single cell Hi-C normalization

Inferring single-cell 3D chromosomal structures based on Lennard-Jones potential


LJ3D is a computational method to reconstruct high-resolution 3D chromosome structures based on the zero-inflated single-cell Hi-C data.

Download


The C++ source code and a user manual of LJ3D can be downloaded from here.

Reference


Zha,M.Wang,N.Zhang,C and Wang,Z. (2021) Inferring single-cell 3D chromosomal structures based on Lennard-Jones potential. International Journal of Molecular Sciences, under review.

Contact


For any questions or suggestions, please contact:
Dr. Zheng Wang
Department of Computer Science
University of Miami