYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVW 634 +++ + FSP G + T+ A+W WG++ N+ + P+ +++I+ VW Sbjct: 172 VFVFEYFSPVGY--------NGPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVW 223 Query: 635 AGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYF 691 A FA+I +ASYTANLAAF++ R ++++G++D + + P+D F + TV S + Sbjct: 224 AFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNI 283 Query: 692 RRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEAS--QKCDLVT--T 747 R M+ +M K N S +A+ +++ KL AFI+D+AVL + A + C LVT + Sbjct: 284 RNN--YLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGS 341 Query: 748 GELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APAT 805 G++F +G+GI ++KDS WK+ V L IL+ +G MEEL+ W+ C + N + Sbjct: 342 GKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLT-GICHNEKNEVMSSQ 400 Query: 806 LTFENMAGVFMLVAGGIVAGIFLIFIE-IAYKRHKDARR-KQMQLAF 850 L +NMAGVF ++A + + +E + YK +A+R K +++ F Sbjct: 401 LDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMKGLEVLF 447 >5KUF-A nrPDB Length = 877 Score = 268 bits (684), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 233/889 (26%), Positives = 413/889 (46%), Gaps = 118/889 (13%) Query: 38 HEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPA 97 E FR AVN N+ + L T++T+ I + S + ++ V+ Sbjct: 22 EELAFRFAVNTINRN----RTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFG 77 Query: 98 PTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDK-SIHLSFLRTVPPYSHQALVWFEMMR 156 P+ + + +P I + + +K S ++S P +S + ++++ Sbjct: 78 PSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLY---PDFSSLSRAILDLVQ 134 Query: 157 LFNWNHVILIVSDDHEGRAAQKKLETLLE--EKESKADKVLQFEPGTKNLTALLLEAKEL 214 F W V +V DD G +L+ L++ + + K+ Q TK+ LL E K Sbjct: 135 FFKWKTVT-VVYDDSTGLI---RLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRG 190 Query: 215 EARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISG---SALRYAPDGIIGLQL 271 + +I S + A + K A + M Y ++ ++ RY+ + G ++ Sbjct: 191 KEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRI 250 Query: 272 INGKN--------------------------------ESAHISDAVAVVAQAIHELFEME 299 +N +N ++A + DAV VV+ A+ + +M Sbjct: 251 LNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQM- 309 Query: 300 NITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNE-DGDRKFANYSIMNLQN 358 T C W+ G F ++ + + +G+TGRI FN+ +G R + +++L+ Sbjct: 310 --TVSSLQC-NRHKPWRFGTRFMSLIKEAHW-EGLTGRITFNKTNGLRTDFDLDVISLKE 365 Query: 359 RKLVQVGIFN-GSYIIQNDRKIIWPGGETERPQGYQMSTR-LKIVTIHQEPFVYVRPTTS 416 L ++G ++ S + + + P T+ +S R L + TI +EP+V + + Sbjct: 366 EGLEKIGTWDPASGLNMTESQKGKPANITD-----SLSNRSLIVTTILEEPYVLFKKSD- 419 Query: 417 DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHL 476 K + N E G+C+DLL +L+ + FTYE+ L Sbjct: 420 ---------------KPLYGNDRFE-------------GYCIDLLRELSTILGFTYEIRL 451 Query: 477 VADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGL 536 V DGK+G Q+ VN +WNGM+ EL+ +AD+ VAPLTI R + I+FSKPF G+ Sbjct: 452 VEDGKYGAQDDVNG----QWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGI 507 Query: 537 TILVKKEIPRST---LDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEE 593 +IL +K P T + SF+ P +W+ V L+ V+V+L+++ RFSP+ + + Sbjct: 508 SILYRK--PNGTNPGVFSFLNPLSPDIWMYVLLAYLGVSVVLFVIARFSPYEWYNPHPCN 565 Query: 594 EEEDAL----TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANL 649 + D + TL ++ WF G L+ G E P++ S RI+G +W F +II++SYTANL Sbjct: 566 PDSDVVENNFTLLNSFWFGVGALMQQG-SELMPKALSTRIVGGIWWFFTLIIISSYTANL 624 Query: 650 AAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELST---MYRHMEK 706 AAFL ++R E I +D + K Y V+ S +F++ ++ST M+ M Sbjct: 625 AAFLTVERMESPIDSADDLAKQT---KIEYGAVEDGSTMTFFKKS-KISTYDKMWAFMSS 680 Query: 707 HN----YESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRK 762 +S+ E IQ V + +A + +S +EF + C+L G L G+G+G Sbjct: 681 RRQSVLVKSSEEGIQRVLTSD-YALLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPM 739 Query: 763 DSPWKQNVSLNILKSHENGFMEELDKTWVRYQEC-DSRSNAPATLTFENMAGVFMLVAGG 821 SP++ +++ IL+ E G + + + W R C + S + L +N+ G+F+++A G Sbjct: 740 GSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAG 799 Query: 822 IVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEP 870 +V +F+ E YK K+A+ ++ A V R +L+ ++ + +P Sbjct: 800 LVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKP 848 >6QKC-A nrPDB Length = 915 Score = 253 bits (646), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 222/886 (25%), Positives = 403/886 (45%), Gaps = 135/886 (15%) Query: 24 PKIVNIGAVLSTKKHEQ--IFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCED 81 P + IG + ++ ++ FR A++Q + K+ L + + ++ +M C Sbjct: 30 PNNIQIGGLFPNQQSQEHAAFRFALSQLTE---PPKL-LPQIDIVNISDSFEMTYRFCSQ 85 Query: 82 LISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTV 141 S VYAI + + LT S+ + V +T + + F+ + Sbjct: 86 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 133 Query: 142 PPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE--KESKADKVLQFEP 199 P +AL+ ++ + W + I D Q+ L+T E+ + + + + E Sbjct: 134 RPELQEALI--SIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEE 191 Query: 200 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISG 256 G + L L + KE R++++ + A+ L+ G GY +++ G +I Sbjct: 192 GYRMLFQDLEKKKE---RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL 248 Query: 257 SALRYAPDGIIGLQLIN----------------------------GKNESAHISDAVAVV 288 + + + + G QL+N K SA D V V+ Sbjct: 249 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSALTYDGVKVM 308 Query: 289 AQAIHELFEMENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYPDGVTGRIEFNED 343 A+A L + I RG C+ N + W G +R L ++ +G+TG ++FNE Sbjct: 309 AEAFQSL-RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEK 366 Query: 344 GDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLK---I 400 G R ++ +++ + ++G +N D K + P + G S + + + Sbjct: 367 GRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIV 419 Query: 401 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDL 460 TI ++P+V ++ + + Y G+CV+L Sbjct: 420 TTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYCVEL 450 Query: 461 LIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNE 520 ++A+ + ++Y + +V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI Sbjct: 451 AAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLV 506 Query: 521 RAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 579 R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+ Sbjct: 507 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 566 Query: 580 RFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARIL 630 RFSP+ GR + S++ E + +++WFS G + G + +PRS S RI+ Sbjct: 567 RFSPYEWHSEEFEEGRDQTTSDQSNE--FGIFNSLWFSLGAFMQQGC-DISPRSLSGRIV 623 Query: 631 GMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIY 690 G VW F +II++SYTANLAAFL ++R I D + + Y T++ S + Sbjct: 624 GGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEF 680 Query: 691 FRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKC 742 FRR M+ +M+ + E + VR +K +A++ +S + E+ E + C Sbjct: 681 FRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPC 740 Query: 743 DLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKTWVRYQECDSRSN 801 D + G G+GI K S + V+L +LK E G +++L K W EC S+ + Sbjct: 741 DTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDS 800 Query: 802 AP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARR 843 + L+ N+AGVF ++ GG+ + + IE YK +++R Sbjct: 801 GSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKR 846 >4U1Y-A nrPDB Length = 819 Score = 233 bits (594), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 171/590 (28%), Positives = 292/590 (49%), Gaps = 68/590 (11%) Query: 275 KNESAHISDAVAVVAQAIHELFEMENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329 K SA DAV V+ +A L + I RG C+ N + W G +R L + Sbjct: 270 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 328 Query: 330 YPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERP 389 +G++G I+F+++G R +IM L+ ++G Y + D+ ++ + Sbjct: 329 V-EGLSGNIKFDQNGKRINYTINIMELKTNGPRKIG-----YWSEVDKMVVTL--TEDDT 380 Query: 390 QGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTV 449 G + T + + TI + P+V ++ E Y Sbjct: 381 SGLEQKTVV-VTTILESPYVMMKKNHEMLEGNERYE------------------------ 415 Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 G+CVDL ++A+ F Y++ +V DGK+G + +++ K WNGM+GEL+ G+AD Sbjct: 416 -----GYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR----DADTKIWNGMVGELVYGKAD 466 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSV 568 + +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + + Sbjct: 467 IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAY 526 Query: 569 HVVAVMLYLLDRFSPFGRFKVNSEEEEE--DALTLSSAMWFSWGVLLNSGIGEGAPRSFS 626 +V+V+L+L+ RFSP+ E+ EE + + ++ WF+ + G + +PRS S Sbjct: 527 ILVSVVLFLVSRFSPYEWHTEEFEDGEESTNEFGIFNSFWFALKLFFQQG-ADISPRSLS 585 Query: 627 ARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSS 686 ARI+ VW F +II++SYTANLAAFL ++R ++ I + + Y T+ S Sbjct: 586 ARIVAGVWWFFTLIIISSYTANLAAFLTVER---MVSPIESAEDLSKQTEIAYGTLDSGS 642 Query: 687 VDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EA 738 +FRR M+ +M + AE + VR +K +A++ +S + E+ E Sbjct: 643 TKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQ 702 Query: 739 SQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKTWVRYQECD 797 + CD + G G+GI K S V+L +LK E G +++L +K W EC Sbjct: 703 RKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECG 762 Query: 798 SRSNAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARR 843 ++ + + L+ N+AGVF ++ GG+ + + IE AYK +A+R Sbjct: 763 AKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKR 812 >5IDF-B nrPDB Length = 874 Score = 225 bits (573), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 170/600 (28%), Positives = 288/600 (48%), Gaps = 72/600 (12%) Query: 275 KNESAHISDAVAVVAQAIHELFEMENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329 K SA DA+ V+A+A L + + RG C+ N + W G +R L + Sbjct: 284 KYTSALTHDAILVIAEAFRYL-RRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQ 342 Query: 330 YPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERP 389 G+TG I+F+ G R NY+I ++ K+ G Y + +R + + + Sbjct: 343 V-QGMTGNIQFDTYGRR--TNYTI-DVYEMKVS--GSRKAGYWNEYERFVPFSDQQISND 396 Query: 390 QGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTV 449 + + + TI + P+V + E Y Sbjct: 397 SSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYE------------------------ 432 Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 G+CVDL ++A+ + Y++ +V DGK+G ++ K WNGM+GEL+ G+AD Sbjct: 433 -----GYCVDLAYEIAKHVGIKYKLSIVGDGKYGARD----PETKIWNGMVGELVYGRAD 483 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSV 568 + VAPLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + + Sbjct: 484 IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAY 543 Query: 569 HVVAVMLYLLDRFSPFGRFKVNSEEEEED---------ALTLSSAMWFSWGVLLNSGIGE 619 V+V+L+L+ RFSP+ ++ EE D + +++WFS G + G + Sbjct: 544 IGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGC-D 602 Query: 620 GAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIY 679 +PRS S RI+G VW F +II++SYTANLAAFL ++R I D + + Y Sbjct: 603 ISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAY 659 Query: 680 ATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSA 732 T+ S +FRR M+ +M+ ++ A+ + VR +K AF+ +S Sbjct: 660 GTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLEST 719 Query: 733 VLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKTW 790 + E+ E + CD + G G+G+ K S V+L +LK E G +++L +K W Sbjct: 720 MNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWW 779 Query: 791 VRYQECDSRSNAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQM 846 EC ++ + + L+ N+AGVF ++ GG+ + + IE YK +++R ++ Sbjct: 780 YDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKL 839 >5KUH-A nrPDB Length = 757 Score = 124 bits (311), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 135/558 (24%), Positives = 240/558 (43%), Gaps = 95/558 (17%) Query: 38 HEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPA 97 E FR AVN N+ + L T++T+ I + S + ++ V+ Sbjct: 22 EELAFRFAVNTINRN----RTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFG 77 Query: 98 PTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDK-SIHLSFLRTVPPYSHQALVWFEMMR 156 P+ + + +P I + + +K S ++S P +S + ++++ Sbjct: 78 PSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLY---PDFSSLSRAILDLVQ 134 Query: 157 LFNWNHVILIVSDDHEGRAAQKKLETLLE--EKESKADKVLQFEPGTKNLTALLLEAKEL 214 F W V +V DD G +L+ L++ + + K+ Q TK+ LL E K Sbjct: 135 FFKWKTVT-VVYDDSTGLI---RLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRG 190 Query: 215 EARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISG---SALRYAPDGIIGLQL 271 + +I S + A + K A + M Y ++ ++ RY+ + G ++ Sbjct: 191 KEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRI 250 Query: 272 INGKN--------------------------------ESAHISDAVAVVAQAIHELFEME 299 +N +N ++A + DAV VV+ A+ + +M Sbjct: 251 LNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQM- 309 Query: 300 NITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNE-DGDRKFANYSIMNLQN 358 T C W+ G F ++ + + +G+TGRI FN+ +G R + +++L+ Sbjct: 310 --TVSSLQC-NRHKPWRFGTRFMSLIKEAHW-EGLTGRITFNKTNGLRTDFDLDVISLKE 365 Query: 359 RKLVQVGIFN-GSYIIQNDRKIIWPGGETERPQGYQMSTR-LKIVTIHQEPFVYVRPTTS 416 L ++G ++ S + + + P T+ +S R L + TI +EP+V + + Sbjct: 366 EGLEKIGTWDPASGLNMTESQKGKPANITD-----SLSNRSLIVTTILEEPYVLFKKSD- 419 Query: 417 DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHL 476 K + N E G+C+DLL +L+ + FTYE+ L Sbjct: 420 ---------------KPLYGNDRFE-------------GYCIDLLRELSTILGFTYEIRL 451 Query: 477 VADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGL 536 V DGK+G Q+ VN +WNGM+ EL+ +AD+ VAPLTI R + I+FSKPF G+ Sbjct: 452 VEDGKYGAQDDVNG----QWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGI 507 Query: 537 TILVKKEIPRSTLDSFMQ 554 +IL +K P + D + Sbjct: 508 SILYRKGTPIDSADDLAK 525 Score = 83.6 bits (205), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 53/203 (26%), Positives = 101/203 (49%), Gaps = 10/203 (4%) Query: 676 KFIYATVKQSSVDIYFRRQVELST---MYRHMEKHN----YESAAEAIQAVRDNKLHAFI 728 K Y V+ S +F++ ++ST M+ M +S+ E IQ V + +A + Sbjct: 528 KIEYGAVEDGSTMTFFKKS-KISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTSD-YALL 585 Query: 729 WDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDK 788 +S +EF + C+L G L G+G+G SP++ +++ IL+ E G + + + Sbjct: 586 MESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKE 645 Query: 789 TWVRYQEC-DSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQ 847 W R C + S + L +N+ G+F+++A G+V +F+ E YK K+A+ ++ Sbjct: 646 KWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRS 705 Query: 848 LAFAAVNVWRKNLQDRKSGRAEP 870 A V R +L+ ++ + +P Sbjct: 706 FCSAMVEELRMSLKCQRRLKHKP 728 >2RC9-A nrPDB Length = 294 Score = 105 bits (263), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 53/153 (34%), Positives = 89/153 (58%), Gaps = 16/153 (10%) Query: 397 RLKIVTIHQEPFVYVRPTTSDGTCR------EEYTINGDPIKKVIC--NGPNETIPGRPT 448 L++VT+ + PFV+ R +G C + T + + ++ + N+T+P + Sbjct: 6 HLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIK-- 63 Query: 449 VPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQA 508 +CCYG+C+DLL +LA +MNF +++++V DGK+G + W G++G+LLSG A Sbjct: 64 FKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK------NGHWTGLVGDLLSGTA 117 Query: 509 DMIVAPLTINNERAQYIEFSKPFKYQGLTILVK 541 +M V +IN R+Q I+F+ PF L ILV+ Sbjct: 118 NMAVTSFSINTARSQVIDFTSPFFSTSLGILVR 150 Score = 97.1 bits (240), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 57/187 (30%), Positives = 99/187 (52%), Gaps = 21/187 (11%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE---------------ERITGINDPRLRNP 673 ++G + +G A + V S++ N A V+D ++GI+DP+L +P Sbjct: 108 LVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRGTELSGIHDPKLHHP 167 Query: 674 SDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDN--KLHAFIWDS 731 S F + TV++SS + Y R+ M+ +M ++N + + +Q ++++ KL AFI D Sbjct: 168 SQGFRFGTVRESSAEDYVRQS--FPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDK 225 Query: 732 AVLEFEAS--QKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKT 789 A+L++E S C L+T G+ F G+GIG+ +SP N+S I + +GFM+ L Sbjct: 226 ALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDK 285 Query: 790 WVRYQEC 796 W + C Sbjct: 286 WYKVVPC 292 >2RCB-A nrPDB Length = 292 Score = 103 bits (257), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 50/151 (33%), Positives = 88/151 (58%), Gaps = 14/151 (9%) Query: 397 RLKIVTIHQEPFVYVRPTTSDGTCR------EEYTINGDPIKKVICNGPNETIPGRPTVP 450 +L++VT+ + PFV+ R + DG C + T + + + N ++P T+ Sbjct: 6 KLRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPR--TLR 63 Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 +CCYG+C+DLL +LA ++ F +E+++V DGK+G W G++G+LL+G+A M Sbjct: 64 RCCYGYCIDLLERLAEDLAFDFELYIVGDGKYGALR------DGRWTGLVGDLLAGRAHM 117 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVK 541 V +IN+ R+Q ++F+ PF L I+V+ Sbjct: 118 AVTSFSINSARSQVVDFTSPFFSTSLGIMVR 148 Score = 90.9 bits (224), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 57/188 (30%), Positives = 97/188 (51%), Gaps = 23/188 (12%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLD----------------RPEERITGINDPRLRN 672 ++G + AG A + V S++ N A V+D R E ++GI+DP+L + Sbjct: 106 LVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRTRGTE-LSGIHDPKLHH 164 Query: 673 PSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDN--KLHAFIWD 730 PS F + TV +SS + Y + M+ HM +H+ + + + + KL+AFI D Sbjct: 165 PSQGFRFGTVWESSAEAYIK--ASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMD 222 Query: 731 SAVLEFEAS--QKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDK 788 ++L++E S C L+T G+ F G+GIG+ ++SP N+S I + +GF++ L Sbjct: 223 KSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHD 282 Query: 789 TWVRYQEC 796 W + C Sbjct: 283 KWYKMVPC 290 >5H8N-A nrPDB Length = 285 Score = 101 bits (251), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 62/151 (41%), Positives = 90/151 (59%), Gaps = 21/151 (13%) Query: 397 RLKIVTIHQEPFVYVR---PTTSDGTCREEYTINGDPIKKV--ICNGPNETIPGRPTVPQ 451 L IVT+ + PFV V P T TC N P +K I N NE + V + Sbjct: 7 HLSIVTLEEAPFVIVEDIDPLTE--TCVR----NTVPCRKFVKINNSTNEGM----NVKK 56 Query: 452 CCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMI 511 CC GFC+D+L KL+R + FTY+++LV +GK G ++VNN WNGM+GE++ +A M Sbjct: 57 CCKGFCIDILKKLSRTVKFTYDLYLVTNGKHG--KKVNNV----WNGMIGEVVYQRAVMA 110 Query: 512 VAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 V LTIN ER++ ++FS PF G++++V + Sbjct: 111 VGSLTINEERSEVVDFSVPFVETGISVMVSR 141 Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 47/138 (34%), Positives = 82/138 (59%), Gaps = 9/138 (6%) Query: 661 RITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQ 717 ++TG++D + + P D F + TV S + R M+++M K N + +A+ Sbjct: 144 QVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPY--MHQYMTKFNQKGVEDALV 201 Query: 718 AVRDNKLHAFIWDSAVLEFEAS--QKCDLVT--TGELFFRSGFGIGMRKDSPWKQNVSLN 773 +++ KL AFI+D+AVL ++A + C LVT +G +F +G+GI ++K SPWK+ + L Sbjct: 202 SLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLA 261 Query: 774 ILKSHENGFMEELDKTWV 791 +L+ +G MEEL+ W+ Sbjct: 262 LLQFVGDGEMEELETLWL 279 >3OEK-A nrPDB Length = 286 Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 53/164 (32%), Positives = 90/164 (54%), Gaps = 13/164 (7%) Query: 395 STRLKIVTIHQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCC 453 + L + T+ + PFV V P GTC + + + P+ P + +CC Sbjct: 4 TQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEK----RCC 59 Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 GFC+D+L +LA + F+Y+++LV +GK G ++++ WNGM+GE+ +ADM + Sbjct: 60 KGFCIDILKRLAHTIGFSYDLYLVTNGKHG--KKIDGV----WNGMIGEVFYQRADMAIG 113 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDS--FMQP 555 LTIN ER++ ++FS PF G++++V + S L F +P Sbjct: 114 SLTINEERSEIVDFSVPFVETGISVMVARGTTVSGLSDRKFQRP 157 Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 40/137 (29%), Positives = 77/137 (56%), Gaps = 9/137 (6%) Query: 662 ITGINDPRLRNPSDKFI---YATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQA 718 ++G++D + + P +++ + TV S + R M+ +M ++N EA+ Sbjct: 146 VSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSN--YPDMHSYMVRYNQPRVEEALTQ 203 Query: 719 VRDNKLHAFIWDSAVLEFEA--SQKCDLVT--TGELFFRSGFGIGMRKDSPWKQNVSLNI 774 ++ KL AFI+D+AVL + A + C LVT +G++F +G+GI + K S WK+ + L + Sbjct: 204 LKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLAL 263 Query: 775 LKSHENGFMEELDKTWV 791 L+ + +E L++ W+ Sbjct: 264 LQFLGDDEIEMLERLWL 280 >4IGR-A nrPDB Length = 258 Score = 95.9 bits (237), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 45/100 (45%), Positives = 67/100 (67%), Gaps = 5/100 (5%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C+DLL +LA + F+YE+ LV DGK+G Q+ +K +WNGM+ EL+ +AD+ VAP Sbjct: 36 GYCIDLLKELAHILGFSYEIRLVEDGKYGAQD-----DKGQWNGMVKELIDHKADLAVAP 90 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 LTI + R + I+FSKPF G++IL +K P + D + Sbjct: 91 LTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAK 130 Score = 45.8 bits (107), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 16/131 (12%) Query: 676 KFIYATVKQSSVDIYFRRQVELST---MYRHME-------KHNYESAAEAIQAVRDNKLH 725 K Y VK + +F++ ++ST M+ M K+N E + A + Sbjct: 133 KIEYGAVKDGATMTFFKKS-KISTFEKMWAFMSSKPSALVKNNEEGIQRTLTAD-----Y 186 Query: 726 AFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEE 785 A + +S +E+ + C+L G L G+GIG SP++ +++ IL+ E + Sbjct: 187 ALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHI 246 Query: 786 LDKTWVRYQEC 796 + + W R C Sbjct: 247 MKEKWWRGSGC 257 >2XXT-A nrPDB Length = 261 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 45/100 (45%), Positives = 65/100 (65%), Gaps = 4/100 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C+DLL +L+ + FTYE+ LV DGK+G Q+ VN +WNGM+ EL+ +AD+ VAP Sbjct: 34 GYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNG----QWNGMVRELIDHKADLAVAP 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 L I R + I+FSKPF G++IL +K P + D + Sbjct: 90 LAITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAK 129 Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 9/128 (7%) Query: 676 KFIYATVKQSSVDIYFRRQVELST---MYRHMEKHN----YESAAEAIQAVRDNKLHAFI 728 K Y V+ + +F++ ++ST M+ M +S E IQ V + +AF+ Sbjct: 132 KIEYGAVEDGATMTFFKKS-KISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD-YAFL 189 Query: 729 WDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDK 788 +S +EF + C+L G L G+G+G SP++ +++ IL+ E G + + + Sbjct: 190 MESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKE 249 Query: 789 TWVRYQEC 796 W R C Sbjct: 250 KWWRGNGC 257 >5O9A-A nrPDB Length = 264 Score = 93.2 bits (230), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 41/91 (45%), Positives = 64/91 (70%), Gaps = 4/91 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+CVDL ++A+ F Y++ +V DGK+G + +++ K WNGM+GEL+ G+AD+ +AP Sbjct: 34 GYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR----DADTKIWNGMVGELVYGKADIAIAP 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 LTI R + I+FSKPF G++I++KK P Sbjct: 90 LTITYVREEVIDFSKPFMSLGISIMIKKGTP 120 Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 9/129 (6%) Query: 679 YATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDS 731 Y T+ S +FRR M+ +M + AE + VR +K +A++ +S Sbjct: 135 YGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLES 194 Query: 732 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKT 789 + E+ E + CD + G G+GI K S V+L +LK E G +++L +K Sbjct: 195 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKW 254 Query: 790 WVRYQECDS 798 W EC S Sbjct: 255 WYDKGECGS 263 >4MF3-A nrPDB Length = 261 Score = 92.4 bits (228), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 45/100 (45%), Positives = 65/100 (65%), Gaps = 5/100 (5%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C+DLL +L+ + F Y+V LV DGK+G Q ++K EWNGM+ EL+ +AD+ VAP Sbjct: 35 GYCLDLLKELSNILGFIYDVKLVPDGKYGAQ-----NDKGEWNGMVKELIDHRADLAVAP 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 LTI R + I+FSKPF G++IL +K P + D + Sbjct: 90 LTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAK 129 Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 59/128 (46%), Gaps = 9/128 (7%) Query: 676 KFIYATVKQSSVDIYFRRQVELST---MYRHMEKHN----YESAAEAIQAVRDNKLHAFI 728 K Y V+ S +F++ ++ST M+ M ++ E IQ V +A + Sbjct: 132 KIEYGAVRDGSTMTFFKKS-KISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTD-YALL 189 Query: 729 WDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDK 788 +S +E+ + C+L G L G+G+G SP++ +++ IL+ E G + + + Sbjct: 190 MESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKE 249 Query: 789 TWVRYQEC 796 W R C Sbjct: 250 KWWRGNGC 257 >1YAE-A nrPDB Length = 312 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 43/88 (48%), Positives = 61/88 (69%), Gaps = 4/88 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C+DLL +L+ + FTYE+ LV DGK+G Q+ VN +WNGM+ EL+ +AD+ VAP Sbjct: 43 GYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNG----QWNGMVRELIDHKADLAVAP 98 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKK 542 L I R + I+FSKPF G++IL +K Sbjct: 99 LAITYVREKVIDFSKPFMTLGISILYRK 126 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 10/143 (6%) Query: 676 KFIYATVKQSSVDIYFRRQVELST---MYRHMEKHN----YESAAEAIQAVRDNKLHAFI 728 K Y V+ + +F++ ++ST M+ M +S E IQ V + +AF+ Sbjct: 166 KIEYGAVEDGATMTFFKKS-KISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD-YAFL 223 Query: 729 WDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDK 788 +S +EF + C+L G L G+G+G SP++ +++ IL+ E G + + + Sbjct: 224 MESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKE 283 Query: 789 TWVRYQEC-DSRSNAPATLTFEN 810 W R C + S + L +N Sbjct: 284 KWWRGNGCPEEESKEASALGVQN 306 >3DP4-A nrPDB Length = 278 Score = 89.4 bits (220), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 41/91 (45%), Positives = 62/91 (68%), Gaps = 4/91 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+CVDL ++A+ + Y++ +V DGK+G + + K WNGM+GEL+ G+AD+ VAP Sbjct: 50 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR----DPETKIWNGMVGELVYGRADIAVAP 105 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 LTI R + I+FSKPF G++I++KK P Sbjct: 106 LTITLVREEVIDFSKPFMSLGISIMIKKGTP 136 Score = 45.8 bits (107), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 9/127 (7%) Query: 679 YATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKLH-AFIWDS 731 Y T+ S +FRR M+ +M+ ++ A+ + VR +K AF+ +S Sbjct: 151 YGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLES 210 Query: 732 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKT 789 + E+ E + CD + G G+G+ K S V+L +LK E G +++L +K Sbjct: 211 TMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKW 270 Query: 790 WVRYQEC 796 W EC Sbjct: 271 WYDKGEC 277 >3FAT-A nrPDB Length = 260 Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 39/91 (42%), Positives = 64/91 (70%), Gaps = 4/91 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+CVDL ++A+ + Y++ +V DGK+G + +++ K WNGM+GEL+ G+A++ +AP Sbjct: 32 GYCVDLASEIAKHIGIKYKIAIVPDGKYGAR----DADTKIWNGMVGELVYGKAEIAIAP 87 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 LTI R + I+FSKPF G++I++KK P Sbjct: 88 LTITLVREEVIDFSKPFMSLGISIMIKKGTP 118 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 60/127 (47%), Gaps = 9/127 (7%) Query: 679 YATVKQSSVDIYFRRQV-----ELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWDS 731 Y T+ S +FRR ++ T R E + + AE + VR +K AF+ +S Sbjct: 133 YGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLES 192 Query: 732 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKT 789 + E+ E + CD + G G+G+ K S + V+L +LK E G +++L +K Sbjct: 193 TMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKW 252 Query: 790 WVRYQEC 796 W EC Sbjct: 253 WYDKGEC 259 >5IKB-A nrPDB Length = 257 Score = 86.7 bits (213), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 43/98 (43%), Positives = 61/98 (62%), Gaps = 5/98 (5%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GFCVD+L +LA + F Y++ LV DG +G E W GM+GEL++ +AD+ VA Sbjct: 34 GFCVDMLKELAEILRFNYKIRLVGDGVYGVPEA-----NGTWTGMVGELIARKADLAVAG 88 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 LTI ER + I+FSKPF G++IL +K P ++D Sbjct: 89 LTITAEREKVIDFSKPFMTLGISILYRKGTPIESVDDL 126 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 7/124 (5%) Query: 679 YATVKQSSVDIYFRR------QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSA 732 Y T+ S +F+ Q + MY +S E I V N +AF+ +S Sbjct: 134 YGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVL-NSNYAFLLEST 192 Query: 733 VLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVR 792 + E+ + C+L G L G+GIGM S ++ L IL+ EN +E L + W Sbjct: 193 MNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWE 252 Query: 793 YQEC 796 +C Sbjct: 253 GGKC 256 >5DT6-A nrPDB Length = 267 Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 38/94 (40%), Positives = 58/94 (61%), Gaps = 3/94 (3%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C DL LA ++ YE+ LV DG +G + N W+GM+GEL+ +AD+ ++ Sbjct: 39 GYCKDLADMLAAQLGIKYEIRLVQDGNYGAE---NQYAPGGWDGMVGELIRKEADIAISA 95 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRST 548 +TI ER + I+FSKPF G++I++KK P T Sbjct: 96 MTITAERERVIDFSKPFMTLGISIMIKKGTPIKT 129 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 62/127 (48%), Gaps = 8/127 (6%) Query: 679 YATVKQSSVDIYFRR-QVEL-STMYRHM---EKHNYESAAEAIQAVRDNK-LHAFIWDSA 732 Y T+ S +FRR Q+ L + M+ +M + H+ + E I+ VR +K +A + +S Sbjct: 141 YGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRRVRQSKGKYALLVESP 200 Query: 733 VLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKTW 790 E+ A CD + G GFG+ SP ++ ++ +L ENG + + +K W Sbjct: 201 KNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWW 260 Query: 791 VRYQECD 797 EC+ Sbjct: 261 FDKTECN 267 >5EHM-A nrPDB Length = 268 Score = 80.1 bits (196), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 36/91 (39%), Positives = 59/91 (64%), Gaps = 4/91 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+ VDL+ ++++ + F Y++ LV DG +G+ ++ EWNGM+ ELL +AD+ +A Sbjct: 38 GYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTG----EWNGMIRELLEQRADLAIAD 93 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 LTI ER Q ++F+ PF G++IL +K P Sbjct: 94 LTITFEREQAVDFTTPFMNLGVSILYRKGTP 124 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 9/120 (7%) Query: 679 YATVKQSSVDIYFRRQVELST---MYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWD 730 Y +K S +FR ++ST M+ ME S E ++ V K +AF+ + Sbjct: 139 YGALKGGSTAAFFR-DSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLME 197 Query: 731 SAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTW 790 S +E+ + C+L G + +GI +SP++ ++ ILK E G + L W Sbjct: 198 STSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKW 257 >5L2E-A nrPDB Length = 688 Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 123/584 (21%), Positives = 224/584 (38%), Gaps = 125/584 (21%) Query: 26 IVNIGAVL--STKKHEQIFREAVNQANKRH---FTRKIQLNATSVTHRPNAIQMALSVCE 80 I++IGA+ S KK +++FR AV N+ T KI + T V N Q CE Sbjct: 5 IIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGN-NPFQAVQEACE 63 Query: 81 DLISSQVYAILVS---------HPPAPTDHLTPTPIS-YTAGFYRIPVIGLTTRMSIYSD 130 L++ + A++ S A H+ I TAG P G S +D Sbjct: 64 -LMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAG---TPRSGCGLTRSNRND 119 Query: 131 KSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESK 190 + +V P + V ++ + W I+ +++ R Q+ L+ + + Sbjct: 120 -----DYTLSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKV---SQQG 171 Query: 191 ADKVLQ-FEPGTKNLTALLLEAKELEA--------RVIILSASEDDATAVYKSAAMLDMT 241 D LQ E + L + +E R IL + A + ++ Sbjct: 172 MDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLV 231 Query: 242 GAGYVWLVGEREISGSALRY-----------------APDGI----------IGLQLING 274 W++ EI+ ++ P I I L + Sbjct: 232 AFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDP 291 Query: 275 KNESAH--------ISDAVAVVAQAIH-ELFEMENITDPPRGCV-GNTNIWKTGPLFKRV 324 K+ A I D V ++A A H +L + + + C+ N+ W+ G Sbjct: 292 KDPFAQNMEISNLYIYDTVLLLANAFHKKLQDRKWHSMASLSCIRKNSKPWQGGRSMLET 351 Query: 325 LMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQ-----NRKLVQVGIFNGSYIIQNDRKI 379 + +G+TG +EF E+G ++ I+ R + ++G +N + Sbjct: 352 IKKGGV-NGLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLN----- 405 Query: 380 IWPGGETERPQGYQM-STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNG 438 G T++ M L++VT+ +EPFV V Sbjct: 406 ---GSLTDKKLENNMRGVVLRVVTVLEEPFVMV--------------------------- 435 Query: 439 PNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNG 498 +E + G+P Q GF +D+L L+ + F YE+++ D K+G+ + WNG Sbjct: 436 -SENVLGKPKKYQ---GFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQE-----DGTWNG 486 Query: 499 MMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 ++GEL+ +AD+ ++ LTI +R ++F+ + + +L+++ Sbjct: 487 LVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRR 530 Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 42/132 (31%), Positives = 65/132 (49%), Gaps = 12/132 (9%) Query: 675 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHN------YESAAEAIQAVRDNKLHAFI 728 D +Y V+ ++ F R S M+R + + N ES A IQ V+ +AF+ Sbjct: 553 DSAVYQHVRMKGLNP-FERDSMYSQMWRMINRSNGSENNVLESQA-GIQKVKYGN-YAFV 609 Query: 729 WDSAVLEFEA--SQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL 786 WD+AVLE+ A C T G G+GI ++ SP++ S IL+ ++G M+ L Sbjct: 610 WDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDIL 669 Query: 787 D-KTWVRYQECD 797 K W + +CD Sbjct: 670 KHKWWPKNGQCD 681 >4YKP-A nrPDB Length = 256 Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 35/93 (37%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 C G D+++KL+ ++ FTYE D KFG + N EWNGM+ +LL + DM Sbjct: 32 DCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTN----EWNGMIRDLLDDKTDM 87 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 I L+ N+ R I++S PF G+ +VK E Sbjct: 88 IAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGE 120 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 715 AIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNI 774 AI+ +R L FI + VL CD+ + GE F + G+ KDSP+K + ++ Sbjct: 174 AIETLR-GGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHL 232 Query: 775 LKSHENGFMEELDKTW 790 LK E GF++ L + W Sbjct: 233 LKFREEGFIDILWEKW 248 >5CC2-A nrPDB Length = 265 Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 37/145 (25%), Positives = 71/145 (48%), Gaps = 36/145 (24%) Query: 398 LKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFC 457 L++VT+ +EPFV V +E + G+P Q GF Sbjct: 5 LRVVTVLEEPFVMV----------------------------SENVLGKPKKYQ---GFS 33 Query: 458 VDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTI 517 +D+L L+ + F YE+++ D K+G+ + WNG++GEL+ +AD+ ++ LTI Sbjct: 34 IDVLDALSNYLGFNYEIYVAPDHKYGSPQE-----DGTWNGLVGELVFKRADIGISALTI 88 Query: 518 NNERAQYIEFSKPFKYQGLTILVKK 542 +R ++F+ + + +L+++ Sbjct: 89 TPDRENVVDFTTRYMDYSVGVLLRR 113 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 42/132 (31%), Positives = 65/132 (49%), Gaps = 12/132 (9%) Query: 675 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHN------YESAAEAIQAVRDNKLHAFI 728 D +Y V+ ++ F R S M+R + + N ES A IQ V+ +AF+ Sbjct: 136 DSAVYQHVRMKGLNP-FERDSMYSQMWRMINRSNGSENNVLESQA-GIQKVKYGN-YAFV 192 Query: 729 WDSAVLEFEA--SQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL 786 WD+AVLE+ A C T G G+GI ++ SP++ S IL+ ++G M+ L Sbjct: 193 WDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDIL 252 Query: 787 D-KTWVRYQECD 797 K W + +CD Sbjct: 253 KHKWWPKNGQCD 264 >5K5S-A nrPDB Length = 615 Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 46/178 (25%), Positives = 81/178 (45%), Gaps = 9/178 (5%) Query: 105 TPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVI 164 T ++ G + IP + + + S+K+ SFLRT+P HQA +++ F WN V Sbjct: 151 TAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVG 210 Query: 165 LIVSDDHEGRAAQKKLETLLEEKESKAD--KVLQFEPGTKNLTALLLEAKELEARVIILS 222 I +DD GR +K EE++ D +++ + + ++ + A+VI++ Sbjct: 211 TIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVF 270 Query: 223 ASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALR-----YAPDGIIGLQLINGK 275 +S D + K ++TG +WL E S S + + G IG L G+ Sbjct: 271 SSGPDLEPLIKEIVRRNITGK--IWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQ 326 >4ZDM-A nrPDB Length = 261 Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 P C G V+++ +++++NFTY D KFG + NS EWNG++ +LL + D Sbjct: 34 PSCYTGVNVEIVSMMSQDLNFTYNFITPEDLKFGGK----NSTTGEWNGLIRDLLDNKTD 89 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 MIV L+ N R I+FS GL LVK + Sbjct: 90 MIVVALSNNAVRKADIDFSLSMMDGGLGALVKSD 123 Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 711 SAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNV 770 S E ++ +R FI + + + +CD+V GE F G+RK+SP+K V Sbjct: 173 SYGEGLERMRAGGF-VFIDEIPGINYATKGECDIVQIGETFQPFELAFGLRKNSPFKNLV 231 Query: 771 SLNILKSHENGFMEELDKTWVRYQ 794 +L E G + EL + +Y+ Sbjct: 232 DTFMLGIREQGVISEL---YAKYE 252 >5FBH-B nrPDB Length = 568 Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 46/178 (25%), Positives = 81/178 (45%), Gaps = 9/178 (5%) Query: 105 TPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVI 164 T ++ G + IP + + + S+K+ SFLRT+P HQA +++ F WN V Sbjct: 178 TAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVG 237 Query: 165 LIVSDDHEGRAAQKKLETLLEEKESKAD--KVLQFEPGTKNLTALLLEAKELEARVIILS 222 I +DD GR +K EE++ D +++ + + ++ + A+VI++ Sbjct: 238 TIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVF 297 Query: 223 ASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALR-----YAPDGIIGLQLINGK 275 +S D + K ++TG +WL E S S + + G IG L G+ Sbjct: 298 SSGPDLEPLIKEIVRRNITGK--IWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQ 353 >4WXJ-A nrPDB Length = 269 Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 4/88 (4%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+ VDL+ LA+E F + V D K+G+ + +N EW+G++ +L+ A + + Sbjct: 41 GYAVDLIYMLAQECKFDFNFEPVRDNKYGSYD----ANTDEWDGIIRQLIDNNAQIGICD 96 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKK 542 LTI R ++F+ PF G++IL K Sbjct: 97 LTITQARRSVVDFTVPFMQLGISILSYK 124 Score = 42.4 bits (98), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 29/132 (21%), Positives = 62/132 (46%), Gaps = 9/132 (6%) Query: 675 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAA------EAIQAVRDNK-LHAF 727 +K + T++ + +YF + + +++ A E + V+ +K +AF Sbjct: 138 NKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAF 197 Query: 728 IWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD 787 + ++ L++ + C+L GE F +GI + ++ ++ N+S+ IL+ E G + +L Sbjct: 198 LMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLR 257 Query: 788 KTWVRYQE--CD 797 W E CD Sbjct: 258 NKWFNSNESTCD 269 >5CNI-A nrPDB Length = 503 Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 20/171 (11%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 ++IP I + + SDKS + F RTVPP QA E++R FNW +V + S E Sbjct: 159 LFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVAS---E 215 Query: 173 GRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLEA------KELEARVIILSASED 226 G + +E E ++ V E + ++ E ++ ARV +L + Sbjct: 216 GDYGETGIEAFELEARARNISVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSE 275 Query: 227 DATAVYKSAAMLDMTGAGYVWLVG------EREISGSALRYAPDGIIGLQL 271 DA + ++ L+ A + W+ E ++GS A +G I ++L Sbjct: 276 DARELLAASQRLN---ASFTWVASDGWGALEEVVAGS--EGAAEGAITIEL 321 >2E4V-A nrPDB Length = 555 Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 12/145 (8%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 ++IP I + + SDKS + F RTVPP +QA E++R FNW +V + S E Sbjct: 139 LFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVAS---E 195 Query: 173 GRAAQKKLETLLEEKE------SKADKVLQFEPGTKNLTALLLEAKELEARVIILSASED 226 G + +E +E + A+KV + + + ++ ARV++L D Sbjct: 196 GDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSD 255 Query: 227 DATAVYKSAAMLDMTGAGYVWLVGE 251 D+ + +A + A + W+ + Sbjct: 256 DSRELIAAA---NRVNASFTWVASD 277 >5CNM-A nrPDB Length = 517 Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 39/145 (26%), Positives = 69/145 (47%), Gaps = 12/145 (8%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 ++IP I + + SDKS + F RTVPP +QA E++R FNW +V + S E Sbjct: 165 LFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVAS---E 221 Query: 173 GRAAQKKLETLLEEKESKADKVLQFEP-GTKNL----TALLLE-AKELEARVIILSASED 226 G + +E +E + + E G N+ +++ E ++ ARV++L D Sbjct: 222 GDYGETGIEAFEQEARLRNISIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSD 281 Query: 227 DATAVYKSAAMLDMTGAGYVWLVGE 251 D+ + +A+ A + W+ + Sbjct: 282 DSRELIAAAS---RANASFTWVASD 303 >5KZQ-A nrPDB Length = 570 Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 12/145 (8%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 ++IP I + + SDKS + F RTVPP QA E++R FNW +V + S E Sbjct: 157 LFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVAS---E 213 Query: 173 GRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLEA------KELEARVIILSASED 226 G + +E E ++ V E + ++ E ++ ARV +L + Sbjct: 214 GDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSE 273 Query: 227 DATAVYKSAAMLDMTGAGYVWLVGE 251 DA + ++ L+ A + W+ + Sbjct: 274 DARELLAASQRLN---ASFTWVASD 295 >5X2M-A nrPDB Length = 461 Score = 50.4 bits (119), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 12/175 (6%) Query: 80 EDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLR 139 ED + AI V P T L+ PI T F P++ S++S ++++ SFLR Sbjct: 105 EDASTGLPNAIGVVGPFTSTHALSIAPIFMTNLF---PMVSYGCSGSVFSKENLYPSFLR 161 Query: 140 TVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEP 199 TV ++ FNW V + SDD G+ ++ + +E+ E L F Sbjct: 162 TVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSE----ICLAFYK 217 Query: 200 GTKNLTALLLEAKELEA---RVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGE 251 T L K++E +VI++ A + A AV +SA L++T VW+ + Sbjct: 218 AINVNTDYLQVFKQIEEQNIKVIVVFAPKVYAEAVVESAVQLNVTNK--VWIADD 270 >6BT5-A nrPDB Length = 479 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 36/142 (25%), Positives = 70/142 (49%), Gaps = 9/142 (6%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 ++IP I + SD + + F R VPP S+QA +++ WN+V + S+ + Sbjct: 132 LFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNY 191 Query: 173 GRAAQKKLETLLEE----KESKADKV-LQFEPGT-KNLTALLLEAKELEARVIILSASED 226 G + + + E +++ K+ + PG + + LLE AR +I+ A+ED Sbjct: 192 GESGVEAFTQISREIGGVSIAQSQKIPREPRPGEFEKIIKRLLETP--NARAVIMFANED 249 Query: 227 DATAVYKSAAMLDMTGAGYVWL 248 D + ++A L+ +G ++W+ Sbjct: 250 DIRRILEAAKKLNQSGH-FLWI 270 >5TUJ-C nrPDB Length = 235 Score = 47.0 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 17/89 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL LA+E+ E W+G++ L +G+ D++++ Sbjct: 36 GFDIDLAKALAKELGVKVEF-----------------VPTTWDGIIPALQTGKFDIVMSG 78 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKE 543 +TI ER + ++FS P+ G TILVKK+ Sbjct: 79 MTITPERKKKVDFSDPYMTAGQTILVKKD 107 >5X2N-B nrPDB Length = 478 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 40/82 (48%) Query: 105 TPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVI 164 T I GF+ +P I +SD ++ SF RTVP Q ++++ FNWN V Sbjct: 135 TVIGKLLGFFLMPQISFGATSDKFSDSLVYPSFFRTVPSDIRQVDAMVQLIKKFNWNWVA 194 Query: 165 LIVSDDHEGRAAQKKLETLLEE 186 ++ S++ G+ ++ E+ Sbjct: 195 VVGSEEEYGQQGVQQFSKKAED 216 >4IO3-A nrPDB Length = 248 Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 31/55 (56%) Query: 742 CDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQEC 796 C+L GE F +S FGI K+ + +++ +NIL E G ++ L K W + + C Sbjct: 193 CNLTLVGEDFDKSTFGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKAC 247 >5C5C-A nrPDB Length = 481 Score = 42.7 bits (99), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 34/151 (22%), Positives = 67/151 (44%), Gaps = 25/151 (16%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 ++IP I + SD + F R VPP S QA ++++ WN+V + S E Sbjct: 139 LFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLAS---E 195 Query: 173 GRAAQKKLETLLE-EKES--------------KADKVLQFEPGTKNLTALLLEAKELEAR 217 G +K +E+ + KE+ + D+ + F+ + LL+ +R Sbjct: 196 GSYGEKGVESFTQISKEAGGLSIAQSVRIPQERKDRTIDFD----RIIKQLLDTP--NSR 249 Query: 218 VIILSASEDDATAVYKSAAMLDMTGAGYVWL 248 +++ A+++D + +A D G ++W+ Sbjct: 250 AVVIFANDEDIKQILAAAKRADQVGH-FLWV 279 >4ZV2-A nrPDB Length = 233 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 33/48 (68%) Query: 495 EWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 +++G++ L SG+ D+++A +TI ER + ++FS P+ G I+VKK Sbjct: 57 DFDGIIPALQSGKIDVVIAGMTITEERKKQVDFSDPYFEAGQAIVVKK 104 >4F3S-A nrPDB Length = 255 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 28/36 (77%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPF 531 W+GM+G + SGQAD+ + ++I ++R + I+FS+P+ Sbjct: 57 WDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPY 92 >2Q2A-A nrPDB Length = 272 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 18/97 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF VDLL + + YE+ + W+ + L S + DM ++ Sbjct: 65 GFDVDLLDAVMKAAGLDYELKNIG-----------------WDPLFASLQSKEVDMGISG 107 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP-RSTLD 550 +TI +ER Q +FS P+ ILVK+ P ++ LD Sbjct: 108 ITITDERKQSYDFSDPYFEATQVILVKQGSPVKNALD 144 >1GGG-A nrPDB Length = 226 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 17/87 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF VDL +A+E+ YE+ +++G++ L + D+ +A Sbjct: 26 GFDVDLWAAIAKELKLDYEL-----------------KPMDFSGIIPALQTKNVDLALAG 68 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVK 541 +TI +ER + I+FS + GL ++VK Sbjct: 69 ITITDERKKAIDFSDGYYKSGLLVMVK 95 >1YK0-A nrPDB Length = 480 Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust. Identities = 35/156 (22%), Positives = 63/156 (40%), Gaps = 5/156 (3%) Query: 97 APTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFL-RTVPPYSHQALVWFEMM 155 P P++ A + +P++ + + K S L R P Y+ + + Sbjct: 133 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALF 192 Query: 156 RLFNWNHVILIVSDDHEGRAAQKKLETLLE--EKESKADKVLQFEPGTKNLT-ALLLEAK 212 R +W+ L+ SDD R LE + E ++E + F+ TK+L ++ Sbjct: 193 RHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDE-TKDLDLEDIVRNI 251 Query: 213 ELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWL 248 + RV+I+ AS D ++ A MT Y + Sbjct: 252 QASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFF 287 >2PYY-A nrPDB Length = 228 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Query: 714 EAIQAVRDNKLHAFIWDSAVLEFEASQ--KCDLVTTGELFFRSGFGIGMRKDSPWKQNVS 771 EA +A++ K A ++D+ VL F A+ K + G + +GI + +SP+++ ++ Sbjct: 142 EAYKALQTKKADAVVFDAPVLLFYAANEGKGKVEIVGSILREESYGIILPNNSPYRKPIN 201 Query: 772 LNILKSHENGFMEELDKTW 790 +L ENG + L W Sbjct: 202 QALLNLKENGTYQSLYDKW 220 >4PSH-A nrPDB Length = 227 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 17/89 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF VDL ++AR + ++ D F +G++ LL+ + D+I++ Sbjct: 33 GFDVDLAKEIARRLGVELKI---VDMTF--------------DGLIPSLLTKKIDVIISG 75 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKE 543 +TI ER + + FS P+ G I+V+K+ Sbjct: 76 MTITEERKKVVAFSDPYFDAGQVIVVRKD 104 >5OTA-A nrPDB Length = 265 Score = 38.9 bits (89), Expect = 0.011, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 17/91 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL L + MN E V ++ W+G++ L +G+ D I+A Sbjct: 29 GFDIDLGNDLCKRMNI--ECKFV---------------EQAWDGIIPSLTAGRYDAIMAA 71 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 + I R + I FS+P+ +T L + P Sbjct: 72 MGIQPAREKVIAFSRPYLLTPMTFLTTADSP 102 >6FXG-A nrPDB Length = 227 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 ++ + L +GQ D I+A +TI +ER + +FS P+ LTI K+ Sbjct: 52 FDAALQNLKAGQVDGIIAGMTITDERKETFDFSNPYYTSALTIATTKD 99 >4KPT-A nrPDB Length = 251 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 ++ + L +GQ D I+A +TI +ER + +FS P+ LTI K+ Sbjct: 76 FDAALQNLKAGQVDGIIAGMTITDERKETFDFSNPYYTSALTIATTKD 123 >4ZEF-A nrPDB Length = 251 Score = 38.5 bits (88), Expect = 0.013, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 17/88 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G VDL+ + A FT E + ++ + + SGQAD +VA Sbjct: 52 GIDVDLVKRAAELQGFTVEFKFIG-----------------FSSAVQAVESGQADGMVAG 94 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKK 542 +TI ++R + +FS P+ G+ I VKK Sbjct: 95 MTITDDRKKAFDFSVPYFDSGIQIAVKK 122 >1ISS-A nrPDB Length = 490 Score = 38.5 bits (88), Expect = 0.015, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 36/71 (50%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 + IP I + SDK+++ FLR VP + QA ++++ +NW +V + ++ + Sbjct: 145 LFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNY 204 Query: 173 GRAAQKKLETL 183 G + + L Sbjct: 205 GESGMDAFKEL 215 >3K4U-A nrPDB Length = 245 Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 34/53 (64%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRST 548 W+G++ L++ + D+I++ +TI+ ER + F +P+ G ++LVKK + + Sbjct: 53 WDGLIPGLVTEKFDIIISGMTISQERNLRVNFVEPYIVVGQSLLVKKGLEKGV 105 >3LMK-A nrPDB Length = 492 Score = 37.4 bits (85), Expect = 0.029, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 36/71 (50%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 + IP I + SDK++ F+R VP + QA ++++ +NW +V + ++ + Sbjct: 151 LFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNY 210 Query: 173 GRAAQKKLETL 183 G + + + + Sbjct: 211 GESGMEAFKDM 221 >6N4Y-A nrPDB Length = 596 Score = 37.4 bits (85), Expect = 0.031, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 36/71 (50%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 + IP I + SDK++ F+R VP + QA ++++ +NW +V + ++ + Sbjct: 181 LFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNY 240 Query: 173 GRAAQKKLETL 183 G + + + + Sbjct: 241 GESGMEAFKDM 251 >4F3P-A nrPDB Length = 249 Score = 36.6 bits (83), Expect = 0.045, Method: Compositional matrix adjust. Identities = 21/87 (24%), Positives = 43/87 (49%), Gaps = 17/87 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL ++A+ +TY++ + ++ G++ L + D+ ++ Sbjct: 47 GFDLDLWAEIAKGAGWTYKIQPM-----------------DFAGLIPALQTQNIDVALSG 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVK 541 +TI ER + I+FS P+ GL +V+ Sbjct: 90 MTIKEERRKAIDFSDPYYDSGLAAMVQ 116 >6N4X-A nrPDB Length = 877 Score = 36.6 bits (83), Expect = 0.051, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 36/71 (50%) Query: 113 FYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHE 172 + IP I + SDK++ F+R VP + QA ++++ +NW +V + ++ + Sbjct: 170 LFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNY 229 Query: 173 GRAAQKKLETL 183 G + + + + Sbjct: 230 GESGMEAFKDM 240 >3I6V-A nrPDB Length = 232 Score = 36.6 bits (83), Expect = 0.056, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 27/39 (69%) Query: 493 KKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPF 531 K +W+ ++ L+SG D I+A ++I +ER + I+F++ + Sbjct: 50 KNDWDSIIPNLVSGNYDTIIAGMSITDERDEVIDFTQNY 88 >4YMX-A nrPDB Length = 260 Score = 35.8 bits (81), Expect = 0.081, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 32/58 (55%) Query: 495 EWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 ++ G++ L +G+ DM++A +T ER + ++FS + ++VK + P S D Sbjct: 87 DFKGLIPALQAGRVDMVIAGMTPTAERKKSVDFSDLYYDSRQVVVVKNDSPISKFDDL 144 >4G4P-A nrPDB Length = 244 Score = 35.4 bits (80), Expect = 0.12, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 17/88 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G VDLL +A++ +F EV L G ++ + + S Q D ++A Sbjct: 47 GIDVDLLDAIAKDQDF--EVDLKPLG---------------FDSAVQAIQSKQIDGMIAG 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKK 542 ++I +ER + +FS P+ GL + VKK Sbjct: 90 MSITDERKKSFDFSDPYFDSGLQLAVKK 117 >5JOS-A nrPDB Length = 247 Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 28/48 (58%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 W +M +L + + D+ + +T+ ER + +FS P+ G T LV+KE Sbjct: 71 WPTLMSDLQADKFDIAMGGVTVTPERQKKADFSDPYMTFGKTPLVRKE 118 >2IEE-A nrPDB Length = 271 Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 26/47 (55%) Query: 497 NGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 +GM+ + SGQ D + + +R + FS P+KY T +V+K+ Sbjct: 73 DGMLTAVNSGQVDAAANDIDVTKDREEKFAFSTPYKYSYGTAIVRKD 119 >3VV5-A nrPDB Length = 260 Score = 34.7 bits (78), Expect = 0.21, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 32/57 (56%) Query: 494 KEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLD 550 + ++ ++ +L G+ D ++A I ERA+ ++F+ P G I+ +K PR+ D Sbjct: 82 QSFDTLLIQLNQGRFDFVIASHGITEERARAVDFTNPHYCTGGVIVSRKGGPRTAKD 138 >5EYF-A nrPDB Length = 245 Score = 34.7 bits (78), Expect = 0.22, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 25/40 (62%) Query: 503 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 L +G D I+A +TI +ER + ++FS + G +LVKK Sbjct: 74 LKNGNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKK 113 >4H5F-A nrPDB Length = 243 Score = 33.1 bits (74), Expect = 0.50, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 29/47 (61%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 ++ ++ L +G+AD+ VA ++ +ER + +FS P+ ++ LV K Sbjct: 63 FDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVHK 109 >3OJO-A nrPDB Length = 431 Score = 32.7 bits (73), Expect = 0.79, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 530 PFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV 571 PF +G TI+V+ I T+D F++P L +G +++V Sbjct: 117 PFLKKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLV 158 >4F11-A nrPDB Length = 433 Score = 32.3 bits (72), Expect = 0.86, Method: Compositional matrix adjust. Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%) Query: 127 IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLL-- 184 + +DK + F RTVP + ++++ + W V + D + L +L Sbjct: 121 VLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYG 180 Query: 185 EEKESKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAG 244 E+ E + +P T + + K + R+I+ ++ A V+ A +M G+ Sbjct: 181 EDIEISDTESFSNDPCTS-----VKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSK 235 Query: 245 YVWLV 249 Y W++ Sbjct: 236 YQWII 240 >6CCZ-A nrPDB Length = 455 Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 24/45 (53%) Query: 647 ANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYF 691 AN A + + +P +RI G++ P + S F+ A + S IYF Sbjct: 106 ANFAVYTAILKPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYF 150 >4I62-A nrPDB Length = 269 Score = 31.6 bits (70), Expect = 1.8, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 30/47 (63%) Query: 496 WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK 542 ++ ++ + SG+AD+ ++ ++ +ER++ +FS P+ ++VKK Sbjct: 90 FDNVLASVQSGKADLAISGVSKTDERSKVFDFSTPYYTAKNKLIVKK 136 >2HOR-A nrPDB Length = 427 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 31/186 (16%) Query: 574 MLYLLDRFSPFGRFKVNSEEEEEDALTLS-------SAMWFSWGVLLNSGI--------- 617 M+Y ++P ++K +ED L + S F W ++ + + Sbjct: 226 MVYYWPHYTPI-KYKA-----DEDILLFTMSKFTGHSGSRFGWALIKDESVYNNLLNYMT 279 Query: 618 --GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD 675 EG PR R L ++ AM+ T + ER +N L + SD Sbjct: 280 KNTEGTPRETQLRSLKVLKEVVAMVKTQKGTMRDLNTFGFKKLRERW--VNITALLDQSD 337 Query: 676 KFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLE 735 +F Y + QS YFRR S Y + K +E + Q ++ +++ + Sbjct: 338 RFSYQELPQSEYCNYFRRMRPPSPSYAWV-KCEWEEDKDCYQTFQNGRINT----QNGVG 392 Query: 736 FEASQK 741 FEAS + Sbjct: 393 FEASSR 398 >5ORE-A nrPDB Length = 263 Score = 30.8 bits (68), Expect = 2.9, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 23/38 (60%) Query: 494 KEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPF 531 + W+G+M L + D I+A +++ +R + I FS P+ Sbjct: 50 QNWDGIMPSLTGKKYDAIMAAMSVTPKRQEVIGFSIPY 87 >3TQL-A nrPDB Length = 227 Score = 30.4 bits (67), Expect = 3.8, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 40/96 (41%), Gaps = 12/96 (12%) Query: 462 IKLAREMNFTYEVHLVADGK---FGTQ---------ERVNNSNKKEWNGMMGELLSGQAD 509 IK A E + V++ G+ FG + V + + W+ ++ L G+ D Sbjct: 4 IKFATEATYPPYVYMGPSGQVEGFGADIVKAVCKQMQAVCTISNQPWDSLIPSLKLGKFD 63 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 + + I R + ++F+ P+ ++ + K P Sbjct: 64 ALFGGMNITTARQKEVDFTDPYYTNSVSFIADKNTP 99 >4CHV-A nrPDB Length = 361 Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 11/68 (16%) Query: 563 LVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAP 622 L G+ + VA+ Y+++R + + E ++ AMW++ L +G G+ P Sbjct: 135 LFGVVLFAVALAAYVIER-----------DIQPEKFGSIPQAMWWAVVTLSTTGYGDTIP 183 Query: 623 RSFSARIL 630 +SF+ R+L Sbjct: 184 QSFAGRVL 191 >3KTD-A nrPDB Length = 341 Score = 30.0 bits (66), Expect = 5.1, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 26/48 (54%) Query: 171 HEGRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLEAKELEARV 218 +E R+ Q++ + + + + VL+ PGT N L+ A+ L AR+ Sbjct: 291 YEARSGQRRAKESVSPTITSSRPVLRLHPGTPNWEKQLIHAETLGARI 338 >5A1S-A nrPDB Length = 448 Score = 29.3 bits (64), Expect = 8.7, Method: Compositional matrix adjust. Identities = 12/20 (60%), Positives = 14/20 (70%) Query: 235 AAMLDMTGAGYVWLVGEREI 254 AA+LDM G Y WL GE E+ Sbjct: 227 AALLDMVGKKYTWLSGEGEL 246 >4CBI-A nrPDB Length = 516 Score = 29.3 bits (64), Expect = 8.9, Method: Compositional matrix adjust. Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 76 LSVCEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHL 135 L + +L+ S+ + V + A TDH P ++Y + ++PV+ R +D + Sbjct: 395 LEILNNLLISEELPMAVKNIMARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDTYDNY 454 Query: 136 SFLRT------VPPYSH 146 +FL VPPY + Sbjct: 455 TFLNARKLGDDVPPYVY 471 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5UOW-A nrPDB 1128 0.0 5FXI-A nrPDB 1104 0.0 5KUF-A nrPDB 859 0.0 5UP2-B nrPDB 854 0.0 4PE5-B nrPDB 828 0.0 5IPR-B nrPDB 827 0.0 6IRA-D nrPDB 826 0.0 6QKC-A nrPDB 785 0.0 5IDF-B nrPDB 711 0.0 4U1Y-A nrPDB 697 0.0 5UN1-G nrPDB 656 0.0 5UN1-B nrPDB 554 e-158 5KUH-A nrPDB 448 e-126 5L2E-A nrPDB 387 e-108 1YAE-A nrPDB 261 1e-69 5I2K-B nrPDB 225 1e-58 2RC9-A nrPDB 191 9e-49 2RCB-A nrPDB 185 8e-47 5H8N-A nrPDB 184 2e-46 3OEK-A nrPDB 182 6e-46 4MF3-A nrPDB 178 1e-44 2XXT-A nrPDB 178 1e-44 3DP4-A nrPDB 176 4e-44 3FAT-A nrPDB 174 2e-43 5O9A-A nrPDB 173 3e-43 5IKB-A nrPDB 169 6e-42 4IGR-A nrPDB 168 1e-41 5X2M-A nrPDB 159 6e-39 5K5S-A nrPDB 157 2e-38 5FBH-B nrPDB 157 2e-38 5EHM-A nrPDB 156 3e-38 5DT6-A nrPDB 149 4e-36 2E4V-A nrPDB 144 2e-34 5CNM-A nrPDB 143 4e-34 5CNI-A nrPDB 142 8e-34 5KZQ-A nrPDB 141 1e-33 4WXJ-A nrPDB 139 5e-33 5CC2-A nrPDB 138 1e-32 6BT5-A nrPDB 130 3e-30 5C5C-A nrPDB 123 3e-28 5X2N-B nrPDB 116 4e-26 4YKP-A nrPDB 115 9e-26 4ZDM-A nrPDB 108 1e-23 5TUJ-C nrPDB 94 3e-19 4ZV2-A nrPDB 85 1e-16 4IO3-A nrPDB 84 2e-16 4F3S-A nrPDB 59 9e-09 Sequences not found previously or not previously below threshold: 1ISS-A nrPDB 104 2e-22 6N4Y-A nrPDB 102 6e-22 6N4X-A nrPDB 102 6e-22 3LMK-A nrPDB 102 8e-22 4MS4-A nrPDB 78 1e-14 4PSH-A nrPDB 75 2e-13 4F3P-A nrPDB 74 4e-13 2Q2A-A nrPDB 72 1e-12 1GGG-A nrPDB 71 2e-12 5JOS-A nrPDB 71 2e-12 3K4U-A nrPDB 71 3e-12 2PYY-A nrPDB 70 4e-12 4F11-A nrPDB 70 6e-12 4YMX-A nrPDB 68 1e-11 4ZEF-A nrPDB 65 1e-10 1YK0-A nrPDB 64 2e-10 5EYF-A nrPDB 62 1e-09 4G4P-A nrPDB 62 1e-09 4H5F-A nrPDB 57 3e-08 5OTA-A nrPDB 54 2e-07 4I62-A nrPDB 54 2e-07 3TQL-A nrPDB 52 7e-07 3A3K-A nrPDB 52 8e-07 6FXG-A nrPDB 52 1e-06 4KPT-A nrPDB 52 2e-06 5HPQ-A nrPDB 51 3e-06 5LOM-A nrPDB 49 7e-06 4OEN-A nrPDB 49 8e-06 3I6V-A nrPDB 49 9e-06 3VV5-A nrPDB 49 1e-05 5ORE-A nrPDB 48 1e-05 2IEE-A nrPDB 46 8e-05 2Y7I-A nrPDB 45 1e-04 4KQP-A nrPDB 45 1e-04 4MLC-A nrPDB 43 6e-04 5OWF-A nrPDB 43 6e-04 3IP9-A nrPDB 43 7e-04 4GNR-A nrPDB 43 7e-04 1HSL-A nrPDB 41 0.003 1IIT-A nrPDB 39 0.007 4Q0C-A nrPDB 39 0.007 3DEL-B nrPDB 37 0.052 2Q88-A nrPDB 35 0.15 2A79-B nrPDB 33 0.74 4JTA-B nrPDB 32 0.96 4CHV-A nrPDB 32 1.7 6G72-J nrPDB 30 3.9 5NTF-A nrPDB 30 5.6 >5UOW-A nrPDB Length = 814 Score = 1128 bits (2918), Expect = 0.0, Method: Composition-based stats. Identities = 796/814 (97%), Positives = 800/814 (98%) Query: 23 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 82 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL Sbjct: 1 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 60 Query: 83 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 142 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP Sbjct: 61 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 120 Query: 143 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK 202 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK Sbjct: 121 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK 180 Query: 203 NLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYA 262 NLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYA Sbjct: 181 NLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYA 240 Query: 263 PDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFK 322 PDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEME ITDPPRGCVGNTNIWKTGPLFK Sbjct: 241 PDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMEQITDPPRGCVGNTNIWKTGPLFK 300 Query: 323 RVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWP 382 RVLMSSKYPDGVTGRIEFNEDGDRKFA YSIMNLQNRKLVQVGIF+GSYIIQNDRKIIWP Sbjct: 301 RVLMSSKYPDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWP 360 Query: 383 GGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNET 442 GGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGP+ET Sbjct: 361 GGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDET 420 Query: 443 IPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGE 502 IPGRPTVPQCCYGFCVDLLIKLAREM+FTYEVHLVADGKFGTQERVNNSN WNGMMGE Sbjct: 421 IPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGE 480 Query: 503 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWL 562 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWL Sbjct: 481 LLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWL 540 Query: 563 LVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAP 622 LVGLSVHVVAVMLYLLDRFSPFGRFKVNS EEDALTLSSAMWFSW VLLNSG+GEGAP Sbjct: 541 LVGLSVHVVAVMLYLLDRFSPFGRFKVNSAAAEEDALTLSSAMWFSWRVLLNSGLGEGAP 600 Query: 623 RSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATV 682 RSFSARILGMVWA FAMIIVASYTANLAAFLVL RPEERITGINDPRLRNPSDKFIYATV Sbjct: 601 RSFSARILGMVWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATV 660 Query: 683 KQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKC 742 KQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQ C Sbjct: 661 KQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQDC 720 Query: 743 DLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSNA 802 DLVTTGELFFRSGFGIGMRKDSPWKQ VSLNILKSHENGFMEELDKTWVRYQECDSRSNA Sbjct: 721 DLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNA 780 Query: 803 PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYK 836 PATLTFENMAGVF LVAGGIVAGIFLIFIEIAYK Sbjct: 781 PATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814 >5FXI-A nrPDB Length = 846 Score = 1104 bits (2856), Expect = 0.0, Method: Composition-based stats. Identities = 753/846 (89%), Positives = 793/846 (93%), Gaps = 23/846 (2%) Query: 23 DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 82 DPKIVNIGAVLST+KHEQ+FREAVNQANKRH + KIQL ATSVTH+PNAIQMALSVCEDL Sbjct: 1 DPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLQATSVTHKPNAIQMALSVCEDL 60 Query: 83 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 142 ISSQVYAILVSHPP P DH TPTP+SYTAGFYRIPV+GLTTRMSIYSDKSIHLSFLRTVP Sbjct: 61 ISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVP 120 Query: 143 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESK------------ 190 PYSHQ+ VWFEMMR++NWNH+IL+VSDDHEGRAAQK+LETLLEE+ESK Sbjct: 121 PYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKSKKRNYENLDQL 180 Query: 191 ---------ADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMT 241 A+KVLQF+PGTKN+TALL+EA+ELEARVIILSASEDDA VY++AAMLDMT Sbjct: 181 SYDNKRGPKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLDMT 240 Query: 242 GAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENI 301 G+GYVWLVGEREISG+ALRYAPDGIIGLQLINGKNESAHISDAV VVAQA+HEL E ENI Sbjct: 241 GSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENI 300 Query: 302 TDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKL 361 TDPPRGCVGNTNIWKTGPLFKRVLMSSKY DGVTGR+EFNEDGDRKFA YSIMNLQNRKL Sbjct: 301 TDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKL 360 Query: 362 VQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCR 421 VQVGI+NG+++I NDRKIIWPGGETE+P+GYQMSTRLKIVTIHQEPFVYV+PT SDGTC+ Sbjct: 361 VQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCK 420 Query: 422 EEYTINGDPIKKVICNGPNETIPGRP--TVPQCCYGFCVDLLIKLAREMNFTYEVHLVAD 479 EE+T+NGDP+KKVIC GPN+T PG P TVPQCCYGFC+DLLIKLAR M FTYEVHLVAD Sbjct: 421 EEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMQFTYEVHLVAD 480 Query: 480 GKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL 539 GKFGTQERV NSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL Sbjct: 481 GKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL 540 Query: 540 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDAL 599 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNS+ E DAL Sbjct: 541 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSQSESTDAL 600 Query: 600 TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPE 659 TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPE Sbjct: 601 TLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPE 660 Query: 660 ERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAV 719 ERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAV Sbjct: 661 ERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAV 720 Query: 720 RDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHE 779 RDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQ VSL+ILKSHE Sbjct: 721 RDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHE 780 Query: 780 NGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 839 NGFME+LDKTWVRYQECDSRSNAPATLT ENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK Sbjct: 781 NGFMEDLDKTWVRYQECDSRSNAPATLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK 840 Query: 840 DARRKQ 845 DA Q Sbjct: 841 DANGAQ 846 >5KUF-A nrPDB Length = 877 Score = 859 bits (2218), Expect = 0.0, Method: Composition-based stats. Identities = 219/900 (24%), Positives = 398/900 (44%), Gaps = 110/900 (12%) Query: 26 IVNIGAVL------STKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVC 79 ++ G + E FR AVN N+ + L T++T+ I + S Sbjct: 4 VLRFGGIFEYVESGPMGAEELAFRFAVNTINRN----RTLLPNTTLTYDTQKINLYDSFE 59 Query: 80 EDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLR 139 + ++ V+ P+ + + +P I + + +K ++ Sbjct: 60 ASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKD--SFYVS 117 Query: 140 TVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEP 199 P +S + ++++ F W V ++ D Q+ ++ + + K+ Q Sbjct: 118 LYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIK--APSRYNLRLKIRQLPA 175 Query: 200 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISG--- 256 TK+ LL E K + +I S + A + K A + M Y ++ ++ Sbjct: 176 DTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDV 235 Query: 257 SALRYAPDGIIGLQLINGKN--------------------------------ESAHISDA 284 RY+ + G +++N +N ++A + DA Sbjct: 236 EPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDA 295 Query: 285 VAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNE-D 343 V VV+ A+ + +M T C W+ G F ++ + +G+TGRI FN+ + Sbjct: 296 VHVVSVAVQQFPQM---TVSSLQC-NRHKPWRFGTRFMSLIKEAH-WEGLTGRITFNKTN 350 Query: 344 GDRKFANYSIMNLQNRKLVQVGIFNG-SYIIQNDRKIIWPGGETERPQGYQMSTRLKIVT 402 G R + +++L+ L ++G ++ S + + + P T+ L + T Sbjct: 351 GLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRS----LIVTT 406 Query: 403 IHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLI 462 I +EP+V + + + + G+C+DLL Sbjct: 407 ILEEPYVLFKKSDKPLYGNDRFE-----------------------------GYCIDLLR 437 Query: 463 KLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERA 522 +L+ + FTYE+ LV DGK+G Q+ VN +WNGM+ EL+ +AD+ VAPLTI R Sbjct: 438 ELSTILGFTYEIRLVEDGKYGAQDDVN----GQWNGMVRELIDHKADLAVAPLTITYVRE 493 Query: 523 QYIEFSKPFKYQGLTILVKKEIPR-STLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRF 581 + I+FSKPF G++IL +K + SF+ P +W+ V L+ V+V+L+++ RF Sbjct: 494 KVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLAYLGVSVVLFVIARF 553 Query: 582 SPFGRFKVNSEEEEEDA----LTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGF 637 SP+ + + + D TL ++ WF G L+ G E P++ S RI+G +W F Sbjct: 554 SPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQG-SELMPKALSTRIVGGIWWFF 612 Query: 638 AMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--V 695 +II++SYTANLAAFL ++R E I +D + K Y V+ S +F++ Sbjct: 613 TLIIISSYTANLAAFLTVERMESPIDSADDLAKQT---KIEYGAVEDGSTMTFFKKSKIS 669 Query: 696 ELSTMYRHMEKHN----YESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELF 751 M+ M +S+ E IQ V + +A + +S +EF + C+L G L Sbjct: 670 TYDKMWAFMSSRRQSVLVKSSEEGIQRVLTSD-YALLMESTTIEFVTQRNCNLTQIGGLI 728 Query: 752 FRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQEC-DSRSNAPATLTFEN 810 G+G+G SP++ +++ IL+ E G + + + W R C + S + L +N Sbjct: 729 DSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQN 788 Query: 811 MAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEP 870 + G+F+++A G+V +F+ E YK K+A+ ++ A V R +L+ ++ + +P Sbjct: 789 IGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKP 848 >5UP2-B nrPDB Length = 831 Score = 854 bits (2206), Expect = 0.0, Method: Composition-based stats. Identities = 227/859 (26%), Positives = 420/859 (48%), Gaps = 61/859 (7%) Query: 9 LAVLFLFSFARAG-------CDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLN 61 + VL L++F AG ++NI +L ++ I + R + +N Sbjct: 3 MFVLLLYTFLYAGDLGHGAEKSFPVLNIAVILGRTRY--ITERDIRSLWTRDMSLDFDVN 60 Query: 62 A-TSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPI-SYTAGFYRIPVI 119 T + + + + VC+ + ++++ ++ TD I + + IP++ Sbjct: 61 VVTLLVQQTDPKSIITHVCDLMSGTKIHGVVFGDD---TDQEAIAQILDFVSSQTFIPIL 117 Query: 120 GLTTRMS-IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG-RAAQ 177 G+ S I +DK +F + QA V +M ++W HV +++ + G R Sbjct: 118 GIHGGSSMIMADKDEMSTFFQFGASIKQQATVMLNIMEEYDW-HVFSVITSNFPGYRDFI 176 Query: 178 KKLETLLEEKESKADKVLQFEPGTKNLT-ALLLEAKELEARVIILSASEDDATAVYKSAA 236 ++T ++ + T L + K++ + VI+L S+D+AT +++ A Sbjct: 177 SFIKTTVDNSFVGWEVQNYITLDTSYTDAQTLTQLKKIHSSVILLYCSKDEATYIFEEAR 236 Query: 237 MLDMTGAGYVWLVGEREISGSAL--RYAPDGIIGLQLINGKN-ESAHISDAVAVVAQAIH 293 L + G G+VW+V + + P G++ + + A + D + ++ A Sbjct: 237 SLGLMGYGFVWIVPSLVTGNTDIIPYEFPSGLVSVSYDDWDYGIEARVRDGLGIITTAAS 296 Query: 294 ELFEMENITDPPRGCVGNTNIWKTGPLF-KRVLMSSKYPDGVTGRIEFNEDGDRKFANYS 352 + E ++ + N PL M + DG + F EDG + Sbjct: 297 AMLEKHSVIPEAKTSCYGQNERNDPPLHTLHNFMINVTWDG--KDLSFTEDGYQANPKLV 354 Query: 353 IMNLQ-NRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYV 411 ++ L R+ +VG + + N + +WP +++ L IVT+ + PFV V Sbjct: 355 VLLLNMEREWEKVGKWEAKSL--NMKYPVWPRIDSDHDD-----NHLSIVTLEEAPFVIV 407 Query: 412 RPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNF 470 GTC N P +K N T G +V +CC GFC+D+L KL++ + F Sbjct: 408 ENIDYLTGTCVR----NTVPCRKYF-RLANSTTEGT-SVKKCCKGFCIDILKKLSKTVKF 461 Query: 471 TYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKP 530 TY+++LV +GK G + + WNGM+GE++ +A M V LTIN ER+ ++FS P Sbjct: 462 TYDLYLVTNGKHGKKIK------NVWNGMIGEVVYKRAVMAVGSLTINEERSVAVDFSVP 515 Query: 531 FKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVM-LYLLDRFSPFG--RF 587 F G++++V + + +F++PF +++W+++ + + +V+ M +++ + FSP G R Sbjct: 516 FVETGISVMVSRSAGTVSPSAFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFSPVGYNRN 575 Query: 588 KVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTA 647 ++ + T+ A+W WG++ N+ + P+ +++I+ +WA FA+I +ASYTA Sbjct: 576 LAQGKDPHGPSFTIGKAVWLLWGLVFNNSLPVQNPKGTTSKIIVSIWAFFAVIFLASYTA 635 Query: 648 NLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVELSTMYRHM 704 NLAAF++ R +++TG++D + + P D F + TV Q S + R M+++M Sbjct: 636 NLAAFMIQRRFVDQVTGLSDNKFQRPHDYSPPFRFGTVPQGSTERNIRNN--YPDMHQYM 693 Query: 705 EKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQK--CDLVTT--GELFFRSGFGIGM 760 K + + +A+ +++ KL AFI+D+AVL + A + C LVT G +F +G+GI + Sbjct: 694 VKFHQKGVQDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIAL 753 Query: 761 RKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFENMAGVFMLV 818 +K S WK+ + L +L+ +G MEEL+K W+ C + N + L +NMAGVF ++ Sbjct: 754 QKGSRWKRPIDLALLQFVGDGEMEELEKLWLT-GICHTEKNEVMSSQLDIDNMAGVFYML 812 Query: 819 AGGIVAG-IFLIFIEIAYK 836 A + I ++ + YK Sbjct: 813 AAAMALSLITFVWEHLFYK 831 >4PE5-B nrPDB Length = 820 Score = 828 bits (2138), Expect = 0.0, Method: Composition-based stats. Identities = 221/849 (26%), Positives = 415/849 (48%), Gaps = 70/849 (8%) Query: 19 RAGCDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFT--RKIQLNATSVTHRPNAIQMAL 76 R+ P + I +L E ++A + + H + +++L A + T + + Sbjct: 1 RSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNET---DPKSIIT 57 Query: 77 SVCEDLISSQVYAILVSHPPAPTDHLTPTPI-SYTAGFYRIPVIGLTTRMS-IYSDKSIH 134 +C+ + ++ ++ + TD I + + P++G+ S I +DK Sbjct: 58 RICDLMSDRKIQGVVFADD---TDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDES 114 Query: 135 LSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG-RAAQKKLETLLEEKESKADK 193 F + P QA V +M ++W ++ IV+ G + K+ + +E + Sbjct: 115 SMFFQFGPSIEQQASVMLNIMEEYDW-YIFSIVTTYFPGYQDFVNKIRSTIENSFVGWEL 173 Query: 194 ------VLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVW 247 + + G + L K+L++ +I+L ++++AT +++ A + +TG GY W Sbjct: 174 EEVLLLDMSLDDGDCKIQNQL---KKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTW 230 Query: 248 LVGEREISGSAL--RYAPDGIIGLQLINGKN-ESAHISDAVAVVAQAIHELFEMENITDP 304 +V + P G+I + A + D +A++ A ++ + Sbjct: 231 IVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPE 290 Query: 305 PRGCVGNTNIWK--TGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNL-QNRKL 361 P+ NT+ + + R L++ + +G + F+EDG + I+ L + RK Sbjct: 291 PKSSCYNTHEKRIYQSNMLNRYLINVTF-EGR--DLSFSEDGYQMHPKLVIILLNKERKW 347 Query: 362 VQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTS-DGTC 420 +VG + + + +WP + L IVT+ + PFV V GTC Sbjct: 348 ERVGKWKDKSL--QMKYYVWPRMTQDD--------HLSIVTLEEAPFVIVESVDPLSGTC 397 Query: 421 REEYTINGDPI-KKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVAD 479 N P K++I + PG + +CC GFC+D+L K+++ + FTY+++LV + Sbjct: 398 MR----NTVPCQKRIISENKTDEEPG--YIKKCCKGFCIDILKKISKSVKFTYDLYLVTN 451 Query: 480 GKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTIL 539 GK G + WNGM+GE++ +A M V LTIN ER++ ++FS PF G++++ Sbjct: 452 GKHGKK------INGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVM 505 Query: 540 VKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVMLYLLDRFSPFG--RFKVNSEEEEE 596 V + + +F++PF + +W+++ + + +V AV +++ + FSP G R + E Sbjct: 506 VSRSNGTVSPSAFLEPFSACVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRSLADGREPGG 565 Query: 597 DALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLD 656 + T+ A+W WG++ N+ + P+ +++I+ VWA FA+I +ASYTANLAAF++ + Sbjct: 566 PSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQE 625 Query: 657 RPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAA 713 ++++G++D + + P+D F + TV S + R + M+ +M K N Sbjct: 626 EYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN--YAEMHAYMGKFNQRGVD 683 Query: 714 EAIQAVRDNKLHAFIWDSAVLEFEASQK--CDLVTT--GELFFRSGFGIGMRKDSPWKQN 769 +A+ +++ KL AFI+D+AVL + A + C LVT G++F +G+GI ++KDS WK+ Sbjct: 684 DALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQ 743 Query: 770 VSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFENMAGVFMLVAGGIVAGIF 827 V L IL+ +G MEEL+ W+ C + N + L +NMAGVF ++ + + Sbjct: 744 VDLAILQLFGDGEMEELEALWLT-GICHNEKNEVMSSQLDCDNMAGVFYMLGAAMALSLI 802 Query: 828 LIF-IEIAY 835 + Y Sbjct: 803 TFISEHLFY 811 >5IPR-B nrPDB Length = 825 Score = 827 bits (2137), Expect = 0.0, Method: Composition-based stats. Identities = 224/850 (26%), Positives = 415/850 (48%), Gaps = 64/850 (7%) Query: 11 VLFLFSFARAGCDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFT--RKIQLNATSVTHR 68 ++ +S A A P ++I +L E ++ + + H +++L Sbjct: 15 IILFYSRAYAQKHPN-MDIAVILVGTTEEVAIKDVHEKDDFHHLPVTPRVELVTM---QE 70 Query: 69 PNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPI-SYTAGFYRIPVIGLTTRMS- 126 + + +C+ + +V ++ TD I + + P++G+ S Sbjct: 71 SDPKSIITRICDLMSDKKVQGVVFGDD---TDQEAIAQILDFISVQTLTPILGIHGGSSM 127 Query: 127 IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEG-RAAQKKLETLLE 185 I +DK F + P QA V +M ++W ++ IV+ G + + K+ + +E Sbjct: 128 IMADKEEASMFFQFGPSIEQQASVMLNIMEEYDW-YIFSIVTTYFPGYQDFENKVRSTIE 186 Query: 186 EKESKAD--KVLQFEPGTKNLTALLL-EAKELEARVIILSASEDDATAVYKSAAMLDMTG 242 + +V+ + ++ + + + K+L++ VI+L ++++AT +++ A + +TG Sbjct: 187 NSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEVAHSVGLTG 246 Query: 243 AGYVWLVGEREISGSAL--RYAPDGIIGLQLINGKNE-SAHISDAVAVVAQAIHELFEME 299 G+ W+V + P G+I + + A + D +A++ A + Sbjct: 247 YGFTWIVPSLVAGDTDTVPDEFPTGLISVSYDEWDYDLPARVRDGIAIITTAASTMLSEH 306 Query: 300 NITDPPRGCVGNTNIWKT--GPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNL- 356 N + N + + KR L++ + +G + F+EDG + I+ L Sbjct: 307 NSIPQSKSSCNNIQESRVYEAHMLKRYLINVTF-EGR--DLSFSEDGYQMHPKLVIILLN 363 Query: 357 QNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTS 416 Q RK +VG + + +WP + L IVT+ + PFV V Sbjct: 364 QERKWERVGKYKDRSL------KMWPVFDLYPNSEEHKDEHLSIVTLEEAPFVIVEDVDP 417 Query: 417 -DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVH 475 GTC N P +K I N T G + +CC GFC+D+L K+A+ + FTY+++ Sbjct: 418 LSGTCMR----NTVPCRKQI-RPENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDLY 472 Query: 476 LVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQG 535 LV +GK G + WNGM+GE+++ +A M V LTIN ER++ ++FS PF G Sbjct: 473 LVTNGKHGKK------INGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETG 526 Query: 536 LTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVMLYLLDRFSPFGRFKVNSEEE 594 ++++V + + +F++PF + +W+++ + + +V AV +++ + FSP G Sbjct: 527 ISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGY-------- 578 Query: 595 EEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLV 654 + T+ A+W WG++ N+ + P+ +++I+ VWA FA+I +ASYTANLAAF++ Sbjct: 579 NGPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMI 638 Query: 655 LDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYES 711 R ++++G++D + + P+D F + TV S + R M+ +M K N S Sbjct: 639 QRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNN--YLEMHSYMVKFNQRS 696 Query: 712 AAEAIQAVRDNKLHAFIWDSAVLEFEASQK--CDLVTT--GELFFRSGFGIGMRKDSPWK 767 +A+ +++ KL AFI+D+AVL + A + C LVT G++F +G+GI ++KDS WK Sbjct: 697 VQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWK 756 Query: 768 QNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFENMAGVFMLVAGGIVAG 825 + V L IL+ +G MEEL+ W+ C + N + L +NMAGVF ++A + Sbjct: 757 RQVDLAILQLFGDGEMEELEALWLT-GICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALS 815 Query: 826 IFLIFIEIAY 835 + +E + Sbjct: 816 LITFIMEHLF 825 >6IRA-D nrPDB Length = 853 Score = 826 bits (2134), Expect = 0.0, Method: Composition-based stats. Identities = 229/876 (26%), Positives = 425/876 (48%), Gaps = 58/876 (6%) Query: 1 MGTMRLFLLAVLFLFS----FARAGCDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTR 56 +G L +L L ++ A A P +NI +L + + Sbjct: 4 VGYWTLLVLPALLVWRGPAPSAAAEKGPPALNIAVMLGHSHD--VTERELRTLWGPEQAA 61 Query: 57 KIQL---NATSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTP-ISYTAG 112 + L + +R + + VC+ + ++++ ++ TD + + + Sbjct: 62 GLPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDD---TDQEAVAQMLDFISS 118 Query: 113 FYRIPVIGLTTRMS-IYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDH 171 +P++G+ S I +DK +F + QA V ++M+ ++W HV +V+ Sbjct: 119 HTFVPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDW-HVFSLVTTIF 177 Query: 172 EG-RAAQKKLETLLEEKESKAD--KVLQFEPGTKNLTALLLEAKELEARVIILSASEDDA 228 G R ++T ++ D V+ + ++ + + K++ + VI+L S+D+A Sbjct: 178 PGYREFISFVKTTVDNSFVGWDMQNVITLDTSFEDAKTQV-QLKKIHSSVILLYCSKDEA 236 Query: 229 TAVYKSAAMLDMTGAGYVWLVGEREISGSAL--RYAPDGIIGLQLINGKNE-SAHISDAV 285 + A L +TG + W+V + L + P G+I + + A + D + Sbjct: 237 VLILSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGI 296 Query: 286 AVVAQAIHELFEM-ENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDG 344 ++ A + E I + C G + M + DG + F E+G Sbjct: 297 GILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHTLHPFMVNVTWDG--KDLSFTEEG 354 Query: 345 DRKFANYSIMNL-QNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTI 403 + ++ L ++R+ +VG + + + R +WP ++ L IVT+ Sbjct: 355 YQVHPRLVVIVLNKDREWEKVGKWENHTL--SLRHAVWPRYKSFSDCE-PDDNHLSIVTL 411 Query: 404 HQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLI 462 + PFV V TC N P +K + N + V +CC GFC+D+L Sbjct: 412 EEAPFVIVEDIDPLTETCVR----NTVPCRKFVK--INNSTNEGMNVKKCCKGFCIDILK 465 Query: 463 KLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERA 522 KL+R + FTY+++LV +GK G ++VNN WNGM+GE++ +A M V LTIN ER+ Sbjct: 466 KLSRTVKFTYDLYLVTNGKHG--KKVNNV----WNGMIGEVVYQRAVMAVGSLTINEERS 519 Query: 523 QYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-AVMLYLLDRF 581 + ++FS PF G++++V + + +F++PF +++W+++ + + +V A+ +++ + F Sbjct: 520 EVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYF 579 Query: 582 SPFG--RFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAM 639 SP G R + + T+ A+W WG++ N+ + P+ +++I+ VWA FA+ Sbjct: 580 SPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAV 639 Query: 640 IIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDIYFRRQVE 696 I +ASYTANLAAF++ R +++TG++D + + P D F + TV S + R Sbjct: 640 IFLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN-- 697 Query: 697 LSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQK--CDLVTT--GELFF 752 M+++M K N + +A+ +++ KL AFI+D+AVL ++A + C LVT G +F Sbjct: 698 YPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFA 757 Query: 753 RSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--APATLTFEN 810 +G+GI ++K SPWK+ + L +L+ +G MEEL+ W+ C + N + L +N Sbjct: 758 TTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLT-GICHNEKNEVMSSQLDIDN 816 Query: 811 MAGVFMLVAGGIVAG-IFLIFIEIAYKRHKDARRKQ 845 MAGVF ++A + I I+ + YK +A+R + Sbjct: 817 MAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMK 852 >6QKC-A nrPDB Length = 915 Score = 785 bits (2028), Expect = 0.0, Method: Composition-based stats. Identities = 219/886 (24%), Positives = 399/886 (45%), Gaps = 131/886 (14%) Query: 24 PKIVNIGAVLSTKKHEQ--IFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCED 81 P + IG + ++ ++ FR A++Q + K+ L + + ++ +M C Sbjct: 30 PNNIQIGGLFPNQQSQEHAAFRFALSQLTE---PPKL-LPQIDIVNISDSFEMTYRFCSQ 85 Query: 82 LISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTV 141 S VYAI + + LT S+ + V +T + + F+ + Sbjct: 86 F-SKGVYAIFGFYERRTVNMLT----SFCGALH---VCFITPSFPVDTSNQ----FVLQL 133 Query: 142 PPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE--KESKADKVLQFEP 199 P +AL+ ++ + W + I D Q+ L+T E+ + + + + E Sbjct: 134 RPELQEALI--SIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEE 191 Query: 200 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISG 256 G + L L + K R++++ + A+ L+ G GY +++ G +I Sbjct: 192 GYRMLFQDLEKKK---ERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL 248 Query: 257 SALRYAPDGIIGLQLIN----------------------------GKNESAHISDAVAVV 288 + + + + G QL+N K SA D V V+ Sbjct: 249 NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSALTYDGVKVM 308 Query: 289 AQAIHELFEMENITDPPRG----CVGNTN-IWKTGPLFKRVLMSSKYPDGVTGRIEFNED 343 A+A L + I RG C+ N W G +R L ++ +G+TG ++FNE Sbjct: 309 AEAFQSL-RRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEK 366 Query: 344 GDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLK---I 400 G R ++ +++ + ++G +N D K + P + G S + + + Sbjct: 367 GRRTNYTLHVIEMKHDGIRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIV 419 Query: 401 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDL 460 TI ++P+V ++ + + Y G+CV+L Sbjct: 420 TTILEDPYVMLKKNANQFEGNDRYE-----------------------------GYCVEL 450 Query: 461 LIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNE 520 ++A+ + ++Y + +V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI Sbjct: 451 AAEIAKHVGYSYRLEIVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLV 506 Query: 521 RAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 579 R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+ Sbjct: 507 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 566 Query: 580 RFSPFGRFKVNSEEE-------EEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGM 632 RFSP+ EE + + + +++WFS G + G + +PRS S RI+G Sbjct: 567 RFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGG 625 Query: 633 VWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFR 692 VW F +II++SYTANLAAFL ++R I D + + Y T++ S +FR Sbjct: 626 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFR 682 Query: 693 RQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDL 744 R M+ +M+ + E + VR +K +A++ +S + E+ E + CD Sbjct: 683 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDT 742 Query: 745 VTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD-KTWVRYQECDSRSNAP 803 + G G+GI K S + V+L +LK E G +++L K W EC S+ + Sbjct: 743 MKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGS 802 Query: 804 ----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQ 845 + L+ N+AGVF ++ GG+ + + IE YK +++R + Sbjct: 803 KDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 848 >5IDF-B nrPDB Length = 874 Score = 711 bits (1835), Expect = 0.0, Method: Composition-based stats. Identities = 202/890 (22%), Positives = 369/890 (41%), Gaps = 122/890 (13%) Query: 22 CDPKIVNIGAVL--STKKHEQIFREAVNQANKRHFTRKIQLNA---TSVTHRPNAIQMAL 76 P ++IG + +T + FR AV N T + + N+ + Sbjct: 9 KFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTN 68 Query: 77 SVCEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLS 136 + C S VYAI + + LT S+ + +T +D + Sbjct: 69 AFCSQF-SRGVYAIFGFYDQMSMNTLT----SFCGALHT---SFVTPSFPTDAD----VQ 116 Query: 137 FLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQ 196 F+ + P ++ + W + + + Q +E ++ + + Sbjct: 117 FVIQMRP--ALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVG 174 Query: 197 FEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GERE 253 + ++ E + + ++ + + + +L GY +++ G + Sbjct: 175 NIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTD 234 Query: 254 ISGSALRYAPDGIIGLQLINGK----------------------------NESAHISDAV 285 I + + I G Q++N + SA DA+ Sbjct: 235 ILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAI 294 Query: 286 AVVAQAIHELFEMENITDPPRG----CVGNTN-IWKTGPLFKRVLMSSKYPDGVTGRIEF 340 V+A+A L + + RG C+ N W G +R L + G+TG I+F Sbjct: 295 LVIAEAFRYL-RRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQV-QGMTGNIQF 352 Query: 341 NEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKI 400 + G R + ++ + G +N + +R + + + + + + Sbjct: 353 DTYGRRTNYTIDVYEMKVSGSRKAGYWN-----EYERFVPFSDQQISNDSSSSENRTIVV 407 Query: 401 VTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDL 460 TI + P+V + E Y G+CVDL Sbjct: 408 TTILESPYVMYKKNHEQLEGNERYE-----------------------------GYCVDL 438 Query: 461 LIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNE 520 ++A+ + Y++ +V DGK+G ++ K WNGM+GEL+ G+AD+ VAPLTI Sbjct: 439 AYEIAKHVGIKYKLSIVGDGKYGARD----PETKIWNGMVGELVYGRADIAVAPLTITLV 494 Query: 521 RAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLD 579 R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V+L+L+ Sbjct: 495 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 554 Query: 580 RFSPFGRFKVNSEEEEED---------ALTLSSAMWFSWGVLLNSGIGEGAPRSFSARIL 630 RFSP+ ++ EE D + +++WFS G + G + +PRS S RI+ Sbjct: 555 RFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIV 613 Query: 631 GMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIY 690 G VW F +II++SYTANLAAFL ++R I D + + Y T+ S + Sbjct: 614 GGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLDSGSTKEF 670 Query: 691 FRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKC 742 FRR M+ +M+ ++ A+ + VR +K AF+ +S + E+ E + C Sbjct: 671 FRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPC 730 Query: 743 DLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD-KTWVRYQECDSRSN 801 D + G G+G+ K S V+L +LK E G +++L K W EC ++ + Sbjct: 731 DTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDS 790 Query: 802 AP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQ 847 + L+ N+AGVF ++ GG+ + + IE YK +++R ++ Sbjct: 791 GSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLT 840 >4U1Y-A nrPDB Length = 819 Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats. Identities = 206/876 (23%), Positives = 370/876 (42%), Gaps = 117/876 (13%) Query: 25 KIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDLIS 84 + IG + ++ V ++ N+ + + C S Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLT-PHIDNLEVANSFAVTNAFCSQF-S 58 Query: 85 SQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPY 144 VYAI + + +T S+ + V +T F+ + P Sbjct: 59 RGVYAIFGFYDKKSVNTIT----SFCGTLH---VSFITPSFP----TDGTHPFVIQMRPD 107 Query: 145 SHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEK-ESKADKVLQFEPGTKN 203 ++ + W+ + D Q L++ E+K + A V K+ Sbjct: 108 --LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKD 165 Query: 204 LT--ALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREISGSA 258 T +L + + + R +IL D + + GY +++ G + Sbjct: 166 ETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLK 225 Query: 259 LRYAPDGIIGLQLINGK----------------------------NESAHISDAVAVVAQ 290 +++ + G Q+++ SA DAV V+ + Sbjct: 226 IQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTE 285 Query: 291 AIHELFEMENITDPPRG----CVGNTN-IWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGD 345 A L + I RG C+ N W G +R L + +G++G I+F+++G Sbjct: 286 AFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQV-EGLSGNIKFDQNGK 343 Query: 346 RKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQ 405 R +IM L+ ++G + + D+ ++ + G + T + + TI + Sbjct: 344 RINYTINIMELKTNGPRKIGYW-----SEVDKMVVTL--TEDDTSGLEQKTVV-VTTILE 395 Query: 406 EPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLA 465 P+V ++ E Y G+CVDL ++A Sbjct: 396 SPYVMMKKNHEMLEGNERYE-----------------------------GYCVDLAAEIA 426 Query: 466 REMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYI 525 + F Y++ +V DGK+G ++ ++ K WNGM+GEL+ G+AD+ +APLTI R + I Sbjct: 427 KHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVI 482 Query: 526 EFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPF 584 +FSKPF G++I++KK + + + SF+ P +W+ + + +V+V+L+L+ RFSP+ Sbjct: 483 DFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLVSRFSPY 542 Query: 585 GRFKVNSEEEEE--DALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIV 642 E+ EE + + ++ WF+ + G + +PRS SARI+ VW F +II+ Sbjct: 543 EWHTEEFEDGEESTNEFGIFNSFWFALKLFFQQG-ADISPRSLSARIVAGVWWFFTLIII 601 Query: 643 ASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTM 700 +SYTANLAAFL ++R I D + + Y T+ S +FRR M Sbjct: 602 SSYTANLAAFLTVERMVSPIESAEDLSKQT---EIAYGTLDSGSTKEFFRRSKIAVFDKM 658 Query: 701 YRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGELFFRS 754 + +M + AE + VR +K +A++ +S + E+ E + CD + G Sbjct: 659 WTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSK 718 Query: 755 GFGIGMRKDSPWKQNVSLNILKSHENGFMEELD-KTWVRYQECDSRSNAP----ATLTFE 809 G+GI K S V+L +LK E G +++L K W EC ++ + + L+ Sbjct: 719 GYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLS 778 Query: 810 NMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQ 845 N+AGVF ++ GG+ + + IE AYK +A+R + Sbjct: 779 NVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMK 814 >5UN1-G nrPDB Length = 451 Score = 656 bits (1692), Expect = 0.0, Method: Composition-based stats. Identities = 429/458 (93%), Positives = 438/458 (95%), Gaps = 9/458 (1%) Query: 394 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCC 453 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGP+ETIPGRPTVPQCC Sbjct: 1 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCC 60 Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 YGFCVDLLIKLAREM+FTYEVHLVADGKFGTQERVNNSN WNGMMGELLSGQADMIVA Sbjct: 61 YGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVA 120 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 573 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV Sbjct: 121 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 180 Query: 574 MLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMV 633 MLYLLDRFSPFGRF EDALTLSSAMWFSW VLLNSG+GEGAPRSFSARILGMV Sbjct: 181 MLYLLDRFSPFGRF--------EDALTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMV 232 Query: 634 WAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR 693 WAGFAMIIVASYTANLAAFLVL RPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR Sbjct: 233 WAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR 292 Query: 694 QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR 753 QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR Sbjct: 293 QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR 352 Query: 754 SGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAG 813 SGFGIGMRKDSPWKQ VSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAG Sbjct: 353 SGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAG 412 Query: 814 VFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQ-MQLAF 850 VFMLVAGGIVAGIFLIFIEIAYK +A+R + +++ F Sbjct: 413 VFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMKGLEVLF 450 >5UN1-B nrPDB Length = 448 Score = 554 bits (1428), Expect = e-158, Method: Composition-based stats. Identities = 157/469 (33%), Positives = 266/469 (56%), Gaps = 35/469 (7%) Query: 395 STRLKIVTIHQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCC 453 L IVT+ + PFV V GTC N P +K I N T G + +CC Sbjct: 1 DEHLSIVTLEEAPFVIVEDVDPLSGTCMR----NTVPCRKQI-RPENRTEEGGNYIKRCC 55 Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 GFC+D+L K+A+ + FTY+++LV +GK G + WNGM+GE+++ +A M V Sbjct: 56 KGFCIDILKKIAKTVKFTYDLYLVTNGKHGKK------INGVWNGMIGEVVTKRAYMAVG 109 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVV-A 572 LTIN ER++ ++FS PF G++++V + + +F++PF + +W+++ + + +V A Sbjct: 110 SLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSA 169 Query: 573 VMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGM 632 V +++ + FSP G + T+ A+W WG++ N+ + P+ +++I+ Sbjct: 170 VAVFVFEYFSPVGY--------NGPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVS 221 Query: 633 VWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD---KFIYATVKQSSVDI 689 VWA FA+I +ASYTANLAAF++ R ++++G++D + + P+D F + TV S + Sbjct: 222 VWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTER 281 Query: 690 YFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQK--CDLVTT 747 R M+ +M K N S +A+ +++ KL AFI+D+AVL + A + C LVT Sbjct: 282 NIRNN--YLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTI 339 Query: 748 --GELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSN--AP 803 G++F +G+GI ++KDS WK+ V L IL+ +G MEEL+ W+ C + N Sbjct: 340 GSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLT-GICHNEKNEVMS 398 Query: 804 ATLTFENMAGVFMLVAGGIVAGIFLIFIE-IAYKRHKDARRKQ-MQLAF 850 + L +NMAGVF ++A + + +E + YK +A+R + +++ F Sbjct: 399 SQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMKGLEVLF 447 >5KUH-A nrPDB Length = 757 Score = 448 bits (1153), Expect = e-126, Method: Composition-based stats. Identities = 125/572 (21%), Positives = 232/572 (40%), Gaps = 93/572 (16%) Query: 26 IVNIGAVL------STKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVC 79 ++ G + E FR AVN N+ + L T++T+ I + S Sbjct: 4 VLRFGGIFEYVESGPMGAEELAFRFAVNTINRN----RTLLPNTTLTYDTQKINLYDSFE 59 Query: 80 EDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLR 139 + ++ V+ P+ + + +P I + + +K ++ Sbjct: 60 ASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKD--SFYVS 117 Query: 140 TVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEP 199 P +S + ++++ F W V ++ D Q+ ++ + + K+ Q Sbjct: 118 LYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIK--APSRYNLRLKIRQLPA 175 Query: 200 GTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISG--- 256 TK+ LL E K + +I S + A + K A + M Y ++ ++ Sbjct: 176 DTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDV 235 Query: 257 SALRYAPDGIIGLQLINGKN--------------------------------ESAHISDA 284 RY+ + G +++N +N ++A + DA Sbjct: 236 EPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDA 295 Query: 285 VAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNE-D 343 V VV+ A+ + +M T C W+ G F ++ + +G+TGRI FN+ + Sbjct: 296 VHVVSVAVQQFPQM---TVSSLQC-NRHKPWRFGTRFMSLIKEAH-WEGLTGRITFNKTN 350 Query: 344 GDRKFANYSIMNLQNRKLVQVGIFNG-SYIIQNDRKIIWPGGETERPQGYQMSTRLKIVT 402 G R + +++L+ L ++G ++ S + + + P T+ L + T Sbjct: 351 GLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRS----LIVTT 406 Query: 403 IHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLI 462 I +EP+V + + + + G+C+DLL Sbjct: 407 ILEEPYVLFKKSDKPLYGNDRFE-----------------------------GYCIDLLR 437 Query: 463 KLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERA 522 +L+ + FTYE+ LV DGK+G Q+ VN +WNGM+ EL+ +AD+ VAPLTI R Sbjct: 438 ELSTILGFTYEIRLVEDGKYGAQDDVN----GQWNGMVRELIDHKADLAVAPLTITYVRE 493 Query: 523 QYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 + I+FSKPF G++IL +K P + D + Sbjct: 494 KVIDFSKPFMTLGISILYRKGTPIDSADDLAK 525 Score = 277 bits (708), Expect = 1e-74, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 104/224 (46%), Gaps = 11/224 (4%) Query: 654 VLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN--- 708 +L R I +D + K Y V+ S +F++ M+ M Sbjct: 509 ILYRKGTPIDSADDLAKQT---KIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSV 565 Query: 709 -YESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWK 767 +S+ E IQ V + +A + +S +EF + C+L G L G+G+G SP++ Sbjct: 566 LVKSSEEGIQRVLTSD-YALLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYR 624 Query: 768 QNVSLNILKSHENGFMEELDKTWVRYQEC-DSRSNAPATLTFENMAGVFMLVAGGIVAGI 826 +++ IL+ E G + + + W R C + S + L +N+ G+F+++A G+V + Sbjct: 625 DKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSV 684 Query: 827 FLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEP 870 F+ E YK K+A+ ++ A V R +L+ ++ + +P Sbjct: 685 FVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKP 728 >5L2E-A nrPDB Length = 688 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 121/598 (20%), Positives = 225/598 (37%), Gaps = 123/598 (20%) Query: 23 DPKIVNIGAVL--STKKHEQIFREAVNQANKRH---FTRKIQLNATSVTHRPNAIQMALS 77 I++IGA+ S KK +++FR AV N+ T KI + T V N Q Sbjct: 2 SDSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGN-NPFQAVQE 60 Query: 78 VCEDLISSQVYAILVS---------HPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIY 128 CE L++ + A++ S A H+ I + P G S Sbjct: 61 ACE-LMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTA--GTPRSGCGLTRSNR 117 Query: 129 SDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKE 188 +D + +V P + V ++ + W I+ +++ R Q+ L+ + + Sbjct: 118 ND-----DYTLSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKV---SQ 169 Query: 189 SKADKVLQ-FEPGTKNLTALLLEAKELEA--------RVIILSASEDDATAVYKSAAMLD 239 D LQ E + L + +E R IL + A + + Sbjct: 170 QGMDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETN 229 Query: 240 MTGAGYVWLVGEREISGSALRY-----------------APDGI----------IGLQLI 272 + W++ EI+ ++ P I I L Sbjct: 230 LVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLC 289 Query: 273 NGKNESAH--------ISDAVAVVAQAIH-ELFEMENITDPPRGCV-GNTNIWKTGPLFK 322 + K+ A I D V ++A A H +L + + + C+ N+ W+ G Sbjct: 290 DPKDPFAQNMEISNLYIYDTVLLLANAFHKKLQDRKWHSMASLSCIRKNSKPWQGGRSML 349 Query: 323 RVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQ-----NRKLVQVGIFNGSYIIQNDR 377 + +G+TG +EF E+G ++ I+ R + ++G +N + Sbjct: 350 ETIKKGGV-NGLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLN--- 405 Query: 378 KIIWPGGETERPQGYQM-STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVIC 436 G T++ M L++VT+ +EPFV V Sbjct: 406 -----GSLTDKKLENNMRGVVLRVVTVLEEPFVMV------------------------- 435 Query: 437 NGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEW 496 +E + G+P Q GF +D+L L+ + F YE+++ D K+G+ + W Sbjct: 436 ---SENVLGKPKKYQ---GFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQE-----DGTW 484 Query: 497 NGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 NG++GEL+ +AD+ ++ LTI +R ++F+ + + +L+++ +L + Sbjct: 485 NGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRGTSIQSLQDLSK 542 Score = 136 bits (343), Expect = 4e-32, Method: Composition-based stats. Identities = 54/226 (23%), Positives = 94/226 (41%), Gaps = 30/226 (13%) Query: 601 LSSAMWFSWGVLLNSGIGEGAPR--SFSARILGMVWAGFAMIIVASYTANLAAFLVLDRP 658 LS+ + F++ + + G+P+ ++G + A I +++ T V+D Sbjct: 457 LSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFT 516 Query: 659 EERI-----------TGINDPRLRNPSDKFIYATVKQSSVDIY--------FRRQVELST 699 + T I + + Y TV S+V + F R S Sbjct: 517 TRYMDYSVGVLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQ 576 Query: 700 MYRHMEKHN-----YESAAEAIQAVRDNKLHAFIWDSAVLEFEA--SQKCDLVTTGELFF 752 M+R + + N + IQ V+ +AF+WD+AVLE+ A C T G Sbjct: 577 MWRMINRSNGSENNVLESQAGIQKVKYGN-YAFVWDAAVLEYVAINDPDCSFYTVGNTVA 635 Query: 753 RSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD-KTWVRYQECD 797 G+GI ++ SP++ S IL+ ++G M+ L K W + +CD Sbjct: 636 DRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 681 >1YAE-A nrPDB Length = 312 Score = 261 bits (666), Expect = 1e-69, Method: Composition-based stats. Identities = 84/438 (19%), Positives = 146/438 (33%), Gaps = 139/438 (31%) Query: 380 IWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGP 439 P T+ L + TI +EP+V + + + + Sbjct: 1 GKPANITDSLSNRS----LIVTTILEEPYVLFKKSDKPLYGNDRFE-------------- 42 Query: 440 NETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGM 499 G+C+DLL +L+ + FTYE+ LV DGK+G Q+ VN +WNGM Sbjct: 43 ---------------GYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVN----GQWNGM 83 Query: 500 MGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQST 559 + EL+ + A L + L I +E + F +PF Sbjct: 84 VRELIDHK-----ADLAVAP----------------LAITYVREK----VIDFSKPF--- 115 Query: 560 LWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGE 619 ++++ K N + ++ Sbjct: 116 -------MTLGISIL-----------YRKPNGTNPGVFSFLNGGSL-------------- 143 Query: 620 GAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIY 679 PR +R E I +D + K Y Sbjct: 144 -VPRGS------------------------------ERMESPIDSADDLAKQT---KIEY 169 Query: 680 ATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNKLHAFIWDSAV 733 V+ + +F++ M+ M +S E IQ V + +AF+ +S Sbjct: 170 GAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD-YAFLMESTT 228 Query: 734 LEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRY 793 +EF + C+L G L G+G+G SP++ +++ IL+ E G + + + W R Sbjct: 229 IEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRG 288 Query: 794 QEC-DSRSNAPATLTFEN 810 C + S + L +N Sbjct: 289 NGCPEEESKEASALGVQN 306 >5I2K-B nrPDB Length = 293 Score = 225 bits (572), Expect = 1e-58, Method: Composition-based stats. Identities = 137/161 (85%), Positives = 147/161 (91%), Gaps = 2/161 (1%) Query: 393 QMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRP--TVP 450 MSTRLKIVTIHQEPFVYV+PT SDGTC+EE+T+NGDP+KKVIC GPN+T PG P TVP Sbjct: 2 SMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVP 61 Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 QCCYGFC+DLLIKLAR MNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM Sbjct: 62 QCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 121 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDS 551 IVAPLTINNERAQYIEFSKPFKYQGLTILVKK + ++ Sbjct: 122 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGIND 162 Score = 218 bits (556), Expect = 6e-57, Method: Composition-based stats. Identities = 146/184 (79%), Positives = 156/184 (84%), Gaps = 14/184 (7%) Query: 629 ILGMVWAGFAMIIVASYTAN--LAAFLVLDRPE------------ERITGINDPRLRNPS 674 ++G + +G A +IVA T N A ++ +P RITGINDPRLRNPS Sbjct: 110 MMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPS 169 Query: 675 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL 734 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL Sbjct: 170 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL 229 Query: 735 EFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQ 794 EFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSL+ILKSHENGFME+LDKTWVRYQ Sbjct: 230 EFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQ 289 Query: 795 ECDS 798 ECDS Sbjct: 290 ECDS 293 >2RC9-A nrPDB Length = 294 Score = 191 bits (486), Expect = 9e-49, Method: Composition-based stats. Identities = 56/188 (29%), Positives = 98/188 (52%), Gaps = 21/188 (11%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE---------------ERITGINDPRLRNP 673 ++G + +G A + V S++ N A V+D ++GI+DP+L +P Sbjct: 108 LVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRGTELSGIHDPKLHHP 167 Query: 674 SDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDN--KLHAFIWDS 731 S F + TV++SS + Y R+ M+ +M ++N + + +Q ++++ KL AFI D Sbjct: 168 SQGFRFGTVRESSAEDYVRQS--FPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDK 225 Query: 732 AVLEFEA--SQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKT 789 A+L++E C L+T G+ F G+GIG+ +SP N+S I + +GFM+ L Sbjct: 226 ALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDK 285 Query: 790 WVRYQECD 797 W + C Sbjct: 286 WYKVVPCG 293 Score = 168 bits (426), Expect = 8e-42, Method: Composition-based stats. Identities = 51/166 (30%), Positives = 87/166 (52%), Gaps = 13/166 (7%) Query: 393 QMSTRLKIVTIHQEPFVYVRPTTSDGTCR------EEYTINGDPIKKVICNGPNETIPGR 446 L++VT+ + PFV+ R +G C + T + + ++ + + Sbjct: 2 SNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVP 61 Query: 447 PTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSG 506 +CCYG+C+DLL +LA +MNF +++++V DGK+G + W G++G+LLSG Sbjct: 62 IKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK------NGHWTGLVGDLLSG 115 Query: 507 QADMIVAPLTINNERAQYIEFSKPFKYQGLTILVK-KEIPRSTLDS 551 A+M V +IN R+Q I+F+ PF L ILV+ + S + Sbjct: 116 TANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRGTELSGIHD 161 >2RCB-A nrPDB Length = 292 Score = 185 bits (469), Expect = 8e-47, Method: Composition-based stats. Identities = 54/188 (28%), Positives = 94/188 (50%), Gaps = 21/188 (11%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE---------------ERITGINDPRLRNP 673 ++G + AG A + V S++ N A V+D ++GI+DP+L +P Sbjct: 106 LVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRTRGTELSGIHDPKLHHP 165 Query: 674 SDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDN--KLHAFIWDS 731 S F + TV +SS + Y + M+ HM +H+ + + + + KL+AFI D Sbjct: 166 SQGFRFGTVWESSAEAYIKAS--FPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDK 223 Query: 732 AVLEFEA--SQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKT 789 ++L++E C L+T G+ F G+GIG+ ++SP N+S I + +GF++ L Sbjct: 224 SLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK 283 Query: 790 WVRYQECD 797 W + C Sbjct: 284 WYKMVPCG 291 Score = 168 bits (426), Expect = 8e-42, Method: Composition-based stats. Identities = 72/294 (24%), Positives = 136/294 (46%), Gaps = 38/294 (12%) Query: 397 RLKIVTIHQEPFVYVRPTTSDGTCR------EEYTINGDPIKKVICNGPNETIPGRPTVP 450 +L++VT+ + PFV+ R + DG C + T + + + N ++P T+ Sbjct: 6 KLRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPR--TLR 63 Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 +CCYG+C+DLL +LA ++ F +E+++V DGK+G W G++G+LL+G+A M Sbjct: 64 RCCYGYCIDLLERLAEDLAFDFELYIVGDGKYGALR------DGRWTGLVGDLLAGRAHM 117 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVK-KEIPRSTLDS--FMQPFQ----STLWLL 563 V +IN+ R+Q ++F+ PF L I+V+ + S + P Q T+W Sbjct: 118 AVTSFSINSARSQVVDFTSPFFSTSLGIMVRTRGTELSGIHDPKLHHPSQGFRFGTVWES 177 Query: 564 VGLSVHVVAV--MLYLLDRFS----PFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGI 617 + + M + R S P G + S+ + +A + ++ + V +++ Sbjct: 178 SAEAYIKASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSL-LDYEVSIDADC 236 Query: 618 ---GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDP 668 G P + G + + T+NL+ F+ + I ++D Sbjct: 237 KLLTVGKPFAIEG-------YGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK 283 >5H8N-A nrPDB Length = 285 Score = 184 bits (466), Expect = 2e-46, Method: Composition-based stats. Identities = 57/191 (29%), Positives = 97/191 (50%), Gaps = 24/191 (12%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE--------------ERITGINDPRLRNPS 674 ++G V A++ V S T N V+D ++TG++D + + P Sbjct: 98 MIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPH 157 Query: 675 D---KFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDS 731 D F + TV S + R M+++M K N + +A+ +++ KL AFI+D+ Sbjct: 158 DYSPPFRFGTVPNGSTERNIRNN--YPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDA 215 Query: 732 AVLEFEASQK--CDLVTTG--ELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD 787 AVL ++A + C LVT G +F +G+GI ++K SPWK+ + L +L+ +G MEEL+ Sbjct: 216 AVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELE 275 Query: 788 KTWVRYQECDS 798 W+ C + Sbjct: 276 TLWLT-GICHN 285 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 61/172 (35%), Positives = 93/172 (54%), Gaps = 15/172 (8%) Query: 391 GYQMSTRLKIVTIHQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTV 449 G L IVT+ + PFV V TC N P +K + N + V Sbjct: 1 GSPDDNHLSIVTLEEAPFVIVEDIDPLTETCVR----NTVPCRKFVK--INNSTNEGMNV 54 Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 +CC GFC+D+L KL+R + FTY+++LV +GK G ++VNN WNGM+GE++ +A Sbjct: 55 KKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHG--KKVNNV----WNGMIGEVVYQRAV 108 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDS--FMQPFQST 559 M V LTIN ER++ ++FS PF G++++V + + L F +P + Sbjct: 109 MAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYS 160 >3OEK-A nrPDB Length = 286 Score = 182 bits (462), Expect = 6e-46, Method: Composition-based stats. Identities = 53/166 (31%), Positives = 87/166 (52%), Gaps = 13/166 (7%) Query: 393 QMSTRLKIVTIHQEPFVYVRPTTS-DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQ 451 + L + T+ + PFV V P GTC + + + P+ P + + Sbjct: 2 DDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEK----R 57 Query: 452 CCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMI 511 CC GFC+D+L +LA + F+Y+++LV +GK G + WNGM+GE+ +ADM Sbjct: 58 CCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKK------IDGVWNGMIGEVFYQRADMA 111 Query: 512 VAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDS--FMQP 555 + LTIN ER++ ++FS PF G++++V + S L F +P Sbjct: 112 IGSLTINEERSEIVDFSVPFVETGISVMVARGTTVSGLSDRKFQRP 157 Score = 169 bits (429), Expect = 3e-42, Method: Composition-based stats. Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 24/191 (12%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE--------------ERITGINDPRLRNPS 674 ++G V+ A + + S T N ++D ++G++D + + P Sbjct: 99 MIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARGTTVSGLSDRKFQRPQ 158 Query: 675 DKF---IYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDS 731 +++ + TV S + R M+ +M ++N EA+ ++ KL AFI+D+ Sbjct: 159 EQYPPLKFGTVPNGSTEKNIRSN--YPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDA 216 Query: 732 AVLEFEASQK--CDLVTTG--ELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD 787 AVL + A + C LVT G ++F +G+GI + K S WK+ + L +L+ + +E L+ Sbjct: 217 AVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLE 276 Query: 788 KTWVRYQECDS 798 + W+ C + Sbjct: 277 RLWL-SGICHN 286 >4MF3-A nrPDB Length = 261 Score = 178 bits (451), Expect = 1e-44, Method: Composition-based stats. Identities = 40/202 (19%), Positives = 73/202 (36%), Gaps = 24/202 (11%) Query: 618 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLD--------------RPEERIT 663 G + ++ + A + VA T V+D R I Sbjct: 63 GAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPID 122 Query: 664 GINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQ 717 +D + K Y V+ S +F++ M+ M ++ E IQ Sbjct: 123 SADDLAKQT---KIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQ 179 Query: 718 AVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKS 777 V +A + +S +E+ + C+L G L G+G+G SP++ +++ IL+ Sbjct: 180 RVLTTD-YALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQL 238 Query: 778 HENGFMEELDKTWVRYQECDSR 799 E G + + + W R C Sbjct: 239 QEEGKLHMMKEKWWRGNGCPEE 260 Score = 162 bits (410), Expect = 6e-40, Method: Composition-based stats. Identities = 52/160 (32%), Positives = 78/160 (48%), Gaps = 34/160 (21%) Query: 395 STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCY 454 + L + TI +EP+V R + + + Sbjct: 4 NRTLIVTTILEEPYVMYRKSDKPLYGNDRFE----------------------------- 34 Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C+DLL +L+ + F Y+V LV DGK+G Q +K EWNGM+ EL+ +AD+ VAP Sbjct: 35 GYCLDLLKELSNILGFIYDVKLVPDGKYGAQN-----DKGEWNGMVKELIDHRADLAVAP 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 LTI R + I+FSKPF G++IL +K P + D + Sbjct: 90 LTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAK 129 >2XXT-A nrPDB Length = 261 Score = 178 bits (450), Expect = 1e-44, Method: Composition-based stats. Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 10/149 (6%) Query: 654 VLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN--- 708 +L R I +D + K Y V+ + +F++ M+ M Sbjct: 113 ILYRKGTPIDSADDLAKQT---KIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSV 169 Query: 709 -YESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWK 767 +S E IQ V + +AF+ +S +EF + C+L G L G+G+G SP++ Sbjct: 170 LVKSNEEGIQRVLTSD-YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYR 228 Query: 768 QNVSLNILKSHENGFMEELDKTWVRYQEC 796 +++ IL+ E G + + + W R C Sbjct: 229 DKITIAILQLQEEGKLHMMKEKWWRGNGC 257 Score = 164 bits (415), Expect = 1e-40, Method: Composition-based stats. Identities = 51/160 (31%), Positives = 79/160 (49%), Gaps = 33/160 (20%) Query: 395 STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCY 454 + L + TI +EP+V + + + + Sbjct: 3 NRSLIVTTILEEPYVLFKKSDKPLYGNDRFE----------------------------- 33 Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+C+DLL +L+ + FTYE+ LV DGK+G Q+ VN +WNGM+ EL+ +AD+ VAP Sbjct: 34 GYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVN----GQWNGMVRELIDHKADLAVAP 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 L I R + I+FSKPF G++IL +K P + D + Sbjct: 90 LAITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAK 129 >3DP4-A nrPDB Length = 278 Score = 176 bits (445), Expect = 4e-44, Method: Composition-based stats. Identities = 47/192 (24%), Positives = 77/192 (40%), Gaps = 26/192 (13%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE--------------ERITGINDPRLRNPS 674 ++G + G A I VA T L V+D + I D + Sbjct: 90 MVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLAKQT-- 147 Query: 675 DKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAF 727 + Y T+ S +FRR M+ +M+ ++ A+ + VR +K AF Sbjct: 148 -EIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAF 206 Query: 728 IWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL 786 + +S + E+ E + CD + G G+G+ K S V+L +LK E G +++L Sbjct: 207 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKL 266 Query: 787 D-KTWVRYQECD 797 K W EC Sbjct: 267 KNKWWYDKGECG 278 Score = 159 bits (403), Expect = 3e-39, Method: Composition-based stats. Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 33/173 (19%) Query: 382 PGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNE 441 + + + TI + P+V + E Y Sbjct: 6 SAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYE---------------- 49 Query: 442 TIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMG 501 G+CVDL ++A+ + Y++ +V DGK+G ++ K WNGM+G Sbjct: 50 -------------GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD----PETKIWNGMVG 92 Query: 502 ELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 EL+ G+AD+ VAPLTI R + I+FSKPF G++I++KK P + + + Sbjct: 93 ELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLAK 145 >3FAT-A nrPDB Length = 260 Score = 174 bits (440), Expect = 2e-43, Method: Composition-based stats. Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 26/192 (13%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE--------------ERITGINDPRLRNPS 674 ++G + G A I +A T L V+D + I D + Sbjct: 72 MVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLAKQT-- 129 Query: 675 DKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAF 727 + Y T+ S +FRR M+ +M + AE + VR +K AF Sbjct: 130 -EIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAF 188 Query: 728 IWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL 786 + +S + E+ E + CD + G G+G+ K S + V+L +LK E G +++L Sbjct: 189 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKL 248 Query: 787 D-KTWVRYQECD 797 K W EC Sbjct: 249 KNKWWYDKGECG 260 Score = 155 bits (392), Expect = 7e-38, Method: Composition-based stats. Identities = 44/160 (27%), Positives = 79/160 (49%), Gaps = 33/160 (20%) Query: 395 STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCY 454 + + TI + P+V + ++Y Sbjct: 1 GRTVVVTTIMESPYVMYKKNHEMFEGNDKYE----------------------------- 31 Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+CVDL ++A+ + Y++ +V DGK+G ++ ++ K WNGM+GEL+ G+A++ +AP Sbjct: 32 GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVYGKAEIAIAP 87 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 LTI R + I+FSKPF G++I++KK P + + + Sbjct: 88 LTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLAK 127 >5O9A-A nrPDB Length = 264 Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats. Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 26/193 (13%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPE--------------ERITGINDPRLRNPS 674 ++G + G A I +A T V+D + I D + Sbjct: 74 MVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQT-- 131 Query: 675 DKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAF 727 + Y T+ S +FRR M+ +M + AE + VR +K +A+ Sbjct: 132 -EIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAY 190 Query: 728 IWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL 786 + +S + E+ E + CD + G G+GI K S V+L +LK E G +++L Sbjct: 191 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKL 250 Query: 787 D-KTWVRYQECDS 798 K W EC S Sbjct: 251 KNKWWYDKGECGS 263 Score = 161 bits (408), Expect = 9e-40, Method: Composition-based stats. Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 33/160 (20%) Query: 395 STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCY 454 + + + TI + P+V ++ E Y Sbjct: 3 NKTVVVTTILESPYVMMKKNHEMLEGNERYE----------------------------- 33 Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G+CVDL ++A+ F Y++ +V DGK+G ++ ++ K WNGM+GEL+ G+AD+ +AP Sbjct: 34 GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGELVYGKADIAIAP 89 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 LTI R + I+FSKPF G++I++KK P + + + Sbjct: 90 LTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSK 129 >5IKB-A nrPDB Length = 257 Score = 169 bits (427), Expect = 6e-42, Method: Composition-based stats. Identities = 46/201 (22%), Positives = 77/201 (38%), Gaps = 26/201 (12%) Query: 616 GIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLD--------------RPEER 661 G+ E ++G + A A + VA T V+D R Sbjct: 62 GVPEAN--GTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKGTP 119 Query: 662 ITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQV--ELSTMYRHM----EKHNYESAAEA 715 I ++D + Y T+ S +F+ M+ +M +S E Sbjct: 120 IESVDDLADQT---AIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEG 176 Query: 716 IQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNIL 775 I V ++ +AF+ +S + E+ + C+L G L G+GIGM S ++ L IL Sbjct: 177 IARVLNSN-YAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAIL 235 Query: 776 KSHENGFMEELDKTWVRYQEC 796 + EN +E L + W +C Sbjct: 236 QLQENNRLEILKRKWWEGGKC 256 Score = 153 bits (387), Expect = 3e-37, Method: Composition-based stats. Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 38/192 (19%) Query: 395 STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCY 454 +T L + TI + P++ ++ D + Y Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYE----------------------------- 33 Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GFCVD+L +LA + F Y++ LV DG +G E W GM+GEL++ +AD+ VA Sbjct: 34 GFCVDMLKELAEILRFNYKIRLVGDGVYGVPE-----ANGTWTGMVGELIARKADLAVAG 88 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVM 574 LTI ER + I+FSKPF G++IL +K P ++D G ++ Sbjct: 89 LTITAEREKVIDFSKPFMTLGISILYRKGTPIESVDDLADQTAIE----YGTIHGGSSMT 144 Query: 575 LYLLDRFSPFGR 586 + R+ + R Sbjct: 145 FFQNSRYQTYQR 156 >4IGR-A nrPDB Length = 258 Score = 168 bits (424), Expect = 1e-41, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 9/148 (6%) Query: 654 VLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEK---HN 708 +L R I +D + K Y VK + +F++ M+ M Sbjct: 114 ILYRKGTPIDSADDLAKQT---KIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSAL 170 Query: 709 YESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQ 768 ++ E IQ +A + +S +E+ + C+L G L G+GIG SP++ Sbjct: 171 VKNNEEGIQRTLTAD-YALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRD 229 Query: 769 NVSLNILKSHENGFMEELDKTWVRYQEC 796 +++ IL+ E + + + W R C Sbjct: 230 KITIAILQLQEEDKLHIMKEKWWRGSGC 257 Score = 164 bits (415), Expect = 2e-40, Method: Composition-based stats. Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 34/164 (20%) Query: 391 GYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVP 450 G + L + T+ +EPFV R + + + Sbjct: 1 GPGTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFE------------------------- 35 Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 G+C+DLL +LA + F+YE+ LV DGK+G Q+ +K +WNGM+ EL+ +AD+ Sbjct: 36 ----GYCIDLLKELAHILGFSYEIRLVEDGKYGAQD-----DKGQWNGMVKELIDHKADL 86 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 VAPLTI + R + I+FSKPF G++IL +K P + D + Sbjct: 87 AVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAK 130 >5X2M-A nrPDB Length = 461 Score = 159 bits (401), Expect = 6e-39, Method: Composition-based stats. Identities = 81/419 (19%), Positives = 146/419 (34%), Gaps = 86/419 (20%) Query: 32 VLSTKKHEQIFREAVNQAN-KRHFTRKIQLNATSVTHRPN-----------AIQMALSVC 79 +L + Q+ R +V + N + L H + ++ + Sbjct: 45 ILPNYRRFQMMRFSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPW 104 Query: 80 EDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLR 139 ED + AI V P T L+ PI T F P++ S++S ++++ SFLR Sbjct: 105 EDASTGLPNAIGVVGPFTSTHALSIAPIFMTNLF---PMVSYGCSGSVFSKENLYPSFLR 161 Query: 140 TVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEP 199 TV ++ FNW V + SDD G+ ++ + +E+ E L F Sbjct: 162 TVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSE----ICLAFYK 217 Query: 200 GTKNLTALLLEAKELEA---RVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISG 256 T L K++E +VI++ A + A AV +SA L++T VW+ + Sbjct: 218 AINVNTDYLQVFKQIEEQNIKVIVVFAPKVYAEAVVESAVQLNVTNK--VWIADDGWSLN 275 Query: 257 ----------------------------SALRYAP---------------------DGII 267 + Y+ + Sbjct: 276 KKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFIYSAISQTDGGDTEQKMFCNQKCNCSNLS 335 Query: 268 GLQLINGKNESAH-ISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLM 326 L+N + + AV +A A+H C N + + L Sbjct: 336 VKSLLNADPSFSFPVYAAVYAIAHALHNTLR-----CGSDRCPKNITV--HPHMILEELK 388 Query: 327 SSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRK-LVQVGIF---NGSYIIQNDRKIIW 381 S + + ++F+E+GD KF + S++ + +VG + + ++ N KI W Sbjct: 389 KSNFTL-LNQTVQFDENGDPKFGSLSVVFWNSSGNAEEVGSYHFQSSIHLSINKTKIKW 446 >5K5S-A nrPDB Length = 615 Score = 157 bits (396), Expect = 2e-38, Method: Composition-based stats. Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 9/203 (4%) Query: 80 EDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLR 139 ++ + + T T ++ G + IP + + + S+K+ SFLR Sbjct: 126 DEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLR 185 Query: 140 TVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKAD--KVLQF 197 T+P HQA +++ F WN V I +DD GR +K EE++ D +++ Sbjct: 186 TIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQ 245 Query: 198 EPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGS 257 + + ++ + A+VI++ +S D + K ++TG +WL E S S Sbjct: 246 YSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGK--IWLASEAWASSS 303 Query: 258 ALR-----YAPDGIIGLQLINGK 275 + + G IG L G+ Sbjct: 304 LIAMPQYFHVVGGTIGFALKAGQ 326 >5FBH-B nrPDB Length = 568 Score = 157 bits (396), Expect = 2e-38, Method: Composition-based stats. Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 9/203 (4%) Query: 80 EDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLR 139 ++ + + T T ++ G + IP + + + S+K+ SFLR Sbjct: 153 DEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLR 212 Query: 140 TVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKAD--KVLQF 197 T+P HQA +++ F WN V I +DD GR +K EE++ D +++ Sbjct: 213 TIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQ 272 Query: 198 EPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGS 257 + + ++ + A+VI++ +S D + K ++TG +WL E S S Sbjct: 273 YSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGK--IWLASEAWASSS 330 Query: 258 ALR-----YAPDGIIGLQLINGK 275 + + G IG L G+ Sbjct: 331 LIAMPQYFHVVGGTIGFALKAGQ 353 >5EHM-A nrPDB Length = 268 Score = 156 bits (395), Expect = 3e-38, Method: Composition-based stats. Identities = 42/224 (18%), Positives = 80/224 (35%), Gaps = 31/224 (13%) Query: 601 LSSAMWFSWGVLLNSGIGEGAPRSFSAR---ILGMVWAGFAMIIVASYTANLAAFLVLD- 656 +S ++ F++ + L G+ + ++ + A + +A T +D Sbjct: 47 ISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDF 106 Query: 657 -------------RPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMY 701 R I D + + Y +K S +FR M+ Sbjct: 107 TTPFMNLGVSILYRKGTPIESAEDLAKQT---RIKYGALKGGSTAAFFRDSKISTYQRMW 163 Query: 702 RHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEFEASQKCDLVTTGELFFRSGF 756 ME S E ++ V K +AF+ +S +E+ + C+L G + + Sbjct: 164 SFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSY 223 Query: 757 GIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVR----YQEC 796 GI +SP++ ++ ILK E G + L W + +C Sbjct: 224 GIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKC 267 Score = 139 bits (349), Expect = 7e-33, Method: Composition-based stats. Identities = 47/214 (21%), Positives = 87/214 (40%), Gaps = 37/214 (17%) Query: 390 QGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTV 449 + L + TI P+ + + + +++ Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFE------------------------ 37 Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 G+ VDL+ ++++ + F Y++ LV DG +G+ ++ EWNGM+ ELL +AD Sbjct: 38 -----GYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKL----TGEWNGMIRELLEQRAD 88 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVH 569 + +A LTI ER Q ++F+ PF G++IL +K P + + + + L G Sbjct: 89 LAIADLTITFEREQAVDFTTPFMNLGVSILYRKGTPIESAEDLAKQTRIKYGALKG---- 144 Query: 570 VVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSS 603 + + S + R E T S+ Sbjct: 145 GSTAAFFRDSKISTYQRMWSFMESARPSVFTASN 178 >5DT6-A nrPDB Length = 267 Score = 149 bits (377), Expect = 4e-36, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 77/188 (40%), Gaps = 19/188 (10%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDR-----------PEERITGINDPRLRNPSDKF 677 ++G + A I +++ T V+D ++ T I P Sbjct: 80 MVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKGTPIKTPEDLTMQTDV 139 Query: 678 IYATVKQSSVDIYFRRQVE--LSTMYRHM---EKHNYESAAEAIQAVRDNK-LHAFIWDS 731 Y T+ S +FRR + M+ +M + H+ + E I+ VR +K +A + +S Sbjct: 140 NYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRRVRQSKGKYALLVES 199 Query: 732 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEEL-DKT 789 E+ A CD + G GFG+ SP ++ ++ +L ENG + + +K Sbjct: 200 PKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKW 259 Query: 790 WVRYQECD 797 W EC+ Sbjct: 260 WFDKTECN 267 Score = 136 bits (341), Expect = 6e-32, Method: Composition-based stats. Identities = 44/163 (26%), Positives = 77/163 (47%), Gaps = 30/163 (18%) Query: 390 QGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTV 449 Y + + ++ +EP++ ++ T + ++ N E Sbjct: 1 GSYDRNHTYIVSSLLEEPYLSLKQYTYG--------------ESLVGNDRFE-------- 38 Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 G+C DL LA ++ YE+ LV DG +G + N W+GM+GEL+ +AD Sbjct: 39 -----GYCKDLADMLAAQLGIKYEIRLVQDGNYGAE---NQYAPGGWDGMVGELIRKEAD 90 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 + ++ +TI ER + I+FSKPF G++I++KK P T + Sbjct: 91 IAISAMTITAERERVIDFSKPFMTLGISIMIKKGTPIKTPEDL 133 >2E4V-A nrPDB Length = 555 Score = 144 bits (363), Expect = 2e-34, Method: Composition-based stats. Identities = 41/189 (21%), Positives = 80/189 (42%), Gaps = 10/189 (5%) Query: 90 ILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQAL 149 +L++ + ++ ++IP I + + SDKS + F RTVPP +QA Sbjct: 116 LLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAK 175 Query: 150 VWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESK---ADKVLQFEPGTKNLTA 206 E++R FNW +V + S+ G + E + A+KV + + Sbjct: 176 AMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSV 235 Query: 207 LLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSAL----RYA 262 + ++ ARV++L DD+ + +A + A + W+ + + ++ + Sbjct: 236 IRELLQKPNARVVVLFMRSDDSRELIAAA---NRVNASFTWVASDGWGAQESIVKGSEHV 292 Query: 263 PDGIIGLQL 271 G I L+L Sbjct: 293 AYGAITLEL 301 >5CNM-A nrPDB Length = 517 Score = 143 bits (359), Expect = 4e-34, Method: Composition-based stats. Identities = 41/189 (21%), Positives = 81/189 (42%), Gaps = 10/189 (5%) Query: 90 ILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQAL 149 +L++ + ++ ++IP I + + SDKS + F RTVPP +QA Sbjct: 142 LLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAK 201 Query: 150 VWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE---KESKADKVLQFEPGTKNLTA 206 E++R FNW +V + S+ G + E + A+KV + + Sbjct: 202 AMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNISIATAEKVGRSNIRKSYDSV 261 Query: 207 LLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSAL----RYA 262 + ++ ARV++L DD+ + +A+ + A + W+ + + ++ + Sbjct: 262 IRELLQKPNARVVVLFMRSDDSRELIAAASRAN---ASFTWVASDGWGAQESIIKGSEHV 318 Query: 263 PDGIIGLQL 271 G I L+L Sbjct: 319 AYGAITLEL 327 >5CNI-A nrPDB Length = 503 Score = 142 bits (357), Expect = 8e-34, Method: Composition-based stats. Identities = 42/176 (23%), Positives = 76/176 (43%), Gaps = 16/176 (9%) Query: 106 PISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVIL 165 ++ ++IP I + + SDKS + F RTVPP QA E++R FNW +V Sbjct: 152 QVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVST 211 Query: 166 IVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLE------AKELEARVI 219 + S EG + +E E ++ V E + ++ E ++ ARV Sbjct: 212 VAS---EGDYGETGIEAFELEARARNISVATSEKVGRAMSRAAFEGVVRALLQKPSARVA 268 Query: 220 ILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSAL----RYAPDGIIGLQL 271 +L +DA + ++ L+ A + W+ + + + A +G I ++L Sbjct: 269 VLFTRSEDARELLAASQRLN---ASFTWVASDGWGALEEVVAGSEGAAEGAITIEL 321 >5KZQ-A nrPDB Length = 570 Score = 141 bits (356), Expect = 1e-33, Method: Composition-based stats. Identities = 42/176 (23%), Positives = 77/176 (43%), Gaps = 16/176 (9%) Query: 106 PISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVIL 165 ++ ++IP I + + SDKS + F RTVPP QA E++R FNW +V Sbjct: 150 QVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVST 209 Query: 166 IVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLE------AKELEARVI 219 + S EG + +E E ++ V E + ++ E ++ ARV Sbjct: 210 VAS---EGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVA 266 Query: 220 ILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSAL----RYAPDGIIGLQL 271 +L +DA + ++ L+ A + W+ + + ++ A +G I ++L Sbjct: 267 VLFTRSEDARELLAASQRLN---ASFTWVASDGWGALESVVAGSEGAAEGAITIEL 319 >4WXJ-A nrPDB Length = 269 Score = 139 bits (350), Expect = 5e-33, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 74/183 (40%), Gaps = 26/183 (14%) Query: 638 AMIIVASYTANLAAFLVLDRPE--------------ERITGINDPRLRNPSDKFIYATVK 683 A I + T A V+D I ++D +N K + T++ Sbjct: 90 AQIGICDLTITQARRSVVDFTVPFMQLGISILSYKGTDIGSLHDLVDQN---KVQFGTIR 146 Query: 684 QSSVDIYFRRQVELSTMYRHMEKHNYES------AAEAIQAVRDNK-LHAFIWDSAVLEF 736 + +YF + + +++ E + V+ +K +AF+ ++ L++ Sbjct: 147 GGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQY 206 Query: 737 EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQE- 795 + C+L GE F +GI + ++ ++ N+S+ IL+ E G + +L W E Sbjct: 207 YVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNES 266 Query: 796 -CD 797 CD Sbjct: 267 TCD 269 Score = 117 bits (292), Expect = 3e-26, Method: Composition-based stats. Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%) Query: 421 REEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADG 480 YT+ K E + G+ VDL+ LA+E F + V D Sbjct: 8 PIRYTVATRVGKPYFS-WREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDN 66 Query: 481 KFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILV 540 K+G+ + +N EW+G++ +L+ A + + LTI R ++F+ PF G++IL Sbjct: 67 KYGSYD----ANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILS 122 Query: 541 KKEIPRSTLDSFMQ 554 K +L + Sbjct: 123 YKGTDIGSLHDLVD 136 >5CC2-A nrPDB Length = 265 Score = 138 bits (347), Expect = 1e-32, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 74/160 (46%), Gaps = 36/160 (22%) Query: 395 STRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCY 454 L++VT+ +EPFV V +E + G+P Q Sbjct: 2 GVVLRVVTVLEEPFVMV----------------------------SENVLGKPKKYQ--- 30 Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +D+L L+ + F YE+++ D K+G+ + WNG++GEL+ +AD+ ++ Sbjct: 31 GFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQE-----DGTWNGLVGELVFKRADIGISA 85 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 LTI +R ++F+ + + +L+++ +L + Sbjct: 86 LTITPDRENVVDFTTRYMDYSVGVLLRRGTSIQSLQDLSK 125 Score = 136 bits (343), Expect = 4e-32, Method: Composition-based stats. Identities = 54/226 (23%), Positives = 94/226 (41%), Gaps = 30/226 (13%) Query: 601 LSSAMWFSWGVLLNSGIGEGAPR--SFSARILGMVWAGFAMIIVASYTANLAAFLVLDRP 658 LS+ + F++ + + G+P+ ++G + A I +++ T V+D Sbjct: 40 LSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFT 99 Query: 659 EERI-----------TGINDPRLRNPSDKFIYATVKQSSVDIY--------FRRQVELST 699 + T I + + Y TV S+V + F R S Sbjct: 100 TRYMDYSVGVLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQ 159 Query: 700 MYRHMEKHN-----YESAAEAIQAVRDNKLHAFIWDSAVLEFEA--SQKCDLVTTGELFF 752 M+R + + N + IQ V+ +AF+WD+AVLE+ A C T G Sbjct: 160 MWRMINRSNGSENNVLESQAGIQKVKYGN-YAFVWDAAVLEYVAINDPDCSFYTVGNTVA 218 Query: 753 RSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELD-KTWVRYQECD 797 G+GI ++ SP++ S IL+ ++G M+ L K W + +CD Sbjct: 219 DRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 264 >6BT5-A nrPDB Length = 479 Score = 130 bits (327), Expect = 3e-30, Method: Composition-based stats. Identities = 37/168 (22%), Positives = 75/168 (44%), Gaps = 9/168 (5%) Query: 92 VSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVW 151 +S ++ ++IP I + SD + + F R VPP S+QA Sbjct: 111 ISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAM 170 Query: 152 FEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE----KESKADKV-LQFEPGT-KNLT 205 +++ WN+V + S+ + G + + + E +++ K+ + PG + + Sbjct: 171 VDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVSIAQSQKIPREPRPGEFEKII 230 Query: 206 ALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGERE 253 LLE AR +I+ A+EDD + ++A L+ +G ++W+ + Sbjct: 231 KRLLET--PNARAVIMFANEDDIRRILEAAKKLNQSGH-FLWIGSDSW 275 >5C5C-A nrPDB Length = 481 Score = 123 bits (308), Expect = 3e-28, Method: Composition-based stats. Identities = 34/191 (17%), Positives = 73/191 (38%), Gaps = 15/191 (7%) Query: 92 VSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVW 151 V + ++ ++IP I + SD + F R VPP S QA Sbjct: 118 VVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAM 177 Query: 152 FEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEE----KESKADKVLQFEP----GTKN 203 ++++ WN+V + S+ G + + +E +++ ++ Q Sbjct: 178 VDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLSIAQSVRIPQERKDRTIDFDR 237 Query: 204 LTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREIS----GSAL 259 + LL+ +R +++ A+++D + +A D G ++W+ + S Sbjct: 238 IIKQLLDT--PNSRAVVIFANDEDIKQILAAAKRADQVGH-FLWVGSDSWGSKINPLHQH 294 Query: 260 RYAPDGIIGLQ 270 +G I +Q Sbjct: 295 EDIAEGAITIQ 305 >5X2N-B nrPDB Length = 478 Score = 116 bits (291), Expect = 4e-26, Method: Composition-based stats. Identities = 61/362 (16%), Positives = 125/362 (34%), Gaps = 71/362 (19%) Query: 97 APTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMR 156 P T I GF+ +P I +SD ++ SF RTVP Q ++++ Sbjct: 127 GPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLVYPSFFRTVPSDIRQVDAMVQLIK 186 Query: 157 LFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKA--DKVLQFEPGTK-NLTALLLEAKE 213 FNWN V ++ S++ G+ ++ E+ ++ K + ++ + Sbjct: 187 KFNWNWVAVVGSEEEYGQQGVQQFSKKAEDMGVCVAYQGLIPIYDDPKPAIQTIINNIQT 246 Query: 214 LEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYAP-----DGIIG 268 E +V+++ + A + ++ ++TG VW+ + P +IG Sbjct: 247 TEVKVVVVFSLVSPAVSFFEEVIKKNLTG---VWIASSSWAISDKVYSLPNIDSIGTVIG 303 Query: 269 L-------QLING--------------------------------------------KNE 277 +L++ + Sbjct: 304 FIDETETLELLSPFTEVLFKKIHEASPTEKPEDPYNPCPECWSLSPANVSLVKEESVQRT 363 Query: 278 SAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGR 337 + + AV VA A+H+L E C +++ VL T Sbjct: 364 AFSVYAAVYTVAHALHKLLE-----CNSAACKWSSSTRLYPWKLLEVLKEFSVNISNT-S 417 Query: 338 IEFNEDGDRKFANYSIMN--LQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMS 395 ++F+++G YS++ +N+ L VG + + + N+ W +E+P+ + Sbjct: 418 LKFDQNG-NPNIGYSVIQRIWENQSLSSVGSYRSANLSINETLFKWYTNNSEKPESSGIE 476 Query: 396 TR 397 R Sbjct: 477 GR 478 >4YKP-A nrPDB Length = 256 Score = 115 bits (288), Expect = 9e-26, Method: Composition-based stats. Identities = 39/154 (25%), Positives = 65/154 (42%), Gaps = 35/154 (22%) Query: 390 QGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTV 449 + L++ ++ ++PF++ +G Sbjct: 2 SKNLIGRHLRLGSVEEQPFMFFATEGCEGN------------------------------ 31 Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 C G D+++KL+ ++ FTYE D KFG + N EWNGM+ +LL + D Sbjct: 32 -DCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTN----EWNGMIRDLLDDKTD 86 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 MI L+ N+ R I++S PF G+ +VK E Sbjct: 87 MIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGE 120 Score = 96.4 bits (238), Expect = 5e-20, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Query: 674 SDKFIYATVKQSSVDIYFR--RQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDS 731 DK+ + + + + R S + E + AI+ +R L FI + Sbjct: 133 QDKYKWGVIGSRHPETLLKTHRDSRYSRLVD--EGVELKDLNHAIETLR-GGLFVFIDEG 189 Query: 732 AVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWV 791 VL CD+ + GE F + G+ KDSP+K + ++LK E GF++ L + W Sbjct: 190 PVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWS 249 Query: 792 RYQ 794 Sbjct: 250 SGN 252 >4ZDM-A nrPDB Length = 261 Score = 108 bits (269), Expect = 1e-23, Method: Composition-based stats. Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Query: 450 PQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 509 P C G V+++ +++++NFTY D KFG + NS EWNG++ +LL + D Sbjct: 34 PSCYTGVNVEIVSMMSQDLNFTYNFITPEDLKFGGK----NSTTGEWNGLIRDLLDNKTD 89 Query: 510 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE 543 MIV L+ N R I+FS GL LVK + Sbjct: 90 MIVVALSNNAVRKADIDFSLSMMDGGLGALVKSD 123 Score = 72.5 bits (176), Expect = 9e-13, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 62/174 (35%), Gaps = 13/174 (7%) Query: 629 ILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITG------------INDPRLRNPSDK 676 ++ + +IV + + N +D + G ++ P DK Sbjct: 79 LIRDLLDNKTDMIVVALSNNAVRKADIDFSLSMMDGGLGALVKSDGTDLSHPLELLNQDK 138 Query: 677 FIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEF 736 + + V + ++ + S E ++ +R FI + + + Sbjct: 139 YQWGVVDSRNPELLLASNQNADYNRIAEDAVKVGSYGEGLERMRAGG-FVFIDEIPGINY 197 Query: 737 EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTW 790 +CD+V GE F G+RK+SP+K V +L E G + EL + Sbjct: 198 ATKGECDIVQIGETFQPFELAFGLRKNSPFKNLVDTFMLGIREQGVISELYAKY 251 >1ISS-A nrPDB Length = 490 Score = 104 bits (260), Expect = 2e-22, Method: Composition-based stats. Identities = 28/195 (14%), Positives = 68/195 (34%), Gaps = 15/195 (7%) Query: 92 VSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVW 151 ++ P + + IP I + SDK+++ FLR VP + QA Sbjct: 124 IAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAM 183 Query: 152 FEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLE- 210 ++++ +NW +V + ++ + G + + L + + + N + Sbjct: 184 LDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAA---QEGLCIAHSDKIYSNAGEKSFDR 240 Query: 211 ------AKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSA----LR 260 + +ARV++ + + L + G + + + Sbjct: 241 LLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGE-FSLIGSDGWADRDEVIEGYE 299 Query: 261 YAPDGIIGLQLINGK 275 +G I ++L + + Sbjct: 300 VEANGGITIKLQSPE 314 >6N4Y-A nrPDB Length = 596 Score = 102 bits (255), Expect = 6e-22, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 69/192 (35%), Gaps = 9/192 (4%) Query: 92 VSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVW 151 + P + + IP I + SDK++ F+R VP + QA Sbjct: 160 IVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAM 219 Query: 152 FEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKV--LQFEPGTKNLTALLL 209 ++++ +NW +V + ++ + G + + + + ++ + G ++ LL Sbjct: 220 VDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLK 279 Query: 210 EAKE--LEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREIS----GSALRYAP 263 + +ARV+ + + L + G ++ L + + Sbjct: 280 KLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGE-FLLLGSDGWADRYDVTDGYQREA 338 Query: 264 DGIIGLQLINGK 275 G I ++L + Sbjct: 339 VGGITIKLQSPD 350 >6N4X-A nrPDB Length = 877 Score = 102 bits (255), Expect = 6e-22, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 69/192 (35%), Gaps = 9/192 (4%) Query: 92 VSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVW 151 + P + + IP I + SDK++ F+R VP + QA Sbjct: 149 IVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAM 208 Query: 152 FEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKV--LQFEPGTKNLTALLL 209 ++++ +NW +V + ++ + G + + + + ++ + G ++ LL Sbjct: 209 VDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLK 268 Query: 210 EAKE--LEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREIS----GSALRYAP 263 + +ARV+ + + L + G ++ L + + Sbjct: 269 KLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGE-FLLLGSDGWADRYDVTDGYQREA 327 Query: 264 DGIIGLQLINGK 275 G I ++L + Sbjct: 328 VGGITIKLQSPD 339 >3LMK-A nrPDB Length = 492 Score = 102 bits (254), Expect = 8e-22, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 68/192 (35%), Gaps = 9/192 (4%) Query: 92 VSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVW 151 + P + + IP I + SDK++ F+R VP + QA Sbjct: 130 IVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAM 189 Query: 152 FEMMRLFNWNHVILIVSDDHEGRAAQKKLE--TLLEEKESKADKVLQFEPGTKNLTALLL 209 ++++ +NW +V + ++ + G + + + + E + G ++ LL Sbjct: 190 VDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGISIAHSYKIYSNAGEQSFDKLLK 249 Query: 210 EAKE--LEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREIS----GSALRYAP 263 + +ARV+ + + L + G ++ L + + Sbjct: 250 KLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGE-FLLLGSDGWADRYDVTDGYQREA 308 Query: 264 DGIIGLQLINGK 275 G I ++L + Sbjct: 309 VGGITIKLQSPD 320 >5TUJ-C nrPDB Length = 235 Score = 93.7 bits (231), Expect = 3e-19, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 19/105 (18%) Query: 453 CYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIV 512 GF +DL LA+E+ E W+G++ L +G+ D+++ Sbjct: 34 YTGFDIDLAKALAKELGVKVEF-----------------VPTTWDGIIPALQTGKFDIVM 76 Query: 513 APLTINNERAQYIEFSKPFKYQGLTILVKKEIP--RSTLDSFMQP 555 + +TI ER + ++FS P+ G TILVKK+ + + +P Sbjct: 77 SGMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIKSFEDLNKP 121 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 13/143 (9%) Query: 653 LVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESA 712 LV ++I D + T + + + + +E+ Sbjct: 103 LVKKDNADKIKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKI----------RTFENN 152 Query: 713 AEAIQAVRDNKLHAFIWDSAVLEFEASQKCDL--VTTGELFFRSGFGIGMRKDSP-WKQN 769 AEA Q V + A + DS V + A + L V E F G +RK P Sbjct: 153 AEAFQEVVSGRADAMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKGDPELLNW 212 Query: 770 VSLNILKSHENGFMEELDKTWVR 792 V+ + + ++G ++L + W + Sbjct: 213 VNNWLKQMKKDGTYDKLYEKWFK 235 >4ZV2-A nrPDB Length = 233 Score = 84.8 bits (208), Expect = 1e-16, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 18/99 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL +A+++ E +++G++ L SG+ D+++A Sbjct: 34 GFDIDLAKAIAKKLGVKVEFK-----------------PMDFDGIIPALQSGKIDVVIAG 76 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEI-PRSTLDSF 552 +TI ER + ++FS P+ G I+VKK +L+ Sbjct: 77 MTITEERKKQVDFSDPYFEAGQAIVVKKGNDSIKSLEDL 115 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 41/229 (17%), Positives = 89/229 (38%), Gaps = 35/229 (15%) Query: 581 FSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMI 640 F PFG N + D + L+ A+ GV + E P F I+ + +G + Sbjct: 20 FPPFGFKDENGKLVGFD-IDLAKAIAKKLGVKV-----EFKPMDFDG-IIPALQSGKIDV 72 Query: 641 IVASYTAN---------------LAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQS 685 ++A T +V+ + + I + D + + V+ Sbjct: 73 VIAGMTITEERKKQVDFSDPYFEAGQAIVVKKGNDSIKSLEDLKGKKVG-------VQLG 125 Query: 686 SVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAV-LEFEAS-QKCD 743 S ++V ++ +++ +EA Q ++ ++ A + D+AV L + Sbjct: 126 STSEQHVKKVAKD---AGVKVKKFDNFSEAFQELKSGRVDAVVTDNAVALAYVKQNPNAG 182 Query: 744 LVTTGELFFRSGFGIGMRKD-SPWKQNVSLNILKSHENGFMEELDKTWV 791 + GE F +GI +RK S + ++ + + ++G +++ + W Sbjct: 183 VKIVGETFSGEPYGIAVRKGNSELLEKINKALEEMKKDGTYDKIYEKWF 231 >4IO3-A nrPDB Length = 248 Score = 84.5 bits (207), Expect = 2e-16, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 69/161 (42%), Gaps = 12/161 (7%) Query: 640 IIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIY---ATVKQSSVDIYFRRQVE 696 I+ S + + + +L R I G++D + + K Y ++ + Y+ R++ Sbjct: 95 IVAFSNSISDNSMRILMRKGTLIDGMDDLK----NGKIPYNRIGIRIGTAGEDYYLREIS 150 Query: 697 LSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQ-KCDLVTTGELFFRSG 755 + + +S E ++ + D E+ + C+L GE F +S Sbjct: 151 GGSR----NFYPLKSRQEMYDSLLAGIIDVSFMDIGTAEYVTNNIYCNLTLVGEDFDKST 206 Query: 756 FGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQEC 796 FGI K+ + +++ +NIL E G ++ L K W + + C Sbjct: 207 FGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKAC 247 Score = 60.2 bits (144), Expect = 4e-09, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 G+ +DL+ L +M F +V L + G++ L +G D+ + Sbjct: 38 TGYVLDLIEYLRDKMGFVADVQLAP-------------PNTSYTGLVLALANGDYDIAIG 84 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 +T+ + R + + FS + IL++K +D Sbjct: 85 DITVTSARREIVAFSNSISDNSMRILMRKGTLIDGMDDL 123 >4MS4-A nrPDB Length = 420 Score = 78.3 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 63/412 (15%), Positives = 129/412 (31%), Gaps = 69/412 (16%) Query: 27 VNIGAVLS-------TKKHEQIFREAVNQAN-KRHFTRKIQLNATSVTHRPNAIQMALSV 78 V IGA+ + + A+ N +R +L + + Q + Sbjct: 6 VYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYL 65 Query: 79 CEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFL 138 E L + + IL+ P T ++ A + + V+ + S++ +F Sbjct: 66 YELLYNDPIKIILM-----PGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFF 120 Query: 139 RTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFE 198 RT P + ++ + W + I L+ L E + ++ + Sbjct: 121 RTHPSATLHNPTRVKLFEKWGWKKIATI---QQTTEVFTSTLDDLEERVKEAGIEITFRQ 177 Query: 199 PGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV--------- 249 + + K +AR+I+ E +A V+ + G YVW + Sbjct: 178 SFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWF 237 Query: 250 ----GEREISGSALRYAPDGIIGLQLI--NGKNE-------------------------- 277 + + A +G I +++ N N Sbjct: 238 KIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEET 297 Query: 278 -----SAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPD 332 + DA+ +A A+++ + N +T M+S + Sbjct: 298 GGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNN--QTITDQIYRAMNSSSFE 355 Query: 333 GVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGS----YIIQNDRKII 380 GV+G + F+ G R I LQ ++G ++ + + D+ I Sbjct: 356 GVSGHVVFDASGSRMAWTL-IEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIG 406 >4PSH-A nrPDB Length = 227 Score = 74.8 bits (182), Expect = 2e-13, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 17/90 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF VDL ++AR + ++ ++G++ LL+ + D+I++ Sbjct: 33 GFDVDLAKEIARRLGVELKI-----------------VDMTFDGLIPSLLTKKIDVIISG 75 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEI 544 +TI ER + + FS P+ G I+V+K+ Sbjct: 76 MTITEERKKVVAFSDPYFDAGQVIVVRKDS 105 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 714 EAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRK-DSPWKQNVSL 772 +A ++ + A + DSA ++ DLV + + +GI +RK D+ + ++ Sbjct: 148 DAFLELKRGRADAVVLDSATARAFVAKNPDLVISSGVLSSEQYGIAVRKEDTDLLEFINS 207 Query: 773 NILKSHENGFMEELDKTWV 791 + + ++ + + L + W Sbjct: 208 VLRELKKSPY-DVLIEKWF 225 >4F3P-A nrPDB Length = 249 Score = 73.7 bits (179), Expect = 4e-13, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 55/137 (40%), Gaps = 18/137 (13%) Query: 417 DGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHL 476 GT + G K+++ +P GF +DL ++A+ +TY++ Sbjct: 9 MGTLEAQTQGPGSMAKELVVGTDTSFMPFEFKQGDKYVGFDLDLWAEIAKGAGWTYKIQ- 67 Query: 477 VADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGL 536 ++ G++ L + D+ ++ +TI ER + I+FS P+ GL Sbjct: 68 ----------------PMDFAGLIPALQTQNIDVALSGMTIKEERRKAIDFSDPYYDSGL 111 Query: 537 TILVK-KEIPRSTLDSF 552 +V+ ++D Sbjct: 112 AAMVQANNTTIKSIDDL 128 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 36/87 (41%), Gaps = 2/87 (2%) Query: 707 HNYESAAEAIQAVRDNKLHAFIWDSA-VLEFEASQKCDLVTT-GELFFRSGFGIGMRKDS 764 + + +A A+ ++ A + D+ VL F ++ V G +GIG K S Sbjct: 155 RQFPNIDQAYLALEAGRVDAAMHDTPNVLFFVNNEGKGRVKVAGAPVSGDKYGIGFPKGS 214 Query: 765 PWKQNVSLNILKSHENGFMEELDKTWV 791 P V+ + + +G ++ K W Sbjct: 215 PLVAKVNAELARMKADGRYAKIYKKWF 241 >2Q2A-A nrPDB Length = 272 Score = 72.1 bits (175), Expect = 1e-12, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 45/121 (37%), Gaps = 17/121 (14%) Query: 432 KKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNS 491 KKV+ P GF VDLL + + YE+ + Sbjct: 42 KKVVVGTDAAFAPFEYMQKGKIVGFDVDLLDAVMKAAGLDYELKNIG------------- 88 Query: 492 NKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDS 551 W+ + L S + DM ++ +TI +ER Q +FS P+ ILVK+ P Sbjct: 89 ----WDPLFASLQSKEVDMGISGITITDERKQSYDFSDPYFEATQVILVKQGSPVKNALD 144 Query: 552 F 552 Sbjct: 145 L 145 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 53/150 (35%), Gaps = 15/150 (10%) Query: 650 AAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNY 709 A ++L + + D + + AT Q + + F + + + Sbjct: 127 ATQVILVKQGSPVKNALDLKGKTI--GVQNATTGQEAAEKLFGKGPHIKK---------F 175 Query: 710 ESAAEAIQAVRDNKLHAFIWDSAV-LEFEASQKCDLVTT---GELFFRSGFGIGMRKDSP 765 E+ AI + + + A I D+AV E+ + + + F +G+ K+S Sbjct: 176 ETTVVAIMELLNGGVDAVITDNAVANEYVKNNPNKKLQVIEDPKNFASEYYGMIFPKNSE 235 Query: 766 WKQNVSLNILKSHENGFMEELDKTWVRYQE 795 K V + +G E+ K W + Sbjct: 236 LKAKVDEALKNVINSGKYTEIYKKWFGKEP 265 >1GGG-A nrPDB Length = 226 Score = 71.4 bits (173), Expect = 2e-12, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 17/113 (15%) Query: 432 KKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNS 491 KK++ +P GF VDL +A+E+ YE+ Sbjct: 3 KKLVVATDTAFVPFEFKQGDLYVGFDVDLWAAIAKELKLDYELK---------------- 46 Query: 492 NKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEI 544 +++G++ L + D+ +A +TI +ER + I+FS + GL ++VK Sbjct: 47 -PMDFSGIIPALQTKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANN 98 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 32/88 (36%), Gaps = 3/88 (3%) Query: 707 HNYESAAEAIQAVRDNKLHAFIWDSAVLEF--EASQKCDLVTTGELFFRSGFGIGMRKDS 764 + + A + N+ A + D+ + + + + G+ +GI K S Sbjct: 134 RQFPNIDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGS 193 Query: 765 P-WKQNVSLNILKSHENGFMEELDKTWV 791 + V+ + ENG E+ K W Sbjct: 194 DELRDKVNGALKTLRENGTYNEIYKKWF 221 >5JOS-A nrPDB Length = 247 Score = 71.0 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 17/91 (18%) Query: 453 CYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIV 512 GF +D+ LA+ + E W +M +L + + D+ + Sbjct: 45 YTGFDIDVAKSLAKSLGVKVEF-----------------VPTTWPTLMSDLQADKFDIAM 87 Query: 513 APLTINNERAQYIEFSKPFKYQGLTILVKKE 543 +T+ ER + +FS P+ G T LV+KE Sbjct: 88 GGVTVTPERQKKADFSDPYMTFGKTPLVRKE 118 >3K4U-A nrPDB Length = 245 Score = 70.6 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 19/103 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF VDL ++A+ M ++ W+G++ L++ + D+I++ Sbjct: 29 GFDVDLAREMAKAMGVKLKL-----------------VPTSWDGLIPGLVTEKFDIIISG 71 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKE--IPRSTLDSFMQP 555 +TI+ ER + F +P+ G ++LVKK + +P Sbjct: 72 MTISQERNLRVNFVEPYIVVGQSLLVKKGLEKGVKSYKDLDKP 114 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 53/154 (34%), Gaps = 13/154 (8%) Query: 641 IVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTM 700 V Y + LV E+ + D + + + + F+ Sbjct: 84 FVEPYIVVGQSLLVKKGLEKGVKSYKDLDKPELTLVTKFGVSAEYAAKRLFKNA------ 137 Query: 701 YRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVL-EFEASQKCD-LVTTGELFFRSGFGI 758 + Y++ AEA+Q V + K FI+D F A + LV G Sbjct: 138 ----KLKTYDTEAEAVQEVLNGKADMFIFDLPFNVAFMAQKGQGYLVHLDTSLTYEPLGW 193 Query: 759 GMRKDSP-WKQNVSLNILKSHENGFMEELDKTWV 791 ++K P + ++ + + +G +EL + W Sbjct: 194 AIKKGDPDFLNWLNHFLAQIKHDGSYDELYERWF 227 >2PYY-A nrPDB Length = 228 Score = 70.2 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Query: 703 HMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEA--SQKCDLVTTGELFFRSGFGIGM 760 H+ EA +A++ K A ++D+ VL F A K + G + +GI + Sbjct: 131 HISVLEVPKIEEAYKALQTKKADAVVFDAPVLLFYAANEGKGKVEIVGSILREESYGIIL 190 Query: 761 RKDSPWKQNVSLNILKSHENGFMEELDKTWVR 792 +SP+++ ++ +L ENG + L W Sbjct: 191 PNNSPYRKPINQALLNLKENGTYQSLYDKWFD 222 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 38/88 (43%), Gaps = 16/88 (18%) Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 GF +DL +A ++ ++ ++ + ++ + + ++ +A Sbjct: 24 SGFSIDLWRSIATQIGIESKLI-----EYSSVPE-----------LISAIKDNKVNLGIA 67 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVK 541 ++I ER Q +FS P GL I+V+ Sbjct: 68 AISITAEREQNFDFSLPIFASGLQIMVR 95 >4F11-A nrPDB Length = 433 Score = 69.8 bits (169), Expect = 6e-12, Method: Composition-based stats. Identities = 50/299 (16%), Positives = 103/299 (34%), Gaps = 52/299 (17%) Query: 118 VIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQ 177 + + +DK + F RTVP + ++++ + W V + D + Sbjct: 112 QLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVR 171 Query: 178 KKLETLLEEKESKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAM 237 L +L + ++ E + + + + K + R+I+ ++ A V+ A Sbjct: 172 NDLTGVL---YGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYE 228 Query: 238 LDMTGAGYVWLVG-----------EREISGSA-----LRYAPDGIIGL------------ 269 +M G+ Y W++ E + S L A +G IG+ Sbjct: 229 ENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKT 288 Query: 270 -------QLINGKNES----------AHISDAVAVVAQAIH-ELFEMENITDPPRGCVGN 311 Q N + D + V+A+ + + + + R N Sbjct: 289 ISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFN 348 Query: 312 TNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGS 370 G + + + + GVTG++ F +G+R Q+ + V+VG +N Sbjct: 349 YTDHTLGRIILNAMNETNFF-GVTGQVVF-RNGERMG-TIKFTQFQDSREVKVGEYNAV 404 >4YMX-A nrPDB Length = 260 Score = 68.3 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 44/98 (44%), Gaps = 17/98 (17%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +D+ +A+++ E+ ++ G++ L +G+ DM++A Sbjct: 64 GFDIDIANAIAKKLGVKLEIK-----------------DMDFKGLIPALQAGRVDMVIAG 106 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 +T ER + ++FS + ++VK + P S D Sbjct: 107 MTPTAERKKSVDFSDLYYDSRQVVVVKNDSPISKFDDL 144 Score = 34.8 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 29/232 (12%), Positives = 82/232 (35%), Gaps = 39/232 (16%) Query: 581 FSPFGRFKVNSEEEE--EDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFA 638 F PF KV ++E + +++A+ GV L I + + + + AG Sbjct: 47 FPPFEFHKVEGGKDEIVGFDIDIANAIAKKLGVKLE--IKDMDFKGL----IPALQAGRV 100 Query: 639 MIIVASYTANL--------------AAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQ 684 +++A T + +V+ + + I+ +D +++ V+ Sbjct: 101 DMVIAGMTPTAERKKSVDFSDLYYDSRQVVVVKNDSPISKFDDLKVKTI-------AVQI 153 Query: 685 SSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEAS--QKC 742 + ++ ++ ++ +++ + A + + V + + Sbjct: 154 GTTSE--EAAKKIPN----VKLKQLNRVSDEFMDLQNGRCDAIVVEDTVAKAYLKEYKDM 207 Query: 743 DLVTTGELFFRS-GFGIGMRKDS-PWKQNVSLNILKSHENGFMEELDKTWVR 792 ++ E+ G + + K + V+ I + ++G ++L W + Sbjct: 208 KILYMDEINNVENGSAVAVAKGNKSLLDVVNEVIKELKQSGEYDKLVDKWFK 259 >4ZEF-A nrPDB Length = 251 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 17/102 (16%) Query: 453 CYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIV 512 G VDL+ + A FT E + ++ + + SGQAD +V Sbjct: 50 YVGIDVDLVKRAAELQGFTVEFKFIG-----------------FSSAVQAVESGQADGMV 92 Query: 513 APLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 A +TI ++R + +FS P+ G+ I VKK + ++ Sbjct: 93 AGMTITDDRKKAFDFSVPYFDSGIQIAVKKGNDKIKSYDDLK 134 >1YK0-A nrPDB Length = 480 Score = 64.4 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 58/399 (14%), Positives = 123/399 (30%), Gaps = 61/399 (15%) Query: 32 VLSTKKHEQIFREAVNQANKRHFTRKIQLNAT--------SVTHRPNAIQMALSVCEDLI 83 + S + A+ R++ T S + V Sbjct: 66 LFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARG 125 Query: 84 SSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDK-SIHLSFLRTVP 142 + P P++ A + +P++ + + K S + R P Sbjct: 126 AKPDL------ILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAP 179 Query: 143 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLE--EKESKADKVLQFEPG 200 Y+ + + R +W+ L+ SDD R LE + E ++E + F+ Sbjct: 180 AYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDET 239 Query: 201 TKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALR 260 ++ + RV+I+ AS D ++ A MT Y + E+ S+ Sbjct: 240 KDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFF--NIELFNSSSY 297 Query: 261 YAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGN--------- 311 G E+ ++ V E E + + V Sbjct: 298 GDGSWKRG---DKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYV 354 Query: 312 ------------------TNIWKTGPLFK---RVLMS--SKYPDGVTGRIEFNEDGDRKF 348 + + G K +++ ++ +G+ G++ + +GDR + Sbjct: 355 NMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDR-Y 413 Query: 349 ANYSIMNLQNRKL---VQVGIFNGSYIIQNDR---KIIW 381 ++S++ + + + +G + G R K W Sbjct: 414 GDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPW 452 >5EYF-A nrPDB Length = 245 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 14/102 (13%) Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 + GF VD+ + +++ L +GK E + + + L +G D Sbjct: 36 RTVQGFDVDIAKAITKKI-------LGDNGKTEFVEVTSKTR-------IPLLKNGNIDA 81 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 I+A +TI +ER + ++FS + G +LVKK ++D Sbjct: 82 IIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDL 123 Score = 52.5 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 47/112 (41%), Gaps = 7/112 (6%) Query: 681 TVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQ 740 VK S+ R+ + + E+ AEA A++ + A D+A+L A + Sbjct: 131 AVKGSTSAANIRQHAPDAKI------LELENYAEAFTALQSGQGDAMTTDNAILLGIADE 184 Query: 741 KCDLVTTGELFFRSGFGIGMRKDSP-WKQNVSLNILKSHENGFMEELDKTWV 791 + G F +GI + K + + V+ + + H +G +++ + W Sbjct: 185 NPEYELVGGTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWF 236 >4G4P-A nrPDB Length = 244 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 45/102 (44%), Gaps = 17/102 (16%) Query: 453 CYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIV 512 G VDLL +A++ +F ++ + ++ + + S Q D ++ Sbjct: 45 YIGIDVDLLDAIAKDQDFEVDLKPLG-----------------FDSAVQAIQSKQIDGMI 87 Query: 513 APLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 A ++I +ER + +FS P+ GL + VKK + ++ Sbjct: 88 AGMSITDERKKSFDFSDPYFDSGLQLAVKKGNDKIKSYDDLK 129 Score = 37.1 bits (84), Expect = 0.037, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 52/136 (38%), Gaps = 12/136 (8%) Query: 653 LVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESA 712 L + + ++I +D + + + K + F + + Y + K N++ A Sbjct: 113 LAVKKGNDKIKSYDDLKGKTVAAKV-------GTESANFLEKNK--EKYDYTIK-NFDDA 162 Query: 713 AEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDS--PWKQNV 770 +A+ + + A + D VL + L G+ S +G ++K + Sbjct: 163 TGLYKALENGEADAIVDDYPVLGYAVKNGQKLQLVGDKETGSSYGFAVKKGQNPELIKKF 222 Query: 771 SLNILKSHENGFMEEL 786 + + +NG +++ Sbjct: 223 NAGLKNLKDNGTYDKI 238 >4F3S-A nrPDB Length = 255 Score = 59.0 bits (141), Expect = 9e-09, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 30/42 (71%) Query: 490 NSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPF 531 N + W+GM+G + SGQAD+ + ++I ++R + I+FS+P+ Sbjct: 51 NITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPY 92 Score = 34.0 bits (76), Expect = 0.31, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 40/110 (36%), Gaps = 8/110 (7%) Query: 675 DKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLH-AFIWDSAV 733 +K+ + + + +E Y + Y + E + +++ L AFI + Sbjct: 116 NKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKNGNLDLAFIEEPVY 175 Query: 734 LEFEASQ--KCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENG 781 F+ + + + + GI +K SP + + + L E G Sbjct: 176 FTFKNKKKMPIESRYVFKNVDQ--LGIAFKKGSPVRDDFN---LWLKEQG 220 >4H5F-A nrPDB Length = 243 Score = 57.1 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 17/88 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G +D+ +A E+ E+ ++ ++ L +G+AD+ VA Sbjct: 39 GADIDMAQAIADELGVKLEI-----------------LSMSFDNVLTSLQTGKADLAVAG 81 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKK 542 ++ +ER + +FS P+ ++ LV K Sbjct: 82 ISATDERKEVFDFSIPYYENKISFLVHK 109 >5OTA-A nrPDB Length = 265 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 17/91 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL L + MN + ++ W+G++ L +G+ D I+A Sbjct: 29 GFDIDLGNDLCKRMNIECKF-----------------VEQAWDGIIPSLTAGRYDAIMAA 71 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 + I R + I FS+P+ +T L + P Sbjct: 72 MGIQPAREKVIAFSRPYLLTPMTFLTTADSP 102 >4I62-A nrPDB Length = 269 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 41/89 (46%), Gaps = 17/89 (19%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 G ++L +A E+ E+ + ++ ++ + SG+AD+ ++ Sbjct: 66 GSDIELAKAIATELGVELEL-----------------SPMSFDNVLASVQSGKADLAISG 108 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKE 543 ++ +ER++ +FS P+ ++VKK Sbjct: 109 VSKTDERSKVFDFSTPYYTAKNKLIVKKS 137 Score = 50.2 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 42/217 (19%), Positives = 79/217 (36%), Gaps = 18/217 (8%) Query: 581 FSPFGRFKVNSEEEE--EDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFA 638 F+PF KV + + + L+ A+ GV L E +P SF +L V +G A Sbjct: 49 FAPFEYQKVVDGKNQIVGSDIELAKAIATELGVEL-----ELSPMSFDN-VLASVQSGKA 102 Query: 639 MIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELS 698 + ++ + V D + + SD Y +V + ++ + Sbjct: 103 DLAISGVSKTDERSKVFD-FSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ 161 Query: 699 TMYRH-----MEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFR 753 + I ++ ++ A I++ V + DL F + Sbjct: 162 ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNFEK 221 Query: 754 S---GFGIGMRKDSP-WKQNVSLNILKSHENGFMEEL 786 + + M+KDS K+ V I K E+G +++L Sbjct: 222 EQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKL 258 >3TQL-A nrPDB Length = 227 Score = 52.5 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 37/91 (40%), Gaps = 17/91 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF D++ + ++M + V + + W+ ++ L G+ D + Sbjct: 26 GFGADIVKAVCKQM-----------------QAVCTISNQPWDSLIPSLKLGKFDALFGG 68 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 + I R + ++F+ P+ ++ + K P Sbjct: 69 MNITTARQKEVDFTDPYYTNSVSFIADKNTP 99 >3A3K-A nrPDB Length = 435 Score = 52.5 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 55/341 (16%), Positives = 113/341 (33%), Gaps = 60/341 (17%) Query: 96 PAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMM 155 P + P+ +R+P++ K + RT P + + Sbjct: 82 LGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALH 141 Query: 156 RLFNWNHVILIVSDDHEGRA-----AQKKLETLLEEKESKADKVLQFEPGTKNLTALLLE 210 R W H L++ D G + L + E+ + +F G + LL Sbjct: 142 RRLGWEHQALVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLLR 201 Query: 211 AKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIG-- 268 A + RVI + +S D + A +TG Y + ++ G +L+ + G++ Sbjct: 202 AVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDY--VFFHLDVFGQSLK-SAQGLVPQK 258 Query: 269 ---------------------LQLINGKNESAH-----------------ISDAVA-VVA 289 + N + D + ++ Sbjct: 259 PWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTVEDGLKNIIP 318 Query: 290 QAIHE--LFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDR- 346 + H+ L ++ +T+ + G + M ++ GVTG ++ + +GDR Sbjct: 319 ASFHDGLLLYVQAVTET----LAQGGTVTDGENITQR-MWNRSFQGVTGYLKIDRNGDRD 373 Query: 347 KFANYSIMNLQNRKLVQVGIFNGSY---IIQNDRKIIWPGG 384 + M+ + V +NG+ + ++ K+ WP G Sbjct: 374 TDFSLWDMDPETGAFRVVLNYNGTSQELMAVSEHKLYWPLG 414 >6FXG-A nrPDB Length = 227 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 17/102 (16%) Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 + G VD++ ++A+ ++ E+ ++ + L +GQ D Sbjct: 24 KKWVGIDVDIMQEVAKINDWKLEMSYPG-----------------FDAALQNLKAGQVDG 66 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 I+A +TI +ER + +FS P+ LTI K+ S Sbjct: 67 IIAGMTITDERKETFDFSNPYYTSALTIATTKDSKLSDYSDL 108 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 12/90 (13%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 707 HNYESAAEAI---QAVRDNKLHAFIWDSAVLEFEASQKCDL-VTTGELFFRSGFGIGMRK 762 + ++ ++ + A+ + + + V+ + Q DL + + G+G + K Sbjct: 134 YTIKTYSDGVHMFAALSSGNIAGAMDEVPVISYAMKQGQDLAMNFPSISLPGGYGFAVMK 193 Query: 763 D--SPWKQNVSLNILKSHENGFMEELDKTW 790 S + + + NG +++ K + Sbjct: 194 GKNSTLVDGFNKALAEMKSNGDYDKILKKY 223 >4KPT-A nrPDB Length = 251 Score = 51.7 bits (122), Expect = 2e-06, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 17/102 (16%) Query: 451 QCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADM 510 + G VD++ ++A+ ++ E+ ++ + L +GQ D Sbjct: 48 KKWVGIDVDIMQEVAKINDWKLEMSYPG-----------------FDAALQNLKAGQVDG 90 Query: 511 IVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 I+A +TI +ER + +FS P+ LTI K+ S Sbjct: 91 IIAGMTITDERKETFDFSNPYYTSALTIATTKDSKLSDYSDL 132 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 12/90 (13%), Positives = 35/90 (38%), Gaps = 6/90 (6%) Query: 707 HNYESAAEAI---QAVRDNKLHAFIWDSAVLEFEASQKCDL-VTTGELFFRSGFGIGMRK 762 + ++ ++ + A+ + + + V+ + Q DL + + G+G + K Sbjct: 158 YTIKTYSDGVHMFAALSSGNIAGAMDEVPVISYAMKQGQDLAMNFPSISLPGGYGFAVMK 217 Query: 763 D--SPWKQNVSLNILKSHENGFMEELDKTW 790 S + + + NG +++ K + Sbjct: 218 GKNSTLVDGFNKALAEMKSNGDYDKILKKY 247 >5HPQ-A nrPDB Length = 255 Score = 50.9 bits (120), Expect = 3e-06, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 30/83 (36%), Gaps = 17/83 (20%) Query: 453 CYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIV 512 GF VD+ +LA + W +M + + D+ + Sbjct: 45 YAGFDVDMAQRLAESLGAK-----------------LVVVPTSWPNLMRDFADDRFDIAM 87 Query: 513 APLTINNERAQYIEFSKPFKYQG 535 + ++IN ER + FS P+ G Sbjct: 88 SGISINLERQRQAYFSIPYLRDG 110 >5LOM-A nrPDB Length = 269 Score = 49.4 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 35/73 (47%) Query: 469 NFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFS 528 F E+ L G+ G ++ +E++ +M + +G+ D+ A + +R + ++FS Sbjct: 55 GFDIELFLNVAGRLGFKKEQVVFTGQEFSALMPSVANGRFDVAAAAIGTTAKRKETVDFS 114 Query: 529 KPFKYQGLTILVK 541 + L++L Sbjct: 115 DGYLAGFLSVLTS 127 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 53/149 (35%), Gaps = 14/149 (9%) Query: 649 LAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHN 708 LA FL + E IT + + + T+++ + F + Sbjct: 118 LAGFLSVLTSEAGITDAAGLKGKRL--GVVQGTLQEIYAEKNFAGTDLV----------K 165 Query: 709 YESAAEAIQAVRDNKLHA-FIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSP-W 766 + A+ A+ + + A F+ A ++ A + F + G +RK + Sbjct: 166 FPDNNSAVSALNNGTVDAHFLDFEAAKDYSARYPALKIAVNIPSFDAPAGFVIRKGNDAL 225 Query: 767 KQNVSLNILKSHENGFMEELDKTWVRYQE 795 + + + ++ ++G ++L + W Sbjct: 226 RNALDKGLKEAMQDGTWKKLHEKWFPGTP 254 >4OEN-A nrPDB Length = 223 Score = 49.4 bits (116), Expect = 8e-06, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 41/100 (41%), Gaps = 17/100 (17%) Query: 453 CYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIV 512 G ++L+ +A++ F E+ ++ + + +GQAD I+ Sbjct: 25 YTGIDMELIKAIAKDQGFEIEITNPG-----------------FDAAISAVQAGQADGII 67 Query: 513 APLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSF 552 A +++ + R +FS+ + + VK+ ++ + Sbjct: 68 AGMSVTDARKATFDFSESYYTANTILGVKESSNIASYEDL 107 >3I6V-A nrPDB Length = 232 Score = 49.0 bits (115), Expect = 9e-06, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 27/41 (65%) Query: 492 NKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFK 532 K +W+ ++ L+SG D I+A ++I +ER + I+F++ + Sbjct: 49 VKNDWDSIIPNLVSGNYDTIIAGMSITDERDEVIDFTQNYI 89 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 34/88 (38%), Gaps = 5/88 (5%) Query: 708 NYESAAEAIQAVRDNKLHA-FIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGM---RKD 763 + + E I AVR+ + A F ++ A +L+ G+ G G+GM D Sbjct: 130 EFATPEETIAAVRNGEADAVFADRDYLVPIVAESGGELMFVGDDVPLGG-GVGMGLRESD 188 Query: 764 SPWKQNVSLNILKSHENGFMEELDKTWV 791 + I E+G + + K W Sbjct: 189 GELRGKFDAAITSMKEDGTLNTMIKKWF 216 >3VV5-A nrPDB Length = 260 Score = 49.0 bits (115), Expect = 1e-05, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 17/97 (17%) Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 GF VDL +A + + ++ ++ +L G+ D ++A Sbjct: 59 TGFEVDLGNAIAERLGLK-----------------PRWIAQSFDTLLIQLNQGRFDFVIA 101 Query: 514 PLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLD 550 I ERA+ ++F+ P G I+ +K PR+ D Sbjct: 102 SHGITEERARAVDFTNPHYCTGGVIVSRKGGPRTAKD 138 Score = 34.0 bits (76), Expect = 0.33, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 36/88 (40%), Gaps = 3/88 (3%) Query: 707 HNYESAAEAIQAVRDNKLHAFIWDS--AVLEFEASQKCDLVTTGELFFRSGFGIGMRKDS 764 Y+ +A+Q + ++ +I D A + + + + GEL F+ + + K + Sbjct: 166 RTYQRDPDALQDLLAGRIDTWITDRFVAKEAIKERKLENTLQVGELVFQERVAMAVAKGN 225 Query: 765 -PWKQNVSLNILKSHENGFMEELDKTWV 791 ++ + + ++G + + W Sbjct: 226 KSLLDALNRALAELMQDGTYARISQKWF 253 >5ORE-A nrPDB Length = 263 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 17/77 (22%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL L +M ++ + W+G+M L + D I+A Sbjct: 28 GFEIDLANALCEKMKAKCQI-----------------VAQNWDGIMPSLTGKKYDAIMAA 70 Query: 515 LTINNERAQYIEFSKPF 531 +++ +R + I FS P+ Sbjct: 71 MSVTPKRQEVIGFSIPY 87 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 25/123 (20%) Query: 684 QSSV------DIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFE 737 Q S D YF+ V++ Y+S E + +L A + ++ VL Sbjct: 140 QGSTTASTFLDKYFKGSVDIKE---------YKSVEEHNLDLTSGRLDAVLANATVLAAA 190 Query: 738 ASQK----CDLVTTGELFFRSGFGI---GMRK-DSPWKQNVSLNILKSHENGFMEELDKT 789 + L G LF FG+ G+RK D+ K + I + E+G ++ L Sbjct: 191 IEKPEMKGAKL--VGPLFSGGEFGVVAVGLRKEDTALKADFDAAIKAASEDGTIKTLSLK 248 Query: 790 WVR 792 W + Sbjct: 249 WFK 251 >2IEE-A nrPDB Length = 271 Score = 45.9 bits (107), Expect = 8e-05, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 48/142 (33%), Gaps = 19/142 (13%) Query: 413 PTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTY 472 S T E+ G + + + G+ V+++ + A+ + Sbjct: 6 EADSKDTGWEQIKDKGKIVVATSGTLYPTSYHDTDSGSDKLTGYEVEVVREAAKRLGLKV 65 Query: 473 EVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFK 532 E + +GM+ + SGQ D + + +R + FS P+K Sbjct: 66 EFKEMGI-----------------DGMLTAVNSGQVDAAANDIDVTKDREEKFAFSTPYK 108 Query: 533 YQGLTILVKKE--IPRSTLDSF 552 Y T +V+K+ TL Sbjct: 109 YSYGTAIVRKDDLSGIKTLKDL 130 >2Y7I-A nrPDB Length = 229 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 38/86 (44%), Gaps = 18/86 (20%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +D+ + +EM + + + ++ ++ L + D ++A Sbjct: 30 GFDIDVANAVCKEM-----------------QAECSFTNQSFDSLIPSLRFKKFDAVIAG 72 Query: 515 LTINNERAQYIEFSKPFKYQGLTILV 540 + + +R Q + FS+P+ GL+ +V Sbjct: 73 MDMTPKREQQVSFSQPYYE-GLSAVV 97 >4KQP-A nrPDB Length = 232 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 17/85 (20%) Query: 454 YGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVA 513 G VDLL +A+ F + + + G Q V++ +GMM + Sbjct: 31 TGIDVDLLNAIAKNQGFKLKWNFI-----GFQAAVDSVQSGHADGMM------------S 73 Query: 514 PLTINNERAQYIEFSKPFKYQGLTI 538 ++I + R Q ++ P+ LTI Sbjct: 74 GMSITDARKQVFDYGSPYYSSNLTI 98 Score = 38.2 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 18/171 (10%), Positives = 54/171 (31%), Gaps = 7/171 (4%) Query: 630 LGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSV-- 687 + V +G A +++ + A V D + + D + Sbjct: 60 VDSVQSGHADGMMSGMSITDARKQVFDYGSPYYSSNLTIATSSTDDSIKSWKDLKGKTLG 119 Query: 688 DIYFRRQVELSTMYRHMEKHNYESAAEAIQ---AVRDNKLHAFIWDSAVLEFEASQKCDL 744 + + + ++ +A ++ + ++A + D V+++ Q Sbjct: 120 AKNGTASFDYLNAHAKEYGYTVKTFTDATTMYSSLNNGSINALMDDEPVIKYAIKQGQKF 179 Query: 745 VTTGELFFRSGFGIGMRKDS--PWKQNVSLNILKSHENGFMEELDKTWVRY 793 T + +G ++K S + + + NG +++ ++ Sbjct: 180 ATPIKPIPDGQYGFAVKKGSNPELIEMFNNGLANLRANGEYDKIIDKYLES 230 >4MLC-A nrPDB Length = 356 Score = 43.2 bits (100), Expect = 6e-04, Method: Composition-based stats. Identities = 41/358 (11%), Positives = 97/358 (27%), Gaps = 32/358 (8%) Query: 27 VNIGAVLSTKKHEQIFRE----AVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDL 82 + IG + +F E AV + N++ + +L+ + Sbjct: 11 IFIGVAWPFASLDDLFAEGLELAVQEINEQGGVQGRKLSLVKADDEAELEKGLAIAQAFA 70 Query: 83 ISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP 142 ++ + A++ + P + + ++ + +D ++ R +P Sbjct: 71 DNAGIQAVI-----GHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDHG-YIHVFRNIP 124 Query: 143 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTK 202 A + +++ +DD G E + + K Sbjct: 125 SDQEIARQLAIYLAEQGHERMVIYYTDDSYGNGLANAFEDYARAQGITIVDRFNYYGNLK 184 Query: 203 NLTALLLEAKE-LEARVIILSASEDDATAVYKSAAMLDM---TGAGYVWLVGEREISGSA 258 +L L + + + I + T A + + AG W Sbjct: 185 DLERLYDKWQAFGMDGIFIAKTATGGGTEFLVDAKSVGIEVPLIAGNSWDALSLTEDIEN 244 Query: 259 LRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNI---- 314 + +G++ N + + D V +A G + Sbjct: 245 IGMTAEGLLVGSFFNPQRPDSRTQDFV----EAFR---REYGQPPTSYAAAGYDAVILLA 297 Query: 315 -------WKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVG 365 + L +GV G F+ GD + +++ + +G Sbjct: 298 EALEKSDLTHPATLAQGLRDLGPWEGVMGMHRFDGRGDDIGDLVVLKKMKDGRFEYLG 355 >5OWF-A nrPDB Length = 259 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 39/99 (39%), Gaps = 18/99 (18%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL ++ + M +++ ++ L + + D I++ Sbjct: 49 GFDIDLGNEMCKRMQVK-----------------CTWVASDFDALIPSLKAKKIDAIISS 91 Query: 515 LTINNERAQYIEFSKPFKYQGLTILVKKEIPR-STLDSF 552 L+I ++R Q I FS ++ K P TL+S Sbjct: 92 LSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQPTLESL 130 >3IP9-A nrPDB Length = 356 Score = 42.9 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 38/301 (12%), Positives = 76/301 (25%), Gaps = 22/301 (7%) Query: 64 SVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTT 123 V+ I +A D + V + + + G I Sbjct: 51 DVSDPKQGISVANKFVADGVK------FVVGHFNSGVSIPASEVYAENGILE---ITPAA 101 Query: 124 RMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETL 183 +++++ + +F + + F V +I G+ + + Sbjct: 102 TNPVFTERGLWNTFRTCGRDDQQGGIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKA 161 Query: 184 LEEKESKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGA 243 G K+ +AL+ + KE +I +A + + AA + Sbjct: 162 ANAAGVTEVMYEGVNVGDKDFSALISKMKEAGVSIIYWGGLHTEAGLIIRQAADQGLKAK 221 Query: 244 GYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIH-------ELF 296 LV I + L + L N + + + Sbjct: 222 ----LVSGDGIVSNELASIAGDAVEGTL-NTFGPDPTLRPENKELVEKFKAAGFNPEAYT 276 Query: 297 EMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNL 356 L +P + G I F+E GD K Y + Sbjct: 277 LYSYAAMQAIAGAAKAAGSVEPEKVAEALKKGSFPTAL-GEISFDEKGDPKLPGYVMYEW 335 Query: 357 Q 357 + Sbjct: 336 K 336 >4GNR-A nrPDB Length = 353 Score = 42.9 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 50/352 (14%), Positives = 104/352 (29%), Gaps = 53/352 (15%) Query: 35 TKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDLISSQVYAILVSH 94 ++ + AV++ N Q+ ++ + A + S+V A++ Sbjct: 24 GTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTNLVTQSKVSAVV--- 80 Query: 95 PPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEM 154 P A +P+I + + +L S Q + Sbjct: 81 --GPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTF--QDSFQGKIISNY 136 Query: 155 MRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFEPGTKNLTALLLEAKEL 214 + N +++ D+ A+ ++ E + + F G + A L + K Sbjct: 137 VSE-KLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDFQAALTKMKGK 195 Query: 215 EARVIILSASEDDATAVYKSAAMLDM----------TGAGYVWLVGEREISGSALRYAPD 264 + I++ ++A + A + + G +V + S Sbjct: 196 DFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAEKASNIYFISGFS 255 Query: 265 GIIGLQLI--------------NGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVG 310 + + +A D+V +VA A Sbjct: 256 TTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGA--------------- 300 Query: 311 NTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLV 362 K K L +K +GVTG+ F+ D + Y +M + N K+ Sbjct: 301 -----KNSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAY-MMTMNNGKVE 346 >1HSL-A nrPDB Length = 238 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 41/126 (32%), Gaps = 18/126 (14%) Query: 428 GDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQER 487 P K I P GF +DL +L + +N Sbjct: 1 AIPQKIRIGTDPTYAPFESKNAQGELVGFDIDLAKELCKRIN-----------------T 43 Query: 488 VNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPR- 546 + + ++ L + + D I++ L+I +R Q I F+ ++V K Sbjct: 44 QCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKNSDIQ 103 Query: 547 STLDSF 552 T+ S Sbjct: 104 PTVASL 109 >1IIT-A nrPDB Length = 232 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 26/43 (60%), Gaps = 2/43 (4%) Query: 500 MGELLSGQADMIVAPLTINNERAQY--IEFSKPFKYQGLTILV 540 + + G+ D+++ P+++ ERA I F++P+ G+ +L+ Sbjct: 58 ITAVAEGELDILIGPISVTPERAAIEGITFTQPYFSSGIGLLI 100 Score = 36.3 bits (82), Expect = 0.061, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 715 AIQAVRDNKLHAFIWDSAVLEFEASQKCDL-VTTGEL-FFRSGFGIGMRKDSPWKQNVSL 772 AI ++ ++ A ++D L + Q +L + E+ +G ++++SP ++ +++ Sbjct: 147 AITLLQKKQVEAVMFDRPALIYYTRQNPNLNLEVTEIRVSLEPYGFVLKENSPLQKTINV 206 Query: 773 NILKSHENGFMEELDKTWVRYQE 795 +L + + E + W+ Sbjct: 207 EMLNLLYSRVIAEFTERWLGPGI 229 >4Q0C-A nrPDB Length = 584 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 499 MMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQ 554 ++ +L SG+ADM L +N+ R ++ FS+P+ G+ I+ +++ + Sbjct: 392 LIAKLRSGEADMA-GALFVNSARESFLSFSRPYVRNGMVIVTRQDPDAPVDADHLD 446 >3DEL-B nrPDB Length = 242 Score = 36.7 bits (83), Expect = 0.052, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 35/86 (40%), Gaps = 18/86 (20%) Query: 455 GFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 514 GF +DL +++ ++ T +V + ++ ++ L + D ++ Sbjct: 35 GFDIDLAREISNKLGKTLDVR-----------------EFSFDALILNLKQHRIDAVITG 77 Query: 515 LTINNERAQYIEFSKPFKYQGLTILV 540 ++I R + I P+ + + LV Sbjct: 78 MSITPSRLKEI-LMIPYYGEEIKHLV 102 >2Q88-A nrPDB Length = 257 Score = 35.2 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%) Query: 495 EWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIP 545 E+ M+ L +G+ D I A L + ER + +S+P +KK P Sbjct: 60 EYGAMIPGLQAGRHDAITAGLFMKPERCAAVAYSQPILCDAEAFALKKGNP 110 >2A79-B nrPDB Length = 499 Score = 32.8 bits (73), Expect = 0.74, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 40/105 (38%), Gaps = 8/105 (7%) Query: 539 LVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDA 598 L + L ++ L LL+ V + FS F ++E + Sbjct: 307 LSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL-------FSSAVYF-AEADERDSQF 358 Query: 599 LTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVA 643 ++ A W++ + G G+ P + +I+G + A ++ +A Sbjct: 359 PSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIA 403 >4JTA-B nrPDB Length = 514 Score = 32.5 bits (72), Expect = 0.96, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 40/105 (38%), Gaps = 8/105 (7%) Query: 539 LVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDA 598 L + L ++ L LL+ V + FS F ++E + Sbjct: 322 LSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL-------FSSAVYF-AEADERDSQF 373 Query: 599 LTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVA 643 ++ A W++ + G G+ P + +I+G + A ++ +A Sbjct: 374 PSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIA 418 >4CHV-A nrPDB Length = 361 Score = 31.7 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 11/70 (15%) Query: 563 LVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAP 622 L G+ + VA+ Y+++R + + E ++ AMW++ L +G G+ P Sbjct: 135 LFGVVLFAVALAAYVIER-----------DIQPEKFGSIPQAMWWAVVTLSTTGYGDTIP 183 Query: 623 RSFSARILGM 632 +SF+ R+L Sbjct: 184 QSFAGRVLAG 193 >6G72-J nrPDB Length = 172 Score = 30.1 bits (66), Expect = 3.9, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 14/88 (15%) Query: 561 WLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSW-----GVLLNS 615 WL++G V V + ++L+ + + V + + D W + GV+L Sbjct: 86 WLILGFLVLGVIMEVFLICVLNYYDEVGVINLDGLGD--------WLMYEVDDVGVMLEG 137 Query: 616 GIGEGAPRSFSA-RILGMVWAGFAMIIV 642 GIG A S + ++ W+ FA I + Sbjct: 138 GIGVAAMYSCATWMMVVAGWSLFAGIFI 165 >5NTF-A nrPDB Length = 520 Score = 29.8 bits (65), Expect = 5.6, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 14/30 (46%) Query: 710 ESAAEAIQAVRDNKLHAFIWDSAVLEFEAS 739 + AEAIQ V+ + +A + + E Sbjct: 68 PAVAEAIQRVKKGETYAVLAEGVKNEANER 97 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.124 0.308 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,496,699 Number of Sequences: 36641 Number of extensions: 1037267 Number of successful extensions: 3237 Number of sequences better than 10.0: 97 Number of HSP's better than 10.0 without gapping: 160 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 2598 Number of HSP's gapped (non-prelim): 279 length of query: 903 length of database: 10,336,785 effective HSP length: 106 effective length of query: 797 effective length of database: 6,452,839 effective search space: 5142912683 effective search space used: 5142912683 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)